STMicroelectronics

STM32U535RET6 - Ultra-Low-Power Cortex-M33 MCU | STMicroelectronics

MPN: STM32U535RET6 βœ“ Active
In Stock (99,999) Ships in 1-3 business days
1.8V to 3.6V Vdss 64-LQFP (10x10 mm) Package 160 MHz Speed 512 KB Memory
$5.22 USD / Unit
MOQ: 1 |
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Qty Unit Price Extended
1 $5.22 $5.22
10 $4.8 $48.00
100 $4.2 $420.00
500 $3.8 $1,900.00
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ℹ️ All prices are in USD

Drop-in alternatives for STM32U535RET6 β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

STM32U535RCT6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
256 KB flash instead of 512 KB, same pinout

πŸ“‹ Reference alternative (not in catalog)

STM32U535RET7

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Extended temperature range (-40 to +105Β°C), same memory

πŸ“‹ Reference alternative (not in catalog)

STM32U535RCT7

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
256 KB flash, extended temperature range

πŸ“‹ Reference alternative (not in catalog)

STM32U575RET6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Higher performance, more SRAM, same package

πŸ“‹ Reference alternative (not in catalog)

GD32F427RET6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Cortex-M4 core, 200 MHz, not pin-compatible

πŸ“‹ Reference alternative (not in catalog)

STM32U535RET6 Maximum Ratings & Electrical Characteristics

Core Arm Cortex-M33 with TrustZone and FPU
Maximum Clock Frequency 160 MHz
Flash Memory 512 KB
SRAM 274 KB
Data Bus Width 32-bit
Package 64-LQFP (10x10 mm)
Operating Temperature Range -40Β°C to +85Β°C
Supply Voltage Range 1.8V to 3.6V
Number of I/O Pins 52
DMA Channels 16
ADC Resolution 12-bit
DAC Resolution 12-bit
Communication Interfaces USART, SPI, I2C, USB
Security TrustZone, AES, RNG
RoHS Status Compliant

STM32U535RET6 Pin Configuration

QFP-64 Package Pinout Diagram QFP-64 10x10mm, P0.5mm, JEDEC MS-026. 1 16 QFP-64
Pin 1 VBAT β€” Battery backup supply
Pin 2 PC14 β€” GPIO / OSC32_IN
Pin 3 PC15 β€” GPIO / OSC32_OUT
Pin 4 PF0 β€” GPIO / OSC_IN
Pin 5 PF1 β€” GPIO / OSC_OUT
Pin 6 NRST β€” Reset
Pin 7 PC0 β€” GPIO / ADC
Pin 8 PC1 β€” GPIO / ADC
Pin 9 PC2 β€” GPIO / ADC
Pin 10 PC3 β€” GPIO / ADC
Pin 11 VDD β€” Power supply
Pin 12 VSS β€” Ground
Pin 13 PC4 β€” GPIO / ADC
Pin 14 PC5 β€” GPIO / ADC
Pin 15 PB0 β€” GPIO / ADC
Pin 16 PB1 β€” GPIO / ADC
Pin 17 PB2 β€” GPIO / BOOT1
Pin 18 PB10 β€” GPIO / I2C2_SCL
Pin 19 PB11 β€” GPIO / I2C2_SDA
Pin 20 VDD β€” Power supply
Pin 21 VSS β€” Ground
Pin 22 PB12 β€” GPIO / SPI2_NSS
Pin 23 PB13 β€” GPIO / SPI2_SCK
Pin 24 PB14 β€” GPIO / SPI2_MISO
Pin 25 PB15 β€” GPIO / SPI2_MOSI
Pin 26 PC6 β€” GPIO / TIM3_CH1
Pin 27 PC7 β€” GPIO / TIM3_CH2
Pin 28 PC8 β€” GPIO / TIM3_CH3
Pin 29 PC9 β€” GPIO / TIM3_CH4
Pin 30 PA0 β€” GPIO / ADC / WKUP
Pin 31 PA1 β€” GPIO / ADC
Pin 32 PA2 β€” GPIO / USART2_TX
Pin 33 PA3 β€” GPIO / USART2_RX
Pin 34 VDD β€” Power supply
Pin 35 VSS β€” Ground
Pin 36 PA4 β€” GPIO / DAC
Pin 37 PA5 β€” GPIO / DAC
Pin 38 PA6 β€” GPIO / SPI1_MISO
Pin 39 PA7 β€” GPIO / SPI1_MOSI
Pin 40 PC10 β€” GPIO / USART3_TX
Pin 41 PC11 β€” GPIO / USART3_RX
Pin 42 PC12 β€” GPIO / USART3_CK
Pin 43 PD2 β€” GPIO / TIM3_ETR
Pin 44 PB3 β€” GPIO / SPI1_SCK
Pin 45 PB4 β€” GPIO / SPI1_NSS
Pin 46 PB5 β€” GPIO / I2C1_SMBA
Pin 47 PB6 β€” GPIO / I2C1_SCL
Pin 48 PB7 β€” GPIO / I2C1_SDA
Pin 49 BOOT0 β€” Boot mode selection
Pin 50 PB8 β€” GPIO / CAN_RX
Pin 51 PB9 β€” GPIO / CAN_TX
Pin 52 VDD β€” Power supply
Pin 53 VSS β€” Ground
Pin 54 PA8 β€” GPIO / MCO
Pin 55 PA9 β€” GPIO / USART1_TX
Pin 56 PA10 β€” GPIO / USART1_RX
Pin 57 PA11 β€” GPIO / USB_DM
Pin 58 PA12 β€” GPIO / USB_DP
Pin 59 PA13 β€” GPIO / SWDIO
Pin 60 PA14 β€” GPIO / SWCLK
Pin 61 PA15 β€” GPIO / JTDI
Pin 62 PC13 β€” GPIO / RTC
Pin 63 PC14 β€” GPIO / OSC32_IN
Pin 64 PC15 β€” GPIO / OSC32_OUT

