Microchip Technology

ATSAM4E16EB-AN - 120MHz Cortex-M4 MCU 1MB Flash | Microchip

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1.2 V / 3.3 V Vdss 144-LQFP (20 x 20 mm) Package 120 MHz Speed 1 MB (1M x 8) Memory
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Price updated: 2026-09-19
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1,000 $8.2 $8,200.00
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ATSAM4E16EB-AN Overview

The Microchip Technology ATSAM4E16EB-AN is a 32-bit ARM Cortex-M4 microcontroller running at 120 MHz with 1 MB embedded Flash and a 144-pin LQFP (20x20 mm) package. It integrates a floating point unit (FPU), 117 general-purpose I/O lines, and a rich connectivity set including Ethernet MAC, CAN bus, USB, SPI, UART/USART, IrDA, SD/SDIO, and EBI/EMI external bus interface.

A microcontroller (MCU) is a single integrated circuit that combines a processor core, memory, and programmable peripherals into one chip, sitting at the heart of embedded systems from industrial automation to consumer devices. The SAM4E series belongs to Microchip's (formerly Atmel) 32-bit SAM ARM flash MCU family, positioned above the SAM3 and SAM4N series where high bandwidth, Ethernet, and math-intensive processing are required.

Key differentiating features include the 120 MHz Cortex-M4 core with hardware FPU for single-precision math, a high data bandwidth bus architecture, integrated 10/100 Ethernet MAC, dual CAN 2.0B controllers, a 12-bit ADC, PWM channels, DMA, and safety peripherals such as brown-out detect, power-on reset, and a watchdog timer. This combination suits networked and control-oriented designs that would otherwise require multiple chips.

Technically, the device operates from a 1.2V/3.3V supply scheme (3.3V main, 1.2V core regulation) and is offered in extended temperature, green/RoHS packaging. The Flash-based program memory supports in-system programming, and the external bus interface allows glueless attachment of SRAM, NOR Flash, and LCD modules.

Typical applications include industrial Ethernet gateways, motor control and solar inverter systems, building automation nodes, and embedded networking equipment where CAN, Ethernet, and USB must coexist on one 120 MHz controller.

Design consideration: the LQFP-144 is a fine-pitch (0.5 mm) surface-mount package - plan 4-layer PCB stackups and verify Ethernet PHY magnetics placement early; pinout planning against the 117 I/O budget is essential before routing.

This page synthesizes distributor pricing, stock data, drop-in family alternatives, and practical design notes not consolidated in the manufacturer datasheet, as of 2026-09-20.

Drop-in alternatives for ATSAM4E16EB-AN — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAM4E16EB-AN (same form factor and footprint) — differing in Package, RoHS Status, FPU, Floating Point Unit, Product Series.

Microchip Technology
Package: 144-LQFP (20x20 mm)
FPU: Yes (Cortex-M4 FPU)
Product Series: SAM4E (ATSAM4E16E)
Compare with ATSAM4E16EB-AN →
Microchip Technology
Package: 144-LFBGA (10 x 10 mm)
RoHS Status: Compliant (green package)
Floating Point Unit: Yes (single precision)
Compare with ATSAM4E16EB-AN →
Microchip Technology
RoHS Status: Compliant (green package)
Floating Point Unit: Yes (single precision FPU)
Product Series: SAM4E (Atmel | SMART)
Compare with ATSAM4E16EB-AN →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAM4E16EA-AN

✅ Drop-In
📦 144-LQFP (20x20)
die revision EA vs EB; identical 1 MB Flash, 120 MHz Cortex-M4, pinout and package

📋 Reference alternative (not in catalog)

ATSAM4E16EB-CN

✅ Drop-In
Microchip Technology
📦 144-LQFP (20x20)
ARM Cortex-M4 · 32-Bit · 120 MHz · 1 MB (1M x 8) · Yes (single precision) · Full-Speed USB · Dual ADC / DAC · 1.2 V / 3.3 V

