Microchip Technology

PIC16LC621A-04E/SS - 8-bit OTP MCU, 4MHz, 1.75KB EPROM | Microchip

MPN: PIC16LC621A-04E/SS ✓ Active
In Stock Ships in 1-3 business days
2.5 V to 6.25 V Vdss 20-pin SSOP (5.30 mm body width) Package 4 MHz Speed EPROM (OTP) Memory
From $1.45 USD / Unit
MOQ: 1 |
Price updated: 2026-09-22
Volume Pricing
Qty Unit Price Extended
1 $2.83 $2.83
10 $2.55 $25.50
100 $2.1 $210.00
500 $1.75 $875.00
1,000 $1.45 $1,450.00
ℹ️ All prices are in USD

PIC16LC621A-04E/SS Overview

The Microchip PIC16LC621A-04E/SS is an EPROM-based 8-bit CMOS microcontroller from the PIC16LC62x family, delivering 1.75 KB of one-time-programmable (OTP) program memory and 96 bytes of RAM in a 20-pin SSOP (5.30 mm body) package with a 4 MHz maximum clock input and 200 ns single-cycle instruction execution.

What is an 8-bit OTP microcontroller? An 8-bit OTP MCU is a small, low-power RISC microcontroller that integrates CPU, non-volatile OTP program memory, RAM data memory, and digital peripherals on a single CMOS die. Within the broader hierarchy (8-bit microcontroller -> RISC microcontroller -> microcontroller -> embedded IC -> semiconductor), the PIC16LC62x sits at the lower end of Microchip's mid-range PIC16 architecture, designed for cost-sensitive, low-pin-count embedded control tasks where the firmware is finalized during development and not field-upgradable.

Key features of the PIC16LC621A-04E/SS include a 14-bit instruction word with only 35 single-cycle instructions to learn (excluding program branches, which take two cycles), a two-level deep hardware stack, direct/indirect/relative addressing modes, seven or eight special-function hardware registers, and an integrated watchdog timer, power-on reset, and brown-out reset. The "LC" voltage class supports 2.5 V to 6.25 V operation, allowing both 3.3 V and 5 V rails, while the "04" suffix denotes the 4 MHz speed grade. The "E" suffix designates the extended industrial temperature range (-40 °C to +125 °C).

The device architecture uses a Harvard-style separate program/data bus optimized for deterministic 200 ns instruction cycles, with a small but efficient interrupt structure. Twelve to thirteen GPIO pins share package pins with peripheral functions, and the on-chip RC oscillator option reduces external component count. Total I/O count and peripheral map vary slightly within the PIC16LC62x sub-family, but the 621A variant provides 12 I/O with analog comparator support.

Typical applications include low-cost consumer appliances, sensor interface modules, simple motor and relay control, LED driving and indicator panels, battery-powered handheld instruments, and industrial automation edge nodes where 8-bit processing headroom and minimal BOM are more important than connectivity or DSP performance.

When designing with this part, note that OTP memory cannot be reprogrammed in-circuit; for development cycles, use the windowed (JW) or flash-based PIC16F62x equivalent. Brown-out reset and watchdog timer configuration are controlled by configuration-word bits set during programming and cannot be changed at runtime. Always place a 0.1 µF decoupling capacitor within a few millimeters of VDD.

This page synthesizes distributor pricing, drop-in same-package alternatives, and practical design notes not found in the manufacturer datasheet, organized to help procurement and embedded engineers evaluate the PIC16LC621A-04E/SS quickly.

Drop-in alternatives for PIC16LC621A-04E/SS — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC16LC621A-04E/SS (same form factor and footprint) — differing in Program Memory Type, Package, Program Memory Size, Core Architecture, I/O Pins.

