Microchip Technology

ATSAM4LS4AA-AUR - 48MHz Cortex-M4 MCU, 256KB Flash | Microchip

MPN: ATSAM4LS4AA-AUR βœ“ Active
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1.8V / 3.3V Vdss 90 uA/MHz Id 48-TQFP (7x7 mm) Package 48 MHz Speed 256KB (256K x 8) Memory
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Price updated: 2026-09-19
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100 $4.79 $479.00
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ℹ️ All prices are in USD

ATSAM4LS4AA-AUR Overview

The Microchip Technology ATSAM4LS4AA-AUR is a 32-bit ARM Cortex-M4 Flash microcontroller running at up to 48 MHz with 256KB of embedded Flash memory, integrated crypto acceleration, and a 48-pin TQFP (7x7 mm) package for industrial-temperature applications.

A microcontroller (MCU) is a single-chip computer that integrates a processor core, non-volatile Flash program memory, SRAM data memory, and a rich set of peripherals such as timers, serial interfaces, and analog converters. Within the power-management hierarchy of embedded systems, an MCU is the central control element that orchestrates sensors, communication, and user interfaces. The ATSAM4LS4AA-AUR belongs to Microchip's (formerly Atmel) SAM4L family, a line of ultra-low-power ARM Cortex-M4 Flash microcontrollers positioned above the SAM D20 Cortex-M0+ series and alongside Cortex-M4 competitors from other vendors.

The defining feature of the ATSAM4LS4AA-AUR is class-leading power efficiency: 90 uA/MHz in active mode, 1.5 uA in sleep mode, and wake-up times down to 1.5 us - the shortest in a Cortex-M4 device according to the manufacturer. This combination of low active power and instant wake-up makes it possible to duty-cycle demanding DSP workloads from coin cells or energy-harvesting supplies. The device also integrates a USB device controller, a peripheral event system that routes signals between peripherals without CPU intervention, and the innovative SleepWalking feature, which lets peripherals wake the core only when preprogrammed conditions are met.

The crypto-capable variant designated by the MRL/CRYPTO suffix adds hardware security acceleration, offloading symmetric and hash operations from software. Operating from a 1.8V to 3.3V supply (per FindIC specification data), the industrial-temperature-grade part suits -40C to +85C environments.

Typical applications include battery-powered sensor nodes, portable medical devices, industrial control panels, and USB-connected data loggers - all scenarios where both 32-bit compute (single-cycle MAC, hardware divide for Cortex-M4 DSP instructions) and microamp sleep currents are mandatory.

For design, exploit the SleepWalking and peripheral event system to keep the CPU asleep; the wake-up penalty of only 1.5 us means aggressive power gating rarely impacts responsiveness. Size the decoupling network per the SAM4L datasheet recommendations for the 48-TQFP power pins.

This page synthesizes distributor pricing, drop-in family alternatives, and practical low-power design guidance not consolidated in the manufacturer datasheet, giving engineers a single citable reference for the ATSAM4LS4AA-AUR.

Drop-in alternatives for ATSAM4LS4AA-AUR β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAM4LS4AA-AUR (same form factor and footprint) β€” differing in Package, RoHS Status, Operating Temperature, Packaging, Series.

Microchip Technology
Package: 64-QFN (9x9 mm), exposed pad
RoHS Status: RoHS compliant (Green package per Utmel listing)
Operating Temperature: -40C to +85C (Industrial)
Compare with ATSAM4LS4AA-AUR β†’
Microchip Technology
RoHS Status: Compliant (GREEN, MRL A)
Operating Temperature: -40C to +85C (industrial)
Compare with ATSAM4LS4AA-AUR β†’
Microchip Technology
Package: 64-TQFP (10x10 mm), Exposed Pad
RoHS Status: Compliant (Green per Mouser listing)
Operating Temperature: -40C to +85C (Industrial)
Compare with ATSAM4LS4AA-AUR β†’
Microchip Technology
Operating Temperature: Industrial temperature range (-40C to +85C)
Compare with ATSAM4LS4AA-AUR β†’
Microchip Technology
Package: 64-TQFP (10x10 mm)
Operating Temperature: -40C to +85C (Industrial)
Packaging: Tape & Reel (T/R)
Compare with ATSAM4LS4AA-AUR β†’
Microchip Technology
Package: 100-TQFP (14x14 mm)
RoHS Status: Compliant (Green package per Mouser)
Operating Temperature: -40C to +85C (Industrial)
Compare with ATSAM4LS4AA-AUR β†’

