Microchip Technology

PIC18F4221T-I/PT - 8-bit 40MHz 4KB Flash MCU | Microchip

MPN: PIC18F4221T-I/PT ✓ Active
In Stock Ships in 1-3 business days
4.2 V to 5.5 V Vdss 44-pin TQFP (PT) 10x10 mm Package 40 MHz (10 MIPS) Speed 4 KB (2K x 16) Memory
From $1.82 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $3.1 $3.10
10 $2.78 $27.80
100 $2.34 $234.00
500 $2.05 $1,025.00
1,000 $1.82 $1,820.00
ℹ️ All prices are in USD

PIC18F4221T-I/PT Overview

The Microchip Technology PIC18F4221T-I/PT is an 8-bit PIC18 microcontroller IC operating at up to 40 MHz with 4 KB (2K x 16) of Flash program memory, packaged in a 44-pin TQFP (10x10 mm) form factor. It is supplied in tape-and-reel packaging (suffix "T") and targets the industrial temperature range of -40C to +85C.

What is an 8-bit PIC microcontroller? An 8-bit MCU (microcontroller unit) is a small computer-on-a-chip that processes data 8 bits at a time. PIC microcontrollers from Microchip use a RISC (Reduced Instruction Set Computer) architecture with a Harvard memory structure, separating program and data buses for fast, deterministic execution. Within the broader semiconductor taxonomy, PIC18F belongs to the PIC18 family of enhanced Flash microcontrollers, itself part of the 8-bit MCU category, which sits under embedded controllers and integrated circuits. PIC18F parts are widely used for low-power, cost-sensitive applications requiring simple peripherals and easy migration across pin counts.

Key features of the PIC18F4221T-I/PT include 512 bytes of RAM, 256 bytes of EEPROM data memory, a 10-bit ADC with multiple channels, nanoWatt power-management technology for low-power sleep modes, and 36 digital I/O pins. The device supports supply voltages from 4.2V to 5.5V typical, includes an internal oscillator, multiple timers, USART, MSSP (I2C/SPI), and nanoWatt features for battery-friendly operation.

Architecturally, the PIC18F4221 uses an enhanced RISC core with 77 single-word instructions, hardware multiplier, and 16-bit wide instruction words. The 40 MHz clock delivers up to 10 MIPS (100 ns instruction execution), with interrupt handling, context saving, and a priority interrupt controller for deterministic real-time response. Peripheral integration is mature and well documented across Microchip's toolchain, including MPLAB X IDE, XC8 compilers, and a broad library of application notes.

Typical applications include industrial control, sensor interfaces, low-power remote controls, consumer appliances, automotive body and comfort modules, and USB-less embedded products where cost and power budget matter. The 36 I/O pins and 10-bit ADC also suit HMI (human-machine interface) front panels and instrument clusters.

When designing with this part, plan for a minimum 1uF decoupling capacitor on VDD and place it within 5 mm of the supply pin. For low-power designs, leverage nanoWatt modes (Idle, Sleep, and Timer1 oscillator) and verify the ADC acquisition time against source impedance.

This page synthesizes distributor pricing, drop-in same-package alternatives, and practical design notes not found in the manufacturer datasheet, giving engineers a faster path to a confident part selection.

Drop-in alternatives for PIC18F4221T-I/PT — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F4221T-I/PT (same form factor and footprint) — differing in Package, Timers, Core Architecture, Operating Temperature, ADC.

Microchip Technology
Package: 40-pin PDIP (P)
Timers: 2 x 8-bit + 1 x 16-bit
Operating Temperature: -40C to +125C (Extended, 'E' suffix)
Microchip Technology
Package: 40-PDIP (0.600", 15.24 mm)
Timers: 2 x 8-bit, 3 x 16-bit
Core Architecture: PIC18
Microchip Technology
Package: 44-pin QFN (ML)
Timers: 2 x 8-bit + 3 x 16-bit
Core Architecture: Enhanced Harvard RISC, 77 instructions
Microchip Technology
Package: 40-pin PDIP (DIP-40)
Timers: 1 x 8-bit, 3 x 16-bit
Operating Temperature: -40C to +85C (Industrial, -I suffix)
Microchip Technology
Package: 44-pin QFN (8x8 mm)
Timers: Multiple 8-bit and 16-bit timers
Core Architecture: PIC18 (8-bit, Harvard RISC)
Microchip Technology
Package: 44-pin TQFP (10 x 10 mm)
Timers: 2 x 8-bit, 3 x 16-bit
Core Architecture: PIC 8-bit RISC

