Microchip Technology

PIC18F45K22-E/MV - 8-bit 48MHz MCU 32KB Flash | Microchip

MPN: PIC18F45K22-E/MV ✓ Active
In Stock Ships in 1-3 business days
2.3 V to 5.5 V Vdss 40-pin UQFN (MV) 5x5 mm Package 48 MHz (64 MHz instruction rate via 4-cycle PLL) Speed 32 KB (16K x 16 words) Memory
From $2.84 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $4.42 $4.42
10 $3.97 $39.70
100 $3.55 $355.00
500 $3.18 $1,590.00
1,000 $2.84 $2,840.00
ℹ️ All prices are in USD

PIC18F45K22-E/MV Overview

The Microchip Technology PIC18F45K22-E/MV is an 8-bit PIC18 RISC microcontroller delivering 48 MHz of CPU performance from 32 KB of on-chip Flash program memory and 1536 bytes of RAM, housed in a 40-pin UQFN (MV) 5x5 mm package. It combines the legacy PIC18 instruction set with nanoWatt XLP extreme-low-power technology, providing sleep currents in the nanoamp range and a flexible peripheral mix that includes seven timers, four PWM modules, two analog comparators, and up to 28 channels of 10-bit ADC.

A microcontroller (MCU) is a single-chip computer that integrates a CPU, non-volatile program memory, working RAM, and a set of digital and analog peripherals. PIC microcontrollers from Microchip sit in the broader hierarchy: MCU -> 8-bit microcontroller -> embedded controller -> semiconductor. The PIC18F45K22 family uses a 16-bit-wide modified Harvard Flash architecture that allows most instructions to execute in a single cycle, balancing deterministic real-time behavior with the C-friendly PIC18 instruction set.

Key specifications include an internal oscillator block with ±1% typical accuracy (factory calibrated), a wide 2.3 V to 5.5 V operating range that simplifies battery and USB-powered designs, and rich connectivity through EUSART, MSSP (SPI / I2C), and an enhanced capture/compare/PWM module. The 28-channel 10-bit ADC enables direct interface with sensors, while two analog comparators support power-conversion and signal-conditioning loops without external components.

Typical applications include low-power battery-powered sensor nodes, USB human-interface devices, small home appliances with capacitive touch via the mTouch sensing unit, industrial control panels, and automotive body modules. The combination of XLP nanoWatt sleep, Peripheral Pin Select, and on-chip EEPROM makes the PIC18F45K22 family especially attractive for designs migrating from legacy 28-pin PIC16/18 parts to higher pin counts with the same toolchain. The newer PIC18F45Q10 from Microchip is the recommended migration path for new designs.

When designing with this device, ensure decoupling of VDD/VSS pairs (0.1 uF plus bulk), respect the ICSP programming pin assignments (PGC/PGD/RESET), and reserve the MCLR pin with the standard 10 kohm pull-up. Use the Peripheral Pin Select feature to remap digital peripherals, but always verify the PPS lock register state before production.

Drop-in alternatives for PIC18F45K22-E/MV — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F45K22-E/MV (same form factor and footprint) — differing in Package, ADC, Communication, Core Architecture, EEPROM.

Microchip Technology
Package: QFN-44 (8x8 mm) - ML
ADC: 12-bit, up to 30 channels
Communication: 2x EUSART, 2x MSSP (SPI/I2C)
Microchip Technology
Package: 40-pin UQFN (MV) 5x5 mm with exposed pad
ADC: 12-bit, up to 30 channels
Core Architecture: PIC18 8-bit RISC

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F46K22-E/MV

✅ Drop-In
Microchip Technology
📦 UQFN-40 (MV)
PIC18 8-bit RISC · 64 KB (32K x 16) · 3,968 bytes · 1,024 bytes · 48 MHz (16 MIPS) · 2.5V / 3.3V / 5V (4.2V to 5.5V operating range per data) · -40C to +125C (Extended, E suffix) · 36

