Microchip Technology

ATSAM4LS4AA-MU - 48MHz Cortex-M4 256KB Flash MCU | Microchip

MPN: ATSAM4LS4AA-MU ✓ Active
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90 uA/MHz Id 48-QFN (7x7 mm) Package 48 MHz Speed 256 KB (256K x 8) Memory
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Price updated: 2026-09-19
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Qty Unit Price Extended
1 $5.9 $5.90
10 $5.31 $53.10
100 $4.72 $472.00
500 $4.25 $2,125.00
1,000 $3.95 $3,950.00
ℹ️ All prices are in USD

ATSAM4LS4AA-MU Overview

The Microchip Technology ATSAM4LS4AA-MU is a 32-bit ARM Cortex-M4 flash microcontroller running at 48 MHz with 256 KB of embedded Flash memory, housed in a 48-pin QFN (7x7 mm) surface-mount package. It belongs to the SAM4L family, which Microchip (formerly Atmel) positions as the lowest-power Cortex-M4 MCU family, delivering 90 uA/MHz in active mode, 1.5 uA in sleep mode, and wake-up times down to 1.5 us.

A microcontroller unit (MCU) is a single integrated circuit that combines a processor core, memory, and programmable peripherals into one chip, forming the lowest layer of the embedded systems hierarchy: MCU -> embedded processor -> microprocessor-based system. MCUs execute deterministic control and sensing tasks in devices where power budget, cost, and integration matter more than raw throughput.

Key features of the ATSAM4LS4AA-MU include the ARM Cortex-M4 core with 32-bit instruction set at up to 48 MHz, 256 KB (256K x 8) of embedded Flash for code storage, an integrated USB device controller, a peripheral event system that routes signals between peripherals without CPU intervention, and the SleepWalking feature that lets peripherals wake the device based on events while RAM and peripheral state are retained.

Technically, the SAM4L architecture pairs the Cortex-M4 pipeline with a low-leakage process and a flexible power management scheme with multiple sleep modes. The peripheral event system and SleepWalking offload the CPU, so the core can stay in deep sleep while peripherals such as ADC, timers, and communication blocks continue operating, dramatically reducing average system current in duty-cycled designs.

Typical applications include battery-powered portable instruments, sensor nodes and IoT endpoints, and consumer or industrial devices requiring USB connectivity with long battery life. The 48 MHz Cortex-M4 with DSP instructions also handles modest digital filtering and control loops efficiently.

For design, minimize active-mode time by exploiting sleep modes and the event system, and verify the exact pinout and peripheral multiplexing from the Microchip SAM4L datasheet before layout, since QFN packages require careful thermal pad soldering.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for ATSAM4LS4AA-MU — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAM4LS4AA-MU (same form factor and footprint) — differing in RoHS Status, Package, Packaging, Flash Memory, Series.

Microchip Technology
RoHS Status: Compliant (lead-free MU suffix)
Packaging: Tray
Compare with ATSAM4LS4AA-MU →
Microchip Technology
Package: 48-QFN (7x7 mm) with exposed pad
Packaging: Tape & Reel (MRL A)
Flash Memory: 256KB (256K x 8)
Compare with ATSAM4LS4AA-MU →
Microchip Technology
RoHS Status: Compliant
Package: 64-ball WLCSP (5.27 x 5.19 mm)
Packaging: Tape & Reel (T&R)
Compare with ATSAM4LS4AA-MU →
Microchip Technology
RoHS Status: Compliant (GREEN package per Mouser listing)
Package: 48-QFN (7x7 mm) with exposed pad
Packaging: Tray (MRL A per Mouser)
Compare with ATSAM4LS4AA-MU →
Microchip Technology
RoHS Status: Green / Compliant
Package: 48-QFN (7x7 mm) Exposed Pad
Packaging: Tape & Reel (MRL A, T&R)
Compare with ATSAM4LS4AA-MU →
Microchip Technology
RoHS Status: Compliant (Green package)
Package: 48-QFN (7x7 mm) with Exposed Pad
Packaging: Tape & Reel (MRL A)
Compare with ATSAM4LS4AA-MU →
Microchip Technology
RoHS Status: Compliant (GREEN per Mouser listing)
Package: 64-QFN (9x9 mm)
Compare with ATSAM4LS4AA-MU →
Microchip Technology
Package: 48-QFN (7x7 mm)
Compare with ATSAM4LS4AA-MU →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAM4LS4AA-AUR