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ATSAM4LS4AA-AUR Maximum Ratings & Electrical Characteristics

Core Processor ARM Cortex-M4
Core Size 32-bit
Maximum Clock Frequency 48 MHz
Flash Memory 256KB (256K x 8)
Program Memory Type Flash
Supply Voltage 1.8V / 3.3V
Number of Pins 48
Package 48-TQFP (7x7 mm)
Mounting Type Surface Mount
Operating Temperature Industrial (-40C to +85C)
Active Mode Current 90 uA/MHz
Sleep Mode Current 1.5 uA
Wake-up Time Down to 1.5 us
USB USB device controller
Special Features Crypto acceleration, Peripheral Event System, SleepWalking
Packaging Tape & Reel (R suffix)

ATSAM4LS4AA-AUR 48-tqfp (7x7 mm) Pin Configuration Guide

Pin configuration for ATSAM4LS4AA-AUR (48-tqfp (7x7 mm) package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

48-tqfp (7x7 mm) package pinout diagram for ATSAM4LS4AA-AUR

No detailed pinout data available for ATSAM4LS4AA-AUR.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4LS4AA-AUR is suitable for 6 applications: Battery-Powered IoT Sensor Nodes, Portable Medical Monitoring Devices, USB Data Loggers and Field Instruments, Industrial Control and HMI Panels, Secure Embedded Systems and Firmware Protection, Energy Harvesting and Coin-Cell Systems.

🧩

Battery-Powered IoT Sensor Nodes

The ATSAM4LS4AA-AUR fits battery-powered sensor nodes because its 90 uA/MHz active current, 1.5 uA sleep current, and 1.5 us wake-up minimize the dominant energy cost of duty-cycled sensing: repeated sleep-wake transitions. A node that samples every few seconds can remain asleep more than 99% of the time, while the Cortex-M4's DSP instructions process filter or FFT workloads quickly enough to return to sleep almost immediately. The SleepWalking feature lets a timer or analog comparator wake the core only when a threshold is crossed, and the peripheral event system chains ADC-to-DMA transfers without CPU involvement. At 1.8V operation the MCU can run directly from a discharged lithium coin cell rail with proper supervision.

πŸ’Š

Portable Medical Monitoring Devices

Wearable and portable medical instruments such as pulse oximeters, ECG patches, and glucose monitors benefit from the ATSAM4LS4AA-AUR's combination of 32-bit compute and microamp standby. The Cortex-M4 single-cycle MAC accelerates digital filtering of physiological signals without an external DSP, while 256KB Flash holds protocol stacks and calibration tables on one chip. The industrial temperature grade (-40C to +85C) covers autoclave-adjacent storage and transport conditions, and the crypto hardware supports patient-data protection at the device level. With 1.5 us wake-up, an interrupt from a vital-sign front end is serviced with negligible latency, and the USB device port enables direct data offload to clinical hardware without a separate USB bridge IC.

πŸ–₯️

USB Data Loggers and Field Instruments

The integrated USB device controller of the ATSAM4LS4AA-AUR removes the need for an external USB interface chip in data loggers, handheld meters, and field instruments. Firmware can implement USB CDC/MSD classes while the Cortex-M4 core concurrently processes sensor data; 256KB Flash accommodates both the USB stack and the application. SleepWalking permits logging tasks to continue at low power while USB remains available only when a host connects. The 1.8V/3.3V supply range allows operation from a single Li-ion cell through a small LDO. Designers should budget USB VBUS detection per the SAM4L datasheet and place the 48-TQFP decoupling capacitors close to the supply pins for signal integrity on the 48 MHz domain.

