MK22DX256VMC5 - 50MHz Cortex-M4 MCU, 256KB Flash | NXP MK22DX256VMC5 by NXP Semiconductors - electronic component
NXP Semiconductors

MK22DX256VMC5 - 50MHz Cortex-M4 MCU, 256KB Flash | NXP

MPN: MK22DX256VMC5 ✓ Active
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1.71 V to 3.6 V Vdss 121-MAPBGA (8x8 mm) Package 50 MHz Speed 256 KB (256K x 8) Memory
From $5.21 USD / Unit
MOQ: 1 |
Price updated: 2026-10-05
Volume Pricing
Qty Unit Price Extended
1 $8.92 $8.92
10 $7.95 $79.50
100 $6.78 $678.00
500 $5.92 $2,960.00
1,000 $5.21 $5,210.00
ℹ️ All prices are in USD
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MK22DX256VMC5 Overview

The NXP MK22DX256VMC5 is a 32-bit ARM Cortex-M4 microcontroller from the Kinetis K22 sub-family, operating at up to 50 MHz with 256 KB of program Flash and 32 KB of SRAM. It is packaged in a 121-pin MAPBGA (8x8 mm) and supports 1.8 V, 2.5 V, and 3.3 V I/O rails, making it suitable for cost-sensitive industrial and consumer applications requiring USB connectivity, low power, and mid-range memory density.

What is a Cortex-M4 microcontroller? An ARM Cortex-M4 microcontroller is a 32-bit RISC processor core designed for embedded applications that require deterministic real-time response, low power consumption, and rich digital signal processing capability via single-precision FPU and DSP instructions. Within the broader taxonomy, the MK22DX256VMC5 belongs to the Kinetis family of general-purpose MCUs, which itself sits under NXP's LPC/Kinetis portfolio of ARM-based microcontrollers for industrial and IoT use cases. The K22 sub-family specifically targets applications that need low-power operation, processing efficiency, and moderate memory density with integrated USB.

Key features include a 50 MHz Cortex-M4 core with single-precision FPU and DSP extensions, 256 KB Flash, 32 KB SRAM, full-speed USB 2.0 device/host/OTG controller, multiple low-power modes with sub-µA RTC operation, a 16-bit SAR ADC, 12-bit DAC, programmable delay block, multiple timers (FTM, PIT, LPTMR, RTC), and a wide operating voltage range of 1.71 V to 3.6 V. Peripherals include I2C, UART, SPI, I2S, and an on-chip 1 kHz LPO oscillator.

The MK22DX256VMC5 uses a Cortex-M4 core with a 3-stage pipeline, hardware multiply/divide, and a single-precision FPU. Flash is organized in a 256K x 8 array with 16-byte minimum erase sector, supporting in-application programming. The device integrates an 8-channel DMA controller for offloading CPU transfers and a memory protection unit for reliable RTOS operation.

Typical applications include USB HID peripherals, USB-to-UART bridges, low-power sensor hubs, fitness wearables, point-of-sale terminals, building automation controllers, and battery-powered industrial sensors. The integrated full-speed USB with on-chip transceiver simplifies USB device designs without an external PHY.

When designing with the MK22DX256VMC5, ensure proper decoupling on all VDD pins (typically 100 nF + bulk capacitors) and follow NXP's recommended 121-MAPBGA routing escape. The full-speed USB pins D+ and D require 33 ohm series termination and a 1.5 kohm pull-up on D+ for full-speed device operation. For low-power RTC retention, VBAT must be supplied when VDD is removed.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet alone.

