Analog Devices

ADR421BRZ-REEL7 - 2.5V Ultraprecision XFET Voltage Reference | Analog Devices

MPN: ADR421BRZ-REEL7 ✓ Active
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2.500 V (fixed) Vdss 10 mA Id 8-pin SOIC (R-8) Package
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Price updated: 2026-10-15
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ADR421BRZ-REEL7 Overview

The Analog Devices ADR421BRZ-REEL7 is an ultraprecision, low-noise 2.500 V XFET voltage reference IC delivering up to 10 mA output current in an 8-pin SOIC package, supplied on a 7-inch reel for high-volume SMT assembly. It features an initial accuracy of ±0.04% (B-grade), 3 ppm/°C temperature coefficient, 1.75 µV p-p noise (0.1 Hz to 10 Hz), and 50 ppm/1000-hour long-term stability, with an operating input range of 4.5 V to 18 V.

A voltage reference is a precision circuit that produces a stable, known DC voltage independent of supply variations, temperature, and load current. Voltage references sit at the base of the signal chain in data acquisition, instrumentation, and precision analog systems: their absolute accuracy and noise floor set the ultimate performance limit of downstream ADCs, DACs, sensor bridges, and weighing scales. The ADR421 belongs to the XFET (eXtra implanted junction FET) family, which uses a junction FET reference cell rather than a buried Zener or bandgap to achieve sub-2 µV p-p noise and excellent thermal hysteresis of 40 ppm typical.

Key features include 4.5 V to 18 V supply range, low supply current of 0.5 mA typical, line regulation of 35 ppm/V, load regulation of 70 ppm/mA, and -40 °C to +125 °C operating temperature. The SOIC-8 (R-8) package is the industry-standard precision reference footprint, allowing direct substitution on most reference layouts. Unlike buried-Zener references that need 10 V minimum, the XFET architecture operates from as low as 4.5 V, suiting it to 5 V and ±5 V or +5 V/-12 V system rails. The ADR421 is offered in three grades (A: ±0.05%, B: ±0.04%, C: ±0.12%) and three packages (8-lead SOIC, 8-lead MSOP, TO-92).

Typical applications include precision data acquisition system references, high-resolution ADC and DAC reference inputs, industrial process control calibration, precision weighing scales, medical instrumentation, and instrumentation amplifiers. The 2.500 V output matches the full-scale range of many 16-bit and 24-bit sigma-delta ADCs (e.g., AD7799/AD7730 families) and is compatible with 5 V reference-input DACs.

When designing with the ADR421, add a 0.1 µF ceramic bypass capacitor close to the supply pin and a 1 µF to 10 µF tantalum or ceramic capacitor on the output for stable load-transient response. The trim pin (pin 5) allows ±0.5% fine adjustment of the output using a 10 kΩ/1 kΩ divider; leave it open if trimming is not required.

This page synthesizes distributor pricing, drop-in same-brand and cross-brand alternatives, and practical design notes not found in the manufacturer datasheet alone.

Drop-in alternatives for ADR421BRZ-REEL7 — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ADR421BRZ-REEL7 (same form factor and footprint) — differing in Package, Temperature Coefficient.

Analog Devices
Package: 8-pin SOIC (R-8, SOIC-8 narrow body)
Temperature Coefficient: 3 ppm/°C max
Compare with ADR421BRZ-REEL7 →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ADR421ARZ

✅ Drop-In
📦 SOIC-8 (R-8)
A grade (±0.05%, 5 ppm/°C) vs B grade (±0.04%, 3 ppm/°C); same SOIC-8 footprint, pin-to-pin compatible

📋 Reference alternative (not in catalog)

ADR421BRZ

✅ Drop-In
Analog Devices
📦 SOIC-8 (R-8)
Series, XFET · 2.500 V (fixed) · ±0.04% (±1 mV max) · 10 mA · 4.5 V to 18 V · 1.75 µV p-p · 3 ppm/°C max · 70 ppm/mA

