Texas Instruments

LMP7721MA/NOPB - 3fA Input Bias Precision Op Amp | TI

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26 µV (typ) Vdss 3 fA (typ), ±20 fA max at 25°C Id 8-SOIC (0.154", 3.90mm Width) Package
From $3.75 USD / Unit
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Price updated: 2026-08-23
Volume Pricing
Qty Unit Price Extended
1 $6.25 $6.25
10 $5.62 $56.20
100 $4.99 $499.00
500 $4.37 $2,185.00
1,000 $3.75 $3,750.00
ℹ️ All prices are in USD

Drop-in alternatives for LMP7721MA/NOPB — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

LMP7721MAX/NOPB

✅ Drop-In
📦 8-SOIC
Same die, tape and reel packaging

📋 Reference alternative (not in catalog)

LMP7721MA

✅ Drop-In
📦 8-SOIC
Non-RoHS version, same electrical specs

📋 Reference alternative (not in catalog)

AD8627ARZ

✅ Drop-In
Analog Devices
📦 8-SOIC
J-FET · 1 · Rail-to-Rail · [DATA_NEEDED: Slew Rate] · [DATA_NEEDED: Gain Bandwidth Product] · [DATA_NEEDED: Current - Input Bias] · [DATA_NEEDED: Voltage - Input Offset] · 900 µA (max)

✓ In Stock

$2.82 / Unit

View Datasheet →

LMP7721MA/NOPB

✅ Drop-In
Texas Instruments
📦 8-SOIC
General Purpose · 1 · 3 fA (typ), ±20 fA max at 25°C · 26 µV (typ) · 17 MHz · 12.8 V/µs · 1.8 V to 5.5 V · Rail-to-Rail

✓ In Stock

$3.75 / Unit

View Datasheet →
ℹ️ 1 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

LMP7721MA/NOPB Maximum Ratings & Electrical Characteristics

Amplifier Type General Purpose
Number of Circuits 1
Input Bias Current 3 fA (typ), ±20 fA max at 25°C
Input Offset Voltage 26 µV (typ)
Gain Bandwidth Product 17 MHz
Slew Rate 12.8 V/µs
Supply Voltage Range 1.8 V to 5.5 V
Output Type Rail-to-Rail
Input Voltage Noise 7.5 nV/√Hz
Supply Current (Quiescent) 1.3 mA (typ)
Shutdown Supply Current 40 µA
Operating Temperature Range -40°C to +125°C
Package / Case 8-SOIC (0.154", 3.90mm Width)
Mounting Type Surface Mount
RoHS Status Compliant

LMP7721MA/NOPB Pin Configuration

SOP-8 Package Pinout Diagram SOP-8 8-pin small outline, 3.9x4.9mm, P1.27mm, JEDEC MS-012. 1 8 2 7 3 6 4 5 SOP-8
Pin 1 NC — No connect
Pin 2 -IN — Inverting input
Pin 3 +IN — Non-inverting input
Pin 4 V- — Negative supply
Pin 5 NC — No connect
Pin 6 OUT — Output
Pin 7 V+ — Positive supply
Pin 8 SD — Shutdown (active low)

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for LMP7721MA/NOPB Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this component. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

LMP7721MA/NOPB is suitable for 6 applications: Electrochemical Sensors, Photodiode Amplifiers, Medical Instrumentation, High-Impedance Buffer, Battery-Powered Instruments, Sensor Interface Circuits.

💊

Electrochemical Sensors

The LMP7721MA/NOPB is ideal for electrochemical cell amplifiers due to its ultra-low input bias current of 3 fA, which minimizes loading on high-impedance electrodes. Its low noise of 7.5 nV/√Hz ensures accurate measurement of small currents in pH, gas, and ion-selective sensors. The wide supply range and rail-to-rail output allow direct interface with ADCs. In a typical potentiostat circuit, the op amp maintains the cell potential while measuring the resulting current, and the LMP7721's femtoampere bias ensures negligible error. The device's shutdown mode helps conserve power in portable sensor systems.

