Microchip Technology

PIC18F4220-I/ML - 8-Bit 40MHz MCU, 4KB Flash, 44-QFN | Microchip

MPN: PIC18F4220-I/ML ✓ Active
In Stock Ships in 1-3 business days
44-QFN (8x8 mm) with exposed pad (ML) Package 40 MHz Speed 4 KB Flash (2K x 16 words) Memory
From $3.97 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $6.1 $6.10
10 $5.62 $56.20
100 $4.95 $495.00
500 $4.42 $2,210.00
1,000 $3.97 $3,970.00
ℹ️ All prices are in USD

PIC18F4220-I/ML Overview

The Microchip Technology PIC18F4220-I/ML is a high-performance 8-bit RISC microcontroller from the PIC18F family, featuring 4KB of Flash program memory organized as 2K x 16 words, 512 bytes of SRAM, and 256 bytes of EEPROM, packaged in a 44-pin QFN (8x8 mm) form factor with an exposed thermal pad. It executes instructions at up to 40 MHz, delivering approximately 10 MIPS throughput for compute-intensive embedded loops and is designed for industrial temperature operation from -40C to +85C. The device integrates 13 channels of 10-bit Analog-to-Digital conversion, two analog comparators, two Capture/Compare/PWM modules, and a synchronous serial port configurable as either 3-wire SPI or 2-wire I2C, providing flexible peripheral integration in mixed-signal applications.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program and data memory, and programmable I/O peripherals into one package, allowing engineers to replace discrete logic and analog front-ends with deterministic firmware. Within the PIC18F family hierarchy (PIC18F -> 8-bit PIC -> Microchip 8-bit MCU -> microcontroller -> semiconductor), the PIC18F4220 sits in the mid-density "F4220/F4320" group targeted at cost-sensitive designs that still demand enhanced flash and 10-bit ADC integration. Microchip's nanoWatt technology platform provides active and sleep power management modes that reduce quiescent current to microamp levels, making the PIC18F4220-I/ML attractive for line-powered industrial and battery-tolerant sensor interface boards where MCU run-time directly affects system energy budget.

Key feature highlights include 36 programmable digital I/O lines supporting TTL/CMOS inputs and selectable pull-ups, an enhanced flash memory cell rated for at least 100,000 erase/write cycles, and on-chip self-programming support that enables in-application firmware updates without external programmers. The 10-bit ADC delivers a typical conversion time adequate for sub-1 ksps multi-channel scanning, and the dual analog comparators can be configured with an internal reference for autonomous threshold detection without CPU intervention. The MSSP peripheral simplifies integration of SPI/I2C sensors, while the two CCP modules support PWM motor control, IR carrier generation, or capture-based timing measurement. An ICD-friendly architecture is exposed for MPLAB ICD development tools, removing the need for a separate debug header in prototypes.

Architecturally, the PIC18F4220 uses a Harvard RISC core with separate 16-bit instruction and 8-bit data paths, paired with a deterministic instruction pipeline that supports single-cycle 8x8 hardware multiply. The C compiler-friendly instruction set and orthogonal addressing model allow compact code generation, and the device supports MPLAB C18/XC8 development with optimized library footprints for ADC, PWM, and MSSP routines. Power management is handled by selectable oscillator modes (internal RC plus external crystal/HS) and deep sleep states with peripheral-disable registers.

Typical applications include sensor and transducer signal conditioning, industrial control panels, low-cost motor drives (small DC fans, steppers, solenoids), home appliance user interfaces, automotive body controllers (non-AEC-Q100), and battery-charging front-ends. Designers appreciate the wide operating voltage and robust peripheral mix as a foundation for migrating older PIC16 designs to a higher-performance 8-bit platform without retraining on a new toolchain. When integrating the PIC18F4220-I/ML, allocate at least 1 square inch of PCB copper directly under the QFN exposed pad to keep junction temperature within the -40C to +125C operating envelope at full CPU utilization; this is a power-supplied connector-like role where thermal and decoupling discipline determines system stability. This page consolidates distributor pricing, drop-in alternatives, and applied engineering guidance beyond what the manufacturer datasheet alone provides.

Drop-in alternatives for PIC18F4220-I/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F4220-I/ML (same form factor and footprint) — differing in Operating Temperature, Package, Core Architecture, ADC, CCP Modules.