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4221-I/PT

✅ Drop-In
📦 TQFP-44 (10x10 mm)
same die/package, tray packaging (no T suffix)

📋 Reference alternative (not in catalog)

PIC18F4221T-I/ML

✅ Drop-In
Microchip Technology
📦 TQFP-44 (10x10 mm)
PIC18 (8-bit, Harvard RISC) · 77 single-word instructions · 40 MHz (10 MIPS) · 4 KB (2K x 16) · 512 bytes · 256 bytes · Up to 36 · 10-bit, up to 13 channels

✓ In Stock

$2.55 / Unit

View Datasheet →

PIC18F4220-I/P

✅ Drop-In
Microchip Technology
📦 TQFP-44 (10x10 mm)
PIC · 8-Bit · PIC18 · 40 MHz · 10 MIPS · 100 ns · Flash · 4 KB (2K x 16)

✓ In Stock

$4.78 / Unit

View Datasheet →

PIC18F4220T-I/ML

✅ Drop-In
Microchip Technology
📦 TQFP-44 (10x10 mm)
8-bit Microcontroller (MCU) · PIC18F · Enhanced Harvard RISC, 77 instructions · 4 KB · 512 bytes · 256 bytes · 40 MHz (10 MIPS) · 4.2 V to 5.5 V

✓ In Stock

$3.64 / Unit

View Datasheet →

PIC18F4220-E/P

✅ Drop-In
Microchip Technology
📦 TQFP-44 (10x10 mm)
PIC18 8-bit RISC · 4 KB (2K x 16) · 512 bytes · 256 bytes · 25 MHz (10 MIPS) · 4.2 V to 5.5 V · 36 · 10-bit, 13 channels

✓ In Stock

$4.65 / Unit

View Datasheet →

PIC18F4221-I/P

✅ Drop-In
Microchip Technology
📦 TQFP-44 (10x10 mm)
PIC18 (8-bit RISC) · 4 KB (2K x 16) · 512 bytes · 256 bytes · 40 MHz · 16 MIPS (200 ns instruction cycle) · 4.2 V to 5.5 V · 36

✓ In Stock

$3.15 / Unit

View Datasheet →

PIC18F4221T-I/PT Maximum Ratings & Electrical Characteristics

Core Architecture PIC18 (8-bit RISC)
Program Memory (Flash) 4 KB (2K x 16)
Data RAM 512 bytes
EEPROM 256 bytes
Maximum CPU Speed 40 MHz (10 MIPS)
Supply Voltage 4.2 V to 5.5 V
I/O Pins 36
ADC 10-bit, multi-channel
Package 44-pin TQFP (PT) 10x10 mm
Operating Temperature -40C to +85C (Industrial)
Mounting Type Surface Mount
Packaging Tape & Reel (T suffix)
Power-Saving Modes nanoWatt Technology
Timers Multiple 8/16-bit timers
Communication USART, MSSP (I2C/SPI)
Instruction Set 77 single-word instructions
RoHS Status Compliant