Drop-in alternatives for MK22DX256VMC5 — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

MK22DX256VMC5R

✅ Drop-In
📦 121-MAPBGA (8x8 mm)
same 50 MHz speed grade, same 256KB Flash, tape-and-reel packaging variant

📋 Reference alternative (not in catalog)

MK22DX256VMC7

✅ Drop-In
📦 121-MAPBGA (8x8 mm)
72 MHz max CPU vs 50 MHz (+44%), same 256KB Flash and 32KB SRAM, same K22 sub-family peripherals

📋 Reference alternative (not in catalog)

MK22DX128VMC5

✅ Drop-In
📦 121-MAPBGA (8x8 mm)
128KB Flash vs 256KB (-50%), same 50 MHz, same 32KB SRAM, same USB and peripherals

📋 Reference alternative (not in catalog)

MK22DN512VMC5

✅ Drop-In
📦 121-MAPBGA (8x8 mm)
512KB Flash vs 256KB (+100%), same 50 MHz, same 32KB SRAM, same K22 sub-family peripherals

📋 Reference alternative (not in catalog)

MK22FX512VMC5

✅ Drop-In
📦 121-MAPBGA (8x8 mm)
512KB Flash + 128KB SRAM vs 256KB + 32KB, K22F sub-family with enhanced peripherals, pin-to-pin compatible

📋 Reference alternative (not in catalog)

MK22DX256VMC5 Maximum Ratings & Electrical Characteristics

Core Architecture ARM Cortex-M4 with FPU and DSP
Maximum CPU Frequency 50 MHz
Program Flash 256 KB (256K x 8)
SRAM 32 KB
Package 121-MAPBGA (8x8 mm)
Supply Voltage 1.71 V to 3.6 V
I/O Voltage Rails 1.8 V / 2.5 V / 3.3 V
USB Controller USB 2.0 Full-Speed Device/Host/OTG with on-chip PHY
ADC 16-bit SAR ADC
DAC 12-bit DAC
Operating Temperature -40C to +105C
DMA Channels 8 channels
Mounting Type Surface Mount
RoHS Status Compliant
MSL Level 3 (168 hours)

MK22DX256VMC5 121-mapbga (8x8 mm) Pin Configuration Guide

Pin configuration for MK22DX256VMC5 (121-mapbga (8x8 mm) package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

121-mapbga (8x8 mm) package pinout diagram for MK22DX256VMC5

No detailed pinout data available for MK22DX256VMC5.

Refer to the datasheet for full pin configuration.

Typical Applications

MK22DX256VMC5 is suitable for 6 applications: USB HID Peripheral Devices, USB-to-UART Bridge Module, Low-Power Industrial Sensor Hub, Building Automation Controller, Point-of-Sale Terminal, Fitness Wearable Data Logger.

🖥️

USB HID Peripheral Devices

The MK22DX256VMC5 fits USB HID applications because it integrates a USB 2.0 Full-Speed controller with on-chip transceiver, 50 MHz Cortex-M4 processing headroom, and 256 KB Flash to hold USB stacks plus application logic. Placed as the only MCU on the PCB with a USB connector, 33 ohm series termination, and 1.5 kohm pull-up on D+, the part eliminates the need for an external PHY. Compared to discrete USB controllers plus an 8-bit MCU, this part reduces BOM and PCB area while delivering 32 KB SRAM for HID report buffers.

Recommended

MK22DX256VMC7 (Higher-speed drop-in variant) MK22DX256VMC5R (Tape-and-reel production variant)
🌐

USB-to-UART Bridge Module

For USB-to-UART bridges, the MK22DX256VMC5 provides integrated USB device controller plus three UART modules in a single chip. The 50 MHz Cortex-M4 easily handles USB CDC-ACM enumeration at Full-Speed and UART baud rates up to 1 Mbaud. With 256 KB Flash, manufacturers can include vendor-specific command sets and in-field DFU bootloaders without external memory. Compared to FTDI-style discrete bridges, this MCU enables firmware-customizable behavior at lower cost in moderate volumes.

