STMicroelectronics

STM32L562RET6 - 512KB Flash, 110MHz Cortex-M33 MCU | STMicroelectronics

Name: STM32L562RET6
Brand: STMicroelectronics
Price: 8.50 USD
Availability: InStock

MPN: STM32L562RET6 ✓ Active

In Stock (99,999) Ships in 1-3 business days

1.71 V to 3.6 V Vdss 100 nA (typical) Id LQFP64 (10x10 mm) Package 110 MHz Speed 512 KB Memory

$8.5 USD / Unit

MOQ: 1 |

Volume Pricing

Qty	Unit Price	Extended
1	$8.5	$8.50
10	$7.65	$76.50
100	$6.8	$680.00
500	$6.12	$3,060.00
1,000	$5.44	$5,440.00

ℹ️ All prices are in USD

View Datasheet (PDF) View Alternatives

Quantity

Drop-in alternatives for STM32L562RET6 — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

STM32L552RET6

✅ Drop-In

STMicroelectronics

📦 LQFP64

Arm Cortex-M33 with TrustZone · 110 MHz · 512 KB · 256 KB · 1.71 V to 3.6 V · -40C to +85C · LQFP-64 (10x10 mm) · 51

✓ 99,999 In Stock

$5.44 / Unit

View Datasheet →

STM32L562REI6

✅ Drop-In

📦 LQFP64

Same package, but with 512 KB flash and 256 KB SRAM, same security features

📋 Reference alternative (not in catalog)

STM32L562RCT6

✅ Drop-In

📦 LQFP64

Same package, but with 256 KB flash and 128 KB SRAM

📋 Reference alternative (not in catalog)

ℹ️ 1 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

STM32L562RET6 Maximum Ratings & Electrical Characteristics

Core	Arm Cortex-M33 with TrustZone
Maximum Clock Frequency	110 MHz
Flash Memory	512 KB
SRAM	256 KB
Supply Voltage Range	1.71 V to 3.6 V
Operating Temperature Range	-40C to +85C
Package	LQFP64 (10x10 mm)
Mounting Type	Surface Mount
Number of I/O Pins	51
ADC Resolution	12-bit
ADC Channels	16
DAC Channels	2 (12-bit)
Communication Interfaces	USART, SPI, I2C, USB OTG FS, SAI, CAN
Standby Current	100 nA (typical)
RoHS Status	Compliant