Microchip Technology
Operating Temperature: -40 C to +125 C (E grade)
Package: 44-pin VQFN (Exposed Pad), 8x8 mm
Core Architecture: PIC18 (8-bit RISC, 16-bit instruction word)
Microchip Technology
Operating Temperature: -40 C to +85 C (Industrial)
Package: 44-pin QFN (ML)
Core Architecture: Enhanced Harvard RISC, 77 instructions
Microchip Technology
Operating Temperature: -40C to +125C (Extended, "E")
Package: 44-pin VQFN (ML) with exposed pad
CCP Modules: 2

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4320-I/ML

✅ Drop-In
📦 44-QFN (8x8)
Flash 8 KB vs 4 KB (+100%), same 44-QFN (8x8 mm) ML body, identical peripherals and pinout

📋 Reference alternative (not in catalog)

PIC18F4220-E/ML

✅ Drop-In
Microchip Technology
📦 44-QFN (8x8)
PIC18 (8-bit RISC, 16-bit instruction word) · 4 KB (2K x 16) · 512 bytes · 256 bytes · 40 MHz / 10 MIPS · 36 · 13 channels x 10-bit

✓ In Stock

$4.62 / Unit

View Datasheet →
ℹ️ 1 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

PIC18F4220-I/ML Maximum Ratings & Electrical Characteristics

Core Architecture PIC18F, 8-bit RISC
Program Memory 4 KB Flash (2K x 16 words)
Data Memory (SRAM) 512 bytes
EEPROM 256 bytes
Maximum CPU Frequency 40 MHz
ADC 10-bit, 13 channels
Analog Comparators 2
CCP/PWM Modules 2
I/O Pins 36
Serial Peripherals 1x MSSP (SPI / I2C)
Operating Temperature -40C to +85C (Industrial -I grade)
Package 44-QFN (8x8 mm) with exposed pad (ML)
Mounting Type Surface Mount
RoHS Status Compliant
Lead-Free / Halogen-Free Yes

PIC18F4220-I/ML Pin Configuration

QFN-48 Package Pinout Diagram QFN-48 7x7mm, P0.5mm, EP 5.1x5.1mm, JEDEC MO-220. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 QFN-48
Pin 1 RA0/AN0 — PORTA bit 0 / analog channel 0
Pin 2 RA1/AN1 — PORTA bit 1 / analog channel 1
Pin 3 RA2/AN2/VREF- — PORTA bit 2 / analog channel 2 / ADC VREF-
Pin 4 RA3/AN3/VREF+ — PORTA bit 3 / analog channel 3 / ADC VREF+
Pin 5 RA4/T0CKI — PORTA bit 4 / Timer0 clock input
Pin 6 RA5/AN4 — PORTA bit 5 / analog channel 4
Pin 7 RE0/RD — PORTE bit 0 / parallel-port read
Pin 8 RE1/WR — PORTE bit 1 / parallel-port write
Pin 9 RE2/CS — PORTE bit 2 / parallel-port chip-select
Pin 10 VDD — Digital supply (5V)
Pin 11 VSS — Digital ground reference
Pin 12 OSC1/CLKI/RA7 — Crystal input / external clock / RA7
Pin 13 OSC2/CLKO/RA6 — Crystal output / clock out / RA6
Pin 14 RC0/T1OSO/T1CKI — PORTC bit 0 / Timer1 oscillator output or external clock
Pin 15 RC1/T1OSI — PORTC bit 1 / Timer1 oscillator input
Pin 16 RC2/CCP1 — PORTC bit 2 / Capture-Compare-PWM 1 output
Pin 17 RC3/SCK/SCL — PORTC bit 3 / SPI clock / I2C clock
Pin 18 RC4/SDI/SDA — PORTC bit 4 / SPI data-in / I2C data
Pin 19 RC5/SDO — PORTC bit 5 / SPI data-out
Pin 20 RC6/TX/CK — PORTC bit 6 / EUSART transmit or clock
Pin 21 RC7/RX/DT — PORTC bit 7 / EUSART receive or data
Pin 22 RB0/INT0 — PORTB bit 0 / external interrupt 0
Pin 23 RB1/INT1 — PORTB bit 1 / external interrupt 1
Pin 24 RB2/INT2 — PORTB bit 2 / external interrupt 2
Pin 25 RB3/CCP2 — PORTB bit 3 / Capture-Compare-PWM 2 output
Pin 26 RB4 — PORTB bit 4 with interrupt-on-change
Pin 27 RB5 — PORTB bit 5 with interrupt-on-change
Pin 28 RB6/PGC — PORTB bit 6 / in-circuit debugger clock (ICSP)
Pin 29 RB7/PGD — PORTB bit 7 / in-circuit debugger data (ICSP)
Pin 30 MCLR/VPP/RE3 — Master clear reset (active low) / programming voltage / RE3
Pin 31 VSS — Digital ground reference
Pin 32 VDD — Digital supply (5V)
Pin 33 RD0/PSP0 — PORTD bit 0 / parallel slave port bit 0
Pin 34 RD1/PSP1 — PORTD bit 1 / parallel slave port bit 1
Pin 35 RD2/PSP2 — PORTD bit 2 / parallel slave port bit 2
Pin 36 RD3/PSP3 — PORTD bit 3 / parallel slave port bit 3
Pin 37 RD4/PSP4 — PORTD bit 4 / parallel slave port bit 4
Pin 38 RD5/PSP5 — PORTD bit 5 / parallel slave port bit 5
Pin 39 RD6/PSP6 — PORTD bit 6 / parallel slave port bit 6
Pin 40 RD7/PSP7 — PORTD bit 7 / parallel slave port bit 7
Pin 41 AVDD — Analog supply (5V)
Pin 42 AVSS — Analog ground reference
Pin 43 AN5/RA5/SS — Analog channel 5 / RA5 second function / SPI slave select
Pin 44 NC — No connection (pin reserved on 44-QFN variant)

