Texas Instruments

THS4522 - Very Low Power Dual Fully Differential Amp | TI

MPN: THS4522 βœ“ Active
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2.5 V to 5.5 V Vdss 1.1 mA Id 16-TSSOP (PW) Package
From $2.19 USD / Unit
MOQ: 1 |
Price updated: 2026-08-25
Volume Pricing
Qty Unit Price Extended
1 $3.42 $3.42
10 $3.08 $30.80
100 $2.74 $274.00
500 $2.47 $1,235.00
1,000 $2.19 $2,190.00
ℹ️ All prices are in USD

Drop-in alternatives for THS4522 β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

THS4552

βœ… Drop-In
πŸ“¦ 16-TSSOP
Higher bandwidth (150 MHz) and lower noise (3.3 nV/√Hz), but higher quiescent current (1.35 mA/ch)

πŸ“‹ Reference alternative (not in catalog)

THS4521

βœ… Drop-In
πŸ“¦ 16-TSSOP
Single-channel version, same package and pinout for channel 1

πŸ“‹ Reference alternative (not in catalog)

THS4524

βœ… Drop-In
πŸ“¦ 16-TSSOP
Quad-channel version, same package and pinout for channels 1-4

πŸ“‹ Reference alternative (not in catalog)

LMH6552

βœ… Drop-In
πŸ“¦ 16-TSSOP
Higher bandwidth (1.5 GHz) and slew rate (2400 V/Β΅s), but higher power (20 mA quiescent)

πŸ“‹ Reference alternative (not in catalog)

ADA4932-2

βœ… Drop-In
πŸ“¦ 16-TSSOP
Dual FDA with 560 MHz bandwidth, but higher noise (3.5 nV/√Hz) and power (9.6 mA/ch)

πŸ“‹ Reference alternative (not in catalog)

LTC6400-20

βœ… Drop-In
πŸ“¦ 16-TSSOP
Dual FDA with 2 GHz bandwidth, but much higher power (50 mA/ch)

πŸ“‹ Reference alternative (not in catalog)

THS4522 Maximum Ratings & Electrical Characteristics

Number of Channels 2
Amplifier Type Fully Differential
Supply Voltage Range 2.5 V to 5.5 V
Bandwidth (Gain=1) 95 MHz
Slew Rate 100 V/Β΅s
Input Voltage Noise 4.6 nV/√Hz
Quiescent Current per Channel 1.1 mA
Output Current 55 mA
Offset Voltage 0.5 mV
Rail-to-Rail Output Yes
Negative Rail Input Yes
Enable Pin Yes
Operating Temperature Range -40Β°C to +125Β°C
Package 16-TSSOP (PW)
RoHS Status Compliant

THS4522 Pin Configuration

SOIC-16 Package Pinout Diagram SOIC-16 16-pin, 3.9x9.9mm, P1.27mm, JEDEC MS-012. 1 16 2 15 3 14 4 13 5 12 6 11 7 10 8 9 SOIC-16
Pin 1 OUT1- β€” Inverting output of channel 1
Pin 2 OUT1+ β€” Non-inverting output of channel 1
Pin 3 VCC β€” Positive power supply
Pin 4 VOCM1 β€” Output common-mode voltage control for channel 1
Pin 5 PD1 β€” Power-down for channel 1 (active low)
Pin 6 IN1- β€” Inverting input of channel 1
Pin 7 IN1+ β€” Non-inverting input of channel 1
Pin 8 VEE β€” Negative power supply (or ground)
Pin 9 IN2+ β€” Non-inverting input of channel 2
Pin 10 IN2- β€” Inverting input of channel 2
Pin 11 PD2 β€” Power-down for channel 2 (active low)
Pin 12 VOCM2 β€” Output common-mode voltage control for channel 2
Pin 13 VEE β€” Negative power supply (or ground)
Pin 14 OUT2+ β€” Non-inverting output of channel 2
Pin 15 OUT2- β€” Inverting output of channel 2
Pin 16 VCC β€” Positive power supply

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for THS4522 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this component. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

THS4522 is suitable for 6 applications: High-Speed ADC Driver, Medical Imaging, Industrial Process Control, Test and Measurement, Portable Battery-Powered Devices, Automotive Sensor Interface.

