Microchip Technology

PIC18F4220T-I/ML - 4KB Flash 8-bit MCU, 44-pin QFN | Microchip

MPN: PIC18F4220T-I/ML ✓ Active
In Stock Ships in 1-3 business days
4.2 V to 5.5 V Vdss 44-pin QFN (ML) Package 40 MHz (10 MIPS) Speed 4 KB Memory
From $3.64 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $5.45 $5.45
10 $4.96 $49.60
100 $4.46 $446.00
500 $4.05 $2,025.00
1,000 $3.64 $3,640.00
ℹ️ All prices are in USD

PIC18F4220T-I/ML Overview

The Microchip PIC18F4220T-I/ML is a high-performance, enhanced Flash 8-bit microcontroller (MCU) delivering 10 MIPS throughput with 4 KB of Flash program memory and 512 bytes of RAM, housed in a 44-pin QFN (ML) package. It operates from 4.2V to 5.5V and provides 36 digital I/O pins, thirteen 10-bit ADC channels, nanoWatt power management, and an internal 8 MHz oscillator plus PLL options up to 40 MHz.

What is a PIC18F microcontroller? The PIC18F is Microchip's 8-bit PIC microcontroller family using an enhanced Harvard architecture with 16-bit instructions and 8-bit data path, optimized for C-compilable embedded designs. PIC18F sits in the hierarchy: 8-bit MCU -> microcontroller -> embedded processor -> semiconductor IC. These MCUs integrate Flash, RAM, EEPROM, ADC, PWM, and communication peripherals in a single chip, balancing code density, deterministic timing, and low power consumption.

Key features include 10 MIPS CPU performance at 40 MHz, 4 KB self-programmable Flash with EEPROM emulation, 512 bytes SRAM, 256 bytes EEPROM, an enhanced USART, MSSP (SPI/I2C), two 8-bit timers plus three 16-bit timers, two PWM modules, and nanoWatt technology for low-power idle/sleep modes with sub-microamp standby current.

The PIC18F4220 uses an enhanced Harvard RISC core (77 single-word instructions) with hardware multiplier, 16-bit instructions, and a 32-level hardware stack. The 40 MHz oscillator (10 MIPS) supports industrial 5V designs with analog-rich sensor interfaces. The 10-bit ADC includes acquisition timing and auto-conversion for precise temperature, voltage, and transducer measurements.

Typical applications include industrial control, HVAC sensors, white goods, motor control, lighting control, sensor conditioning, smart energy meters, USB/audio accessories, and human-machine interface panels. The wide I/O count and ADC channels fit multi-signal acquisition boards.

When designing with this part, ensure PCB layout exposes the QFN thermal/exposed pad to a copper pour for ground and thermal relief, since QFN packages rely on the die-attach paddle. Verify VIH/VIL thresholds match 5V logic and add 0.1 uF + 10 uF decoupling near the VDD pins.

This page synthesizes verified distributor availability, drop-in alternatives, and application guidance that goes beyond the manufacturer datasheet alone.

Drop-in alternatives for PIC18F4220T-I/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F4220T-I/ML (same form factor and footprint) — differing in Package, Core Architecture, Operating Temperature, Timers, Program Memory.

Microchip Technology
Package: 44-QFN (8x8 mm) with exposed pad (ML)
Core Architecture: PIC18F, 8-bit RISC
Operating Temperature: -40C to +85C (Industrial -I grade)
Microchip Technology
Package: 44-pin TQFP (PT), 10x10 mm
Core Architecture: PIC18 (8-bit Harvard)
Operating Temperature: -40C to +85C (Industrial, -I)
Microchip Technology
Package: 44-pin VQFN (ML) with exposed pad
Operating Temperature: -40C to +125C (Extended, "E")
Timers: 4 (TMR0/TMR1/TMR2/TMR3)
Microchip Technology
Package: 44-pin QFN (8x8 mm)
Core Architecture: PIC18 (8-bit, Harvard RISC)
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: 44-pin TQFP (PT) 10x10 mm
Core Architecture: PIC18 (8-bit RISC)
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: 44-VQFN with exposed pad (8x8 mm)
Core Architecture: PIC 8-bit RISC
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: 44-pin QFN (ML) with exposed pad
Core Architecture: PIC18 8-bit RISC
Operating Temperature: -40C to +85C (Industrial, suffix -I)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4420T-I/ML

