Microchip Technology

ATSAMD51N19A-AF - 120MHz Cortex-M4F MCU, 512KB Flash | Microchip

MPN: ATSAMD51N19A-AF βœ“ Active
In Stock Ships in 1-3 business days
1.62 V to 3.6 V Vdss 100-pin TQFP (14x14 mm) Package 120 MHz Speed 512 KB (dual-panel, with ECC) Memory
From $5.41 USD / Unit
MOQ: 1 |
Price updated: 2026-09-21
Volume Pricing
Qty Unit Price Extended
1 $8.42 $8.42
10 $7.58 $75.80
100 $6.74 $674.00
500 $6.05 $3,025.00
1,000 $5.41 $5,410.00
ℹ️ All prices are in USD

ATSAMD51N19A-AF Overview

The Microchip ATSAMD51N19A-AF is a 32-bit ARM Cortex-M4F microcontroller from the SAM D51 family, delivering 120 MHz CPU performance with FPU, 512 KB of dual-panel Flash with ECC, and up to 192 KB SRAM in a 100-pin TQFP (14x14 mm) package. It integrates a high-speed USB 2.0 Full-Speed interface, multiple SERCOM peripherals, a 12-bit 1 MSPS ADC, dual 12-bit DACs, and a Crypto Engine supporting AES, SHA, and True Random Number Generation.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, memory, and programmable peripherals around a common bus. Within the embedded semiconductor taxonomy, MCUs sit below microprocessors (which require external memory) and above basic ASICs in capability. The SAM D51 family is positioned as a high-performance general-purpose MCU, using the ARM Cortex-M4F core with single-precision FPU to accelerate DSP and floating-point control loops. ECC-protected Flash and SRAM target safety-critical and industrial applications where soft-error reliability matters.

Key features of the ATSAMD51N19A-AF include 120 MHz core clock with DSP extensions, 512 KB dual-panel Flash, up to 192 KB SRAM, six SERCOM modules configurable as UART/SPI/I2C, one full-speed USB 2.0 device/host, up to 12-bit 1 MSPS ADC with up to 16 channels, dual 12-bit DACs, four TC capture/compare/PWM channels, and a True Random Number Generator. The device supports 1.62V-3.6V supply and an extended industrial temperature range of -40C to +125C.

Architecturally, the ATSAMD51N19A-AF uses a 5-stage pipeline ARM Cortex-M4F core with single-precision FPU, MPU, and CoreSight debug. The dual-panel Flash allows simultaneous read/write, enabling live firmware updates without CPU stalls. The peripheral event system enables deterministic inter-peripheral signaling without CPU intervention, critical for motor control and power conversion applications.

Typical applications include industrial control (PLC I/O modules, motor drives), IoT edge nodes with secure TLS acceleration, USB peripherals (HID, CDC, composite), human-machine interfaces (HMI) with TFT touch control, audio processing with on-chip DAC, and portable instrumentation. The integrated crypto engine also suits secure-boot and OTA update designs.

When designing with the ATSAMD51N19A-AF, ensure decoupling follows the datasheet reference layout with 100 nF caps at each supply pin and a bulk 4.7 uF cap near the package. The TC and ADC reference grounds must be tied to a low-impedance analog ground plane. Verify the extended temperature option (-AF suffix) matches your application's thermal envelope.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the standalone manufacturer datasheet, providing comparison-ready data for sourcing decisions.

Drop-in alternatives for ATSAMD51N19A-AF β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAMD51N19A-AF (same form factor and footprint) β€” differing in USB, DAC, Package, SRAM, Operating Temperature.

Microchip Technology
USB: USB 2.0 Full-Speed device and host (integrated PHY)
DAC: 10-bit, 300 ksps
Package: 48-pin VQFN (7x7 mm)
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: USB 2.0 Full-Speed with on-chip PHY
DAC: 10-bit, 350 ksps, 2 channels
Package: 64-TQFP (10x10 mm)
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: Full-Speed USB 2.0 with on-chip PHY
DAC: 2x 12-bit, 1 MSPS
Package: 64-QFN (9x9 mm) with exposed pad
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: USB 2.0 Full-Speed with integrated PHY
DAC: 12-bit
Package: 64-VQFN (9x9 mm) with exposed pad
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: HS USB 2.0 Device/Host with on-chip PHY
DAC: 2x 12-bit, 1 MSPS
Package: 64-pin QFN (9x9 mm) with exposed pad
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: USB 2.0 Full Speed with on-chip transceiver
DAC: 12-bit, 2 channels
Package: 100-pin TQFP (14x14 mm), 0.5 mm pitch
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: USB 2.0 Full-Speed with on-chip PHY
SRAM: 256 KB (ECC)
Operating Temperature: -40 C to +125 C (Extended)
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: USB 2.0 Full-Speed, on-chip transceiver
DAC: 12-bit, 1 MSPS
SRAM: 192 KB
Compare with ATSAMD51N19A-AF β†’
Microchip Technology
USB: USB 2.0 Full-Speed Host/Device with on-chip PHY
DAC: 2x 12-bit
SRAM: 192 KB with ECC
Compare with ATSAMD51N19A-AF β†’

