Microchip Technology

PIC18F4320-E/ML - 8-bit MCU, 8KB Flash, 44-QFN | Microchip

MPN: PIC18F4320-E/ML ✓ Active
In Stock Ships in 1-3 business days
2.0 V to 5.5 V Vdss 44-QFN (8x8 mm) with exposed thermal pad Package 25 MHz (40 MHz on selected speed grades) Speed Flash Memory
From $4.1 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $6.42 $6.42
10 $5.78 $57.80
100 $5.16 $516.00
500 $4.61 $2,305.00
1,000 $4.1 $4,100.00
ℹ️ All prices are in USD

PIC18F4320-E/ML Overview

The Microchip Technology PIC18F4320-E/ML is an 8-bit PIC microcontroller in the PIC18F family, integrating 8 KB of Flash program memory, 512 bytes of SRAM, and 256 bytes of EEPROM in a 44-pin QFN (8x8 mm) package with exposed thermal pad. It executes instructions at up to 25 MHz (40 MHz max on selected speed grades), delivering 10 MIPS while operating from 2.0 V to 5.5 V across the industrial temperature range of -40C to +125C.

A microcontroller (MCU) is a single-chip computer containing a CPU core, program and data memory, and integrated peripherals such as timers, ADC, communication ports, and GPIO. The PIC18F family sits at the upper end of Microchip's 8-bit portfolio, offering an enhanced instruction set with C-friendly addressing, prioritized interrupts, and a 16-bit instruction word. Within the wider taxonomy, MCUs belong to embedded computing, which sits below microprocessors in the system hierarchy; the PIC18F family targets cost-sensitive real-time control rather than high-throughput digital signal processing.

Key features include 36 digital I/O pins, 13 channels of 10-bit Analog-to-Digital converter (ADC), 2 analog comparators, 2 Capture/Compare/PWM modules, a master Synchronous Serial Port configurable as SPI or I2C, an Addressable Universal Asynchronous Receiver/Transmitter (AUSART), and self-programming Flash with In-Circuit Debug support. The device supports 1,000,000 erase/write cycles on Flash and 100,000 cycles on EEPROM, with 40-year data retention. The 'E' suffix indicates the extended (-40C to +125C) industrial temperature range, while the 'ML' suffix designates the 44-lead QFN package.

The PIC18F4320 uses a Harvard RISC architecture with separate program and data buses, hardware multiply, and a 31-level stack, enabling deterministic real-time response. The 10-bit ADC integrates with the analog comparators for sensor conditioning, while the ECCP and CCP modules generate PWM for motor and power control. Self-programmability allows field firmware updates without an external programmer.

Typical applications include industrial control, automotive body electronics, sensor interfacing, low-end motor control, and consumer appliances. The 44-QFN package suits space-constrained designs requiring up to 36 GPIO plus analog and serial connectivity. The PIC18F4320 pairs naturally with the PIC18F4220/4520 family siblings for upgrade/downgrade flexibility within the same 44-QFN footprint.

When designing with this MCU, ensure adequate decoupling (100 nF ceramic per VDD pin) and route the exposed thermal pad to a continuous ground plane for thermal dissipation and low-impedance ground return. Verify ICP/ICD pin assignments against Microchip's programming specification to avoid debugger conflicts in production units.

This page synthesizes distributor pricing, verified drop-in alternatives, and practical design notes not found in the bare manufacturer datasheet.

Drop-in alternatives for PIC18F4320-E/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F4320-E/ML (same form factor and footprint) — differing in Package, Core Architecture, Operating Temperature, Power-Saving Modes, ADC.

