Microchip Technology

PIC32MX350F256L-V/PT - 80MHz 256KB Flash 32-bit MCU | Microchip

MPN: PIC32MX350F256L-V/PT ✓ Active
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2.3 V to 3.6 V Vdss 100-pin TQFP (PT) 12x12 mm Package 80 MHz Speed 256 KB Memory
From $5.45 USD / Unit
MOQ: 1 |
Price updated: 2026-10-02
Volume Pricing
Qty Unit Price Extended
1 $8.62 $8.62
10 $7.71 $77.10
100 $6.89 $689.00
500 $6.12 $3,060.00
1,000 $5.45 $5,450.00
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PIC32MX350F256L-V/PT Overview

The Microchip Technology PIC32MX350F256L-V/PT is a 32-bit RISC microcontroller based on the MIPS32 M4K core, delivering 80 MHz of core clock and 256 KB of FLASH program memory with 64 KB of SRAM, packaged in a 100-pin TQFP (PT) footprint. It integrates two analog comparators, two I2C, two SPI/I2S peripherals, and 28 ADC channels, targeting audio/graphics/touch (HMI), USB, and advanced analog applications.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program and data memory, and programmable I/O peripherals into one package. The PIC32MX350 family occupies the mid-range of Microchip's 32-bit PIC32 portfolio, positioned between the smaller PIC32MX1/2/3xx series and the higher-pin PIC32MX5/6/7xx families. Its MIPS32 M4K core executes the MIPS instruction set, distinguishing it from Cortex-M based MCUs and making it a natural choice for designs migrating from older PIC24/PIC32 platforms.

Key differentiating features include a USB 2.0 full-speed device/host/OTG controller, a 16-channel 10-bit ADC with up to 1 Msps conversion rate, and CTMU/PTG support for capacitive touch sensing. The device also exposes up to 85 I/O pins with peripheral pin select, supports up to four UART modules, and integrates a charge time measurement unit for touch and proximity applications. The -V temperature grade spans -40C to +105C, making it suitable for industrial environments.

Typical applications include USB audio interfaces, capacitive touch HMI panels, sensor hubs, and industrial control modules. The combination of DSP extensions, large RAM, and integrated USB simplifies designs that previously required an external MCU plus a USB bridge IC.

When designing with this device, budget for an external 8 MHz crystal to drive the PLL up to 80 MHz; PIC32MX devices do not include an internal 80 MHz oscillator on this family. Decouple VDD with at least four 100 nF ceramic capacitors placed close to the four VDD/VSS pin pairs to keep core and I/O noise within spec.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for PIC32MX350F256L-V/PT — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32MX350F256L-V/PT (same form factor and footprint) — differing in Package, Operating Temperature, ADC, Program Memory (Flash), DMA Channels.

Microchip Technology
Package: 100-pin TQFP (12x12 mm)
Operating Temperature: -40C to +105C (V grade)
Program Memory (Flash): 512 KB (512K x 8)
Microchip Technology
Package: 64-pin TQFP (10x10x1 mm)
Operating Temperature: -40C to +105C (-80V grade)
ADC: 10-bit, 1 Msps
Microchip Technology
ADC: 10-bit, up to 28 channels
Microchip Technology
Package: 100-pin TQFP (PT), 12 x 12 mm
ADC: 10-bit, up to 28 channels, 1 Msps
Program Memory (Flash): 256 KB (plus 12 KB auxiliary)
Microchip Technology
Package: 124-pin VTLA (9x9 mm) with Exposed Pad
ADC: 10-bit, up to 28 channels
Program Memory (Flash): 256 KB (256K x 8)
Microchip Technology
Operating Temperature: -40C to +105C (V-grade)
ADC: 10-bit, 1 MSPS, 16 channels
Program Memory (Flash): 256 KB (256K x 8)
Microchip Technology
Package: 121-TFBGA (10x10 mm)
Operating Temperature: -40C to +85C (Industrial)
ADC: 10-bit, up to 16 channels, 1 Msps
Microchip Technology
Operating Temperature: -40C to +105C (V grade)
ADC: 10-bit, up to 28 channels
Program Memory (Flash): 512 KB (512K x 8)
Microchip Technology
Package: 100-pin TQFP (PT) 12x12 mm, 0.4 mm pitch
ADC: 10-bit, up to 28 channels
Program Memory (Flash): 128 KB
Microchip Technology
Package: 100-pin TQFP (PT), 12x12 mm
Operating Temperature: -40C to +105C
Microchip Technology
Package: 124-VTLA (9x9 mm) with exposed pad
Operating Temperature: -40 C to +105 C (industrial)
ADC: 10-bit, 1 Msps, up to 28 channels
Microchip Technology
Package: 100-pin TQFP (PT), 12x12 mm

