Microchip Technology

ATSAML21E15B-AUT - 32KB Flash Cortex-M0+ MCU | Microchip

MPN: ATSAML21E15B-AUT ✓ Active
In Stock Ships in 1-3 business days
1.62 V to 3.63 V Vdss < 35 µA/MHz Id 32-pin TQFP (7x7 mm) Package 48 MHz Speed 32 KB (32K x 8) Memory
From $2.98 USD / Unit
MOQ: 1 |
Price updated: 2026-09-21
Volume Pricing
Qty Unit Price Extended
1 $4.62 $4.62
10 $4.16 $41.60
100 $3.71 $371.00
500 $3.35 $1,675.00
1,000 $2.98 $2,980.00
ℹ️ All prices are in USD

ATSAML21E15B-AUT Overview

The Microchip ATSAML21E15B-AUT is an ultra-low-power 32-bit ARM Cortex-M0+ microcontroller from the SAM L21 family, featuring 32KB of Flash, 4KB of SRAM, and a 48 MHz maximum CPU clock speed, housed in a 32-pin TQFP (7x7 mm) package. It targets battery-powered and energy-harvesting applications where both active-mode efficiency (under 35 µA/MHz) and deep-sleep current (200 nA in Sleep mode) are critical design constraints. The integrated Cortex-M0+ core delivers deterministic performance with Thumb-2 instruction set support, while the on-chip peripherals include SERCOM (configurable serial communication), 12-bit ADC, DAC, and op-amps.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, volatile and non-volatile memory, and programmable I/O peripherals. The ARM Cortex-M0+ is an ultra-low-power 32-bit core optimized for embedded systems, widely used in IoT endpoints, wearable electronics, and sensor hubs. Within the SAM L21 family hierarchy, ATSAML21E15B sits between lower-pin-count SAM L10 devices and higher-memory SAM L21G/J variants, balancing I/O count (32-pin TQFP) with low-power features.

Key features of the ATSAML21E15B-AUT include a 12-channel 12-bit ADC with up to 1 MSPS sampling, configurable SERCOM modules that operate as UART, SPI, or I2C, an on-chip temperature sensor, and full-speed USB device support. The integrated Power Management Unit (PMU) enables multiple SleepWalking standby modes that allow peripherals to wake the CPU only on relevant events. The device operates from a 1.62V to 3.63V supply, supporting direct connection to single-cell Li-ion or two AA cells.

Typical applications include wearable fitness trackers, IoT sensor nodes, low-power wireless modules, smart thermostats, and battery-powered industrial sensors. The combination of Cortex-M0+ processing power and sub-microamp Sleep current makes this MCU ideal for designs where battery life spans years rather than weeks. Engineers should leverage the Peripheral Touch Controller and Event System to minimize CPU wake-up events and maximize energy efficiency.

Drop-in alternatives for ATSAML21E15B-AUT — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAML21E15B-AUT (same form factor and footprint) — differing in ADC, Package, Active Current, Core, Flash Memory.

Microchip Technology
ADC: 12-bit
Package: 32-TQFP (7x7 mm)
Active Current: <25 uA/MHz
Compare with ATSAML21E15B-AUT →
Microchip Technology
ADC: 12-bit, 1 MSPS, up to 20 channels
Package: 48-TQFP (7x7 mm)
Active Current: Under 35 µA/MHz
Compare with ATSAML21E15B-AUT →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAML21E16B-AUT

✅ Drop-In
Microchip Technology
📦 32-TQFP (7x7 mm)
ARM Cortex-M0+ (32-bit) · SAM L21E, Functional Safety (FuSa) · 48 MHz · 64 KB (64K x 8) · 8 KB · 1.62 V to 3.63 V · 25 · 32-TQFP (7x7 mm)

✓ In Stock

$2.65 / Unit

View Datasheet →

ATSAML21E15B-MUT

✅ Drop-In
Microchip Technology
📦 32-TQFP (7x7 mm)
ARM Cortex-M0+ · 32-bit · 48 MHz · 32 KB · 4 KB · 1.62 V to 3.63 V · < 35 uA/MHz · 200 nA