🏭

Industrial Control and HMI Panels

Factory panels, motor-control supervisory nodes, and human-machine interfaces operate for years in -40C to +85C environments, which the industrial-grade ATSAM4LS4AA-AUR addresses directly. The 48 MHz Cortex-M4 with hardware divide executes PID loops and Modbus/CAN gateway code comfortably, and hardware crypto supports secure firmware updates in the field - increasingly mandatory in industrial networks. The peripheral event system reduces interrupt latency and jitter by routing timer and ADC events without the CPU. At 3.3V, GPIOs drive optocouplers and level shifters for 24V industrial signaling. Tape-and-reel packaging (R suffix) supports automated pick-and-place for panel volume production.

πŸŽ₯

Secure Embedded Systems and Firmware Protection

Products that must authenticate accessories, encrypt stored data, or protect firmware IP can use the ATSAM4LS4AA-AUR's integrated crypto acceleration rather than adding a separate secure element for symmetric operations. The Cortex-M4 core offloads hash and cipher workloads to hardware, reducing both execution time and side-channel exposure compared with pure software implementations. In connected devices, the same crypto block supports signed-boot verification at power-up, with the 1.5 us wake-up ensuring verification adds no perceptible start-up delay. Combined with 256KB Flash for application plus key-handling code, this makes the part a compact choice for secure sensors, licensed peripherals, and anti-counterfeiting nodes in consumer and industrial ecosystems.

⚑

Energy Harvesting and Coin-Cell Systems

Systems powered by photovoltaic, thermoelectric, or RF energy harvesting demand ultra-low average current, and the ATSAM4LS4AA-AUR's 1.5 uA sleep current fits within typical harvester budgets. Because wake-up takes only 1.5 us, the MCU can execute burst computations and return to sleep so quickly that transient load events stay short enough for small storage capacitors. The peripheral event system and SleepWalking allow sensor front ends to pre-process data autonomously, waking the core only for decisions. Running at 1.8V matches the output range of many boost converters used with harvesters. Engineers should verify BOD thresholds against the harvester's cold-start voltage per the SAM4L family datasheet to guarantee reliable brown-out behavior.

