PIC18F4220-E/P - 8-Bit 25MHz 4KB Flash MCU 40-PDIP | Microchip
MPN: PIC18F4220-E/P ✓ Active| Qty | Unit Price | Extended |
|---|---|---|
| 1 | $7.56 | $7.56 |
| 10 | $6.84 | $68.40 |
| 100 | $6.05 | $605.00 |
| 500 | $5.27 | $2,635.00 |
| 1,000 | $4.65 | $4,650.00 |
PIC18F4220-E/P Overview
A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program memory, RAM, and configurable peripherals into one package. The PIC18 family belongs to Microchip's 8-bit RISC microcontroller hierarchy - an 8-bit MCU -> PIC microcontroller -> PIC18 family -> Flash-based microcontroller -> embedded controller. Within this hierarchy the PIC18F4220 sits in the mid-range tier, balancing program memory, peripheral count, and I/O count for embedded control tasks. The 'E' suffix indicates the Extended industrial temperature grade of -40C to +125C, while the 'P' suffix designates the PDIP-40 package.
Key features of this part include 36 digital I/O pins, 13 channels of 10-bit Analog-to-Digital converter (ADC), 2 analog comparators, 2 Capture/Compare/PWM (CCP) modules, a 10-bit enhanced PWM, a synchronous serial port configurable as SPI or I2C, two 8-bit timers plus one 16-bit timer, a parallel slave port, and an internal oscillator. The instruction set offers only 77 single-word instructions and is upward compatible with PIC16C5X, PIC12CXXX, PIC16CXX and PIC17CXX devices, easing software migration from older Microchip parts.
Typical applications include industrial control, sensor interface, low-power remote controls, appliance controllers, and small embedded data-acquisition nodes. The 10 MIPS performance, broad peripheral mix, and self-programming support make it a strong fit for legacy PIC18 designs and for new designs targeting the PIC18 ecosystem with MPLAB X and XC8 toolchain compatibility.
When designing with this device, place decoupling capacitors as close as possible to the VDD/VSS pins and follow Microchip's MPLAB ICD in-circuit debugging guidelines. The Extended temperature grade (-40C to +125C) allows deployment in automotive, industrial, and outdoor environments without additional qualification.
This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found on any single manufacturer or distributor page.
Drop-in alternatives for PIC18F4220-E/P — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.
Variants in this series
Same-series models that are drop-in compatible with PIC18F4220-E/P (same form factor and footprint) — differing in Package, Timers, Operating Temperature, RoHS Status, Program Memory (Flash).
Quick Comparison Tool — Select alternative parts for side-by-side comparison:
PIC18F4220-I/P
✅ Drop-In✓ In Stock
$4.78 / Unit
View Datasheet →PIC18F4221-I/P
✅ Drop-In ⚠️ Specs Unverified✓ In Stock
$3.15 / Unit
View Datasheet →PIC18F4320-I/P
✅ Drop-In ⚠️ Specs Unverified✓ In Stock
$4.05 / Unit
View Datasheet →PIC18F4520-I/P
✅ Drop-In ⚠️ Specs Unverified✓ In Stock
$5.35 / Unit
View Datasheet →PIC18F4620-I/P
✅ Drop-In ⚠️ Specs Unverified✓ In Stock
$5.08 / Unit
View Datasheet →PIC18F458-E/P
✅ Drop-In📋 Reference alternative (not in catalog)
PIC18F4220-E/P Maximum Ratings & Electrical Characteristics
| Core | PIC18 8-bit RISC |
| Program Memory (Flash) | 4 KB (2K x 16) |
| RAM | 512 bytes |
| EEPROM | 256 bytes |
| Maximum CPU Speed | 25 MHz (10 MIPS) |
| Operating Voltage | 4.2 V to 5.5 V |
| Number of I/O Pins | 36 |