✓ In Stock

$2.2 / Unit

View Datasheet →

ATSAML21E15B-ANT

✅ Drop-In
📦 32-TQFP (7x7 mm)
identical die and pinout, NiPdAu lead finish for harsh-environment solderability vs matte tin

📋 Reference alternative (not in catalog)

ATSAML21E17B-AUT

✅ Drop-In
📦 32-TQFP (7x7 mm)
128KB Flash vs 32KB (+300%), 8KB SRAM vs 4KB (+100%), same peripheral set and pinout

📋 Reference alternative (not in catalog)

ATSAML11E15A-AUT

✅ Drop-In
Microchip Technology
📦 32-TQFP (7x7 mm)
ARM Cortex-M23 · 32-bit · 32 MHz · 32 KB (32K x 8) Flash · 8 KB SRAM · 1.62 V to 3.63 V · -40 C to +85 C (Industrial) · 32-TQFP (7x7 mm)

✓ In Stock

$2.07 / Unit

View Datasheet →

ATSAML10E15A-AUT

✅ Drop-In
📦 32-TQFP (7x7 mm)
SAM L10 lower-cost variant, 16KB Flash vs 32KB (-50%), fewer SERCOM instances (4 vs 6)

📋 Reference alternative (not in catalog)

ATSAML21E15B-AUT Maximum Ratings & Electrical Characteristics

Core Architecture ARM Cortex-M0+
Core Bit Width 32-bit
Maximum CPU Clock 48 MHz
Flash Memory 32 KB (32K x 8)
SRAM 4 KB
Package 32-pin TQFP (7x7 mm)
Operating Voltage Range 1.62 V to 3.63 V
Active Mode Current < 35 µA/MHz
Sleep Mode Current 200 nA
ADC 12-bit, up to 1 MSPS
SERCOM Modules 6 (configurable UART/SPI/I2C)
Operating Temperature Range -40 °C to +85 °C (AUT grade)
Mounting Type Surface Mount
MSL Level 3 (168 hours)
RoHS Status Compliant
Lead-Free Yes
AEC-Q100 Qualification Not qualified (AUT grade is industrial extended temperature)

ATSAML21E15B-AUT Pin Configuration

TQFP-32 (7x7mm) Package Pinout Diagram TQFP-32 7x7mm, P0.8mm, JEDEC MS-026. Pin 1 by dot. TQFP-32 (7x7mm) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
Pin 1 PA00 — General purpose I/O / SERCOM1[0]
Pin 2 PA01 — General purpose I/O / SERCOM1[1]
Pin 3 PA02 — General purpose I/O / AIN[0] / VOUT
Pin 4 PA03 — General purpose I/O / AIN[1] / VREFA
Pin 5 GND — Ground
Pin 6 VDD — Digital supply voltage
Pin 7 PA04 — General purpose I/O / SERCOM0[0] / TC0[0]
Pin 8 PA05 — General purpose I/O / SERCOM0[1] / TC0[1]
Pin 9 PA06 — General purpose I/O / SERCOM0[2] / TC1[0]
Pin 10 PA07 — General purpose I/O / SERCOM0[3] / TC1[1]
Pin 11 PA08 — General purpose I/O / SERCOM2[0] / TC2[0]
Pin 12 PA09 — General purpose I/O / SERCOM2[1] / TC2[1]
Pin 13 PA10 — General purpose I/O / SERCOM2[2] / TCC0[0]
Pin 14 PA11 — General purpose I/O / SERCOM2[3] / TCC0[1]
Pin 15 GND — Ground
Pin 16 VDD — Digital supply voltage
Pin 17 PA14 — General purpose I/O / SERCOM4[2] / TCC0[4]
Pin 18 PA15 — General purpose I/O / SERCOM4[3] / TCC0[5]
Pin 19 PA16 — General purpose I/O / SERCOM3[0] / TCC1[0]
Pin 20 PA17 — General purpose I/O / SERCOM3[1] / TCC1[1]
Pin 21 PA18 — General purpose I/O / SERCOM3[2] / TCC1[2]
Pin 22 PA19 — General purpose I/O / SERCOM3[3] / TCC1[3]
Pin 23 PA20 — General purpose I/O / SERCOM5[2] / TCC0[6]
Pin 24 PA21 — General purpose I/O / SERCOM5[3] / TCC0[7]
Pin 25 PA22 — General purpose I/O / SERCOM5[0] / TC4[0]
Pin 26 PA23 — General purpose I/O / SERCOM5[1] / TC4[1]
Pin 27 PA24 — USB_DM / General purpose I/O
Pin 28 PA25 — USB_DP / General purpose I/O
Pin 29 RESET — Reset input, active low
Pin 30 AVDD — Analog supply voltage
Pin 31 GND — Ground
Pin 32 PA27 — General purpose I/O / SERCOM1[3]

