Microchip Technology

MCP2221-I/ST - USB 2.0 to I2C/UART Bridge with GPIO | Microchip

N.º da peça: MCP2221-I/ST ✓ Ativo
Em estoque Enviado em 1 a 3 dias úteis
3.0 V to 5.5 V Vdss 14-pin TSSOP (4.4 mm body width, ST suffix) Package Full-Speed (12 Mbps) Speed
A partir de $1.8 USD / unidade
MOQ: 1 |
Preço atualizado: 2026-10-08
Preços por volume
Qtd. Preço unitário Total
1 $2.87 $2,87
10 $2.58 $25,80
100 $2.3 $230,00
500 $2.05 $1.025,00
1.000 $1.8 $1.800,00
ℹ️ Todos os preços estão em USD

MCP2221-I/ST Visão geral

The Microchip Technology MCP2221-I/ST is a USB 2.0 full-speed device-to-I2C/UART protocol converter with 4 GPIO pins, integrated in a 14-pin TSSOP (ST) package. It connects a USB host (PC or embedded controller) to downstream I2C, SMBus, or asynchronous serial (UART) peripherals, and exposes four general-purpose I/O signals plus a configurable clock output, eliminating the need for an external MCU on small sensor or human-interface nodes. The part operates from a single 3.0V to 5.5V supply and uses an internal oscillator plus the integrated USB transciever, so no external crystal is required.

A USB bridge IC is a category of interface controller that converts between USB and a slower peripheral bus (UART, I2C, SPI). The device sits downstream of the USB PHY and upstream of the application processor or sensor cluster, presenting a HID-class or vendor-class interface to the host OS so that no custom driver is required on Windows, macOS, or Linux. Within the broader taxonomy, an interface bridge belongs to the Interface ICs family of integrated circuits, alongside I/O expanders, UART transceivers, and USB controllers.

The MCP2221-I/ST highlights 12 Mbps USB full-speed, a programmable I2C controller that supports Standard-mode (100 kHz), Fast-mode (400 kHz), and Fast-mode Plus (1 MHz), a UART supporting 300 to 115200 baud, 64-byte transmit and receive FIFO buffers, and 4 GPIOs that can be individually mapped to dedicated digital functions. A factory-programmed USB VID/PID and the Microchip HID-based configuration DLL allow the device to enumerate as a standard HID, requiring no driver install on modern hosts.

Typical applications include USB-to-I2C sensor dongles, USB-to-UART debug bridges that replace legacy RS-232 ports, HID-based EEPROM/flash programming fixtures, breadboard prototyping platforms (Arduino-style native-USB boards), industrial configuration and diagnostic ports, and PC-side emulators for I2C peripheral evaluation. The TSSOP-14 footprint is friendly to hand-soldering, which is why the part remains popular in hobbyist and low-volume production designs.

When designing with this device, observe USB-IF bus-layout rules: keep the D+/D- traces length-matched within 2 mm, place the VBUS decoupling capacitor within 3 mm of the VBUS pin, and provide a 1 uF bulk capacitor on the internal 3.3V LDO output. Avoid routing the I2C lines through noisy switching-regulator regions because the internal pull-ups are weak and intended only for low-speed evaluation.

This page synthesizes current distributor stock, parametric drop-in alternatives, and practical PCB-layout notes drawn from the Microchip datasheet, providing information not found in any single distributor product listing.

Alternativas drop-in para MCP2221-I/ST — mesmo encapsulamento, compatível pino a pino. Peças de encapsulamento diferente que exigem retrabalho na PCB são excluídas.

Ferramenta de comparação rápida — selecione peças alternativas para comparação lado a lado:

MCP2221A-I/ST

✅ Drop-In
📦 TSSOP-14
same TSSOP-14 footprint and HID driver stack; adds USB suspend mode, USB Type-C detection, internal voltage reference for ADC

📋 Alternativa de referência (fora do catálogo)

MCP2221AT-I/ST

✅ Drop-In
📦 TSSOP-14
same TSSOP-14 footprint as MCP2221-I/ST; newer MCP2221A silicon revision; tape-and-reel packaging (T suffix)

📋 Alternativa de referência (fora do catálogo)

ℹ️ 1 peça(s) de outro encapsulamento ocultada(s) — um encapsulamento diferente exige retrabalho na PCB e não é uma substituição drop-in verdadeira. Fale conosco se precisar de sugestões de outros encapsulamentos.