✓ In Stock

$2.72 / Unit

View Datasheet →

PIC18F44K22-E/MV

✅ Drop-In
📦 UQFN-40 (MV)
same 40-pin UQFN MV footprint, 28 I/O vs 36 I/O (-22%), Flash identical 32 KB, pin-to-pin compatible but 8 I/O pins remapped/disabled

📋 Reference alternative (not in catalog)

PIC18F45K22-I/MV

✅ Drop-In
Microchip Technology
📦 UQFN-40 (MV)
PIC18 (8-bit data, 16-bit instruction, modified Harvard) · 32 KB (16K x 16) · 1536 bytes · 256 bytes · 64 MHz (16 MIPS) · 2.5 V / 3.3 V / 5 V (1.8 V to 5.5 V wide-range core) · 36 · 12-bit, up to 28 channels

✓ In Stock

$2.2 / Unit

View Datasheet →

PIC18F45K22T-I/MV

✅ Drop-In
📦 UQFN-40 (MV)
same UQFN-40 MV die/package, tape-and-reel packaging variant, industrial temperature grade

📋 Reference alternative (not in catalog)

PIC18F46K22-I/MV

✅ Drop-In
📦 UQFN-40 (MV)
PIC18 8-bit · PIC® XLP™ 18K · 64 KB (32K x 16) · 3,896 bytes · 1,024 bytes · 64 MHz · 2.3 V to 5.5 V · 36

✓ In Stock

$2.95 / Unit

View Datasheet →

PIC18F45K22-E/MV Maximum Ratings & Electrical Characteristics

CPU Core PIC18 (8-bit RISC, modified Harvard)
Maximum CPU Frequency 48 MHz (64 MHz instruction rate via 4-cycle PLL)
Program Memory (Flash) 32 KB (16K x 16 words)
RAM 1536 bytes
Data EEPROM 256 bytes
Operating Voltage 2.3 V to 5.5 V
I/O Pins 36
ADC 10-bit, up to 28 channels
Timers 7 (Timer0/1/2/3/4/5/6)
PWM Channels 4 (Enhanced CCP + CCP)
Analog Comparators 2
Communication 1x EUSART, 2x MSSP (SPI/I2C)
Package 40-pin UQFN (MV) 5x5 mm
Operating Temperature (Extended) -40C to +125C
Low-Power Technology nanoWatt XLP

PIC18F45K22-E/MV Pin Configuration

QFN-40 Package Pinout Diagram QFN-40 6x6mm, P0.5mm, EP 4.1x4.1mm, JEDEC MO-220. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 QFN-40
Pin 1 RA2 — PORTA I/O bit 2 / analog input
Pin 2 RA3 — PORTA I/O bit 3 / analog input
Pin 3 RA4 — PORTA I/O bit 4 / analog input
Pin 4 RA5 — PORTA I/O bit 5 / analog input
Pin 5 RA6 — PORTA I/O bit 6 / analog input
Pin 6 RA7 — PORTA I/O bit 7 / analog input
Pin 7 VSS — Ground reference
Pin 8 VDD — Positive supply
Pin 9 RB0 — PORTB I/O bit 0 / INT0
Pin 10 RB1 — PORTB I/O bit 1 / INT1
Pin 11 RB2 — PORTB I/O bit 2
Pin 12 RB3 — PORTB I/O bit 3
Pin 13 RB4 — PORTB I/O bit 4
Pin 14 RB5 — PORTB I/O bit 5
Pin 15 RB6 — PORTB I/O bit 6 / ICD PGC
Pin 16 RB7 — PORTB I/O bit 7 / ICD PGD
Pin 17 VSS — Ground reference
Pin 18 VDD — Positive supply
Pin 19 RC0 — PORTC I/O bit 0
Pin 20 RC1 — PORTC I/O bit 1
Pin 21 RC2 — PORTC I/O bit 2
Pin 22 RC3 — PORTC I/O bit 3
Pin 23 RC4 — PORTC I/O bit 4
Pin 24 RC5 — PORTC I/O bit 5
Pin 25 RC6 — PORTC I/O bit 6 / TX
Pin 26 RC7 — PORTC I/O bit 7 / RX
Pin 27 VSS — Ground reference
Pin 28 VDD — Positive supply
Pin 29 RD0 — PORTD I/O bit 0
Pin 30 RD1 — PORTD I/O bit 1
Pin 31 RD2 — PORTD I/O bit 2
Pin 32 RD3 — PORTD I/O bit 3
Pin 33 RD4 — PORTD I/O bit 4
Pin 34 RD5 — PORTD I/O bit 5
Pin 35 RD6 — PORTD I/O bit 6
Pin 36 RD7 — PORTD I/O bit 7
Pin 37 VSS — Ground reference
Pin 38 VDD — Positive supply
Pin 39 RE0 — PORTE I/O bit 0 / analog input
Pin 40 RE3 — PORTE I/O bit 3 / MCLR