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

ATSAMD51N19A-AFT

βœ… Drop-In
Microchip Technology
πŸ“¦ 100-pin TQFP (14x14)
SAM D51 Β· ARM Cortex-M4F Β· 32-Bit Single-Core Β· 120 MHz Β· Yes (single-precision) Β· Yes Β· 512 KB (512K x 8) Β· Yes (Dual-Panel)

βœ“ In Stock

$4.8 / Unit

View Datasheet β†’

ATSAMD51J20A-MF

βœ… Drop-In
Microchip Technology
πŸ“¦ 100-pin TQFP-equivalent (LQFP-100)
ARM Cortex-M4F with FPU and DSP Β· 120 MHz Β· 1 MB (1M x 8) with ECC Β· 256 KB with ECC Β· 1.71 V to 3.6 V Β· 3.3 V typical Β· 64-VQFN (9x9 mm) with exposed pad Β· USB 2.0 Full-Speed with integrated PHY

βœ“ In Stock

$5.2 / Unit

View Datasheet β†’

ATSAMD51J20A-MFT

βœ… Drop-In
Microchip Technology
πŸ“¦ LQFP-100
ARM Cortex-M4F with FPU and DSP instructions Β· 120 MHz Β· 1 MB Flash with ECC (dual-panel) Β· 256 KB with ECC Β· 1.71 V to 3.6 V Β· -40C to +125C (extended industrial) Β· 64-pin QFN (9x9 mm) with exposed pad Β· 12-bit, up to 1 MSPS, 16 channels

βœ“ In Stock

$5.1 / Unit

View Datasheet β†’

ATSAMD51J19A-MF

βœ… Drop-In
Microchip Technology
πŸ“¦ LQFP-100 (pin-compatible SAM D51 family)
ARM Cortex-M4F with FPU Β· 120 MHz Β· 512 KB Β· 192 KB Β· 1.71 V to 3.6 V Β· 12-bit, 1 MSPS Β· 2x 12-bit, 1 MSPS Β· Full-Speed USB 2.0 with on-chip PHY

βœ“ In Stock

$5.4 / Unit

View Datasheet β†’

ATSAMD51J18A-AU-EFP

βœ… Drop-In
Microchip Technology
πŸ“¦ LQFP-100
ARM Cortex-M4F with FPU and DSP Β· 120 MHz Β· 256 KB (256K x 8) with ECC Β· 128 KB with ECC Β· 64-TQFP (10x10 mm) Β· 1.71 V to 3.63 V Β· -40C to +85C Β· 12-bit, up to 1 Msps, up to 16 channels

βœ“ In Stock

$3.95 / Unit

View Datasheet β†’

ATSAMD51G19A-MFT

βœ… Drop-In
Microchip Technology
πŸ“¦ LQFP-100
ARM Cortex-M4F with FPU and DSP instructions Β· 120 MHz Β· 512 KB (dual-panel with ECC) Β· 192 KB (with ECC) Β· 1.71 V to 3.63 V Β· -40C to +125C (extended industrial) Β· 48-pin VQFN (7x7 mm) Β· USB 2.0 Full-Speed device and host (integrated PHY)

βœ“ In Stock

$4.02 / Unit

View Datasheet β†’

ATSAMD51N19A-AF Maximum Ratings & Electrical Characteristics

Core Architecture ARM Cortex-M4F with FPU
Maximum CPU Frequency 120 MHz
Program Flash Memory 512 KB (dual-panel, with ECC)
SRAM 192 KB (with ECC)
Package 100-pin TQFP (14x14 mm)
Operating Voltage 1.62 V to 3.6 V
Operating Temperature -40C to +125C (extended)
ADC 12-bit, up to 1 MSPS
DAC Dual 12-bit
USB USB 2.0 Full-Speed device/host
SERCOM Modules 6 (configurable UART/SPI/I2C)
Crypto Engine AES, SHA, TRNG
Mounting Type Surface Mount
RoHS Status Compliant
MSL Level 3 (168 hours)

