Microchip Technology

ATSAM4LS4AA-MUR - Cortex-M4 48MHz 256KB Flash MCU | Microchip

MPN: ATSAM4LS4AA-MUR ✓ Active
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3.3 V Vdss 90 uA/MHz Id 48-QFN (7x7 mm) with Exposed Pad Package 48 MHz Speed 256 KB (256K x 8) Memory
From $3.55 USD / Unit
MOQ: 1 |
Price updated: 2026-09-19
Volume Pricing
Qty Unit Price Extended
1 $5.42 $5.42
10 $4.88 $48.80
100 $4.35 $435.00
500 $3.92 $1,960.00
1,000 $3.55 $3,550.00
ℹ️ All prices are in USD

ATSAM4LS4AA-MUR Overview

The Microchip Technology ATSAM4LS4AA-MUR is a 32-bit ARM Cortex-M4 flash microcontroller running at 48 MHz with 256 KB of embedded Flash memory, housed in a 48-pin QFN (7x7 mm) package with exposed pad and supplied in tape and reel packaging for industrial temperature ranges.

A microcontroller (MCU) is a single integrated circuit that combines a processor core, memory, and programmable peripherals into one chip, forming the lowest layer of the embedded systems hierarchy: MCU -> embedded processor -> SoC -> computing system. The SAM4L series belongs to Microchip's (formerly Atmel's) ARM-based Flash MCU portfolio, placing a Cortex-M4 core with DSP instructions inside a low-power peripheral set.

Key features include the lowest active-mode power in its class at 90 uA/MHz, sleep mode current down to 1.5 uA, and a wake-up time as short as 1.5 us, the fastest in any Cortex-M4 device according to Microchip. The integrated USB device controller, peripheral event system, and SleepWalking technology allow peripherals to operate and wake the core autonomously, minimizing CPU active time in battery-powered designs.

Architecturally, the SAM4L combines the 32-bit ARM Cortex-M4 RISC processor with a multi-layer bus matrix, flexible event-driven peripherals, and 3.3V operation. The peripheral event system routes signals between peripherals without core intervention, while SleepWalking lets peripherals pre-process data in low-power sleep states, dramatically reducing average system power in duty-cycled applications.

Typical applications include battery-powered sensor nodes, portable medical devices, industrial data loggers, and USB-connected human interface devices, where the combination of 256 KB Flash, USB, and microamp sleep currents fits both connectivity and energy budgets.

Design consideration: budget the Flash wait-state configuration carefully at 48 MHz and use the SleepWalking event system to keep the Cortex-M4 core parked whenever possible.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for ATSAM4LS4AA-MUR — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAM4LS8AA-MUR

✅ Drop-In
📦 48-QFN (7x7 mm)
Flash 512 KB vs 256 KB (+100%), all other specs identical, same pinout

📋 Reference alternative (not in catalog)

ATSAM4LS2AA-MUR

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-Bit · 48 MHz · 128 KB (128K x 8) · 32 KB · 3.3 V · 90 uA/MHz · 1.5 uA

✓ In Stock

$2.98 / Unit

View Datasheet →

ATSAM4LS4AA-MU

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-Bit · 48 MHz · 256 KB (256K x 8) · 90 uA/MHz · 1.5 uA · down to 1.5 us

✓ In Stock

$3.95 / Unit

View Datasheet →

ATSAM4LS4AA-AUR

✅ Drop-In
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-bit · 48 MHz · 256KB (256K x 8) · Flash · 1.8V / 3.3V · 48 · 48-TQFP (7x7 mm)

✓ In Stock

$3.98 / Unit

View Datasheet →

ATSAM4LC4AA-MUR

✅ Drop-In ⚠️ 参数待验证
Microchip Technology
📦 48-QFN (7x7 mm)
ARM Cortex-M4 · 32-Bit · 48 MHz · 256KB (256K x 8) · 32K x 8 · 1.68 V to 3.6 V · 90 uA/MHz · 1.5 uA

✓ In Stock

$3.49 / Unit

View Datasheet →

ATSAM4LS4AA-MUR Maximum Ratings & Electrical Characteristics

Core Processor ARM Cortex-M4
Core Size 32-Bit
Maximum Clock Frequency 48 MHz
Flash Memory 256 KB (256K x 8)
Supply Voltage 3.3 V
Active Mode Current 90 uA/MHz
Sleep Mode Current 1.5 uA
Wake-up Time 1.5 us (minimum)
Connectivity USB Device
Special Features Peripheral Event System, SleepWalking
Package 48-QFN (7x7 mm) with Exposed Pad
Mounting Type Surface Mount
Operating Temperature -40C to +85C (Industrial)
Packaging Tape & Reel (MRL A)
RoHS Status Compliant (Green package)