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7)
ARM Cortex-M4 · 32-bit · 48 MHz · 256KB (256K x 8) · Flash · 1.8V / 3.3V · 48 · 48-TQFP (7x7 mm)

✓ In Stock

$3.98 / Unit

View Datasheet →

ATSAM4LS2AA-MU

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7)
ARM Cortex-M4 · 32-bit · 48 MHz · 128 KB (128K x 8) · 32 KB · 3.3 V nominal · 90 uA/MHz · 1.5 uA

✓ In Stock

$3.55 / Unit

View Datasheet →

ATSAM4LC8BA-UUR

✅ Drop-In
Microchip Technology
📦 48-UQFN (7x7)
ARM Cortex-M4 · 32-bit · 48 MHz · 512 KB · 1.68 V to 3.6 V · 90 uA/MHz · 1.5 uA · 1.5 us (minimum)

✓ In Stock

$3.95 / Unit

View Datasheet →

ATSAM3N4AA-MU

✅ Drop-In
Microchip Technology
📦 48-QFN
ARM Cortex-M3 revision 2.0 · 32-bit · 48 MHz · 256 KB (256K x 8) · FLASH · 24 KB (24K x 8) · 34 · 1.62 V to 3.6 V

✓ In Stock

$4.1 / Unit

View Datasheet →

ATSAM3N4BA-MU

✅ Drop-In
Microchip Technology
📦 48-QFN
ARM Cortex-M3 revision 2.0 · 32-bit · 48 MHz · 256KB (256K x 8) · 24K x 8 · 47 · 1.8 V to 3.3 V · Internal

✓ In Stock

$3.48 / Unit

View Datasheet →

ATSAM4LS4AA-MU Maximum Ratings & Electrical Characteristics

Core Processor ARM Cortex-M4
Core Size 32-Bit
Maximum Clock Speed 48 MHz
Flash Memory 256 KB (256K x 8)
Active Mode Current 90 uA/MHz
Sleep Mode Current 1.5 uA
Wake-up Time down to 1.5 us
USB USB device
Peripheral Features Peripheral event system, SleepWalking
Package 48-QFN (7x7 mm)
Mounting Type Surface Mount
Temperature Grade Industrial
Series SAM4L

ATSAM4LS4AA-MU 48-qfn (7x7 mm) Pin Configuration Guide

Pin configuration for ATSAM4LS4AA-MU (48-qfn (7x7 mm) package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

48-qfn (7x7 mm) package pinout diagram for ATSAM4LS4AA-MU

No detailed pinout data available for ATSAM4LS4AA-MU.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4LS4AA-MU is suitable for 6 applications: Battery-Powered Portable Instruments, IoT Sensor Nodes and Endpoints, USB Peripherals and HID Devices, Industrial Control and Automation Nodes, Wearable and Health Monitoring Devices, Consumer Appliances with USB Interface.

📱

Battery-Powered Portable Instruments

The ATSAM4LS4AA-MU fits portable instruments because its 90 uA/MHz active current and 1.5 uA sleep current directly translate into longer battery runtimes than standard Cortex-M4 MCUs. In a handheld meter, the Cortex-M4 core executes measurement algorithms and DSP filtering at 48 MHz only during short active windows, then enters sleep where the SAM4L draws just 1.5 uA. The 1.5 us wake-up time means button presses or sensor events are serviced with no perceptible latency, so designers do not have to trade responsiveness for battery life. With 256 KB of Flash, calibration tables, GUI assets, and a bootloader fit without external memory. Placed on a coin-cell or single-cell Li-ion design with a low-Iq LDO, the MCU becomes the dominant load only during measurements, enabling multi-year service intervals. Source: Microchip SAM4L product data.

🧩

IoT Sensor Nodes and Endpoints

For IoT sensor nodes, the ATSAM4LS4AA-MU offers the SleepWalking feature and peripheral event system, which let ADC conversions, timer captures, and communication framing proceed while the Cortex-M4 core remains asleep at approximately 1.5 uA. A node can sample a sensor on a timer event, threshold-compare it in a peripheral, and wake the CPU only for radio transmission, cutting average current from milliamps to microamps. The 256 KB Flash accommodates a full TCP/IP or LoRaWAN-style stack plus OTA update double-banking. The integrated USB device port provides factory programming and diagnostics without an external interface chip. Combined with a sub-GHz or BLE radio module and a low-leakage regulator, the SAM4L's 1.5 us wake-up ensures the radio scheduling stays precise while energy harvesters or small cells keep the node alive for years.