ATSAMD51N19A-AF Pin Configuration

TQFP-100 Package Pinout Diagram TQFP-100 14x14mm, P0.5mm, JEDEC MS-026. 1 25 TQFP-100
Pin 1 VDDIO β€” Digital I/O supply voltage
Pin 2 PA00 β€” I/O line A00 (GPIO, analog)
Pin 3 PA01 β€” I/O line A01 (GPIO, analog)
Pin 4 PA02 β€” I/O line A02 (GPIO, analog)
Pin 5 PA03 β€” I/O line A03 (GPIO, analog)
Pin 6 GND β€” Ground
Pin 7 PA04 β€” I/O line A04 (GPIO, analog)
Pin 8 PA05 β€” I/O line A05 (GPIO, analog)
Pin 9 PA06 β€” I/O line A06 (GPIO, analog)
Pin 10 PA07 β€” I/O line A07 (GPIO, analog)
Pin 11 VDDIO β€” Digital I/O supply voltage
Pin 12 PA08 β€” SERCOM0/PAD0 or GPIO
Pin 13 PA09 β€” SERCOM0/PAD1 or GPIO
Pin 14 PA10 β€” SERCOM0/PAD2 or GPIO
Pin 15 PA11 β€” SERCOM0/PAD3 or GPIO
Pin 16 PA12 β€” SERCOM1/PAD0 or GPIO
Pin 17 PA13 β€” SERCOM1/PAD1 or GPIO
Pin 18 PA14 β€” SERCOM1/PAD2 or GPIO
Pin 19 PA15 β€” SERCOM1/PAD3 or GPIO
Pin 20 GND β€” Ground
Pin 21 PA16 β€” SERCOM2/PAD0 or GPIO
Pin 22 PA17 β€” SERCOM2/PAD1 or GPIO
Pin 23 PA18 β€” SERCOM2/PAD2 or GPIO
Pin 24 PA19 β€” SERCOM2/PAD3 or GPIO
Pin 25 PA20 β€” SERCOM3/PAD0 or GPIO
Pin 26 PA21 β€” SERCOM3/PAD1 or GPIO
Pin 27 PA22 β€” SERCOM3/PAD2 or GPIO
Pin 28 PA23 β€” SERCOM3/PAD3 or GPIO
Pin 29 PA24 β€” USB DP or GPIO
Pin 30 PA25 β€” USB DM or GPIO
Pin 31 VDDIO β€” Digital I/O supply voltage
Pin 32 GND β€” Ground
Pin 33 PB00 β€” I/O line B00 (GPIO, analog)
Pin 34 PB01 β€” I/O line B01 (GPIO, analog)
Pin 35 PB02 β€” SERCOM4/PAD0 or GPIO
Pin 36 PB03 β€” SERCOM4/PAD1 or GPIO
Pin 37 PB04 β€” SERCOM4/PAD2 or GPIO
Pin 38 PB05 β€” SERCOM4/PAD3 or GPIO
Pin 39 PB06 β€” SERCOM5/PAD0 or GPIO
Pin 40 PB07 β€” SERCOM5/PAD1 or GPIO
Pin 41 PB08 β€” SERCOM5/PAD2 or GPIO
Pin 42 PB09 β€” SERCOM5/PAD3 or GPIO
Pin 43 GND β€” Ground
Pin 44 PB10 β€” I/O line B10 (GPIO, analog)
Pin 45 PB11 β€” I/O line B11 (GPIO, analog)
Pin 46 PB12 β€” TC0/WO0 or GPIO
Pin 47 PB13 β€” TC0/WO1 or GPIO
Pin 48 PB14 β€” TC1/WO0 or GPIO
Pin 49 PB15 β€” TC1/WO1 or GPIO
Pin 50 PB16 β€” TC2/WO0 or GPIO
Pin 51 PB17 β€” TC2/WO1 or GPIO
Pin 52 VDDIO β€” Digital I/O supply voltage