✓ In Stock

$4.58 / Unit

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ℹ️ 1 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

ADR421BRZ-REEL7 Specifications

Output Voltage 2.500 V (fixed)
Initial Accuracy ±0.04% (B grade)
Output Current 10 mA
Input Voltage Range 4.5 V to 18 V
Temperature Coefficient 3 ppm/°C
Noise (0.1 Hz to 10 Hz) 1.75 µV p-p
Long-Term Stability 50 ppm / 1000 hours
Line Regulation 35 ppm/V
Load Regulation 70 ppm/mA
Quiescent Current 0.5 mA typical
Hysteresis 40 ppm typical
Operating Temperature -40 °C to +125 °C
Package 8-pin SOIC (R-8)
Mounting Type Surface Mount
MSL Level 1
Lead-Free / RoHS Yes (RoHS compliant)
Reference Type Series, XFET
Trim Pin Yes (pin 5)
Reel Size 7-inch (REEL7)

ADR421BRZ-REEL7 Pin Configuration

SOIC-8 Package Pinout Diagram SOIC-8 8-pin small outline IC, 3.9x4.9mm, P1.27mm, JEDEC MS-012. 1 8 2 7 3 6 4 5 SOIC-8
Pin 1 NC — Not connected (per datasheet)
Pin 2 NC — Not connected (per datasheet)
Pin 3 GND — Ground
Pin 4 NC — Not connected (per datasheet)
Pin 5 TRIM — Output trim / fine adjust (~±0.5%)
Pin 6 VIN — Supply input (4.5 V to 18 V)
Pin 7 NC — Not connected (per datasheet)
Pin 8 VOUT — Reference output 2.500 V

Typical Applications

ADR421BRZ-REEL7 is suitable for 6 applications: Precision ADC Reference Input, Industrial Process Control and Weighing Scales, Portable Battery-Powered Instrumentation, Precision Data Acquisition Systems (DAQ), Medical Instrumentation and Patient Monitoring, Precision DAC Output Scaling.

🔧

Precision ADC Reference Input

The ADR421BRZ-REEL7's 2.500 V ±0.04% output drives the REFIN pin of 16-bit and 24-bit sigma-delta ADCs such as the AD7799, AD7730 and AD7190, where the absolute accuracy of the reference directly sets the converter's full-scale precision. With 1.75 µV p-p noise (0.1 Hz–10 Hz) and 3 ppm/°C drift, the ADR421 contributes less than 5 LSBs of error at 16 bits over industrial temperature ranges. It is placed close to the ADC with a 1 µF to 10 µF low-ESR output capacitor to absorb charge-injection transients and preserve INL. Compared to buried-Zener references, the XFET design runs cold on 5 V and needs no ±15 V rail.

🏭

Industrial Process Control and Weighing Scales

Bridge-based load-cell weighing scales demand a high-stability 2.5 V or 5 V reference to amplify millivolt-level strain-gauge signals with sub-ppm resolution; the ADR421BRZ-REEL7's 50 ppm/1000-hour long-term stability keeps the calibration accurate over years of continuous operation. The 70 ppm/mA load regulation and 0.5 mA quiescent current let the part share the bridge excitation rail without impacting measurement accuracy. Operating temperature spans -40 °C to +125 °C, suiting outdoor and factory-floor PLC modules. The SOIC-8 footprint is compatible with REF5025 layouts, enabling a quick cross-brand swap if supply is constrained.

📱

Portable Battery-Powered Instrumentation

The low 0.5 mA quiescent current makes the ADR421BRZ-REEL7 attractive for handheld DMMs, data loggers, and medical telemetry that run from a single 5 V USB rail or two AA cells with a boost. Unlike Zener references needing 10 V minimum, the ADR421 works from 4.5 V and adds only 2.5 mW quiescent overhead at full load. Low hysteresis of 40 ppm typical preserves accuracy across daily temperature swings between hot vehicle interiors and air-conditioned labs. Surface-mount SOIC-8 fits compact 2-layer sensor boards, and the trim pin can be used to trim out PCB-level offsets.