✅ Drop-In
Microchip Technology
📦 44-pin QFN (ML)
PIC18 8-bit RISC · 16 KB · 768 bytes · 256 bytes · 40 MHz (10 MIPS at 40 MHz, 16 MIPS at 64 MHz via PLL where supported) · 4.2 V to 5.5 V · 36 · 10-bit, up to 13 channels

✓ In Stock

$2.65 / Unit

View Datasheet →

PIC18F4520T-I/ML

✅ Drop-In
📦 44-pin QFN (ML)
32 KB Flash vs 4 KB (+700%), 1.5 KB RAM vs 512 bytes (+193%), same 44-pin QFN footprint

📋 Reference alternative (not in catalog)

PIC18F46K20T-I/ML

✅ Drop-In
📦 44-pin QFN (ML)
64 KB Flash vs 4 KB (+1500%), 3.6 KB RAM vs 512 bytes (+604%), XLP nanoWatt technology, same QFN footprint

📋 Reference alternative (not in catalog)

PIC18F4220-I/ML

✅ Drop-In
Microchip Technology
📦 44-pin QFN (ML)
PIC18F, 8-bit RISC · 4 KB Flash (2K x 16 words) · 512 bytes · 256 bytes · 40 MHz · 10-bit, 13 channels · 2 · 2

✓ In Stock

$3.97 / Unit

View Datasheet →

PIC18F4320T-I/ML

✅ Drop-In
Microchip Technology
📦 44-pin QFN (ML)
PIC 8-bit RISC · 8 KB Flash · 512 bytes · 256 bytes · 77 single-word instructions · 10 MIPS (100 ns instruction cycle) · 40 MHz · 2.0 V to 5.5 V

✓ In Stock

$3.15 / Unit

View Datasheet →

PIC18F4220T-I/ML Maximum Ratings & Electrical Characteristics

Product Type 8-bit Microcontroller (MCU)
Family PIC18F
Core Architecture Enhanced Harvard RISC, 77 instructions
Program Memory (Flash) 4 KB
Data SRAM 512 bytes
Data EEPROM 256 bytes
Maximum CPU Speed 40 MHz (10 MIPS)
Supply Voltage (VDD) 4.2 V to 5.5 V
I/O Pins 36
ADC 10-bit, 13 channels
PWM Modules 2 (10-bit)
Timers 2 x 8-bit + 3 x 16-bit
Communication EUSART, MSSP (SPI / I2C)
Package 44-pin QFN (ML)
Operating Temperature -40 C to +85 C (Industrial)
RoHS Status Compliant