Recommended

MK22DN512VMC5 (Higher-memory variant for richer firmware) MK22DX128VMC5 (Cost-down variant for simpler bridges)
🏭

Low-Power Industrial Sensor Hub

The MK22DX256VMC5 fits low-power sensor hubs because of its multiple low-power modes including VLLS0/1/3 with sub-µA RTC retention and VBAT domain backup. The 16-bit SAR ADC, 12-bit DAC, and multiple I2C/SPI instances allow direct connection to environmental sensors. With 32 KB SRAM, the part buffers sensor data while the Cortex-M4 sleeps between acquisitions. The 1.71-3.6 V supply range supports both 3.3 V and 1.8 V sensor rails without level shifters.

Recommended

MK22FX512VMC5 (Enhanced K22F variant with more peripherals) MK22DX256VMC7 (Higher-speed variant for fast DSP processing)
🏭

Building Automation Controller

For building automation, the MK22DX256VMC5 offers USB for commissioning, multiple UARTs for Modbus or KNX gateways, and 256 KB Flash to host application logic, wireless stacks, and OTA bootloaders. The 50 MHz core executes real-time control loops while DMA offloads peripheral transfers. The -40C to +105C industrial temperature range and integrated RTC with calendar function support unattended operation in basements, mechanical rooms, and outdoor enclosures.

Recommended

MK22DN512VMC5 (More memory for richer OTA and stack libraries) MK22DX256VMC5R (Tape-and-reel production variant)
💳

Point-of-Sale Terminal

The MK22DX256VMC5 fits point-of-sale (POS) terminals because of its USB device port for PC tethering, multiple UART/SPI peripherals for barcode scanners and printers, and the 16-bit ADC for battery monitoring. The 50 MHz Cortex-M4 with FPU accelerates payment protocol parsing and LCD refresh tasks. The 256 KB Flash holds USB stack, application UI, and security primitives, while 32 KB SRAM supports display framebuffers and transaction buffers.

Recommended

MK22DX256VMC7 (Higher-speed variant for faster transactions) MK22FX512VMC5 (Higher-memory K22F variant)
📱

Fitness Wearable Data Logger

The MK22DX256VMC5 suits fitness wearables because of its low-power modes, 16-bit ADC for biometric sensor reading, integrated RTC for time-stamping, and 32 KB SRAM for sample buffering during sleep. The 50 MHz Cortex-M4 with DSP extensions handles real-time heart-rate and step-count algorithms. With 256 KB Flash, firmware can include proprietary algorithms and BLE-over-UART passthrough protocols without external storage. The VBAT domain enables RTC retention during battery swaps.

Recommended

MK22DX128VMC5 (Lower-memory cost-down variant) MK22DX256VMC5R (Production tape-and-reel variant)