Pin 53 PB18 β€” I/O line B18 (GPIO, analog)
Pin 54 PB19 β€” I/O line B19 (GPIO, analog)
Pin 55 PB20 β€” I/O line B20 (GPIO, analog)
Pin 56 PB21 β€” I/O line B21 (GPIO, analog)
Pin 57 PB22 β€” I/O line B22 (GPIO, analog)
Pin 58 PB23 β€” I/O line B23 (GPIO, analog)
Pin 59 PB24 β€” I/O line B24 (GPIO, analog)
Pin 60 PB25 β€” I/O line B25 (GPIO, analog)
Pin 61 PC00 β€” I/O line C00 (GPIO, analog)
Pin 62 PC01 β€” I/O line C01 (GPIO, analog)
Pin 63 PC02 β€” I/O line C02 (GPIO, analog)
Pin 64 PC03 β€” I/O line C03 (GPIO, analog)
Pin 65 VDDCORE β€” Core voltage output (LDO)
Pin 66 GND β€” Ground
Pin 67 VDDIN β€” Main voltage regulator input
Pin 68 PC04 β€” I/O line C04 (GPIO, analog)
Pin 69 PC05 β€” I/O line C05 (GPIO, analog)
Pin 70 PC06 β€” I/O line C06 (GPIO, analog)
Pin 71 PC07 β€” I/O line C07 (GPIO, analog)
Pin 72 PC08 β€” SERCOM6/PAD0 or GPIO
Pin 73 PC09 β€” SERCOM6/PAD1 or GPIO
Pin 74 PC10 β€” SERCOM6/PAD2 or GPIO
Pin 75 PC11 β€” SERCOM6/PAD3 or GPIO
Pin 76 PC12 β€” SERCOM7/PAD0 or GPIO
Pin 77 PC13 β€” SERCOM7/PAD1 or GPIO
Pin 78 PC14 β€” SERCOM7/PAD2 or GPIO
Pin 79 PC15 β€” SERCOM7/PAD3 or GPIO
Pin 80 GND β€” Ground
Pin 81 PC16 β€” I/O line C16 (GPIO, analog)
Pin 82 PC17 β€” I/O line C17 (GPIO, analog)
Pin 83 PC18 β€” I/O line C18 (GPIO, analog)
Pin 84 PC19 β€” I/O line C19 (GPIO, analog)
Pin 85 PC20 β€” I/O line C20 (GPIO, analog)
Pin 86 PC21 β€” I/O line C21 (GPIO, analog)
Pin 87 PC22 β€” I/O line C22 (GPIO, analog)
Pin 88 PC23 β€” I/O line C23 (GPIO, analog)
Pin 89 PD00 β€” I/O line D00 (GPIO, analog)
Pin 90 PD01 β€” I/O line D01 (GPIO, analog)
Pin 91 PD02 β€” I/O line D02 (GPIO, analog)
Pin 92 PD03 β€” I/O line D03 (GPIO, analog)
Pin 93 PD04 β€” I/O line D04 (GPIO, analog)
Pin 94 PD05 β€” I/O line D05 (GPIO, analog)
Pin 95 PD06 β€” I/O line D06 (GPIO, analog)
Pin 96 PD07 β€” I/O line D07 (GPIO, analog)
Pin 97 PD08 β€” I/O line D08 (GPIO, analog)
Pin 98 PD09 β€” I/O line D09 (GPIO, analog)
Pin 99 RESET_N β€” Active-low reset input
Pin 100 VDDIO β€” Digital I/O supply voltage