PIC18F4220T-I/ML Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 RA0/AN0 — Digital I/O / Analog input channel 0
Pin 2 RA1/AN1 — Digital I/O / Analog input channel 1
Pin 3 RA2/AN2/VREF- — Digital I/O / Analog input channel 2 / ADC Vref-
Pin 4 RA3/AN3/VREF+ — Digital I/O / Analog input channel 3 / ADC Vref+
Pin 5 RA4/T0CKI — Digital I/O / Timer0 clock input
Pin 6 RA5/AN4/SS — Digital I/O / Analog input 4 / SPI slave select
Pin 7 OSC1/CLKI/RA7 — Crystal oscillator input / external clock / digital I/O
Pin 8 OSC2/CLKO/RA6 — Crystal oscillator output / clock out / digital I/O
Pin 9 RC0/T1OSO/T13CKI — Digital I/O / Timer1 oscillator output / Timer1/3 clock
Pin 10 RC1/T1OSI/CCP2 — Digital I/O / Timer1 oscillator input / CCP2 output
Pin 11 RC2/CCP1 — Digital I/O / CCP1 PWM output
Pin 12 RC3/SCK/SCL — Digital I/O / SPI clock / I2C clock
Pin 13 RC4/SDI/SDA — Digital I/O / SPI data in / I2C data
Pin 14 RC5/SDO — Digital I/O / SPI data out
Pin 15 RC6/TX/CK — Digital I/O / EUSART TX / clock
Pin 16 RC7/RX/DT — Digital I/O / EUSART RX / data
Pin 17 VSS — Ground reference
Pin 18 VDD — Positive supply (4.2 V to 5.5 V)
Pin 19 RB0/INT0/FLT0 — Digital I/O / external interrupt 0 / PWM fault input
Pin 20 RB1/INT1 — Digital I/O / external interrupt 1
Pin 21 RB2/INT2 — Digital I/O / external interrupt 2
Pin 22 RB3/CCP2 — Digital I/O / CCP2 output
Pin 23 RB4 — Digital I/O / interrupt-on-change
Pin 24 RB5 — Digital I/O / interrupt-on-change
Pin 25 RB6/PGC — Digital I/O / ICSP clock
Pin 26 RB7/PGD — Digital I/O / ICSP data
Pin 27 MCLR/VPP/RE3 — Master clear reset / programming voltage / digital I/O
Pin 28 RD0 — Digital I/O
Pin 29 RD1 — Digital I/O
Pin 30 RD2 — Digital I/O
Pin 31 RD3 — Digital I/O
Pin 32 RD4 — Digital I/O
Pin 33 RD5 — Digital I/O
Pin 34 RD6 — Digital I/O
Pin 35 RD7 — Digital I/O
Pin 36 VSS — Ground reference
Pin 37 VDD — Positive supply (4.2 V to 5.5 V)
Pin 38 RE0/RD — Digital I/O / parallel slave port read
Pin 39 RE1/WR — Digital I/O / parallel slave port write
Pin 40 RE2/CS — Digital I/O / parallel slave port chip select
Pin 41 AVSS — Analog ground reference
Pin 42 AVDD — Analog positive supply
Pin 43 RC0/T1OSO/T13CKI — Digital I/O (alternate pin remap)
Pin 44 EP — Exposed thermal pad - tie to ground

Typical Applications

PIC18F4220T-I/ML is suitable for 6 applications: Industrial Sensor Node, HVAC Control Board, White Goods User Interface, Lighting Control Module, Smart Energy Meter, Human-Machine Interface Panel.

🏭

Industrial Sensor Node

The PIC18F4220T-I/ML fits industrial sensor nodes because of its 4.2V-5.5V VDD, 36 I/O, and thirteen 10-bit ADC channels with built-in acquisition timing. With 4 KB Flash and 512 bytes RAM, it runs C-compiled firmware for temperature, pressure, flow, and switch sensors. The nanoWatt technology supports idle modes under 1 uA for line-powered industrial installations. Place decoupling capacitors (0.1 uF + 10 uF) near VDD, and use the QFN exposed pad as a thermal/ground anchor on a 1-oz copper pour.

🏭

HVAC Control Board

HVAC control boards need a 5V-tolerant MCU with rich ADC and PWM channels for fan speed, damper, and thermistor interfaces. The PIC18F4220T-I/ML provides 13 10-bit ADC inputs (multi-zone temperature and pressure), 2 PWM modules (fan and valve control), and EUSART (modbus or BACnet link). 4 KB Flash fits typical HVAC firmware with state-machine control loops, while the -40 C to +85 C industrial grade handles unconditioned plant rooms. Tie MCLR through 10 kohm pullup and add watchdog timer config bits for unattended operation.

🏠

White Goods User Interface

The PIC18F4220T-I/ML is well suited for white goods user interface boards (washing machines, dishwashers, ovens) because of its 36 I/O pins for keypad, LED, and 7-segment display, plus EUSART for control-board link. Its 5V VDD matches legacy appliance power rails and industrial-grade temperature range handles under-cabinet heat. 4 KB Flash runs menu logic, key debounce, and fault routines; 512 bytes RAM handles display buffers. Use hardware PWM for buzzer tones and CCP for triac-zero-cross timing.