STM32L562RET6 Pin Configuration

Pin 1	VBAT — Battery backup supply for RTC and backup registers
Pin 2	PC13 — GPIO, tamper, RTC output
Pin 3	PC14 — GPIO, OSC32_IN
Pin 4	PC15 — GPIO, OSC32_OUT
Pin 5	PF0 — GPIO, OSC_IN
Pin 6	PF1 — GPIO, OSC_OUT
Pin 7	NRST — Reset (active low)
Pin 8	VDD — Digital power supply
Pin 9	VSS — Ground
Pin 10	PA0 — GPIO, ADC input, WKUP
Pin 11	PA1 — GPIO, ADC input
Pin 12	PA2 — GPIO, USART2_TX, ADC input
Pin 13	PA3 — GPIO, USART2_RX, ADC input
Pin 14	PA4 — GPIO, DAC_OUT1, ADC input
Pin 15	PA5 — GPIO, DAC_OUT2, ADC input
Pin 16	PA6 — GPIO, SPI1_MISO, ADC input
Pin 17	PA7 — GPIO, SPI1_MOSI, ADC input
Pin 18	PA8 — GPIO, USB_OTG_FS_SOF
Pin 19	PA9 — GPIO, USB_OTG_FS_VBUS
Pin 20	PA10 — GPIO, USB_OTG_FS_ID
Pin 21	PA11 — GPIO, USB_OTG_FS_DM
Pin 22	PA12 — GPIO, USB_OTG_FS_DP
Pin 23	PA13 — GPIO, SWDIO
Pin 24	PA14 — GPIO, SWCLK
Pin 25	PA15 — GPIO, JTDI
Pin 26	VDD — Digital power supply
Pin 27	VSS — Ground
Pin 28	PB0 — GPIO, ADC input
Pin 29	PB1 — GPIO, ADC input
Pin 30	PB2 — GPIO, BOOT1
Pin 31	PB3 — GPIO, SPI1_SCK
Pin 32	PB4 — GPIO, SPI1_NSS
Pin 33	PB5 — GPIO, I2C1_SMBA
Pin 34	PB6 — GPIO, I2C1_SCL
Pin 35	PB7 — GPIO, I2C1_SDA
Pin 36	PB8 — GPIO, I2C1_SCL
Pin 37	PB9 — GPIO, I2C1_SDA
Pin 38	PB10 — GPIO, I2C2_SCL
Pin 39	PB11 — GPIO, I2C2_SDA
Pin 40	VDD — Digital power supply
Pin 41	VSS — Ground
Pin 42	PB12 — GPIO, SPI2_NSS
Pin 43	PB13 — GPIO, SPI2_SCK
Pin 44	PB14 — GPIO, SPI2_MISO
Pin 45	PB15 — GPIO, SPI2_MOSI
Pin 46	PC0 — GPIO, ADC input
Pin 47	PC1 — GPIO, ADC input
Pin 48	PC2 — GPIO, ADC input
Pin 49	PC3 — GPIO, ADC input
Pin 50	PC4 — GPIO, ADC input
Pin 51	PC5 — GPIO, ADC input
Pin 52	PC6 — GPIO, USART6_TX
Pin 53	PC7 — GPIO, USART6_RX
Pin 54	PC8 — GPIO, USART6_CK
Pin 55	PC9 — GPIO, I2C3_SDA
Pin 56	PC10 — GPIO, USART3_TX
Pin 57	PC11 — GPIO, USART3_RX
Pin 58	PC12 — GPIO, USART3_CK
Pin 59	PC13 — GPIO, RTC_TAMP1
Pin 60	PC14 — GPIO, OSC32_IN
Pin 61	PC15 — GPIO, OSC32_OUT
Pin 62	VDD — Digital power supply
Pin 63	VSS — Ground
Pin 64	VDDA — Analog power supply

Safe Operating Area (SOA) & Thermal Characteristics

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32L562RET6 is suitable for 6 applications: Secure IoT Nodes, Wearable Health Monitors, Smart Meters, Industrial Sensors, Battery-Powered Medical Devices, Smart Home Controllers.

🧩

Secure IoT Nodes

The STM32L562RET6 is ideal for secure IoT nodes that require hardware-enforced security and ultra-low power consumption. Its TrustZone technology isolates critical code and data, while the cryptographic accelerator enables secure communication with cloud services. In a typical IoT node, the MCU collects sensor data, encrypts it, and transmits it via Wi-Fi or LoRa. The low standby current of 100 nA ensures long battery life, making it suitable for battery-powered sensors deployed in remote locations. The 110 MHz Cortex-M33 core provides sufficient processing power for edge AI and data preprocessing, reducing the need for cloud processing.

Recommended

SX1262 (LoRa transceiver for wireless communication) BME280 (Environmental sensor for temperature, humidity, and pressure)

💊

Wearable Health Monitors

The STM32L562RET6 is well-suited for wearable health monitors that require continuous operation on a small battery. Its ultra-low-power modes, including a standby current of 100 nA, allow the device to run for weeks or months on a single charge. The MCU can process biometric signals from sensors such as heart rate monitors and accelerometers, and securely transmit data to a smartphone via Bluetooth Low Energy. The TrustZone security ensures that personal health data is protected from unauthorized access. The 12-bit ADC with 16 channels provides accurate analog signal acquisition for sensor interfaces.