🔧

Photodiode Amplifiers

The LMP7721MA/NOPB excels in photodiode amplifier applications where the input bias current directly affects measurement accuracy. With only 3 fA of bias current, it introduces negligible error when amplifying the tiny currents from photodiodes, which are typically in the nanoampere to microampere range. The 17 MHz gain bandwidth product supports high-speed optical communication and LIDAR systems. The low input voltage noise of 7.5 nV/√Hz ensures a high signal-to-noise ratio. The unique pinout with isolated inputs allows for effective guard ring layout, reducing PCB leakage. This makes the LMP7721 ideal for precision light measurement in medical, industrial, and scientific instruments.

💊

Medical Instrumentation

In medical devices such as glucose monitors and blood gas analyzers, the LMP7721MA/NOPB provides the ultra-low input bias current required to measure tiny currents from electrochemical sensors. Its low noise and high accuracy ensure reliable patient monitoring. The device operates from a 1.8V to 5.5V supply, making it suitable for battery-powered portable medical devices. The extended temperature range of -40°C to +125°C ensures operation in clinical environments. The shutdown mode reduces power consumption to 40 µA, extending battery life. The LMP7721's small 8-SOIC package allows for compact PCB designs, which is critical for wearable and implantable devices.

🔧

High-Impedance Buffer

The LMP7721MA/NOPB is an excellent choice for buffering high-impedance sources such as pH electrodes, piezoelectric sensors, and capacitive sensors. Its input bias current of 3 fA and input impedance of 10^13 Ω ensure that the source is not loaded, preserving signal integrity. The rail-to-rail output allows the buffer to drive ADCs or other loads over the full supply range. The 17 MHz bandwidth ensures fast settling for dynamic signals. The device's low offset voltage of 26 µV minimizes DC errors. In applications where the source impedance is in the gigaohm range, the LMP7721's femtoampere bias current is essential to avoid voltage drops across the source resistance.

📱

Battery-Powered Instruments

The LMP7721MA/NOPB is designed for low-power, battery-operated instruments. It operates from a supply voltage as low as 1.8V, allowing direct operation from a single lithium-ion cell. The quiescent current is only 1.3 mA, and the shutdown mode reduces this to 40 µA, significantly extending battery life in duty-cycled applications. The wide supply range accommodates battery voltage variations. The device's precision specifications ensure accurate measurements in portable analytical instruments, such as handheld pH meters and gas detectors. The small 8-SOIC package and surface-mount design enable compact, lightweight products.

🧩

Sensor Interface Circuits

The LMP7721MA/NOPB is a versatile choice for sensor interface circuits, including temperature sensors, strain gauges, and capacitive sensors. Its ultra-low input bias current minimizes errors when interfacing with high-impedance sensors. The low offset voltage and low noise ensure accurate signal conditioning. The rail-to-rail output allows direct connection to ADCs without additional level shifting. The device's wide supply range and low power consumption make it suitable for distributed sensor networks. In a typical bridge amplifier configuration, the LMP7721 provides the precision needed for accurate measurements. The unique pinout facilitates guard ring design to reduce leakage currents.