✓ In Stock

$6.05 / Unit

View Datasheet →

ATSAM4E16EB-AN Maximum Ratings & Electrical Characteristics

Core Processor ARM Cortex-M4
Core Size 32-bit
Core Frequency 120 MHz
Flash Memory 1 MB (1M x 8)
Series SAM4E
FPU Yes (single precision)
Connectivity CANbus, EBI/EMI, Ethernet, IrDA, SD, SPI, UART/USART, USB
Peripherals Brown-out Detect/Reset, DMA, POR, PWM, WDT
Number of I/O 117
ADC Resolution 12-bit
Supply Voltage 1.2 V / 3.3 V
Package 144-LQFP (20 x 20 mm)
Mounting Type Surface Mount
Temperature Grade Extended temp (EXT TEMP, per Mouser listing)
Part Status Active
Packing Tray (MRL, green)
RoHS Status Green / RoHS compliant (per Mouser LQFP,GREEN listing)

ATSAM4E16EB-AN 144-lqfp (20 x 20 mm) Pin Configuration Guide

Pin configuration for ATSAM4E16EB-AN (144-lqfp (20 x 20 mm) package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

144-lqfp (20 x 20 mm) package pinout diagram for ATSAM4E16EB-AN

No detailed pinout data available for ATSAM4E16EB-AN.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4E16EB-AN is suitable for 6 applications: Industrial Ethernet Gateways, Motor Control and Solar Inverters, Building Automation Nodes, Embedded Networking Equipment, HMI and Display Controllers, Data Acquisition and Test Instrumentation.

🏭

Industrial Ethernet Gateways

The ATSAM4E16EB-AN fits industrial Ethernet gateways because it integrates a 10/100 Ethernet MAC, dual CAN 2.0B controllers, and multiple UART/USART ports on a single 120 MHz Cortex-M4 core with FPU. Protocol translation between factory CANbus networks and Ethernet-based supervisory systems is handled without external communication chips, while the 1 MB Flash holds protocol stacks for EtherCAT-adjacent tooling, Modbus TCP, and web servers simultaneously. The DMA controller offloads peripheral transfers so the CPU bandwidth remains available for protocol processing at line rate. With 117 GPIO and the EBI external bus interface, the same chip drives status displays and expansion modules. Operating at 3.3 V with extended temperature grading, it mounts directly on DIN-rail controller boards, and the watchdog plus brown-out reset provide the fault recovery behavior expected in continuously powered industrial installations.

Motor Control and Solar Inverters

The SAM4E16E is positioned by Microchip for motor control and solar inverter applications, and the ATSAM4E16EB-AN's hardware floating point unit executes the single-precision trigonometry behind field-oriented control (FOC) at 120 MHz without software math libraries. The 12-bit ADC samples phase currents synchronized to PWM updates via the peripheral DMA, minimizing CPU jitter in the control loop. Complementary PWM outputs drive three-phase inverter bridges, while the CAN interface links the drive to industrial or vehicle networks for supervisory commands. The 1 MB Flash stores sensorless algorithms, parameter tables, and commissioning diagnostics in one image. Brown-out detection and the watchdog timer ensure safe PWM shutdown during supply anomalies - a critical safety property in high-power conversion stages. The 144-pin LQFP also provides enough I/O to supervise gate-driver fault lines, encoder inputs, and Housekeeping signals on the same die.

🏢

Building Automation Nodes

Building automation controllers require networked, low-maintenance, always-on operation, and the ATSAM4E16EB-AN delivers this profile: the Ethernet MAC supports BACnet/IP and web-based management, CAN connectivity interoperates with legacy楼宇 buses, and 117 GPIO lines handle relay banks, sensor inputs, and local keypads on one chip. The 120 MHz Cortex-M4 with FPU executes control loops for HVAC actuators while simultaneously serving the network stack, with DMA keeping ADC and UART streams moving without CPU polling. Extended temperature qualification allows installation in rooftop units and mechanical rooms where ambient temperatures exceed commercial limits. The 1 MB Flash accommodates over-the-air firmware staging for field updates, a common requirement in large building estates. Its green/RoHS LQFP-144 packaging also simplifies compliance documentation for large-volume construction projects requiring environmental declarations from every component supplier.