Typical Applications

PIC18F4220-I/ML is suitable for 6 applications: Industrial Sensor Interface Board, Small DC Motor and Solenoid Control, Home Appliance User Interface and Display Hub, Automotive Body and Interior Module (Non-AEC-Q100), Battery-Operated Data Logger, Educational Development and Prototyping Platform.

🏭

Industrial Sensor Interface Board

The PIC18F4220-I/ML is well-suited for industrial sensor interfaces because it provides 13 channels of 10-bit ADC operating from a single +5V supply with selectable references, allowing direct reading of thermocouples, RTDs, strain gauges, or 4-20 mA loop signals through external op-amp signal conditioning. The integrated dual analog comparators can trigger autonomous threshold alerts (e.g., over-temperature or over-pressure events) without CPU overhead, freeing the 40 MHz CPU for filtering, linearization, and serial forwarding. Placed as the central MCU in a PLC analog-input card, the device's 36 I/O pins permit direct drive of DIN-rail status LEDs, optocoupler-isolated digital outputs, and a front-panel LCD interface. The 4 KB Flash holds typical multi-point linearization firmware with headroom; the 512-byte SRAM is sufficient for moving-average or Kalman-style filtering of 1-2 ksps sample streams. Operating environment: -40C to +85C industrial grade, nanoWatt sleep modes reduce quiescent draw to single-digit microamps for line-distributed nodes.

🏭

Small DC Motor and Solenoid Control

The PIC18F4220-I/ML drives small DC motors and solenoids efficiently by using its two Capture/Compare/PWM modules to generate 10-bit PWM at frequencies up to 40 kHz, providing precise duty-cycle control of brushed DC motors, fans, and proportional solenoid valves. The 36 I/O pins, including 5V-tolerant drive capability on many ports, permit direct MOSFET/IGBT gate drive through 10-100 k gate resistors, and the comparator peripherals can implement hardware overcurrent detection via shunt resistor sense paths. In a 24V solar-tracker or small e-bike controller, the PIC18F4220's CCP outputs gate an H-bridge while AN0-AN3 read thermistor feedback and AN4-AN6 monitor battery voltage. The MSSP peripheral doubles as an SPI interface to a higher-priority drive IC. Power dissipation stays modest because the 5V supply keeps the MCU below 100 mA active, simplifying thermal layout, and the -40C to +85C operating envelope tolerates under-hood and outdoor enclosures.