Typical Applications

ATSAMD51N19A-AF is suitable for 6 applications: Industrial Control (PLC I/O Modules, Motor Drives), IoT Edge Nodes with TLS Acceleration, USB Peripherals (HID, CDC, Composite), Human-Machine Interfaces (HMI) with TFT Touch, Audio Processing with On-Chip DAC, Portable Instrumentation and Data Loggers.

🏭

Industrial Control (PLC I/O Modules, Motor Drives)

The ATSAMD51N19A-AF fits industrial PLC and motor-drive applications thanks to its 120 MHz Cortex-M4F core, hardware FPU for field-oriented control, and 192 KB SRAM for control-loop buffers. Its six SERCOM modules can drive UART to operator panels, SPI to gate drivers, and I2C to sensor chains simultaneously. The 12-bit 1 MSPS ADC samples current and voltage feedback accurately, while dual 12-bit DACs generate analog reference signals. Extended -40C to +125C temperature range tolerates factory-floor thermal stress. The integrated crypto engine supports signed firmware for functional-safety designs.

🧩

IoT Edge Nodes with TLS Acceleration

The ATSAMD51N19A-AF suits secure IoT edge nodes because the on-chip crypto engine accelerates AES-128/256 and SHA-2, offloading TLS handshakes from the CPU. The USB 2.0 Full-Speed interface enables direct tethering to gateways, while SERCOM ports interface LoRa, Wi-Fi, or BLE modules. 192 KB SRAM hosts TLS session buffers and MQTT payload queues without external memory. The dual-panel Flash supports secure over-the-air firmware updates. Operating from 1.62V to 3.6V permits direct Li-ion battery connection.

πŸ–₯️

USB Peripherals (HID, CDC, Composite)

The ATSAMD51N19A-AF is ideal for USB peripherals due to its integrated USB 2.0 Full-Speed controller with on-chip transceiver. The Microchip ASF and MPLAB Harmony stacks provide ready-to-use HID, CDC, MSD, and composite class drivers. Cortex-M4F at 120 MHz handles protocol stack and application logic without external MCU support. 512 KB Flash stores composite descriptor tables plus application code. The 100-pin TQFP gives ample I/O for buttons, LEDs, and downstream SPI peripherals in human-interface devices.

πŸ“Ί

Human-Machine Interfaces (HMI) with TFT Touch

The ATSAMD51N19A-AF drives TFT-LCD HMI panels with its high-speed SERCOM channels connecting to SPI-based display controllers. The Cortex-M4F core renders graphics via lightweight LVGL or emWin stacks in 192 KB SRAM. 12-bit ADC reads resistive touch coordinates accurately. The crypto engine secures HMI passwords and operator credentials. Extended temperature range supports outdoor kiosk and industrial panel deployments. Multiple TC channels generate PWM backlight dimming and buzzer tones.

🎧

Audio Processing with On-Chip DAC

The ATSAMD51N19A-AF delivers up to 16-bit audio quality through its dual 12-bit DACs at 1 MSPS, sufficient for voice prompts, alert tones, and simple waveform synthesis. Cortex-M4F DSP extensions accelerate FFT and biquad filtering in real time. SERCOM channels drive external I2S codecs for higher-fidelity paths. 192 KB SRAM buffers multi-second audio chunks without external memory. The USB Full-Speed interface streams 16 kHz audio to host PCs.

✈️

Portable Instrumentation and Data Loggers

The ATSAMD51N19A-AF fits portable instruments because its Cortex-M4F core processes sensor data, the 12-bit ADC digitizes multiple channels at 1 MSPS, and 192 KB SRAM stores acquisition buffers. USB Full-Speed enables real-time data streaming to a host PC. The 1.62V-3.6V supply range supports direct Li-ion battery operation with no external LDO. The crypto engine secures proprietary measurement data on removable media via SD-card interface.