Microchip Technology
Package: 44-pin VQFN (Exposed Pad), 8x8 mm
Core Architecture: PIC18 (8-bit RISC, 16-bit instruction word)
Operating Temperature: -40 C to +125 C (E grade)
Microchip Technology
Package: PDIP-40 (DIP-40, 0.600 in / 15.24 mm)
Core Architecture: PIC18 (8-bit RISC, Harvard bus)
Power-Saving Modes: nanoWatt (Run / Idle / Sleep)
Microchip Technology
Package: 44-VQFN with exposed pad (8x8 mm)
Core Architecture: PIC 8-bit RISC
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: 44-pin QFN (8x8 mm) with exposed pad
Operating Temperature: -40C to +125C (E grade, extended)
Power-Saving Modes: nanoWatt technology (Run, Idle, Sleep)
Microchip Technology
Package: QFN-44 (8x8 mm) with exposed thermal pad
Core Architecture: PIC18 8-bit Harvard RISC
Operating Temperature: -40C to +125C (E grade)
Microchip Technology
Package: 44-pin QFN (8x8 mm, exposed pad)
Core Architecture: PIC 8-bit RISC (enhanced Harvard)
Operating Temperature: -40 C to +125 C (Extended, -E grade)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4520-E/ML

✅ Drop-In
Microchip Technology
📦 44-QFN (8x8 mm)
PIC® 18F · PIC 8-bit RISC (enhanced Harvard) · 8-bit · 25 MHz (40 MHz input / 10 MIPS) · 32 KB Flash (16K x 16) · 1536 bytes · 256 bytes · 36

✓ In Stock

$2.78 / Unit

View Datasheet →

PIC18F4220-E/ML

✅ Drop-In
Microchip Technology
📦 44-QFN (8x8 mm)
PIC18 (8-bit RISC, 16-bit instruction word) · 4 KB (2K x 16) · 512 bytes · 256 bytes · 40 MHz / 10 MIPS · 36 · 13 channels x 10-bit

✓ In Stock

$4.62 / Unit

View Datasheet →

PIC18F4320-I/ML

✅ Drop-In
📦 44-QFN (8x8 mm)
same die, commercial/industrial -40C to +85C temperature range vs -40C to +125C extended

📋 Reference alternative (not in catalog)

PIC18F4320-E/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 44-QFN (8x8 mm)
PIC18 (8-bit RISC, Harvard bus) · 8 KB (4K x 16 words) · 512 bytes · 256 bytes · 40 MHz · 10 MIPS · 4.2 V to 5.5 V · 36

✓ In Stock

$2.95 / Unit

View Datasheet →

PIC18F4420-I/ML

✅ Drop-In
📦 44-QFN (8x8 mm)
same 44-QFN footprint, 16 KB Flash vs 8 KB (+100%), 768 B RAM vs 512 B (+50%), pin-to-pin compatible upgrade

📋 Reference alternative (not in catalog)

PIC18F4320-E/ML Maximum Ratings & Electrical Characteristics

Core Processor PIC
Core Size 8-bit
Max CPU Speed 25 MHz (40 MHz on selected speed grades)
Program Memory Type Flash
Program Memory Size 8 KB (4K x 16)
RAM Size 512 bytes
EEPROM Size 256 bytes
Number of I/O 36
Package 44-QFN (8x8 mm) with exposed thermal pad
Supply Voltage Range 2.0 V to 5.5 V
Operating Temperature Range -40C to +125C (E suffix = extended industrial)
ADC 10-bit, 13 channels
Comparators 2 analog comparators
PWM / CCP / ECCP 2 Capture/Compare/PWM modules
Communication SPI, I2C (MSSP), AUSART
Mounting Type Surface Mount
RoHS Status Compliant
Lead-Free Yes

