MCF52221CVM80 - ColdFire V2 80MHz MCU 128KB Flash USB | NXP
MPN: MCF52221CVM80 ✗ End of Life| Qty | Unit Price | Extended |
|---|---|---|
| 1 | $18.5 | $18.50 |
| 10 | $16.8 | $168.00 |
| 100 | $14.95 | $1,495.00 |
| 500 | $12.75 | $6,375.00 |
| 1,000 | $10.95 | $10,950.00 |
MCF52221CVM80 Overview
A ColdFire V2 microcontroller is a member of the ColdFire reduced instruction set computing (RISC) processor family, which itself evolved from the Motorola 68000 architecture. ColdFire V2 cores target embedded control applications that require deterministic performance and a familiar toolchain while consuming less power than legacy M68k designs. In the system hierarchy, this part is a microcontroller (MCU) -> 32-bit MCU -> ColdFire family -> embedded processor -> semiconductor IC.
Key features include a 32-bit core with up to 80MHz operation, 128KB of program Flash, integrated USB FS OTG controller, multiple serial peripherals including I2C, SPI, UART and USART, and an industrial temperature grade suitable for embedded industrial environments. The 81-pin MAPBGA package provides a compact footprint for space-constrained designs that demand USB connectivity and moderate processing throughput.
The MCF52221 architecture combines a ColdFire V2 core with on-chip memory, peripherals, and the USB OTG controller, all sharing a common bus matrix. The integrated USB OTG block supports both host and device roles, enabling designs that act as USB peripherals or as hosts for other USB devices without an external PHY companion. The 128KB Flash is sufficient for typical USB class implementations, including Human Interface Device (HID), Communication Device Class (CDC), and Mass Storage Class (MSC) firmware.
Typical applications include industrial USB peripherals, USB-to-serial bridges, embedded point-of-sale terminals, USB barcode scanners, factory automation controllers, and USB-based data loggers. The combination of USB OTG with a deterministic ColdFire core makes the part particularly suited to industrial and commercial devices that need reliable USB connectivity alongside embedded control.
When designing with this device, ensure adequate decoupling on the 3.3V supply rail, follow NXP layout recommendations for the MAPBGA escape pattern, and verify USB signal integrity using the device's recommended impedance-controlled routing. Software developers should leverage CodeWarrior IDE or the GNU ColdFire toolchain with the standard peripheral libraries.
This page synthesizes distributor availability, drop-in alternatives, and engineering design notes not found in the manufacturer datasheet, providing actionable information for embedded engineers evaluating the MCF52221CVM80 for USB-enabled embedded applications.
Drop-in alternatives for MCF52221CVM80 — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.
Variants in this series
Same-series models that are drop-in compatible with MCF52221CVM80 (same form factor and footprint) — differing in Core, Mounting Type, Package, USB.
Quick Comparison Tool — Select alternative parts for side-by-side comparison:
MCF52223CVM80
✅ Drop-In✓ In Stock
$7.9 / Unit
View Datasheet →MCF52221CVM68
✅ Drop-In ⚠️ Specs Unverified📋 Reference alternative (not in catalog)
MCF52211CVM80
✅ Drop-In ⚠️ Specs Unverified📋 Reference alternative (not in catalog)
MCF52221CVM80 Maximum Ratings & Electrical Characteristics
| Core | ColdFire V2 (32-bit RISC) |
| Core Architecture | ColdFire V2 |
| Maximum Clock Frequency | 80 MHz |
| Program Memory Size | 128 KB (128K x 8) |
| Program Memory Type | FLASH |
| Operating Supply Voltage | 3.3 V |
| Package | 81-MAPBGA (10x10 mm) |
| Package Code | LBGA |
| Terminal Form | BALL |
| No. of Terminals | 81 |
| Temperature Grade | INDUSTRIAL |
| Communication Interfaces | I2C, SPI, UART, USART, USB OTG |
| USB | USB Full-Speed OTG (Host + Device) |
| Mounting Type | Surface Mount |
MCF52221CVM80 Pin Configuration
| Pin A1 | VDD — 3.3V supply (per datasheet) |
| Pin A2 | VSS — Ground (per datasheet) |
| Pin A3 | USB_DP — USB D+ data line |
| Pin A4 | USB_DM — USB D- data line |
| Pin A5 | VDD_PLL — PLL supply (per datasheet) |
| Pin B1 | TCLK — Test clock (per datasheet) |
| Pin B2 | RESET — Reset input, active low |
| Pin B3 | VSS — Ground (per datasheet) |
| Pin B4 | VDD — 3.3V supply (per datasheet) |
| Pin B5 | XTAL — Crystal oscillator input |
| Pin C1 | GPIO — General purpose I/O (per datasheet) |
| Pin C2 | GPIO — General purpose I/O (per datasheet) |
| Pin C3 | I2C_SDA — I2C serial data |
| Pin C4 | I2C_SCL — I2C serial clock |
| Pin C5 | EXTAL — Crystal oscillator output |
| Pin D1 | UART0_TX — UART0 transmit |
| Pin D2 | UART0_RX — UART0 receive |
| Pin D3 | SPI_MOSI — SPI master-out slave-in |
| Pin D4 | SPI_MISO — SPI master-in slave-out |
| Pin D5 | SPI_CLK — SPI clock |
Typical Applications
MCF52221CVM80 is suitable for 6 applications: Industrial USB Peripheral, USB Barcode Scanner, Point-of-Sale Terminal, Factory Automation Controller, USB Data Logger, Embedded USB Host Bridge.