Recommended Products Summary

MK22DX256VMC7 Higher-speed drop-in variant Used in: USB HID Peripheral Devices, Low-Power Industrial Sensor Hub, Point-of-Sale Terminal MK22DX256VMC5R Tape-and-reel production variant Used in: USB HID Peripheral Devices, Building Automation Controller, Fitness Wearable Data Logger MK22DN512VMC5 Higher-memory variant for richer firmware Used in: USB-to-UART Bridge Module, Building Automation Controller MK22DX128VMC5 Cost-down variant for simpler bridges Used in: USB-to-UART Bridge Module, Fitness Wearable Data Logger MK22FX512VMC5 Enhanced K22F variant with more peripherals Used in: Low-Power Industrial Sensor Hub, Point-of-Sale Terminal
What is the maximum CPU clock frequency of MK22DX256VMC5?
The MK22DX256VMC5 operates at a maximum CPU frequency of 50 MHz. According to the NXP K22 sub-family datasheet, the Cortex-M4 core runs from the system oscillator with a default 2 MHz FLL reference. Engineers should configure SIM_CLKDIV1 to set the core/system clock divider per the reference manual for the target 50 MHz operation.
How much Flash and SRAM does MK22DX256VMC5 have?
The MK22DX256VMC5 integrates 256 KB of program Flash organized as 256K x 8 with a 16-byte minimum erase sector, and 32 KB of SRAM. Flash supports in-application programming, and the SRAM can be retained in low-leakage stop modes. This density is well matched to mid-range USB-enabled sensor and control applications.
Does MK22DX256VMC5 include a USB controller?
Yes, the MK22DX256VMC5 includes a USB 2.0 Full-Speed controller with on-chip transceiver supporting device, host, and OTG modes. The on-chip PHY eliminates the need for an external USB transceiver, simplifying PCB design. A 33 ohm series termination and 1.5 kohm pull-up on D+ are still required per the NXP hardware design guide.
What package does MK22DX256VMC5 use?
The MK22DX256VMC5 is housed in a 121-pin MAPBGA package measuring 8x8 mm. The MAPBGA has a 0.5 mm ball pitch, which requires 4-layer PCB design with microvia or via-in-pad escape for reliable manufacturing. The package is moisture-sensitive level 3 (MSL3) with a 168-hour floor-life after opening the dry-pack bag.
What is the operating voltage range of MK22DX256VMC5?
The MK22DX256VMC5 operates from 1.71 V to 3.6 V across the full -40C to +105C industrial temperature range. The device supports 1.8 V, 2.5 V, and 3.3 V I/O rails, and includes an integrated voltage regulator that derives the core logic supply from VDD. A separate VBAT pin powers the RTC domain during VDD loss for RTC retention.
Where can I buy MK22DX256VMC5 online?
The MK22DX256VMC5 is in stock at DigiKey (SKU 4800171) and Mouser (NXP Semiconductors). As of 2026-10-06, distributor pricing starts around $8.92 in single-piece quantity with break-prices at 10, 100, 500, and 1000 units. NXP authorized distributors also offer tape-and-reel packaging for high-volume assembly. Lead time for non-stocked reels is typically 8-12 weeks from the factory.
What is the lead time for MK22DX256VMC5?
Lead time for the MK22DX256VMC5 is typically stock to 12 weeks as of 2026-10-06. DigiKey and Mouser usually keep the part in stock in cut-tape and full-reel formats. For multi-thousand-piece orders, contacting NXP directly or through an authorized distributor will yield the most accurate factory lead-time quote.
Is MK22DX256VMC5 in stock at major distributors?
Yes, the MK22DX256VMC5 is listed as in stock at DigiKey (4800171), Mouser, and several franchised distributors as of 2026-10-06. Octopart aggregates 5+ distributors and shows live inventory and pricing. For volumes above 5,000 pieces, contact NXP directly to confirm factory allocation.
MK22DX256VMC5 vs MK21DX256VMC5 - which is better for low-power designs?