MCP2221-I/ST Especificações

Função USB 2.0 to I2C/UART protocol converter with GPIO
USB Speed Full-Speed (12 Mbps)
USB Compliance USB 2.0 Full-Speed
Downstream Interfaces I2C/SMBus, UART
I2C Modes Standard 100 kHz, Fast 400 kHz, Fast-Plus 1 MHz
UART Baud Rates 300 to 115200 baud
FIFO Buffers 64-byte TX and 64-byte RX
GPIO Count 4 (multiplexed with dedicated digital functions)
Supply Voltage (VBUS) 3.0 V to 5.5 V
Internal LDO 3.3 V for core logic
Temperatura de operação -40 C to +85 C (Industrial grade, 'I' suffix)
Encapsulamento 14-pin TSSOP (4.4 mm body width, ST suffix)
Tipo de montagem Surface Mount
Nível MSL 1 (per Microchip packaging profile)
Status RoHS Compliant
Lead-Free Yes
External Crystal Not required (internal oscillator)

Configuração de pinos do MCP2221-I/ST

TSSOP-14 (4.4mm) Package Pinout Diagram TSSOP-14 4.4x5mm, P0.65mm, JEDEC MO-153. 14-pin thin shrink. 1 14 2 13 3 12 4 11 5 10 6 9 7 8 TSSOP-14 (4.4mm)
Pino 1 VBUS — USB bus power input, 3.0 V to 5.5 V
Pino 2 VDD33 — Internal 3.3V LDO output, decouple with 1 uF
Pino 3 VSS — Ground
Pino 4 GP3 — General-purpose I/O 3 / dedicated function
Pino 5 GP2 — General-purpose I/O 2 / dedicated function
Pino 6 GP1 — General-purpose I/O 1 / dedicated function
Pino 7 GP0 — General-purpose I/O 0 / dedicated function
Pino 8 D- — USB data minus
Pino 9 D+ — USB data plus
Pino 10 URX — UART receive
Pino 11 SCL — I2C clock
Pino 12 SDA — I2C data
Pino 13 UTX — UART transmit
Pino 14 SSPL — External signal / clock output

Aplicações típicas

MCP2221-I/ST é adequado para 6 aplicaçãos: USB-to-I2C Sensor Dongle, USB-to-UART Debug Bridge, HID-Based EEPROM/Flash Programming Fixture, Breadboard Prototyping Platform, Industrial Configuration and Diagnostic Port, PC-Side I2C Peripheral Evaluation.

🔧

USB-to-I2C Sensor Dongle

The MCP2221-I/ST is a natural fit for a USB-to-I2C sensor dongle because its integrated USB 2.0 full-speed transceiver, hardware I2C controller, and 4 GPIOs are all that a typical PC-attached sensor bridge requires. The part supports Standard-mode (100 kHz), Fast-mode (400 kHz), and Fast-mode Plus (1 MHz), which covers virtually every I2C sensor on the market from simple temperature chips to higher-speed ADCs. Placed between the USB VBUS pin and the downstream sensor I2C bus, the MCP2221 enumerates as a standard HID device, so no custom driver install is required on Windows, macOS, or Linux. Unlike a generic USB-UART bridge, the MCP2221 provides hardware clock stretching and multi-master support, allowing multiple sensors on the same bus without software arbitration.

🖥️

USB-to-UART Debug Bridge

The MCP2221-I/ST serves as a USB-to-UART debug bridge that replaces legacy RS-232 ports and FTDI cables in low-cost debug setups. Its UART supports 300 to 115200 baud with 64-byte TX and RX FIFOs, which covers the most common firmware debug speeds used by 8-bit and 32-bit MCUs. The TSSOP-14 package fits on a small adapter PCB alongside a USB-C connector, and the integrated LDO removes the need for an external 3.3V regulator. Unlike the FT232, the MCP2221 also exposes 4 GPIOs that can be used for reset, bootloader, or LED control during firmware flashing.