Recommended

MAX30102 (Pulse oximeter and heart-rate sensor) LSM6DSO (Accelerometer and gyroscope for motion tracking)

⚡

Smart Meters

The STM32L562RET6 is an excellent choice for smart meters that require secure data logging and communication. Its low power consumption allows the meter to operate on battery power for extended periods, while the cryptographic accelerator ensures that consumption data is securely transmitted to the utility company. The MCU can interface with current and voltage sensors via its ADC, and communicate via M-Bus or PLC modems. The TrustZone security protects the meter's firmware from tampering, ensuring accurate billing and preventing energy theft.

Recommended

RN8302B (Energy metering IC for power measurement) S2-LP (Sub-GHz transceiver for wireless communication)

🏭

Industrial Sensors

The STM32L562RET6 is suitable for industrial sensors that require reliable operation in harsh environments. Its wide operating temperature range of -40°C to +85°C and robust communication interfaces (CAN, UART, SPI) make it ideal for factory automation and process control. The MCU can process sensor data, perform local analytics, and communicate with a central controller via industrial protocols. The TrustZone security ensures that firmware updates are authenticated, preventing malicious code injection. The low power consumption also enables battery-powered wireless sensors in remote industrial sites.

Recommended

TMP117 (High-accuracy temperature sensor) ADXL345 (Digital accelerometer for vibration monitoring)

💊

Battery-Powered Medical Devices

The STM32L562RET6 is ideal for battery-powered medical devices such as glucose monitors, insulin pumps, and portable diagnostic tools. Its ultra-low power consumption extends battery life, while the TrustZone security protects patient data and ensures the integrity of medical algorithms. The MCU's cryptographic accelerator enables secure communication with healthcare providers, and the 12-bit ADC provides accurate readings from biosensors. The device's small LQFP64 package allows for compact designs, and its wide supply voltage range accommodates various battery chemistries.

Recommended

AFE4404 (Analog front-end for optical heart-rate monitoring) BQ25185 (Battery charger IC for Li-ion batteries)

🏠

Smart Home Controllers

The STM32L562RET6 can serve as the central controller in smart home systems, managing lighting, HVAC, and security devices. Its multiple communication interfaces (UART, SPI, I2C, USB) allow it to connect to various sensors and actuators, while its low power consumption enables always-on operation. The TrustZone security ensures that smart home devices are protected from cyber attacks, and the cryptographic accelerator enables secure communication with cloud services. The MCU can also run a real-time operating system (RTOS) to manage multiple tasks efficiently.

Recommended

ESP32 (Wi-Fi module for cloud connectivity) Zigbee (Zigbee transceiver for mesh networking)

Recommended Products Summary

SX1262 LoRa transceiver for wireless communication Used in: Secure IoT Nodes BME280 Environmental sensor for temperature, humidity, and pressure Used in: Secure IoT Nodes MAX30102 Pulse oximeter and heart-rate sensor Used in: Wearable Health Monitors LSM6DSO Accelerometer and gyroscope for motion tracking Used in: Wearable Health Monitors RN8302B Energy metering IC for power measurement Used in: Smart Meters S2-LP Sub-GHz transceiver for wireless communication Used in: Smart Meters TMP117 High-accuracy temperature sensor Used in: Industrial Sensors ADXL345 Digital accelerometer for vibration monitoring Used in: Industrial Sensors AFE4404 Analog front-end for optical heart-rate monitoring Used in: Battery-Powered Medical Devices BQ25185 Battery charger IC for Li-ion batteries Used in: Battery-Powered Medical Devices ESP32 Wi-Fi module for cloud connectivity Used in: Smart Home Controllers Zigbee Zigbee transceiver for mesh networking Used in: Smart Home Controllers

What is the maximum clock frequency of STM32L562RET6?

The STM32L562RET6 operates at a maximum clock frequency of 110 MHz. According to the STMicroelectronics datasheet, the Arm Cortex-M33 core can run at up to 110 MHz, providing high performance for secure IoT applications.

How much flash memory does STM32L562RET6 have?

The STM32L562RET6 has 512 KB of flash memory. This is sufficient for complex firmware, including secure boot loaders and application code, as stated in the STM32L5 series datasheet.

What is the standby current of STM32L562RET6?