🖥️

USB Peripherals and HID Devices

The ATSAM4LS4AA-MU integrates a USB device controller, making it a strong fit for HID devices, sensor dongles, and USB-powered instruments that must enumerate as a peripheral on a PC. Because the controller is on-chip, no external USB interface IC is required, saving board area and BOM cost in the 7x7 mm QFN footprint. The 48 MHz Cortex-M4 provides enough headroom to service USB interrupts, run application logic, and process endpoint data concurrently, while the 256 KB Flash hosts descriptors, class drivers, and the application. In bus-powered designs, the SAM4L's low sleep current keeps standby draw within USB suspend budget limits, and the 1.5 us wake-up allows rapid recovery from suspend when host traffic resumes. Firmware upgrade over USB (bootloader in Flash) simplifies field updates. Source: Microchip ATSAM4LS4A product page.

🏭

Industrial Control and Automation Nodes

In industrial automation nodes, the ATSAM4LS4AA-MU provides a 32-bit Cortex-M4 with DSP-capable arithmetic at 48 MHz for control loops such as PID regulation of motors, valves, and actuators, while its industrial temperature grade suits cabinets and field enclosures. The peripheral event system routes timer and comparator events to peripherals without CPU intervention, giving deterministic response to fast faults even if the firmware is servicing slower communication tasks. The 256 KB Flash holds protocol stacks such as Modbus alongside the control application. SleepWalking supports periodically waking sensor-polling nodes from deep sleep, reducing cable-powered system energy budgets in battery-backup scenarios. Designers should implement robust ESD and transient protection on field-wired I/O and verify the SAM4L peripheral multiplexing from the datasheet pinout tables before committing the PCB.

💊

Wearable and Health Monitoring Devices

Wearable health monitors benefit directly from the ATSAM4LS4AA-MU's power profile: 90 uA/MHz active, 1.5 uA sleep, and 1.5 us wake-up allow continuous low-rate physiological sampling with the CPU asleep between samples. The Cortex-M4's DSP instructions accelerate heart-rate or motion algorithms when bursts of processing are needed at 48 MHz, and the peripheral event system can pre-filter sensor streams in hardware. The 256 KB Flash accommodates signal-processing libraries and BLE-stack companions in a small code footprint. The 48-QFN 7x7 mm package suits compact, low-profile wearable PCBs, and the industrial temperature range covers body-worn environmental extremes. Pairing the MCU with ultra-low-power analog front ends and a small Li-Po cell yields multi-day battery life, and the USB device port enables charging-and-sync docking without additional controllers.

📺

Consumer Appliances with USB Interface

Consumer appliances that need a control MCU plus USB connectivity - coffee machines, chargers, small displays, accessories - can use the ATSAM4LS4AA-MU as a single-chip solution. The integrated USB device controller handles PC or charger enumeration, while the 48 MHz Cortex-M4 runs the appliance state machine, user interface timing, and safety supervision. The 256 KB Flash is ample for menu-driven UIs, fonts, and firmware-update bootloaders, avoiding external memory. Because consumer products spend most of their life in standby, the SAM4L's 1.5 uA sleep current supports low standby-power regulatory targets, and the 1.5 us wake-up keeps button and touch response instant. Designers should decouple the USB VBUS line properly and confirm QFN thermal-pad soldering for reliability. Source: Microchip SAM4L family data.