ATSAM4LS4AA-MUR 48-qfn (7x7 mm) with exposed pad Pin Configuration Guide

Pin configuration for ATSAM4LS4AA-MUR (48-qfn (7x7 mm) with exposed pad package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

48-qfn (7x7 mm) with exposed pad package pinout diagram for ATSAM4LS4AA-MUR

No detailed pinout data available for ATSAM4LS4AA-MUR.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4LS4AA-MUR is suitable for 6 applications: Battery-Powered Sensor Nodes, USB Human Interface Devices, Portable Medical Monitoring, Industrial Data Loggers, Smart Meters and Building Automation, RF-Connected Remote Controls and Beacons.

🧩

Battery-Powered Sensor Nodes

The ATSAM4LS4AA-MUR's 90 uA/MHz active current, 1.5 uA sleep current, and 1.5 us wake-up time make it a leading choice for battery-powered IoT sensor nodes that must run for years on a coin cell or small lithium battery. In a typical wireless sensor node, the Cortex-M4 core wakes, reads an I2C or ADC sensor via the peripheral event system, formats data, and hands it to a radio, spending under a millisecond awake per sample. SleepWalking lets the RTC and peripherals operate while the core stays parked, so average system current can fall to single-digit microamps. The 256 KB Flash accommodates full protocol stacks plus OTA bootloader headroom.

📱

USB Human Interface Devices

The integrated USB device controller of the ATSAM4LS4AA-MUR supports HID class implementations for keyboards, mice, game controllers, and industrial control panels without an external USB interface chip. Running at 48 MHz, the Cortex-M4 core has ample headroom for USB interrupt handling plus HID report processing and even consumer-grade encryption for secure HID tokens. The 1.5 us wake-up time lets the MCU return to deep sleep between USB traffic bursts, meeting aggressive standby power targets in wireless dongles and battery peripherals. The 48-QFN 7x7 mm package fits compact dongle and peripheral PCBs, and Microchip's ASF software framework provides ready-made USB device class drivers to shorten development cycles.

💊

Portable Medical Monitoring

Portable medical devices such as glucose meters, pulse oximeters, and wearable vital-sign monitors benefit directly from the ATSAM4LS4AA-MUR low-power profile. The Cortex-M4 core with DSP instructions accelerates digital filtering of biosignals, while the 256 KB Flash holds signal-processing code, calibration tables, and logging buffers. In a typical wearable monitor, the ADC samples the biosignal front end during short duty-cycled bursts scheduled by the event system, then the MCU computes and displays results, sleeping at 1.5 uA between measurements. The industrial temperature rating of -40C to +85C covers sterilization-adjacent and transport environments, and Microchip's long-lifecycle policy supports medical product roadmaps requiring multi-year sourcing stability.

🏭

Industrial Data Loggers

Industrial data loggers recording temperature, pressure, or energy measurements over months on battery or energy harvesting benefit from the ATSAM4LS4AA-MUR architecture. The 256 KB Flash can buffer substantial logging data or host a local file system, while SleepWalking enables the RTC and ADC to trigger measurement cycles without core involvement. The event system routes comparator or sensor threshold events directly to wake the CPU only on anomalies, extending battery life in hard-to-access installations such as pipeline monitors and cold-chain trackers. The industrial -40C to +85C temperature range and QFN exposed-pad thermal design ensure reliable operation inside sealed enclosures where passive heat dissipation is limited.

Smart Meters and Building Automation

Smart metering and building automation nodes combine periodic measurement, secure communication, and years-long battery or harvested-energy budgets, matching the ATSAM4LS4AA-MUR strengths. The Cortex-M4 core handles metering algorithms and AES-based security at 48 MHz with DSP acceleration, while the 1.5 uA sleep current keeps average draw within energy-harvesting budgets. The peripheral event system timestamps pulses from energy meters without waking the core, and 256 KB Flash retains firmware with dual-image OTA capability for field updates. The exposed-pad QFN provides solid thermal and ground performance for meter PCBs, and the industrial temperature grade supports outdoor cabinet installations across extreme climates.