PIC18F4320-E/ML Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 OSC1/CLKI/RA7 — Oscillator crystal input / external clock / GPIO RA7
Pin 2 OSC2/CLKO/RA6 — Oscillator crystal output / clock out / GPIO RA6
Pin 3 MCLR/VPP/RE3 — Master Clear (reset) / programming voltage / GPIO RE3
Pin 4 RA0/AN0 — GPIO RA0 / analog input AN0
Pin 5 RA1/AN1 — GPIO RA1 / analog input AN1
Pin 6 RA2/AN2/VREF- — GPIO RA2 / analog input AN2 / ADC VREF-
Pin 7 RA3/AN3/VREF+ — GPIO RA3 / analog input AN3 / ADC VREF+
Pin 8 RA4/AN4/T0CKI — GPIO RA4 / analog AN4 / Timer0 clock input
Pin 9 RA5/AN5/SS/LVDIN — GPIO RA5 / AN5 / SPI slave select / LVD input
Pin 10 VSS — Ground reference
Pin 11 VDD — Positive supply voltage (2.0-5.5 V)
Pin 12 RB0/AN12/INT0 — GPIO RB0 / AN12 / external interrupt 0
Pin 13 RB1/AN10/INT1 — GPIO RB1 / AN10 / external interrupt 1
Pin 14 RB2/AN8/INT2 — GPIO RB2 / AN8 / external interrupt 2
Pin 15 RB3/AN9/CCP2A — GPIO RB3 / AN9 / CCP2 PWM output A
Pin 16 RB4/AN11 — GPIO RB4 / analog AN11
Pin 17 RB5/CCP3A — GPIO RB5 / CCP3 PWM output A
Pin 18 RB6/PGC — GPIO RB6 / ICSP clock (ICD clock)
Pin 19 RB7/PGD — GPIO RB7 / ICSP data (ICD data)
Pin 20 VSS — Ground reference
Pin 21 VDD — Positive supply voltage (2.0-5.5 V)
Pin 22 RC0/T1OSO/T1CKI — GPIO RC0 / Timer1 oscillator out / Timer1 clock in
Pin 23 RC1/T1OSI/CCP2B — GPIO RC1 / Timer1 oscillator in / CCP2 PWM output B
Pin 24 RC2/CCP1 — GPIO RC2 / CCP1 PWM
Pin 25 RC3/SCK/SCL — GPIO RC3 / SPI clock / I2C clock
Pin 26 RC4/SDI/SDA — GPIO RC4 / SPI data in / I2C data
Pin 27 RC5/SDO — GPIO RC5 / SPI data out
Pin 28 RC6/TX/CK — GPIO RC6 / AUSART TX / clock
Pin 29 RC7/RX/DT — GPIO RC7 / AUSART RX / data
Pin 30 VSS — Ground reference
Pin 31 VDD — Positive supply voltage (2.0-5.5 V)
Pin 32 RD0/PSP0 — GPIO RD0 / parallel slave port bit 0
Pin 33 RD1/PSP1 — GPIO RD1 / parallel slave port bit 1
Pin 34 RD2/PSP2 — GPIO RD2 / parallel slave port bit 2
Pin 35 RD3/PSP3 — GPIO RD3 / parallel slave port bit 3
Pin 36 RD4/PSP4 — GPIO RD4 / parallel slave port bit 4
Pin 37 RD5/PSP5 — GPIO RD5 / parallel slave port bit 5
Pin 38 RD6/PSP6 — GPIO RD6 / parallel slave port bit 6
Pin 39 RD7/PSP7 — GPIO RD7 / parallel slave port bit 7
Pin 40 VSS — Ground reference
Pin 41 VDD — Positive supply voltage (2.0-5.5 V)
Pin 42 RE0/RD/AN5 — GPIO RE0 / parallel read / AN5
Pin 43 RE1/WR/AN6 — GPIO RE1 / parallel write / AN6
Pin 44 RE2/CS/AN7 — GPIO RE2 / parallel chip select / AN7

Typical Applications

PIC18F4320-E/ML is suitable for 6 applications: Industrial Sensor Interface, Automotive Body Electronics, Low-End Motor Control (BLDC / Stepper), Consumer Appliance Control, Data Acquisition / Instrumentation Front-End, Home Automation / IoT Edge Node.

🏭

Industrial Sensor Interface

The PIC18F4320-E/ML is well suited for industrial sensor hubs that aggregate multiple analog and digital signals. Its 13-channel 10-bit ADC directly samples thermistor bridges, pressure transducers, and 4-20 mA loop signals with no external multiplexer, while the 2 analog comparators handle threshold detection for over-temperature or over-current events. With 36 GPIO the MCU can also drive status LEDs and read push-buttons or rotary switches, eliminating a glue-logic ASIC. Running at 25 MHz with the AUSART, the device streams conditioned data to a host PLC or HMI at 115.2 kbps. The extended -40C to +125C temperature range and 2.0-5.5 V supply tolerance make it compatible with 24 V industrial rails after regulation.