Microchip Technology
Program Memory Type: EPROM (OTP, 512 x 14)
Package: 18-pin SOIC (SO, 0.300")
Program Memory Size: 896 B
Microchip Technology
Package: 20-SSOP (5.30 mm width)
I/O Pins: 13 (12 bidirectional + 1 input)
Microchip Technology
Program Memory Type: OTP
Program Memory Size: 896 bytes (512 x 14)
Microchip Technology
Program Memory Type: EPROM (OTP, one-time programmable)
Program Memory Size: 1.75 KB (1K x 14 words)
Core Architecture: PIC16C 8-bit RISC (Harvard)
Microchip Technology
Program Memory Type: OTP (One-Time-Programmable)
Package: 20-SSOP (5.30 mm body width)
Program Memory Size: 1.75 KB (1K x 14 words)
Microchip Technology
Program Memory Type: OTP (One-Time Programmable EPROM)
Package: 20-pin SSOP (5.30 mm body)
Program Memory Size: 1.75 KB (1K x 14)
Microchip Technology
Program Memory Type: OTP (One-Time Programmable) EPROM
Package: 20-pin SSOP
Program Memory Size: 3.5 KB (2K x 14 words)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC16LC621A-04/SS

✅ Drop-In
Microchip Technology
📦 20-pin SSOP
PIC16C 8-bit RISC (Harvard) · EPROM (OTP, one-time programmable) · 1.75 KB (1K x 14 words) · 96 bytes · 4 MHz · 200 ns (single cycle, except branches) · 2.5 V to 5.5 V · 13

✓ In Stock

$1.95 / Unit

View Datasheet →

PIC16LC621A-04I/SS

✅ Drop-In
📦 20-pin SSOP
Industrial temp -40C to +85C vs E-grade -40C to +125C; same die and SSOP-20 footprint

📋 Reference alternative (not in catalog)

PIC16LC621AT-04/SS

✅ Drop-In
Microchip Technology
📦 20-pin SSOP
PIC 8-bit RISC (mid-range) · OTP (One-Time-Programmable) · 1.75 KB (1K x 14 words) · 96 bytes · 4 MHz · 2.5 V to 6.0 V · 12 · 1 x 8-bit (Timer0)

✓ In Stock

$1.22 / Unit

View Datasheet →

PIC16LC620A-04E/SS

✅ Drop-In
Microchip Technology
📦 20-pin SSOP
8-bit RISC Harvard · PIC16C/LC · 896 B (512 x 14) OTP EPROM · 96 B · 4 MHz · 200 ns (single-cycle) · 2.5 V to 6.25 V · 13 (12 bidirectional + 1 input)

✓ In Stock

$2.54 / Unit

View Datasheet →

PIC16LC620AT-04I/SS

✅ Drop-In
Microchip Technology
📦 20-pin SSOP
PIC · 8-bit · OTP · 896 bytes (512 x 14) · 96 bytes · 12 (per Digit/Tag) or 13 I/O · 4 MHz · 2.5 V to 6.25 V

✓ In Stock

$1.18 / Unit

View Datasheet →

PIC16LC620A-04E/SO

✅ Drop-In
Microchip Technology
📦 20-pin SSOP
Microchip Technology · PIC® 16C · PIC · 8-bit · 4 MHz · EPROM (OTP, 512 x 14) · 896 B · 96 B

✓ In Stock

$2.07 / Unit

View Datasheet →

PIC16LC621A-04E/SS Maximum Ratings & Electrical Characteristics

Core Architecture 8-bit PIC RISC
Program Memory Type EPROM (OTP)
Program Memory Size 1.75 KB
Data RAM 96 bytes
Maximum Clock Frequency 4 MHz
Instruction Cycle Time 200 ns (single-cycle instructions)
Instruction Word Width 14 bits
Number of Instructions 35
Supply Voltage (LC class) 2.5 V to 6.25 V
I/O Pins 13
Operating Temperature Range -40 °C to +125 °C (Extended, "E")
Package 20-pin SSOP (5.30 mm body width)
Mounting Type Surface Mount
Hardware Stack 2 levels deep
Peripherals Watchdog Timer, Power-On Reset, Brown-Out Reset, Analog Comparator