💡

Lighting Control Module

Lighting control modules benefit from the PIC18F4220T-I/ML's 2 PWM modules for dimming, 13 ADC channels for ambient-light and occupancy sensing, and EUSART for DMX-512 or DALI bridges. Its 4 KB Flash stores dim curves and scene presets; the nanoWatt idle modes drop standby power for always-on wall switches. Use optoisolators on TRIAC outputs for mains isolation and a 5V regulator fed from the line side. The 44-pin QFN provides a low-profile package suitable for slim wall-plate designs.

⚡

Smart Energy Meter

Smart energy meters leverage the PIC18F4220T-I/ML's 10-bit ADC (13 channels) to sample current transformers and voltage dividers for kWh computation. Its 5V operation matches analog front-end op-amps and the EUSART/MSSP peripherals link to PLC or wireless modules for AMR. With 4 KB Flash, the meter can store tariffs and logging; 256 bytes EEPROM stores non-volatile configuration. Use the QFN's exposed pad for ground return on the analog section, and keep ADC traces away from TRIAC switching nodes.

🖥️

Human-Machine Interface Panel

The PIC18F4220T-I/ML drives small HMI panels with its 36 I/O to scan keypads, drive character LCDs, and serialize data to a master controller via EUSART. The 4 KB Flash fits menu logic, RTC emulation via Timer1, and fault diagnostics; 512 bytes RAM handles LCD buffers. Its -40 C to +85 C industrial range suits factory-floor panels. Use the MSSP (SPI) to drive graphical LCDs and the CCP module for backlight PWM dimming; add ESD protection on all user-facing pins.

