PIC32MX450F256L-I/TL - 32-bit 256KB Flash MCU 124-VTLA
MPN: PIC32MX450F256L-I/TL ✓ Active| Qty | Unit Price | Extended |
|---|---|---|
| 1 | $9.85 | $9.85 |
| 10 | $8.92 | $89.20 |
| 100 | $7.84 | $784.00 |
| 500 | $6.95 | $3,475.00 |
| 1,000 | $6.2 | $6,200.00 |
PIC32MX450F256L-I/TL Overview
A microcontroller (MCU) is a single-chip computer containing a CPU core, program memory (Flash), working memory (SRAM), and a rich set of peripherals. The PIC32MX4 family occupies the mid-range tier of the Microchip PIC32 portfolio (PIC32MX1/2/3/4/5/6/7), targeting embedded HMI (human-machine interface), audio, USB-device, and graphics designs that demand more memory and I/O than 8/16-bit MCUs while keeping cost and power low. The 32-bit MIPS M4K core delivers deterministic interrupt response and a mature toolchain based on MPLAB X IDE and Harmony.
Key features include 256 KB Flash (256K x 8) supporting self-programming, 64 KB SRAM, Peripheral Pin Select (PPS) for flexible signal routing, an 8-bit Parallel Master Port for graphics LCDs or external memory, and a 10-bit 1 Msps ADC with up to 28 channels. The 2.3 V to 3.6 V operating range and -40 C to +105 C industrial temperature grade make the part suitable for harsh environments, while CTMU enables capacitive touch buttons, sliders, and proximity sensing without external analogue circuitry.
On the architectural side, the M4K pipeline runs up to 80 MHz in the -I (industrial) speed grade of this specific part, while the wider family includes a 120 MHz performance grade. A 5-stage pipeline, hardware multiply/divide, and a tightly-coupled interrupt controller support deterministic real-time behaviour. PPS remaps most digital peripherals to any remappable I/O pin, greatly simplifying PCB routing compared to fixed-function 8-bit PIC MCUs.
Typical applications include USB audio interfaces, HMI control panels with segmented or TFT displays, sensor hubs with CTMU touch, industrial control terminals, and low-cost 32-bit upgrade paths for legacy PIC24/dsPIC designs. The integrated USB OTG also suits the part for CDC/HID/MSD peripherals such as data loggers and configuration tools.
When designing with this MCU, allocate a minimum of 6 mm of unbroken copper ground pour beneath the 124-VTLA exposed pad and use Microchip's recommended land pattern - the part's thermal and electrical performance depends on this pad being soldered. Decouple every VDD/VUSB pair with a 100 nF X7R placed within 2 mm of the pin.
This page synthesises distributor stock, parametric drop-in alternatives, and practical design notes not found in the manufacturer datasheet alone.
Drop-in alternatives for PIC32MX450F256L-I/TL — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.
Variants in this series
Same-series models that are drop-in compatible with PIC32MX450F256L-I/TL (same form factor and footprint) — differing in Package, ADC, Operating Temperature, Core Architecture, USB.
Quick Comparison Tool — Select alternative parts for side-by-side comparison:
PIC32MX450F256L-120/TL
✅ Drop-In✓ In Stock
$5.48 / Unit
View Datasheet →PIC32MX370F512L-I/TL
✅ Drop-In✓ In Stock
$5.31 / Unit
View Datasheet →PIC32MX450F256LT-I/TL
✅ Drop-In✓ In Stock
$5.78 / Unit
View Datasheet →PIC32MX350F256L-V/PT
✅ Drop-In✓ In Stock
$5.45 / Unit
View Datasheet →PIC32MX330F064L-I/TL
✅ Drop-In✓ In Stock
$3.96 / Unit
View Datasheet →PIC32MX274F256DT-I/PT
✅ Drop-In✓ In Stock
$3.29 / Unit
View Datasheet →PIC32MX450F256L-I/TL Maximum Ratings & Electrical Characteristics
| Core Architecture | MIPS32 M4K (PIC32MX) |
| Core/Peripheral Speed | 80 MHz (industrial grade) |
| Maximum Family Speed | 120 MHz / 150 DMIPS |
| Program Flash | 256 KB (256K x 8) |
| SRAM | 64 KB |
| Operating Voltage | 2.3 V to 3.6 V |
| Operating Temperature | -40 C to +105 C (industrial) |
| Package | 124-VTLA (9x9 mm) with exposed pad |
| Mounting Type | Surface Mount |
| Supply Packaging | Tube |
| ADC | 10-bit, 1 Msps, up to 28 channels |
| USB | USB 2.0 Full-Speed OTG |
| I2S / SPI Modules | 2 (SPI with I2S mode) |
| I2C Modules | 2 |
| Analog Comparators | 2 |
| Parallel Master Port (PMP) | 8-bit, for graphics or external memory |
| CTMU | Charge Time Measurement Unit (touch) |
| RTCC | Real-Time Clock and Calendar |
| RoHS Status | Compliant |
PIC32MX450F256L-I/TL 124-vtla (9x9 mm) with exposed pad Pin Configuration Guide
Pin configuration for PIC32MX450F256L-I/TL (124-vtla (9x9 mm) with exposed pad package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.
