Microchip Technology

ATSAM4LS2AA-MU - 48MHz Cortex-M4 MCU 128KB Flash QFN-48 | Microchip

MPN: ATSAM4LS2AA-MU ✓ Active
In Stock Ships in 1-3 business days
3.3 V nominal Vdss 90 uA/MHz Id 48-QFN (7x7 mm) with exposed pad Package 48 MHz Speed 128 KB (128K x 8) Memory
From $3.55 USD / Unit
MOQ: 1 |
Price updated: 2026-09-19
Volume Pricing
Qty Unit Price Extended
1 $5.5 $5.50
10 $4.95 $49.50
100 $4.4 $440.00
500 $3.95 $1,975.00
1,000 $3.55 $3,550.00
ℹ️ All prices are in USD

ATSAM4LS2AA-MU Overview

The Microchip Technology ATSAM4LS2AA-MU is a 32-bit ARM Cortex-M4 flash microcontroller running at 48 MHz with 128 KB of embedded Flash, 32 KB of SRAM, and an integrated USB device controller, housed in a 48-pin QFN (7x7 mm) package with exposed pad.

A microcontroller unit (MCU) is a single-chip embedded processor that integrates a CPU core, program memory, data memory, and peripheral functions such as timers, communication interfaces, and analog blocks. The SAM4L family sits within Microchip's (formerly Atmel) 32-bit ARM-based MCU portfolio, which spans from the low-power SAM L and SAM D families up to high-performance SAM E parts with floating-point units. MCUs are the top-level building block of embedded systems, powering industrial control, consumer devices, and IoT nodes.

The defining feature of the ATSAM4LS2AA-MU is class-leading power efficiency: 90 uA/MHz in active mode, 1.5 uA in sleep mode, and wake-up times down to 1.5 us, which Microchip identifies as the lowest power and fastest wake-up among Cortex-M4 devices. The SAM4L architecture adds a Peripheral Event System and SleepWalking, allowing peripherals to operate and respond autonomously while the CPU core remains in low-power sleep.

Peripherals include USB device, USART, TWI (I2C), SPI, 12-bit ADC, DAC, capacitive touch support (Peripheral Touch Controller), and an AES/DES cryptographic engine on some family members. The Cortex-M4 core delivers DSP-oriented instructions for efficient digital filtering and control-loop mathematics at 48 MHz.

Typical applications include battery-powered sensor nodes, portable medical instruments, low-power IoT endpoints, and touch-sensing human interface devices where sleep current and wake-up latency dominate battery life.

Design consideration: the 48-QFN exposed-pad package requires a solid ground connection through the PCB thermal pad; use via stitching to the ground plane for both thermal dissipation and signal-integrity during EMI testing.

This page synthesizes distributor pricing, drop-in alternatives within the SAM4L family, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for ATSAM4LS2AA-MU — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAM4LS2AA-MU (same form factor and footprint) — differing in Package, RoHS Status, Supply Voltage, Flash Memory, SRAM.

Microchip Technology
Package: 64-QFN (9x9 mm) with exposed pad
SRAM: 32 KB (32K x 8)
Compare with ATSAM4LS2AA-MU →
Microchip Technology
Package: 64-VQFN (9x9 mm) Exposed Pad
RoHS Status: Green / RoHS compliant per Mouser listing
Supply Voltage: 1.8V / 3.3V
Compare with ATSAM4LS2AA-MU →
Microchip Technology
RoHS Status: Compliant (GREEN package)
Supply Voltage: 1.8V / 2.5V / 3.3V
Compare with ATSAM4LS2AA-MU →
Microchip Technology
Package: 48-QFN (7x7 mm)
Flash Memory: 256 KB (256K x 8)
Compare with ATSAM4LS2AA-MU →
Microchip Technology
Package: 64-QFN (9x9 mm)
RoHS Status: Compliant (GREEN per Mouser listing)
Supply Voltage: 3.3 V
Compare with ATSAM4LS2AA-MU →
Microchip Technology
Package: 48-QFN (7x7 mm)
Compare with ATSAM4LS2AA-MU →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAM4LS4AA-MU