What is the ATSAM4LS4AA-AUR microcontroller?
The ATSAM4LS4AA-AUR is a 32-bit ARM Cortex-M4 Flash microcontroller from Microchip Technology (originally Atmel), part of the SAM4L family. It runs at up to 48 MHz with 256KB of Flash memory in a 48-pin TQFP (7x7 mm) package. According to Microchip's product page, it delivers 90 uA/MHz active current, 1.5 uA sleep current, and 1.5 us wake-up time - the shortest wake-up of any Cortex-M4 device.
How much Flash memory does the ATSAM4LS4AA-AUR have?
The ATSAM4LS4AA-AUR contains 256KB (256K x 8) of embedded Flash program memory, as confirmed by DigiKey's product listing. The '4' in the SAM4LS4 naming denotes the 256KB Flash density tier. Flash is programmed in-system via SWD or UART, and the device also provides the crypto hardware peripheral found in the SAM4L family for secure firmware applications.
What is the operating voltage of the ATSAM4LS4AA-AUR?
The ATSAM4LS4AA-AUR operates from a 1.8V to 3.3V supply, with FindIC specification data listing 1.8V/3.3V operating points. This wide range lets the MCU run directly from a single LiSOCl2 cell (3.6V peak must be checked against the datasheet absolute maximum) or from a 3.3V rail, while brown-out and BOD circuits supervise the supply during battery discharge.
What is the price of ATSAM4LS4AA-AUR?
The ATSAM4LS4AA-AUR is listed at approximately $5.80 USD at single-unit quantity as of 2026-09-20, based on the icDirectory reference price of $5.79701. Distributor pricing typically steps down to the $4 to $5 range at 100-piece volumes. For current exact pricing across DigiKey, Mouser, and Octopart-listed distributors, check the live price table on this page, which is refreshed from distributor feeds.
Where can I buy ATSAM4LS4AA-AUR online?
You can buy the ATSAM4LS4AA-AUR from XAIPART on this page, as well as from major distributors including DigiKey (part 3995718), Mouser, and six distributors tracked by Octopart. Stock levels reported recently include roughly 23,700 units (icDirectory) and 13,250 units (Octopart, updated Aug 2025). XAIPART offers quote-based ordering with direct access to tape-and-reel quantities for production builds.
Is ATSAM4LS4AA-AUR in stock and what is the lead time?
Yes, the ATSAM4LS4AA-AUR is widely stocked: DigiKey states 'Order today, ships today,' and aggregate stock reports show 23,700 units at icDirectory and 22,530 to 23,340 units tracked on Octopart regional sites. Lead time from in-stock distributors is typically same-day to a few days. For high-volume tape-and-reel orders beyond distributor stock, factory lead times of 12-26 weeks can apply, so plan production purchases accordingly.
What is the difference between ATSAM4LS4AA-AUR and ATSAM4LC4AA-AUR?
The core difference is the peripheral set: the SAM4L 'S' (standard) series in the ATSAM4LS4AA-AUR vs. the SAM4L 'C' (picoPower/low-power optimized) series in the ATSAM4LC4AA-AUR, which trades some peripherals for even lower power modes. Both are Cortex-M4, 48 MHz, 256KB Flash, and share the same 48-pin TQFP package, making them largely drop-in interchangeable. Verify the specific peripheral list (e.g., USB, crypto, TC counts) in the SAM4L datasheet before swapping.
What is the best drop-in replacement for ATSAM4LS4AA-AUR?
The best drop-in replacements are same-family SAM4L parts in the same 48-pin TQFP package: ATSAM4LC4AA-AUR (lower-power C-series variant), ATSAM4LC4BA-AUR (flagged by DigiKey's cross-reference tool), ATSAM4LS4BA-AUR, ATSAM4LS4CA-AUR (different peripheral mixes), and ATSAM4LS8AA-AUR (same package, 512KB Flash). All are pin-compatible Cortex-M4 devices; only firmware-level peripheral differences need revalidation.
Can ATSAM4LS4AA-AUR replace ATSAM3S4AA-AU?
Not as a strict drop-in. Octopart lists ATSAM4LS4AA-AUR vs ATSAM3S4AA-AU comparisons, but the SAM3S is a Cortex-M3 with a different peripheral register map, so while pinout overlap is high in 48-pin TQFP, the flash programming and peripheral drivers differ. Migration is a firmware rework, not a socket swap. If you need Cortex-M4 performance with SAM3S-like simplicity, the SAM4L is the designated successor family; budget a software migration cycle and re-run hardware validation.
Is there a cross-brand equivalent for ATSAM4LS4AA-AUR?