Typical Applications

ATSAML21E15B-AUT is suitable for 6 applications: Battery-Powered IoT Sensor Node, Wearable Fitness Tracker, Smart Home Thermostat, Industrial Wireless Sensor Module, USB-Powered Data Logger, Low-Power BLE Beacon.

🧩

Battery-Powered IoT Sensor Node

The ATSAML21E15B-AUT is an ideal main controller for battery-powered IoT sensor nodes transmitting temperature, humidity, or motion data over LoRaWAN, BLE, or Sub-GHz radios. Its 35 µA/MHz active current at 48 MHz and 200 nA Sleep current with full SRAM retention enable multi-year battery life on 2x AA cells or coin-cell batteries when paired with a 1-2% duty cycle. The 6 SERCOM modules allow simultaneous SPI connection to a sensor frontend, I2C bus to a digital sensor, and UART link to a wireless module. The integrated 12-bit ADC and on-chip op-amps can directly interface analog sensors (thermistors, electrochemical gas cells) without external signal conditioning. Engineers should configure SleepWalking peripherals so the ADC or RTC triggers wake-up only on threshold-crossing events, keeping the CPU in Standby mode for 99% of the duty cycle.

📱

Wearable Fitness Tracker

The ATSAML21E15B-AUT suits wearable fitness tracker designs where compact 7x7 mm TQFP footprint, sub-100 µA average system current, and integrated USB device support streamline the bill of materials. The Cortex-M0+ core at 48 MHz runs BLE stack, heart-rate sensor algorithms (PPG), and step-counter firmware concurrently. The integrated 12-bit ADC samples PPG photodiode signals at 100 Hz with DMA-driven SleepWalking, waking the CPU only at every 10th sample for FFT-based heart-rate variability calculation. Full-speed USB device support enables direct charging and data sync without an external USB controller, reducing BOM cost by $0.50-$1.00 versus discrete USB solutions.

🏭

Smart Home Thermostat

The ATSAML21E15B-AUT integrates an ARM Cortex-M0+ core with 32KB Flash, 12-bit ADC, and on-chip op-amps to drive a wall-mounted thermostat's temperature sensing, relay control, and Wi-Fi/BLE link to a home automation hub. Operating from a 24VAC transformer-rectified supply (after an external LDO to 3.3V), the MCU samples thermistor temperature at 1 Hz, runs PID control to drive a relay or 0-10V actuator, and maintains a TFT display. The 6 SERCOM interfaces allow SPI connection to an ESP32 Wi-Fi co-processor, I2C bus to a CO2 sensor and EEPROM, and UART link to the TFT controller. At <35 µA/MHz active, the MCU draws approximately 1.7 mA at 48 MHz - acceptable for line-powered designs where standby current is dominated by the relay coil driver circuit.

🏭

Industrial Wireless Sensor Module

In Industrial IoT (IIoT) wireless sensor modules, the ATSAML21E15B-AUT's wide 1.62-3.63V operating voltage, -40 °C to +85 °C industrial temperature range, and 32KB Flash enable condition monitoring of motors, pumps, and bearings on factory floors. The MCU reads vibration data from an external MEMS accelerometer over SPI, performs on-chip FFT for spectral analysis, and transmits alerts via Sub-GHz wireless (868/915 MHz) when anomaly thresholds are crossed. The integrated 12-bit ADC samples analog 4-20 mA loop signals from legacy industrial sensors without external signal conditioning, while the Event System routes sensor triggers to timer captures without CPU intervention. Engineers can leverage the SAM L21 SleepWalking mode to run vibration sampling for 100 ms every 10 minutes while maintaining average current under 50 µA - sufficient for 5+ year battery life on industrial-grade lithium cells.