PIC18F4221T-I/PT Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 RA2/AN2/VREF- — Port A bit 2 / Analog input 2 / Voltage reference negative
Pin 2 RA3/AN3/VREF+ — Port A bit 3 / Analog input 3 / Voltage reference positive
Pin 3 RA4/T0CKI — Port A bit 4 / Timer0 clock input
Pin 4 RA5/AN4/SS — Port A bit 5 / Analog input 4 / SPI slave select
Pin 5 RA6 — Port A bit 6
Pin 6 RA7 — Port A bit 7
Pin 7 VSS — Ground reference
Pin 8 OSC1/CLKI/RA7 — External oscillator input / Clock input
Pin 9 OSC2/CLKO/RA6 — External oscillator output / Clock output
Pin 10 VDD — Positive supply voltage
Pin 11 MCLR/VPP/RE3 — Master clear reset / Programming voltage / Port E bit 3
Pin 12 RB0/INT0 — Port B bit 0 / External interrupt 0
Pin 13 RB1/INT1 — Port B bit 1 / External interrupt 1
Pin 14 RB2/INT2 — Port B bit 2 / External interrupt 2
Pin 15 RB3/CCP2 — Port B bit 3 / Capture/Compare/PWM 2
Pin 16 RB4 — Port B bit 4
Pin 17 RB5/PGM — Port B bit 5 / Low-voltage programming
Pin 18 RB6/PGC — Port B bit 6 / ICSP clock
Pin 19 RB7/PGD — Port B bit 7 / ICSP data
Pin 20 VSS — Ground reference
Pin 21 VDD — Positive supply voltage
Pin 22 RC0/T1OSO — Port C bit 0 / Timer1 oscillator output
Pin 23 RC1/T1OSI/CCP2 — Port C bit 1 / Timer1 oscillator input / CCP2
Pin 24 RC2/CCP1 — Port C bit 2 / Capture/Compare/PWM 1
Pin 25 RC3/SCK/SCL — Port C bit 3 / SPI clock / I2C clock
Pin 26 RC4/SDI/SDA — Port C bit 4 / SPI data in / I2C data
Pin 27 RC5/SDO — Port C bit 5 / SPI data out
Pin 28 RC6/TX/CK — Port C bit 6 / USART transmit / clock
Pin 29 RC7/RX/DT — Port C bit 7 / USART receive / data
Pin 30 VSS — Ground reference
Pin 31 RD0 — Port D bit 0
Pin 32 RD1 — Port D bit 1
Pin 33 RD2 — Port D bit 2
Pin 34 RD3 — Port D bit 3
Pin 35 RD4 — Port D bit 4
Pin 36 RD5/PSP5 — Port D bit 5 / Parallel slave port bit 5
Pin 37 RD6/PSP6 — Port D bit 6 / Parallel slave port bit 6
Pin 38 RD7/PSP7 — Port D bit 7 / Parallel slave port bit 7
Pin 39 VSS — Ground reference
Pin 40 VDD — Positive supply voltage
Pin 41 RE0/RD/AN5 — Port E bit 0 / Read control / Analog input 5
Pin 42 RE1/WR/AN6 — Port E bit 1 / Write control / Analog input 6
Pin 43 RE2/CS/AN7 — Port E bit 2 / Chip select / Analog input 7
Pin 44 NC — Not connected (per datasheet package variant)

Typical Applications

PIC18F4221T-I/PT is suitable for 7 applications: Industrial Sensor Interface, Low-Power Remote Control, Consumer Appliance Control, HMI Front Panel, Automotive Body and Comfort Module, Battery-Powered Data Logger, Educational and Prototyping Platform.

🏭

Industrial Sensor Interface

The PIC18F4221T-I/PT suits industrial sensor interfaces thanks to its 10-bit ADC, 36 I/O pins, and 4.2-5.5V supply range. Its 40 MHz CPU delivers 10 MIPS, sufficient for sampling multi-channel analog sensors (temperature, pressure, level) at rates up to 100 kS/s aggregate. The 4 KB Flash supports state-machine firmware for sensor linearization and digital filtering. Industrial-grade -40C to +85C operation tolerates factory-floor conditions. nanoWatt power-saving modes enable battery or energy-harvested deployments where the MCU spends most of its time in Sleep, waking only on timer or interrupt. Compared to higher-end Cortex-M0 parts, the PIC18F4221 offers a smaller BOM, mature MPLAB X toolchain, and proven long-term Microchip supply for industrial lifecycle (10+ years).

📱

Low-Power Remote Control

Handheld remote controls benefit from the PIC18F4221T-I/PT's nanoWatt technology, which keeps quiescent current below 1 uA in Sleep mode. The internal oscillator eliminates external crystals for cost reduction, while the 36 I/O pins drive key matrices, IR LEDs, and LCD segments directly. 4 KB Flash is sufficient for protocol stacks (RC5, NEC, SIRC) plus application logic. Supply range of 4.2-5.5V accommodates 2-3 AA cells with a boost converter. Compared to ATmega or STM8 alternatives, the PIC18F4221 offers deeper Sleep modes and Microchip's free MPLAB X IDE plus XC8 compiler. Industrial temperature range ensures operation in automotive cabins and outdoor environments.

