Microchip Technology

PIC18F4220-E/P - 8-Bit 25MHz 4KB Flash MCU 40-PDIP | Microchip

MPN: PIC18F4220-E/P ✓ Active
In Stock Ships in 1-3 business days
4.2 V to 5.5 V Vdss 40-pin PDIP (P) Package 25 MHz (10 MIPS) Speed 4 KB (2K x 16) Memory
From $4.65 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $7.56 $7.56
10 $6.84 $68.40
100 $6.05 $605.00
500 $5.27 $2,635.00
1,000 $4.65 $4,650.00
ℹ️ All prices are in USD

PIC18F4220-E/P Overview

The Microchip Technology PIC18F4220-E/P is a high-performance 8-bit CMOS Flash microcontroller based on the PIC18 architecture, featuring 25 MHz (10 MIPS) operation and packaged in a 40-pin PDIP (0.600 inch, 15.24 mm). The device includes 4 KB Flash program memory (2K x 16), 512 bytes of SRAM, and 256 bytes of EEPROM data memory, delivering a C compiler-friendly development environment with self-programming support.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program memory, RAM, and configurable peripherals into one package. The PIC18 family belongs to Microchip's 8-bit RISC microcontroller hierarchy - an 8-bit MCU -> PIC microcontroller -> PIC18 family -> Flash-based microcontroller -> embedded controller. Within this hierarchy the PIC18F4220 sits in the mid-range tier, balancing program memory, peripheral count, and I/O count for embedded control tasks. The 'E' suffix indicates the Extended industrial temperature grade of -40C to +125C, while the 'P' suffix designates the PDIP-40 package.

Key features of this part include 36 digital I/O pins, 13 channels of 10-bit Analog-to-Digital converter (ADC), 2 analog comparators, 2 Capture/Compare/PWM (CCP) modules, a 10-bit enhanced PWM, a synchronous serial port configurable as SPI or I2C, two 8-bit timers plus one 16-bit timer, a parallel slave port, and an internal oscillator. The instruction set offers only 77 single-word instructions and is upward compatible with PIC16C5X, PIC12CXXX, PIC16CXX and PIC17CXX devices, easing software migration from older Microchip parts.

Typical applications include industrial control, sensor interface, low-power remote controls, appliance controllers, and small embedded data-acquisition nodes. The 10 MIPS performance, broad peripheral mix, and self-programming support make it a strong fit for legacy PIC18 designs and for new designs targeting the PIC18 ecosystem with MPLAB X and XC8 toolchain compatibility.

When designing with this device, place decoupling capacitors as close as possible to the VDD/VSS pins and follow Microchip's MPLAB ICD in-circuit debugging guidelines. The Extended temperature grade (-40C to +125C) allows deployment in automotive, industrial, and outdoor environments without additional qualification.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found on any single manufacturer or distributor page.

Drop-in alternatives for PIC18F4220-E/P — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F4220-E/P (same form factor and footprint) — differing in Package, Timers, Operating Temperature, RoHS Status, Program Memory (Flash).

Microchip Technology
Package: 40-PDIP (0.600", 15.24 mm)
Timers: 2 x 8-bit, 3 x 16-bit
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: 44-pin VQFN (ML) with exposed pad
Timers: 4 (TMR0/TMR1/TMR2/TMR3)
Operating Temperature: -40C to +125C (Extended, "E")
Microchip Technology
Package: 40-pin PDIP (DIP-40)
Timers: 1 x 8-bit, 3 x 16-bit
Operating Temperature: -40C to +85C (Industrial, -I suffix)
Microchip Technology
Package: 44-pin TQFP (PT) 10x10 mm
Timers: Multiple 8/16-bit timers
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: PDIP-40 (DIP-40, 0.600 in / 15.24 mm)
RoHS Status: Compliant
Program Memory (Flash): 8 KB (4K x 16 words)
Microchip Technology
Package: 40-pin PDIP (0.600 in / 15.24 mm)
Timers: 4 (Timer0/1/2/3)
Operating Temperature: -40 C to +85 C (Industrial, I suffix)
Microchip Technology
Timers: 1 x 8-bit, 3 x 16-bit
Operating Temperature: -40C to +85C (Industrial, -I suffix)
RoHS Status: Compliant (lead-free matte-tin)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4220-I/P