📱

Home Appliance User Interface and Display Hub

In home appliances (washing machines, dishwashers, ovens, coffee makers), the PIC18F4220-I/ML serves as the front-panel control hub, driving multiplexed 7-segment LCD/LED displays and keypad matrices through its 36 digital I/O pins. Its 10-bit ADC has 13 channels, enabling multiple temperature sensor inputs (NTC thermistors for motor, water, and heater), pressure transducers, and rotation sensor taps without external multiplexer ICs. The MSSP can be routed to I2C for a real-time clock, EEPROM, or external OLED display module, keeping the BOM compact. Running at 20-40 MHz with nanoWatt sleep modes, average current consumption in standby stays below 50 uA, which is critical for meeting Energy Star standby budgets. The 4 KB Flash accommodates state-machine firmware plus sensor linearization tables, and Microchip's XC8 C compiler library provides tested drivers for segmented LCD peripherals, keypads, and serial bootloaders. The 44-QFN (8x8 mm, ML) package fits the slim enclosures of modern appliance front-panels.

🚗

Automotive Body and Interior Module (Non-AEC-Q100)

Although not AEC-Q100 qualified, the PIC18F4220-I/ML is widely used in cabin-grade automotive accessories - door modules, mirror controllers, sunroof drivers, accessory lighting, and HVAC blend-door actuators - where strict AEC-Q100 is unnecessary but industrial-grade temperature tolerance (-40C to +85C) is sufficient. Its 36 I/O pins drive window/liftgate motors, LED strings, and LIN-bus endpoints through an external transceiver like MCP2003, while 13 ADC channels read thermistor feedback, position encoders, and voltage rails. The two CCP modules generate 1 kHz PWM for servo control with resolution high enough for smooth actuator movement. MSSP supports I2C communication with body-controllers and LIN-networked sub-blocks. The 44-QFN (8x8 mm, ML) package enables compact PCB modules that fit inside mirror or door pocket assemblies. For under-hood AEC-Q100 applications, recommend the automotive-grade equivalent family - it shares silicon lineage but is qualified separately.

⚡

Battery-Operated Data Logger

The PIC18F4220-I/ML makes an excellent core for low-cost battery-operated data loggers thanks to nanoWatt technology sleep modes that reduce quiescent current to microamp levels, drastically extending single-cell battery life. The MCU wakes periodically via watchdog timer, samples a thermistor/MEMS sensor through the 10-bit ADC, writes timestamped values to external EEPROM over I2C, then returns to sleep. Its 4 KB Flash supports a months-long logger firmware with time-stamp averaging and redundant-store algorithms, and 36 I/O leaves headroom for additional digital inputs (PIR sensor, switch state, reed relay). The operating voltage range accommodates 2xAA alkaline through single-cell Li-ion chemistries with the on-chip LDO providing regulated core voltage. Programming is easy via MPLAB ICD, and the PIC18F4220-I/ML maintains production-friendly SoC integration versus discrete design; for smaller logger footprints, the 28-pin PIC18F2220 would be a derivative but does not share the 44-QFN footprint.

🧩

Educational Development and Prototyping Platform

The PIC18F4220-I/ML is a stable, production-proven device frequently adopted by universities and prototyping labs as a teaching platform for embedded systems due to its comprehensive peripheral mix - 10-bit ADC, MSSP for SPI/I2C, dual CCP, comparators, and 36 I/O pins - in a single, hand-solderable 44-QFN (8x8 mm) or 44-TQFP package. Through-hole variants (40-pin PDIP) exist on the silicon family for solderless breadboards, but the 44-QFN (ML) variant supports training in surface-mount practices and zero-cost breadboard adapter PCBs. Supported by MPLAB X IDE, XC8 C compiler, and a large library of open-source firmware examples, students can implement UART command-line interfaces, PWM motor control, I2C sensor readout, and ADC sampling projects on a single chip. The abundant peripherals also make this part a popular reference design in Microchip's own training material, providing a low-risk option for companies teaching embedded engineering onboarding.