🌐

RF-Connected Remote Controls and Beacons

Remote controls, key fobs, and Bluetooth beacon tags pair a low-power MCU with an RF transceiver, and the ATSAM4LS4AA-MUR's fast wake-up is decisive here: at 1.5 us, the MCU can wake, configure the radio, and transmit within a millisecond, minimizing airtime and energy per event. The 48 MHz Cortex-M4 processes beacon formatting, encryption, and sensor fusion for smart remotes, while the event system supports capacitive-touch or button wake sources with near-zero latency. With 256 KB Flash, designers can integrate BLE stack variants plus firmware-update capability on the same chip, and the compact 48-QFN 7x7 mm package leaves board area for the antenna and coin cell in slim remote form factors.

What is the ATSAM4LS4AA-MUR microcontroller?
The ATSAM4LS4AA-MUR is a 32-bit ARM Cortex-M4 flash microcontroller from Microchip Technology in the SAM4L series. It runs at up to 48 MHz, integrates 256 KB of Flash memory, operates from a 3.3V supply, and is packaged in a 48-pin QFN (7x7 mm) with exposed pad. According to the Microchip product page, it features a USB device controller, peripheral event system, and SleepWalking low-power technology.
What are the key specifications of ATSAM4LS4AA-MUR that engineers should know?
The ATSAM4LS4AA-MUR is an ARM Cortex-M4 MCU with 48 MHz maximum clock, 256 KB Flash, 3.3V operation, and a 48-QFN 7x7 mm package. Its headline low-power figures are 90 uA/MHz active current, 1.5 uA sleep current, and 1.5 us wake-up time, which Microchip states is the shortest wake-up among Cortex-M4 devices. Industrial temperature range is -40C to +85C, and the part ships in tape and reel.
What is the price of ATSAM4LS4AA-MUR?
As of 2026-09-20, ATSAM4LS4AA-MUR pricing at XAIPART starts at approximately 5.42 USD for single-unit quantities, dropping to about 3.55 USD at 1000-unit volume. Distributors including DigiKey, Mouser, and Octopart list the part with pricing from 9 distributors; exact unit prices vary by distributor stock position and order quantity, so request a quote for volume commitments.
Where to buy ATSAM4LS4AA-MUR online?
The ATSAM4LS4AA-MUR can be purchased online from XAIPART as well as authorized distributors DigiKey (part page 3900014), Mouser, Hotenda, Ampheo, and spot-market suppliers like Ichome and Avaq. DigiKey and Mouser typically show in-stock inventory that ships same day. For production volumes, compare bulk price breaks across distributors via Octopart, which aggregates 9 distributors for this Microchip part.
What is the difference between ATSAM4LS4AA-MUR and ATSAM4LS8AA-MUR?
The only significant difference is Flash memory: the ATSAM4LS4AA-MUR contains 256 KB while the ATSAM4LS8AA-MUR contains 512 KB of Flash. Both are SAM4L series Cortex-M4 parts in the same 48-QFN (7x7 mm) package with the same 48 MHz core, USB device, and low-power features. If code size approaches the 256 KB limit, the LS8 variant provides headroom on the same footprint.
What is the difference between ATSAM4LS4AA-MUR and ATSAM4LS2AA-MUR?
The ATSAM4LS2AA-MUR has half the Flash of the ATSAM4LS4AA-MUR (128 KB versus 256 KB) but shares the same 48 MHz Cortex-M4 core, package, USB device controller, and SleepWalking feature set. Choose the LS2 variant to save cost when firmware fits in 128 KB; choose the LS4 for larger stacks, OTA-capable bootloaders, or data logging buffers.
When should I choose ATSAM4LS4AA-MUR over a PIC16F or STM32 alternative?
Choose the ATSAM4LS4AA-MUR when battery life dominates the design: its 90 uA/MHz active mode, 1.5 uA sleep, and 1.5 us wake-up outperform typical Cortex-M0+ and general-purpose M4 competitors in duty-cycled sensor applications. The integrated peripheral event system and SleepWalking further reduce CPU wake-ups. If cost is the primary driver and power is secondary, lower-cost MCUs may suffice; if extreme performance above 48 MHz is needed, larger SAM4E or STM32F4 parts are better fits.
Is ATSAM4LS4AA-MUR suitable for battery-powered wearable applications?
Yes, the ATSAM4LS4AA-MUR is well suited for wearables and battery-powered devices. Its 1.5 uA sleep current and 90 uA/MHz active efficiency extend battery life, and the 1.5 us wake-up time enables fast, responsive sensing bursts that spend minimal time awake. The 48-QFN 7x7 mm package with exposed pad fits compact PCBs, and the USB device port supports charging-and-communications cradles without a separate USB chip.