🌐

Embedded Networking Equipment

For compact networking equipment such as managed sensor hubs, serial-to-Ethernet converters, and access-control panels, the ATSAM4E16EB-AN consolidates the needed connectivity - Ethernet, USB device, dual CAN, four-plus UART/USART channels, SPI, and SD card interface - onto one 120 MHz controller. The EBI/EMI external bus interface attaches SRAM or NOR Flash for packet buffering beyond on-chip RAM, a capability few MCUs in this class retain. The USB peripheral supports device-class firmware for configuration tools, while the SD interface logs events to removable media. Hardware DMA on all major peripherals sustains throughput with low CPU load, and the FPU accelerates TLS-adjacent crypto pre-processing. Running at 3.3 V in a 20x20 mm LQFP-144, the design footprint stays compact, and Microchip's active lifecycle status ensures long-term sourcing for products with multi-year service commitments.

📺

HMI and Display Controllers

The EBI/EMI interface of the ATSAM4E16EB-AN attaches LCD modules and graphics memory gluelessly, making it a strong HMI controller: the 120 MHz Cortex-M4 with FPU renders UI elements, touch filtering, and communications concurrently. The 1 MB Flash holds fonts, bitmap assets, and localization tables for multilingual panels, while 117 GPIO lines drive backlight PWM, beeper outputs, and a resistive-touch divider network through its 12-bit ADC. CAN and Ethernet links let the same panel talk to both PLC-level networks and plant IT systems, consolidating what traditionally required two processors. PWM channels provide dimmable backlight control with hardware timebases, keeping brightness stable regardless of CPU load. For industrial panels exposed to temperature extremes, the extended-temp, green LQFP-144 package survives the environment while remaining hand-assemblable with standard hot-bar or reflow equipment used in HMI volume production.

🔧

Data Acquisition and Test Instrumentation

Benchtop and rack data-acquisition modules benefit from the ATSAM4E16EB-AN's 12-bit ADC, DMA-driven sampling, USB and Ethernet streaming, and the precision timing available from its timer/counter peripherals at 120 MHz. The FPU performs calibration math - polynomial linearization, RMS computation, FFT windows - in-line without a separate DSP. The EBI interface captures data from external high-speed ADC front-ends or pattern-generator FIFOs through the external bus at memory-like speeds, while 1 MB Flash retains calibration tables and self-test firmware across power cycles. Dual CAN ports connect instruments to vehicle or industrial test networks, useful in HIL test racks. With 117 GPIO available for relay multiplexers, range-switching, and indicator control, a complete 32-channel acquisition channel-select system can be run from this single controller, reducing BOM count and calibration drift points relative to multi-chip designs.