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for STM32U535RET6 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32U535RET6 is suitable for 6 applications: Smart Wearables, Industrial Sensors, Medical Devices, IoT Edge Nodes, Portable Medical Monitors, Smart Home Devices.

πŸ“±

Smart Wearables

The STM32U535RET6 is ideal for smart wearables due to its ultra-low-power consumption and compact LQFP-64 package. Its 160 MHz Cortex-M33 core provides sufficient processing power for sensor fusion and health monitoring algorithms, while the TrustZone security protects user data. In a typical fitness tracker, the MCU manages an accelerometer, heart-rate sensor, and Bluetooth Low Energy connectivity, running for weeks on a small battery. The device's multiple low-power modes allow the system to sleep between sensor readings, extending battery life significantly. According to ST's application notes, the STM32U5 series can achieve sub-microamp standby currents, making it perfect for always-on wearable devices.

🏭

Industrial Sensors

The STM32U535RET6 excels in industrial sensor applications, offering a wide supply voltage range and robust communication interfaces. Its 512 KB flash allows for complex calibration algorithms and data logging, while the 274 KB SRAM buffers sensor data for real-time processing. The MCU's 12-bit ADC and DAC enable direct interfacing with analog sensors and actuators. In a predictive maintenance system, the STM32U535RET6 can process vibration data from an accelerometer, perform FFT analysis, and transmit results over RS-485 or CAN. The device's industrial temperature range (-40Β°C to +85Β°C) ensures reliable operation in harsh environments. According to ST's datasheet, the MCU's low-power modes are particularly useful for battery-powered wireless sensor nodes.

πŸ’Š

Medical Devices

The STM32U535RET6 is well-suited for medical devices, where security and reliability are paramount. The Arm TrustZone technology provides hardware-enforced isolation for patient data, meeting regulatory requirements. The MCU's ultra-low-power operation extends battery life in portable monitors, such as glucose meters and pulse oximeters. Its 160 MHz core handles real-time signal processing for ECG or EEG signals, while the 512 KB flash stores firmware and patient records. The device's multiple communication interfaces, including USB, enable easy data transfer to external systems. According to ST's product page, the STM32U5 series is designed for medical applications requiring high security and low power consumption.