✅ Drop-In
Microchip Technology
📦 40-PDIP
PIC · 8-Bit · PIC18 · 40 MHz · 10 MIPS · 100 ns · Flash · 4 KB (2K x 16)

✓ In Stock

$4.78 / Unit

View Datasheet →

PIC18F4221-I/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 40-PDIP
PIC18 (8-bit RISC) · 4 KB (2K x 16) · 512 bytes · 256 bytes · 40 MHz · 16 MIPS (200 ns instruction cycle) · 4.2 V to 5.5 V · 36

✓ In Stock

$3.15 / Unit

View Datasheet →

PIC18F4320-I/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 40-PDIP
PIC18 (8-bit RISC, Harvard) · 77 single-word instructions · 40 MHz (10 MIPS) · 8 KB (4K x 16) · 512 bytes · 256 bytes · 2.0 V to 5.5 V · 36

✓ In Stock

$4.05 / Unit

View Datasheet →

PIC18F4520-I/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 40-PDIP
8-bit PIC18 enhanced RISC · 40 MHz (10 MIPS) · 32 KB (16K x 16) · 1.5 KB (1536 bytes) · 256 bytes · 4.2 V to 5.5 V · 36 · 10-bit, up to 13 channels

✓ In Stock

$5.35 / Unit

View Datasheet →

PIC18F4620-I/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 40-PDIP
PIC 18F · PIC · 8-bit · Flash · 64 KB (32K x 16) · 3968 bytes · 1024 bytes · 40 MHz (10 MIPS)

✓ In Stock

$5.08 / Unit

View Datasheet →

PIC18F458-E/P

✅ Drop-In
📦 40-PDIP
Same 40-PDIP, 32KB Flash vs 4KB (8x), 1536B RAM vs 512B, adds CAN module

📋 Reference alternative (not in catalog)

PIC18F4220-E/P Maximum Ratings & Electrical Characteristics

Core PIC18 8-bit RISC
Program Memory (Flash) 4 KB (2K x 16)
RAM 512 bytes
EEPROM 256 bytes
Maximum CPU Speed 25 MHz (10 MIPS)
Operating Voltage 4.2 V to 5.5 V
Number of I/O Pins 36
ADC 10-bit, 13 channels
Comparators 2 analog comparators
CCP/PWM Modules 2 CCP modules (10-bit PWM)
Timers 2 x 8-bit + 1 x 16-bit
Serial Interfaces 1 x SPI/I2C (MSSP), 1 x USART (AUSART)
Oscillator Internal + external (selectable)
Package 40-pin PDIP (P)
Operating Temperature -40C to +125C (Extended, 'E' suffix)
Instruction Set 77 single-word instructions
Self-Programming Yes
In-Circuit Debug MPLAB ICD
Mounting Type Through-Hole (PDIP)
MSL Level 1 (per tube, not moisture-sensitive)
RoHS Status Compliant (lead-free)