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32MX350F256LT-V/PT

✅ Drop-In
📦 TQFP-100 (PT)
tape-and-reel packing variant; same die, same TQFP-100 footprint

📋 Reference alternative (not in catalog)

PIC32MX350F256L-I/PT

✅ Drop-In
Microchip Technology
📦 TQFP-100 (PT)
MIPS32 M4K (32-bit RISC) · 120 MHz (150 DMIPS) · 80 MHz · 256 KB (plus 12 KB auxiliary) · 64 KB · 2.3 V to 3.6 V · -40 C to +105 C (industrial, I suffix) · 100-pin TQFP (PT), 12 x 12 mm

✓ In Stock

$4.31 / Unit

View Datasheet →

PIC32MX350F128L-V/PT

✅ Drop-In
Microchip Technology
📦 TQFP-100 (PT)
MIPS32 M4K · 32-bit · 32 bit · 80 MHz · 128 KB (128K x 8) Flash · 32 KB · 85 · 2.3 V to 3.6 V

✓ In Stock

$2.99 / Unit

View Datasheet →

PIC32MX340F256H-80V/PT

✅ Drop-In
Microchip Technology
📦 TQFP-100 (PT)
MIPS32 M4K · 32-bit · 256 KB (256K x 8) · 32 KB (32K x 8) · 80 MHz · 2.3 V to 3.6 V · 53 · 10-bit, 1 Msps

✓ In Stock

$4.4 / Unit

View Datasheet →

PIC32MX270F512L-V/PT

✅ Drop-In
Microchip Technology
📦 TQFP-100 (PT)
MIPS32 M4K · 32-bit · 50 MHz · 83 DMIPS · 512 KB (512K x 8) · 64 KB · 2.3 V to 3.6 V · -40C to +105C (V grade)

✓ In Stock

$6.48 / Unit

View Datasheet →

PIC32MX350F256L-V/PT Maximum Ratings & Electrical Characteristics

Core Architecture MIPS32 M4K (32-bit RISC)
Maximum CPU Clock 80 MHz
DMIPS Performance 120 DMIPS
Program Memory (Flash) 256 KB
Data Memory (SRAM) 64 KB
Operating Voltage 2.3 V to 3.6 V
I/O Pins 85 (maximum)
ADC Channels 28
ADC Resolution 10-bit, 1 Msps
Analog Comparators 2
I2C Modules 2
SPI / I2S Modules 2
UART Modules 4
USB Controller USB 2.0 full-speed device/host/OTG
Operating Temperature -40C to +105C (-V grade)
Package 100-pin TQFP (PT) 12x12 mm
Mounting Type Surface Mount
RoHS Status Compliant

PIC32MX350F256L-V/PT 100-pin tqfp (pt) 12x12 mm Pin Configuration Guide

Pin configuration for PIC32MX350F256L-V/PT (100-pin tqfp (pt) 12x12 mm package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

100-pin tqfp (pt) 12x12 mm package pinout diagram for PIC32MX350F256L-V/PT

No detailed pinout data available for PIC32MX350F256L-V/PT.

Refer to the datasheet for full pin configuration.

Typical Applications

PIC32MX350F256L-V/PT is suitable for 6 applications: USB Audio Interface, Capacitive Touch HMI Panel, Industrial Sensor Hub, USB Barcode / Scanner Interface, Medical Data Logger, Smart Home Gateway Node.

🎧

USB Audio Interface

The PIC32MX350F256L-V/PT's integrated USB 2.0 full-speed OTG controller, dual I2S peripherals, and 64 KB of SRAM make it a strong fit for USB Audio Class 1.1 streaming applications at 48 kHz / 24-bit. The 100-pin TQFP package exposes both I2S data lines and USB DP/DM directly, eliminating an external USB PHY. Compared to a discrete MCU-plus-USB-bridge design, the single-chip integration reduces BOM cost by roughly 30% and PCB area by 40%. Latency measured in similar designs is typically under 10 ms round-trip.

📱

Capacitive Touch HMI Panel

The on-chip CTMU hardware combined with the 28-channel 10-bit ADC enables robust capacitive touch sensing on the PIC32MX350F256L-V/PT. Designers can drive up to 28 touch electrodes directly without an external touch controller, supporting HMI panels up to 7 inches diagonal. The 64 KB SRAM is sufficient to run Microchip's mTouch library plus an LVGL UI stack. Operating temperature of -40C to +105C supports indoor industrial panels. Power consumption during idle touch scanning is approximately 8 mA at 80 MHz core.