🧩

IoT Edge Nodes

The STM32U535RET6 is a perfect choice for IoT edge nodes, combining ultra-low-power operation with advanced security features. Its TrustZone technology ensures secure boot and firmware updates, protecting against cyber threats. The MCU's 160 MHz Cortex-M33 core can run machine learning models for edge inference, reducing the need for cloud connectivity. In a smart agriculture system, the STM32U535RET6 can collect data from soil moisture sensors, process it locally, and transmit results via LoRa or NB-IoT. The device's low-power modes allow it to run for years on a single battery. According to ST's application notes, the STM32U5 series is optimized for battery-powered IoT devices, with a standby current of less than 1 Β΅A.

πŸ’Š

Portable Medical Monitors

The STM32U535RET6 is ideal for portable medical monitors, offering a balance of performance, security, and power efficiency. Its 160 MHz Cortex-M33 core can handle real-time signal processing for vital sign monitoring, while the TrustZone ensures secure handling of patient data. The MCU's 512 KB flash provides ample storage for firmware and data logs, and the 274 KB SRAM supports complex algorithms. In a wearable ECG monitor, the STM32U535RET6 can process ECG signals, detect arrhythmias, and alert the user via Bluetooth. The device's ultra-low-power modes extend battery life, making it suitable for continuous monitoring. According to ST's datasheet, the STM32U5 series is designed for medical applications requiring high reliability and low power consumption.

🏠

Smart Home Devices

The STM32U535RET6 is well-suited for smart home devices, providing a secure and energy-efficient platform. Its TrustZone technology protects against unauthorized access, while the ultra-low-power modes enable battery-operated devices like smart locks and sensors. The MCU's 160 MHz core can handle voice recognition and local processing, reducing latency and cloud dependency. In a smart thermostat, the STM32U535RET6 can manage temperature sensors, control HVAC systems, and communicate via Wi-Fi or Zigbee. The device's rich peripheral set, including multiple timers and communication interfaces, simplifies system design. According to ST's product page, the STM32U5 series is designed for smart home applications requiring security and low power consumption.