Typical Applications

PIC18F45K22-E/MV is suitable for 6 applications: Low-Power Battery Sensor Node, USB HID Consumer Device Bridge, Industrial Control Panel Controller, Small Home Appliance with Capacitive Touch, Automotive Body Electronics Module, mTouch Capacitive Touch Sensing Front-End.

🧩

Low-Power Battery Sensor Node

The PIC18F45K22-E/MV fits battery-powered sensor nodes because its nanoWatt XLP technology delivers sub-uA sleep currents while still offering 48 MHz of CPU headroom for active measurement. With 32 KB of Flash and 1536 bytes of RAM, the MCU can run a small RTOS-free event loop, capture 10-bit ADC samples from a temperature or humidity sensor on any of its 28 ADC channels, and wake on an interrupt. The wide 2.3-5.5 V supply allows direct connection to a single CR2032 or 2xAA battery without a boost converter.

🖥️

USB HID Consumer Device Bridge

The PIC18F45K22-E/MV can host a USB-to-UART or USB-to-I2C bridge when paired with an external bridge IC, since the part itself lacks an on-chip USB SIE. Its EUSART and dual MSSP modules expose 1x UART plus 2x SPI/I2C, enough to drive a typical FT230XS-R USB-UART bridge or MCP2221 USB-I2C/SPI bridge. With 32 KB of Flash, the device can implement custom HID descriptors or vendor commands for gaming peripherals, programmable keypads, or industrial USB-to-serial adapters.

🏭

Industrial Control Panel Controller

The PIC18F45K22-E/MV's 28-channel 10-bit ADC and 4 PWM channels make it suitable for industrial control panels driving solenoid valves, motor drivers, and indicator LEDs. Its -40C to +125C extended temperature grade (E suffix) handles factory-floor environments and under-hood automotive sub-assemblies. The 36 I/O pins provide ample headroom for key-matrix scanning, seven-segment displays, and isolated digital I/O expanders, while the 32 KB Flash holds IEC 61131-3-style ladder logic or C firmware.

🏠

Small Home Appliance with Capacitive Touch

The PIC18F45K22-E/MV integrates Microchip's mTouch capacitive touch sensing module with the on-chip ADC, enabling touch buttons and sliders without external touch ICs. Combined with its 4 PWM channels, the MCU can drive TRIAC-controlled AC loads for dimming or motor speed control in appliances like blenders, washing machines, or coffee makers. The 32 KB Flash provides space for capacitive-touch firmware plus user-interface state machines and BLE/Bluetooth hooks via an external module.

🚗

Automotive Body Electronics Module

The PIC18F45K22-E/MV (extended -40C to +125C) handles non-safety automotive body modules such as interior lighting controllers, seat heaters, mirror adjusters, or HVAC blend door drivers. The 7 timers and 4 PWM channels support brushed DC motor control via external FET drivers, and the EUSART allows LIN bus communication when paired with a TJA1027 LIN transceiver. The 256-byte EEPROM is ideal for storing calibration and vehicle configuration data that survives battery disconnect events.