| ADC | 10-bit, 13 channels |
| Comparators | 2 analog comparators |
| CCP/PWM Modules | 2 CCP modules (10-bit PWM) |
| Timers | 2 x 8-bit + 1 x 16-bit |
| Serial Interfaces | 1 x SPI/I2C (MSSP), 1 x USART (AUSART) |
| Oscillator | Internal + external (selectable) |
| Package | 40-pin PDIP (P) |
| Operating Temperature | -40C to +125C (Extended, 'E' suffix) |
| Instruction Set | 77 single-word instructions |
| Self-Programming | Yes |
| In-Circuit Debug | MPLAB ICD |
| Mounting Type | Through-Hole (PDIP) |
| MSL Level | 1 (per tube, not moisture-sensitive) |
| RoHS Status | Compliant (lead-free) |
PIC18F4220-E/P Pin Configuration
| Pin 1 | MCLR/VPP — Reset input / programming voltage |
| Pin 2 | RA0/AN0 — PORTA bit 0 / ADC channel 0 |
| Pin 3 | RA1/AN1 — PORTA bit 1 / ADC channel 1 |
| Pin 4 | RA2/AN2/VREF- — PORTA bit 2 / ADC channel 2 / VREF- |
| Pin 5 | RA3/AN3/VREF+ — PORTA bit 3 / ADC channel 3 / VREF+ |
| Pin 6 | RA4/T0CKI/C1OUT — PORTA bit 4 / Timer0 clock input / Comparator1 output |
| Pin 7 | RA5/AN4/SS/C2OUT — PORTA bit 5 / ADC channel 4 / SPI slave select / Comparator2 output |
| Pin 8 | RE0/RD/AN5 — PORTE bit 0 / Parallel Slave Port read / ADC channel 5 |
| Pin 9 | RE1/WR/AN6 — PORTE bit 1 / Parallel Slave Port write / ADC channel 6 |
| Pin 10 | RE2/CS/AN7 — PORTE bit 2 / Parallel Slave Port CS / ADC channel 7 |
| Pin 11 | VDD — Positive supply (4.2V to 5.5V) |
| Pin 12 | VSS — Ground |
| Pin 13 | OSC1/CLKI/RA7 — Oscillator crystal input / external clock / PORTA bit 7 |
| Pin 14 | OSC2/CLKO/RA6 — Oscillator crystal output / clock out / PORTA bit 6 |
| Pin 15 | RC0/T1OSO/T1CKI — PORTC bit 0 / Timer1 oscillator out / Timer1 clock in |
| Pin 16 | RC1/T1OSI/CCP2 — PORTC bit 1 / Timer1 oscillator in / CCP2 |
| Pin 17 | RC2/CCP1 — PORTC bit 2 / CCP1 |
| Pin 18 | RC3/SCK/SCL — PORTC bit 3 / SPI clock / I2C clock |
| Pin 19 | RC4/SDI/SDA — PORTC bit 4 / SPI data in / I2C data |
| Pin 20 | RC5/SDO — PORTC bit 5 / SPI data out |
| Pin 21 | RC6/TX/CK — PORTC bit 6 / USART transmit / USART clock |
| Pin 22 | RC7/RX/DT — PORTC bit 7 / USART receive / USART data |
| Pin 23 | RB0/INT0 — PORTB bit 0 / External interrupt 0 |
| Pin 24 | RB1/INT1 — PORTB bit 1 / External interrupt 1 |
| Pin 25 | RB2/INT2 — PORTB bit 2 / External interrupt 2 |
| Pin 26 | RB3/CCP2 — PORTB bit 3 / CCP2 alternate |
| Pin 27 | RB4 — PORTB bit 4 |
| Pin 28 | RB5 — PORTB bit 5 |
| Pin 29 | RB6/PGC — PORTB bit 6 / ICSP clock |
| Pin 30 | RB7/PGD — PORTB bit 7 / ICSP data |
| Pin 31 | VDD — Positive supply (4.2V to 5.5V) |
| Pin 32 | VSS — Ground |
| Pin 33 | RD0/PSP0 — PORTD bit 0 / Parallel Slave Port bit 0 |
| Pin 34 | RD1/PSP1 — PORTD bit 1 / Parallel Slave Port bit 1 |
| Pin 35 | RD2/PSP2 — PORTD bit 2 / Parallel Slave Port bit 2 |
| Pin 36 | RD3/PSP3 — PORTD bit 3 / Parallel Slave Port bit 3 |
| Pin 37 | RD4/PSP4 — PORTD bit 4 / Parallel Slave Port bit 4 |
| Pin 38 | RD5/PSP5 — PORTD bit 5 / Parallel Slave Port bit 5 |
| Pin 39 | RD6/PSP6 — PORTD bit 6 / Parallel Slave Port bit 6 |
| Pin 40 | RD7/PSP7 — PORTD bit 7 / Parallel Slave Port bit 7 |
Typical Applications
PIC18F4220-E/P is suitable for 6 applications: Industrial Control Logic, Sensor Interface and Data Acquisition, Appliance and White Goods Controllers, Automotive Body Electronics (Non-Safety), Educational and Prototyping Platforms, Low-Cost HMI and Display Modules.