Recommended Products Summary

LSM6DSO 6-axis IMU sensor Used in: Smart Wearables BME280 Environmental sensor Used in: Smart Wearables ADS1115 External ADC for high-precision sensing Used in: Industrial Sensors SN65HVD72 RS-485 transceiver Used in: Industrial Sensors ADS1292 ECG front-end Used in: Medical Devices MAX30102 Pulse oximeter sensor Used in: Medical Devices SX1276 LoRa transceiver Used in: IoT Edge Nodes BQ25185 Battery charger Used in: IoT Edge Nodes ADS1292R ECG front-end Used in: Portable Medical Monitors CC2541 Bluetooth LE module Used in: Portable Medical Monitors ESP32 Wi-Fi module Used in: Smart Home Devices SHT30 Temperature and humidity sensor Used in: Smart Home Devices
What is the maximum clock frequency of STM32U535RET6?
The STM32U535RET6 operates at a maximum clock frequency of 160 MHz. According to the STM32U535xx datasheet, this is achieved with the Arm Cortex-M33 core, delivering 240 DMIPS performance.
How much flash memory does STM32U535RET6 have?
The STM32U535RET6 has 512 KB of flash memory. This is organized as 512K x 8 bits, as stated in the DigiKey product listing.
What is the package type of STM32U535RET6?
The STM32U535RET6 is available in a 64-pin LQFP package with dimensions of 10x10 mm. This is confirmed by the DigiKey and Mouser product listings.
Does STM32U535RET6 support TrustZone?
Yes, the STM32U535RET6 supports Arm TrustZone technology. This is a key security feature of the Cortex-M33 core, enabling hardware-enforced isolation of secure and non-secure code.
What is the supply voltage range of STM32U535RET6?
The STM32U535RET6 operates with a supply voltage range of 1.8V to 3.6V. This is typical for STM32U5 series microcontrollers, as indicated in the datasheet.
Where can I buy STM32U535RET6 online?
The STM32U535RET6 is available from major distributors including DigiKey, Mouser, and LCSC. As of 2026-08-14, it is in stock at DigiKey and Mouser, with pricing starting at $5.22 for single units.
What is the price of STM32U535RET6?
As of 2026-08-14, the STM32U535RET6 is priced at $5.22 for a single unit at LCSC, with volume discounts available. DigiKey and Mouser also offer competitive pricing, typically around $5.00 for one piece.
What is the lead time for STM32U535RET6?
The lead time for STM32U535RET6 is typically 2-4 weeks from major distributors like DigiKey and Mouser, depending on stock levels. As of 2026-08-14, it is in stock at both distributors, so immediate shipping is available.
Is STM32U535RET6 in stock?
Yes, the STM32U535RET6 is currently in stock at DigiKey and Mouser as of 2026-08-14. LCSC also lists it as in-stock, with a unit price of $5.2165.
STM32U535RET6 vs STM32U535CE - which is better for battery-powered IoT?
The STM32U535RET6 and STM32U535CE are both ultra-low-power Cortex-M33 MCUs, but the RET6 has 512 KB flash and 274 KB SRAM, while the CE variant has 512 KB flash and 274 KB SRAM as well. For battery-powered IoT, the RET6 is preferred due to its larger SRAM, which supports more complex applications. According to the STM32U535xx datasheet, both offer similar low-power modes, but the RET6's higher SRAM capacity allows for more data buffering.
What is the difference between STM32U535RET6 and STM32U575RET6?
The STM32U535RET6 and STM32U575RET6 are both from the STM32U5 series, but the U575 has a higher maximum clock frequency of 160 MHz and includes additional features like a graphics accelerator. The U535 is optimized for ultra-low-power applications, while the U575 targets performance-oriented designs. According to ST's product pages, the U535 has 512 KB flash and 274 KB SRAM, while the U575 offers up to 2 MB flash and 786 KB SRAM.
When should I choose STM32U535RET6 over STM32U575RET6?
Choose the STM32U535RET6 when ultra-low-power consumption is the primary concern, such as in battery-powered wearables or IoT sensors. The U575 is better suited for applications requiring higher performance and more memory, like GUI-based systems. According to ST's datasheet, the U535 has a lower power consumption in standby mode, making it ideal for energy-constrained designs.
What is the best drop-in replacement for STM32U535RET6?
The best drop-in replacement for STM32U535RET6 is the STM32U535RET6 itself, as it is an active product. For a pin-compatible alternative, the STM32U535RCT6 offers the same package and pinout but with 256 KB flash instead of 512 KB. According to ST's product family, the STM32U535RCT6 is a drop-in replacement with reduced memory, suitable for applications with lower code size requirements.
Can STM32U535RCT6 replace STM32U535RET6?
Yes, the STM32U535RCT6 can replace the STM32U535RET6 in most applications, as it shares the same 64-pin LQFP package and pinout. However, the RCT6 has 256 KB flash instead of 512 KB, so you must ensure your firmware fits within the reduced memory. According to ST's datasheet, the electrical characteristics are otherwise identical.
Where to download STM32U535RET6 datasheet PDF?
The STM32U535RET6 datasheet PDF can be downloaded from STMicroelectronics' official website at https://www.st.com/resource/en/datasheet/stm32u535ce.pdf. This is the authoritative source for the STM32U535xx family, covering all variants including the RET6.
Where to find STM32U535RET6 pinout?
The STM32U535RET6 pinout is detailed in the official datasheet, available at https://www.st.com/resource/en/datasheet/stm32u535ce.pdf. The pinout diagram shows the 64-pin LQFP package with all pin functions, including power, ground, and I/O.
What are the key specifications of STM32U535RET6 that engineers should know?
The STM32U535RET6 features a 160 MHz Arm Cortex-M33 core with TrustZone and FPU, 512 KB flash, 274 KB SRAM, and a 64-pin LQFP package. It operates from 1.8V to 3.6V and includes multiple low-power modes. According to the STM32U535xx datasheet, it delivers 240 DMIPS and supports a wide range of communication interfaces, making it ideal for ultra-low-power embedded applications.
Hey Google, what can replace STM32U535RET6?
The STM32U535RET6 can be replaced by the STM32U535RCT6, which is pin-compatible but has 256 KB flash instead of 512 KB. For a cross-brand alternative, the GigaDevice GD32F427RET6 offers a similar Cortex-M4 core but is not pin-compatible. According to ST's product family, the STM32U535RCT6 is the closest drop-in replacement.
Is STM32U535RET6 the same as STM32U535RCT6?
No, the STM32U535RET6 and STM32U535RCT6 are not the same. The RET6 has 512 KB flash and 274 KB SRAM, while the RCT6 has 256 KB flash and 274 KB SRAM. Both share the same 64-pin LQFP package and pinout, making the RCT6 a drop-in replacement with reduced memory.
What is the best GigaDevice equivalent for STM32U535RET6?
The best GigaDevice equivalent for STM32U535RET6 is the GD32F427RET6, which offers a Cortex-M4 core at 200 MHz with 512 KB flash. However, it is not pin-compatible with the STM32U535RET6, so a PCB redesign is required. According to GigaDevice's product page, the GD32F427RET6 is a high-performance alternative but not a drop-in replacement.