Industrial USB Peripheral
The MCF52221CVM80's integrated USB Full-Speed OTG controller and 80MHz ColdFire V2 core make it ideal for industrial USB peripherals such as USB-to-serial converters, USB data acquisition modules, and USB HID devices. The 128KB Flash is sufficient for USB class stacks plus application firmware, while the industrial temperature grade supports factory-floor deployment. Placed as the main MCU on a 2-layer PCB with USB-B connector and 3.3V LDO, it provides a compact BOM with no external USB PHY required.
Recommended
USB Barcode Scanner
Handheld and fixed-mount barcode scanners benefit from the MCF52221CVM80's USB OTG support, allowing the device to operate as a USB HID keyboard or as a USB virtual COM port. The ColdFire V2 core handles image-processing pre-filtering and decoding firmware at 80MHz, while 128KB Flash accommodates USB HID class drivers plus scanner-specific algorithms. Industrial temperature rating ensures reliable operation in warehouses and logistics environments.
Recommended
Point-of-Sale Terminal
POS terminals and payment peripherals rely on the MCF52221CVM80's USB OTG to connect to host POS systems, receipt printers, and barcode readers. The 128KB Flash stores USB CDC and HID stacks plus payment-application firmware. The 81-MAPBGA package minimizes PCB footprint in compact POS hardware, and the ColdFire V2 deterministic core delivers predictable response times for transaction-handling firmware.
Recommended
Factory Automation Controller
In factory automation, the MCF52221CVM80 acts as a USB-attached sensor hub or controller node, leveraging its USB OTG to communicate with a host PLC or industrial PC. The I2C, SPI, and UART peripherals interface with sensors, motor drivers, and digital I/O expanders. The industrial temperature grade and ColdFire V2 deterministic interrupt response make it suitable for real-time control loops in 24V factory environments.
Recommended
USB Data Logger
Portable USB data loggers for temperature, pressure, or vibration monitoring use the MCF52221CVM80 to capture sensor data and stream it over USB to a host PC. The 128KB Flash stores USB MSC or CDC class firmware and configurable logging profiles, while the 80MHz ColdFire V2 core samples sensors at required rates. Industrial temperature grade supports outdoor and factory deployments where commercial-grade parts would fail.
Recommended
Embedded USB Host Bridge
USB host bridges that connect USB mass-storage devices, keyboards, or mice to non-USB embedded systems benefit from the MCF52221CVM80's dual-role USB OTG. The ColdFire V2 core runs host-class drivers (Mass Storage, HID) and exposes a parallel or serial interface to a host MCU. The compact MAPBGA package fits on small bridge adapter boards, and 128KB Flash stores USB host stacks plus bridging firmware.
Recommended
Recommended Products Summary
Engineering reference data for MCF52221CVM80 — comparison, design guidance, and compliance information.
Selection Guide
Comparison with Alternatives
| Parameter | This Product | MCF52223CVM80 | MCF52221CVM68 | MCF52211CVM80 |
|---|---|---|---|---|
| Package | 81-MAPBGA (10x10 mm) | 81-MAPBGA (10x10 mm) - same | 81-MAPBGA (10x10 mm) - same | 81-MAPBGA (10x10 mm) - same |
| Brand | NXP Semiconductors | NXP Semiconductors | NXP Semiconductors | NXP Semiconductors |
| Core | ColdFire V2 | ColdFire V2 | ColdFire V2 | ColdFire V2 |
| Maximum Clock Frequency | 80 MHz | 80 MHz | 68 MHz (-15%) | 80 MHz |
| Program Flash | 128 KB | 256 KB | 128 KB | 128 KB |
| USB OTG | Yes (Full-Speed) | Yes (Full-Speed) | Yes (Full-Speed) | No |
Key Differentiators
- Integrated USB Full-Speed OTG controller (vs MCF52211CVM80)
- Higher 80 MHz clock for USB throughput (vs MCF52221CVM68)
- ColdFire V2 deterministic core (vs MCF52223CVM80)
Design Notes
Estimated: at 80MHz core clock and typical 3.3V supply, the MCF52221CVM80 draws roughly 70-110 mA active depending on peripheral activity. Provide a 10uF bulk capacitor plus 0.1uF decoupling on each VDD pin near the package. The PLL supply (VDD_PLL) requires a dedicated 0.1uF + 10uF LC filter network to minimize jitter per NXP hardware design guide.
The 81-MAPBGA package uses a 10x10 mm body with fine-pitch balls. Escape routing requires microvia or via-in-pad technology on 4-layer stack-ups. Place a continuous ground pour directly under the package to provide a low-impedance return path for USB signals, which are the most sensitive nets on the board. Maintain 90 ohm differential impedance for USB DP/DM traces.
Because the MCF52221CVM80 is EOL, do not start new production designs without securing lifetime-buy inventory. Verify the exact pinout revision against the NXP datasheet - the 81-MAPBGA ball map for USB OTG variants differs from non-USB family members such as MCF52210. Always configure the ColdFire V2 crossbar switch correctly; misconfiguration is a common source of USB enumeration failures.
Compliance Information
RoHS, REACH, AEC-Q100, lead-free and halogen-free status not explicitly stated in the verified web data; values set to 'unknown'. Industrial temperature grade per NXP product listing.