Microchip Technology

ATSAM4S16CA-ANR - Cortex-M4 MCU 120MHz 1MB Flash | Microchip

MPN: ATSAM4S16CA-ANR βœ“ Active
In Stock Ships in 1-3 business days
1.62 V to 3.6 V Vdss 100-LQFP (14x14 mm) Package 120 MHz Speed 1 MB (1024 KB, dual-bank, with ECC) Memory
From $5.95 USD / Unit
MOQ: 1 |
Price updated: 2026-09-20
Volume Pricing
Qty Unit Price Extended
1 $7.46 $7.46
10 $7.19 $71.90
100 $6.75 $675.00
500 $6.38 $3,190.00
1,000 $5.95 $5,950.00
ℹ️ All prices are in USD

ATSAM4S16CA-ANR Overview

The Microchip Technology ATSAM4S16CA-ANR is a 32-bit ARM Cortex-M4 microcontroller with a maximum operating frequency of 120 MHz, 1 MB (1024 KB) dual-bank embedded Flash with ECC, and 128 KB of SRAM, housed in a 100-pin LQFP (14x14 mm) package.

A microcontroller (MCU) is a single-chip embedded computer that integrates a processor core, program memory, data memory, and peripherals on one die. Within the power-management hierarchy of embedded systems, general-purpose MCUs like the SAM4S family form the central control layer, executing application firmware while driving communication, sensing, and actuation peripherals.

Key features include the Cortex-M4 core with DSP instructions and Thumb-2 instruction set, a Memory Protection Unit (MPU), dual-bank Flash supporting safe in-application programming, and a Security Bit plus Flash lock for IP protection. According to Microchip, power consumption is 200 uA/MHz, and the supply range of 1.62V to 3.6V enables battery and 3.3V industrial designs.

The SAM4S16 architecture pairs the Cortex-M4 with a multi-layer bus matrix, DMA-capable peripherals such as UART, USART, SPI, I2C/TWI, and a 12-bit ADC, sustaining deterministic real-time behavior for control loops while DSP instructions accelerate filtering and math-intensive routines. The parallel input/output (PIO) data-capture mode supports high-throughput digital acquisition.

Typical applications include industrial automation controllers, smart energy metering, portable/battery-powered devices, and consumer/POS equipment, where the combination of 120 MHz performance, low power, and rich connectivity fits cost-sensitive designs.

Design consideration: the SAM4S series is pin-to-pin compatible with SAM3N, SAM3S, SAM4N, and legacy SAM7S (64-pin versions), so layouts can be upgraded without PCB rework; validate VDDIO levels when migrating from 5V-tolerant legacy parts.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for ATSAM4S16CA-ANR β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAM4S16CA-ANR (same form factor and footprint) β€” differing in RoHS Status, Package, Flash Memory, Instruction Set, Packaging.

Microchip Technology
RoHS Status: Green (per Mouser listing)
Flash Memory: 1 MB (1024 Kbytes)
Packaging: Tape & Reel (T&R)
Compare with ATSAM4S16CA-ANR β†’
Microchip Technology
RoHS Status: Green / RoHS compliant (per Mouser listing)
Package: 100-VFBGA (7x7 mm)
Instruction Set: Thumb-2, DSP instructions
Compare with ATSAM4S16CA-ANR β†’
Microchip Technology
RoHS Status: Compliant (Green package per Mouser: LQFP, GREEN, IND TEMP)
Package: 100-LQFP (14 x 14 mm)
Flash Memory: 1 MB (1M x 8)
Compare with ATSAM4S16CA-ANR β†’

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

ATSAM4S16CA-CFNR

βœ… Drop-In
πŸ“¦ 100-LQFP (14x14 mm)
same die and 1 MB Flash, different temperature/speed ordering code (CFN vs ANR), pin-to-pin compatible

πŸ“‹ Reference alternative (not in catalog)

ATSAM4S16CB-ANR

βœ… Drop-In
πŸ“¦ 100-LQFP (14x14 mm)
Flash doubled to 2 MB vs 1 MB (+100%), same 120 MHz Cortex-M4 and pinout

πŸ“‹ Reference alternative (not in catalog)

ATSAM4SA16CA-ANR

βœ… Drop-In
πŸ“¦ 100-LQFP (14x14 mm)
same 1 MB Flash SAM4S die with picoPower enhancements, pin-to-pin compatible

πŸ“‹ Reference alternative (not in catalog)

ATSAM4E16CA-ANR

βœ… Drop-In
πŸ“¦ 100-LQFP (14x14 mm)
same 1024 KB Flash and 100-pin LQFP footprint, but SAM4E core adds Ethernet MAC; peripheral mux differs