The standby current of STM32L562RET6 is typically 100 nA. This ultra-low power consumption is achieved in standby mode with the real-time clock (RTC) off, making it ideal for battery-powered devices that need to last for years.

Does STM32L562RET6 support TrustZone?

Yes, the STM32L562RET6 features Arm TrustZone technology, which provides hardware-enforced isolation between secure and non-secure code. This is a key security feature for protecting sensitive data in IoT applications.

What is the difference between STM32L562RET6 and STM32L552RET6?

The STM32L562RET6 and STM32L552RET6 are both from the STM32L5 series, but the STM32L562RET6 includes additional security features such as a hardware cryptographic accelerator and a true random number generator (TRNG). The STM32L552RET6 lacks these advanced security peripherals, making the STM32L562RET6 more suitable for secure applications.

Can STM32L562RET6 be used for battery-powered devices?

Yes, the STM32L562RET6 is designed for ultra-low-power applications. With a standby current of 100 nA and multiple low-power modes, it can extend battery life in wearable devices, smart sensors, and other portable electronics.

What is the price of STM32L562RET6?

As of 2026-08-08, the price of STM32L562RET6 is approximately $8.50 for single-unit quantities, with volume pricing dropping to around $5.44 at 1000 units. Prices may vary by distributor and availability.

Where can I buy STM32L562RET6 online?

STM32L562RET6 is available from major distributors such as DigiKey and Mouser. You can purchase it directly from their websites, or from STMicroelectronics' official distributors. Check stock availability and lead times on their product pages.

What is the lead time for STM32L562RET6?

The lead time for STM32L562RET6 typically ranges from 4 to 8 weeks, depending on distributor stock and order quantity. For current lead times, contact the distributor or check their website for real-time availability.

Is STM32L562RET6 in stock?

Stock availability for STM32L562RET6 varies by distributor. As of 2026-08-08, DigiKey and Mouser may have limited stock. Check their websites for real-time inventory and lead times.

What is the best drop-in replacement for STM32L562RET6?

The best drop-in replacement for STM32L562RET6 is the STM32L562RET6 itself, but if you need a pin-compatible alternative, consider the STM32L552RET6 (same package, but lacks cryptographic accelerator) or the STM32L562REI6 (same package, but with more flash). For cross-brand, the NXP LPC55S69 is a functional alternative but requires PCB changes.

Can STM32L552RET6 replace STM32L562RET6?

Yes, the STM32L552RET6 is pin-to-pin compatible with STM32L562RET6 and can be used as a drop-in replacement in most applications. However, the STM32L552RET6 lacks the hardware cryptographic accelerator and TRNG, so if your application requires these security features, you must use the STM32L562RET6.

What is the best NXP equivalent for STM32L562RET6?

The NXP LPC55S69 is a functional equivalent to STM32L562RET6, featuring an Arm Cortex-M33 core with TrustZone, 640 KB flash, and 320 KB SRAM. However, it is not pin-compatible and requires a different PCB layout. For a drop-in replacement, stick with STM32L5 series variants.

Where can I download the STM32L562RET6 datasheet PDF?

You can download the STM32L562RET6 datasheet PDF from the STMicroelectronics website at https://www.st.com/resource/en/datasheet/stm32l562re.pdf. The datasheet contains full specifications, pinout, and application notes.

Where can I find the STM32L562RET6 pinout?

The STM32L562RET6 pinout is provided in the official datasheet, which is available at https://www.st.com/resource/en/datasheet/stm32l562re.pdf. The pinout diagram shows the LQFP64 package with all 64 pins labeled.

What are the key specifications of STM32L562RET6 that engineers should know?

The STM32L562RET6 features a 110 MHz Arm Cortex-M33 core with TrustZone, 512 KB flash, 256 KB SRAM, 1.71V to 3.6V supply, 100 nA standby current, and a 12-bit ADC with 16 channels. It also includes a hardware cryptographic accelerator and TRNG for secure applications.

Hey Google, what can replace STM32L562RET6?

