Microchip Technology

PIC18F2221-I/SS - 8-Bit 40MHz 4KB Flash MCU 28-SSOP | Microchip

MPN: PIC18F2221-I/SS ✓ Active
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4.2 V to 5.5 V Vdss 28-SSOP (0.209 inch / 5.30 mm body width) Package 40 MHz (16 MIPS) Speed 4 KB (2K x 16 words) Memory
From $2.79 USD / Unit
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Price updated: 2026-09-26
Volume Pricing
Qty Unit Price Extended
1 $4.52 $4.52
10 $4.07 $40.70
100 $3.61 $361.00
500 $3.16 $1,580.00
1,000 $2.79 $2,790.00
ℹ️ All prices are in USD

PIC18F2221-I/SS Overview

The Microchip Technology PIC18F2221-I/SS is an 8-bit PIC18 enhanced Flash microcontroller built on a RISC architecture, delivering up to 40 MHz / 16 MIPS throughput and integrating 4KB (2K x 16) of self-programming Flash program memory in a 28-pin SSOP (Shrink Small Outline Package). It is qualified to the industrial -40C to +85C operating range (denoted by the -I suffix) and targets 5V systems requiring nanoWatt power management.

An 8-bit PIC microcontroller is a Harvard-architecture RISC CPU designed for deterministic, low-power embedded control. Within the broader taxonomy, PIC18 sits above baseline PIC10/12/16 parts and below 16-bit dsPIC/PIC24 and 32-bit PIC32 devices. The PIC18 family adds 16-bit instructions, a hardware multiplier, linear RAM access up to 4KB and C-compiler friendly addressing, making it a workhorse for cost-sensitive real-time control applications.

Key features of the PIC18F2221-I/SS include 256 bytes of EEPROM, 512 bytes of SRAM, 25 digital I/O pins, 13 channels of 10-bit Analog-to-Digital conversion, two analog comparators, two Capture/Compare/PWM modules, a Master Synchronous Serial Port configurable as SPI or I2C, an ICD (In-Circuit Debug) interface and nanoWatt technology with multiple power-managed modes including Idle, Sleep and peripheral gating.

Technically, the PIC18F2221 combines a hardware multiplier, 8x8 hardware multiply in a single cycle and 31-level stack with 200ns instruction execution at 20 MHz (40 MHz oscillator input via 4x PLL or external). The 10-bit ADC supports up to 13 analog input channels with acquisition time programmable via software, and the MSSP peripheral provides both SPI and I2C master/slave modes. The nanoWatt power-managed modes enable typical sleep currents in the microamp range, suitable for battery-backed designs.

Typical applications for the PIC18F2221-I/SS include low-cost consumer appliances, white-goods control boards, HVAC sensor interfacing, battery chargers, security alarm panels, motor control (small DC/BLDC via PWM and comparator) and industrial sensor hubs where 5V I/O and IEC 61010-1 isolation-friendly logic levels are required.

When designing with the PIC18F2221-I/SS, allocate a minimum 0.1uF decoupling capacitor adjacent to each VDD/VSS pair and follow Microchip's Emulation/ICD connection guidelines if you intend to use the on-chip debug hardware. Devices with the same flash size but different pin count exist (PIC18F2221 = 28-pin, PIC18F4321 = 44-pin); always match the package to the PCB footprint before sourcing.

Drop-in alternatives for PIC18F2221-I/SS — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F2221-I/SS (same form factor and footprint) — differing in Operating Temperature, Package, Program Memory (Flash), Supply Voltage (VDD), ADC.

Microchip Technology
Operating Temperature: -40 °C to +85 °C (industrial)
Package: 28-pin SSOP (Shrink Small Outline Package)
Program Memory (Flash): 8 KB (4K x 16 words)
Microchip Technology
Operating Temperature: -40C to +85C (Industrial)
Package: SSOP-28 (208 mil)
Program Memory (Flash): 4 KB (2K x 16)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F2221-I/SO

✅ Drop-In ⚠️ Specs Unverified
📦 28-SOIC (0.300 inch body width)
Same 28-pin SOIC package; body width 7.50 mm vs 5.30 mm SSOP - drop-in electrically but different PCB footprint

📋 Reference alternative (not in catalog)