πŸ“‹ Reference alternative (not in catalog)

ATSAM4N16CA-CFUR

βœ… Drop-In
Microchip Technology
πŸ“¦ 100-LQFP (14x14 mm)
ARM Cortex-M4 Β· 32-Bit Single-Core Β· 100 MHz Β· 1 MB (1M x 8) Β· 80 KB Β· 1.62 V to 3.6 V Β· Thumb-2, DSP instructions Β· Yes (MPU)

βœ“ In Stock

$4.95 / Unit

View Datasheet β†’

ATSAM4S16CA-AU

βœ… Drop-In
Microchip Technology
πŸ“¦ 100-LQFP (14x14 mm)
ARM Cortex-M4 Β· 32-bit Β· 120 MHz Β· 1 MB (1M x 8) Β· 128 KB Β· 2 Kbytes Β· Yes (MPU) Β· Yes

βœ“ In Stock

$5.55 / Unit

View Datasheet β†’

ATSAM4S16CA-ANR Maximum Ratings & Electrical Characteristics

Core ARM Cortex-M4
Core Size 32-bit
Maximum Clock Frequency 120 MHz
Flash Memory 1 MB (1024 KB, dual-bank, with ECC)
SRAM 128 KB
Supply Voltage Range 1.62 V to 3.6 V
Power Consumption 200 uA/MHz
Instruction Set Thumb-2 with DSP instructions
Memory Protection Unit Yes (MPU)
Security Security Bit and Flash lock
Package 100-LQFP (14x14 mm)
Mounting Type Surface Mount
Temperature Grade Industrial
Terminal Form Gull Wing
Packaging Tape & Reel (T/R)
Pin Compatibility SAM3N, SAM3S, SAM4N, SAM7S (64-pin versions for SAM7S)
RoHS Status Compliant (LQFP GREEN)

ATSAM4S16CA-ANR 100-lqfp (14x14 mm) Pin Configuration Guide

Pin configuration for ATSAM4S16CA-ANR (100-lqfp (14x14 mm) package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

100-lqfp (14x14 mm) package pinout diagram for ATSAM4S16CA-ANR

No detailed pinout data available for ATSAM4S16CA-ANR.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4S16CA-ANR is suitable for 6 applications: Industrial Automation Controllers, Smart Energy Metering, Portable and Battery-Powered Devices, IoT Sensor Nodes, Consumer and POS Equipment, Motor Control and Embedded Systems.

🏭

Industrial Automation Controllers

The ATSAM4S16CA-ANR fits industrial control nodes where deterministic 120 MHz Cortex-M4 execution, 1 MB dual-bank Flash for field-updatable firmware, and ECC-protected program memory matter. Industrial-temperature qualification (-AN suffix) supports factory-floor environments, while 3.3V operation simplifies integration with PLC I/O. DMA-driven USART, SPI, and TWI peripherals offload the core for Modbus/RTU communication and sensor polling, and the PIO capture mode acquires parallel digital streams without CPU overhead.

⚑

Smart Energy Metering

Metering designs exploit the 200 uA/MHz efficiency and 1.62V-3.6V supply of the ATSAM4S16CA-ANR for always-on metrology front ends. The Cortex-M4 DSP instructions (single-cycle MAC, SIMD) accelerate FFT and RMS energy calculations, while the 12-bit ADC samples voltage/current channels. Dual-bank Flash with ECC permits secure firmware updates in the field, and the Security Bit plus Flash lock protect calibration tables and billing IP from unauthorized readout.

πŸ“±

Portable and Battery-Powered Devices

Handheld instruments, data loggers, and POS terminals benefit from the ATSAM4S16CA-ANR balance of 120 MHz responsiveness and 200 uA/MHz consumption. The 1.62V low end of the supply range allows direct operation from Li-ion cell stacks via simple regulation, and wait/sleep modes cut average current between user interactions. USB device connectivity on the SAM4S family handles charging status reporting and PC communication, while 128 KB SRAM buffers logging data during offline periods.

🧩

IoT Sensor Nodes

The ATSAM4S16CA-ANR serves as the local processing hub in IoT nodes, aggregating ADC sensor channels and pushing data over SPI/UART-connected radio modules. DSP instructions run local filtering and anomaly detection before transmission, reducing radio duty cycle and battery load. The MPU enables task isolation in RTOS-based nodes, and 1 MB Flash accommodates OTA-update stacks such as dual-image bootloader schemes, making the part a robust choice for industrial sensing gateways.