The MK22DX256VMC5 (K22 family) is generally preferred over the MK21DX256VMC5 (K21 family) for new low-power designs because the K22 adds enhanced low-power modes, deeper sleep states, and a richer peripheral set at similar pricing. Both share the same 121-MAPBGA package and ARM Cortex-M4 architecture. The K22 also supports wider 1.71-3.6 V supply and offers improved RTC domain power management.
MK22DX256VMC5 vs MK22FN512CBP12R - what is the difference?
The MK22DX256VMC5 is a 50 MHz K22 part with 256 KB Flash in 121-MAPBGA, while the MK22FN512CBP12R is a higher-end 100 MHz K22 part with 512 KB Flash and 128 KB SRAM in a different package. For applications needing more CPU headroom and memory, the FN512 is preferable. For cost-sensitive designs that stay within 50 MHz and 256 KB, the MK22DX256VMC5 provides significant cost savings.
When should I choose MK22DX256VMC5 over MK22DX128VMC5?
Choose MK22DX256VMC5 when your firmware image exceeds 128 KB Flash, when you need a larger application with USB stack and protocol buffers, or when you want code-space headroom for future features. The MK22DX128VMC5 is sufficient for compact USB HID or simple sensor hub designs. Both share the same 121-MAPBGA package and are pin-compatible, so PCB footprint reuse is straightforward.
What is the best drop-in replacement for MK22DX256VMC5?
The best drop-in replacement for the MK22DX256VMC5 in the same 121-MAPBGA package is the MK22DX256VMC7, which offers a higher 72 MHz CPU frequency, 256 KB Flash, and 32 KB SRAM with full pin compatibility. For the same 50 MHz speed grade with identical Flash and SRAM, the MK22DX256VMC5R is a tape-and-reel variant. Both replacements share the same K22 sub-family peripheral set.
Can MK22DX128VMC5 replace MK22DX256VMC5 in existing designs?
The MK22DX128VMC5 is pin-compatible with the MK22DX256VMC5 in the same 121-MAPBGA package, but it has only 128 KB Flash versus 256 KB. If your firmware fits in 128 KB, the MK22DX128VMC5 can serve as a cost-down replacement. If firmware exceeds 128 KB, code size must be reduced before swapping. SRAM (32 KB), peripherals, and 50 MHz CPU speed are identical.
Where to download MK22DX256VMC5 datasheet PDF?
The MK22DX256VMC5 datasheet is available on NXP's official website at https://www.nxp.com/docs/en/data-sheet/K22P64M50SF0.pdf. Additional documentation including the K22 reference manual and application notes can be found on the K22 product page. Pinout information, signal multiplexing, and electrical characteristics are all covered in the datasheet.
Where can I find MK22DX256VMC5 pinout information?
The MK22DX256VMC5 pinout for the 121-MAPBGA package is documented in the NXP K22 sub-family datasheet, specifically in the pinout chapter and signal-multiplexing tables. Each GPIO pin has multiple alternate functions (UART, I2C, SPI, FTM, ADC channels) selected via the PORTx_PCRn registers. Kinetis Design Studio or MCUXpresso IDE can auto-generate pinmux configuration tools for the device.
What are the key specifications of MK22DX256VMC5 that engineers should know?
Engineers evaluating the MK22DX256VMC5 should focus on these key specs: 50 MHz ARM Cortex-M4 core with FPU, 256 KB Flash, 32 KB SRAM, USB 2.0 Full-Speed with on-chip PHY, 1.71 V to 3.6 V supply, 16-bit SAR ADC, 12-bit DAC, 121-MAPBGA 8x8 mm package, and -40C to +105C industrial temperature range. The device also features 8-channel DMA, multiple low-power modes, and integrated RTC with VBAT domain retention.
What is the best NXP equivalent for MK22DX256VMC5 if stock is unavailable?
If the MK22DX256VMC5 is unavailable, the best NXP equivalents in the same 121-MAPBGA footprint are the MK22DX256VMC7 (72 MHz speed grade) and the MK22DN512VMC5 (512 KB Flash variant). For an enhanced alternative with more peripherals, consider the MK22FN512VMC5 from the K22F sub-family. All three parts share the same K22 architecture and pinout, enabling seamless substitution with potential firmware reconfiguration.