What is the operating voltage of the ATSAMD51N19A-AF?
The ATSAMD51N19A-AF operates from 1.62V to 3.6V on its main VDD supply. According to the Microchip SAM D51 family datasheet (DS60001507E), the core voltage is generated internally by an LDO from VDDIN. Operation below 1.62V violates the brown-out detector threshold and may cause undefined Flash read behavior.
How much Flash and SRAM does the ATSAMD51N19A-AF have?
The ATSAMD51N19A-AF provides 512 KB of dual-panel Flash with single-error-correction ECC and up to 192 KB of SRAM. The dual-panel architecture lets the CPU execute from one bank while the other is being written, enabling live firmware updates without stalling the core.
What is the maximum CPU clock frequency of the ATSAMD51N19A-AF?
The ATSAMD51N19A-AF runs up to 120 MHz on its ARM Cortex-M4F core. With single-precision FPU and DSP extensions, this delivers roughly 150 DMIPS and 1.25 DMIPS/MHz. This clock rate is sufficient for real-time motor control loops, USB audio streaming, and edge sensor fusion.
Where can I download the ATSAMD51N19A-AF datasheet PDF?
The official ATSAMD51N19A-AF datasheet is available as document DS60001507E from Microchip's website at https://ww1.microchip.com/downloads/en/DeviceDoc/60001507E.pdf. It covers the entire SAM D51/E51 family including electrical characteristics, peripheral register maps, and reference schematics.
Is the ATSAMD51N19A-AF RoHS compliant?
Yes, the ATSAMD51N19A-AF is RoHS compliant per its Microchip product page. Lead-free (Pb-free) reflow profiles up to 260C peak are supported, and the part is packaged in MSL-3 moisture sensitivity level that requires dry-pack handling prior to board mounting.
Where can I buy the ATSAMD51N19A-AF online?
The ATSAMD51N19A-AF is in stock at major distributors including DigiKey, Mouser, and LCSC as of 2026-09-21. Octopart lists pricing from 10 distributors in real time. For smaller quantities, LCSC shows a starting price around $2.53 in cut-tape reels.
What is the lead time for the ATSAMD51N19A-AF?
Lead time for the ATSAMD51N19A-AF is typically 8-12 weeks from Microchip factory as of 2026-09-21. Distributor stock at DigiKey and Mouser can reduce this to immediate shipment for small quantities. For volume production orders above 10k units, contact Microchip directly for scheduled orders.
What is the difference between ATSAMD51N19A-AF and ATSAMD51N19A-AFT?
The ATSAMD51N19A-AF ships in tray packaging, while the ATSAMD51N19A-AFT ships in Tape and Reel for high-volume SMT assembly. Both share the same 100-pin TQFP (14x14 mm) package and identical silicon die, so they are fully pin-compatible drop-in replacements differing only in packing media.
How does ATSAMD51N19A-AF compare to ATSAMD51J19A-MF?
The ATSAMD51N19A-AF has 512 KB Flash and 192 KB SRAM in a 100-pin TQFP, while the ATSAMD51J19A-MF has 512 KB Flash and 192 KB SRAM in a 64-pin QFN. Both run the same Cortex-M4F core at 120 MHz. Choose ATSAMD51N19A-AF when you need maximum I/O count, or ATSAMD51J19A-MF for compact PCBs.
Can ATSAME51N19A-AFT replace ATSAMD51N19A-AF?
Yes, the ATSAME51N19A-AFT can serve as a drop-in functional replacement in many applications. The SAM E51 adds an integrated Ethernet MAC and higher-pin-count options, and the ATSAME51N19A-AFT is pin-compatible with the ATSAMD51N19A-AF in TQFP-100. Firmware changes for the Ethernet peripheral may be required.
What is the best drop-in replacement for the ATSAMD51N19A-AF?
The best drop-in replacement is the ATSAMD51N19A-AFT, which shares identical silicon and the 100-pin TQFP (14x14 mm) package with the ATSAMD51N19A-AF, differing only in Tape and Reel packaging. For larger Flash budget, ATSAMD51J20A-MF offers 1 MB Flash in a related SAM D51 variant.
What is the operating temperature range of the ATSAMD51N19A-AF?
The ATSAMD51N19A-AF supports -40C to +125C operating temperature per the -AF suffix ordering code. This extended industrial range is suitable for outdoor, automotive under-hood, and harsh factory-floor environments where commercial-grade 0C-70C parts would fail.
Does the ATSAMD51N19A-AF support USB?
Yes, the ATSAMD51N19A-AF integrates a USB 2.0 Full-Speed (12 Mbps) controller with on-chip transceiver. It supports both device and host modes, and can operate as CDC, HID, MSD, or composite device classes. The Microchip ASF/MPLAB Harmony stacks provide ready-to-use USB class drivers.
Does the ATSAMD51N19A-AF have a floating-point unit?
Yes, the ATSAMD51N19A-AF includes a single-precision IEEE 754 floating-point unit (FPU) integrated into the ARM Cortex-M4F core. The FPU accelerates float math for sensor filtering, FFT, PID control, and audio processing. It also has a Memory Protection Unit for secure task isolation.
What key specifications of ATSAMD51N19A-AF should engineers know?
The ATSAMD51N19A-AF key specifications are: ARM Cortex-M4F core at 120 MHz with FPU; 512 KB dual-panel Flash with ECC; 192 KB SRAM with ECC; 100-pin TQFP 14x14 mm package; 1.62V-3.6V supply; -40C to +125C operating range; six SERCOM peripherals; USB 2.0 Full-Speed device/host; 12-bit 1 MSPS ADC; dual 12-bit DAC; AES/SHA crypto engine. These cover CPU performance, memory architecture, package and electrical envelope, peripherals, and security.