No detailed pinout data available for PIC32MX450F256L-I/TL.
Refer to the datasheet for full pin configuration.
Typical Applications
PIC32MX450F256L-I/TL is suitable for 6 applications: USB Audio Interface (Codec + I2S Bridge), Industrial HMI Control Panel with TFT Graphics, Capacitive Touch Sensor Hub with CTMU, USB CDC Data Logger / Configuration Tool, Industrial Sensor Hub (Modbus RTU / CAN Gateway), Medical Wellness / Point-of-Care Device.
USB Audio Interface (Codec + I2S Bridge)
The PIC32MX450F256L-I/TL is well-suited to USB audio interface designs because it integrates USB 2.0 Full-Speed OTG (sufficient for 48 kHz / 24-bit stereo USB Audio Class 1 streams) and two independent I2S/SPI ports that can drive a stereo audio codec such as the TI PCM2706 or Cirrus CS4344 in slave mode. The 64 KB SRAM is large enough to host a USB Audio descriptor plus double-buffered PCM samples (~8 KB), and the 256 KB Flash accommodates the USB Audio + HID composite stack from Microchip Harmony. The dual I2S ports also permit simultaneous input/output (full-duplex) capture-and-playback, useful for USB headsets and microphones.
Recommended
Industrial HMI Control Panel with TFT Graphics
The PIC32MX450F256L-I/TL drives colour TFT panels through its 8-bit Parallel Master Port (PMP) running up to the 80 MHz core rate, sufficient for 320x240 QVGA displays at 30 fps when paired with a graphics controller such as the Solomon Systech SSD1963 or RA8875. The 124-pin VTLA package exposes the full PMP bus plus 28 ADC channels for analogue sensor inputs (e.g., 4-20 mA loops, RTD, potentiometers). CTMU adds touch-button support for up to 16 capacitive keys, eliminating an external touch IC. Industrial -40 C to +105 C operation makes the panel viable for factory automation without thermal derating.
Recommended
Capacitive Touch Sensor Hub with CTMU
The CTMU (Charge Time Measurement Unit) inside the PIC32MX450F256L-I/TL enables accurate time-based capacitance measurement by combining a constant current source with an ADC timer capture, supporting capacitive touch buttons, sliders, and proximity sensors without dedicated touch ICs. The 28 ADC channels and 2 analog comparators allow multiplexing up to 32 touch electrodes via external analog switches, while the 64 KB SRAM can hold gesture-recognition firmware or a real-time debounce/filter pipeline. Operating voltage 2.3-3.6 V suits both battery-powered and mains-attached appliances.
Recommended
USB CDC Data Logger / Configuration Tool
With USB 2.0 Full-Speed OTG and 256 KB Flash, the PIC32MX450F256L-I/TL is well-matched to USB-CDC or USB-MSD data-logger designs where the host sees the device as a virtual COM port or removable drive. The 64 KB SRAM buffers several hours of 16-bit 100 Hz ADC samples without external memory, and 256 KB Flash stores persistent configuration plus bootloader. Industrial -40 C to +105 C temperature range supports outdoor or factory deployment. Real-Time Clock and Calendar (RTCC) with backup battery input enables timestamping during field deployment.
Recommended
Industrial Sensor Hub (Modbus RTU / CAN Gateway)
The PIC32MX450F256L-I/TL serves as a 32-bit bridge between legacy RS-485 Modbus RTU sensors and modern USB / Ethernet / CAN networks, leveraging its dual I2C, dual I2S/SPI, and 28 ADC channels to aggregate field sensor data. The 64 KB SRAM hosts a Modbus master or slave stack, while the 80 MHz M4K core performs deterministic polling of multiple Modbus nodes. Pairing with an external CAN MCP2515 over SPI extends the gateway to industrial CAN networks. The -40 C to +105 C industrial grade matches IEC 60068 environmental profiles.
Recommended
Medical Wellness / Point-of-Care Device
In non-critical medical-wellness designs (thermometers, pulse oximeter front-ends, body-composition monitors), the PIC32MX450F256L-I/TL delivers 32-bit DSP-style maths at 80 MHz for pulse-rate and SpO2 algorithms using its 1 Msps 10-bit ADC. The 256 KB Flash holds signal-processing firmware plus USB-CDC virtual COM for PC connectivity, while 64 KB SRAM provides FFT and moving-average filter headroom. The CTMU can be repurposed as a precision timer for optical sensor LED driving. Industrial temperature range and RoHS compliance support medical wellness regulatory baselines.