Engineering reference data for MK22DX256VMC5 — comparison, design guidance, and compliance information.

Selection Guide

Choose the MK22DX256VMC5 for cost-sensitive USB peripheral and sensor hub designs that fit within 256 KB Flash and 50 MHz CPU performance. The integrated USB 2.0 Full-Speed controller with on-chip PHY makes it ideal for USB-to-UART bridges, HID devices, and PC-tethered peripherals. For designs that exceed 256 KB Flash or need faster CPU, step up to the MK22DN512VMC5 or MK22DX256VMC7 (72 MHz) - both share the same 121-MAPBGA footprint. For cost-down projects where 128 KB Flash is sufficient, the MK22DX128VMC5 offers direct substitution. All K22 sub-family variants share the same peripheral set, toolchain support (MCUXpresso IDE), and SDK, simplifying firmware portability across the family.

Comparison with Alternatives

Parameter This Product MK22DX256VMC5R MK22DX256VMC7 MK22DX128VMC5 MK22DN512VMC5 MK22FX512VMC5
Brand NXP Semiconductors NXP Semiconductors NXP Semiconductors NXP Semiconductors NXP Semiconductors NXP Semiconductors
Package 121-MAPBGA (8x8 mm) 121-MAPBGA (8x8 mm) - same 121-MAPBGA (8x8 mm) - same 121-MAPBGA (8x8 mm) - same 121-MAPBGA (8x8 mm) - same 121-MAPBGA (8x8 mm) - same
Maximum CPU Frequency 50 MHz 50 MHz 72 MHz 50 MHz 50 MHz 120 MHz
Program Flash 256 KB 256 KB 256 KB 128 KB 512 KB 512 KB
SRAM 32 KB 32 KB 32 KB 32 KB 64 KB 128 KB
USB Controller USB 2.0 FS with on-chip PHY USB 2.0 FS with on-chip PHY USB 2.0 FS with on-chip PHY USB 2.0 FS with on-chip PHY USB 2.0 FS with on-chip PHY USB 2.0 FS/HS with on-chip PHY
Supply Voltage 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V
Core Architecture ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU

Key Differentiators

  • Higher CPU speed grade option in same footprint (vs MK22DX256VMC7)
  • Larger memory variant for richer firmware (vs MK22DN512VMC5)
  • Pin-compatible cost-down variant (vs MK22DX128VMC5)

Design Notes

The MK22DX256VMC5 has multiple VDD pins (VDD, VDDIO, VDDA) that each require a 100 nF decoupling capacitor placed as close to the pin as possible, plus a 4.7 uF bulk capacitor near the MCU. A separate 1 uF decoupling cap is recommended for VDDA to isolate analog reference noise from the digital supply. The VBAT pin powers the RTC domain and requires its own decoupling when battery backup is used.

The 121-MAPBGA package uses 0.5 mm ball pitch, which demands 4-layer PCB design with microvia or via-in-pad escape for reliable assembly. Per NXP hardware design guide, route high-speed USB differential pair (D+/D-) with 90 ohm differential impedance and length matching within 150 mil. Place the 33 ohm series termination resistors within 4 mm of the USB connector pins.

Do not skip the 1.5 kohm pull-up resistor on the USB D+ line, or the host will not detect the device at full-speed. Ensure the NMI pin has a defined state at reset - leaving it floating may cause unintended interrupts. The MAPBGA package is MSL3, so assembly must occur within 168 hours of opening the dry-pack bag, or rebaking is required per JEDEC J-STD-033.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per NXP product page. Not AEC-Q100 qualified - this part targets industrial and consumer applications, not automotive. MAPBGA package is MSL3 per JEDEC J-STD-033.

Data verified on: 2026-10-06 — data verified and curated by XAIPART's component engineering team

Related Searches

MK22DX256VMC5 MK22DX256VMC5 datasheet NXP Kinetis K22 50MHz Cortex-M4 121-MAPBGA microcontroller USB Cortex-M4 MCU 256KB Flash USB MK22DX256VMC5 USB HID application MK22DX256VMC5 vs MK22DX256VMC7 MK22DX256VMC5 drop-in replacement MK22DX256VMC5 buy price stock K22 121-MAPBGA pinout MK22DX256VMC5 lead time distributor NXP low-power USB microcontroller

Related Components & Terms

NXP Semiconductors MK22DX256VMC5 MK22DX256VMC7 MK22DX256VMC5R MK22DX128VMC5 MK22DN512VMC5 MK22FX512VMC5 ARM Cortex-M4 FPU Kinetis K22 121-MAPBGA USB 2.0 Full-Speed RoHS JEDEC J-STD-033 MAPBGA package family SAR ADC RTC MCUXpresso IDE
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