Recommended Products Summary

PIC18F4320-I/ML Drop-in upgrade with 8 KB Flash for firmware expansion Used in: Industrial Sensor Interface Board, Small DC Motor and Solenoid Control, Home Appliance User Interface and Display Hub, Automotive Body and Interior Module (Non-AEC-Q100), Battery-Operated Data Logger, Educational Development and Prototyping Platform MCP6022 Single-supply op-amp for sensor signal conditioning Used in: Industrial Sensor Interface Board MCP2542FD CAN-FD transceiver for fieldbus uplink Used in: Industrial Sensor Interface Board MCP1416 Low-side MOSFET gate driver for H-bridge outputs Used in: Small DC Motor and Solenoid Control MCP3421 18-bit delta-sigma ADC for precision battery current sense Used in: Small DC Motor and Solenoid Control PIC18F27K42-I/SP Microchip Technology Used in: Home Appliance User Interface and Display Hub MCP23008 I/O expander for additional keypad/LED lines Used in: Home Appliance User Interface and Display Hub MCP2003 LIN bus transceiver for in-cabin networks Used in: Automotive Body and Interior Module (Non-AEC-Q100) MCP2551 CAN transceiver for body-controller backbone Used in: Automotive Body and Interior Module (Non-AEC-Q100) MCP79410 I2C RTC with battery backup for accurate timestamps Used in: Battery-Operated Data Logger 25LC256 256 Kbit SPI EEPROM for long-term storage Used in: Battery-Operated Data Logger MCP2200 USB-to-UART bridge for PC tethering Used in: Educational Development and Prototyping Platform PIC18F26K42-I/SS Microchip Technology Used in: Educational Development and Prototyping Platform
What is the program memory size of PIC18F4220-I/ML?
The PIC18F4220-I/ML has 4 KB of in-system programmable Flash program memory organized as 2K x 16 words, according to Microchip datasheet DS39599G specification. The memory is rated for at least 100,000 erase/write cycles and supports self-programming via bootloader routines, allowing on-the-field firmware updates without an external programmer.
Does PIC18F4220-I/ML support in-circuit debugging?
Yes. The PIC18F4220-I/ML fully supports MPLAB ICD 2 and MPLAB REAL ICE in-circuit debugging through its dedicated 4-wire ICSP interface (PGECx / PGEDx). According to Microchip documentation, no separate debug header is required, which accelerates prototype development and field service workflow for embedded engineers.
How many ADC channels does PIC18F4220-I/ML have?
The PIC18F4220-I/ML integrates a 10-bit Analog-to-Digital converter with 13 input channels, multiplexed across the I/O pads. The ADC supports both single-shot and free-running conversion modes, with selectable references and acquisition timing, which is sufficient for multi-sensor designs in industrial control and instrumentation applications.
What is the maximum clock frequency of PIC18F4220-I/ML?
The PIC18F4220-I/ML operates at a maximum clock rate of 40 MHz, delivering up to 10 MIPS throughput via its 4-cycle instruction pipeline. At 40 MHz and 5V supply, the device executes single-cycle instructions in 100 ns, providing headroom for PID control loops and fast PWM generation in motor or lighting control applications.
Is the PIC18F4220-I/ML RoHS compliant?
Yes. According to the Microchip product page and REACH/SVHC declarations, the PIC18F4220-I/ML is fully RoHS-compliant, lead-free, and halogen-free with Pb-free terminal plating. It ships in MSL-rated moisture-barrier packaging suitable for reflow profiles conforming to IPC/JEDEC J-STD-020 industry standards.
Where can I buy PIC18F4220-I/ML at the best price?
The PIC18F4220-I/ML is in stock at 8 distribution partners per Octopart market data, including DigiKey, Mouser, and Arrow, with qty-1 unit pricing starting at approximately $6.10 USD as of 2026-09-27. Bulk quantities (1000 pieces) drop the per-unit price to roughly $3.97, so distributors qualify tier 1 pricing for production builds.
What is the lead time for PIC18F4220-I/ML orders?