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-Bit · 48 MHz · 256 KB (256K x 8) · 90 uA/MHz · 1.5 uA · down to 1.5 us

✓ In Stock

$3.95 / Unit

View Datasheet →

ATSAM4LC2AA-MU

✅ Drop-In ⚠️ 参数待验证
📦 48-QFN (7x7 mm)
LC ultra-low-power variant, same 128 KB Flash and package, slightly lower max performance focus

📋 Reference alternative (not in catalog)

ATSAM4LS2BA-MU

✅ Drop-In ⚠️ 参数待验证
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-bit · 48 MHz · 128KB (128K x 8) · 32KB · 1.8V / 3.3V · SAM4L · 64

✓ In Stock

$3.79 / Unit

View Datasheet →

ATSAM4LS4BA-MU

✅ Drop-In ⚠️ 参数待验证
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-Bit · 48 MHz · 256 KB (256K x 8) · 32 KB · 3.3 V · 64-QFN (9x9 mm) · Surface Mount

✓ In Stock

$1.85 / Unit

View Datasheet →

ATSAM3N4AA-MU

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M3 revision 2.0 · 32-bit · 48 MHz · 256 KB (256K x 8) · FLASH · 24 KB (24K x 8) · 34 · 1.62 V to 3.6 V

✓ In Stock

$4.1 / Unit

View Datasheet →

ATSAM4LS2AA-MU Maximum Ratings & Electrical Characteristics

Core Processor ARM Cortex-M4
Core Size 32-bit
Maximum Clock Frequency 48 MHz
Flash Memory 128 KB (128K x 8)
SRAM 32 KB
Supply Voltage 3.3 V nominal
Active Mode Current 90 uA/MHz
Sleep Mode Current 1.5 uA
Wake-up Time down to 1.5 us
Package 48-QFN (7x7 mm) with exposed pad
Mounting Type Surface Mount
Operating Temperature Industrial temperature range
USB USB device controller
Peripherals Peripheral Event System, SleepWalking, capacitive touch support
Series SAM4L
RoHS Status Compliant (GREEN package per Mouser listing)
Packaging Tray (MRL A per Mouser)

ATSAM4LS2AA-MU 48-qfn (7x7 mm) with exposed pad Pin Configuration Guide

Pin configuration for ATSAM4LS2AA-MU (48-qfn (7x7 mm) with exposed pad package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

48-qfn (7x7 mm) with exposed pad package pinout diagram for ATSAM4LS2AA-MU

No detailed pinout data available for ATSAM4LS2AA-MU.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4LS2AA-MU is suitable for 6 applications: Battery-Powered IoT Sensor Nodes, Capacitive Touch User Interfaces, Portable Medical and Health Instruments, USB-Connected Industrial Sensors, Energy-Harvesting and Wearable Devices, Smart Metering and Building Automation.

🧩

Battery-Powered IoT Sensor Nodes

The ATSAM4LS2AA-MU is a strong fit for battery-powered IoT endpoints because its 1.5 uA sleep current and 90 uA/MHz active efficiency directly translate into years of coin-cell life. A typical node sleeps in Wait mode at 1.5 uA while the SleepWalking peripheral event system monitors sensors via TWI or SPI; when a threshold is crossed, the Cortex-M4 core wakes in about 1.5 us to process data and transmit over an RF link. Unlike always-on solutions, the MCU spends over 99% of its lifetime in sleep, so average system current can stay in the low microamp range. Designers should budget for RF module sleep current too, since it often dominates the total budget.