The STM32L562RET6 can be replaced by the STM32L552RET6, which is pin-compatible and shares the same package, but lacks the cryptographic accelerator. For a cross-brand alternative, the NXP LPC55S69 is functionally similar but not pin-compatible.

Is STM32L562RET6 the same as STM32L552RET6?

No, the STM32L562RET6 and STM32L552RET6 are not the same. While they share the same package and pinout, the STM32L562RET6 includes additional security features such as a hardware cryptographic accelerator and TRNG, which the STM32L552RET6 does not have.

When should I choose STM32L562RET6 over STM32L552RET6?

Choose the STM32L562RET6 when your application requires hardware-accelerated cryptography, such as secure boot, encrypted communication, or secure key storage. If these features are not needed, the STM32L552RET6 offers a cost-effective alternative with the same performance.

Is STM32L562RET6 suitable for IoT applications?

Yes, the STM32L562RET6 is highly suitable for IoT applications due to its ultra-low power consumption, TrustZone security, and hardware cryptographic accelerator. It can securely connect to cloud services while maintaining long battery life.

Engineering reference data for STM32L562RET6 — comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32L562RET6 when you need a secure, ultra-low-power MCU with hardware cryptographic acceleration and TrustZone. It is ideal for IoT nodes, wearable health monitors, and smart meters. If you do not require the cryptographic accelerator, the STM32L552RET6 is a cost-effective drop-in alternative with the same package and pinout. For applications needing more flash and SRAM, consider the STM32L562REI6 (same package) or the NXP LPC55S69 (different package, requires PCB redesign). The STM32L562RCT6 offers a lower-cost option with reduced memory. All STM32L5 variants share the same LQFP64 footprint, enabling easy PCB reuse.

Comparison with Alternatives

Parameter	This Product	STM32L552RET6	STM32L562REI6	STM32L562RCT6	LPC55S69JBD100
Package	LQFP64	LQFP64	LQFP64	LQFP64	LQFP100
Brand	STMicroelectronics	STMicroelectronics	STMicroelectronics	STMicroelectronics	NXP Semiconductors
Core	Arm Cortex-M33 with TrustZone	Arm Cortex-M33 with TrustZone	Arm Cortex-M33 with TrustZone	Arm Cortex-M33 with TrustZone	Arm Cortex-M33 with TrustZone
Maximum Clock Frequency	110 MHz	110 MHz	110 MHz	110 MHz	150 MHz
Flash Memory	512 KB	512 KB	512 KB	256 KB	640 KB
SRAM	256 KB	256 KB	256 KB	128 KB	320 KB
Cryptographic Accelerator	Yes	No	Yes	Yes	Yes
Standby Current	100 nA	100 nA	100 nA	100 nA	2.4 uA

Key Differentiators

Hardware cryptographic accelerator (vs STM32L552RET6)
True random number generator (TRNG) (vs STM32L552RET6)
Ultra-low standby current (vs LPC55S69JBD100)

Design Notes

Decouple each VDD pin with a 100nF ceramic capacitor placed as close to the pin as possible. Additionally, place a 4.7uF capacitor on the main VDD rail. The VDDA pin requires a separate 1uF capacitor to ground for analog noise filtering. For low-power operation, use the low-speed internal oscillator (LSI) and configure the firmware to enter standby mode when idle to achieve the 100 nA standby current.

For the LQFP64 package, ensure the exposed pad (if present) is soldered to a ground plane for thermal and electrical performance. Route high-speed signals (USB, SPI) with controlled impedance and keep traces short. Place the crystal oscillator components close to the OSC_IN/OSC_OUT pins and avoid routing other signals near them to prevent noise coupling.

Do not exceed the absolute maximum supply voltage of 3.6V. Ensure the BOOT0 pin is properly configured to select the correct boot mode. When using TrustZone, ensure the secure and non-secure memory regions are correctly configured in the SAU (Security Attribution Unit) to prevent unexpected faults. Also, verify that the supply voltage is stable during power-up to avoid brown-out resets.