🚗

Automotive Body Electronics

Within automotive body modules such as door controllers, seat controllers, and lighting drivers, the PIC18F4320-E/ML delivers the right mix of analog integration and PWM channels. The 2 CCP/ECCP modules generate PWM for LED dimming or mirror-position servo control, while the 13-channel ADC monitors battery voltage, switch states, and motor current. Its extended industrial temperature range handles under-hood and cabin thermal stress, and the self-programming Flash supports OEM firmware updates during service. The MSSP serves SPI peripherals such as LED drivers or I2C sensors. Although not AEC-Q100 qualified, the part is widely used in non-safety automotive body functions where extended temperature operation is sufficient.

⚡

Low-End Motor Control (BLDC / Stepper)

The PIC18F4320-E/ML controls small brushless DC and stepper motors in appliance fans, pumps, and small-format robotics. Its 2 CCP/ECCP modules generate complementary PWM with dead-band control, while the 13-channel ADC samples back-EMF or phase current for sensorless commutation. The 25 MHz / 10 MIPS throughput is sufficient for FOC or trapezoidal commutation of motors up to several hundred watts. Six of the 36 GPIO can be dedicated to high-current gate-driver control. EEPROM stores calibration and ramp profiles, allowing identical hardware to support multiple motor SKUs without firmware re-flash in production.

📱

Consumer Appliance Control

White-goods appliances - washing machines, dishwashers, refrigerators, and air-conditioner indoor units - are a natural fit for the PIC18F4320-E/ML. The MCU drives user-interface keypads and 7-segment or character LCDs, runs the main wash/refrigeration cycle state machine, and interfaces to triac-driven heater or compressor loads via optocouplers. The 256-byte EEPROM preserves user settings (temperature, mode, timer) across power cycles, while 512 bytes of RAM is sufficient for a 32-step cycle descriptor. The extended temperature grade survives compressor compartment thermal swings, and the 44-QFN compact footprint frees PCB area for relay and triac footprints.

🔬

Data Acquisition / Instrumentation Front-End

Portable and bench-top data-acquisition front-ends benefit from the PIC18F4320-E/ML's 13-channel 10-bit ADC, generous SRAM, and on-chip EEPROM for calibration constants. The MSSP provides SPI or I2C to external high-precision ADCs or DACs, while the AUSART streams acquired samples to a host PC. The device's deterministic interrupt latency and 8-bit instruction set make it suitable for sequencing multi-channel sweeps at known sample rates. The exposed thermal pad of the 44-QFN keeps junction temperature low during continuous ADC conversion, improving measurement repeatability in calibration environments.

🧩

Home Automation / IoT Edge Node

The PIC18F4320-E/ML acts as an edge node in home-automation installations where on-board intelligence outweighs wireless complexity. It reads wall switches, dimmer sliders, and contact sensors, drives local relays, and communicates with a central hub via RS-485, I2C, or simple UART protocols. The 36 GPIO handle multi-zone lighting without external expanders, and the 256-byte EEPROM stores zone configuration and last-known states for power-loss recovery. The AUSART and MSSP run Modbus-RTU or DMX512 protocols used in residential lighting and HVAC control. The extended temperature grade supports outdoor junction boxes and garage-mounted control panels.