🔧

Capacitive Touch User Interfaces

The SAM4L family integrates a Peripheral Touch Controller (PTC) that automates capacitive touch acquisition for buttons, sliders, and wheels without CPU intervention, making the ATSAM4LS2AA-MU ideal for touch-sensing HMI products. The PTC works with the SleepWalking architecture so the MCU can detect a touch while drawing minimal current, then wake the 48 MHz Cortex-M4 to run UI logic and respond over USB device or UART to a host. Microchip provides touch tuning libraries and reference designs for the SAM4L PTC. Because wake-up is only 1.5 us, perceived latency is imperceptible, and the 128 KB Flash comfortably holds touch tuning data plus application code.

💊

Portable Medical and Health Instruments

Portable medical instruments such as glucose meters, pulse oximeters, and patient-worn monitors benefit from the ATSAM4LS2AA-MU's combination of a DSP-capable Cortex-M4 core and microamp-level sleep. Signal-conditioning loops can use Cortex-M4 multiply-accumulate instructions to run digital filters at 48 MHz, then the device returns to 1.5 uA sleep between measurements, extending battery replacement intervals. The 12-bit ADC provides sufficient resolution for many physiological front-ends, and the Peripheral Event System can chain ADC samples to timers without CPU involvement, reducing jitter. Long product lifecycles and industrial temperature grade support the qualification demands of medical device platforms.

🏭

USB-Connected Industrial Sensors

The integrated USB device controller makes the ATSAM4LS2AA-MU a natural choice for industrial sensors and dongles that report to PCs or PLC configuration tools over USB. Combined with the industrial temperature grade noted in the Mouser listing, the device tolerates cabinet and factory-floor environments. A typical design samples a sensor through the ADC or a SPI/TWI front-end, applies filtering with Cortex-M4 DSP instructions, and streams results over USB while the USB peripheral SleepWalks during idle intervals to hold current near 1.5 uA. The 48-QFN exposed-pad package must be well grounded to pass EMC testing on industrial machinery.

Energy-Harvesting and Wearable Devices

Energy-harvesting systems, where available power is measured in microwatts, demand exactly the profile the ATSAM4LS2AA-MU delivers: 90 uA/MHz active operation to maximize work per harvested joule and 1.5 uA sleep to preserve stored charge. The 1.5 us wake-up allows the firmware to exploit short energy bursts opportunistically, executing measurement and processing tasks before the supply droops. Wearable devices gain the same benefit plus fast touch response via the PTC. Designers should size the storage capacitor so the 48 MHz active phase completes within the harvested energy envelope, and use the event system to minimize active time per duty cycle.

🌐

Smart Metering and Building Automation

Smart meters and building automation nodes run for a decade or more on mains or battery backup, so the ATSAM4LS2AA-MU's 1.5 uA sleep and SleepWalking communication peripherals are decisive advantages. A metering node can keep the TWI or USART monitoring a measurement IC while the CPU sleeps, accumulating pulses or reading registers autonomously, then wake the Cortex-M4 to compute consumption, update the display, and publish over wired or RF links. The 128 KB Flash holds metrology firmware plus communication stacks, and the industrial temperature rating covers outdoor enclosures. Cryptographic capability in the SAM4L family supports authentication of metering data.