πŸ”§

Consumer and POS Equipment

Point-of-sale terminals, barcode scanners, and consumer appliances use the ATSAM4S16CA-ANR for its USB device interface, responsive 120 MHz core, and cost-effective 100-pin LQFP integration. The Thumb-2 code density keeps firmware compact within 1 MB Flash, Flash lock protects payment-related code, and gull-wing surface-mount terminals support high-volume assembly. Pin compatibility with SAM3S lets consumer platforms reuse proven PCB footprints across product generations.

βš™

Motor Control and Embedded Systems

Low- to mid-power motor drives use the ATSAM4S16CA-ANR to execute FOC control loops, with Cortex-M4 DSP instructions computing Park/Clarke transforms within PWM periods. PWM peripherals generate complementary drive signals while the ADC synchronizes current sampling, and the 120 MHz core leaves margin for supervisory logic and communication. The industrial temperature rating and ECC Flash ensure reliability in continuous-duty embedded systems such as pumps, fans, and robotics axes.

Recommended Products Summary

ATSAM4E16CA-ANR Ethernet-enabled sibling for networked controllers Used in: Industrial Automation Controllers, Motor Control and Embedded Systems ATSAM4N16CA-CFUR Microchip Technology Used in: Industrial Automation Controllers, IoT Sensor Nodes ATSAM4SA16CA-ANR picoPower variant for battery-backed meters Used in: Smart Energy Metering, Portable and Battery-Powered Devices ATSAM4S16CB-ANR 2 MB Flash upgrade for feature-rich consumer firmware Used in: Consumer and POS Equipment
What are the key specifications of ATSAM4S16CA-ANR that engineers should know?
The Microchip ATSAM4S16CA-ANR is an ARM Cortex-M4 32-bit microcontroller running at up to 120 MHz with 1 MB dual-bank Flash (with ECC), 128 KB SRAM, and a 1.62V to 3.6V supply. It draws 200 uA/MHz, includes an MPU, DSP instructions, a Security Bit, and comes in a 100-pin 14x14 mm LQFP industrial-temperature package. Source: Microchip ATSAM4S16C product page.
What is the price of ATSAM4S16CA-ANR?
The ATSAM4S16CA-ANR unit price is approximately $7.19 at quantity 1, with volume breaks reducing cost toward roughly $5.95 at 1000 pieces as of 2026-09-20. Third-party distributor listings have shown unit prices near $7.19-$7.46. Because spot pricing fluctuates, request a live quote on this page for current XAIPART pricing and stock.
Where to buy ATSAM4S16CA-ANR online?
You can buy the ATSAM4S16CA-ANR from XAIPART directly on this page, or from major distributors such as DigiKey, Mouser, and Octopart-listed suppliers, which currently list the part with in-stock quantities. The product is listed as IC MCU 32BIT 1MB FLASH 100LQFP. For bulk orders, XAIPART offers volume pricing tiers from 1 to 1000+ pieces as of 2026-09-20.
Is ATSAM4S16CA-ANR in stock and what is the lead time?
Availability varies by distributor: several sources report in-stock quantities (e.g., 3,984 pieces at one distributor, up to 45,150 pieces across distributor networks), while others list lead time as to-be-confirmed. DigiKey and Mouser typically ship same-day for stocked line items. Check the live inventory status on this page or request a quote for factory lead time before committing to production schedules.
What is the difference between ATSAM4S16CA-ANR and ATSAM4S16CB-ANR?
Both are SAM4S-family Cortex-M4 microcontrollers in the same 100-pin LQFP package and are pin-to-pin compatible. The key difference is memory: the S16C variant carries 1 MB of Flash, while the S16CB variant doubles the Flash to 2 MB for larger code images. Peripherals, 120 MHz clock, and SRAM architecture remain in the same family, so the CB can substitute when firmware outgrows 1 MB. Source: Microchip SAM4S family documentation.
What is the difference between ATSAM4S16CA-ANR and ATSAM4E16CA-ANR?
The ATSAM4E16CA-ANR belongs to the SAM4E family, which adds an Ethernet MAC and USB-HS PHY support on top of the Cortex-M4 120 MHz core, while the ATSAM4S16CA-ANR is a SAM4S part focused on general-purpose and power-sensitive applications. Both offer 1024 KB Flash and ship in 100-pin LQFP. Choose SAM4E when Ethernet connectivity is required; choose SAM4S for lowest system cost in non-networked designs.
When should I choose ATSAM4S16CA-ANR over ATSAM4N16CA?
Choose the ATSAM4S16CA-ANR when your application needs USB device connectivity, faster Flash programming, or the SAM4S peripheral set; choose the SAM4N when you need the absolute lowest power at lower cost and do not need USB. The SAM4S runs at 120 MHz with 200 uA/MHz and is pin-to-pin compatible with SAM4N in the 100-pin package, so switching between them requires no PCB change - only firmware and feature trade-offs.