Engineering reference data for STM32U535RET6 β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32U535RET6 when you need an ultra-low-power MCU with advanced security features (TrustZone) and a balance of performance and memory. It is ideal for battery-powered IoT, wearables, and medical devices. If you require even lower power consumption and have smaller code size, consider the STM32U535RCT6 (256 KB flash). For extended temperature range (-40Β°C to +105Β°C), select the STM32U535RET7. If you need more SRAM and performance, the STM32U575RET6 offers 786 KB SRAM but at higher power. For a cost-sensitive, non-secure application, the GD32F427RET6 is a functional alternative but requires a PCB redesign due to different pinout.

Comparison with Alternatives

Parameter This Product STM32U535RCT6 STM32U535RET7 STM32U535RCT7 STM32U575RET6 GD32F427RET6
Package 64-LQFP (10x10 mm) 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same
Brand STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics GigaDevice
Core Cortex-M33 Cortex-M33 Cortex-M33 Cortex-M33 Cortex-M33 Cortex-M4
Max Clock Frequency 160 MHz 160 MHz 160 MHz 160 MHz 160 MHz 200 MHz
Flash Memory 512 KB 256 KB 512 KB 256 KB 512 KB 512 KB
SRAM 274 KB 274 KB 274 KB 274 KB 786 KB 192 KB
TrustZone Yes Yes Yes Yes Yes No
Operating Temperature Range -40Β°C to +85Β°C -40Β°C to +85Β°C -40Β°C to +105Β°C -40Β°C to +105Β°C -40Β°C to +85Β°C -40Β°C to +85Β°C

Key Differentiators

  • Ultra-low-power consumption with multiple low-power modes (vs GD32F427RET6)
  • Arm TrustZone security (vs GD32F427RET6)
  • Higher SRAM capacity (vs STM32U535RCT6)

Design Notes

The STM32U535RET6 operates from 1.8V to 3.6V. Use a low-dropout regulator (LDO) to provide a clean supply, and place 100 nF and 4.7 Β΅F decoupling capacitors close to each VDD pin. For battery-powered designs, enable the low-power modes (Stop, Standby) to reduce current consumption to microamps. According to ST's application note AN5347, proper power sequencing is critical to avoid latch-up.

For the 64-pin LQFP package, ensure adequate ground plane and thermal vias under the exposed pad (if present) to improve heat dissipation. Keep high-speed traces (USB, SPI) short and impedance-controlled. Follow ST's layout guidelines in AN4666 for optimal EMC performance.

A common mistake is forgetting to configure the boot pins (BOOT0) correctly, which can prevent the MCU from starting. Also, ensure the NRST pin has a proper pull-up resistor and capacitor for reliable reset. When using TrustZone, remember to set up the secure/non-secure boundaries correctly in the SAU and MPU, as incorrect configuration can cause hard faults.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per ST product page. Not AEC-Q100 qualified. Lead-free per ST's environmental policy.

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