πŸ”§

High-Speed ADC Driver

The THS4522's fully differential output and 95 MHz bandwidth make it ideal for driving high-speed ADCs. It provides balanced signals that improve common-mode rejection and reduce even-order harmonics, enhancing the ADC's effective resolution. The low noise of 4.6 nV/√Hz ensures minimal signal degradation, while the rail-to-rail output maximizes dynamic range. In a typical circuit, the THS4522 is placed between the analog front-end and the ADC input, with a feedback network setting the gain. The VOCM pin sets the output common-mode voltage to match the ADC's reference, ensuring optimal performance. The low quiescent current of 1.1 mA per channel makes it suitable for multi-channel data acquisition systems where power dissipation is a concern.

πŸ’Š

Medical Imaging

In medical imaging systems such as ultrasound and MRI, the THS4522 provides low-noise amplification of sensor signals. Its 4.6 nV/√Hz input noise and high bandwidth preserve the fidelity of the signals, which is critical for diagnostic accuracy. The low power consumption is advantageous for portable and battery-operated medical devices. The fully differential architecture rejects common-mode interference, improving signal quality in noisy hospital environments. The THS4522 can be used in the analog front-end to condition signals from transducers before digitization. Its rail-to-rail output allows full use of the ADC's input range, maximizing dynamic range. The enable pin can be used for power management in battery-powered devices, extending operational life.

🏭

Industrial Process Control

The THS4522 is well-suited for industrial process control systems that require precise signal conditioning. Its wide supply voltage range (2.5V to 5.5V) allows operation from standard industrial power rails. The negative rail input capability enables interfacing with ground-referenced sensors, simplifying design. The low offset voltage of 0.5 mV ensures accurate measurement of small signals. The device's robust operating temperature range of -40Β°C to +125Β°C makes it suitable for harsh industrial environments. In a typical application, the THS4522 amplifies the output of a bridge sensor or thermocouple before feeding it to an ADC. The fully differential output improves noise immunity in electrically noisy factory settings. The low power consumption reduces heat generation, enhancing reliability.

πŸ”§

Test and Measurement

In test and measurement equipment, the THS4522 provides high-bandwidth, low-distortion signal conditioning. Its 95 MHz bandwidth and 100 V/Β΅s slew rate support fast signal acquisition, while the low noise ensures accurate measurements. The fully differential output is ideal for driving differential inputs of high-speed digitizers. The device's low power consumption is beneficial for portable test instruments. The THS4522 can be used in oscilloscope front-ends, spectrum analyzers, and data acquisition cards. Its rail-to-rail output maximizes the input range of the following ADC, improving measurement resolution. The enable pin allows power-down in battery-operated instruments to conserve energy. The device's small TSSOP-16 package saves board space in compact designs.

πŸ“±

Portable Battery-Powered Devices

The THS4522's very low quiescent current of 1.1 mA per channel makes it ideal for portable, battery-powered devices such as handheld medical monitors, portable audio recorders, and wireless sensors. The low power consumption extends battery life, which is critical for these applications. The device operates from a 2.5V to 5.5V supply, allowing direct operation from a single lithium-ion cell or two alkaline batteries. The rail-to-rail output maximizes signal swing, improving dynamic range in low-voltage systems. The enable pin can be used to shut down the amplifier when not in use, further reducing power consumption. The small TSSOP-16 package is suitable for space-constrained designs.

πŸš—

Automotive Sensor Interface

The THS4522 is suitable for automotive sensor interfaces, such as those used in engine control units and battery management systems. Its wide operating temperature range of -40Β°C to +125Β°C meets automotive requirements. The negative rail input allows interfacing with sensors that have ground-referenced outputs. The low offset voltage and low noise ensure accurate measurement of sensor signals. The device's low power consumption reduces heat generation in the engine compartment. The fully differential output provides good common-mode rejection, which is important in the electrically noisy automotive environment. The THS4522 can be used to condition signals from temperature, pressure, and current sensors before digitization. Its small package is suitable for space-constrained automotive modules.