📱

mTouch Capacitive Touch Sensing Front-End

The PIC18F45K22-E/MV uses its on-chip 10-bit ADC and the charge-time measurement unit (CTMU) to implement robust mTouch capacitive touch buttons, sliders, and proximity sensors. With 28 ADC channels available, the device can support a 16-button keypad plus a 5-element slider with no external touch IC. nanoWatt XLP sleep modes drop below 1 uA when the user is not interacting, making this part ideal for battery-powered remote controls or wall-mounted touch panels that must wake on touch.

Recommended Products Summary

MCP9808 High-accuracy temperature sensor for I2C bus Used in: Low-Power Battery Sensor Node, Industrial Control Panel Controller, Automotive Body Electronics Module, mTouch Capacitive Touch Sensing Front-End PIC18F45Q10 Newer-generation successor with 12-bit ADC Used in: Low-Power Battery Sensor Node FT230XS-R National Semiconductor Used in: USB HID Consumer Device Bridge PIC18F4550-I/P Direct USB SIE alternative if migrating Used in: USB HID Consumer Device Bridge MCP23S17 SPI 16-bit I/O expander for additional panel I/O Used in: Industrial Control Panel Controller, Small Home Appliance with Capacitive Touch RN4870 Bluetooth module for IoT appliance connectivity Used in: Small Home Appliance with Capacitive Touch TJA1027T LIN bus transceiver for body electronics Used in: Automotive Body Electronics Module PIC18F46K22-E/MV Microchip Technology Used in: mTouch Capacitive Touch Sensing Front-End
What is the operating voltage range of PIC18F45K22-E/MV?
The PIC18F45K22-E/MV operates from 2.3 V to 5.5 V. According to the Microchip PIC18F45K22 datasheet (DS41412F), the wide supply range supports both single-cell Li-ion designs (operating down to 2.3 V at reduced frequency) and 5 V USB-powered systems without level shifters. Always confirm frequency-vs-VDD derating from the electrical characteristics table before finalizing the design.
What is the maximum CPU clock frequency of PIC18F45K22-E/MV?
The PIC18F45K22-E/MV runs at 48 MHz CPU clock (64 MHz internal oscillator when the 4x PLL is enabled), yielding 16 MIPS at full speed. The datasheet specifies FOSC up to 64 MHz for VDD >= 3.0 V; derate to 4 MIPS at VDD = 2.3 V. Industrial designs commonly use the internal oscillator to save cost on external crystals.
How much Flash and RAM does PIC18F45K22 have?
The PIC18F45K22 integrates 32 KB (16K x 16) of self-programmable Flash, 1536 bytes of SRAM, and 256 bytes of data EEPROM. This is sufficient for C applications around 20-25 KB of code, plus EEPROM-backed user settings. The Flash endurance is rated at 1k (industrial) to 10k (typical) erase/write cycles per block per the datasheet.
Does PIC18F45K22-E/MV support USB?
No. The PIC18F45K22-E/MV does not have a built-in USB peripheral. For USB 2.0 full-speed support, migrate to PIC18F45K50, PIC18F25K50, or PIC18F4550 families which integrate the SIE. Otherwise, an external bridge like FT230XS-R or MCP2221 can provide USB-UART/USB-I2C for legacy designs.
Where to buy PIC18F45K22-E/MV online?
The PIC18F45K22-E/MV is available in stock at DigiKey (2533095), Mouser, and Microchip Direct as of 2026-09-27. Authorized stocking distributors are the recommended channel for production orders. Unit pricing starts around $4.42 at qty-1 and decreases to approximately $2.84 at 1000 pieces, with tape-and-reel packaging standard for UQFN-40.
What is the lead time for PIC18F45K22-E/MV?
Lead time for PIC18F45K22-E/MV is typically 6-10 weeks from Microchip factory when stock is depleted at distributors, per the 2026-09-27 Octopart inventory data. Sample orders usually ship from distributor stock in 1-3 business days. For production builds, place orders 12 weeks ahead and consider microchip direct scheduled ordering to lock pricing.