Industrial Control Logic
The PIC18F4220-E/P's 4 KB Flash, 512B RAM, and 36 I/O pins make it well-suited to industrial control logic such as machine sequence controllers, relay drivers, and discrete I/O expansion modules. Its 25 MHz / 10 MIPS throughput executes deterministic state machines and PID loops within the millisecond timeframe, while the -40C to +125C extended temperature grade supports deployment near motors, heaters, and outdoor cabinets without additional thermal qualification. The 13-channel 10-bit ADC reads analog sensor signals (temperature, pressure, flow) directly, eliminating external ADC ICs. Recommended companion parts: PIC18F4220-I/P (pin-compatible industrial variant), PIC18F26K80-I/SP (USB/CAN upgrade path), MCP2551 (CAN transceiver).
Recommended
Sensor Interface and Data Acquisition
The PIC18F4220-E/P's 13-channel 10-bit ADC, two analog comparators, and 36 I/O lines support multi-sensor data acquisition in HVAC, agriculture, and environmental telemetry. The MSSP peripheral communicates SPI or I2C sensors at scale (e.g. temperature, humidity, accelerometers) and the I2C microcontroller supports both master and 3-pin SPI peripherals at 5V levels. Its self-programming Flash supports firmware upgrades for field-deployed sensor nodes, while the extended -40C to +125C temperature grade tolerates outdoor and rooftop installations. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant), MCP9808 (digital temperature sensor), 24LC256 (I2C EEPROM for data logging).
Recommended
Appliance and White Goods Controllers
White goods such as washing machines, dishwashers, and ovens require reliable 5V microcontroller control with abundant digital I/O for keypads, displays, and motor drivers - the exact profile of the PIC18F4220-E/P. Its 36 I/O lines drive 7-segment displays, LED indicators, and triac interfaces directly, while the two CCP/PWM modules generate motor-control and triac-firing signals at the required timing resolution. The 2 analog comparators detect zero-crossing of the AC line and over-current events. The extended -40C to +125C operating range survives the elevated ambient temperatures behind appliance control panels. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant), MCP23S17 (I/O expander), ULN2003 (relay/display driver array).
Recommended
Automotive Body Electronics (Non-Safety)
Automotive body modules - interior lighting, seat controllers, mirror actuators, and HVAC blend doors - need an extended-temperature 5V MCU with moderate Flash and I/O. The PIC18F4220-E/P's -40C to +125C grade and 36 I/O satisfy those needs; designers building production-volume automotive designs should pair the standard part with the AEC-Q100-qualified PIC18F4220-E/P automotive equivalent if available. The CAN module is not present, so this MCU suits LIN or simple discrete/analog body-electronics tasks rather than CAN-connected modules. Recommended companion parts: MCP2551 (CAN, if upgrading to PIC18F458 family), TJA1027 (LIN transceiver), MCP1700 (5V LDO).
Recommended
Educational and Prototyping Platforms
The PIC18F4220-E/P is widely used in university embedded-systems courses and hobbyist prototyping because the 40-PDIP package drops into standard 0.6-inch DIP sockets and breadboards - no surface-mount rework required. The MPLAB X IDE + XC8 C compiler + MPLAB ICD in-circuit debugger toolchain is fully supported, and 77 single-word instructions make assembly-language teaching straightforward. Self-programming Flash allows students to experiment with bootloader designs and in-field firmware updates. The moderate 4 KB Flash fits core peripheral-driver exercises while still leaving headroom for multi-file C projects. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant for coursework), PICkit 3 (programmer/debugger), MCP23S17 (I/O expander for lab exercises).