Recommended Products Summary

PIC18F4520-E/ML Microchip Technology Used in: Industrial Sensor Interface, Automotive Body Electronics, Low-End Motor Control (BLDC / Stepper), Consumer Appliance Control, Data Acquisition / Instrumentation Front-End, Home Automation / IoT Edge Node PIC18F4220-I/ML Microchip Technology Used in: Industrial Sensor Interface MCP2551 CAN transceiver for industrial fieldbus Used in: Industrial Sensor Interface, Automotive Body Electronics, Home Automation / IoT Edge Node MCP2515 Standalone CAN controller for body network Used in: Automotive Body Electronics MCP8024 3-phase BLDC gate driver companion Used in: Low-End Motor Control (BLDC / Stepper) MCP6L01 Op-amp for current-sense amplification Used in: Low-End Motor Control (BLDC / Stepper) MCP23008 I2C GPIO expander for keypad scanning Used in: Consumer Appliance Control MCP1700 Low-Iq LDO for standby supply Used in: Consumer Appliance Control, Home Automation / IoT Edge Node MCP3421 18-bit delta-sigma ADC for precision channels Used in: Data Acquisition / Instrumentation Front-End MCP4725 12-bit DAC for stimulus generation Used in: Data Acquisition / Instrumentation Front-End
What is the program memory size of PIC18F4320-E/ML?
The PIC18F4320-E/ML integrates 8 KB (4K x 16) of Flash program memory with self-programming support. According to the Microchip PIC18F4320 datasheet, the Flash supports 1,000,000 erase/write cycles minimum and 40-year data retention, which is well suited for field-updatable firmware in industrial and embedded designs.
What is the maximum operating frequency of PIC18F4320?
The PIC18F4320 executes instructions at up to 25 MHz, delivering up to 10 MIPS at 5 V. On selected speed grades the device is also rated for 40 MHz operation. The 'E' temperature suffix does not change the speed rating but extends the operating range to -40C to +125C for industrial-grade deployments.
What package does PIC18F4320-E/ML use?
The PIC18F4320-E/ML uses a 44-lead QFN package (also called 44-MLF or 44-VQFN-EP) measuring 8x8 mm with an exposed thermal pad. The exposed pad must be soldered to a continuous ground plane for thermal dissipation and electrical performance. The 'ML' suffix is Microchip's package code for this QFN variant.
How much RAM and EEPROM does PIC18F4320 have?
The PIC18F4320 contains 512 bytes of SRAM and 256 bytes of data EEPROM. The EEPROM supports 100,000 erase/write cycles minimum and 40-year retention, allowing non-volatile storage of user parameters, calibration constants, and serial numbers without external EEPROM chips.
What peripherals are integrated in PIC18F4320?
According to Microchip's PIC18F4320 datasheet, the MCU integrates 13 channels of 10-bit ADC, 2 analog comparators, 2 Capture/Compare/PWM (CCP/ECCP) modules, a Master SSP configurable as SPI or I2C, and an Enhanced USART (AUSART). 36 digital I/O pins support mixed analog and digital signal acquisition.
Where can I buy PIC18F4320-E/ML online?
The PIC18F4320-E/ML is in stock at major authorized distributors including DigiKey, Mouser, and Microchip Direct as of 2026-09-27. It ships in tube packaging (61 per tube) for prototype quantities and tape-and-reel (T/R) for production. Lead time is generally 8-12 weeks from the factory for large volumes.
What is the price of PIC18F4320-E/ML?
As of 2026-09-27, the PIC18F4320-E/ML unit price is approximately USD 6.42 at qty 1, dropping to USD 4.10 at qty 1000. Pricing varies slightly by distributor and reel orientation; Mouser and DigiKey both list authorized stock. For larger production volumes request a quote from Microchip Direct.
What is the lead time for PIC18F4320-E/ML?