Recommended Products Summary

KSZ8081RNA Ethernet PHY for the SAM4E integrated MAC Used in: Industrial Ethernet Gateways MCP2515 Additional CAN channel expansion Used in: Industrial Ethernet Gateways MCP16301 Buck regulator for 3.3V controller supply Used in: Motor Control and Solar Inverters MCP9808 Temperature sensor for heatsink monitoring Used in: Motor Control and Solar Inverters ATA6563 CAN transceiver for bus networks Used in: Building Automation Nodes MCP79410 Battery-backed RTC for scheduling Used in: Building Automation Nodes KSZ8851SNL Second Ethernet port via SPI Used in: Embedded Networking Equipment MCP2200 USB-to-UART configuration bridge Used in: Embedded Networking Equipment MCP4131 Digital potentiometer for backlight calibration Used in: HMI and Display Controllers MCP23S17 SPI GPIO expander for keypad matrix Used in: HMI and Display Controllers MCP3421 18-bit delta-sigma ADC for precision channels Used in: Data Acquisition and Test Instrumentation MCP4725 DAC for stimulus/signal generation Used in: Data Acquisition and Test Instrumentation
What is the ATSAM4E16EB-AN microcontroller?
The ATSAM4E16EB-AN is a Microchip Technology 32-bit ARM Cortex-M4 microcontroller from the SAM4E series running at 120 MHz with 1 MB of embedded Flash memory. Per DigiKey's listing, it comes in a 144-pin LQFP (20x20 mm) package with 117 I/O pins and connectivity including Ethernet, CANbus, USB, SPI, UART/USART, SD, IrDA, and an external bus interface (EBI/EMI). It integrates a floating point unit, DMA, PWM, and watchdog peripherals for networked industrial control applications.
What are the key specifications of ATSAM4E16EB-AN engineers should know?
The key specifications are: ARM Cortex-M4 32-bit core at 120 MHz with FPU, 1 MB Flash, 144-LQFP package (20x20 mm), 117 GPIO, 12-bit ADC, Ethernet MAC, dual CAN support, USB, SPI, UART/USART, SD interface, EBI/EMI external memory bus, and peripherals including DMA, PWM, brown-out detect, POR and watchdog timer. Supply levels are 1.2 V core and 3.3 V I/O per JAK Electronics' comparison data. The part is active, extended temperature, and green/RoHS packed in trays.
What is the price of ATSAM4E16EB-AN?
As of 2026-09-20, distributor pricing for ATSAM4E16EB-AN varies by channel: Heisener lists a unit price of $12.5845 (USD) with 3,584 pieces in stock, while LCSC offers the part from $4.6236 in stock. Volume breaks typically reduce unit cost further; XAIPART lists tiered pricing at 1/10/100/500/1000 piece quantities. Because MCU pricing fluctuates with supply conditions, request a quotation for current volume pricing.
Where to buy ATSAM4E16EB-AN online?
ATSAM4E16EB-AN can be purchased from DigiKey (ships today per their listing), Mouser, LCSC, Heisener (3,584 units in stock as of 2026-09-20), Octopart-listed distributors, and Microchip USA for excess inventory. XAIPART also offers this part with tiered pricing and quotation support. DigiKey's product page confirms buy-now availability, while independent distributors like Heisener and Microchip USA are useful when authorized stock is constrained.
Is ATSAM4E16EB-AN in stock?
Yes, ATSAM4E16EB-AN is in stock at multiple distributors as of 2026-09-20: Heisener reports 3,584 pieces available and LCSC lists stock with pricing from $4.6236. DigiKey states 'buy now, ships today' on its product page. Lead time on some channels is listed as 'to be confirmed' (Heisener), so for production volumes, request formal lead-time confirmation from your chosen distributor before scheduling builds.
Where can I download the ATSAM4E16EB-AN datasheet PDF?
The official ATSAM4E16EB-AN documentation is available on Microchip's product page for the ATSAM4E16E family at microchip.com. Datasheet PDFs are also mirrored on Octopart's datasheet section and distributor pages such as DigiKey, Mouser, and LCSC. According to FindMyChip, the official Microchip datasheet contains full specifications including pin configuration, electrical characteristics, and application notes - always prefer the manufacturer's latest revision over third-party copies.
What is the difference between ATSAM4E16EB-AN and ATSAM4E16EA-AN?
Both are SAM4E series 32-bit ARM Cortex-M4 microcontrollers with 1024 KB Flash in a 144-pin LQFP operating from 1.2 V/3.3 V supplies, per JAK Electronics' comparison data. The EA and EB suffixes denote minor die revisions within the same SAM4E16E family with the same speed, memory, and pinout. For new designs, Microchip recommends considering Revision B (EB) parts for prototypes and production, per Microchip's ATSAM4E16E product page, making the EB the preferred ordering choice.