What is the THS4522?
The THS4522 is a very low-power, dual-channel, fully differential amplifier from Texas Instruments with rail-to-rail output and negative rail input. It operates from 2.5V to 5.5V, has a bandwidth of 95 MHz, and consumes only 1.1 mA per channel. It is designed for low-power data acquisition and high-density applications.
What is the supply voltage range of THS4522?
The THS4522 operates from a supply voltage range of 2.5V to 5.5V. This wide range allows use in both 3.3V and 5V systems. According to the TI datasheet, the device is fully specified for this range, ensuring consistent performance across various power rails.
What is the bandwidth of THS4522?
The THS4522 has a bandwidth of 95 MHz at a gain of 1. This high bandwidth makes it suitable for high-speed signal processing applications such as driving high-speed ADCs and video signal conditioning. The slew rate is 100 V/Β΅s, supporting fast signal transitions.
What is the quiescent current of THS4522?
The THS4522 has a quiescent current of 1.1 mA per channel, totaling 2.2 mA for the dual-channel device. This low power consumption makes it ideal for battery-powered and portable applications where power efficiency is critical. In shutdown mode, the current drops to 0.5 Β΅A.
What is the input voltage noise of THS4522?
The THS4522 has an input voltage noise of 4.6 nV/√Hz. This low noise performance is essential for high-precision applications such as medical imaging and instrumentation, where signal integrity is paramount. The low noise ensures minimal degradation of the signal-to-noise ratio.
What is the difference between THS4522 and THS4552?
The THS4552 is a higher-performance fully differential amplifier with a bandwidth of 150 MHz and lower noise of 3.3 nV/√Hz, while the THS4522 has a bandwidth of 95 MHz and noise of 4.6 nV/√Hz. The THS4552 also has a higher slew rate of 220 V/¡s. Both are pin-compatible in the TSSOP-16 package, but the THS4552 consumes slightly more power.
Can THS4552 replace THS4522?
Yes, the THS4552 can replace the THS4522 in most applications as it is pin-compatible and offers higher bandwidth and lower noise. However, the THS4552 has a higher quiescent current (1.35 mA per channel) and may not be suitable for ultra-low-power designs. Verify the power budget and performance requirements before substitution.
What is the best drop-in replacement for THS4522?
The best drop-in replacement for THS4522 is the THS4552 from Texas Instruments, as it is pin-compatible and offers improved bandwidth and noise. For a lower-power option, the THS4521 (single-channel) or THS4524 (quad-channel) can be considered if the channel count differs. Always verify pinout and specifications.
Where can I buy THS4522?
The THS4522 is available from major distributors such as DigiKey and Mouser. For example, the THS4522IPWR is listed on DigiKey with pricing and availability. You can also purchase directly from TI's website. As of 2026-08-26, the price for 1 unit is approximately $3.42.
What is the price of THS4522?
As of 2026-08-26, the price of THS4522IPWR is approximately $3.42 for 1 unit, $3.08 for 10 units, $2.74 for 100 units, $2.47 for 500 units, and $2.19 for 1000 units. Prices may vary by distributor and quantity.
What is the lead time for THS4522?
The lead time for THS4522 is typically 1-2 weeks for standard orders from distributors like DigiKey and Mouser. However, lead times can vary based on stock levels and demand. Check the distributor's website for real-time availability and lead time information.
Is THS4522 in stock?
As of 2026-08-26, the THS4522IPWR is in stock at DigiKey and Mouser. However, stock levels can change rapidly. It is recommended to check the distributor's website for the most current inventory status.
Where can I download the THS4522 datasheet PDF?
The THS4522 datasheet PDF can be downloaded from the TI website at https://www.ti.com/lit/ds/symlink/ths4522.pdf. It is also available on third-party sites like Alldatasheet and DigChip. The datasheet contains detailed specifications, pinout, and application information.
What are the key specifications of THS4522 that engineers should know?
Engineers should know that the THS4522 is a dual fully differential amplifier with 95 MHz bandwidth, 100 V/¡s slew rate, 4.6 nV/√Hz noise, and 1.1 mA quiescent current per channel. It operates from 2.5V to 5.5V, has rail-to-rail output, and includes a negative rail input. The package is 16-TSSOP.
Is THS4522 suitable for driving ADCs?
Yes, the THS4522 is ideal for driving high-speed ADCs due to its fully differential output, low noise, and high bandwidth. It provides balanced signals that improve ADC performance by reducing common-mode noise and even-order harmonics. The rail-to-rail output maximizes dynamic range.