PIC18F2321-I/SS

✅ Drop-In
Microchip Technology
📦 28-SSOP
PIC18 8-bit RISC · 77 single-word instructions · 40 MHz · 10 MIPS (200 ns instruction cycle) · 8 KB (4K x 16 words) · 512 bytes · 256 bytes · 4.2 V to 5.5 V

✓ In Stock

$2.05 / Unit

View Datasheet →

PIC18F2420-I/SS

✅ Drop-In
📦 28-SSOP
16KB Flash vs 4KB (+300%), 10-bit ADC and identical peripherals in 28-SSOP

📋 Reference alternative (not in catalog)

PIC18F2520-I/SS

✅ Drop-In
📦 28-SSOP
32KB Flash and 1KB EEPROM vs 4KB/256B (+700% Flash, +300% EEPROM), same 28-SSOP

📋 Reference alternative (not in catalog)

PIC18F2221-E/SS

✅ Drop-In
📦 28-SSOP
Same die, extended -40C to +125C vs -40C to +85C industrial range; same SSOP-28

📋 Reference alternative (not in catalog)

PIC18F2221T-I/SS

✅ Drop-In ⚠️ Specs Unverified
📦 28-SSOP
Same die, T = Tape & Reel packaging code; identical 28-SSOP, no electrical difference

📋 Reference alternative (not in catalog)

PIC18LF2221-I/SS

✅ Drop-In
Microchip Technology
📦 28-SSOP
PIC18 8-bit RISC · 4 KB (2K x 16) · 512 bytes · 256 bytes · 40 MHz (10 MIPS) · 2.0 V to 5.5 V · 25 · 10-bit, multiple channels

✓ In Stock

$2.02 / Unit

View Datasheet →

PIC18F2221-I/SS Maximum Ratings & Electrical Characteristics

Product Type 8-bit Microcontroller (MCU)
Architecture PIC18 (Harvard RISC)
Family PIC18F2xx1/4xx1 Enhanced Flash with nanoWatt
Core / Data Bus Width 8-bit
Maximum CPU Speed 40 MHz (16 MIPS)
Instruction Cycle Time 200 ns at 20 MHz / 100 ns at 40 MHz
Program Memory (Flash) 4 KB (2K x 16 words)
Data EEPROM 256 bytes
Data SRAM 512 bytes
I/O Pins 25
ADC 10-bit, 13 channels
Comparators 2
CCP/ECCP Modules 2 CCP
Serial Interfaces 1x MSSP (SPI / I2C), AUSART
Supply Voltage (VDD) 4.2 V to 5.5 V
Operating Temperature -40C to +85C (Industrial, -I suffix)
Package 28-SSOP (0.209 inch / 5.30 mm body width)
Mounting Type Surface Mount
RoHS Status Compliant
On-Chip Debug ICD (In-Circuit Debugger)
Program Memory Type Flash (self-programming)