🏭

Consumer Appliance Control

Small kitchen and home appliances (coffee machines, blenders, microwave ovens) commonly use the PIC18F4221T-I/PT to drive relays, triacs, keypads, and LED indicators. The 36 I/O pins handle multiple AC zero-cross detection inputs, triac firing outputs, and rotary encoder quadrature inputs. 10 MIPS performance easily runs state-machine firmware for wash cycles, brew profiles, or toast browning algorithms. 4 KB Flash fits typical appliance code, while 256 bytes of EEPROM store user settings and counters. Compared to discrete logic or 8051 designs, the PIC18F4221 reduces BOM cost and PCB area. Industrial temperature grade and Microchip's long-term supply support 7-10 year appliance lifecycles.

📺

HMI Front Panel

Human-machine interface front panels for industrial equipment, instruments, and building automation use the PIC18F4221T-I/PT to scan keypads, drive 7-segment or character LCDs, and communicate with main controllers via USART, I2C, or SPI. 36 I/O pins directly drive 4x4 key matrices and 8-digit displays without external logic. 10 MIPS runs debounce, key encoding, and menu navigation smoothly. The 10-bit ADC reads potentiometers and analog sensors for trim controls. Compared to dedicated LCD controllers, integrating the LCD driver in the PIC18F4221 reduces cost and board space. nanoWatt Sleep supports battery-backed clock and last-state memory in power-outage scenarios.

🚗

Automotive Body and Comfort Module

Automotive body controllers for window lifters, mirror adjusters, seat controllers, and interior lighting use the PIC18F4221T-I/PT. Its industrial -40C to +85C range covers cabin environments, and the 4.2-5.5V supply matches 12V battery rails after regulation. The PIC18F4221E (extended temp) variant handles under-hood conditions. 36 I/O pins drive H-bridge enable lines, current-sense amplifiers, and LIN-bus transceivers. nanoWatt modes support key-off quiescent current budgets below 100 uA per module. Compared to dedicated automotive MCUs, the PIC18F4221 offers lower unit cost for non-safety body applications; safety-critical systems should use AEC-Q100 qualified parts like PIC18F46K22-E/PT.

⚡

Battery-Powered Data Logger

Portable data loggers for environmental monitoring, cold-chain tracking, and field instrumentation leverage the PIC18F4221T-I/PT's nanoWatt Sleep modes (below 1 uA) to extend battery life to months or years. The 10-bit ADC reads temperature, humidity, and voltage sensors; 4 KB Flash buffers compressed measurement packets before bulk transmission. 256 bytes of EEPROM retain calibration constants and session metadata across power cycles. The internal oscillator eliminates crystals, reducing BOM and quiescent draw. Compared to 32-bit ARM Cortex-M0+ alternatives, the PIC18F4221 offers deeper sleep and simpler toolchain. Microchip's long-term supply and stable silicon revision make this part ideal for 5-10 year deployed logger products.

🧩

Educational and Prototyping Platform

Universities, hobbyists, and rapid-prototyping labs use the PIC18F4221T-I/PT for embedded systems courses and proof-of-concept designs because of its mature toolchain, abundant application examples, and forgiving peripheral set. Microchip's free MPLAB X IDE plus XC8 compiler removes licensing friction for students and Makers. 36 I/O pins support breadboard-friendly breakout boards; the 10 MIPS performance comfortably runs real-time demos. Compared to launchpad-style ARM boards, the PIC18F4221 is more affordable in single-unit quantities and provides direct register-level programming experience. The TQFP-44 package requires breakout PCB but enables compact final designs.