No verified cross-brand pin-to-pin equivalent exists in our cross-reference data. Parts such as the ATSAMD21G18A-AU (Cortex-M0+, same package) or STMicro/STM32L4 devices are parametrically similar Cortex-M MCUs but are not pin-compatible with the SAM4L 48-TQFP pinout. Cross-brand MCU swaps always require PCB redesign because pin multiplexing differs. For a same-footprint path, stay within the Microchip SAM4L family; consult the SAM4L datasheet pin-multiplexing tables to confirm function-for-function matches.
When should I choose ATSAM4LS4AA-AUR over ATSAMD21G18A-AU?
Choose the ATSAM4LS4AA-AUR when you need Cortex-M4 DSP capability (single-cycle MAC, hardware divide) plus the SAM4L's ultra-low-power profile (1.5 uA sleep, 1.5 us wake-up) and crypto acceleration. Choose the ATSAMD21G18A-AU when a simpler Cortex-M0+ suffices and cost is the priority. Both come in 48-pin TQFP packages, but their pinouts differ, so the choice must be made before layout. The SAM4L wins for battery-powered signal-processing nodes; the SAM D21 wins for cost-sensitive basic control.
Is ATSAM4LS4AA-AUR suitable for battery-powered IoT sensor nodes?
Yes - it is one of the most suitable Cortex-M4 MCUs for this use. With 90 uA/MHz active current, 1.5 uA sleep current, and 1.5 us wake-up, a node sampling every few seconds spends nearly all its life in sleep. The SleepWalking feature lets peripherals (e.g., a threshold comparator or timer) wake the CPU only on events, and the peripheral event system chains peripherals without core involvement. USB device connectivity further enables direct configuration links during commissioning without additional interface ICs.
Where can I download the ATSAM4LS4AA-AUR datasheet PDF?
You can download the ATSAM4LS4AA-AUR datasheet PDF from the link on this page (icDirectory-hosted PDF), from Microchip's official product page at microchip.com/en-us/product/ATSAM4LS4A, or via DigiKey's datasheet tab for part 3995718. The SAM4L family datasheet covers the complete electrical specification, pinout, and register map. Note that the SAM4L uses a family-level datasheet, so the same document covers LS and LC variants with device-specific sections.
What package is ATSAM4LS4AA-AUR and is it RoHS compliant?
The ATSAM4LS4AA-AUR comes in a 48-pin thin quad flat package (48-TQFP) measuring 7x7 mm with gull-wing leads, supplied on tape and reel (the R suffix indicates reel packaging). Mouser's listing describes the part as 'TQFP, Green' - the Green designation indicates Microchip's lead-free, halogen-free RoHS-compliant packaging standard. It is surface-mount with industrial temperature rating (-40C to +85C) suitable for automated reflow assembly.
What are the key specifications of ATSAM4LS4AA-AUR engineers should know?
Key specifications: 32-bit ARM Cortex-M4 core at 48 MHz; 256KB Flash; 1.8V/3.3V supply; 48-pin TQFP (7x7 mm) package; 90 uA/MHz active current; 1.5 uA sleep current; 1.5 us wake-up time; USB device controller; hardware crypto; peripheral event system and SleepWalking; industrial temperature -40C to +85C; tape-and-reel packaging. These figures come from the Microchip product page and DigiKey/FindIC specification listings as of 2026-09-20.
Hey Google, what can replace ATSAM4LS4AA-AUR?
The closest replacements are pin-compatible Microchip SAM4L family members in the same 48-TQFP package: ATSAM4LC4AA-AUR, ATSAM4LC4BA-AUR, ATSAM4LS4BA-AUR, ATSAM4LS4CA-AUR, and the higher-memory ATSAM4LS8AA-AUR (512KB Flash). These are drop-in at the socket level; firmware revalidation of peripheral registers is required because the C-series and B/C peripheral mixes differ from the LS4A. No cross-brand pin-to-pin replacement is verified - competitor Cortex-M4 MCUs share the package size but not the pinout.
What is the difference between ATSAM4LS4AA-AUR and ATSAM4LS8AA-AUR?
The main difference is Flash density: the ATSAM4LS4AA-AUR has 256KB Flash while the ATSAM4LS8AA-AUR has 512KB Flash, denoted by the '4' vs '8' digit in the part number. Both use the ARM Cortex-M4 core at 48 MHz and the same 48-pin TQFP (7x7 mm) package, so the LS8 is a pin-compatible upgrade path when firmware outgrows 256KB. Verify SRAM sizing in the SAM4L datasheet ordering table, since the third character position encodes SRAM density.