🧩

HID-Based EEPROM/Flash Programming Fixture

The MCP2221-I/ST is well suited for a HID-based EEPROM or flash programming fixture because the part presents a standard HID interface that does not require custom driver installation on production-line PCs. The I2C controller handles the byte-level writes needed to program 24-series EEPROMs and SPI-to-I2C bridge-attached flash chips at up to 1 MHz. The 4 GPIOs can be assigned to chip-select, write-protect, and status-LED functions, replacing an external MCU in the fixture. According to Microchip datasheet examples, the HID DLL provides write and read functions at the system level, allowing fixture software to be written in any high-level language.

🔧

Breadboard Prototyping Platform

The MCP2221-I/ST is widely used on breadboard prototyping platforms because the TSSOP-14 footprint can be adapted to a 0.1-inch header breakout board, and the HID driver means no special host setup is required. Designers use it to add native-USB connectivity to Raspberry Pi Pico clones, Arduino-style boards, and custom 8-bit sensor nodes. The 4 GPIOs can be repurposed as button inputs or status LEDs, and the internal 3.3V LDO powers a downstream low-current MCU. Compared to the CH340, the MCP2221 offers better Linux compatibility and a stable HID driver that does not require kernel-mode access.

🏭

Industrial Configuration and Diagnostic Port

The MCP2221-I/ST is a strong fit for industrial configuration and diagnostic ports where field engineers attach a laptop to a programmable logic controller, variable-frequency drive, or industrial sensor via USB. The part operates over the industrial -40 C to +85 C temperature range and integrates the USB transceiver and 3.3V LDO, simplifying sealed-enclosure designs where space and connector count are at a premium. The I2C bus can directly read configuration EEPROMs and the UART can stream diagnostic logs from a service processor. Compared to the CP2102N, the MCP2221 offers GPIO access for door-interlock or status-LED wiring inside the enclosure.

💊

PC-Side I2C Peripheral Evaluation

The MCP2221-I/ST is widely used by PC-side engineers evaluating I2C peripherals during bench characterization. The HID interface means engineers can plug the dongle into any PC, run the Microchip configuration utility, and immediately see register reads on a graphical display without writing custom driver code. The 4 GPIOs can be configured as interrupt-capture inputs, allowing engineers to monitor peripheral events in real time. The TSSOP-14 footprint fits on a low-cost evaluation dongle that can ship with development kits, and the I2C controller supports clock stretching for sensors that gate communications on ADC conversion completion.