Recommended Products Summary

PIC18F4220T-I/ML Microchip Technology Used in: Industrial Sensor Interface MCP9700 Analog temperature sensor (3.3V/5V compatible) Used in: Industrial Sensor Interface MCP4725 12-bit DAC for actuator control Used in: Industrial Sensor Interface PIC18F4221-I/PT Tray-packaged variant Used in: Low-Power Remote Control MCP1640 Boost converter for 2-cell to 5V supply Used in: Low-Power Remote Control, Battery-Powered Data Logger TSOP38238 38 kHz IR receiver module Used in: Low-Power Remote Control PIC18F4221T-I/ML Microchip Technology Used in: Consumer Appliance Control, Battery-Powered Data Logger MOC3021 Optotriac for AC load switching Used in: Consumer Appliance Control MCP23S17 I/O expander for additional buttons/LEDs Used in: Consumer Appliance Control PIC18F4220-I/P Microchip Technology Used in: HMI Front Panel MCP23017 I2C I/O expander for larger keypads Used in: HMI Front Panel HD44780 Character LCD controller compatible via parallel interface Used in: HMI Front Panel PIC18F4220-E/P Microchip Technology Used in: Automotive Body and Comfort Module MCP2551 CAN bus transceiver Used in: Automotive Body and Comfort Module TLE7259-3 LIN bus transceiver Used in: Automotive Body and Comfort Module MCP9808 High-accuracy I2C temperature sensor Used in: Battery-Powered Data Logger PIC18F4221-I/P Microchip Technology Used in: Educational and Prototyping Platform MCP2200 USB-to-UART bridge for PC connectivity Used in: Educational and Prototyping Platform PICkit 3 Microchip in-circuit debugger/programmer Used in: Educational and Prototyping Platform
What is the program memory size of PIC18F4221T-I/PT?
The PIC18F4221T-I/PT has 4 KB (2K x 16) of in-circuit self-programmable Flash program memory, according to the Microchip datasheet. This is sufficient for small to medium embedded applications such as sensor controllers, simple user interfaces, and low-speed communication tasks. 512 bytes of RAM and 256 bytes of EEPROM complement the Flash for data and configuration storage.
What is the maximum operating frequency of PIC18F4221T-I/PT?
The PIC18F4221T-I/PT operates at a maximum CPU clock of 40 MHz, delivering up to 10 MIPS (100 ns instruction execution). For lower-power designs, internal oscillator blocks can be configured to lower frequencies, supporting nanoWatt power-saving modes. This speed class is typical of PIC18F microcontrollers aimed at general-purpose 8-bit embedded tasks.
What package does the PIC18F4221T-I/PT use?
The PIC18F4221T-I/PT is housed in a 44-pin TQFP (Thin Quad Flat Pack) measuring 10x10 mm. The "T" suffix denotes Tape & Reel packaging for high-volume assembly. The PT package offers 36 usable I/O pins and is suitable for industrial temperature operation from -40C to +85C. Always verify PCB footprint against the TQFP-44 10x10 mm land pattern before layout finalization.
Where can I buy PIC18F4221T-I/PT online?
The PIC18F4221T-I/PT is in stock at DigiKey, Mouser, LCSC Electronics, RS-Online, and Microchip USA as of 2026-09-27. XAIPART also lists this part with tiered pricing from qty-1 unit price (USD 3.10) down to volume breaks at 1000 pieces (USD 1.82). Lead time for tape-and-reel quantities of 1000+ is typically 4-6 weeks from authorized distributors.
What is the price of PIC18F4221T-I/PT?
The PIC18F4221T-I/PT lists at USD 3.10 for qty-1 as of 2026-09-27, dropping to USD 1.82 at qty-1000. LCSC reports pricing from USD 1.8198 in volume. Authorized distributor pricing (DigiKey, Mouser) tends to be slightly higher but includes traceability and warranty. For OEM volume contracts, contact Microchip directly for the latest rebate schedule.
What is the lead time for PIC18F4221T-I/PT?
Lead time for the PIC18F4221T-I/PT is currently 8-12 weeks from Microchip factory for non-stocked tape-and-reel volumes, per 2026-09-27 distributor data. Smaller reels (100-1000 pieces) typically ship from regional distributor stock within 1-3 business days. For prototype quantities, XAIPART and DigiKey maintain inventory suitable for engineering builds.
Is PIC18F4221T-I/PT in stock?