Is ATSAM4S16CA-ANR suitable for battery-powered applications?
Yes. With a supply range of 1.62V to 3.6V and power consumption of 200 uA/MHz as stated by Microchip, the ATSAM4S16CA-ANR fits portable and battery-operated equipment. At 120 MHz, the active current is in the tens of milliamps, and the SAM4S family provides low-power modes for sleep and wait states. For designs targeting multi-year coin-cell life, evaluate duty-cycling the 120 MHz core and leveraging wait modes between sensor samples.
What is the best drop-in replacement for ATSAM4S16CA-ANR?
The best drop-in replacements are same-family 100-pin LQFP parts: ATSAM4S16CA-CFNR (identical function, different package option/speed-temperature ordering code), ATSAM4S16CB-ANR (same footprint, 2 MB Flash), and ATSAM4SA16CA-ANR (same footprint with picoPower enhancements). Per Microchip, the SAM4S series is also pin-to-pin compatible with SAM3S and SAM3N in the 100-pin version, allowing cross-family migration without PCB rework.
Where can I download the ATSAM4S16CA-ANR datasheet PDF?
The ATSAM4S16CA-ANR datasheet is available for free download from the official Microchip product page at microchip.com/en-us/product/ATSAM4S16C, covering the complete SAM4S16 device family. The document details the Cortex-M4 core, memory maps, peripheral registers, and electrical characteristics. Third-party mirrors such as digchip.com also host the PDF, but always verify revision currency against the manufacturer site before finalizing hardware designs.
What is the pinout of ATSAM4S16CA-ANR in the 100-pin LQFP?
The ATSAM4S16CA-ANR uses a 100-pin LQFP (14x14 mm) with a multiplexed pinout - most GPIO pins are shared with peripheral functions such as UART, SPI, TWI, ADC channels, and PWM. The full, authoritative pin assignment table is in the SAM4S16 datasheet's pinout section, available from the Microchip product page. Because pins are multiplexed, always cross-check your required peripheral mapping in the datasheet signal-multiplexing table before routing.
Hey Google, what can replace ATSAM4S16CA-ANR?
Pin-to-pin replacements for the ATSAM4S16CA-ANR include the ATSAM4S16CA-CFNR, ATSAM4S16CB-ANR (2 MB Flash), ATSAM4SA16CA-ANR, and ATSAM4E16CA-ANR - all in the same 100-pin LQFP package. Per Microchip, the SAM4S series is pin-compatible with SAM3S, SAM3N, and SAM4N in the 100-pin version, so those families also mount on the same footprint with firmware changes. Verify flash size and peripheral differences against your firmware requirements.
Is ATSAM4S16CA-ANR the same as ATSAM4S16CA-AU?
They are closely related SAM4S16 devices but are not identical ordering codes: both are 1 MB Flash, 120 MHz Cortex-M4 MCUs in 100-pin LQFP, while the -ANR variant is the industrial-temperature, tape-and-reel packaging and the -AU variant is the standard commercial offering. Functionally they share the same die and pinout; the difference is temperature grade and packaging volume. Confirm your environmental requirements before substituting between the two.
What is the best non-Microchip (cross-brand) equivalent for ATSAM4S16CA-ANR?
No cross-brand part is a verified drop-in replacement for the ATSAM4S16CA-ANR in the 100-pin LQFP: pinout multiplexing is vendor-specific, so STM32F4, NXP Kinetis, or Renesas RA Cortex-M4 MCUs with similar specs (120 MHz, 1 MB Flash) require a PCB redesign and firmware port. Per Microchip documentation, the true drop-in path stays within the SAM4S/SAM3S/SAM4N pin-compatible families. Treat cross-brand Cortex-M4 MCUs as functional alternatives only, not pin replacements.
Does ATSAM4S16CA-ANR support DSP and floating-point operations?
The ATSAM4S16CA-ANR is based on the ARM Cortex-M4 core with dedicated DSP instructions and the Thumb-2 instruction set, as stated by Microchip. DSP instructions such as single-cycle MAC and SIMD operations accelerate filtering and control algorithms. Note that the SAM4S16 does not include the Cortex-M4F hardware FPU; single-precision floating point executes in software, so prefer fixed-point math or the built-in DSP instructions in performance-critical loops.
Is ATSAM4S16CA-ANR RoHS compliant?
Yes, the ATSAM4S16CA-ANR is RoHS compliant - Mouser lists the part as LQFP GREEN, indicating lead-free, halogen-conscious green packaging from Microchip. Distributor listings describe it as lead-free surface-mount in 100-pin LQFP with tape-and-reel packaging. For formal compliance documentation (RoHS certificate of conformity, REACH statements), download the current compliance package from the Microchip product page or request it from your distributor.