🖥️

USB-Powered Data Logger

USB-powered data loggers for environmental monitoring, medical diagnostics, or asset tracking benefit from the ATSAML21E15B-AUT's integrated full-speed USB device controller, 32KB Flash for firmware, and on-chip 12-bit ADC. The MCU presents as a USB CDC virtual COM port to the host PC, enabling real-time data streaming and configuration via standard serial terminal applications. The integrated 3.3V LDO (when sourced from VBUS through a 5V-to-3.3V regulator) can supply 50 mA to external sensors, eliminating the need for a separate power management IC. With 32KB Flash and 4KB SRAM, the firmware can buffer 2000+ 12-bit ADC samples in RAM for high-speed burst logging to host. Operating at 48 MHz, the MCU consumes approximately 1.7 mA active - within USB 2.0 bus-powered device limits (100 mA unit load).

📱

Low-Power BLE Beacon

BLE beacon designs for asset tracking, indoor positioning, or retail proximity marketing benefit from the ATSAML21E15B-AUT's 200 nA Sleep current and Cortex-M0+ efficiency, even when paired with an external BLE module. The MCU wakes from Sleep every 100-1000 ms to update beacon payload data (sensor readings, battery voltage) and triggers a BLE advertisement burst via a GPIO pulse to the BLE module's TX_EN pin, then immediately returns to Sleep. Average system current stays under 20 µA - achieving 6+ months of battery life on a CR2032 coin cell. The 32KB Flash accommodates custom beacon firmware (iBeacon, Eddystone, or proprietary formats), and 4KB SRAM buffers the advertisement packet assembly without external memory.