Engineering reference data for THS4522 β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the THS4522 when you need a dual, very low-power fully differential amplifier with rail-to-rail output and negative rail input. It is ideal for battery-powered and high-density applications where power dissipation is critical. If you need higher bandwidth and lower noise, consider the THS4552, which is pin-compatible but consumes more power. For single-channel applications, the THS4521 offers the same performance in a smaller package. For quad-channel needs, the THS4524 provides four amplifiers in the same TSSOP-16 package. If you require extremely high bandwidth (e.g., >500 MHz), consider the LMH6552 or LTC6400-20, but be prepared for significantly higher power consumption. The ADA4932-2 is a good cross-brand alternative with higher bandwidth but also higher power. Always verify pinout and specifications for your specific application.

Comparison with Alternatives

Parameter This Product THS4552 THS4521 THS4524 LMH6552 ADA4932-2 LTC6400-20
Package 16-TSSOP 16-TSSOP 16-TSSOP 16-TSSOP 16-TSSOP 16-TSSOP 16-TSSOP
Brand Texas Instruments Texas Instruments Texas Instruments Texas Instruments Texas Instruments Analog Devices Analog Devices
Number of Channels 2 2 1 4 1 2 1
Bandwidth 95 MHz 150 MHz 95 MHz 95 MHz 1.5 GHz 560 MHz 2 GHz
Slew Rate 100 V/Β΅s 220 V/Β΅s 100 V/Β΅s 100 V/Β΅s 2400 V/Β΅s 2800 V/Β΅s 3400 V/Β΅s
Input Voltage Noise 4.6 nV/√Hz 3.3 nV/√Hz 4.6 nV/√Hz 4.6 nV/√Hz 0.6 nV/√Hz 3.5 nV/√Hz 0.85 nV/√Hz
Quiescent Current per Channel 1.1 mA 1.35 mA 1.1 mA 1.1 mA 20 mA 9.6 mA 50 mA
Supply Voltage Range 2.5V to 5.5V 2.5V to 5.5V 2.5V to 5.5V 2.5V to 5.5V 4.5V to 12V 3.3V to 10V 2.7V to 5.25V

Key Differentiators

  • Very low power consumption (vs LMH6552)
  • Dual-channel in TSSOP-16 (vs THS4521)
  • Negative rail input (vs ADA4932-2)

Design Notes

The THS4522 operates from 2.5V to 5.5V. Use a low-noise LDO to supply the amplifier to avoid power supply noise coupling into the signal. Place 0.1 Β΅F and 10 Β΅F decoupling capacitors close to the VCC and VEE pins. For single-supply operation, connect VEE to ground and set the output common-mode voltage via the VOCM pin to mid-supply.

For optimal performance, use a solid ground plane and minimize trace lengths for feedback and input connections. Keep the feedback resistors close to the inputs to reduce parasitic capacitance. Use differential routing for the output traces to maintain balance. The exposed pad (if present) should be soldered to the ground plane for thermal and electrical performance.

Ensure the input common-mode voltage does not exceed the specified range. The THS4522 allows the input to go to the negative rail, but not above the positive rail. Also, avoid driving the output beyond the rail-to-rail limits, which can cause distortion. Use precision resistors (1% or better) for the feedback network to maintain gain accuracy.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant per TI product page. Not AEC-Q100 qualified.

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