PIC18F4220-E/P Pin Configuration

DIP-40 Package Pinout Diagram DIP-40 40-pin dual inline, 7.62mm pitch, JEDEC MS-001. 1 40 2 39 3 38 4 37 5 36 6 35 7 34 8 33 9 32 10 31 11 30 12 29 13 28 14 27 15 26 16 25 17 24 18 23 19 22 20 21 DIP-40
Pin 1 MCLR/VPP — Reset input / programming voltage
Pin 2 RA0/AN0 — PORTA bit 0 / ADC channel 0
Pin 3 RA1/AN1 — PORTA bit 1 / ADC channel 1
Pin 4 RA2/AN2/VREF- — PORTA bit 2 / ADC channel 2 / VREF-
Pin 5 RA3/AN3/VREF+ — PORTA bit 3 / ADC channel 3 / VREF+
Pin 6 RA4/T0CKI/C1OUT — PORTA bit 4 / Timer0 clock input / Comparator1 output
Pin 7 RA5/AN4/SS/C2OUT — PORTA bit 5 / ADC channel 4 / SPI slave select / Comparator2 output
Pin 8 RE0/RD/AN5 — PORTE bit 0 / Parallel Slave Port read / ADC channel 5
Pin 9 RE1/WR/AN6 — PORTE bit 1 / Parallel Slave Port write / ADC channel 6
Pin 10 RE2/CS/AN7 — PORTE bit 2 / Parallel Slave Port CS / ADC channel 7
Pin 11 VDD — Positive supply (4.2V to 5.5V)
Pin 12 VSS — Ground
Pin 13 OSC1/CLKI/RA7 — Oscillator crystal input / external clock / PORTA bit 7
Pin 14 OSC2/CLKO/RA6 — Oscillator crystal output / clock out / PORTA bit 6
Pin 15 RC0/T1OSO/T1CKI — PORTC bit 0 / Timer1 oscillator out / Timer1 clock in
Pin 16 RC1/T1OSI/CCP2 — PORTC bit 1 / Timer1 oscillator in / CCP2
Pin 17 RC2/CCP1 — PORTC bit 2 / CCP1
Pin 18 RC3/SCK/SCL — PORTC bit 3 / SPI clock / I2C clock
Pin 19 RC4/SDI/SDA — PORTC bit 4 / SPI data in / I2C data
Pin 20 RC5/SDO — PORTC bit 5 / SPI data out
Pin 21 RC6/TX/CK — PORTC bit 6 / USART transmit / USART clock
Pin 22 RC7/RX/DT — PORTC bit 7 / USART receive / USART data
Pin 23 RB0/INT0 — PORTB bit 0 / External interrupt 0
Pin 24 RB1/INT1 — PORTB bit 1 / External interrupt 1
Pin 25 RB2/INT2 — PORTB bit 2 / External interrupt 2
Pin 26 RB3/CCP2 — PORTB bit 3 / CCP2 alternate
Pin 27 RB4 — PORTB bit 4
Pin 28 RB5 — PORTB bit 5
Pin 29 RB6/PGC — PORTB bit 6 / ICSP clock
Pin 30 RB7/PGD — PORTB bit 7 / ICSP data
Pin 31 VDD — Positive supply (4.2V to 5.5V)
Pin 32 VSS — Ground
Pin 33 RD0/PSP0 — PORTD bit 0 / Parallel Slave Port bit 0
Pin 34 RD1/PSP1 — PORTD bit 1 / Parallel Slave Port bit 1
Pin 35 RD2/PSP2 — PORTD bit 2 / Parallel Slave Port bit 2
Pin 36 RD3/PSP3 — PORTD bit 3 / Parallel Slave Port bit 3
Pin 37 RD4/PSP4 — PORTD bit 4 / Parallel Slave Port bit 4
Pin 38 RD5/PSP5 — PORTD bit 5 / Parallel Slave Port bit 5
Pin 39 RD6/PSP6 — PORTD bit 6 / Parallel Slave Port bit 6
Pin 40 RD7/PSP7 — PORTD bit 7 / Parallel Slave Port bit 7

Typical Applications

PIC18F4220-E/P is suitable for 6 applications: Industrial Control Logic, Sensor Interface and Data Acquisition, Appliance and White Goods Controllers, Automotive Body Electronics (Non-Safety), Educational and Prototyping Platforms, Low-Cost HMI and Display Modules.

🏭

Industrial Control Logic

The PIC18F4220-E/P's 4 KB Flash, 512B RAM, and 36 I/O pins make it well-suited to industrial control logic such as machine sequence controllers, relay drivers, and discrete I/O expansion modules. Its 25 MHz / 10 MIPS throughput executes deterministic state machines and PID loops within the millisecond timeframe, while the -40C to +125C extended temperature grade supports deployment near motors, heaters, and outdoor cabinets without additional thermal qualification. The 13-channel 10-bit ADC reads analog sensor signals (temperature, pressure, flow) directly, eliminating external ADC ICs. Recommended companion parts: PIC18F4220-I/P (pin-compatible industrial variant), PIC18F26K80-I/SP (USB/CAN upgrade path), MCP2551 (CAN transceiver).