Yes, the PIC18F4221T-I/PT is in stock at LCSC, DigiKey, Mouser, and RS-Online as of 2026-09-27. Mouser and DigiKey typically carry 1000-5000 piece reels, while LCSC maintains smaller reel sizes for prototyping. Check the XAIPART product page for the latest live stock level and tiered pricing specific to this component.
PIC18F4221T-I/PT vs PIC18F4221-I/PT - what is the difference?
The PIC18F4221T-I/PT and PIC18F4221-I/PT are the same die and same TQFP-44 package, differing only in shipping media: the "T" suffix denotes Tape & Reel packaging, while the non-T version ships in trays. Both share the same -40C to +85C temperature range, 40 MHz CPU, and 4 KB Flash. They are drop-in interchangeable on the PCB; pick the suffix that matches your assembly process.
Can PIC18F4220-I/P replace PIC18F4221T-I/PT?
No, the PIC18F4220-I/P cannot be a drop-in replacement for the PIC18F4221T-I/PT because the packages differ: the 4220 variant uses PDIP-40, while the 4221T uses TQFP-44. They share the same PIC18F core and footprint philosophy but require PCB rework. Use the PIC18F4221T-I/ML variant (TQFP-44 8x8 mm) only if your board accepts a smaller footprint - otherwise stay on the 4221 family in TQFP-44.
When should I choose PIC18F4221T-I/PT over PIC18F45K22?
Choose the PIC18F4221T-I/PT for cost-sensitive 5V designs with 4 KB Flash and nanoWatt power savings; choose the PIC18F45K22 for higher performance (64 MHz), more Flash (32 KB), and 2.0-5.5V wide-supply operation. Both use the PIC18 architecture, so code is portable with minor register changes, but the package differs (TQFP-44 vs TQFP-44 / 64-pin) - verify pinout before swapping.
What is the best drop-in replacement for PIC18F4221T-I/PT?
The best drop-in replacement is the PIC18F4221T-I/ML (TQFP-44 but in an 8x8 mm package, not the same footprint) or the non-T PIC18F4221-I/PT (same die, same TQFP-44 10x10 mm, tray packaging). For a same-footprint alternative from the same family with more memory, consider the PIC18F4620-I/PT - but check the pinout, as the 4620 has additional peripherals that may require firmware updates.
What is a cross-brand equivalent for PIC18F4221T-I/PT?
There is no direct cross-brand drop-in replacement for the PIC18F4221T-I/PT because Microchip's PIC18F architecture is proprietary. Cross-brand 8-bit MCU alternatives from Atmel/Microchip (ATmega series), STMicroelectronics (STM8), or NXP (LPC1100) share similar TQFP-44 packages and Flash footprints but require code rewrite, register mapping changes, and toolchain porting - they are not drop-in. Plan for firmware work if switching architectures.
Where to download PIC18F4221T-I/PT datasheet PDF?
The PIC18F4221T-I/PT datasheet (document 39609E) is available as a free PDF download from Microchip's product page at microchip.com and from third-party aggregators including DigiKey, Mouser, FindIC, and LCSC. The datasheet contains the full pinout, electrical characteristics, instruction set summary, and peripheral configuration registers. As of 2026-09-27, the latest revision is available at the Microchip document portal.
Where to find PIC18F4221T-I/PT pinout?
The PIC18F4221T-I/PT pinout is documented on page 8 of the Microchip datasheet (document 39609E). The 44-pin TQFP provides 36 bidirectional I/O pins, plus supply, ground, MCLR, and oscillator pins. A pinout diagram is also rendered on the XAIPART product page alongside the package SVG. Always cross-reference the datasheet pinout against your schematic before PCB layout finalization.
What are the key specifications of PIC18F4221T-I/PT that engineers should know?
The PIC18F4221T-I/PT delivers 40 MHz CPU clock (10 MIPS), 4 KB Flash, 512 B RAM, 256 B EEPROM, 10-bit ADC, 36 I/O, USART, MSSP (I2C/SPI), and nanoWatt power-saving modes per the Microchip datasheet (document 39609E). Supply voltage is 4.2-5.5V and operating temperature is -40C to +85C industrial. The TQFP-44 package measures 10x10 mm and ships in tape-and-reel format. These parameters cover most cost-sensitive 8-bit embedded designs in industrial and consumer applications.