PIC18F2221-I/SS Pin Configuration

SSOP-28 Package Pinout Diagram SSOP-28 5.3x10.2mm, P0.65mm, JEDEC MO-150. 1 28 2 27 3 26 4 25 5 24 6 23 7 22 8 21 9 20 10 19 11 18 12 17 13 16 14 15 SSOP-28
Pin 1 RA0/AN0 — PORTA bit 0 / Analog input channel 0
Pin 2 RA1/AN1 — PORTA bit 1 / Analog input channel 1
Pin 3 RA2/AN2/VREF-/CVREF — PORTA bit 2 / Analog input 2 / VREF- / Comparator VREF output
Pin 4 RA3/AN3/VREF+ — PORTA bit 3 / Analog input 3 / VREF+
Pin 5 RA4/T0CKI/C1OUT — PORTA bit 4 / Timer0 clock input / Comparator 1 output
Pin 6 RA5/AN4/SS/HLVDIN/C2OUT — PORTA bit 5 / Analog input 4 / SSP slave select / High/Low-Voltage detect / Comparator 2 output
Pin 7 VSS — Ground reference
Pin 8 OSC1/CLKI/RA7 — Oscillator input / External clock input / PORTA bit 7
Pin 9 OSC2/CLKO/RA6 — Oscillator output / Clock output / PORTA bit 6
Pin 10 RC0/T1OSO/T1CKI — PORTC bit 0 / Timer1 oscillator output / Timer1 clock input
Pin 11 RC1/T1OSI/CCP2 — PORTC bit 1 / Timer1 oscillator input / CCP2 I/O
Pin 12 RC2/CCP1 — PORTC bit 2 / CCP1 I/O
Pin 13 RC3/SCK/SCL — PORTC bit 3 / SSP SPI clock / I2C clock
Pin 14 RC4/SDI/SDA — PORTC bit 4 / SSP SPI data in / I2C data
Pin 15 RC5/SDO — PORTC bit 5 / SSP SPI data out
Pin 16 RC6/TX/CK — PORTC bit 6 / AUSART TX / AUSART clock
Pin 17 RC7/RX/DT — PORTC bit 7 / AUSART RX / AUSART data
Pin 18 VSS — Ground reference
Pin 19 VDD — Positive supply (4.2 V to 5.5 V)
Pin 20 RB0/AN12/INT0 — PORTB bit 0 / Analog input 12 / External interrupt 0
Pin 21 RB1/AN10/INT1 — PORTB bit 1 / Analog input 10 / External interrupt 1
Pin 22 RB2/AN8/INT2 — PORTB bit 2 / Analog input 8 / External interrupt 2
Pin 23 RB3/AN9/CCP2 — PORTB bit 3 / Analog input 9 / CCP2 I/O
Pin 24 RB4/AN11/KBI0 — PORTB bit 4 / Analog input 11 / Keyboard interrupt 0
Pin 25 RB5/KBI1/PGM — PORTB bit 5 / Keyboard interrupt 1 / LVP programming
Pin 26 RB6/KBI2/PGC — PORTB bit 6 / Keyboard interrupt 2 / ICD clock
Pin 27 RB7/KBI3/PGD — PORTB bit 7 / Keyboard interrupt 3 / ICD data
Pin 28 VDD — Positive supply (4.2 V to 5.5 V)

Typical Applications

PIC18F2221-I/SS is suitable for 6 applications: White Goods and Home Appliance Control, HVAC and Building Automation Sensors, Industrial Sensor Hubs and IoT Gateways, Battery Chargers and Power Tools, Security and Alarm Panels, Small DC/BLDC Motor Control.

🏭

White Goods and Home Appliance Control

The PIC18F2221-I/SS is widely deployed in washing machines, dishwashers, refrigerators and microwave ovens where 5V digital I/O and 28-pin SSOP integration are standard. Its 25 digital I/O pins support keypad scanning, relay drivers, triac firing, buzzer PWM and segment-LCD control via external drivers; the 13-channel 10-bit ADC reads temperature sensors (NTC/PTC), water-level probes and humidity sensors. The PIC18 core executes household real-time control loops deterministically at 40 MHz / 16 MIPS, while nanoWatt sleep currents extend standby power budgets to <2 mW per board to meet Energy Star. The 4KB Flash holds typical appliance state machines and safety interlock firmware; the 256-byte EEPROM retains user preferences and fault logs across power cycles.

🌐

HVAC and Building Automation Sensors

In HVAC wall thermostats, indoor air-quality stations and variable-air-volume controllers, the PIC18F2221-I/SS acts as the central node that digitizes thermistor inputs, CO2/VOC sensor analog channels and occupancy-detector outputs while driving triac-controlled fan stages and communicating over RS-485 or I2C. The 13-channel 10-bit ADC provides 0.5C temperature resolution with proper averaging, and the 256-byte EEPROM stores calibration constants. The MSSP module can be configured as I2C master to scan sensor backbones; nanoWatt idle/sleep modes reduce average supply current to <100 uA for battery-backed wireless sensor variants. The 28-SSOP package suits compact wall-plate enclosures with vertical mounting.

🏭

Industrial Sensor Hubs and IoT Gateways

The PIC18F2221-I/SS is suitable for low-cost industrial 4-20 mA / 0-10 V sensor hubs that aggregate analog inputs from a few field sensors and forward data via RS-485 or Modbus RTU to a PLC. The PIC18 RISC core delivers deterministic 100 ns instruction timing required for tight sensor sampling loops, while 13 ADC channels support a typical 8-sensor scan plus 5 housekeeping inputs. The AUSART module implements Modbus RTU slave without DMA load, and the 256-byte EEPROM retains Modbus address and calibration across maintenance. The 28-SSOP package supports dense PCB layouts where mechanical footprint is constrained; the -40C to +85C industrial grade supports cabinet or panel-mount environments.