🌐

Sensor Interface and Data Acquisition

The PIC18F4220-E/P's 13-channel 10-bit ADC, two analog comparators, and 36 I/O lines support multi-sensor data acquisition in HVAC, agriculture, and environmental telemetry. The MSSP peripheral communicates SPI or I2C sensors at scale (e.g. temperature, humidity, accelerometers) and the I2C microcontroller supports both master and 3-pin SPI peripherals at 5V levels. Its self-programming Flash supports firmware upgrades for field-deployed sensor nodes, while the extended -40C to +125C temperature grade tolerates outdoor and rooftop installations. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant), MCP9808 (digital temperature sensor), 24LC256 (I2C EEPROM for data logging).

🏭

Appliance and White Goods Controllers

White goods such as washing machines, dishwashers, and ovens require reliable 5V microcontroller control with abundant digital I/O for keypads, displays, and motor drivers - the exact profile of the PIC18F4220-E/P. Its 36 I/O lines drive 7-segment displays, LED indicators, and triac interfaces directly, while the two CCP/PWM modules generate motor-control and triac-firing signals at the required timing resolution. The 2 analog comparators detect zero-crossing of the AC line and over-current events. The extended -40C to +125C operating range survives the elevated ambient temperatures behind appliance control panels. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant), MCP23S17 (I/O expander), ULN2003 (relay/display driver array).

🚗

Automotive Body Electronics (Non-Safety)

Automotive body modules - interior lighting, seat controllers, mirror actuators, and HVAC blend doors - need an extended-temperature 5V MCU with moderate Flash and I/O. The PIC18F4220-E/P's -40C to +125C grade and 36 I/O satisfy those needs; designers building production-volume automotive designs should pair the standard part with the AEC-Q100-qualified PIC18F4220-E/P automotive equivalent if available. The CAN module is not present, so this MCU suits LIN or simple discrete/analog body-electronics tasks rather than CAN-connected modules. Recommended companion parts: MCP2551 (CAN, if upgrading to PIC18F458 family), TJA1027 (LIN transceiver), MCP1700 (5V LDO).

🔧

Educational and Prototyping Platforms

The PIC18F4220-E/P is widely used in university embedded-systems courses and hobbyist prototyping because the 40-PDIP package drops into standard 0.6-inch DIP sockets and breadboards - no surface-mount rework required. The MPLAB X IDE + XC8 C compiler + MPLAB ICD in-circuit debugger toolchain is fully supported, and 77 single-word instructions make assembly-language teaching straightforward. Self-programming Flash allows students to experiment with bootloader designs and in-field firmware updates. The moderate 4 KB Flash fits core peripheral-driver exercises while still leaving headroom for multi-file C projects. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant for coursework), PICkit 3 (programmer/debugger), MCP23S17 (I/O expander for lab exercises).

📺

Low-Cost HMI and Display Modules

The PIC18F4220-E/P's 36 I/O pins and SPI/I2C peripherals enable cost-optimized Human-Machine Interface (HMI) modules with character LCDs, 7-segment LED displays, and small graphical OLEDs. The two CCP/PWM channels drive LED brightness and backlight dimming via PWM, while the MSSP talks to SPI LCDs or I2C keypads. The 13-channel 10-bit ADC reads potentiometer inputs and analog sensor feedback for menu navigation. The 4 KB Flash holds state-machine code, debounce logic, and small custom character sets. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant), HD44780-compatible LCD, MCP23S17 (keypad/display expander).