Recommended Products Summary

MCP1700 Low-quiescent-current LDO for battery rail Used in: Battery-Powered Portable Instruments MCP9808 Precision I2C temperature sensor Used in: Battery-Powered Portable Instruments RN4871 BLE module for wireless connectivity Used in: IoT Sensor Nodes and Endpoints MCP3421 18-bit delta-sigma ADC for sensor front end Used in: IoT Sensor Nodes and Endpoints USB3320 External USB PHY option for ULPI designs Used in: USB Peripherals and HID Devices MCP2200 USB-UART bridge for debug console Used in: USB Peripherals and HID Devices MCP2515 CAN controller via SPI for industrial bus Used in: Industrial Control and Automation Nodes MCP3204 12-bit SPI ADC for analog sensor inputs Used in: Industrial Control and Automation Nodes MCP9700A Low-power analog temperature sensor Used in: Wearable and Health Monitoring Devices MCP3911 Analog front end for precision biosignals Used in: Wearable and Health Monitoring Devices MCP23017 I2C GPIO expander for keypad/LEDs Used in: Consumer Appliances with USB Interface MCP4131 Digital potentiometer for user controls Used in: Consumer Appliances with USB Interface
What are the key specifications of ATSAM4LS4AA-MU that engineers should know?
The ATSAM4LS4AA-MU is a Microchip SAM4L microcontroller with an ARM Cortex-M4 32-bit core running at 48 MHz, 256 KB of embedded Flash, and a USB device controller, packaged in a 48-pin QFN measuring 7x7 mm. Its headline figures are ultra-low power: 90 uA/MHz active current, 1.5 uA sleep current, and wake-up down to 1.5 us. It also provides a peripheral event system and SleepWalking. Source: Microchip ATSAM4LS4A product page.
What is the operating current of ATSAM4LS4AA-MU?
The ATSAM4LS4AA-MU draws 90 uA/MHz in active mode and 1.5 uA in sleep mode, according to the Microchip ATSAM4LS4A product page. Microchip states these are the lowest active-mode and sleep-mode figures available in any Cortex-M4 device, and the shortest wake-up time of 1.5 us further reduces average current in duty-cycled battery applications.
What is the difference between ATSAM4LS4AA-MU and ATSAM4LS2AA-MU?
The primary difference is Flash memory: the ATSAM4LS4AA-MU provides 256 KB while the ATSAM4LS2AA-MU provides 128 KB, roughly half the code storage. Both are SAM4L Cortex-M4 parts in the same 48-pin QFN 7x7 mm footprint with the same 48 MHz core and low-power features, so the LS2AA can serve as a drop-in option when the application fits within 128 KB, with re-verification of pin compatibility recommended against the datasheet.
What is the best drop-in replacement for ATSAM4LS4AA-MU?
The closest drop-in replacement is ATSAM4LS4AA-AUR, the identical die in the same 48-QFN package qualified for extended automotive temperature range, requiring no PCB change. For cost-optimized designs with less code, ATSAM4LS2AA-MU shares the SAM4L 48-QFN footprint with 128 KB Flash. Always verify the exact pinout and peripheral multiplexing in the Microchip SAM4L datasheet before qualifying any substitution.
Can ATSAM3N4AA-MU replace ATSAM4LS4AA-MU?
Only partially. The ATSAM3N4AA-MU is a SAM3N Cortex-M3 part in a 48-QFN package, so it offers a similar footprint class, but it runs a Cortex-M3 core rather than the Cortex-M4, lacks the DSP instructions and the SAM4L SleepWalking and peripheral event system, and differs in Flash organization. It is a last-resort alternative when SAM4L parts are unavailable, and it requires full firmware revalidation, not a firmware-identical swap.
When should I choose ATSAM4LS4AA-MU over ATSAM4LS2AA-MU?
Choose the ATSAM4LS4AA-MU when your firmware image, bootloader, OTA update slots, or data logging needs exceed 128 KB, since it provides 256 KB of Flash in the same package. Choose the ATSAM4LS2AA-MU when the code fits in 128 KB and unit cost matters, as smaller-Flash siblings are typically cheaper. Both share the 48 MHz Cortex-M4, USB device, event system, and the 7x7 mm 48-QFN footprint, so migration between them is a BOM-level change, not a redesign.
Is ATSAM4LS4AA-MU suitable for battery-powered IoT sensor nodes?
Yes, it is explicitly targeted at battery applications. According to Microchip, the SAM4L family achieves 90 uA/MHz active current, 1.5 uA sleep current, and 1.5 us wake-up, which are class-leading Cortex-M4 figures. Combined with the SleepWalking feature and the peripheral event system, peripherals can gather and process sensor data while the CPU stays asleep, extending battery life in duty-cycled sensor nodes.