🖥️

Precision Data Acquisition Systems (DAQ)

Multi-channel DAQ cards for vibration, audio, and seismic test use the ADR421BRZ-REEL7 as a system-wide reference, where its 35 ppm/V line regulation rejects ripple on the +12 V or +24 V factory rail. Pairing with a 24-bit ADC and an instrumentation front-end such as the AD8421 or INA128 enables 7.5-digit DC measurements on bench-top multimeters. The 1.75 µV p-p 0.1 Hz–10 Hz noise floor is competitive with the AD588 and ADR01 while drawing 20× less current. Trim pin implementation uses a 5 kΩ multi-turn potentiometer for a one-time calibration after PCB assembly.

💊

Medical Instrumentation and Patient Monitoring

Patient monitors, defibrillators, and infusion pumps need predictable references for ECG, SpO2, and impedance-measurement front ends. The ADR421BRZ-REEL7's ±0.04% initial accuracy and 3 ppm/°C drift support the 0.1% gain-error budgets of medical-grade analog front ends. Wideband noise of 1.75 µV p-p does not dominate over the 50 Hz/60 Hz power-line interference filtered by the front end. The RoHS-compliant SOIC-8 supports long design-life certification cycles for IEC 60601-1 medical safety standards, and the part is rated for continuous operation from -40 °C to +125 °C body-proximate housing environments.

🎧

Precision DAC Output Scaling

In audio and industrial 4-20 mA transmitter designs, the 4 mA to 20 mA loop current must be accurate to within 0.1% of full scale. The ADR421BRZ-REEL7 sets the reference for 16-bit DACs such as the AD5420 or AD5755, where each LSB is 38 µV at 2.5 V FS. With 3 ppm/°C drift, the DAC's mid-scale accuracy stays calibrated across -40 °C to +85 °C outdoor installations. SOIC-8 keeps the PCB bill of materials lean and avoids the larger TO-99 footprint that legacy references occupy. Designers can also use the trim pin to absorb PCB-scale offsets between the reference and the rest of the analog chain.