Recommended Products Summary

PIC18F26K80-I/SP Microchip Technology Used in: Industrial Control Logic MCP2551 CAN transceiver for industrial networks Used in: Industrial Control Logic MCP1700 3.3V LDO for analog rail Used in: Industrial Control Logic, Sensor Interface and Data Acquisition, Automotive Body Electronics (Non-Safety) MCP9808 High-accuracy digital temperature sensor Used in: Sensor Interface and Data Acquisition 24LC256 I2C EEPROM for sensor data logging Used in: Sensor Interface and Data Acquisition MCP23S17 16-bit SPI I/O expander Used in: Appliance and White Goods Controllers, Educational and Prototyping Platforms, Low-Cost HMI and Display Modules ULN2003 Darlington array for relay driving Used in: Appliance and White Goods Controllers TJA1027 LIN transceiver for body electronics Used in: Automotive Body Electronics (Non-Safety) PIC18F4220-I/P Microchip Technology Used in: Educational and Prototyping Platforms HD44780 Character LCD controller Used in: Low-Cost HMI and Display Modules
What is the program memory size of the PIC18F4220-E/P?
The PIC18F4220-E/P integrates 4 KB of self-programmable Flash program memory, organized as 2K x 16 words. According to the Microchip PIC18F2220/2320/4220/4320 datasheet (DS39599G), the Flash memory supports ICSP (In-Circuit Serial Programming) and self-programming under firmware control, enabling field updates without an external programmer.
How much RAM and EEPROM does the PIC18F4220-E/P have?
The PIC18F4220-E/P provides 512 bytes of SRAM data memory and 256 bytes of non-volatile EEPROM data memory. The SRAM serves the 8-bit working registers and user variables, while the EEPROM supports retention of calibration data, configuration parameters, and counters across power cycles without external storage chips.
What is the operating voltage range of the PIC18F4220-E/P?
The PIC18F4220-E/P operates from 4.2 V to 5.5 V across its full Extended temperature range of -40C to +125C. This 5V rail is typical for PIC18F family parts; designers needing sub-3V operation should consider the PIC18LF-series variants, which add an extra low-voltage operating mode below 4.2 V.
How many ADC channels and timers does the PIC18F4220-E/P have?
The PIC18F4220-E/P includes a 10-bit Analog-to-Digital Converter with 13 input channels, plus two 8-bit timers (Timer0, Timer2) and one 16-bit timer (Timer1). The 10-bit ADC supports both single-ended and differential conversion modes, while the three timers enable PWM generation, event capture, and real-time interrupt-driven scheduling.
What is the maximum CPU clock speed of the PIC18F4220-E/P?
The PIC18F4220-E/P runs at up to 25 MHz crystal input, delivering 10 MIPS (Million Instructions Per Second) of throughput. Each instruction executes in 4 oscillator cycles (100 ns at 40 MHz FOSC/4 internal), which is the foundation of the 10 MIPS figure cited in Microchip datasheet DS39599G.
Where can I buy PIC18F4220-E/P online and what is the price?
The PIC18F4220-E/P is in stock at DigiKey, Mouser, LCSC, and Bonchip as of 2026-09-27. Pricing on a 1-piece tier is approximately 7.56 USD from authorized distributors; bulk pricing drops below 5.00 USD at 1000-piece quantities. LCSC lists the part from 2.68 USD, reflecting regional wholesale pricing rather than the authorized North American distributor channel.
Is PIC18F4220-E/P in stock and what is the lead time?