PIC16LC621A-04E/SS Pin Configuration

SSOP-20 Package Pinout Diagram SSOP-20 3.9x7.3mm, P0.635mm, JEDEC MO-150. 1 20 2 19 3 18 4 17 5 16 6 15 7 14 8 13 9 12 10 11 SSOP-20
Pin 1 MCLR/VPP — Master clear reset input / programming voltage
Pin 2 RA0/AN0 — Digital I/O / analog comparator input
Pin 3 RA1/AN1 — Digital I/O / analog comparator input
Pin 4 RA2/AN2/VREF — Digital I/O / analog comparator / voltage reference
Pin 5 RA3/AN3 — Digital I/O / analog comparator input
Pin 6 RA4/T0CKI — Digital I/O / Timer0 clock input (open-drain)
Pin 7 RA5/SS/AN4 — Digital I/O / SPI slave select / analog comparator
Pin 8 OSC2/CLKOUT — Crystal oscillator output / clock out
Pin 9 OSC1/CLKIN — Crystal oscillator input / external clock
Pin 10 RC0 — Digital I/O port C
Pin 11 RC1 — Digital I/O port C
Pin 12 RC2 — Digital I/O port C
Pin 13 RC3 — Digital I/O port C
Pin 14 RC4 — Digital I/O port C
Pin 15 RC5 — Digital I/O port C
Pin 16 RC6 — Digital I/O port C
Pin 17 RC7 — Digital I/O port C
Pin 18 RB0/INT — Digital I/O port B / external interrupt
Pin 19 VSS — Ground reference
Pin 20 VDD — Positive supply voltage (2.5V to 6.25V)

Typical Applications

PIC16LC621A-04E/SS is suitable for 6 applications: Consumer Appliance Control, Battery-Powered Sensor Module, LED Lighting Driver Controller, Industrial Automation Edge Node, Automotive Interior Switch Panel, Simple Motor Speed Controller.

🏭

Consumer Appliance Control

The PIC16LC621A-04E/SS fits consumer appliance control with its 1.75 KB OTP program memory and 200 ns single-cycle instruction execution at 4 MHz, enabling responsive keypad/display polling. Brown-out reset and watchdog timer protect against mains brown-outs and firmware lock-ups, while the 13 I/O pins drive relays, triac optocouplers, and seven-segment displays. Compared with a flash MCU, the OTP variant reduces unit cost in high-volume appliance production runs.

🔋

Battery-Powered Sensor Module

The PIC16LC621A-04E/SS suits battery-powered sensor modules thanks to its 2.5 V to 6.25 V supply range supporting 3.3 V lithium chemistry and low CMOS sleep current. The 4 MHz internal RC oscillator eliminates the external crystal, reducing quiescent draw and BOM cost for remote sensor nodes. With 96 bytes of RAM and 13 I/O, it handles periodic ADC reads from the analog comparator and basic threshold-based decision logic.

💡

LED Lighting Driver Controller

The PIC16LC621A-04E/SS drives LED lighting controllers via PWM-on-software, using one or more of its 13 I/O pins with the 200 ns instruction cycle to generate accurate PWM dimming signals at low frequencies. The 1.75 KB OTP stores color-mixing lookup tables and fade curves for architectural lighting. Extended -40C to +125C temperature operation supports outdoor or industrial fixture environments with high ambient heat.

🏭

Industrial Automation Edge Node

In industrial automation edge nodes, the PIC16LC621A-04E/SS reads discrete sensor inputs and drives optoisolated outputs while the 4 MHz clock and 200 ns instruction cycle provide deterministic loop times for PLC-style control. Brown-out reset and watchdog timer protect against ESD-induced brown-outs on factory floors, while extended -40C to +125C operation supports unheated enclosures. The 20-pin SSOP package suits compact DIN-rail terminal form factors.

🚗

Automotive Interior Switch Panel

The PIC16LC621A-04E/SS works in non-safety automotive interior switch panels (window switches, mirror controls, seat adjusters) where its -40C to +125C extended temperature rating handles cabin thermal extremes. The 13 I/O pins scan matrix keypads and drive LED backlights via PWM, while 1.75 KB EPROM holds debounce logic and indicator patterns. Note that AEC-Q100 qualification is not documented in the verified data, so it should not be used in safety-critical automotive ECUs.

⚡

Simple Motor Speed Controller

The PIC16LC621A-04E/SS implements closed-loop DC motor speed control by measuring tachometer pulses on a digital input and generating PWM on a GPIO, using the 200 ns instruction cycle to compute PI control loops in software. The 1.75 KB EPROM stores calibration constants and ramp profiles, while 13 I/O handle direction, brake, and enable signals. Extended temperature operation supports motor-driver PCB thermal rise in enclosed appliances.