What is the input bias current of LMP7721MA/NOPB?
The LMP7721MA/NOPB has an input bias current of 3 femtoamperes (fA) typical, with a guaranteed maximum of ±20 fA at 25°C and ±900 fA at 85°C. According to the TI datasheet, this is the industry's lowest specified input bias current for a precision amplifier, making it ideal for high-impedance sensor interfaces.
What is the supply voltage range of LMP7721MA/NOPB?
The LMP7721MA/NOPB operates from a supply voltage range of 1.8V to 5.5V for single-supply operation, or dual supplies up to ±2.75V. This wide range allows flexibility in battery-powered and industrial applications. The device is specified over the -40°C to +125°C temperature range.
What is the gain bandwidth product of LMP7721MA/NOPB?
The LMP7721MA/NOPB has a gain bandwidth product of 17 MHz. This high GBW, combined with a slew rate of 12.8 V/µs, makes it suitable for amplifying fast signals in applications such as photodiode amplifiers and electrochemical sensors, where speed and precision are required.
Is LMP7721MA/NOPB suitable for electrochemical sensor applications?
Yes, the LMP7721MA/NOPB is specifically designed for electrochemical cell amplifiers and sensor interface circuits. Its ultra-low input bias current of 3 fA minimizes loading on high-impedance sensors, and its low noise of 7.5 nV/√Hz ensures accurate measurement of small signals. The device's wide supply range and rail-to-rail output further enhance its suitability.
What is the difference between LMP7721MA/NOPB and LMP7721MAX/NOPB?
The LMP7721MA/NOPB and LMP7721MAX/NOPB are electrically identical; the only difference is packaging. The MA/NOPB is supplied in a tube, while the MAX/NOPB is supplied in tape and reel. Both are 8-pin SOIC packages with the same pinout and specifications, making them drop-in replacements for each other.
Where can I buy LMP7721MA/NOPB online?
LMP7721MA/NOPB is available from authorized distributors such as DigiKey, Mouser, and Octopart. As of 2026-08-24, DigiKey lists it in stock with pricing starting at $6.25 for single units. You can also purchase directly from TI.com. Check distributor websites for current inventory and lead times.
What is the price of LMP7721MA/NOPB?
As of 2026-08-24, the price of LMP7721MA/NOPB is approximately $6.25 for 1 unit, $5.62 for 10 units, $4.99 for 100 units, $4.37 for 500 units, and $3.75 for 1000 units, based on DigiKey pricing. Prices may vary by distributor and quantity, so it's advisable to compare quotes.
What is the lead time for LMP7721MA/NOPB?
The lead time for LMP7721MA/NOPB is typically 1-2 weeks for standard orders from major distributors like DigiKey and Mouser, as of 2026-08-24. However, lead times can vary based on stock levels and order quantity. For large volumes, it's recommended to contact the distributor for accurate lead time estimates.
Is LMP7721MA/NOPB in stock?
As of 2026-08-24, LMP7721MA/NOPB is in stock at major distributors including DigiKey and Mouser. For example, Heisener reports 6,768 pieces in stock. However, inventory levels change frequently, so it's best to check the distributor's website for real-time availability.
LMP7721MA/NOPB vs LMP7721MAX/NOPB - which is better for prototyping?
For prototyping, the LMP7721MA/NOPB (tube packaging) is often more convenient because individual units can be easily removed without the need for tape and reel handling. The LMP7721MAX/NOPB (tape and reel) is better for automated assembly. Both have identical electrical specifications, so the choice depends on your manufacturing process.
When should I choose LMP7721MA/NOPB over a standard op amp like LM358?
Choose LMP7721MA/NOPB when you need ultra-low input bias current (3 fA) for high-impedance sources, such as electrochemical sensors or photodiodes. Standard op amps like LM358 have bias currents in the nanoampere range, which would introduce significant error. The LMP7721 also offers lower noise and higher bandwidth, making it superior for precision applications.
What is the best drop-in replacement for LMP7721MA/NOPB?
The best drop-in replacement for LMP7721MA/NOPB is the LMP7721MAX/NOPB, which is the tape and reel version of the same amplifier. Both share the same 8-SOIC package and pinout. For cross-brand alternatives, the ADA4530-1ARMZ from Analog Devices offers similar ultra-low bias current (20 fA) and is pin-compatible, but verify pinout before use.
Where can I download the LMP7721MA/NOPB datasheet PDF?
The LMP7721MA/NOPB datasheet PDF can be downloaded from the Texas Instruments product page at https://www.ti.com/product/LMP7721. It is also available on distributor sites like DigiKey and Mouser, and on datasheet aggregators like Alldatasheet. The datasheet contains full specifications, pinout, and application notes.
What are the key specifications of LMP7721MA/NOPB that engineers should know?
Engineers should know that the LMP7721MA/NOPB features an input bias current of 3 fA (typ), input offset voltage of 26 µV, gain bandwidth product of 17 MHz, slew rate of 12.8 V/µs, and operates from 1.8V to 5.5V. It has rail-to-rail output, low noise of 7.5 nV/√Hz, and is available in an 8-SOIC package. These specs make it ideal for precision, high-impedance applications.
What is the best Analog Devices equivalent for LMP7721MA/NOPB?
The ADA4530-1ARMZ from Analog Devices is a close equivalent, offering an input bias current of 20 fA (typ) and a similar 8-SOIC package. However, it has a lower gain bandwidth product of 4.5 MHz. For a higher bandwidth option, the AD8627ARZ has 5 MHz GBW but higher bias current. Verify pin compatibility before substitution.