Where to download the ATSAM4LS4AA-MU datasheet PDF?
Download the ATSAM4LS4AA-MU datasheet PDF from the official Microchip product page at microchip.com/en-us/product/ATSAM4LS4A, which links the current SAM4L family datasheet covering this device. Third-party mirrors such as datasheetq.com also host the Atmel-era PDF, but the Microchip site guarantees the latest revision. The datasheet includes pinouts, electrical characteristics, and register descriptions needed for hardware and firmware design.
Where can I find the ATSAM4LS4AA-MU pinout?
The complete 48-pin QFN pinout for the ATSAM4LS4AA-MU is documented in the pinout and signal multiplexing tables of the Microchip SAM4L family datasheet, accessible from the official ATSAM4LS4A product page. Because SAM4L pins are heavily multiplexed across GPIO, communication, and analog functions, always confirm the peripheral-to-pin mapping for your configuration in the datasheet rather than relying on simplified diagrams, and note the exposed pad grounding requirements.
What is the price of ATSAM4LS4AA-MU?
XAIPART lists the ATSAM4LS4AA-MU from approximately $5.90 at quantity 1, stepping down to about $3.95 at 1,000 units, as of 2026-09-20. Actual distributor pricing on DigiKey, Mouser, and Octopart aggregated from around 10 distributors varies with stock levels, so request a quote for volume pricing and confirm current inventory before ordering production quantities.
Where to buy ATSAM4LS4AA-MU online?
You can buy the ATSAM4LS4AA-MU from XAIPART directly, or compare stock across authorized distributors: DigiKey (digikey.sg, part 3900212), Mouser, Octopart-listed suppliers (about 9-10 distributors aggregate there), and secondary sources such as Fusion Worldwide and Xecor. For production volumes, request quotes from multiple sources since stock and lead time fluctuate; XAIPART provides immediate RFQ handling.
Is ATSAM4LS4AA-MU in stock and what is the lead time?
Stock for the ATSAM4LS4AA-MU changes frequently: Octopart reports around 2,125 units historically available across distributors, and DigiKey typically ships same-day for in-stock line items. Lead time when distributors are dry is typically quoted through Microchip or franchise channels and can extend to many weeks, so verify real-time inventory on DigiKey or Mouser, or submit an RFQ to XAIPART for current allocation, as of 2026-09-20.
What is the best NXP or ST equivalent for ATSAM4LS4AA-MU?
A single cross-brand, pin-to-pin equivalent for the ATSAM4LS4AA-MU 48-QFN does not exist in verified cross-reference data, since QFN-48 MCU pinouts are vendor-specific. Functionally comparable ultra-low-power Cortex-M4 parts include STMicroelectronics STM32L4 series and NXP LPC5411x series, but they require PCB redesign. For footprint-preserving replacement, stay within the Microchip SAM4L family; cross-brand migration should be treated as a new hardware design. Source: web cross-reference searches, 2026-09-20.
Is ATSAM4LS4AA-MU the same as ATSAM4LS4AA-AUR?
They are the same silicon die and package but different temperature qualifications: the -MU suffix is the industrial-grade part, while the -AUR suffix is qualified for extended automotive temperature range. Both use the 48-pin QFN 7x7 mm footprint, 256 KB Flash, and identical peripherals, so the AUR can physically replace the MU in most cases, though the automotive version typically carries a price premium and different ordering data. Verify ordering codes against the current Microchip catalog.
Does the ATSAM4LS4AA-MU support USB?
Yes. According to the Microchip ATSAM4LS4A product page, the device features an integrated USB device controller, allowing the MCU to enumerate as a USB peripheral for applications such as virtual COM ports, HID devices, and firmware update paths. This removes the need for an external USB interface chip and, combined with the low 90 uA/MHz active current, suits USB-powered battery-charged designs.
What is SleepWalking on the ATSAM4LS4AA-MU?
SleepWalking is a Microchip SAM4L power-saving feature that allows peripherals to operate and react to events while the CPU core remains in a low-power sleep state. Because the core wakes only when genuine processing is needed, average system current drops dramatically compared with periodic polling. Together with the peripheral event system, which routes signals between peripherals without CPU intervention, it enables sensor acquisition, communication, and timing tasks at sleep-level currents of around 1.5 uA.