Lead time for PIC18F4320-E/ML at authorized distributors is typically 8-12 weeks from Microchip's factory for volumes above 1,000 units, as of 2026-09-27. Small prototype quantities (under 100) are usually available off-the-shelf at DigiKey and Mouser with same-day shipping.
Is PIC18F4320 still active in Microchip's portfolio?
Yes, as of 2026-09-27 the PIC18F4320 is in active production status per Microchip's product lifecycle page. The 'E' temperature suffix remains an active orderable part. Microchip has continued to invest in the PIC18F family because of its installed base in industrial and automotive control.
Where to download PIC18F4320 datasheet PDF?
The official PIC18F4320 datasheet (document family 39625) can be downloaded as PDF from Microchip's website at ww1.microchip.com/downloads/en/DeviceDoc/39625e.pdf. The datasheet contains full electrical characteristics, peripheral descriptions, instruction set summary, and packaging information for the PIC18F4320 family.
PIC18F4320-E/ML vs PIC18F4320-I/ML - what is the difference?
The PIC18F4320-E/ML uses the 'E' (extended) temperature grade rated -40C to +125C, while the PIC18F4320-I/ML uses the 'I' (industrial) grade rated -40C to +85C. Both share the same 44-QFN footprint, 8 KB Flash, 512 byte SRAM, and pin-for-pin compatibility. Choose 'E' for automotive or harsh industrial, 'I' for standard commercial/industrial.
Can I use PIC18F4520 as a drop-in replacement for PIC18F4320?
The PIC18F4520 has 32 KB Flash and 1.5 KB RAM, double the program memory and three times the SRAM of the PIC18F4320, and shares the same 44-QFN pinout. It is a valid drop-in upgrade on the same PCB footprint. Use PIC18F4520-I/ML for standard temperature, or PIC18F4520-E/ML for extended industrial.
What is the best drop-in replacement for PIC18F4320-E/ML?
The best drop-in replacement is PIC18F4520-E/ML, which shares the same 44-QFN package and pinout while offering 32 KB Flash and 1.5 KB RAM - an upgrade for most applications. For a downward migration within the same family footprint, use PIC18F4220-E/ML with 4 KB Flash. Both are Microchip same-package variants.
When should I choose PIC18F4320 over PIC18F4520?
Choose PIC18F4320 when your firmware fits within 8 KB Flash and 512 bytes RAM and you need cost optimization; the PIC18F4320 is priced lower than the 4520. Choose PIC18F4520 when you need headroom for growth, larger protocol stacks (USB, TCP/IP), or more RAM-intensive buffering. Both share the 44-QFN package.
What are the key specifications of PIC18F4320 that engineers should know?
Engineers working with the PIC18F4320 should know: 8 KB Flash, 512 byte SRAM, 256 byte EEPROM, 25 MHz CPU (10 MIPS), 13-channel 10-bit ADC, 2 comparators, 2 CCP/ECCP PWM, MSSP for SPI/I2C, AUSART, 36 GPIO, 2.0-5.5 V supply, -40C to +125C extended industrial grade, 44-QFN (8x8 mm) package. These define its target applications.
Is PIC18F4320-E/ML RoHS and REACH compliant?
Yes, the PIC18F4320-E/ML is RoHS compliant and lead-free per Microchip's product environmental compliance documentation, as of 2026-09-27. REACH compliance status is published in Microchip's material declaration database. The 'ML' package suffix confirms Pb-free plating and matte-tin lead finish suitable for lead-free reflow profiles.
Which development tools support PIC18F4320 programming?
The PIC18F4320 is supported by Microchip's MPLAB X IDE, XC8 C compiler, and ICD/PICkit in-circuit debuggers (ICD 3, ICD 4, PICkit 3, PICkit 4, Snap). Code examples and application notes are available from Microchip's developer help portal. The device also supports self-programming for bootloader-based field updates.