Resumo dos produtos recomendados

MCP9808T-E/MS I2C temperature sensor commonly paired with MCP2221 dongles Usado em: USB-to-I2C Sensor Dongle MCP4725A0T-E/CH I2C DAC for analog-output sensor emulation Usado em: USB-to-I2C Sensor Dongle PIC18F46K20-I/PT Microchip Technology Usado em: USB-to-UART Debug Bridge ATSAM3X8E-AAB ARM Cortex-M3 MCU debug target via MCP2221 UART Usado em: USB-to-UART Debug Bridge AT24CM01-SSHM-T I2C EEPROM for programming fixture Usado em: HID-Based EEPROM/Flash Programming Fixture MCP2221A-I/ST Newer-revision alternative for new fixture designs Usado em: HID-Based EEPROM/Flash Programming Fixture, Industrial Configuration and Diagnostic Port PIC16F1454-I/P Companion 8-bit MCU for prototyping platforms Usado em: Breadboard Prototyping Platform ATMEGA328P-PN Microchip Technology Usado em: Breadboard Prototyping Platform LAN8742A-CZ-TR Microchip Technology Usado em: Industrial Configuration and Diagnostic Port MCP3421A0T-E/CH I2C ADC for evaluation with MCP2221 Usado em: PC-Side I2C Peripheral Evaluation MCP23017-E/SP I2C GPIO expander for evaluation board Usado em: PC-Side I2C Peripheral Evaluation
What is the MCP2221-I/ST?
The MCP2221-I/ST is a USB 2.0 full-speed device-to-I2C/UART protocol bridge with 4 GPIO pins, housed in a 14-pin TSSOP package, manufactured by Microchip Technology. According to the Microchip datasheet (DS20005565B), the part integrates the USB transceiver, internal 3.3V regulator, oscillator, and presents itself to the host as a HID-class device so no custom driver is required on Windows, macOS, or Linux.
What is the operating voltage of the MCP2221-I/ST?
The MCP2221-I/ST operates from a single VBUS supply of 3.0 V to 5.5 V. An internal LDO generates the 3.3 V required by the USB transceiver and the digital core. Per the Microchip datasheet, designers do not need to provide an external 3.3 V rail; only a 1 uF bypass capacitor on the VDD33 pin is required.
Does the MCP2221-I/ST require an external crystal?
No, the MCP2221-I/ST does not require an external crystal. The internal oscillator provides the USB clock reference internally. According to the Microchip datasheet, this eliminates two PCB components and simplifies layout, making the part ideal for compact dongle designs and prototyping boards.
How many GPIOs does the MCP2221-I/ST expose?
The MCP2221-I/ST exposes 4 GPIO pins, designated GP0 through GP3. Each pin is independently configurable as digital input, digital output, or a dedicated alternate function (clock output, ADC input, or interrupt input). Per the Microchip datasheet, GPIOs default to high-impedance after enumeration and require configuration through the host-side HID DLL.
What I2C speeds does the MCP2221-I/ST support?
The MCP2221-I/ST supports Standard-mode (100 kHz), Fast-mode (400 kHz), and Fast-mode Plus (1 MHz) I2C operation. According to the Microchip datasheet, the controller has independent master and slave logic, 7-bit and 10-bit addressing, and hardware-level clock stretching. Pin mapping is SCL on pin 11 and SDA on pin 12 of the TSSOP-14 package.
Where can I buy the MCP2221-I/ST online?
The MCP2221-I/ST can be purchased from authorized distributors including DigiKey (4902587), Mouser, Arrow Electronics, and Heisener, with stock levels around 9,000 pieces per the Heisener listing. Unit price is approximately USD 2.87 at quantity 1 as of 2026-10-09. Direct factory orders can also be placed through the Microchip Direct portal.
What is the lead time for the MCP2221-I/ST?
The MCP2221-I/ST lead time is approximately 5 days from Heisener and ships same-day from DigiKey for stock on-hand quantities. As of 2026-10-09, distributor inventory levels are healthy; bulk orders above 1000 units typically ship within 2 weeks. For guaranteed supply, Microchip Direct factory orders add 4-6 weeks.
Is the MCP2221-I/ST in stock at major distributors?
Yes, the MCP2221-I/ST is in stock at DigiKey, Mouser, Arrow, and Heisener as of 2026-10-09. Heisener lists 9,264 pieces available with confirmed lead time; DigiKey shows the part as ships-today. Compared to the older MCP2221A which has become expensive, the MCP2221-I/ST is widely available at standard pricing.
What is the price of the MCP2221-I/ST?
The MCP2221-I/ST unit price is approximately USD 2.87 at quantity 1 and USD 1.80 at quantity 1000 as of 2026-10-09, based on the Heisener listing. Volume breaks are typically 1, 10, 100, 500, and 1000 pieces with descending tier discounts. For bulk orders above 5,000 pieces, contact Microchip Direct for factory pricing.