Engineering reference data for ATSAM4LS4AA-MU — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4LS4AA-MU when you need a 48 MHz Cortex-M4 with 256 KB Flash, USB device, and class-leading battery figures (90 uA/MHz, 1.5 uA sleep, 1.5 us wake-up) in a compact 48-QFN 7x7 mm package - ideal for battery instruments, IoT nodes, and USB peripherals. Choose ATSAM4LS2AA-MU instead if your application fits in 128 KB and cost dominates; it is footprint-identical. Choose ATSAM4LS4AA-AUR for extended/automotive temperature environments - same silicon, higher price. Only fall back to ATSAM3N4AA-MU or ATSAM3N4BA-MU when SAM4L parts are unavailable: they are Cortex-M3 parts without USB, SleepWalking, or the event system, so expect firmware rework, higher power, and possible PCB changes. Honest trade-off: no verified cross-brand pin-to-pin equivalent exists in a 48-QFN, so staying within Microchip SAM4L/SAM3N families preserves your footprint.

Comparison with Alternatives

Parameter This Product ATSAM4LS4AA-AUR ATSAM4LS2AA-MU ATSAM4LC8BA-UUR ATSAM3N4AA-MU ATSAM3N4BA-MU
Package 48-QFN (7x7 mm) 48-QFN (7x7 mm) - same 48-QFN (7x7 mm) - same 48-UQFN (7x7 mm) - near-same 48-QFN - same class 48-QFN - same class
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core / Series ARM Cortex-M4 (SAM4L) ARM Cortex-M4 (SAM4L) ARM Cortex-M4 (SAM4L) ARM Cortex-M4 (SAM4L, LC variant) ARM Cortex-M3 (SAM3N) ARM Cortex-M3 (SAM3N)
Max Clock Speed 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
SleepWalking / Event System Yes Yes Yes Yes No No
USB Device Yes Yes Yes Yes No (SAM3N has no USB) No (SAM3N has no USB)
Temperature Grade Industrial Automotive / extended Industrial Industrial Industrial Industrial

Key Differentiators

  • Class-leading low power in a Cortex-M4 (vs ATSAM3N4AA-MU)
  • Double the Flash of the cost-optimized sibling (vs ATSAM4LS2AA-MU)
  • Integrated USB device controller (vs ATSAM3N4BA-MU)
  • Automotive-qualified drop-in option (vs ATSAM4LS4AA-AUR)

Design Notes

Exploit the SAM4L low-power architecture to its full extent: schedule work so the Cortex-M4 core runs at 48 MHz in short bursts (at 90 uA/MHz) and sleeps at 1.5 uA the rest of the time. Use the SleepWalking feature so peripherals wake on events without core involvement, and route simple signal routing through the peripheral event system instead of CPU interrupts. Estimated: a node that is active 1% of the time at ~4.3 mA (48 MHz) and sleeping at 1.5 uA yields an average current near 45 uA - multi-year life on a 1000 mAh cell. Always measure your actual firmware, since peripheral leakage dominates in deep sleep.

The 48-QFN (7x7 mm) package has a small pitch and an exposed pad; design the land pattern per the Microchip SAM4L datasheet and provide a via-fanout array under the exposed pad to ground for both thermal and electrical performance. Place 100 nF decoupling capacitors within 2-3 mm of each supply pin, one bulk capacitor per rail, and keep the USB D+/D- differential pair 90 ohm matched if the USB device port is used. Confirm the peripheral-to-pin multiplexing for your exact configuration in the datasheet pinout tables before routing, because SAM4L functions are heavily multiplexed across the 48 pins.

Do not assume firmware compatibility across SAM generations: the SAM3N alternatives (ATSAM3N4AA-MU / ATSAM3N4BA-MU) are Cortex-M3 parts without the SAM4L event system, SleepWalking, or USB device, so code ported to them will lose low-power and USB behavior. When substituting ATSAM4LS2AA-MU, verify the compiled image plus bootloader fits in 128 KB Flash with margin for OTA double-banking. Also confirm exact ordering-code suffixes (-MU industrial vs -AUR extended temperature) match your environmental requirements, and validate supply voltage against the current datasheet revision rather than legacy Atmel documents.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Unknown

Mouser listing references GREEN,IND TEMP,MRL A packaging for this device; formal RoHS/REACH declarations were not present in the provided data - consult the Microchip product page for current environmental certificates.

Data verified on: 2026-09-20 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology Atmel Corporation ATSAM4LS4AA-MU ATSAM4LS4A ATSAM4LS2AA-MU ATSAM4LS4AA-AUR ATSAM4LC8BA-UUR ATSAM3N4AA-MU ARM Cortex-M4 ARM Cortex-M3 SAM4L SAM3N microcontroller embedded microcontroller IC 48-QFN (7x7 mm) QFN package family surface mount SleepWalking peripheral event system USB device controller 256 KB Flash 90 uA/MHz industrial temperature grade IoT sensor node battery-powered portable device
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