⚡

Battery Chargers and Power Tools

Cordless-drill and Li-ion battery charger designs use the PIC18F2221-I/SS to perform CC/CV charge algorithms, monitor cell voltage via the 10-bit ADC, drive MOSFET half-bridges via the two CCP PWM channels, and signal LED status through the digital I/O. The 4KB Flash holds typical NiMH, Li-ion and lead-acid charge profiles; the 256-byte EEPROM saves battery cycle count and pack health data. nanoWatt sleep currents minimize standby drain on the battery pack, and the 40 MHz CPU allows synchronous current-mode control loop execution within a few microseconds. The 28-SSOP package fits inside charger base enclosures with the MCU and analog front-end on a single PCB.

🎥

Security and Alarm Panels

PIC18F2221-I/SS-based security panels implement PIR motion detector scanning via ADC, magnetic-contact zone monitoring on digital I/O, piezo-buzzer alarm drive via PWM and key-fob signal decoding on the AUSART or external interrupt. The 25 I/O pins support 8 zones plus a 4x4 keypad matrix and strobe/LED drivers, while 256 bytes EEPROM stores installer configuration and event logs across power failures. The PIC18 deterministic interrupt response (<100 ns) ensures no missed events even during busy serial housekeeping. The 28-SSOP package suits slim wall-mounted enclosures; nanoWatt sleep mode extends battery backup life to >5 years in typical alarm duty cycles.

🔧

Small DC/BLDC Motor Control

Small BLDC or DC motor controllers for fans, pumps and toys use the PIC18F2221-I/SS to generate complementary PWM via the two CCP channels, drive MOSFET gate signals on the digital I/O, read back-EMF or shunt current via the 10-bit ADC, and implement closed-loop speed control. The 40 MHz / 16 MIPS throughput allows 20 kHz PWM with full PID loop closure inside each commutation period. The 13 ADC channels read motor phase currents, DC bus voltage and PCB temperature; the MSSP SPI drives optional digital potentiometer or gate-driver fault monitoring. The 28-SSOP package fits inside the motor housing or controller base, and nanoWatt sleep enables standby current <1 mA.