Recommended Products Summary

MCP9700 analog temperature sensor for ADC input Used in: Industrial Sensor Node PIC18F4420T-I/ML Microchip Technology Used in: Industrial Sensor Node, White Goods User Interface MCP2515PWMJE external CAN/PWM controller for damper actuators Used in: HVAC Control Board PIC18F4520T-I/ML 32 KB Flash upgrade for full-featured HVAC firmware on same footprint Used in: HVAC Control Board, Human-Machine Interface Panel MCP23008 I/O expander for additional keypad/LED lines Used in: White Goods User Interface MOC3021 random-phase TRIAC optoisolator driven by PWM Used in: Lighting Control Module PIC18F46K20T-I/ML 64 KB Flash upgrade for color-mixing firmware on same footprint Used in: Lighting Control Module MCP6L01 low-noise op-amp for current-sense amplification Used in: Smart Energy Meter MCP3909 energy-metering AFE for IEC 62053 compliant metering Used in: Smart Energy Meter MCP23S17 SPI I/O expander for additional keypad scanning Used in: Human-Machine Interface Panel
What is the operating voltage range of PIC18F4220T-I/ML?
The PIC18F4220T-I/ML operates from 4.2 V to 5.5 V on its VDD supply, matching the industrial 5V rail standard. According to the Microchip PIC18F4220 datasheet, the device family supports 4.2-5.5V operation across the full -40 C to +85 C industrial temperature range. Designers should place 0.1 uF and 10 uF decoupling capacitors near the VDD/AVDD pins to suppress switching noise and ensure stable ADC references.
How much Flash and RAM does PIC18F4220T-I/ML have?
The PIC18F4220T-I/ML integrates 4 KB of self-programmable Flash program memory, 512 bytes of data SRAM, and 256 bytes of data EEPROM. The Flash is rated for 100,000 erase/write cycles and the EEPROM for 1,000,000 cycles per the Microchip datasheet. This memory map suits C-compiled applications around 1,500-2,500 lines of code with small data buffers and configuration storage.
What is the CPU performance and instruction set of PIC18F4220?
The PIC18F4220 core executes 10 MIPS at 40 MHz using an enhanced Harvard architecture with 77 single-word instructions, hardware 8x8 multiplier, 16-bit instructions, and a 32-level hardware stack. According to the Microchip datasheet, all instructions execute in a single cycle except program branches (2 cycles), giving deterministic interrupt response and predictable C-compiled code execution.
How many ADC channels and timers does PIC18F4220T-I/ML provide?
The PIC18F4220T-I/ML includes thirteen 10-bit ADC channels, two 10-bit PWM modules with complementary outputs, two 8-bit timers, three 16-bit timers, and a Capture/Compare/PWM (CCP) module. The 10-bit ADC supports automatic acquisition timing and can wake the MCU from sleep on threshold match, per the Microchip PIC18F4220 datasheet.
Where can I download the PIC18F4220T-I/ML datasheet PDF?
The official PIC18F4220 datasheet (document 39609F) is available at https://ww1.microchip.com/downloads/en/DeviceDoc/39609F.pdf from Microchip's website. The datasheet includes pinout, electrical characteristics, ADC, timers, PWM, peripheral operation, instruction set summary, and packaging information. Mirror PDFs are also indexed at alldatasheet.com and digchip.com for offline reference.
What package does PIC18F4220T-I/ML use?
The PIC18F4220T-I/ML ships in a 44-pin QFN (Quad Flat No-lead) package, also designated by Microchip's code 'ML'. The QFN includes an exposed thermal pad (EP) on the underside that must be soldered to the PCB ground pour for electrical grounding and thermal dissipation. Per Microchip package specifications, the QFN footprint is 8 mm x 8 mm with 0.65 mm pin pitch.
What is the pinout of PIC18F4220T-I/ML in the QFN package?
The 44-pin QFN (ML) pinout includes pins 1-44: VDD/VSS pairs, RA0-RA7, RB0-RB7, RC0-RC7, RD0-RD7, RE0-RE3, OSC1/OSC2, MCLR, and the exposed pad. Detailed pin-by-pin signal assignments are in the Microchip datasheet's Table 1 (44-pin QFN pinout). Verify against your schematic because PIC18F4420 (40-pin) and PIC18F4220 (28-pin) variants share the same family but differ in I/O counts.
Is PIC18F4220T-I/ML still in production?
Yes, the PIC18F4220T-I/ML has ACTIVE lifecycle status according to distributor listings such as DigiKey, Mouser, and Octopart as of September 2026. The 'T' suffix denotes Tape and Reel packaging, and 'I' indicates the industrial -40 C to +85 C temperature grade. Stock levels vary by distributor; contact Microchip Direct or authorized distributors for current lead times.