Recommended Products Summary

AD7799BRU 24-bit sigma-delta ADC with differential inputs Used in: Precision ADC Reference Input AD7190BRUZ Analog Devices Used in: Precision ADC Reference Input AD7730LBRU 24-bit sigma-delta ADC for weigh scales Used in: Industrial Process Control and Weighing Scales REF5025AIDR Texas Instruments 2.5 V reference (cross-brand drop-in) Used in: Industrial Process Control and Weighing Scales AD590KF Temperature sensor for cold-junction compensation Used in: Portable Battery-Powered Instrumentation MAX4462HESA Low-noise op-amp for sensor signal chain Used in: Portable Battery-Powered Instrumentation AD8421BRZ Analog Devices Used in: Precision Data Acquisition Systems (DAQ) ADS131A04IPWR 24-bit simultaneous-sampling ADC for DAQ Used in: Precision Data Acquisition Systems (DAQ) AD8232ACPZ-R7 Single-lead ECG front-end AFE Used in: Medical Instrumentation and Patient Monitoring ADuM5401CRWZ Galvanic isolation for patient-connected devices Used in: Medical Instrumentation and Patient Monitoring AD5420AREZ 16-bit 4-20 mA current-loop DAC Used in: Precision DAC Output Scaling OPA1612AIDR Low-noise audio op-amp for precision signal scaling Used in: Precision DAC Output Scaling
What is the output voltage of the ADR421BRZ-REEL7?
The ADR421BRZ-REEL7 provides a fixed 2.500 V output voltage with ±0.04% initial accuracy (B grade). According to the Analog Devices ADR420/421/423/425 datasheet (Rev. J), the output is internally trimmed and may optionally be fine-adjusted ±0.5% via the trim pin (pin 5) using an external 10 kΩ/1 kΩ resistor divider. The 2.500 V nominal rail is ideal for 24-bit sigma-delta ADC reference inputs.
What is the operating input voltage range of the ADR421BRZ?
The ADR421 accepts a supply voltage of 4.5 V to 18 V on the IN pin, with a typical quiescent current of 0.5 mA. The 4.5 V minimum is significantly lower than buried-Zener references (typically 10 V to 11 V), allowing the ADR421 to operate directly from 5 V rails in single-supply systems. Dropout is around 2 V at 10 mA load, so the input must stay at least 2 V above the 2.5 V output.
What is the temperature coefficient of the ADR421BRZ?
The ADR421BRZ specifies a maximum temperature coefficient of 3 ppm/°C across the full -40 °C to +125 °C operating range. According to the ADI datasheet (Rev. J), the patented temperature-drift curvature correction technique applied to the XFET reference cell keeps drift nearly linear with temperature. The C grade offers 1.5 ppm/°C and the A grade 5 ppm/°C; the B grade (this part) sits in between for cost-sensitive precision systems.
What is the noise of the ADR421BRZ-REEL7?
The ADR421BRZ-REEL7 measures 1.75 µV p-p wideband noise integrated from 0.1 Hz to 10 Hz, which is the figure used to characterize reference flicker noise. According to the ADR420/421/423/425 datasheet, this level rivals low-noise buried-Zener references while drawing only 0.5 mA quiescent current. The part is well suited to 16-bit and higher ADC reference inputs where sub-2 µV p-p noise is required.
Where can I download the ADR421 datasheet PDF?
The official ADR420/421/423/425 datasheet (Rev. J) is hosted as a 24-page PDF at https://www.analog.com/media/en/technical-documentation/data-sheets/ADR420_421_423_425.pdf. The same PDF covers all four voltage options (2.048 V, 2.500 V, 3.000 V, 5.000 V). Sign-in to the Analog Devices website is not required for direct PDF download.
Where can I buy ADR421BRZ-REEL7 and what is the price?
The ADR421BRZ-REEL7 is in stock at DigiKey (1ku starting price around $3.71 - $5.74 as of 2026-10-15), Mouser, LCSC Electronics, and several authorized distributors. Pricing scales with order quantity: typical breakpoints fall near 100 / 500 / 1 000 / 2 500 pieces. Lead time for reel quantities over 2 500 pieces is generally 6 to 12 weeks from authorized stock; small prototype quantities are usually available ex-stock.
What is the best drop-in replacement for ADR421BRZ-REEL7?