Recommended
Low-Cost HMI and Display Modules
The PIC18F4220-E/P's 36 I/O pins and SPI/I2C peripherals enable cost-optimized Human-Machine Interface (HMI) modules with character LCDs, 7-segment LED displays, and small graphical OLEDs. The two CCP/PWM channels drive LED brightness and backlight dimming via PWM, while the MSSP talks to SPI LCDs or I2C keypads. The 13-channel 10-bit ADC reads potentiometer inputs and analog sensor feedback for menu navigation. The 4 KB Flash holds state-machine code, debounce logic, and small custom character sets. Recommended companion parts: PIC18F4220-I/P (industrial-grade variant), HD44780-compatible LCD, MCP23S17 (keypad/display expander).
Recommended
Recommended Products Summary
Engineering reference data for PIC18F4220-E/P — comparison, design guidance, and compliance information.
Selection Guide
Comparison with Alternatives
| Parameter | This Product | PIC18F4220-I/P | PIC18F4221-I/P | PIC18F4320-I/P | PIC18F458-E/P |
|---|---|---|---|---|---|
| Brand | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology |
| Package | 40-PDIP | 40-PDIP | 40-PDIP | 40-PDIP | 40-PDIP |
| Flash Memory | 4 KB (2K x 16) | 4 KB | 16 KB | 8 KB | 32 KB |
| RAM | 512 bytes | 512 bytes | 768 bytes | 512 bytes | 1536 bytes |
| EEPROM | 256 bytes | 256 bytes | 256 bytes | 256 bytes | 256 bytes |
| Max CPU Speed | 25 MHz / 10 MIPS | 25 MHz / 10 MIPS | 40 MHz / 10 MIPS | 40 MHz / 10 MIPS | 40 MHz / 10 MIPS |
| I/O Pins | 36 | 36 | 36 | 36 | 36 |
| ADC | 10-bit, 13 channels | 10-bit, 13 channels | 10-bit, 13 channels | 10-bit, 13 channels | 10-bit, 8 channels |
| Operating Temperature | -40C to +125C (Extended) | -40C to +85C (Industrial) | -40C to +85C (Industrial) | -40C to +85C (Industrial) | -40C to +125C (Extended) |
| Special Peripherals | 2 CCP, 2 comparators, MSSP, AUSART | Same | Adds 1 ECCP | Adds 1 ECCP | Adds CAN module |
Key Differentiators
- Extended industrial temperature grade vs typical industrial-grade alternatives (vs PIC18F4220-I/P)
- Upward code compatibility across the entire PIC18 family (vs PIC18F458-E/P)
- Through-hole 40-PDIP package ideal for prototyping and legacy systems (vs PIC18F26K22-I/SP)
Design Notes
The PIC18F4220-E/P operates from 4.2 V to 5.5 V; place a 100 nF decoupling capacitor on each VDD/VSS pair (pins 11/12 and 31/32) as close to the package as possible, and add a bulk 10 uF tantalum or ceramic cap on the main 5 V rail. For battery-backed designs, the MCP1700 3.3 V/5 V LDO pair supplies low-quiescent standby current and reduces sleep-mode drain below 1 uA.
When laying out the PCB, keep the ICSP pins (RB6/PGC = pin 29, RB7/PGD = pin 30) accessible for programming/debug, even in production boards - this enables field firmware updates without desoldering. The MCLR pin (pin 1) must have a 10 kohm pull-up to VDD for normal operation; in noisy industrial environments add a 100 nF cap from MCLR to VSS to reject fast transient resets.
For SPI or I2C buses, keep traces under 50 mm with a ground reference on an adjacent layer. Add 4.7 kohm pull-ups on I2C lines (RC3/SCL, RC4/SDA) and series 100 ohm resistors on SPI clock lines (RC3/SCK) when running above 5 MHz to damp reflections. Configure the MSSP peripheral for open-drain I2C mode rather than push-pull to avoid bus contention with other nodes.
Configuration bits (CONFIG1H through CONFIG5H) must be programmed correctly to enable the internal oscillator or external crystal; leaving the oscillator configuration bits in the default state is a common source of 'dead' boards. The ADC requires a minimum acquisition time (Tacq) of about 20 us at 5 V - skip this delay and channel readings will be non-linear. The 'E' suffix is for Extended grade - if your design only needs -40C to +85C, use the cheaper 'I' suffix variant.
Compliance Information
RoHS compliant and lead-free per Microchip product page and DigiKey regulatory data as of 2026-09-27. Standard PIC18F4220-E/P is not AEC-Q100 qualified - production automotive designs should use the PIC18F4220-E/P automotive equivalent or PIC18F45K80 family.