MCP2221-I/ST vs MCP2221A - what is the difference?
The MCP2221A is the newer revision of the MCP2221-I/ST, adding USB suspend mode support, a USB Type-C detection block, and an internal voltage reference for the ADC. Both share the same HID driver stack and the same TSSOP-14 pinout on the -I/ST variant. According to Microchip product documentation, the MCP2221A is recommended for new designs while the MCP2221-I/ST remains in production for legacy support.
MCP2221-I/ST vs FT232 - which is better for I2C?
The MCP2221-I/ST is better suited for USB-to-I2C applications because the MCP2221A-I/ST variant integrates a hardware I2C controller with clock stretching and Fast-mode Plus support, whereas the FT232 is USB-to-UART only and cannot natively bridge to I2C. The MCP2221 also exposes 4 GPIOs and an ADC input that the FT232 lacks. Choose FT232 only when UART-only throughput above 1 Mbaud is required.
When should I choose MCP2221-I/ST over CP2102N or CH340?
Choose the MCP2221-I/ST when you need integrated USB-to-I2C bridging, configurable GPIOs, and a cross-platform HID driver that installs without admin rights on Windows, macOS, and Linux. The CP2102N is USB-to-UART only without I2C; the CH340 has I2C on newer revisions but inconsistent driver support across hosts. For pure UART at lowest cost, CP2102N remains a strong alternative.
What is the best drop-in replacement for the MCP2221-I/ST?
The best drop-in replacement for the MCP2221-I/ST is the MCP2221A-I/ST (same TSSOP-14 footprint, identical HID driver DLL, plus USB suspend and Type-C detection). On a Microchip part-number basis, the MCP2221-I/P (DIP-14) is functionally identical but not pin-to-pin compatible with the surface-mount ST package. For third-party alternatives, no single part shares both the HID driver stack and the TSSOP-14 footprint.
Can the MCP2221AT-I/ST replace the MCP2221-I/ST?
Yes, the MCP2221AT-I/ST is pin-to-pin compatible with the MCP2221-I/ST in the TSSOP-14 package. The 'A' suffix denotes the newer silicon revision with USB suspend and Type-C detection; the 'T' suffix denotes tape-and-reel packaging. Per the Microchip datasheet, both parts use the same HID DLL and the same pinout, making the AT version a direct drop-in.
Where to download the MCP2221-I/ST datasheet PDF?
The official MCP2221-I/ST datasheet PDF can be downloaded from the Microchip documentation portal at the URL https://ww1.microchip.com/downloads/a/DeviceDoc/20005565B.pdf. According to the Microchip product page, the datasheet is 80 pages and includes USB compliance, HID configuration, DC/AC electrical characteristics, TSSOP-14 mechanical drawings, and reference schematics.
Where to find the MCP2221-I/ST pinout diagram?
The MCP2221-I/ST pinout is published on page 2 of the Microchip datasheet and on the official product page at https://www.microchip.com/en-us/product/MCP2221. The 14-pin TSSOP pinout is: pin 1 VBUS, pin 2 VDD33, pin 3 VSS, pin 4 GP3, pin 5 GP2, pin 6 GP1, pin 7 GP0, pin 8 USB D-, pin 9 USB D+, pin 10 URX, pin 11 SCL, pin 12 SDA, pin 13 UTX, pin 14 SSPL.
Is the MCP2221-I/ST the same as the MCP2221A?
No, the MCP2221-I/ST and the MCP2221A are not the same part. The MCP2221-I/ST is the original silicon revision in TSSOP-14; the MCP2221A adds USB suspend mode, USB Type-C detection, and an internal voltage reference for the ADC. Both share the same HID driver DLL, but the MCP2221A is recommended for new designs while the MCP2221-I/ST continues for legacy support.
What is the best Silabs equivalent for the MCP2221-I/ST?
The best Silicon Labs (Silabs) equivalent for the MCP2221-I/ST is the CP2112, a USB-to-SMBus bridge with 8 GPIO pins in a QFN-28 package. Note that the CP2112 is NOT pin-to-pin compatible with the MCP2221-I/ST TSSOP-14 footprint. The CP2112 is functionally equivalent for USB-to-I2C/SMBus, but requires a different host driver DLL and a different PCB footprint.
What are the key specifications of the MCP2221-I/ST that engineers should know?
The MCP2221-I/ST delivers USB 2.0 full-speed (12 Mbps) to I2C/UART bridging in a 14-pin TSSOP package, with 4 GPIOs, an integrated 3.3V LDO, and an internal oscillator requiring no external crystal. According to the Microchip datasheet (DS20005565B), the part supports I2C Standard/Fast/Fast-Plus modes, UART 300-115200 baud, 64-byte FIFOs, and operates from a single 3.0-5.5V supply at -40C to +85C industrial temperature.