ATSAM4E16EB-AN vs STM32F4 - which is better for industrial Ethernet applications?
Both are viable: the ATSAM4E16EB-AN integrates an Ethernet MAC with dual CAN 2.0B and EBI/EMI on a 120 MHz Cortex-M4 with FPU, which suits industrial gateways natively. STMicroelectronics STM32F4 parts offer comparable Cortex-M4 performance and Ethernet, but pin maps, peripheral register sets, and toolchains differ. Choose the SAM4E when you need the SAM4E ecosystem, existing Atmel/Microchip code base, or EBI memory attachment; choose STM32F4 when ST's HAL, ecosystem, or specific F4 variant features fit better. They are not drop-in interchangeable.
When should I choose the ATSAM4E16EB-AN over smaller SAM4E variants?
Choose ATSAM4E16EB-AN when your design needs maximum memory (1 MB Flash), the full 117 GPIO count, and the 144-pin LQFP footprint - for example, Ethernet gateways, LCD-containing HMI boards using the EBI interface, or multi-bus systems combining CAN, USB, and SPI simultaneously. Smaller SAM4E variants (such as 100-pin C versions) reduce I/O and board cost but sacrifice pins. If your application fits under 100 pins and less Flash, the ATSAM4E16CB is a lower-cost alternative within the same family.
What is the best drop-in replacement for ATSAM4E16EB-AN?
The closest drop-in replacement is the ATSAM4E16EA-AN from Microchip: same SAM4E family, same 1 MB Flash, same 120 MHz Cortex-M4 core, and same 144-pin LQFP package, differing only in die revision. The ATSAM4E16EB-CN is also pin-compatible but carries a commercial temperature grade (0 C to 70 C) instead of extended temperature, so it is a drop-in only for indoor/commercial products. Always verify ordering-code temperature suffixes against your environmental requirements before substituting.
Hey Google, what can replace ATSAM4E16EB-AN?
Pin-compatible replacements for ATSAM4E16EB-AN are limited to Microchip's own SAM4E16E family variants, such as the ATSAM4E16EA-AN (same package and memory, different die revision). Functionally comparable but not pin-compatible alternatives include STMicroelectronics STM32F4 series, NXP LPC408x series, and NXP Kinetis K60 series Cortex-M4 microcontrollers, which offer similar 120 MHz-class performance and Ethernet/CAN connectivity, per distributor equivalent listings - but these require PCB redesign since pinouts differ.
What is the best NXP or ST equivalent for ATSAM4E16EB-AN?
There is no true cross-brand drop-in equivalent: distributor-equivalent listings (e.g., etei.com) name the STMicroelectronics STM32F4 series, NXP LPC408x series, and NXP Kinetis K60 series as Cortex-M4 alternatives with similar processing and peripheral capability to the SAM4E16E. However, none of these share the 144-LQFP pin map of the SAM4E, so adopting them requires a new PCB layout and ported firmware. Treat them as second-source platform choices, not replacements for existing ATSAM4E16EB-AN boards.
What is the pinout and package of ATSAM4E16EB-AN?
The ATSAM4E16EB-AN is housed in a 144-pin LQFP measuring 20 x 20 mm with 0.5 mm lead pitch, offering 117 general-purpose I/O lines. The complete pin assignment - including Ethernet MII/RMII pins, CAN, USB, EBI, and power/ground pins - is defined in the Microchip ATSAM4E series datasheet, section on LQFP144 ordering codes. Because the pinout spans 144 pins with multiplexed functions, consult the official Microchip datasheet pin multiplexing tables rather than third-party summaries when routing critical buses.
Is the ATSAM4E16EB-AN RoHS compliant and lead-free?
Yes. Mouser's listing describes the ATSAM4E16EB-AN as 'LQFP, GREEN, EXT TEMP, MRL B,' where 'GREEN' denotes Microchip's green/RoHS-compliant, halogen-free packaging standard. Microchip's green designation means the package is lead-free and complies with RoHS directives. For formal compliance certificates (REACH, conflict minerals), request Microchip's certificate of conformance or check Microchip's environmental compliance portal for the exact ordering code.
Can ATSAM4E16EB-AN be used for motor control applications?
Yes. The ATSAM4E16EB-AN provides PWM peripheral channels, a 12-bit ADC, DMA, and a 120 MHz Cortex-M4 core with a hardware floating point unit - a combination well suited to field-oriented motor control algorithms, which rely on fast single-precision math. Its CANbus interface integrates with vehicle and industrial motor networks, and the watchdog timer plus brown-out detection add safety layers. Microchip targets the SAM4E family at motor control and solar inverter applications per its product family positioning.