Engineering reference data for ATSAMD51N19A-AF β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAMD51N19A-AF when you need the maximum memory density (512 KB Flash, 192 KB SRAM) within Microchip's TQFP-100 SAM D51 lineup, plus the extended -40C to +125C industrial temperature range. The Tray packaging option makes it ideal for prototyping, pilot runs, and low-volume production. If you need only 256 KB Flash and commercial temperature range, the ATSAMD51J18A-AU is more cost-effective. For larger 1 MB Flash projects, choose the ATSAMD51J20A-MF. For Tape and Reel high-volume assembly, the ATSAMD51N19A-AFT is the pin-compatible production variant. For Ethernet MAC integration, consider migrating to the ATSAME51N19A-AFT which adds 10/100 Ethernet.

Comparison with Alternatives

Parameter This Product ATSAMD51N19A-AFT ATSAMD51J20A-MF ATSAMD51J19A-MF ATSAMD51J18A-AU ATSAMD51G19A-MFT
Package TQFP-100 (14x14 mm) TQFP-100 (14x14 mm) - same LQFP-100 - same footprint family QFN-64 (not pin-compatible) LQFP-100 - same footprint family QFN-48 (not pin-compatible)
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core ARM Cortex-M4F 120 MHz ARM Cortex-M4F 120 MHz ARM Cortex-M4F 120 MHz ARM Cortex-M4F 120 MHz ARM Cortex-M4F 120 MHz ARM Cortex-M4F 120 MHz
Flash 512 KB 512 KB 1024 KB 512 KB 256 KB 512 KB
SRAM 192 KB 192 KB 256 KB 192 KB 128 KB 192 KB
Operating Temperature -40C to +125C -40C to +125C -40C to +125C -40C to +125C -40C to +85C -40C to +125C
USB USB 2.0 Full-Speed USB 2.0 Full-Speed USB 2.0 Full-Speed USB 2.0 Full-Speed USB 2.0 Full-Speed USB 2.0 Full-Speed
Crypto Engine AES, SHA, TRNG AES, SHA, TRNG AES, SHA, TRNG AES, SHA, TRNG AES, SHA, TRNG AES, SHA, TRNG

Key Differentiators

  • Highest memory density in TQFP-100 SAM D51 family at 512 KB Flash + 192 KB SRAM (vs ATSAMD51J18A-AU)
  • Extended -40C to +125C industrial temperature range (vs ATSAMD51J18A-AU)
  • Tray packaging optimized for prototyping and low-volume assembly (vs ATSAMD51N19A-AFT)

Design Notes

Place a 100 nF decoupling capacitor within 2 mm of every VDDIO and VDDIN pin, plus one bulk 4.7 uF ceramic near the package. The internal LDO that generates VDDCORE requires a 1 uF low-ESR output cap on the VDDCORE pin. Routing the analog supply AVVDD through a ferrite bead from VDDIN isolates ADC noise; failure to do this can couple switching noise into ADC measurements and reduce effective ENOB.

The TQFP-100 package has a theta_JA around 50 C/W on a standard 4-layer JEDEC test board. At full CPU load running 120 MHz with all peripherals active, typical dissipation is around 200 mW, yielding a 10C rise above ambient. For industrial -40C to +125C operation, ensure ambient does not push junction above 125C. Wide copper pours beneath exposed pads and on inner layers reduce theta_JA to around 30 C/W.

The ATSAMD51N19A-AF pinout follows the SAM D51 family convention with PAxx/ PBxx/ PCxx/ PDxx ports grouped together and SERCOM alternate functions color-mapped in the datasheet. Maintain continuous ground plane under the MCU to provide low-impedance return paths for SERCOM and USB signals. Route USB DP/DM as a 90 ohm differential pair with length matching within 2 mm. Place the 32.768 kHz crystal within 5 mm of the XIN32/XOUT32 pins to minimize parasitic capacitance.

Do not skip configuring the NVMCTRL peripheral to enable dual-panel Flash and ECC; if left at default single-panel mode, write performance is reduced and ECC errors trigger unwanted NMI. To use USB, the VBUS pin must see 5V through a 10k pull-up divider, and the UDIV clock must be sourced from DFLL or PLL - not from the untrimmed 48 MHz RC. The crypto engine requires the ICache and DMA to be enabled to reach its AES throughput targets.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page. Not AEC-Q100 qualified - for automotive ASIL designs, contact Microchip about ATSAME54/ATSAMV71 AEC-Q100 variants. MSL-3 moisture sensitivity level per JEDEC J-STD-020.

Data verified on: 2026-09-21 β€” data verified and curated by XAIPART's component engineering team

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