What is the best drop-in replacement for ATSAM4LS4AA-MUR?
The closest drop-in replacements are same-family Microchip SAM4L variants: ATSAM4LS8AA-MUR (512 KB Flash, same package and pinout) and ATSAM4LS2AA-MUR (128 KB Flash, same package). Because they share the 48-QFN (7x7 mm) footprint and pin assignment, firmware changes are limited to linker settings. Verify Flash density requirements before swapping downward, since 256 KB firmware will not fit in the LS2 variant.
Can ATSAM4LS8AA-MUR replace ATSAM4LS4AA-MUR?
Yes. The ATSAM4LS8AA-MUR is pin-to-pin compatible with the ATSAM4LS4AA-MUR in the same 48-QFN (7x7 mm) package and doubles Flash to 512 KB. All core, peripheral, and low-power specifications are identical, so it is a safe upward drop-in for shortage situations. No PCB or schematic changes are required; only confirm the linker script reflects 512 KB Flash and recompile firmware.
Is there an STMicroelectronics or NXP equivalent for ATSAM4LS4AA-MUR?
The verified cross-reference data did not surface a confirmed pin-to-pin cross-brand equivalent for the 48-QFN ATSAM4LS4AA-MUR. STMicroelectronics STM32L4 and NXP LPC54 parts offer similar Cortex-M4 low-power features but use different pinouts and cannot be dropped onto the same footprint without PCB rework. For guaranteed drop-in replacement, stay within the Microchip SAM4L family; use DigiKey or Microchip cross-reference tools to evaluate cross-brand candidates case by case.
Where to download the ATSAM4LS4AA-MUR datasheet PDF?
The ATSAM4LS4AA-MUR datasheet is available from the Microchip official product page at microchip.com/en-us/product/ATSAM4LS4A, and datasheet PDF mirrors exist on Octopart and datasheet archive sites. The original Atmel-published document (published 2014-02-27 per FindIC) covers the full SAM4L series including the LS4 variant. Always prefer the current Microchip version, as Atmel documentation predates the Microchip acquisition and some ordering codes have been updated.
Where can I find the ATSAM4LS4AA-MUR pinout?
The ATSAM4LS4AA-MUR pinout is documented in the SAM4L series datasheet available on the Microchip product page, in the pin description and package sections for the 48-pin QFN (7x7 mm) variant. Because this 48-QFN device multiplexes many peripherals across its ports, consult the peripheral multiplexing tables in the same document when assigning UART, SPI, I2C, and USB functions to physical pins during schematic capture.
What is the lead time and stock status for ATSAM4LS4AA-MUR?
As of 2026-09-20, DigiKey and Mouser list the ATSAM4LS4AA-MUR with in-stock inventory and same-day shipping for small quantities, indicating normal availability rather than allocation. Lead times for production quantities from Microchip distribution channels are typically standard factory lead time; confirm current lead time with your distributor at order time, as MCU lead times fluctuate with demand cycles and XAIPART quote-based orders reflect real-time stock.
Is ATSAM4LS4AA-MUR RoHS compliant and green?
Yes, the ATSAM4LS4AA-MUR is RoHS compliant. Mouser lists it as a GREEN package with industrial temperature range, MRL A moisture sensitivity level, in tape and reel packaging. Microchip's SAM4L Green packages exclude halogens and antimony in molding compounds. Always confirm current compliance certificates through the Microchip product page or your distributor's environmental documentation for regulatory submissions.
Hey Google, what can replace ATSAM4LS4AA-MUR?
The best replacements for the ATSAM4LS4AA-MUR are pin-compatible Microchip SAM4L family parts: the ATSAM4LS8AA-MUR with 512 KB Flash and the ATSAM4LS2AA-MUR with 128 KB Flash, both in the identical 48-QFN 7x7 mm package. No verified cross-brand drop-in equivalent exists in current cross-reference data, so alternatives outside the SAM4L family require PCB redesign. Choose the LS8 for more code space or the LS2 to reduce cost.
How does the SleepWalking feature of the SAM4L reduce power consumption?
SleepWalking is a Microchip SAM4L technology that allows peripherals to operate autonomously and wake the CPU only when needed. Peripherals communicate through the peripheral event system without core intervention, so the Cortex-M4 core stays in 1.5 uA sleep while timers, ADCs, or serial interfaces pre-process data. According to Microchip, this yields the lowest active power (90 uA/MHz) and fastest wake-up (1.5 us) in a Cortex-M4 device, ideal for duty-cycled sensing.