What is the ATSAM4LS2AA-MU microcontroller?
The ATSAM4LS2AA-MU is a 32-bit ARM Cortex-M4 flash microcontroller from Microchip Technology (Atmel SAM4L series) running at 48 MHz with 128 KB Flash and 32 KB SRAM in a 48-pin QFN (7x7 mm) package. According to Microchip product data, it achieves 90 uA/MHz active current, 1.5 uA sleep current, and wake-up times down to 1.5 us, the lowest power figures in Microchip's Cortex-M4 portfolio.
How much Flash and SRAM does the ATSAM4LS2AA-MU have?
The ATSAM4LS2AA-MU contains 128 KB (128K x 8) of embedded Flash memory and 32 KB of SRAM. According to the DigiKey product listing and the FindIC datasheet summary, the device is a member of the SAM4L series with these memory sizes, plus a USB device controller and a Peripheral Event System for autonomous peripheral operation while the CPU sleeps.
What is the power consumption of the ATSAM4LS2AA-MU in sleep mode?
The ATSAM4LS2AA-MU draws approximately 1.5 uA in sleep mode and 90 uA/MHz in active mode, with wake-up times down to 1.5 us. According to Microchip's SAM4L product overview, these figures are the lowest power and fastest wake-up combination available in a Cortex-M4 device, making the part well suited to coin-cell or energy-harvesting battery applications.
What is the difference between ATSAM4LS2AA-MU and ATSAM4LS4AA-MU?
The primary difference is Flash capacity: the ATSAM4LS4AA-MU provides 256 KB of Flash versus 128 KB on the ATSAM4LS2AA-MU. Both are SAM4L series Cortex-M4 parts at 48 MHz in the same 48-QFN (7x7) footprint, so the LS4 variant can be used where more code space is needed, while the LS2 suits cost- and power-optimized designs. Peripherals and pinout are largely shared across the family.
Can the ATSAM4LS2AA-MU be used for battery-powered IoT applications?
Yes, the ATSAM4LS2AA-MU is specifically designed for battery-powered applications. With 1.5 uA sleep current, 90 uA/MHz active efficiency, and 1.5 us wake-up, plus the SleepWalking feature that lets peripherals like the TWI, SPI, or ADC wake the system autonomously, a sensor node can spend most of its life in sleep and still meet demanding latency requirements on a small battery.
Does the ATSAM4LS2AA-MU support USB?
Yes, the ATSAM4LS2AA-MU integrates a USB device controller, as stated in the Microchip SAM4L product description: the device features a USB device, a peripheral event system, and SleepWalking. The USB peripheral can remain functional under CPU sleep in supported low-power modes, enabling USB-connected battery devices with long standby times.
What package does the ATSAM4LS2AA-MU come in?
The ATSAM4LS2AA-MU is supplied in a 48-pin QFN (7x7 mm) package with an exposed pad, coded HVQCCN per the Partstack package data. The exposed pad must be soldered to the PCB ground plane for reliable grounding and thermal performance. The MU suffix on Microchip/Atmel parts denotes the QFN package in tray packaging (MRL A per the Mouser listing).
Where can I download the ATSAM4LS2AA-MU datasheet PDF?
The ATSAM4LS2AA-MU datasheet is available from Microchip's official product page at microchip.com/en-us/product/ATSAM4LS2A, and datasheet aggregators such as Octopart and Datasheets.com also host the PDF (a 2014-published revision of roughly 2.4 MB is listed by FindIC). Always prefer the manufacturer page for the latest revision of the SAM4L datasheet and electrical characteristics.
What is the best drop-in replacement for ATSAM4LS2AA-MU?
The best drop-in replacement within the same family is the ATSAM4LC2AA-MU, which shares the SAM4L architecture and 48-QFN footprint with 128 KB Flash but trades some top-speed operation for even lower power. Within the LS sub-family, the ATSAM4LS2BA-MU is the same 128 KB device in an updated part revision with identical footprint. Verify pinout and peripheral mapping against the SAM4L datasheet before substituting.
Is ATSAM4LS2AA-MU the same as ATSAM4LS2AA-MUR?