🏭

Industrial Sensor Hub

With 4 UART, 2 SPI, and 2 I2C interfaces plus a 10-bit 1 Msps ADC, the PIC32MX350F256L-V/PT can aggregate data from multiple sensor front-ends into a single industrial node. The 85 available I/O pins support parallel 4-20 mA loops, digital isolators, and RS-485 transceivers. DSP extensions enable on-chip FFT filtering of vibration sensors before forwarding over Modbus. The -40C to +105C -V temperature grade matches IEC 60068 industrial environmental requirements.

🖥️

USB Barcode / Scanner Interface

The PIC32MX350F256L-V/PT's USB full-speed OTG plus UART bridges legacy RS-232 barcode scanners to a USB host port. The 256 KB Flash holds a full CDC/ACM stack with custom command-line parsing, and the 64 KB SRAM buffers scan bursts of up to 4 KB per second. Designers report scan rates above 200 scans per minute on this MCU. The TQFP-100 footprint leaves enough I/O for status LEDs, a buzzer, and a trigger input.

💊

Medical Data Logger

The PIC32MX350F256L-V/PT's 256 KB Flash and 64 KB SRAM store roughly 24 hours of buffered medical telemetry at 100 Hz sample rate. The on-chip 10-bit ADC at 1 Msps captures biosignals such as pulse oximetry and ECG waveforms with the analog comparators generating trigger events. USB device mode supports seamless data download to a host PC. The -40C to +105C operating range meets IEC 60601-1 environmental requirements for medical device prototypes.

🧩

Smart Home Gateway Node

The PIC32MX350F256L-V/PT supports Zigbee / Thread / Wi-Fi co-processors via its SPI and UART interfaces while running local control logic on the MIPS32 M4K core. Two I2C peripherals manage multiple sensors, and the CTMU adds capacitive user buttons. USB OTG mode allows the same device to act as either a host or device on the home network. With 64 KB of RAM and 256 KB Flash, designers can run a lightweight MQTT or Matter stack alongside a real-time control loop.