Engineering reference data for PIC18F4320-E/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC18F4320-E/ML when you need an 8-bit MCU with extended industrial temperature range, 8 KB Flash, 512 byte SRAM, 36 GPIO, and 13-channel 10-bit ADC in a compact 44-QFN footprint - a strong fit for sensor interfaces, low-end motor control, and appliance control. Choose the PIC18F4520-E/ML when your firmware exceeds 8 KB Flash (e.g. USB stacks or graphics), since it shares the same 44-QFN footprint and pinout but offers 32 KB Flash and 1.5 KB RAM. Choose the PIC18F4220-E/ML when you want a 4 KB Flash cost-down for simple control loops in the same package. Choose the PIC18F4320-I/ML only when operating below 85 C is acceptable (commercial/indoor industrial). For automotive safety-critical designs requiring AEC-Q100, look at PIC18FxxK80 family members instead.

Comparison with Alternatives

Parameter This Product PIC18F4520-E/ML PIC18F4220-E/ML PIC18F4320-I/ML PIC18F4420-I/ML
Package 44-QFN (8x8 mm) 44-QFN (8x8 mm) - same 44-QFN (8x8 mm) - same 44-QFN (8x8 mm) - same 44-QFN (8x8 mm) - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Flash Memory 8 KB 32 KB 4 KB 8 KB (identical) 16 KB
SRAM 512 bytes 1536 bytes 512 bytes 512 bytes (identical) 768 bytes
EEPROM 256 bytes 256 bytes 256 bytes 256 bytes (identical) 256 bytes
Max CPU Speed 25 MHz 25 MHz 25 MHz 25 MHz 25 MHz
ADC Channels 13 (10-bit) 13 (10-bit) 13 (10-bit) 13 (10-bit) 13 (10-bit)
Temperature Range -40C to +125C (E) -40C to +125C (E) -40C to +125C (E) -40C to +85C (I) -40C to +85C (I)
GPIO Count 36 36 36 36 36

Key Differentiators

  • Industry-standard 8-bit PIC18 architecture with C-friendly instruction set (vs PIC16F series)
  • 44-QFN compact footprint with 36 GPIO plus 13 ADC channels (vs PIC18F2520/2523 (28-pin SOIC variants))
  • Extended industrial -40C to +125C temperature grade (vs PIC18F4320-I/ML)
  • Self-programming Flash with 1M erase/write cycles (vs External EEPROM storage for firmware parameters)

Design Notes

The PIC18F4320-E/ML has four VDD pins (11, 21, 31, 41) and four VSS pins (10, 20, 30, 40). Place a 100 nF ceramic decoupling capacitor as close as possible to each VDD/VSS pair. For noisy environments (motor control, relay boards) add a bulk 10 uF tantalum or polymer capacitor near the package. Keep analog and digital VDD traces separated if possible, joining them only at a single point to reduce digital switching noise coupling into the ADC reference.

The 44-QFN package exposes a metal pad on its underside (pin 'EP'). This pad is the primary thermal path to the PCB and must be soldered to a continuous ground copper plane of at least 1 square inch. With the EP properly soldered, theta_JA falls from approximately 35 C/W (no EP) to under 20 C/W, enabling full-speed operation in enclosed industrial enclosures. Without proper EP soldering, the junction temperature may exceed 125 C at high ambient.

Route the ICSP pins RB6/PGC and RB7/PGD with short traces to a programming header or test pad. Do NOT populate external pull-ups on these pins because the ICD/PICkit debugger uses its own drive scheme. Place a 10 kohm pull-up on MCLR for normal operation. If you use an in-circuit debugger, route PGC/PGD as a twisted pair or with ground on adjacent layers to avoid noise injection during live debugging of high-speed ADC sequences.

Do not leave unused I/O pins floating. Configure all unused pins as outputs driving low, or as inputs with the internal weak pull-up enabled (RBPU cleared, individual WPUx set). Floating pins can cause excess supply current (typically 100 uA per floating input) and may trigger false interrupts. Also note that pins shared with ADC inputs should be configured as analog (ANSELx set) when used as analog, or digital noise will couple into the ADC readings. Estimated: typical ADC SNR degradation from unconfigured digital inputs is 4-6 dB.

For ADC accuracy, place a small RC filter (10 ohm + 100 nF) on each analog input pin near the MCU to attenuate transient spikes from digital switching. Route analog signals with ground guard traces on both sides, and keep analog traces away from switching nodes like PWM outputs or oscillator traces. Avoid running analog traces parallel to high-current traces; if you must cross, do so at 90 degrees. These layout practices will preserve the 10-bit ADC linearity at full throughput.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant and lead-free per Microchip product environmental compliance documentation. Not AEC-Q100 qualified - use PIC18FxxK80 family for automotive safety applications. REACH compliance status published in Microchip material declaration database.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC18F4320 PIC18F4320-E/ML PIC18F4520-E/ML PIC18F4220-E/ML PIC18F4320-I/ML PIC18F4420-I/ML PIC18F family PIC microcontroller 8-bit MCU Flash memory EEPROM SRAM QFN package surface mount RoHS REACH AEC-Q100 extended industrial temperature 10-bit ADC MSSP SPI I2C AUSART CCP PWM
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