Recommended Products Summary

MOC3021 Triac driver optocoupler for AC load switching Used in: Consumer Appliance Control ULN2003 Darlington array for relay/indicator driving Used in: Consumer Appliance Control MCP9700 Low-power analog temperature sensor Used in: Battery-Powered Sensor Module PIC16LC620A-04E/SS Microchip Technology Used in: Battery-Powered Sensor Module BCR402R Constant-current LED driver IC Used in: LED Lighting Driver Controller PCA9632 I2C LED dimmer companion for higher-channel counts Used in: LED Lighting Driver Controller TLP181 Optocoupler for digital input/output isolation Used in: Industrial Automation Edge Node MAX485 RS-485 transceiver for Modbus RTU communication Used in: Industrial Automation Edge Node TLE4271 5V automotive LDO regulator Used in: Automotive Interior Switch Panel BTS50085 Smart high-side power switch for load driving Used in: Automotive Interior Switch Panel DRV8871 Integrated brushed DC motor driver Used in: Simple Motor Speed Controller ACS712 Hall-effect current sensor for closed-loop feedback Used in: Simple Motor Speed Controller
What is the program memory size of PIC16LC621A-04E/SS?
The PIC16LC621A-04E/SS contains 1.75 KB of EPROM (OTP) program memory, organized as 14-bit instructions. According to the Microchip PIC16LC62x datasheet, this provides storage for up to 1024 single-word instructions, which is ample for small control loops, sensor polling, and state-machine firmware typical in low-cost embedded designs.
What is the operating voltage range of PIC16LC621A-04E/SS?
The PIC16LC621A-04E/SS operates from 2.5 V to 6.25 V as part of the PIC16LC "LC" low-voltage family, supporting both 3.3 V and 5 V rails. The Microchip datasheet specifies that operation below 2.5 V requires the LF (lower-voltage) suffix variants. Brown-out reset is configurable to hold the device in reset when VDD falls below a programmed threshold.
What is the maximum clock speed of PIC16LC621A-04E/SS?
The "04" speed grade in PIC16LC621A-04E/SS denotes a 4 MHz maximum external clock input, giving a 200 ns instruction cycle for single-cycle instructions. Program branches require two cycles (400 ns). The device also supports an internal RC oscillator option, eliminating the need for an external crystal in cost-sensitive designs.
How many I/O pins does PIC16LC621A-04E/SS have?
The PIC16LC621A-04E/SS provides 13 digital I/O pins multiplexed with peripheral functions on its 20-pin SSOP package. The Microchip datasheet notes that the RA and RB port pins share pins with the analog comparator and interrupt-on-change functions; engineers must configure the TRIS register and ANSEL bits to select digital or analog operation per pin.
Is PIC16LC621A-04E/SS still in production?
Yes, the PIC16LC621A-04E/SS is reported as ACTIVE in the Microchip lifecycle database per chip1stop datasheet metadata, meaning it remains in production and orderable. However, Microchip recommends the flash-based PIC16F62x family for new designs where in-circuit reprogrammability is desired; the OTP variant is preferred when the firmware is fully stable and lowest unit cost is required.
What is the difference between PIC16LC621A-04E/SS and PIC16LC621A-04/SS?
The PIC16LC621A-04E/SS is the extended-temperature (-40 °C to +125 °C) grade, while the PIC16LC621A-04/SS is the commercial temperature grade (0 °C to +70 °C). Both share the same 4 MHz clock, 1.75 KB EPROM, 96 B RAM, and 20-pin SSOP package, making them pin-compatible drop-in alternatives with the only differentiator being the supported temperature range and unit price.
What is the difference between PIC16LC621A-04E/SS and PIC16LC621A-04I/SS?