Engineering reference data for ATSAM4S16CA-ANR β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4S16CA-ANR when you need 120 MHz Cortex-M4 performance, 1 MB ECC Flash, and USB device connectivity in a cost-effective 100-pin LQFP for industrial, metering, or portable designs. Choose the ATSAM4S16CB-ANR if firmware is likely to exceed 1 MB. Choose the ATSAM4SA16CA-ANR for battery products where picoPower standby current dominates. Choose the ATSAM4E16CA-ANR when Ethernet MAC integration eliminates an external controller. Choose the ATSAM4N16CA-CFUR only when USB is unnecessary and lowest power at reduced clock is the priority. All alternatives share the same 100-pin LQFP footprint, enabling PCB reuse, but verify peripheral multiplexing differences and temperature-grade ordering codes before committing a BOM swap. No cross-brand Cortex-M4 MCU is pin-compatible - vendor pinout multiplexing prevents true drop-in substitution outside the Microchip SAM families.

Comparison with Alternatives

Parameter This Product ATSAM4S16CA-CFNR ATSAM4S16CB-ANR ATSAM4E16CA-ANR ATSAM4N16CA-CFUR
Package 100-LQFP (14x14 mm) 100-LQFP - same 100-LQFP - same 100-LQFP - same 100-LQFP - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core / Clock Cortex-M4, 120 MHz Cortex-M4, 120 MHz Cortex-M4, 120 MHz Cortex-M4, 120 MHz Cortex-M4, 100 MHz (lower speed)
Flash 1 MB (dual-bank, ECC) 1 MB 2 MB 1024 KB 1024 KB
Ethernet MAC No No No Yes (SAM4E family) No
USB Device Yes (SAM4S family) Yes Yes Yes (USB HS) No (SAM4N has no USB)
Temperature Grade Industrial (-AN) Industrial (CFN) Industrial (-AN) Industrial (-AN) Industrial (CFU)
Packaging Tape & Reel (R) Tape & Reel Tape & Reel Tape & Reel Tape & Reel

Key Differentiators

  • Larger Flash capacity option in the same footprint (vs ATSAM4S16CB-ANR)
  • USB device connectivity (vs ATSAM4N16CA-CFUR)
  • Lowest power at reduced clock (vs ATSAM4E16CA-ANR)

Design Notes

The ATSAM4S16CA-ANR accepts 1.62V-3.6V on VDDCORE/VDDIO domains. Budget active current as roughly 200 uA/MHz x 120 MHz = approximately 24 mA (Estimated: derived from the Microchip-stated 200 uA/MHz figure at full-speed operation), plus peripheral and I/O loads. Decouple each VDD pin with 100 nF ceramic capacitors placed within 2 mm of the pin, plus bulk 10 uF at the regulator. If powered from a Li-ion cell, use a low-Iq LDO or buck converter to exploit the wide supply range.

The 100-pin LQFP (0.5 mm pitch) requires careful fan-out: use 4-mil traces for breakouts and place the crystal within 10 mm of the XIN/XOUT pins with guard ground. Because the SAM4S is pin-to-pin compatible with SAM3S/SAM4N, design the footprint once and reuse it across family generations - but verify the peripheral multiplexing table when changing devices, since pin functions differ even though ball-for-ball positions match.

Do not assume hardware FPU: the SAM4S16 Cortex-M4 (without F suffix) executes floating point in software. Prefer fixed-point or the built-in DSP instructions for performance-critical loops. Also remember dual-bank Flash: design your bootloader to program the inactive bank and swap banks on reset, so a power failure during update never bricks the unit. Enable the Security Bit only after final validation - it permanently disables boundary-scan debug access.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Unknown

Mouser lists the part as LQFP GREEN (lead-free green packaging). REACH, halogen-free, and conflict-minerals statements should be obtained from Microchip compliance documentation.

Data verified on: 2026-09-20 β€” data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology ATSAM4S16CA-ANR ATSAM4S16CB-ANR ATSAM4E16CA-ANR ATSAM4N16CA-CFUR ATSAM4SA16CA-ANR ARM Cortex-M4 SAM4S series microcontroller embedded microcontroller (MCU) LQFP-100 QFP surface-mount package family Thumb-2 instruction set DSP instructions Memory Protection Unit (MPU) dual-bank Flash with ECC RoHS Tape & Reel industrial automation smart energy metering IoT sensor node power consumption uA/MHz
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