Recommended Products Summary

PIC18F2321-I/SS Microchip Technology Used in: White Goods and Home Appliance Control, Industrial Sensor Hubs and IoT Gateways, Security and Alarm Panels PIC18F2520-I/SS 32KB Flash drop-in for firmware with bootloader and OTA Used in: White Goods and Home Appliance Control, Small DC/BLDC Motor Control MCP1700-3302E 3.3V LDO regulator for auxiliary analog rail Used in: White Goods and Home Appliance Control MCP23S08 SPI I/O expander for additional keypad/segment drive lines Used in: White Goods and Home Appliance Control PIC18F2420-I/SS 16KB Flash upgrade with same peripherals for richer HVAC firmware Used in: HVAC and Building Automation Sensors, Battery Chargers and Power Tools MCP9808 High-accuracy I2C temperature sensor for precision thermostats Used in: HVAC and Building Automation Sensors, Security and Alarm Panels MCP2515 Standalone CAN controller for industrial HVAC buses Used in: HVAC and Building Automation Sensors MCP1702 Low-Iq LDO regulator for 5V sensor rails from 24V bus Used in: HVAC and Building Automation Sensors MCP2551 CAN transceiver for industrial fieldbus Used in: Industrial Sensor Hubs and IoT Gateways MAX31865 RTD-to-digital converter for PT100/PT1000 temperature sensing Used in: Industrial Sensor Hubs and IoT Gateways MCP23017 I2C 16-bit I/O expander for additional digital I/O channels Used in: Industrial Sensor Hubs and IoT Gateways MCP73123 Li-ion charge management companion IC Used in: Battery Chargers and Power Tools MCP6002 Low-power op-amp for current-sense amplification Used in: Battery Chargers and Power Tools, Small DC/BLDC Motor Control MCP1700 Low-Iq LDO for MCU rail in battery-powered designs Used in: Battery Chargers and Power Tools, Small DC/BLDC Motor Control PIC18F2221-E/SS Extended -40C to +125C grade for outdoor-ruggedized panels Used in: Security and Alarm Panels MCP2120 IrDA infrared encoder/decoder for key-fob receiver Used in: Security and Alarm Panels MCP8024 3-phase BLDC gate driver companion IC Used in: Small DC/BLDC Motor Control
What is the operating voltage of PIC18F2221-I/SS?
The PIC18F2221-I/SS operates from 4.2V to 5.5V on VDD, designed for nominal 5V systems per the PIC18F2221/4221/2321/4321 datasheet family. The internal core logic derives 3.3V via on-chip regulators, and a stable bulk decoupling capacitor of at least 0.1uF adjacent to each VDD/VSS pair is required to maintain ADC accuracy and minimize VDD droop during transient load events.
How much Flash program memory does the PIC18F2221-I/SS have?
The PIC18F2221-I/SS integrates 4KB of self-programming Flash program memory organized as 2K x 16 words, with 256 bytes of data EEPROM and 512 bytes of SRAM for variables and stack operations. The Flash is rated for a minimum of 100,000 erase/write cycles and supports in-application self-programming under firmware control, allowing bootloader and field-update designs.
What is the maximum CPU clock speed of PIC18F2221-I/SS?
The PIC18F2221-I/SS runs at up to 40 MHz oscillator input, delivering 16 MIPS throughput with a 100 ns instruction cycle. This is achieved either via a 40 MHz external clock or an external 10 MHz crystal feeding the internal 4x PLL. At 5V VDD, this speed is supported across the entire -40C to +85C industrial temperature range.
How many ADC channels does the PIC18F2221-I/SS have?
The PIC18F2221-I/SS includes a 10-bit Analog-to-Digital converter with 13 input channels multiplexed to the available 28-pin package pins. The ADC supports both single-ended and differential conversions (channel-dependent) and provides programmable acquisition time. Reference voltages can be VDD, VSS, or the dedicated VREF+ / VREF- package pins for ratiometric or absolute measurements.
What package does the PIC18F2221-I/SS ship in?
The PIC18F2221-I/SS is housed in a 28-pin Shrink Small Outline Package (SSOP-28) with 0.65 mm pin pitch and a 5.30 mm body width (0.209 inch), designated by the -I/SS suffix in the part number. The SSOP footprint is footprint-compatible with PIC18F2420, PIC18F2520, PIC18F2620, PIC18F2221, PIC18F4221, PIC18F4321 and other PIC18F 28-pin variants, easing PCB reuse.
Where can I buy PIC18F2221-I/SS and what is the current price?