As of 2026-09-27, PIC18F4220-E/P is actively stocked at multiple authorized distributors including DigiKey, Mouser, and Bonchip, with immediate shipment available for small quantities. Wolfchip also reports 45,410 pieces in stock. Bulk orders above 5000 pieces typically carry a 4-6 week lead time through the manufacturer channel.
What is the difference between PIC18F4220 and PIC18F4220-I/P?
The PIC18F4220-E/P carries the Extended temperature grade (-40C to +125C), while the PIC18F4220-I/P is the Industrial grade (-40C to +85C). Both share the identical 4 KB Flash, 512B RAM, 256B EEPROM, 25 MHz/10 MIPS core, and 40-PDIP pinout, so they are drop-in compatible - select 'E' for harsh environments and 'I' for typical commercial/industrial designs.
Which Microchip PIC18 is the best drop-in replacement for PIC18F4220-E/P?
The PIC18F4220-I/P is the closest Microchip drop-in alternative - same 40-PDIP package, same 4 KB Flash, 512B RAM, 256B EEPROM, and same 36 I/O pinout - differing only in the -40C to +85C industrial temperature grade versus the -40C to +125C extended grade of the 'E/P' suffix. It is a true pin-to-pin replacement when extended-temperature qualification is not required.
PIC18F4220-E/P vs PIC18F458-E/P - which is better for industrial control?
The PIC18F4220-E/P provides 4 KB Flash / 512B RAM, while the PIC18F458-E/P upgrades to 32 KB Flash / 1536B RAM and adds a CAN module. For industrial control tasks needing more program memory or CAN bus, choose PIC18F458-E/P; for compact sensor or low-cost logic control, PIC18F4220-E/P is the better choice.
When should I choose PIC18F4220-E/P over PIC18F26K22-I/SP?
Choose the PIC18F4220-E/P when you need an extended-temperature 40-PDIP through-hole part for breadboarding or legacy industrial backplanes; the PIC18F26K22-I/SP delivers much larger 64 KB Flash / 4 KB RAM and runs at 64 MHz / 16 MIPS, but ships only in surface-mount packages and at the Industrial temperature grade. Pick PIC18F4220-E/P for drop-in 5V 40-pin DIP sockets.
Where can I download the PIC18F4220-E/P datasheet PDF?
The Microchip datasheet for PIC18F4220-E/P is published as document DS39599G and is available as a free PDF download from Microchip's product page at microchip.com/en-us/product/PIC18F4220. The PDF covers electrical characteristics, peripheral descriptions, instruction set, and programming specifications. Aggregator sites such as datasheets.com also host mirror copies.
Where can I find the PIC18F4220-E/P pinout diagram?
The PIC18F4220-E/P pinout is published in the Microchip datasheet DS39599G section 'Pin Diagrams' and reproduced on the XAIPART product page. Pin 1 is located at the top-left of the PDIP package (notch up). Key pins include MCLR/VPP (pin 1), OSC1/OSC2 (pins 13/14), VDD/VSS pairs, and 36 I/O lines on PORTA-PORTE.
Is PIC18F4220-E/P RoHS compliant?
Yes, the PIC18F4220-E/P is RoHS compliant and lead-free per the Microchip product page and DigiKey regulatory data as of 2026-09-27. The PDIP-40 package with matte tin lead finish is fully compatible with lead-free soldering profiles up to 260C peak reflow, despite being a through-hole part, allowing modern SMT-compatible assembly processes.
What is the best {alternative_brand} equivalent for PIC18F4220-E/P?
Within Microchip Technology (same brand), the PIC18F4220-I/P is the closest drop-in equivalent - identical 40-PDIP package and 36 I/O pinout, differing only in the -40C to +85C industrial temperature grade. Cross-brand 8-bit MCU drop-ins in 40-PDIP are extremely rare because PIC18 has a proprietary Harvard RISC core; the most common migration paths are to Atmel/Microchip ATmega or NXP MC9S08 families, which require software porting.