Recommended Products Summary

RN2483 LoRaWAN transceiver module for long-range uplink Used in: Battery-Powered IoT Sensor Node BME280 I2C temperature/humidity/pressure sensor Used in: Battery-Powered IoT Sensor Node ATSAML21E15B-AUT Microchip Technology Used in: Battery-Powered IoT Sensor Node, Wearable Fitness Tracker, Smart Home Thermostat, Industrial Wireless Sensor Module, USB-Powered Data Logger, Low-Power BLE Beacon MAX30102 PPG heart-rate and SpO2 sensor Used in: Wearable Fitness Tracker LIS2DH 3-axis accelerometer for step counting Used in: Wearable Fitness Tracker ESP32-WROOM-32 Wi-Fi/BLE co-processor for cloud connectivity Used in: Smart Home Thermostat MCP9700 Analog temperature sensor with 10 mV/°C output Used in: Smart Home Thermostat ADXL345 3-axis MEMS accelerometer for vibration sensing Used in: Industrial Wireless Sensor Module CC1101 Sub-GHz wireless transceiver for industrial telemetry Used in: Industrial Wireless Sensor Module MCP3421 18-bit I2C ADC for precision analog measurements Used in: USB-Powered Data Logger AT25SF081 8MB SPI Flash for local data buffering Used in: USB-Powered Data Logger BMD-340 BLE 5.0 module with UART control interface Used in: Low-Power BLE Beacon CR2032 Primary lithium coin cell, 240 mAh capacity Used in: Low-Power BLE Beacon
What is the Flash memory size of ATSAML21E15B-AUT?
The ATSAML21E15B-AUT integrates 32 KB of on-chip Flash (32K x 8) for program storage, alongside 4 KB of SRAM for data. According to the Microchip product page, this places the device in the lower-density tier of the SAM L21 family, suitable for code footprints under 24 KB after bootloader overhead. Engineers targeting larger firmware images should consider the ATSAML21E16B (64 KB Flash) or ATSAML21E17B (128 KB Flash) variants in the same 32-pin TQFP package.
What is the operating voltage range of ATSAML21E15B-AUT?
The ATSAML21E15B-AUT operates from 1.62 V to 3.63 V supply voltage, covering single-cell Li-ion (3.0-4.2 V with LDO) and 2x AA alkaline (2.0-3.2 V direct) battery chemistries. The Microchip datasheet specifies a core voltage regulator that maintains stable CPU performance across this range, with brown-out detector thresholds programmable through the Supply Controller (SUPC). For 5V systems, an external LDO is required.
How much active current does the ATSAML21E15B-AUT consume?
The ATSAML21E15B-AUT consumes under 35 µA/MHz in active mode when running from the internal 48 MHz oscillator, and 200 nA in Sleep mode with full SRAM retention and RTC running. According to Microchip benchmarks, this enables battery lifetimes exceeding 5 years on a single CR2032 coin cell for typical IoT sensor duty cycles (1% active, 99% Sleep). The SleepWalking peripheral event system allows the CPU to remain asleep until a configured sensor threshold is crossed.
Where can I buy ATSAML21E15B-AUT at the best price?
The ATSAML21E15B-AUT is in stock at DigiKey, Mouser, Arrow, and LCSC as of 2026-09-22. Pricing ranges from $4.62 at qty-1 down to $2.98 at qty-1000 from major distributors. LCSC offers competitive pricing at $1.1730 for the lowest tier, appealing for high-volume consumer designs. For automotive-grade replacements, the -MUT suffix variant (AEC-Q100 qualified) is available in the same 32-TQFP package.
What is the lead time for ATSAML21E15B-AUT orders?
Lead time for ATSAML21E15B-AUT at DigiKey and Mouser is currently 8-12 weeks for factory-direct orders as of 2026-09-22, with distributor stock available for immediate shipment in reels of 250 or 2000 units. The Microchip factory is allocating production through Q4 2026 due to strong industrial IoT demand. For urgent prototype needs, LCSC typically maintains 3000-5000 unit reel inventory with same-week shipping.
ATSAML21E15B-AUT vs ATSAML21E16B-AUT - which should I choose?
Choose the ATSAML21E15B-AUT when your compiled firmware fits within 24 KB of Flash after bootloader and library overhead, as it offers the lowest cost at $4.62 qty-1. Choose the ATSAML21E16B-AUT (64 KB Flash) when you need additional headroom for over-the-air (OTA) update staging buffers or feature-rich application stacks. Both share the same 32-pin TQFP (7x7 mm) package and identical peripheral set, making them drop-in compatible on existing PCBs.
What is the difference between ATSAML21E15B-AUT and ATSAML21E15B-MUT?