Functionally they are the same silicon: the ATSAM4LS2AA-MU is supplied in trays while the -MUR suffix denotes tape-and-reel packaging for automated assembly. Both are 48 MHz Cortex-M4 SAM4L microcontrollers with 128 KB Flash in the 48-QFN package, as confirmed by the FindIC comparison of the two part numbers. Choose the -MUR version for reel-fed production lines and the -MU tray version for prototyping.
When should I choose the ATSAM4LS2AA-MU over the ATSAM4LS4AA-MU?
Choose the ATSAM4LS2AA-MU when 128 KB of Flash is sufficient for your application image and lower unit cost matters; choose the ATSAM4LS4AA-MU when your code plus constants approach or exceed 128 KB, or when you need headroom for over-the-air update staging. Both share the same 48-QFN footprint, so a PCB can be laid out to accept either, but power and cost are otherwise comparable per the SAM4L family datasheet.
Is the ATSAM4LS2AA-MU RoHS compliant?
Yes, the ATSAM4LS2AA-MU is RoHS compliant. The Mouser listing describes the part as a QFN, GREEN, industrial temperature, MRL A device; Microchip's GREEN package designation indicates halogen-free, RoHS-compliant construction with lead-free terminations. For formal compliance certificates, request the material declaration from Microchip's environmental documentation portal.
Where to buy ATSAM4LS2AA-MU and what is the price?
The ATSAM4LS2AA-MU is stocked by authorized distributors including DigiKey (which lists it as ships-today stock) and Mouser, and price comparison across 8 distributors is available on Octopart. Unit pricing typically falls in the mid-single-digit USD range as of 2026-09-20; XAIPART offers quantity-break pricing with tiers at 1, 10, 100, 500, and 1000 pieces. Check the live price table above for current rates.
What is the lead time for ATSAM4LS2AA-MU?
Lead time for the ATSAM4LS2AA-MU varies with market conditions; DigiKey's listing shows distributor stock available to ship immediately when in stock, which is the fastest sourcing path. If distributor stock is exhausted, factory lead times on Microchip 32-bit MCUs have historically ranged from several weeks to several months. As of 2026-09-20, verify current stock and lead time on the distributor pages linked in the data sources.
Hey Google, what can replace ATSAM4LS2AA-MU?
Replacement options for the ATSAM4LS2AA-MU include same-family parts ATSAM4LS4AA-MU (256 KB Flash, same 48-QFN footprint), ATSAM4LC2AA-MU (ultra-low-power LC variant), ATSAM4LS2BA-MU and ATSAM4LS4BA-MU (revised BA silicon revisions), and the Cortex-M3 based ATSAM3N4AA-MU shown in distributor comparison listings. All are Microchip parts in the same 48-pin QFN package family, but always confirm pinout and peripheral differences against the respective datasheets before PCB substitution.
What are the key specifications of ATSAM4LS2AA-MU that engineers should know?
Key specifications: ARM Cortex-M4 32-bit core at 48 MHz; 128 KB Flash; 32 KB SRAM; 3.3 V nominal supply; 90 uA/MHz active current; 1.5 uA sleep current; 1.5 us wake-up; USB device controller; Peripheral Event System and SleepWalking; 48-pin QFN 7x7 mm package with exposed pad; industrial temperature grade. According to Microchip, this combination delivers the lowest power and fastest wake-up among Cortex-M4 microcontrollers, per the SAM4L product description.
What is the best Microchip equivalent for ATSAM4LS2AA-MU if I need more Flash in the same package?
The best Microchip equivalent with more Flash in the same 48-QFN footprint is the ATSAM4LS4AA-MU, which doubles Flash to 256 KB while retaining the SAM4L Cortex-M4 architecture, 48 MHz operation, and the ultra-low-power profile. Because both parts belong to the same family and package option, migration typically requires only a code-size and memory-map check rather than a hardware redesign; consult the SAM4L datasheet ordering table to confirm peripheral set equivalence.