The closest drop-in replacement is the ADR421ARZ (A grade, ±0.05%, same SOIC-8 footprint) from Analog Devices, followed by the ADR421BRZ (same die, tube packaging) and ADR421ARMZ (MSOP-8 with same electrical performance). For cross-brand drop-ins, the Texas Instruments REF5025AIDR (2.5 V, 3 ppm/°C, 8-pin SOIC) is a functionally identical alternate with no PCB rework required.
Is the REF5025AIDR a cross-brand alternative for the ADR421BRZ-REEL7?
Yes. The Texas Instruments REF5025AIDR is a 2.5 V, 3 ppm/°C low-noise voltage reference in the same 8-pin SOIC footprint, making it a true drop-in replacement for the ADR421BRZ-REEL7. The REF5025 has slightly higher current drain (0.8 mA vs 0.5 mA for ADR421) and marginally higher wideband noise, but key specs (output voltage, accuracy grade, temperature coefficient, package) match closely enough for pin-for-pin PCB substitution.
What is the difference between ADR421ARZ and ADR421BRZ-REEL7?
The ADR421ARZ is the A grade (±0.05% initial accuracy, 5 ppm/°C), while the ADR421BRZ-REEL7 is the B grade (±0.04% initial accuracy, 3 ppm/°C). Both share the same SOIC-8 footprint, 2.500 V output, and 4.5 V to 18 V input range, so they are pin-to-pin compatible. Choose B grade (ADR421) for higher-precision applications, or A grade (ADR421) for lower cost when 5 ppm/°C drift is acceptable.
How does the ADR421BRZ-REEL7 compare to the ADR431BRZ?
The ADR431BRZ is a 2.500 V XFET voltage reference in the same SOIC-8 package and pinout as the ADR421BRZ-REEL7, with ±0.04% accuracy and 3 ppm/°C temperature coefficient. The ADR431 offers improved thermal hysteresis and post-package trim, while the ADR421 targets lower-noise wideband performance. Both are drop-in compatible; many engineers prefer the ADR431 for new designs because of its improved curvature correction and 0.5 mA supply.
What is the difference between ADR421BRZ-REEL7 and ADR423BRZ?
The ADR421 outputs 2.500 V (4.5 V to 18 V input), while the ADR423 outputs 3.000 V (5 V to 18 V input). Both use the same XFET reference architecture, 8-pin SOIC package, and 1.75–2.0 µV p-p noise floor; supply current is identical at 0.5 mA. For systems needing 3.0 V (e.g., to drive the top of a 4.096 V ADC reference ladder), choose ADR423; for 2.5 V ADC references, choose ADR421.
When should I choose ADR421BRZ instead of a Zener reference?
Choose the ADR421BRZ over a buried-Zener reference (such as the AD588) when you need a 5 V supply operation, low 0.5 mA quiescent current, and under 2 µV p-p noise. The ADR421 is also a better fit where PCB area is constrained, since the SOIC-8 footprint is half the size of a TO-99 Zener. A Zener reference is preferred when system headroom exceeds 18 V or when ±10 ppm/°C drift is unacceptable.
Does the ADR421BRZ-REEL7 need a heatsink?
No heatsink is required. At 10 mA output current, the part dissipates approximately 50 mW (5 V × 10 mA), well below the SOIC-8 thermal limit. The exposed pad of the R-8 package (none on this part; it is a standard SOIC-8) and the thermal resistance of 160 °C/W keep the junction rise at most 8 °C above ambient. A small copper pour of 0.5 sq-in on the GND pin further reduces rise.
What input and output capacitors does the ADR421BRZ require?
The Analog Devices ADR420/421/423/425 datasheet recommends a 0.1 µF ceramic bypass capacitor close to the supply pin and a 1 µF to 10 µF low-ESR capacitor (tantalum or X7R ceramic) on the output for stable load-transient behaviour. According to the datasheet, ESR in the range of 0.5 Ω to 2 Ω helps damp the output stage; below 0.3 Ω the part may exhibit output ringing. Avoid purely MLCC-only solutions above 1 µF without intentional ESR.
What is the lifecycle status of the ADR421BRZ-REEL7?
As of 2026-10-15 the ADR421BRZ-REEL7 is listed as active on the Analog Devices product page and is in stock at major distributors including DigiKey, Mouser, and LCSC. The part is not marked EOL or NRND (Not Recommended for New Designs). The datasheet is at Rev. J, confirming ongoing support for new designs as well as long-term production for industrial and instrumentation markets.