Engineering reference data for ATSAM4E16EB-AN — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4E16EB-AN when you need a 120 MHz Cortex-M4 with Ethernet, dual CAN, USB, EBI external memory, and 117 I/O in a single 144-pin LQFP at extended temperature - the classic profile for industrial gateways, motor drives, and HMI controllers. Choose the ATSAM4E16EB-CN if your product never leaves a climate-controlled environment: identical silicon, typically lower cost, but commercial temperature limits. Choose the ATSAM4E16EA-AN only as a drop-in substitution for existing EA-based designs; for new boards Microchip recommends the EB revision. If your design fits 100 pins and you can live with the smaller pin count, the ATSAM4E16CB family variants reduce cost and board area, but require a new footprint - not a drop-in change. Cross-brand Cortex-M4 alternatives (STM32F4, LPC408x, Kinetis K60) are platform-level options requiring full redesign and firmware porting.

Comparison with Alternatives

Parameter This Product ATSAM4E16EA-AN ATSAM4E16EB-CN
Package 144-LQFP (20x20 mm) 144-LQFP (20x20 mm) - same 144-LQFP (20x20 mm) - same
Brand Microchip Technology Microchip Technology Microchip Technology
Core / Speed ARM Cortex-M4, 120 MHz ARM Cortex-M4, 120 MHz ARM Cortex-M4, 120 MHz
Flash Memory 1 MB 1024 KB 1 MB
Number of I/O 117 117 117
Connectivity CAN, Ethernet, USB, SPI, UART, SD, IrDA, EBI CAN, Ethernet, USB, SPI, UART, SD, IrDA, EBI CAN, Ethernet, USB, SPI, UART, SD, IrDA, EBI

Key Differentiators

  • Extended temperature grade in green packaging (vs ATSAM4E16EB-CN)
  • Revision B die for new designs (vs ATSAM4E16EA-AN)

Design Notes

The 144-LQFP uses a 0.5 mm lead pitch - specify solder mask-defined pads with NSMD copper definition and route escape traces at 4-5 mil width to fan out all 144 pins on two inner layers. A 4-layer stackup (signal / GND / power / signal) is recommended for designs using Ethernet, since the RMII/MII interface needs a clean reference plane under the PHY traces. Keep the Ethernet PHY (e.g., KSZ8081) magnetics within 25 mm of the PHY per the PHY vendor layout guide.

The SAM4E operates from a 3.3 V I/O supply with 1.2 V core regulation. Follow the Microchip datasheet power section for VDDCORE/VDDPLL decoupling: place 100 nF ceramics within 2 mm of each supply pin pair and add bulk 10 uF per supply domain. Ensure brown-out threshold configuration matches your supply ramp - disabling BOD during slow-ramping supplies can leave the core in an undefined state after partial power events.

Pin multiplexing is the most common SAM4E design error: many of the 117 I/O pins serve up to four peripheral functions (A/B/C/D per datasheet multiplexing tables). Lock your pin map in Microchip's ATSAM4E datasheet multiplexing appendix BEFORE PCB routing - discovering late that Ethernet RMII and a desired UART conflict forces a respin. Also verify the die revision in use: Microchip recommends Revision B (EB suffix) parts for new prototypes and production per the ATSAM4E16E product page.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Unknown

Mouser lists the part as 'LQFP,GREEN,EXT TEMP,MRL B' - Microchip's GREEN designation denotes lead-free, halogen-free RoHS-compliant packaging. REACH and conflict minerals status not stated in provided data.

Data verified on: 2026-09-20 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

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