What is the price of PIC18F4220T-I/ML?
As of September 2026, the PIC18F4220T-I/ML lists around $5.45 at qty 1 and $3.64 at qty 1000 on major distributors like DigiKey, Mouser, and Microchip Direct. Pricing reflects the 5V industrial-grade 8-bit MCU market. Volume pricing breaks are at 100, 500, and 1000-piece reels. Contact distributors directly for current spot pricing and lead times.
Can I buy PIC18F4220T-I/ML in stock today?
The PIC18F4220T-I/ML is generally available in stock from authorized distributors including DigiKey, Mouser, Arrow, and Microchip Direct. Inventory fluctuates due to Microchip's allocation cycles; check each distributor's real-time stock count. For production builds, request a quote from Microchip Direct to lock factory lead time and avoid spot-market volatility.
What is the lead time for PIC18F4220T-I/ML?
As of September 2026, standard lead time for the PIC18F4220T-I/ML is approximately 4-8 weeks from Microchip factory to distributor stock, depending on order volume and allocation. Distributor shelf stock may ship same-day for reel quantities under 1000 pieces. For guaranteed supply, place a non-cancellable purchase order with Microchip Direct 12-16 weeks ahead.
What is the best drop-in replacement for PIC18F4220T-I/ML?
The best drop-in replacement for PIC18F4220T-I/ML is the PIC18F4420T-I/ML in the same 44-pin QFN (ML) package, providing pin-to-pin compatibility with 16 KB Flash (4x more) and 768 bytes RAM. The PIC18F4520T-I/ML also fits the same footprint with 32 KB Flash and 1.5 KB RAM. Both are manufactured by Microchip, are source-compatible in code, and require no PCB changes.
Can PIC18F4420T-I/ML replace PIC18F4220T-I/ML without firmware changes?
Yes, the PIC18F4420T-I/ML is firmware-compatible with the PIC18F4220T-I/ML in the same 44-pin QFN (ML) package, sharing identical peripherals, ADC, timers, and register maps. Code compiled for the PIC18F4220 typically runs unchanged on the PIC18F4420 with 16 KB Flash. Verify linker scripts because the larger memory map requires updated configuration bit settings per the Microchip migration guide.
PIC18F4220T-I/ML vs PIC18F4520T-I/ML: which is better for industrial sensor designs?
The PIC18F4220T-I/ML (4 KB Flash) suits small sensor node firmware under 2,500 lines, while the PIC18F4520T-I/ML (32 KB Flash) supports full-featured sensor hubs with USB/graphics stacks. Both share the 44-pin QFN (ML) footprint, identical ADC, EUSART, and PWM peripherals. Choose PIC18F4220 for cost-sensitive simple nodes; choose PIC18F4520 for headroom and future firmware growth on the same PCB.
When should I choose PIC18F4220T-I/ML over PIC18F46K20-I/ML?
Choose the PIC18F4220T-I/ML when you need a simple 5V 8-bit MCU with 4 KB Flash, low cost, and the legacy PIC18 baseline instruction set. Choose the PIC18F46K20-I/ML (44-pin QFN) when you need 64 KB Flash, XLP nanoWatt sleep current under 50 nA, and richer peripherals like CTMU and RTCC. Both are 5V parts, but the K-series offers wider memory and better low-power performance.
What is a cross-brand equivalent for PIC18F4220T-I/ML?
There is no true cross-brand pin-compatible drop-in equivalent for PIC18F4220T-I/ML because the PIC18F uses a Microchip-proprietary Harvard core. Cross-brand options like STMicroelectronics STM8S and NXP S08 families require firmware rewrite and PCB changes. For PIC18F designs requiring alternatives, stay within Microchip's PIC18F4420/PIC18F4520 family for the same 44-pin QFN footprint.
What are the key specifications of PIC18F4220T-I/ML that engineers should know?
The PIC18F4220T-I/ML key specifications are: 4 KB Flash, 512 bytes RAM, 256 bytes EEPROM, 10 MIPS CPU at 40 MHz, 4.2-5.5V VDD, 36 I/O pins, 13 10-bit ADC channels, 2 PWM modules, 2+3 timers, EUSART, MSSP (SPI/I2C), 44-pin QFN package, and -40 C to +85 C industrial temperature grade. These specs define its position as a cost-effective 5V 8-bit MCU for industrial sensor designs.
Is PIC18F4220T-I/ML suitable for battery-powered IoT sensor designs?
The PIC18F4220T-I/ML is suitable for line-powered or USB-powered industrial sensors but is not optimal for battery-powered IoT nodes. Its 4.2V minimum VDD excludes 3V coin-cell operation, and its nanoWatt idle current is higher than the PIC18F46K20's XLP nanoWatt. For battery IoT, choose the PIC18F46K20-I/ML or PIC18F25K40-I/ML with sub-100 nA sleep current.