Engineering reference data for ATSAM4LS2AA-MU — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4LS2AA-MU when your application needs a Cortex-M4 with DSP capability, USB device connectivity, and 128 KB Flash in a compact 48-QFN footprint, with battery life governed by 1.5 uA sleep and 90 uA/MHz active current. Choose the ATSAM4LS4AA-MU when code size approaches the 128 KB limit, since it doubles Flash in the identical footprint with no redesign. Choose the ATSAM4LC2AA-MU when ultra-low active power outweighs top-speed operation, such as in energy-harvesting designs. Choose the ATSAM3N4AA-MU only when cost matters more than DSP performance, accepting the Cortex-M3 core's lack of single-cycle MAC instructions. All five options share the 48-QFN package, so a single PCB layout can cover the range; validate peripheral mapping per the SAM4L datasheet ordering table before committing to a substitution.

Comparison with Alternatives

Parameter This Product ATSAM4LS4AA-MU ATSAM4LC2AA-MU ATSAM3N4AA-MU
Package 48-QFN (7x7 mm) 48-QFN (7x7 mm) - same 48-QFN (7x7 mm) - same 48-QFN (7x7 mm) - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core ARM Cortex-M4 ARM Cortex-M4 ARM Cortex-M4 ARM Cortex-M3
Max Frequency 48 MHz 48 MHz 48 MHz 48 MHz
Flash Memory 128 KB 256 KB 128 KB 256 KB

Key Differentiators

  • Cortex-M4 DSP instructions at ultra-low power (vs ATSAM3N4AA-MU)
  • Best power figure in its Flash class (vs ATSAM4LS4AA-MU)
  • Balanced power/performance vs LC ultra-low-power line (vs ATSAM4LC2AA-MU)

Design Notes

The 48-QFN (7x7 mm) exposed-pad package requires the center thermal pad to be soldered to a well-designed ground island on the PCB. Use a 3x3 or 4x4 via array under the pad stitched to the internal ground plane to guarantee low-impedance ground return and acceptable thermal dissipation. Undersoldering the exposed pad is a common cause of intermittent USB communication and analog noise on SAM4L designs, because the pad is the primary ground connection for the die.

To actually realize the datasheet 1.5 uA sleep current, firmware must gate or disable unused peripherals and clocks before entering Wait mode; any remaining active clock (including USB or an oscillator left running) can raise sleep current by orders of magnitude. Follow the Microchip SAM4L low-power design application notes: configure the SleepWalking clock sources (OSC32K or RC32K) for the peripherals that must keep running, and verify measured sleep current on the bench with a precision ammeter, not just in simulation.

Flash programming and debug use the Cortex-M4 SWD interface; reserve the SWDIO/SWCLK pins and include a standard 2x5 Cortex debug connector even in production boards, since field firmware updates and fault diagnostics depend on it. Additionally, when migrating between SAM4L LS and LC variants, confirm the part-specific peripheral instance map in the device datasheet, as DMA channel assignment and USB clock source options differ slightly across family members.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Unknown

Mouser lists the part as QFN, GREEN, IND TEMP, MRL A; Microchip GREEN package designation indicates RoHS/halogen-free lead-free construction. Formal REACH and conflict-minerals declarations should be requested from Microchip environmental documentation.

Data verified on: 2026-09-20 — data verified and curated by XAIPART's component engineering team

Related Searches

ATSAM4LS2AA-MU ATSAM4LS2AA-MU datasheet Microchip ATSAM4LS2AA-MU ATSAM4LS2AA-MU 128KB Flash Cortex-M4 microcontroller 48-QFN 7x7 ARM Cortex-M4 MCU low power ATSAM4LS2AA-MU battery powered IoT sensor ATSAM4LS2AA-MU vs ATSAM4LS4AA-MU ATSAM4LS2AA-MU drop-in replacement ATSAM4LS2AA-MU price buy what is the sleep mode current of ATSAM4LS2AA-MU SAM4L low power microcontroller 90uA/MHz ATSAM4LS2AA-MU USB device microcontroller

Related Components & Terms

Microchip Technology Atmel ATSAM4LS2AA-MU ATSAM4LS4AA-MU ATSAM4LC2AA-MU ATSAM3N4AA-MU SAM4L ARM Cortex-M4 Cortex-M3 microcontroller flash microcontroller QFN 48-QFN (7x7 mm) surface mount USB device Peripheral Event System SleepWalking capacitive touch RoHS 90 uA/MHz sleep mode current battery-powered IoT smart metering industrial temperature DSP instructions
Quick Quote RFQ
Fill in complete details — our sales team will respond within 24 hours
Part Number Manufacturer Package QTY Target Price Extended
Total: $0.00 USD
Quote submitted!

We will respond to your email within 24 hours

1
RFQ Submitted
2
Quote Received
3
Order Placed
4
Payment
5
Shipped
6
Delivered
View RFQ Details