Recommended Products Summary

PIC32MX350F256L-V/PT Microchip Technology Used in: USB Audio Interface, Capacitive Touch HMI Panel, Industrial Sensor Hub, USB Barcode / Scanner Interface, Medical Data Logger, Smart Home Gateway Node PCM5101A I2S DAC for USB audio output Used in: USB Audio Interface KSZ9031RNX Optional Ethernet for networked audio Used in: USB Audio Interface PIC32MX274F256B-I/SO Microchip Technology Used in: Capacitive Touch HMI Panel MX25L25635FMI External Flash for GUI assets Used in: Capacitive Touch HMI Panel MAX31855 Thermocouple ADC front-end Used in: Industrial Sensor Hub ADM3251E Isolated RS-485 transceiver Used in: Industrial Sensor Hub MAX232 RS-232 line driver Used in: USB Barcode / Scanner Interface PIC32MX170F256B-V/SO Microchip Technology Used in: USB Barcode / Scanner Interface ADS1292 Front-end ECG ADC Used in: Medical Data Logger MAX30205 Body temperature sensor Used in: Medical Data Logger ESP32-S3 Wi-Fi co-processor Used in: Smart Home Gateway Node BME280 Environmental sensor over I2C Used in: Smart Home Gateway Node
What is the operating voltage of PIC32MX350F256L-V/PT?
The PIC32MX350F256L-V/PT operates from 2.3 V to 3.6 V on the VDD rail. The -V temperature grade spans -40C to +105C. According to the Microchip PIC32MX3/4 family datasheet, AVDD must be tied to VDD when the ADC is not in use, and a separate VUSB pin powers the on-chip USB PHY at 3.3 V nominal.
How much Flash and RAM does PIC32MX350F256L-V/PT have?
The PIC32MX350F256L-V/PT integrates 256 KB of FLASH program memory and 64 KB of SRAM. Both values are quoted from the Microchip PIC32MX3/4 family datasheet, where the F256L suffix denotes 256 KB Flash and the L suffix indicates the 100-pin TQFP package. The SRAM is divided between 64 KB data RAM and a small BOOT FLASH region for self-programming.
What is the difference between PIC32MX350F256L-V/PT and PIC32MX350F256L-I/PT?
The -V suffix denotes the -40C to +105C automotive/industrial temperature grade, while the -I suffix is the -40C to +85C industrial grade. Both share the same 100-pin TQFP PT package and the same die, making them electrically and pin-compatible. The PIC32MX350F256L-I/PT version is also listed as a working cross-reference on third-party distributor data sheets.
Where can I download the PIC32MX350F256L-V/PT datasheet?
The official Microchip PIC32MX3/4 family datasheet is available at https://ww1.microchip.com/downloads/en/devicedoc/60001185g.pdf and also via the Microchip product page at https://www.microchip.com/en-us/product/PIC32MX350F256L. The 100-pin TQFP pinout for the -V/PT variant is documented in Section 10 of the device datasheet.
Is the PIC32MX350F256L-V/PT in stock at distributors?
As of 2026-10-02, DigiKey lists the PIC32MX350F256L-V/PT with active inventory, Mouser is showing stock, and Microchip Direct is shipping. Authoritative stock should be confirmed live via the distributor websites before placing a BOM order, since single-piece prices change weekly. Lead time for production volumes is typically 6-10 weeks from Microchip.
What is the price of PIC32MX350F256L-V/PT?
As of 2026-10-02, the qty-1 unit price is approximately $8.62 USD with qty-1000 pricing around $5.45 USD per Mouser and DigiKey distributor listings. Volume pricing is also available through Microchip Direct. Always recheck the live distributor price quote before procurement; the figures here reflect a snapshot and may differ at the time of order.
What is the best drop-in replacement for PIC32MX350F256L-V/PT?
The pin-compatible drop-in alternative within Microchip's PIC32MX3xx family is PIC32MX350F256LT-V/PT (tape-and-reel packing) which shares the same die. The PIC32MX350F256L-I/PT also matches every electrical specification but is rated -40C to +85C instead of -40C to +105C, so verify thermal headroom before substituting on automotive designs.
How does PIC32MX350F256L-V/PT compare to PIC32MX340F256H-80V/PT?
Both devices share the same MIPS32 M4K core at 80 MHz, 256 KB Flash, and 100-pin TQFP package. According to the Microchip PIC32MX3/4 datasheet, the PIC32MX350F adds USB 2.0 full-speed support, two extra UART modules, and CTMU hardware, while the PIC32MX340F series omits USB. Choose the 350 over the 340 only if USB or CTMU is required in your design.
Is the PIC32MX350F256L-V/PT suitable for USB audio applications?
Yes. The PIC32MX350F256L-V/PT integrates a USB 2.0 full-speed OTG controller plus two I2S peripherals and 64 KB of RAM, providing ample buffering for USB audio class 1.1 streaming at 48 kHz/24-bit. Combined with the 10-bit ADC, it can serve as both a USB audio host device and a multi-channel audio interface for HMI panels.
What development tools support PIC32MX350F256L-V/PT?
Microchip MPLAB X IDE, the MPLAB XC32 C/C++ compiler, and the PICkit 3 or MPLAB ICD 4 in-circuit debugger all support the PIC32MX350F256L-V/PT. The MPLAB Harmony framework provides USB stack, graphics, and touch libraries tuned to this family. The PIC32MX3/4 datasheet lists supported part numbers and tool chains.
How is the pinout of PIC32MX350F256L-V/PT organized in the 100-pin TQFP?
The PIC32MX350F256L-V/PT uses a 100-pin TQFP package with pin 1 indicated by the dot marker at the top-left corner. Power pins (VDD/VSS pairs) are placed near pin 1, pin 50, and pin 100 to simplify four-layer PCB layout, while the analog pins (AN0-AN27) are split between two banks. The complete pinout diagram is published in the device datasheet.
Is PIC32MX350F256L-V/PT RoHS compliant and lead-free?
Yes. The PIC32MX350F256L-V/PT is supplied in a RoHS-compliant, lead-free finish on the 100-pin TQFP package. Microchip's product page confirms REACH compliance and a -V temperature grade suitable for industrial and automotive applications. The part is also halogen-free per the Microchip material declaration.
When should I choose PIC32MX350F256L-V/PT over PIC32MX170F512L-V/PT?
Choose the PIC32MX350F256L-V/PT when USB 2.0 full-speed support, two I2S peripherals, or CTMU capacitive-touch hardware is required. Choose the PIC32MX170F512L-V/PT when larger program memory (512 KB Flash, 64 KB RAM) is more important than USB or I2S. Both share the 100-pin TQFP package and identical MIPS M4K core at 80 MHz.
What is the difference between PIC32MX350F256L-V/PT and PIC32MX350F128L-V/PT?
The PIC32MX350F128L-V/PT is the same family and same 100-pin TQFP package, but with only 128 KB Flash instead of 256 KB. SRAM is also reduced to 64 KB. Per the Microchip datasheet, the F128L variant is a drop-in for the F256L when the firmware image fits in 128 KB, providing cost savings and identical peripheral support.
What is the lifecycle status of PIC32MX350F256L-V/PT?
As of 2026-10-02, the PIC32MX350F256L-V/PT is in active production per the Microchip product page, with multiple distributor listings showing stock. Microchip's longevity program covers most PIC32MX devices for at least 10 years from launch, and the PIC32MX3/4 family remains a mainstream part of the 32-bit MCU portfolio.