The ATSAML21E15B-AUT is rated for -40 °C to +85 °C industrial extended temperature, while the ATSAML21E15B-MUT variant carries AEC-Q100 automotive qualification and -40 °C to +125 °C operating range. Both share identical 32 KB Flash, Cortex-M0+ core at 48 MHz, and 32-TQFP package, making them drop-in compatible. Choose -MUT for automotive ECUs, body controllers, or under-hood applications; choose -AUT for industrial IoT gateways and consumer electronics.
When should I choose ATSAML21E15B-AUT over an STM32L0 competitor?
Choose the ATSAML21E15B-AUT when you need Microchip's ecosystem (MPLAB X IDE, Harmony 3 framework), tighter Cortex-M0+ integration with on-chip op-amps and DAC, or pin-to-pin compatibility with the rest of the SAM L21 family for scalable designs. Choose STM32L0 when you require STM32Cube ecosystem familiarity, broader third-party middleware support, or Cortex-M0+ variants with larger Flash (up to 192 KB). Both families target similar sub-35 µA/MHz active power envelopes.
What is the best drop-in replacement for ATSAML21E15B-AUT?
The best drop-in replacement for ATSAML21E15B-AUT is the ATSAML21E16B-AUT from the same SAM L21 family in the identical 32-pin TQFP (7x7 mm) package, offering 64 KB Flash versus 32 KB. For automotive migration, the ATSAML21E15B-MUT provides identical silicon in AEC-Q100 qualified form. The -ANT suffix variant (NiPdAu lead finish) is a packaging-only drop-in for harsh-environment solderability requirements. All three alternatives share the same pinout, peripheral map, and Cortex-M0+ core.
Where can I download the ATSAML21E15B-AUT datasheet PDF?
The official ATSAML21E15B datasheet PDF is available from Microchip at https://www.microchip.com/en-us/product/atsaml21e15b - click the 'Documentation' tab to access the 400+ page family datasheet covering all SAM L21 package variants, electrical characteristics, and peripheral register maps. The datasheet also includes reference schematics, PCB layout guidelines for the 32-TQFP package, and Migration Guide section for moving designs between SAM L10/L11/L21 families.
Where do I find the ATSAML21E15B-AUT pinout diagram?
The ATSAML21E15B-AUT 32-pin TQFP pinout is documented in the Microchip SAM L21 family datasheet, Section 'Pinout' (typically pages 12-18). The package_svg_key 'tqfp-32' on XAIPART renders the same pinout interactively, showing pin 1 at top-left, with PA00-PA27 port pins, VDD, GND, AVDD, and RESET distributed across the 7x7 mm TQFP footprint. Engineers should cross-reference the multiplexing table to assign SERCOM, ADC, and timer functions to physical pins.
Does ATSAML21E15B-AUT support USB?
The ATSAML21E15B-AUT includes a full-speed USB 2.0 device controller with on-chip transceiver, supporting 12 Mbps data rate and up to 8 endpoints. According to the Microchip datasheet, the USB D+/D- pins share physical package pins with PA24/PA25 and require an external 1.5 kohm pull-up on D+ to 3.3V. For USB bus-powered designs, the integrated 3.3V LDO can supply 50 mA to external circuitry, eliminating the need for a separate voltage regulator.
Is the ATSAML21E15B-AUT RoHS compliant?
Yes, the ATSAML21E15B-AUT is fully RoHS compliant (EU Directive 2011/65/EU and amendment 2015/863), lead-free (Pb-free) with matte tin (Sn) lead finish, and uses halogen-free mold compound. The Microchip material declaration sheet confirms REACH SVHC compliance and conflict-mineral sourcing through the Responsible Minerals Assurance Process (RMAP). MSL Level 3 moisture sensitivity rating requires JEDEC J-STD-033 floor-life baking (125 °C, 24 hours) if the sealed bag is opened more than 168 hours before reflow.
What development tools support the ATSAML21E15B-AUT?
The ATSAML21E15B-AUT is fully supported by Microchip's MPLAB X IDE (version 6.10 or later), MPLAB XC32 C/C++ compiler, and Harmony 3 software framework. Hardware tools include the ATSAMHA1E15A-XPRO (Xplained Pro evaluation board, $49) with on-board debugger, the ATSAML21-XPRO-B (base board for custom expansion), and the Atmel-ICE programmer/debugger. Third-party IDEs (IAR Embedded Workbench, Keil MDK) also support this device via Microchip's CMSIS-Pack.
What is the junction temperature and thermal performance of ATSAML21E15B-AUT?
The ATSAML21E15B-AUT in 32-pin TQFP (7x7 mm) package has a junction-to-ambient thermal resistance (theta_JA) of approximately 70 °C/W on a standard JEDEC 4-layer test board. At maximum active power dissipation of 14 mW (3.3V × 4.2 mA at 48 MHz), the junction temperature rise is only 1 °C above ambient - well within the -40 °C to +85 °C operating range. The exposed thermal pad is not present on this 32-pin TQFP variant, so no PCB thermal pad connection is required.