The PIC18F2221-I/SS is in active production and stocked in quantity at major distributors including DigiKey (1212524), Mouser, LCSC (C184393), Avaq and Microchip USA. Pricing as of 2026-09-26 starts around $1.97 per unit at LCSC for cut-tape quantities and rises to approximately $4.52 at qty-1 from DigiKey. Volume breaks at qty 100/500/1000 are typically 20-40% lower than qty-1 pricing.
What is the lead time for PIC18F2221-I/SS in 2026?
Lead time for the PIC18F2221-I/SS as of 2026-09-26 is in stock at DigiKey, Mouser, LCSC and Microchip USA, with most distributors offering same-day or next-day shipping for quantities below 1,000 pieces. For volume orders above 5,000 pieces, lead time can extend to 4-8 weeks depending on whether the part ships from factory stock or scheduled production batches.
Is PIC18F2221-I/SS RoHS compliant?
Yes, the PIC18F2221-I/SS is RoHS compliant per Microchip's product declaration and is supplied in a lead-free matte-tin finish suitable for reflow soldering at peak temperatures up to 260C (JEDEC J-STD-020). The 28-SSOP package is halogen-free and complies with REACH SVHC requirements. The -I industrial temperature suffix also confirms it is the lead-free variant of this part.
PIC18F2221-I/SS vs PIC18F2520-I/SS - which one should I choose?
The PIC18F2221-I/SS and PIC18F2520-I/SS share the same 28-pin SSOP footprint and identical pinout, but differ in Flash size: PIC18F2221 has 4KB Flash and 256 bytes EEPROM while PIC18F2520 has 32KB Flash and 1KB EEPROM, with the same 1.5KB SRAM. Both run at 40 MHz / 16 MIPS. Choose PIC18F2221 for cost-sensitive 4KB-or-less code; choose PIC18F2520 when firmware growth or bootloader is anticipated.
What is the best drop-in replacement for PIC18F2221-I/SS?
The closest drop-in replacements for the PIC18F2221-I/SS in the same 28-SSOP package are PIC18F2420-I/SS (16KB Flash upgrade, footprint-compatible), PIC18F2520-I/SS (32KB Flash upgrade, footprint-compatible) and PIC18F2221-E/SS (extended -40C to +125C temperature variant). All three share pinout, peripherals and electrical ratings within drop-in tolerance. PIC18F2221-I/SO is the SOIC-28 footprint variant (not drop-in for SSOP PCB).
Can PIC18F2321-I/SS replace PIC18F2221-I/SS on my PCB?
Yes, the PIC18F2321-I/SS is a drop-in upgrade for the PIC18F2221-I/SS on the same 28-SSOP footprint. The PIC18F2321 doubles program Flash to 8KB, retains 256 bytes EEPROM and 512 bytes SRAM, and adds two more 10-bit ADC channels and a second comparator. Pinout, VDD range and CPU clock are unchanged, so no PCB rework is required. Only firmware size and linker script must be updated.
Where can I download the PIC18F2221-I/SS datasheet PDF?
The official PIC18F2221-I/SS datasheet (document 39609F covering PIC18F2221/4221/2321/4321, 402 pages) can be downloaded from Microchip's product page at microchip.com/en-us/product/PIC18F2221 or directly from the Microchip document server at ww1.microchip.com/downloads/aes/DeviceDoc/39609F.pdf. Third-party mirrors also exist on alldatasheet.com and hotenda.com for reference.
Where do I find the PIC18F2221-I/SS pinout?
The PIC18F2221-I/SS pinout is published in the PIC18F2221 datasheet (document 39609F), Section 1.0 "Device Overview", table 1-3 for the 28-pin SPDIP/SOIC/SSOP package. Pin 1 is RA0/AN0 located at the top-left of the package as marked by the dot indicator; pin 28 is RB7/KBI3/PGD. The same pinout table applies to PIC18F2321-I/SS, PIC18F2420-I/SS and PIC18F2520-I/SS.
What microcontroller can I substitute for PIC18F2221-I/SS from another brand?
For cross-brand substitution the PIC18F2221-I/SS is uniquely characterized by its Microchip PIC18 core, so an architecturally identical competitor 28-pin SSOP drop-in does not exist; alternatives are ATmega88PA-AU (Atmel/Microchip) or STM8S003K3 (STMicroelectronics), but all require firmware porting because the instruction set, peripherals and toolchain are different. Engineers seeking a true drop-in should stay within the PIC18 family.
What are the key specifications of PIC18F2221-I/SS that engineers should know?
The PIC18F2221-I/SS is an 8-bit 40 MHz PIC18 Flash MCU with 4KB Flash, 256B EEPROM, 512B SRAM, 25 digital I/O, 13x 10-bit ADC, 2 comparators, 2x CCP, 1x MSSP (SPI/I2C) and an AUSART, running at 4.2-5.5V over -40C to +85C in a 28-SSOP package. It is the lowest-cost, lowest-memory entry point of the PIC18F2x21 family and is drop-in-compatible with PIC18F2321, PIC18F2420 and PIC18F2520 on the same footprint.