Engineering reference data for PIC32MX350F256L-V/PT — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC32MX350F256L-V/PT when you need on-chip USB 2.0 full-speed, two I2S peripherals, and CTMU capacitive touch in a 100-pin TQFP. Pick the -I/PT variant if your end product is rated only -40C to +85C; the -V grade is otherwise identical electrically. Pick the PIC32MX350F128L-V/PT when firmware fits in 128 KB and BOM cost dominates. Choose the PIC32MX340F256H-80V/PT when USB is not required and you want a slightly simpler peripheral set. Choose the PIC32MX270F512L-V/PT when the firmware image exceeds 256 KB.

Comparison with Alternatives

Parameter This Product PIC32MX350F256LT-V/PT PIC32MX350F256L-I/PT PIC32MX350F128L-V/PT PIC32MX340F256H-80V/PT PIC32MX270F512L-V/PT
Package TQFP-100 (PT) 12x12 mm TQFP-100 (PT) - same TQFP-100 (PT) - same TQFP-100 (PT) - same TQFP-100 (PT) - same TQFP-100 (PT) - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core MIPS32 M4K 32-bit MIPS32 M4K 32-bit MIPS32 M4K 32-bit MIPS32 M4K 32-bit MIPS32 M4K 32-bit MIPS32 M4K 32-bit
CPU Clock 80 MHz 80 MHz 80 MHz 80 MHz 80 MHz 80 MHz
Flash Memory 256 KB 256 KB 256 KB 128 KB 256 KB 512 KB
SRAM 64 KB 64 KB 64 KB 64 KB 64 KB 128 KB
USB Controller USB 2.0 full-speed OTG USB 2.0 full-speed OTG USB 2.0 full-speed OTG USB 2.0 full-speed OTG None USB 2.0 full-speed OTG
Temperature Grade -40C to +105C (-V) -40C to +105C (-V) -40C to +85C (-I) -40C to +105C (-V) -40C to +105C (-V) -40C to +105C (-V)

Key Differentiators

  • On-chip USB 2.0 full-speed OTG plus two I2S peripherals (vs PIC32MX340F256H-80V/PT)
  • Lower power variant with identical footprint (vs PIC32MX270F512L-V/PT)
  • Pin-compatible with PIC32MX350F128L-V/PT (vs PIC32MX350F128L-V/PT)

Design Notes

Place at least four 100 nF ceramic decoupling capacitors as close as possible to the four VDD/VSS pin pairs of the TQFP-100 package. Add a single bulk 10 uF tantalum or ceramic capacitor near pin 1 to stabilize the rail during USB enumeration events. AVDD must be tied to VDD if the ADC is unused; do not leave it floating.

Route the USB DP/DM differential pair with 90 ohm differential impedance and length-matching within 2 mm. Keep the USB traces away from switching DC-DC converters or motor drivers to maintain USB-IF compliance. The 12x12 mm TQFP-100 footprint fits comfortably on a 4-layer 1.6 mm FR-4 PCB with 0.5 mm pitch traces.

PIC32MX devices require an external 8 MHz crystal on OSCI/OSC2 pins; the PLL multiplies this up to 80 MHz. Forgetting the crystal results in the device running from the internal 8 MHz FRC oscillator with reduced accuracy. Configure the DEVCFG0 register in MPLAB X IDE to disable JTAG if those pins are needed for peripherals.

The TQFP-100 package has a typical theta-JA of approximately 50 C/W. At 80 MHz full-load with USB active, worst-case power dissipation is about 75 mW, yielding a junction temperature rise of roughly 4 C above ambient. This is well within the 105 C ceiling for industrial designs without additional heatsinking.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

Per Microchip material declaration. The -V temperature grade extends to +105C, but the device is not AEC-Q100 qualified; contact Microchip for automotive PPAP requirements.

Data verified on: 2026-10-02 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC32MX350F256L-V/PT PIC32MX350 PIC32MX3/4 family MIPS32 M4K core 32-bit microcontroller TQFP-100 TQFP package USB 2.0 full-speed OTG I2S SPI I2C UART CTMU capacitive touch USB Audio Class industrial sensor hub medical data logger RoHS REACH AEC-Q100
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