Recommended
Recommended Products Summary
Engineering reference data for PIC32MX450F256L-I/TL — comparison, design guidance, and compliance information.
Selection Guide
Comparison with Alternatives
| Parameter | This Product | PIC32MX450F256L-120/TL | PIC32MX370F512L-I/TL | PIC32MX450F256LT-I/TL | PIC32MX350F256L-V/PT | PIC32MX330F064L-I/TL | PIC32MX274F256DT-I/PT |
|---|---|---|---|---|---|---|---|
| Brand | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology |
| Package | 124-VTLA (9x9 mm) | 124-VTLA (9x9 mm) | 124-VTLA (9x9 mm) | 124-VTLA (9x9 mm) | 124-VTLA family | 124-VTLA family | 124-VTLA family |
| Core Speed (grade) | 80 MHz | 120 MHz | 96 MHz | 80 MHz | 72 MHz | 80 MHz | 80 MHz |
| Flash | 256 KB | 256 KB | 512 KB | 256 KB | 256 KB | 64 KB | 256 KB |
| SRAM | 64 KB | 64 KB | 128 KB | 64 KB | 64 KB | 16 KB | 64 KB |
| USB | USB 2.0 FS OTG | USB 2.0 FS OTG | USB 2.0 FS OTG | USB 2.0 FS OTG | USB 2.0 FS OTG | USB 2.0 FS OTG | USB 2.0 FS OTG |
| I2S / SPI Modules | 2 | 2 | 2 | 2 | 1 | 2 | 2 |
| CTMU Touch | Yes | Yes | Yes | Yes | No | Yes | Yes |
| Operating Temperature | -40 C to +105 C | -40 C to +85 C (commercial) | -40 C to +105 C | -40 C to +105 C | -40 C to +105 C (V grade) | -40 C to +105 C | -40 C to +85 C |
Key Differentiators
- Industrial -40 C to +105 C temperature grade at 80 MHz in the same VTLA package (vs PIC32MX450F256L-120/TL)
- Tube packaging for production-line prototyping and low-volume OEM builds (vs PIC32MX450F256LT-I/TL)
- CTMU plus dual I2S in 124-VTLA at 80 MHz industrial (vs PIC32MX350F256L-V/PT)
Design Notes
Estimated: at 80 MHz full-core activity with USB and PMP active, the PIC32MX450F256L-I/TL draws approximately 50-70 mA from VDD (3.3 V). The 124-VTLA package dissipates heat primarily through the exposed pad on its underside, which must be soldered to a ground-pour copper area of at least 25 mm x 25 mm with a thermal via array of 0.3 mm vias on a 1 mm pitch. Without this pad connection, junction temperature can exceed 105 C at full load in still air, so always follow Microchip's recommended land pattern from the package datasheet.
Decouple every VDD/VSS pin pair with a 100 nF X7R ceramic placed within 2 mm of the pin, and add a single bulk 4.7 uF to 10 uF tantalum or ceramic near the package. The VUSB pin needs its own 100 nF + 4.7 uF combination. Keep crystal traces short (<5 mm) and guard them with a ground ring; the secondary 32.768 kHz crystal for the RTCC should also be guarded. The USB D+/D- traces require 90-ohm differential impedance, so route them over a continuous ground plane.
Do not connect a 5 V signal to any I/O pin - all PIC32MX digital I/O are 3.3 V tolerant only and exceeding this damages the silicon. The MCLR pin must be pulled up to VDD through a 10 kohm resistor for normal operation; leave it floating only when you understand the in-circuit serial programming (ICSP) implications. For bootloader designs, reserve PGEC1/PGED1 for ICSP even if you also use those pins as GPIO. The ADC's maximum 1 Msps rate requires the S&H capacitor to fully settle - add 10-100 ohm source impedance buffers if your sensor output exceeds 5 kohm.
Peripheral Pin Select (PPS) lets you remap most digital peripherals to almost any remappable I/O pin, but the analog pins (ANx) are fixed and cannot be remapped. When laying out a PCB with USB, PMP, and ADC simultaneously, plan the analog and digital pin groups carefully before placing parts - swapping a digital pin to an analog function later requires a board respin. Reserve PGECx/PGEDx pairs for ICSP/ICD on accessible board edges to ease field programming.
Compliance Information
RoHS and REACH compliance per Microchip product environmental certification page. AEC-Q100 not applicable for general-purpose MCU; no automotive-qualified variant of PIC32MX450F256L-I/TL exists in the active catalogue. Lead-free and halogen-free per Microchip package marking.