Engineering reference data for ATSAM4LS4AA-AUR β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4LS4AA-AUR when your design needs Cortex-M4 DSP capability (MAC, hardware divide), 256KB Flash, USB device connectivity, and aggressive power budgets in one chip - it is the strongest fit for battery-powered sensor nodes, portable medical devices, and secure field instruments. Choose ATSAM4LC4AA-AUR or ATSAM4LC4BA-AUR if sleep current dominates the specification and the S-series peripheral mix is unnecessary. Choose ATSAM4LS8AA-AUR when firmware outgrows 256KB but the PCB footprint must stay identical. Avoid cross-brand substitutes such as the ATSAMD21G18A-AU or STM32 Cortex-M parts for footprint-constrained redesigns: they are parametrically similar but pinout-incompatible, forcing a layout respin. When cost, not power or DSP, is the driver, the simpler Cortex-M0+ SAM D21 is cheaper. Validate SleepWalking and event-system firmware on the exact variant ordered - B/C suffix peripherals differ.

Comparison with Alternatives

Parameter This Product ATSAM4LC4AA-AUR ATSAM4LC4BA-AUR ATSAM4LS4BA-AUR ATSAM4LS4CA-AUR ATSAM4LS8AA-AUR
Package 48-TQFP (7x7 mm) 48-TQFP (7x7 mm) - same 48-TQFP (7x7 mm) - same 48-TQFP (7x7 mm) - same 48-TQFP (7x7 mm) - same 48-TQFP (7x7 mm) - same
Brand Microchip Technology (Atmel) Microchip Technology (Atmel) Microchip Technology (Atmel) Microchip Technology (Atmel) Microchip Technology (Atmel) Microchip Technology (Atmel)
Core ARM Cortex-M4, 32-bit ARM Cortex-M4, 32-bit ARM Cortex-M4, 32-bit ARM Cortex-M4, 32-bit ARM Cortex-M4, 32-bit ARM Cortex-M4, 32-bit
Max Clock Frequency 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
Flash Memory 256KB 256KB 256KB 256KB 256KB 512KB
Temperature Grade Industrial (-40C to +85C) Industrial Industrial Industrial Industrial Industrial

Key Differentiators

  • Shortest wake-up time in a Cortex-M4 device (vs ATSAMD21G18A-AU)
  • Integrated hardware crypto in the MCU (vs ATSAMD21G18A-AU)
  • Memory upgrade without PCB change (vs ATSAM4LS8AA-AUR)

Design Notes

To achieve the advertised 1.5 uA sleep current, all unused GPIOs must be configured as inputs with pull-downs disabled or grounded outputs per the SAM4L datasheet low-power checklist; a single floating input can dominate the entire sleep budget. Clock the device from the internal RC oscillator during sleep-critical phases and shut down the PLL and external crystal. Use the BOD in monitoring (not reset-generating) mode in battery products if the brown-out threshold current would exceed the sleep budget. Estimated: at 1.5 uA sleep, a 220 mAh CR2032 supports roughly 16 years of standby before self-discharge limits dominate.

For the 48-TQFP (7x7 mm) package, place one 100 nF ceramic capacitor within 2 mm of each VDD/VDDCORE pair and one bulk 4.7-10 uF capacitor per power domain, per the SAM4L datasheet layout guidance. Use a solid ground plane and keep the VDDCORE decoupling loop minimal - the core supply has the highest transient di/dt at 48 MHz. NC pins must be left unconnected exactly as the pin-multiplexing table specifies; tying them can enable internal test modes.

SAM4L variants (LS vs LC, A/B/C suffixes) differ in peripheral sets and register maps despite identical pinouts, so firmware written for one variant can silently mis-configure another. Confirm the exact device ID register at startup and gate peripheral drivers accordingly. The 'R' suffix means tape-and-reel: if hand assembly or small reflow runs are planned, order the tray (-AU) suffix instead, since reel moisture-bake and MSL handling apply. Verify USB VBUS presence detection wiring before first board bring-up - it is a common first-boot failure.

Route the 48 MHz system clock domain traces short and keep switching GPIOs away from the crystal and SWD debug lines. For USB D+/D- traces, maintain 90-ohm differential impedance and length-match within 1 mm when the connector is more than 30 mm from the MCU. The peripheral event system routes internal signals, but external interrupt lines should still avoid crossing power-domain boundaries on two-layer boards, which typically lack the ground stitching needed for clean edge rates at Cortex-M4 GPIO speeds.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Unknown

Mouser lists the part as 'TQFP, Green' - Microchip's Green designation denotes lead-free, halogen-free RoHS-compliant packaging. REACH and conflict-minerals declarations not stated in the provided data.

Data verified on: 2026-09-20 β€” data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology Atmel ATSAM4LS4AA-AUR SAM4L family ARM Cortex-M4 microcontroller Flash microcontroller TQFP-48 QFP package family surface mount USB device controller SleepWalking Peripheral Event System hardware crypto 1.5 uA sleep current 90 uA/MHz RoHS Industrial temperature grade battery-powered sensor node portable medical device energy harvesting ATSAMD21G18A-AU ATSAM4LC4AA-AUR ATSAM4LS8AA-AUR tape and reel
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