Engineering reference data for PIC18F4221T-I/PT — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC18F4221T-I/PT when you need a cost-optimized 8-bit PIC microcontroller with 4 KB Flash, 10 MIPS performance, and tape-and-reel packaging for automated SMT assembly. It is well suited for industrial, consumer, and automotive body applications in the -40C to +85C range. Pick the PIC18F4221-I/PT for tray packaging suitable for prototyping or low-volume production with manual assembly. Choose the PIC18F4221T-I/ML if you must minimize PCB area and can accept the 8x8 mm package's tighter design rules. For under-hood automotive or harsh-temperature environments, select the PIC18F4220-E/P (extended -40C to +125C). All five variants share the same PIC18F core, instruction set, and peripheral architecture, so firmware is portable across the family with only minor register changes. The PIC18F4221 is preferred over the PIC18F4220 when you need additional ADC channels or specific peripheral features documented in the 4221 datasheet.

Comparison with Alternatives

Parameter This Product PIC18F4221-I/PT PIC18F4221T-I/ML PIC18F4220-I/P PIC18F4220T-I/ML PIC18F4220-E/P
Package TQFP-44 (PT) 10x10 mm TQFP-44 10x10 mm - same TQFP-44 8x8 mm - smaller TQFP-44 10x10 mm - same TQFP-44 8x8 mm - smaller TQFP-44 10x10 mm - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core PIC18F 8-bit PIC18F 8-bit PIC18F 8-bit PIC18F 8-bit PIC18F 8-bit PIC18F 8-bit
Flash Memory 4 KB 4 KB 4 KB 4 KB 4 KB 4 KB
RAM 512 B 512 B 512 B 512 B 512 B 512 B
Max CPU Speed 40 MHz 40 MHz 40 MHz 40 MHz 40 MHz 40 MHz
Operating Temperature -40C to +85C (I) -40C to +85C (I) -40C to +85C (I) -40C to +85C (I) -40C to +85C (I) -40C to +125C (E)
Packaging Tape & Reel Tray Tape & Reel Tray Tape & Reel Tray
I/O Pins 36 36 36 36 36 36
Approx. Unit Price (USD) 3.10 3.05 3.15 2.90 2.95 3.85

Key Differentiators

  • Tape & Reel packaging for high-volume assembly (vs PIC18F4221-I/PT)
  • Industrial temperature range as standard (vs PIC18F4220-E/P)
  • TQFP-44 10x10 mm footprint with full peripheral set (vs PIC18F4221T-I/ML (TQFP-44 8x8 mm))

Design Notes

Place a 100 nF decoupling capacitor as close as possible (within 5 mm) to each VDD pin (pins 10, 21, 40). Add a bulk 10 uF tantalum or aluminum polymer capacitor at the board supply entry. For battery-powered designs, route VDDCORE (if exposed) through a ferrite bead from VDD to reduce digital switching noise coupling into the analog supply. Verify brown-out reset (BOR) configuration matches your supply ramp profile - the default BOR at 4.0V may reset the part on slow 5V rails.

The TQFP-44 10x10 mm package has a 0.8 mm pitch and a 12x12 mm land pattern with thermal pad optional. Route all I/O signals on the top layer to keep via count low; use a continuous ground plane on the bottom layer to provide return paths and reduce EMI. Keep the ICSP pins (RB6/PGC, RB7/PGD) accessible for in-circuit programming without removing the MCU from the board - this allows firmware updates in production. Maintain at least 0.2 mm clearance between traces and package pads to avoid solder bridge defects at assembly.

Do not leave MCLR floating - tie it to VDD through a 10 kohm resistor, with a 100 nF capacitor to ground for noise filtering. Floating MCLR is the most common cause of spurious resets in 8-bit PIC designs. Also configure the CONFIG register for the correct oscillator mode (HS, XT, or internal RC) before code execution - an unconfigured part may fail to start. Finally, when using ADC, ensure the acquisition time exceeds 1.4 us at 40 MHz and that source impedance stays below 2.5 kohm to avoid ADC accuracy degradation.

Estimated: The PIC18F4221T-I/PT dissipates approximately 50 mA * 5V = 250 mW at full CPU load (40 MHz with all peripherals active). The TQFP-44 package has a junction-to-ambient thermal resistance (theta_JA) of approximately 50 C/W on a standard 4-layer JEDEC test board, yielding a temperature rise of 12.5 C above ambient. For most industrial applications this is well within the -40C to +85C operating range; however, in sealed enclosures with no airflow, derate clock speed to 20 MHz or add thermal vias under the exposed pad (if used). Always measure the actual junction temperature in your final enclosure.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page. Standard industrial grade (I suffix, -40C to +85C) - not AEC-Q100 qualified. For AEC-Q100 automotive applications, choose PIC18F46K22-E/PT or PIC18F4620-I/PT (automotive-grade variants).

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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