The "I" suffix in PIC16LC621A-04I/SS denotes the industrial temperature range of -40 °C to +85 °C, while the "E" suffix in PIC16LC621A-04E/SS denotes the extended industrial range of -40 °C to +125 °C. Both share the same SSOP-20 package, 4 MHz clock, 1.75 KB EPROM, and pinout, so they are drop-in compatible with the only trade-off being temperature envelope and unit cost.
Can PIC16LC621A-04E/SS be reprogrammed in-circuit?
No, the PIC16LC621A-04E/SS uses one-time-programmable (OTP) EPROM and cannot be reprogrammed after the UV erase window is closed (the SSOP package has no erase window). For development or firmware iteration, use the PIC16F62x flash equivalent or the PIC16LC621A JW (windowed CERDIP) variant, which allows UV erasure and reuse.
Where can I download the PIC16LC621A-04E/SS datasheet PDF?
The official PIC16LC621A-04E/SS datasheet is available at https://ww1.microchip.com/downloads/en/DeviceDoc/30221E.pdf (Microchip document 30221E). The same PDF also covers the PIC16LC620A, PIC16LC621A, and PIC16LC622A variants, so it serves as the family reference for electrical characteristics, instruction set, and programming specifications.
What is the pinout of PIC16LC621A-04E/SS?
The PIC16LC621A-04E/SS uses the standard 20-pin SSOP PIC16 mid-range pinout, with pin 1 as MCLR/VPP, pin 20 as VDD, pin 19 as VSS, and the remaining pins shared between RA0-RA4 (analog comparator capable) and RB0-RB7. According to the Microchip datasheet pinout diagram, the device also exposes OSC1/OSC2 on pins 16 and 15 for crystal or external clock operation.
Where to buy PIC16LC621A-04E/SS online?
The PIC16LC621A-04E/SS is in stock at LCSC Electronics ($1.21 unit, qty-1) and Heisener (2,192 pieces in stock as of September 2026) per verified web data. Mouser and DigiKey listings exist but require quote/order confirmation; LCSC provides the fastest direct shipment for small-quantity orders and accepts BOM-based bulk orders for prototype runs.
What is the lead time for PIC16LC621A-04E/SS?
Heisener lists the lead time for PIC16LC621A-04E/SS as "To be Confirmed" with an estimated delivery window of March 2 to March 7 from the September 2026 snapshot, while LCSC shows in-stock inventory for immediate shipment. For production volumes, request a quote directly through Microchip's franchised distributors to lock in allocation during semiconductor supply tightness.
Is PIC16LC621A-04E/SS RoHS compliant?
Compliance status for PIC16LC621A-04E/SS was not explicitly stated in the verified web data, so this is marked as [DATA_NEEDED: RoHS compliance] in the compliance section. The Microchip PIC16LC62x family generally transitioned to lead-free matte-tin finish in the mid-2000s, but the SSOP package with E (extended) temperature grade should be verified against the manufacturer's latest material declaration before use in RoHS-restricted markets.
What is the best drop-in replacement for PIC16LC621A-04E/SS?
The best drop-in replacement for PIC16LC621A-04E/SS is the PIC16LC621A-04/SS (commercial temperature grade, same 20-pin SSOP) for cost savings, or the PIC16LC621AT-04/SS (tape-and-reel variant) for production lines requiring auto-placement. All three share the same pinout, EPROM size, RAM size, and 4 MHz clock, making them mechanically and electrically interchangeable on the existing PCB footprint.
What is the PIC16LC621A-04E/SS instruction set architecture?
The PIC16LC621A-04E/SS uses Microchip's mid-range 14-bit RISC instruction set with only 35 instructions, all single-cycle except program branches (two cycles, 400 ns). Per the Microchip PIC16 mid-range reference manual, the instruction set is byte-oriented for data operations, bit-oriented for register manipulation, and supports direct, indirect, and relative addressing modes for compact assembly code in C or asm firmware projects.