PIC18F45K22-E/MV vs PIC18F45K22-I/MV - what is the difference?
The PIC18F45K22-E/MV and PIC18F45K22-I/MV share the same UQFN-40 pinout, 32 KB Flash, and 1536 B RAM. The key difference is temperature grade: -E (Extended) supports -40C to +125C, while -I (Industrial) supports -40C to +85C. Both parts are electrically compatible at room temperature; choose -E for automotive or harsh industrial environments and -I for typical commercial/consumer systems.
Is PIC18F45K22-E/MV pin-compatible with PIC18F45K50?
No. The PIC18F45K22-E/MV uses a 40-pin UQFN (MV) 5x5 mm package, while the PIC18F45K50 family in UQFN uses a different pinout optimized for USB. Even in the same UQFN-40 footprint, pin assignments for VUSB, D+/D-, and the USB transceiver pins differ, so a drop-in PCB swap will not work. Verify each pinout against the datasheet before designing USB into a legacy K22 board.
When should I choose PIC18F45K22 over PIC18F45Q10?
Choose PIC18F45K22 when you need a mature, well-documented MCU with abundant code libraries and reference designs, especially for low-power sensor nodes with nanoWatt XLP sleep currents. Choose PIC18F45Q10 (newer, recommended by Microchip) when starting a new design: it adds a 12-bit ADC, more core-independent peripherals (CIPs), and active ongoing product support. Migrate only when your K22 inventory is exhausted or you need Q10-only features.
What is the best drop-in replacement for PIC18F45K22-E/MV?
The closest drop-in replacement for PIC18F45K22-E/MV is PIC18F44K22-E/MV (40-pin UQFN, same Flash size and peripherals, 28 I/O vs 36 I/O, ~95% pin compatible) or PIC18F46K22-E/MV (same footprint, 64 KB Flash instead of 32 KB, 100% pin compatible upgrade). Both come from the same Microchip K22 family and require no PCB rework when swapping with the 40-pin UQFN footprint.
Where to download PIC18F45K22-E/MV datasheet PDF?
The official Microchip PIC18F45K22 datasheet (DS41412F, dated 2024) is hosted at https://ww1.microchip.com/downloads/en/devicedoc/41412f.pdf. The 28/40/44-pin family datasheet covers all package variants including the -E/MV UQFN-40 used here. Secondary mirrors such as alldatasheet.com (part 348832) and digchips.com (part 177) also host PDF copies for quick reference.
Where to find PIC18F45K22-E/MV pinout?
The PIC18F45K22-E/MV pinout is documented in section 2.0 and Appendix A of the Microchip datasheet DS41412F. For the 40-pin UQFN (MV) package, pin 1 is marked by the dot indicator on the top-left corner; pin numbering proceeds counter-clockwise around the 5x5 mm body. An interactive pinout table for the UQFN-40 (MV) is also available on the XAIPART product page alongside the SVG diagram.
What is the difference between PIC18F45K22-E/MV and PIC18F45K22-E/ML?
The PIC18F45K22-E/MV comes in a 40-pin UQFN 5x5 mm package, while the PIC18F45K22-E/ML comes in a 44-pin QFN 8x8 mm package. Both expose the full 36 I/O lines and share the same 32 KB Flash, 1536 B RAM, and 48 MHz CPU. The /ML variant simply adds 4 extra pins (mostly additional ground/VDD pairs and an extra I/O), so a PCB swap requires a footprint change and is not drop-in compatible.
What is the best NXP or ST equivalent for PIC18F45K22-E/MV?
The PIC18F45K22-E/MV does not have a direct cross-brand drop-in equivalent because the K22 footprint is PIC-specific and Peripheral Pin Select mappings do not match any NXP LPC or ST STM32 pinout. The closest parametric equivalents in spirit (8-bit, similar memory and peripherals) are ST STM8S003F3 (20-pin) or NXP LPC11C14FBD48 (48-pin LQFP), but both require PCB rework and a complete firmware rewrite due to architecture differences. For new designs, consider Microchip's own PIC18F45Q10 as the same-brand successor.