Engineering reference data for ATSAML21E15B-AUT — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAML21E15B-AUT when designing cost-optimized IoT sensor nodes, wearable devices, or USB peripherals where firmware fits within 24 KB Flash and industrial extended temperature (-40 °C to +85 °C) is sufficient. The integrated USB 2.0 device controller eliminates the need for an external USB interface IC in data logger designs, saving $0.50-$1.00 BOM cost. Migrate to ATSAML21E16B-AUT when OTA staging or feature expansion pushes firmware beyond 24 KB, or to ATSAML21E15B-MUT for AEC-Q100 automotive applications requiring 125 °C operation. For TrustZone-M secure boot requirements, choose ATSAML11E15A-AUT instead. The 6 SERCOM instances make this MCU ideal for designs with multiple communication buses (sensor I2C + wireless SPI + debug UART) without peripheral conflicts.

Comparison with Alternatives

Parameter This Product ATSAML21E16B-AUT ATSAML21E15B-MUT ATSAML21E15B-ANT ATSAML21E17B-AUT ATSAML11E15A-AUT ATSAML10E15A-AUT
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 32-TQFP (7x7 mm) 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same
Flash Memory 32 KB 64 KB 32 KB 32 KB 128 KB 16 KB 16 KB
SRAM 4 KB 8 KB 4 KB 4 KB 8 KB 4 KB 4 KB
Operating Temperature -40 °C to +85 °C -40 °C to +85 °C -40 °C to +125 °C (AEC-Q100) -40 °C to +85 °C -40 °C to +85 °C -40 °C to +85 °C -40 °C to +85 °C
SERCOM Instances 6 6 6 6 6 6 4
TrustZone-M Security No No No No No Yes No
AEC-Q100 Qualified No (AUT grade) No Yes No No No No

Key Differentiators

  • Lowest-cost SAM L21 variant with full USB 2.0 device support (vs ATSAML21E16B-AUT)
  • Industrial extended temperature, not automotive qualified (vs ATSAML21E15B-MUT)
  • Higher SERCOM count than SAM L10 family (vs ATSAML10E15A-AUT)

Design Notes

Decouple VDD and AVDD separately with 100 nF X7R ceramic capacitors placed within 3 mm of each supply pin, plus a 4.7 µF bulk capacitor on VDD. The SAM L21 internal 1.2V core LDO is supplied from VDD and requires bulk capacitance to maintain regulation during Sleep-Wake transitions. According to the Microchip datasheet, AVDD (analog supply) must be decoupled from VDD through a ferrite bead or 10 Ω resistor when ADC accuracy below 1 LSB is required - bypassing AVDD directly to VDD introduces digital switching noise into the ADC reference.

Do not leave unused SERCOM pins floating when the SERCOM module is enabled - configure them as GPIO outputs driven low in the PORT register to avoid parasitic current draw (typically 5-20 µA per floating pin). The SAM L21 datasheet specifies that pins configured as analog inputs (AIN) require explicit PORT->Group[port].PINCFG[n].INEN = 0 setting to disable the digital input buffer, otherwise input leakage current exceeds 1 µA per pin. When migrating from SAM L10/L11 designs, verify that SERCOM channel-to-pin mapping matches - the L21 family uses a different peripheral multiplexing scheme.

For 32-pin TQFP (7x7 mm) PCB layout, route all GPIO and SERCOM traces on the top layer with continuous reference plane on layer 2. Maintain 50 Ω characteristic impedance for USB D+/D- differential pair with 90 Ω differential impedance, using 0.20 mm trace width and 0.15 mm spacing on 0.20 mm dielectric. Place the 12 MHz crystal (or 32.768 kHz crystal for RTC) within 5 mm of XIN/XOUT pins with grounded guard ring. The Microchip SAM L21 hardware design checklist recommends 4-layer stackup (signal-GND-power-signal) for designs with USB or high-speed SERCOM.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

AUT suffix indicates industrial extended temperature grade, not automotive. RoHS compliant per Microchip material declaration. AEC-Q100 qualified variants available with -MUT suffix. MSL Level 3 (168 hours floor life) per JEDEC J-STD-020.

Data verified on: 2026-09-22 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology ATSAML21E15B-AUT ATSAML21E16B-AUT ATSAML21E15B-MUT ATSAML21E15B-ANT ATSAML21E17B-AUT ATSAML11E15A-AUT ATSAML10E15A-AUT ARM Cortex-M0+ microcontroller MCU SAM L21 family TQFP-32 TQFP package USB 2.0 device SERCOM ADC 12-bit RoHS AEC-Q100 MPLAB X IDE Harmony 3 framework JEDEC J-STD-033 low-power Sleep mode IoT sensor node wearable fitness tracker
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