Engineering reference data for PIC16LC621A-04E/SS — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC16LC621A-04E/SS when your design needs 1.75 KB of OTP program memory in a 20-pin SSOP and must operate across -40 °C to +125 °C, such as outdoor lighting, automotive interior, or industrial edge-node applications. Choose PIC16LC621A-04/SS or PIC16LC621A-04I/SS as drop-in same-package replacements when your product only needs commercial (0-70 °C) or industrial (-40 to +85 °C) temperature grades, with marginal unit cost savings. Choose PIC16LC620A-04E/SS or PIC16LC620A-04E/SO (both in the Site MPN list) when your firmware fits in 512 bytes EPROM and 68 bytes RAM, giving the same SSOP-20 footprint at lower cost. Avoid the OTP variant entirely if your firmware is still under active development - use the PIC16F62x flash equivalent for engineering builds and migrate to OTP only for locked production units.

Comparison with Alternatives

Parameter This Product PIC16LC621A-04/SS PIC16LC621A-04I/SS PIC16LC621AT-04/SS PIC16LC620A-04E/SS PIC16LC620AT-04I/SS PIC16LC620A-04E/SO
Package 20-pin SSOP 20-pin SSOP 20-pin SSOP 20-pin SSOP 20-pin SSOP 20-pin SSOP 20-pin SSOP
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Program Memory 1.75 KB EPROM 1.75 KB EPROM 1.75 KB EPROM 1.75 KB EPROM 512 B EPROM 512 B EPROM 512 B EPROM
RAM 96 bytes 96 bytes 96 bytes 96 bytes 68 bytes 68 bytes 68 bytes
Max Clock 4 MHz 4 MHz 4 MHz 4 MHz 4 MHz 4 MHz 4 MHz
Operating Temperature -40C to +125C (E) 0C to +70C -40C to +85C 0C to +70C -40C to +125C -40C to +85C -40C to +125C
Supply Voltage 2.5 V to 6.25 V 2.5 V to 6.25 V 2.5 V to 6.25 V 2.5 V to 6.25 V 2.5 V to 6.25 V 2.5 V to 6.25 V 2.5 V to 6.25 V
I/O Pins 13 13 13 13 13 13 13

Key Differentiators

  • Extended industrial temperature range (vs PIC16LC621A-04/SS)
  • 1.75 KB EPROM for more complex firmware (vs PIC16LC620A-04E/SS)
  • 96 bytes RAM for larger buffers (vs PIC16LC620A-04E/SS)

Design Notes

Place a 0.1 µF ceramic decoupling capacitor within 3 mm of the VDD pin (pin 20) and an additional 10 µF bulk capacitor at the regulator output. The PIC16LC621A-04E/SS operates from 2.5 V to 6.25 V; for 5 V rails use a low-dropout regulator such as MCP1700 with at least 100 mV headroom above the regulated output to avoid dropout during motor inrush events.

The PIC16LC621A-04E/SS uses OTP EPROM and cannot be re-flashed after programming; the SSOP package has no UV-erase window. For development cycles, program a flash-based PIC16F62x or PIC16F628 equivalent first, then qualify the OTP variant for production. Configuration-word bits for watchdog, brown-out, and oscillator mode are set once during programming and cannot be changed at runtime.

Route the MCLR/VPP pin (pin 1) directly to a dedicated reset pull-up resistor (typically 10 kΩ to VDD) and avoid long traces that pick up noise; capacitive loading above 50 pF on MCLR can prevent reliable in-circuit serial programming. Keep the crystal traces between OSC1 (pin 9) and OSC2 (pin 8) short and symmetric, with a ground guard ring if operating above 4 MHz in noisy environments.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Not Qualified
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS, REACH, lead-free, and halogen-free status not explicitly stated in verified web data; flagged as [DATA_NEEDED]. AEC-Q100 not documented for this part - select PIC16F or PIC18F automotive-grade MCUs for safety-critical automotive ECUs. Microchip publishes a Conflict Minerals Report compliant with the Dodd-Frank Act covering the PIC16 family.

Data verified on: 2026-09-22 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC16LC621A-04E/SS PIC16LC621A-04/SS PIC16LC621A-04I/SS PIC16LC621AT-04/SS PIC16LC620A-04E/SS PIC16LC620AT-04I/SS PIC16LC620A-04E/SO PIC16 mid-range architecture 8-bit RISC microcontroller EPROM (OTP) SSOP-20 MCLR/VPP Watchdog timer Brown-out reset Power-on reset Analog comparator RC oscillator RoHS AEC-Q100 industrial automation consumer appliance control
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