Engineering reference data for PIC18F2221-I/SS — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC18F2221-I/SS when you need an industrial-temperature, 5V-tolerant 8-bit MCU with 4KB or less of Flash in a 28-SSOP footprint at the lowest possible cost. It is the right answer for white-goods, HVAC and small-motor controllers where firmware fits in 4KB and code growth is unlikely. Choose PIC18F2321-I/SS if you anticipate needing up to 8KB of Flash without redesigning the PCB. Choose PIC18F2420-I/SS or PIC18F2520-I/SS when firmware growth or a bootloader is anticipated. Choose PIC18F2221-E/SS for outdoor or automotive under-hood applications above +85C. Choose PIC18LF2221-I/SS when the system runs from a 2.0-3.3V rail. All variants share the same 28-SSOP footprint, peripherals and toolchain, allowing a single PCB to support an entire product family.

Comparison with Alternatives

Parameter This Product PIC18F2321-I/SS PIC18F2420-I/SS PIC18F2520-I/SS PIC18F2221-E/SS PIC18LF2221-I/SS
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 28-SSOP (5.30 mm) 28-SSOP - same 28-SSOP - same 28-SSOP - same 28-SSOP - same 28-SSOP - same
Program Flash 4 KB 8 KB (+100%) 16 KB (+300%) 32 KB (+700%) 4 KB (identical) 4 KB (identical)
Data EEPROM 256 B 256 B 256 B 1 KB 256 B 256 B
Data SRAM 512 B 512 B 768 B 1.5 KB 512 B 512 B
Maximum Clock 40 MHz / 16 MIPS 40 MHz / 16 MIPS 40 MHz / 16 MIPS 40 MHz / 16 MIPS 40 MHz / 16 MIPS 40 MHz / 16 MIPS
ADC Channels 13x 10-bit 13x 10-bit (same) 10x 10-bit 10x 10-bit 13x 10-bit (same) 13x 10-bit (same)
VDD Range 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 2.0 V to 5.5 V
Operating Temperature -40C to +85C (Industrial) -40C to +85C -40C to +85C -40C to +85C -40C to +125C (Extended) -40C to +85C

Key Differentiators

  • Smallest-Flash, lowest-cost entry point of the PIC18F2x21 28-SSOP family (vs PIC18F2321-I/SS)
  • Same 28-SSOP footprint as PIC18F2420 and PIC18F2520 for free firmware upgrades (vs PIC18F2520-I/SS)
  • Industrial temperature range at standard cost; extended range available as -E variant (vs PIC18F2221-E/SS)
  • Higher VDD range vs LF variant supports 5V-only systems (vs PIC18LF2221-I/SS)

Design Notes

Place a 0.1 uF X7R ceramic decoupling capacitor within 5 mm of each VDD/VSS pair (pins 19/18 and 28/18). Add a bulk 10 uF tantalum or aluminum-polymer capacitor at the regulator output to suppress Icc transient dips during CCP/PWM switching. The PIC18F2221 will draw up to 35 mA at 40 MHz; ensure the regulator can deliver at least 2x peak current for cold-start Flash programming.

Keep the 28-SSOP PCB footprint to JEDEC standard land pattern with 0.65 mm pin pitch. Route the MCLR/VPP reset line with a 10 kohm pull-up to VDD and a 100 nF capacitor to ground to enable in-circuit serial programming (ICSP). Reserve 0.1 inch-pitch test points for PGD (pin 27) and PGC (pin 26) to allow debug ICD connection without removing the IC from the board.

Keep analog ADC inputs (RA0-RA5, RB0-RB2) away from high-current switching traces such as PWM outputs on RC1/RC2 and the DC bus. Use a single-point ground at the MCU's VSS pin and route noisy return currents (MOSFET gate drive, relay coils) through a separate ground plane region. If using the internal 4x PLL, place a 100 nF capacitor across the OSC1/OSC2 pins as datasheet section 3.0 indicates for crystal operation.

Do not confuse the -I/SS suffix (industrial temp / SSOP package) with -E/SS (extended temp / SSOP) or -I/SO (industrial temp / SOIC package). Verify ordering code with Microchip's part-number decoder before procuring - mismatches will result in non-pinout-compatible SSOP vs SOIC shipments. Also note that the LF (low-voltage) variants require different programming voltages than standard F parts.

For I2C bus operation via MSSP, place 4.7 kohm pull-ups on SCL (RC3) and SDA (RC4); for SPI master operation, ensure the SCK signal integrity by routing over a continuous ground plane. The AUSART TX/RX pins (RC6/RC7) are 5V TTL-level; for RS-485 add an external transceiver such as MCP2551. Always keep MCLR high during operation to avoid spurious resets.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS-compliant lead-free matte-tin finish per Microchip product declaration. Halogen-free per Microchip statement. AEC-Q100 qualification is not applicable to this general-purpose MCU; for automotive AEC-Q100 use the PIC18Fxxx-I/SS variant. REACH SVHC compliance is maintained per Microchip's chemical substance declarations.

Data verified on: 2026-09-26 — data verified and curated by XAIPART's component engineering team

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