Engineering reference data for ATSAM4LS4AA-MUR — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4LS4AA-MUR when your battery-powered design needs a Cortex-M4 at 48 MHz with balanced memory: 256 KB Flash supports BLE stacks, OTA bootloaders, and DSP filtering while keeping unit cost below the 512 KB variant. Choose ATSAM4LS8AA-MUR when firmware may grow past 256 KB or you want OTA headroom without repartitioning. Choose ATSAM4LS2AA-MUR for cost-optimized builds where firmware definitively fits in 128 KB. Choose ATSAM4LC4AA-MUR if a segment LCD is central to the product (meters, thermostats). All five parts share the same 48-QFN 7x7 mm footprint, so selection can be deferred late in the project or swapped during shortages without PCB changes. No verified cross-brand pin-compatible equivalent exists; staying within SAM4L guarantees drop-in replacement.

Comparison with Alternatives

Parameter This Product ATSAM4LS8AA-MUR ATSAM4LS2AA-MUR ATSAM4LS4AA-MU ATSAM4LC4AA-MUR
Package 48-QFN (7x7 mm) EP 48-QFN (7x7 mm) EP - same 48-QFN (7x7 mm) EP - same 48-QFN (7x7 mm) EP - same 48-QFN (7x7 mm) EP - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Flash Memory 256 KB 512 KB 128 KB 256 KB 256 KB
Core / Clock ARM Cortex-M4, 48 MHz ARM Cortex-M4, 48 MHz ARM Cortex-M4, 48 MHz ARM Cortex-M4, 48 MHz ARM Cortex-M4, 48 MHz
Active Mode Current 90 uA/MHz 90 uA/MHz 90 uA/MHz 90 uA/MHz 90 uA/MHz
Sleep Current / Wake-up 1.5 uA / 1.5 us 1.5 uA / 1.5 us 1.5 uA / 1.5 us 1.5 uA / 1.5 us 1.5 uA / 1.5 us
USB Device Yes Yes Yes Yes Yes

Key Differentiators

  • Fastest wake-up in any Cortex-M4 MCU (vs ATSAM4LS8AA-MUR)
  • Balanced 256 KB Flash for OTA-capable designs (vs ATSAM4LS2AA-MUR)
  • Class-leading low power per MHz (vs ATSAM4LC4AA-MUR)

Design Notes

Exploit SleepWalking and the peripheral event system to minimize core active time. Schedule ADC sampling and communication DMA transfers from the RTC or peripherals so the Cortex-M4 core wakes only to process results; with 90 uA/MHz active current versus 1.5 uA sleep, every millisecond shaved off duty-cycled wake periods directly extends battery life. Estimated: at 10 wake-ups/second of 1 ms each at 48 MHz, average current is roughly 90 uA x duty cycle (1%) plus 1.5 uA sleep, about 2.4 uA plus overhead, enabling multi-year coin-cell operation.

The 48-QFN (7x7 mm) exposed pad serves as the primary ground and thermal path. Connect the exposed pad to a solid ground plane with an array of at least 4x4 vias under the pad; this reduces ground bounce for the 48 MHz core and improves thermal relief. Place 100 nF decoupling capacitors within 2 mm of each VDDIO/VDDCORE pin pair, plus a bulk 4.7-10 uF capacitor near the supply entry. Follow Microchip's SAM4L evaluation-kit layout as a reference for crystal and USB routing.

Confirm Flash density and ordering-code fit before substituting within the SAM4L family: ATSAM4LS2AA (128 KB) will not hold 256 KB firmware, and LC-series variants differ in peripheral multiplexing despite sharing the package. Also verify the Flash wait-state configuration after any clock change to 48 MHz, and re-check the exact moisture sensitivity level (MRL A per Mouser) and reel quantity when planning reflow schedules. Industrial temperature is -40C to +85C; do not use this industrial-grade part in automotive-underhood applications without additional qualification.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Unknown

Mouser lists the part as GREEN with industrial temperature and MRL A moisture sensitivity level. RoHS and green (halogen-free) status per Microchip/Mouser listings; REACH and conflict-minerals declarations not stated in provided data.

Data verified on: 2026-09-20 — data verified and curated by XAIPART's component engineering team

Related Searches

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Related Components & Terms

Microchip Technology Atmel Corporation ATSAM4LS4AA-MUR ATSAM4LS8AA-MUR ATSAM4LS2AA-MUR ATSAM4LC4AA-MUR SAM4L series ARM Cortex-M4 32-bit microcontroller Flash MCU embedded processor QFN-48 surface mount SleepWalking peripheral event system USB device RoHS industrial temperature range tape and reel low-power embedded design battery-powered sensor node wake-up time quiescent sleep current
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