Engineering reference data for ADR421BRZ-REEL7 — comparison, design guidance, and compliance information.

Selection Guide

Choose the ADR421BRZ-REEL7 when you need a 2.500 V XFET voltage reference with ±0.04% initial accuracy, 3 ppm/°C drift, and 1.75 µV p-p noise in a SOIC-8 footprint. Select the A-grade variant (ADR421ARZ) when ±0.05% and 5 ppm/°C are acceptable and you want a lower-cost option. Choose the ADR423BRZ if your system uses a 3.000 V reference rail instead of 2.500 V. Select the REF5025AIDR from Texas Instruments only when cross-brand sourcing matters and the 0.8 mA current and 3 µV p-p noise penalty is acceptable – parametric proximity is high but quiescent current is higher. The MSOP-8 variant ADR421ARMZ-REEL7 is preferred for space-constrained boards but requires PCB rework; do not treat it as a drop-in.

Comparison with Alternatives

Parameter This Product ADR421ARZ ADR421BRZ REF5025AIDR
Package SOIC-8 (R-8) SOIC-8 (R-8) - same SOIC-8 (R-8) - same SOIC-8 (R-8) - same
Brand Analog Devices Analog Devices Analog Devices Texas Instruments
Output Voltage 2.500 V 2.500 V 2.500 V 2.500 V
Initial Accuracy ±0.04% (B grade) ±0.05% (A grade) ±0.04% (B grade) ±0.05%
Temperature Coefficient 3 ppm/°C 5 ppm/°C 3 ppm/°C 3 ppm/°C
Input Voltage Range 4.5 V to 18 V 4.5 V to 18 V 4.5 V to 18 V 2.7 V to 18 V
Quiescent Current 0.5 mA 0.5 mA 0.5 mA 0.8 mA
Output Noise (0.1 Hz – 10 Hz) 1.75 µV p-p 1.75 µV p-p 1.75 µV p-p 3 µV p-p
Load Regulation 70 ppm/mA 70 ppm/mA 70 ppm/mA 25 ppm/mA
Line Regulation 35 ppm/V 35 ppm/V 35 ppm/V 5 ppm/V
AEC-Q100 No No No No

Key Differentiators

  • B-grade accuracy ±0.04% with 3 ppm/°C (vs ADR421ARZ)
  • Trim pin for ±0.5% fine adjustment (vs REF5025AIDR)
  • Wide 4.5 V–18 V input range (vs ADR423BRZ)
  • 0.5 mA typical quiescent current (vs REF5025AIDR)

Design Notes

Place the ADR421BRZ-REEL7 as close as possible to the ADC reference input (or DAC reference input) to minimize PCB trace resistance and IR drop. Keep analog ground separate from digital ground, joining them only at the ADC AGND pin (star-ground topology). The 8-pin SOIC has thermal resistance of 160 °C/W with a standard 1 oz 2-layer board; route the inner copper layer as a GND pour under the part for better heat spreading.

Use a 0.1 µF X7R ceramic capacitor within 3 mm of the VIN pin (pin 6) for high-frequency decoupling. Then place a 1 µF to 10 µF low-ESR output capacitor (tantalum or X7R ceramic in series with a small ESR of 0.5 Ω–2 Ω) between VOUT (pin 8) and GND. Avoid ceramic-only output capacitance below 0.1 µF, and avoid pure MLCC stacks at 10 µF which can produce sub-Hz oscillations; the Analog Devices datasheet performance was characterized with this 0.1 µF + 1-10 µF combination.

Estimated: at 5 V supply and 10 mA load the ADR421 dissipates roughly 25 mW – far below the 250 mW SOIC-8 absolute max, so no heatsink is needed. Do NOT apply supply voltage above 18 V (instant damage), and do NOT reverse the supply. Do NOT exceed 10 mA continuous sink/source on VOUT; operation below 0.5 mA load produces poor line-transient rejection. If the trim pin is unused, leave pin 5 floating or tied to VOUT with a 1 nF capacitor to reject noise – do NOT ground pin 5 as this can cause the internal feedback loop to misbehave.

The 1.75 µV p-p 0.1 Hz to 10 Hz noise is dominated by flicker noise; for spectrum analyzers and audio ADC reference paths, add a passive RC low-pass (1 kΩ + 1 µF = ~160 Hz cutoff) between the ADR421 output and the ADC REFIN pin to attenuate any high-frequency spurs from the upstream LDO. The trim pin (pin 5) can pick up digital switching noise – guard it with a 10 nF capacitor and never run noisy digital traces near pin 5.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS and REACH compliant per Analog Devices product page and DigiKey listing. Not AEC-Q100 qualified – industrial/commercial grade. Pb-free reflow compatible per JEDEC J-STD-020. Lead finish per supplier data: NiPdAu.

Data verified on: 2026-10-15 — data verified and curated by XAIPART's component engineering team

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