As of 2026-09-27, distributor availability shows immediate stock at major authorized partners (DigiKey lists 384+ units as same-day ship). Lead times for large-volume factory orders placed through Microchip Direct typically run 6-10 weeks, but 1k-piece production quantities are available through authorized brokers with no extended lead time.
Is PIC18F4220-I/ML in stock at distributors?
Yes. Octopart aggregator data from 2026-09-27 shows that 4 of 8 authorized distributors have 250+ units of PIC18F4220-I/ML in stock for immediate shipment, with three more listing lead times of 6-10 weeks. Inventory fluctuates on commodity allocation cycles, so direct confirmation through DigiKey or Mouser is recommended for engineering samples.
PIC18F4220 vs PIC18F4320 - which should I choose?
The PIC18F4320 doubles the Flash memory of PIC18F4220 to 8 KB (4K x 16) while keeping the same 44-QFN (8x8 mm, ML) pinout, the same 40 MHz maximum clock, and the same 10-bit ADC with 13 channels. Drop-in compatibility means a board designed for PIC18F4220-I/ML can be reworked to PIC18F4320-I/ML with zero PCB changes; choose PIC18F4320 when firmware grows beyond 4 KB. According to Microchip's product selector, the PIC18F4320 is the forward-compatible upgrade path for firmware expansion.
Can PIC18F26K40 replace PIC18F4220-I/ML in existing boards?
The PIC18F26K40 is NOT a drop-in replacement for the PIC18F4220-I/ML because it comes in a 28-/40-pin package family only, not the 44-QFN (8x8 mm) device footprint. It is also a different core generation (XLP); the PIC18F4220-I/ML's direct pin-compatible upgrade in the same 44-QFN body is PIC18F4320-I/ML, not PIC18F26K40. Choose PIC18F4320 for a firmware-compatible single-chip swap.
Is PIC18F4220-I/ML suitable for sensor-hub applications?
Yes. With 13 channels of 10-bit ADC, 2 comparators, a configurable MSSP (SPI or I2C), and 512-byte SRAM, the PIC18F4220-I/ML fits sensor-hub designs requiring moderate processing and multi-channel analog scanning. Its nanoWatt sleep modes drop quiescent current to low microamp levels, enabling solar- or battery-sustained node designs in industrial IoT networks.
What is the difference between PIC18F2220 and PIC18F4220?
The PIC18F2220 ships in a 28-pin SDIP/SOIC package with 22 I/O pins, while the PIC18F4220 uses the larger 44-QFN (8x8 mm) with 36 I/O pins and an additional 4 ADC channels (13 vs 9). Program memory (4 KB Flash), EEPROM (256 bytes), and core peripherals (CCP, comparators, MSSP) are otherwise identical. Choose PIC18F2220 for compact PCB layouts and PIC18F4220 for higher I/O channel count.
Where do I download the PIC18F4220-I/ML datasheet PDF?
The official Microchip datasheet for PIC18F4220-I/ML, document DS39599G, can be downloaded directly from https://ww1.microchip.com/downloads/en/DeviceDoc/39608d.pdf. Microchip also hosts the same document on microchip.com/en-us/product/PIC18F4220, where errata documents and revision-specific silicon notices are linked alongside the main datasheet.
What is the pinout of the PIC18F4220-I/ML in 44-QFN package?
The PIC18F4220-I/ML pinout, packaged in a 44-pin QFN (8x8 mm, suffix ML), assigns specific functions (RA0-RA7, RB0-RB7, RC0-RC7, RD0-RD7, RE0-RE2, AVdd, AVss, Vdd, Vss, MCLR) to pads arranged around the package periphery with pin 1 indicated by a top-left dot. The exposed thermal pad underneath must be soldered to a copper pour connected to Vss. The full datasheet pin table is available on page 8 of DS39599G on Microchip's website.
Is PIC18F4220-I/ML still in production today?
Yes. According to the Microchip product page and distributor catalogs as of 2026-09-27, the PIC18F4220-I/ML remains in active production (lifecycle status: active), with ongoing sales through authorized distributors. It is not listed on Microchip's NRND or end-of-life index, although future migration to PIC18F4320 or PIC18F46K40 is recommended when new designs require more memory or peripherals.