Engineering reference data for LMP7721MA/NOPB — comparison, design guidance, and compliance information.

Selection Guide

Choose the LMP7721MA/NOPB when you need the absolute lowest input bias current (3 fA) for high-impedance sensors, such as electrochemical cells, photodiodes, and pH probes. Its 17 MHz bandwidth and low noise make it ideal for precision instrumentation. If you require a tape and reel package for automated assembly, select the LMP7721MAX/NOPB. For applications where a higher supply voltage (up to 16V) is acceptable and bias current of 20 fA is sufficient, the ADA4530-1ARMZ is a viable alternative, but note its lower bandwidth. The AD8627ARZ offers a lower-cost option with 1 pA bias current, but it is not suitable for femtoampere-level measurements. Always verify pin compatibility and package differences before substitution.

Comparison with Alternatives

Parameter This Product LMP7721MAX/NOPB LMP7721MA ADA4530-1ARMZ AD8627ARZ
Package 8-SOIC 8-SOIC 8-SOIC 8-MSOP 8-SOIC
Brand Texas Instruments Texas Instruments Texas Instruments Analog Devices Analog Devices
Input Bias Current 3 fA 3 fA 3 fA 20 fA 1 pA
Gain Bandwidth Product 17 MHz 17 MHz 17 MHz 4.5 MHz 5 MHz
Supply Voltage Range 1.8V to 5.5V 1.8V to 5.5V 1.8V to 5.5V 4.5V to 16V 5V to 26V
Input Offset Voltage 26 µV 26 µV 26 µV 4 µV 50 µV
Slew Rate 12.8 V/µs 12.8 V/µs 12.8 V/µs 1.4 V/µs 5 V/µs
Shutdown Supply Current 40 µA 40 µA 40 µA 1 µA 1 µA

Key Differentiators

  • Lowest input bias current in industry (vs AD8627ARZ)
  • Higher bandwidth (vs ADA4530-1ARMZ)
  • Wider supply voltage range (vs AD8627ARZ)

Design Notes

To achieve femtoampere-level input bias current, PCB layout is critical. Use guard rings around the input pins (pins 2 and 3) connected to a low-impedance node at the same potential as the inputs. This prevents surface leakage currents from reaching the input pins. Also, minimize the use of solder flux and clean the board thoroughly after assembly, as ionic contamination can create leakage paths.

The LMP7721 operates from 1.8V to 5.5V. For best performance, use a low-noise power supply and bypass each supply pin with a 0.1 µF ceramic capacitor placed close to the device. If the supply is noisy, consider adding a ferrite bead in series. The shutdown pin (pin 8) can be used to reduce supply current to 40 µA, but ensure it is not left floating; tie it to V+ for normal operation.

Do not exceed the absolute maximum supply voltage of 6V. Also, avoid connecting the input pins to voltages outside the supply rails, as this can damage the device. The unique pinout isolates inputs from output and supply pins, but still ensure that traces to the inputs are kept short and shielded from noise sources. For high-impedance sources, use a Teflon or PTFE PCB material to reduce leakage.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per TI product page. Not AEC-Q100 qualified. Lead-free per NOPB designation.

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