Engineering reference data for PIC18F4220-E/P — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18F4220-E/P when you need a 5V, 40-PDIP through-hole 8-bit Flash MCU with 4 KB program memory, 36 I/O, and -40C to +125C extended temperature grade - the typical fit for industrial control, sensor interfaces, and educational prototyping. Choose the pin-compatible PIC18F4220-I/P if your design only needs -40C to +85C industrial temperature (lower cost). Choose PIC18F4221-I/P, PIC18F4320-I/P, PIC18F4520-I/P, or PIC18F4620-I/P if you need 16-64 KB Flash for larger code bases while keeping the same 40-PDIP footprint. Choose PIC18F458-E/P when you need CAN bus connectivity (automotive/industrial networking). All these parts share the same 40-PDIP pinout, allowing PCB reuse with only firmware retargeting.

Comparison with Alternatives

Parameter This Product PIC18F4220-I/P PIC18F4221-I/P PIC18F4320-I/P PIC18F458-E/P
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 40-PDIP 40-PDIP 40-PDIP 40-PDIP 40-PDIP
Flash Memory 4 KB (2K x 16) 4 KB 16 KB 8 KB 32 KB
RAM 512 bytes 512 bytes 768 bytes 512 bytes 1536 bytes
EEPROM 256 bytes 256 bytes 256 bytes 256 bytes 256 bytes
Max CPU Speed 25 MHz / 10 MIPS 25 MHz / 10 MIPS 40 MHz / 10 MIPS 40 MHz / 10 MIPS 40 MHz / 10 MIPS
I/O Pins 36 36 36 36 36
ADC 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 8 channels
Operating Temperature -40C to +125C (Extended) -40C to +85C (Industrial) -40C to +85C (Industrial) -40C to +85C (Industrial) -40C to +125C (Extended)
Special Peripherals 2 CCP, 2 comparators, MSSP, AUSART Same Adds 1 ECCP Adds 1 ECCP Adds CAN module

Key Differentiators

  • Extended industrial temperature grade vs typical industrial-grade alternatives (vs PIC18F4220-I/P)
  • Upward code compatibility across the entire PIC18 family (vs PIC18F458-E/P)
  • Through-hole 40-PDIP package ideal for prototyping and legacy systems (vs PIC18F26K22-I/SP)

Design Notes

The PIC18F4220-E/P operates from 4.2 V to 5.5 V; place a 100 nF decoupling capacitor on each VDD/VSS pair (pins 11/12 and 31/32) as close to the package as possible, and add a bulk 10 uF tantalum or ceramic cap on the main 5 V rail. For battery-backed designs, the MCP1700 3.3 V/5 V LDO pair supplies low-quiescent standby current and reduces sleep-mode drain below 1 uA.

When laying out the PCB, keep the ICSP pins (RB6/PGC = pin 29, RB7/PGD = pin 30) accessible for programming/debug, even in production boards - this enables field firmware updates without desoldering. The MCLR pin (pin 1) must have a 10 kohm pull-up to VDD for normal operation; in noisy industrial environments add a 100 nF cap from MCLR to VSS to reject fast transient resets.

For SPI or I2C buses, keep traces under 50 mm with a ground reference on an adjacent layer. Add 4.7 kohm pull-ups on I2C lines (RC3/SCL, RC4/SDA) and series 100 ohm resistors on SPI clock lines (RC3/SCK) when running above 5 MHz to damp reflections. Configure the MSSP peripheral for open-drain I2C mode rather than push-pull to avoid bus contention with other nodes.

Configuration bits (CONFIG1H through CONFIG5H) must be programmed correctly to enable the internal oscillator or external crystal; leaving the oscillator configuration bits in the default state is a common source of 'dead' boards. The ADC requires a minimum acquisition time (Tacq) of about 20 us at 5 V - skip this delay and channel readings will be non-linear. The 'E' suffix is for Extended grade - if your design only needs -40C to +85C, use the cheaper 'I' suffix variant.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant and lead-free per Microchip product page and DigiKey regulatory data as of 2026-09-27. Standard PIC18F4220-E/P is not AEC-Q100 qualified - production automotive designs should use the PIC18F4220-E/P automotive equivalent or PIC18F45K80 family.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

Related Searches

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Related Components & Terms

Microchip Technology PIC18F4220 PIC18F4220-E/P PIC18F4220-I/P PIC18F4221-I/P PIC18F4320-I/P PIC18F458-E/P microcontroller MCU 8-bit microcontroller PIC18 family RISC architecture Flash memory EEPROM 10-bit ADC CCP/PWM MSSP MPLAB X IDE XC8 compiler 40-PDIP PDIP package ICSP RoHS industrial temperature grade
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