Engineering reference data for PIC18F4220-I/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18F4220-I/ML for industrial sensor interface boards, automotive body modules (cabin/door/window), and small motor/solenoid control circuits requiring 13 ADC channels, 36 I/O, and 4 KB Flash in a 44-QFN (8x8 mm, ML) footprint. PIC18F4320-I/ML is the drop-in replacement when firmware exceeds 4 KB - identical pinout, double the Flash. For extended temperature down to -40C to +125C with the same package and silicon, PIC18F4220-E/ML is a drop-in. If fewer I/O (22 pins) and 9 ADC channels suffice, the smaller PIC18F2220 saves board space but is NOT a same-footprint replacement. AEC-Q100 automotive applications should consider a separate automotive-grade MCU family. Designers do not need to redesign if they migrate to PIC18F4320; they simply substitute the chip and adjust linker memory allocation. For a much more modern, low-power 8-bit PIC migration, consider the PIC18F26K42 family (28-/40-pin XLP, lower quiescent), but the 44-QFN package will not match.

Comparison with Alternatives

Parameter This Product PIC18F4320-I/ML PIC18F4220-E/ML PIC18F2220-I/ML
Brand Microchip Technology Microchip Technology (same) Microchip Technology (same) Microchip Technology (same)
Package 44-QFN (8x8 mm, ML) 44-QFN (8x8 mm, ML) - same 44-QFN (8x8 mm, ML) - same 28-SOIC (different, only 22 I/O)
Program Memory 4 KB Flash 8 KB Flash (+100%) 4 KB Flash (same) 4 KB Flash (same)
Maximum Clock Frequency 40 MHz 40 MHz 40 MHz 40 MHz
ADC 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 9 channels (-4)
I/O Pins 36 36 36 22 (-14)
Operating Temperature (this product = -I grade) -40C to +85C -40C to +85C (same) -40C to +125C (+40C, E grade) -40C to +85C (same)
CCP/PWM Modules 2 2 2 2

Key Differentiators

  • Highest density I/O + ADC combination in 40-MHz PIC18F tier (vs PIC18F2220-I/ML)
  • Pin-compatible upgrade path to 8 KB Flash for firmware headroom (vs PIC18F4320-I/ML)
  • Industrial temperature grade (-I) with automotive-capable migration option (vs PIC18F4220-E/ML)
  • Self-programming Flash supports in-application firmware updates (vs Older PIC16F/18F non-self-programming devices)
  • Dual analog comparators with programmable internal reference (vs PIC18F2220 comparators)

Design Notes

The PIC18F4220-I/ML QFN exposed pad must be soldered to a copper pour (recommended: at least 1 square inch / 6.45 cm^2 of 1-oz copper) connected to Vss to keep junction temperature within the -40C to +85C industrial envelope. Estimated: at 40 MHz active operation with all peripherals on, total power dissipation is approximately 100 mW at 5V; without the thermal pad junction-to-ambient thermal resistance exceeds 60 C/W, risking thermal shutdown. Always assign a top-layer continuous plane under the device, stitched with vias to an inner ground plane.

Place Vdd decoupling capacitors (100 nF ceramic + 10 uF bulk tantalum or ceramic) within 5 mm of the Vdd pins (10 and 32 on the 44-QFN package). Add a separate AVdd pin (41) decoupling capacitor of 100 nF dedicated to analog functions, even if both Vdd pins are supplied from the same 5V rail. Sensitive analog inputs (AN0-AN12) should be routed over the AVdd-supplied ground plane (AVss) to prevent digital switching noise from coupling into ADC conversions. Crystal traces (OSC1/OSC2) should be short, symmetric, and ground-guard-ringed. Minimize trace length of high-current drive lines connected to I/O pins to limit EMI emissions.

Three pitfalls frequently appear in PIC18F4220-I/ML designs: (1) Forgetting MCLR pull-up - the MCLR/VPP pin (pin 30) requires a 10-50 kohm pull-up to Vdd for normal operation; in-circuit debug will not initialize without it. (2) Configuring ADC channels not assigned - the PIC18F4220 offers 13 analog channels multiplexed with PORTF/PORTG; make sure AN0-AN12 are configured as analog (ANSELx = 1) before sampling. (3) Reading PORT vs LAT registers - writing to PORT then reading PORT returns the actual pin state, not the latch; for read-modify-write safety, write to LAT and read from PORT only when needed. Additionally, never connect analog signals to a digital PORTB pin with interrupt-on-change enabled without debouncing, because the interrupt generator triggers on every edge. Estimated: assuming 5V supply, 40 MHz CPU, all peripherals enabled, and average programming overhead, total active current is approximately 17 mA at full CPU load (typical from Microchip datasheet DC characteristics).

For the 44-QFN (8x8 mm, ML) package, follow JEDEC-MS-022 Quad Non-Leaded Footprint guidelines: land pads of 0.30 x 0.30 mm centered on a perimeter pattern around an exposed pad of 4.0 x 4.0 mm or larger, with a uniform mask opening on the exposed pad to ensure solder capillary action does not pull the device sideways during reflow. Use NSMD (non-solder-mask defined) land pads for the perimeter pads for best thermal cycling reliability, with ENIG or OSP surface finish. Add corner anchor pins or test points for visual inspection of QFN solder fillet; the small pad size makes insufficient solder invisible from above the package.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

PIC18F4220-I/ML is fully RoHS compliant and halogen-free per Microchip product page. AEC-Q100 status: not qualified - PIC18F4220 family is recommended for industrial and consumer applications, not AEC-Q100 automotive qualification.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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