Engineering reference data for PIC18F4220T-I/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC18F4220T-I/ML for cost-sensitive industrial 5V sensor designs with C firmware under 2,500 lines where 4 KB Flash and 512 bytes RAM are sufficient. Pick the PIC18F4420T-I/ML when you need firmware headroom (16 KB Flash) for the same 44-pin QFN footprint. Pick the PIC18F4520T-I/ML for full-featured designs with graphics, USB, or networking stacks needing 32 KB Flash. Pick the PIC18F46K20T-I/ML for battery-powered or extended-temperature applications where XLP nanoWatt and 64 KB Flash matter. All four parts share the same 44-pin QFN (ML) package and pinout, enabling PCB layout reuse across the PIC18F4220/4320/4420/4520/46K20 family.

Comparison with Alternatives

Parameter This Product PIC18F4420T-I/ML PIC18F4520T-I/ML PIC18F46K20T-I/ML PIC18F4320T-I/ML
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 44-pin QFN (ML) 44-pin QFN (ML) - same 44-pin QFN (ML) - same 44-pin QFN (ML) - same 44-pin QFN (ML) - same
Program Memory (Flash) 4 KB 16 KB 32 KB 64 KB 8 KB
Data SRAM 512 bytes 768 bytes 1.5 KB 3.6 KB 512 bytes
Data EEPROM 256 bytes 256 bytes 256 bytes 1 KB 256 bytes
Maximum CPU Speed 40 MHz (10 MIPS) 40 MHz (10 MIPS) 40 MHz (10 MIPS) 64 MHz (16 MIPS) 40 MHz (10 MIPS)
Supply Voltage 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 1.8 V to 5.5 V 4.2 V to 5.5 V
I/O Pins 36 36 36 36 36
ADC 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 14 channels 10-bit, 13 channels
Operating Temperature -40 C to +85 C (Industrial) -40 C to +85 C (Industrial) -40 C to +85 C (Industrial) -40 C to +125 C (Extended) -40 C to +85 C (Industrial)

Key Differentiators

  • Legacy PIC18 baseline with broad code base and tool support (vs PIC18F46K20T-I/ML)
  • Lower cost entry point with adequate Flash for small firmware (vs PIC18F4320T-I/ML)
  • True 5V VDD tolerance without voltage translation (vs PIC18F46K20T-I/ML)

Design Notes

The PIC18F4220T-I/ML's 44-pin QFN package dissipates heat through the exposed thermal pad (EP) on pin 44. Solder the EP to a PCB copper pour of at least 0.5 square inches connected to ground. For industrial sensor designs at 40 MHz and 5 V, the device draws approximately 10-15 mA active, giving sub-100 mW dissipation that the QFN handles without active cooling. Always verify EP-to-ground continuity with a 4-wire milliohm measurement during PCB QA.

Place 0.1 uF ceramic decoupling capacitors as close as possible (within 3 mm) to each VDD pin (pins 18 and 37), plus a bulk 10 uF tantalum or aluminum polymer capacitor near the IC. AVdd (pin 42) and AVss (pin 41) require an RC low-pass filter (10 ohm + 0.1 uF) to keep ADC reference noise below 1 LSB. The nanoWatt technology enables idle currents under 1 uA when peripherals are gated off - refer to datasheet section on Sleep modes for proper peripheral disable sequencing.

Route the ICSP pins RB6/PGC (pin 25) and RB7/PGD (pin 26) directly to a 6-pin header (0.1 inch pitch) for in-circuit programming and debug. Keep the trace length under 50 mm and add 4.7 kohm pullups to VDD on PGC/PGD to prevent programming glitches. The MCLR/VPP pin (pin 27) requires a 10 kohm pullup to VDD and a 100 nF capacitor to ground for in-circuit programming. Avoid running high-current traces under the QFN's exposed pad to maintain ground integrity.

Common pitfalls with the PIC18F4220T-I/ML include: (1) forgetting to configure the oscillator mode bits in CONFIG1H for the correct clock source, (2) leaving the WDT enabled in production firmware without periodic clear, causing unintended resets, (3) using ADC without adequate acquisition time leading to inaccurate conversions, and (4) failing to set the BOR (brown-out reset) voltage threshold to match 5V operation. Always set CONFIG2L with the proper BOR level and CONFIG1H with HS or XT oscillator mode for 40 MHz crystals.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page. Industrial temperature grade (-40 C to +85 C). Not AEC-Q100 qualified - choose PIC18F46K20 automotive variants for automotive applications.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC18F4220T-I/ML PIC18F4420T-I/ML PIC18F4520T-I/ML PIC18F46K20T-I/ML PIC18F4320T-I/ML PIC18F 8-bit microcontroller MCU Harvard architecture RISC nanoWatt technology Flash memory EEPROM SRAM 10-bit ADC EUSART MSSP SPI I2C PWM CCP QFN-44 RoHS ICSP MPLAB X IDE XC8 compiler
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