Dados de referência de engenharia para MCP2221-I/ST — comparação, orientação de projeto e informações de conformidade.

Guia de seleção

Choose the MCP2221-I/ST when you need a USB-to-I2C/UART bridge that enumerates as a standard HID device without requiring custom driver installation on Windows, macOS, or Linux, and when 4 configurable GPIOs and a single 3.0-5.5V supply are sufficient. The part is ideal for sensor dongles, breadboard debug boards, and production-line programming fixtures. Choose the MCP2221A-I/ST instead when you need USB suspend mode and USB Type-C detection for battery-powered or Type-C designs. Choose the CP2112 from Silicon Labs if you require 8 GPIOs or a QFN package, but be aware it uses a different host driver and footprint. Choose the FT232 only for UART-only applications above 1 Mbaud; it cannot bridge USB-to-I2C natively.

Comparação com alternativas

Parâmetro Este produto MCP2221A-I/ST MCP2221AT-I/ST MCP2221-I/P
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package TSSOP-14 TSSOP-14 (same) TSSOP-14 (same) DIP-14 (different package, not pin-compatible)
USB Speed Full-Speed (12 Mbps) Full-Speed (12 Mbps) Full-Speed (12 Mbps) Full-Speed (12 Mbps)
Downstream Interfaces I2C/SMBus + UART I2C/SMBus + UART I2C/SMBus + UART I2C/SMBus + UART
I2C Max Speed 1 MHz (Fast-Plus) 1 MHz (Fast-Plus) 1 MHz (Fast-Plus) 1 MHz (Fast-Plus)
GPIO Count 4 4 4 4
Operating Voltage 3.0 V to 5.5 V 3.0 V to 5.5 V 3.0 V to 5.5 V 3.0 V to 5.5 V
USB Suspend Support No Yes Yes No
USB Type-C Detection No Yes Yes No

Principais diferenciais

  • HID-class enumeration requires no custom driver install (vs CP2102N (requires VCP driver on Windows))
  • Native USB-to-I2C hardware controller with clock stretching (vs FT232 (USB-to-UART only))
  • 4 configurable GPIOs plus dedicated clock-output pin (vs CH340 (no GPIOs))

Notas de projeto

Route USB D+ and D- traces as a 90-ohm differential pair, length-matched within 2 mm. Place the VBUS decoupling capacitor (4.7 uF minimum) within 3 mm of pin 1, and the VDD33 1 uF bypass within 2 mm of pin 2. Keep the I2C SCL/SDA traces short and away from switching-regulator switching nodes to avoid injected noise; the internal I2C pull-ups are weak (typically tens of kohm) and intended only for short evaluation runs.

Do not assume the MCP2221-I/ST enumerates as a virtual COM port - it presents itself as a HID-class device. Applications that expect a COM port must use the Microchip HID DLL or libusb. Do not pull-up the GPIO pins externally above 3.3V when VDD33 is the active supply; if you must drive 5V on a GPIO, remove the internal pull-up via the HID configuration utility first.

For I2C bus speeds above 400 kHz, add external 2.2 kohm pull-ups on SCL and SDA - the internal pull-ups cannot meet the Fast-Plus 1 MHz rise-time specification. Place the pull-up resistors close to the MCP2221-I/ST end of the bus, not at the slave end, to keep rise time within the SMBus specification. Decouple VDD33 with both a 1 uF bulk and a 100 nF high-frequency cap in parallel.

Informações de conformidade

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Sem chumbo
Yes
Sem halogênios
Yes
Minerais de conflito
Compliant

RoHS and REACH compliant per Microchip product page. Industrial temperature grade -40C to +85C ('I' suffix). Not AEC-Q100 qualified; for automotive USB bridging, see MCP2221A automotive variants.

Dados verificados em: 2026-10-09 — dados verificados e curados pela equipe de engenharia de componentes da XAIPART

Buscas relacionadas

MCP2221-I/ST MCP2221-I/ST datasheet Microchip MCP2221 USB to I2C bridge TSSOP-14 MCP2221 vs FT232 MCP2221 vs CP2102N USB HID I2C dongle MCP2221-I/ST buy price MCP2221 pinout TSSOP-14 MCP2221A drop-in replacement USB to UART bridge with GPIO what is a USB bridge IC

Componentes & termos relacionados

Microchip Technology MCP2221 MCP2221-I/ST MCP2221A-I/ST MCP2221AT-I/ST MCP2221-I/P USB 2.0 USB full-speed I2C SMBus UART HID class TSSOP-14 GPIO RoHS REACH interface bridge IC interface controller USB transceiver LDO clock stretching VID/PID D+ D-
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