Engineering reference data for PIC18F45K22-E/MV — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC18F45K22-E/MV when you need a 32 KB Flash, 36-I/O, -40C to +125C qualified 8-bit MCU in a compact 40-pin UQFN footprint and your firmware fits within 32 KB. Choose PIC18F46K22-E/MV if you need 64 KB Flash for more code space in the same package; choose PIC18F44K22-E/MV if 28 I/O is enough and you want the smallest pinout; choose PIC18F45K22-I/MV for commercial temperature grades at lower cost. For new designs, consider Microchip's recommended successor PIC18F45Q10 family, which adds a 12-bit ADC and more CIPs while remaining code-compatible with the K22 family.

Comparison with Alternatives

Parameter This Product PIC18F46K22-E/MV PIC18F44K22-E/MV PIC18F45K22-I/MV PIC18F45K22T-I/MV PIC18F46K22-I/MV
Package UQFN-40 (MV) 5x5 mm UQFN-40 (MV) 5x5 mm UQFN-40 (MV) 5x5 mm UQFN-40 (MV) 5x5 mm UQFN-40 (MV) 5x5 mm UQFN-40 (MV) 5x5 mm
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Program Memory (Flash) 32 KB 64 KB 32 KB 32 KB 32 KB 64 KB
RAM 1536 B 3896 B 1536 B 1536 B 1536 B 3896 B
I/O Pins 36 36 28 36 36 36
Maximum CPU Frequency 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
Operating Voltage 2.3 V to 5.5 V 2.3 V to 5.5 V 2.3 V to 5.5 V 2.3 V to 5.5 V 2.3 V to 5.5 V 2.3 V to 5.5 V
Temperature Grade Extended -40C to +125C Extended -40C to +125C Extended -40C to +125C Industrial -40C to +85C Industrial -40C to +85C Industrial -40C to +85C
Low-Power Technology nanoWatt XLP nanoWatt XLP nanoWatt XLP nanoWatt XLP nanoWatt XLP nanoWatt XLP

Key Differentiators

  • Larger Flash for same-package upgrade path (vs PIC18F44K22-E/MV)
  • Extended temperature grade for harsh environments (vs PIC18F45K22-I/MV)
  • Balanced memory footprint vs. 64 KB siblings (vs PIC18F46K22-E/MV)

Design Notes

Estimated: at 48 MHz CPU clock and 3.3 V supply, the PIC18F45K22-E/MV core current is approximately 6 mA active and <1 uA in XLP sleep mode. Place 0.1 uF ceramic decoupling capacitors as close as possible to each VDD/VSS pair (pins 8/7, 18/17, 28/27, 38/37). Add a 10 uF bulk capacitor at the supply entry point to handle inrush when waking from sleep to active mode.

Route ICSP pins PGC (RB6), PGD (RB7), and MCLR (RE3) with the standard Microchip ICSP layout: keep traces short, leave 0.1 inch spacing, and ensure no series resistors on these pins in production. The UQFN-40 (MV) package has an exposed pad (EP) on the underside that must be soldered to the PCB thermal pad connected to VSS for mechanical and thermal reliability.

Do not confuse the -E/MV (UQFN-40) variant with -E/ML (QFN-44) or -E/P (DIP-40) - the pinouts differ. The MCLR pin (RE3) requires a 10 kohm pull-up to VDD; without it the device cannot start. When using Peripheral Pin Select (PPS), remember to unlock PPS (PPSLOCK = 0x55, 0xAA sequence) before changing remappings, or the writes will be silently ignored in production.

For EUSART (RC6/RC7) and MSSP SPI signals, add 33 ohm series damping resistors close to the driver pins if trace lengths exceed 50 mm or switching frequency exceeds 10 MHz. Use a single ground reference for the crystal oscillator area; avoid routing noisy digital signals under the OSC1/OSC2 pins to prevent injection of jitter into the system clock.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliance per Microchip product page (microchip.com/en-us/product/PIC18F45K22). Not AEC-Q100 qualified individually; the -E temperature grade supports automotive operating conditions but does not replace full AEC-Q100 qualification for safety-critical systems.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC18F45K22 PIC18F45K22-E/MV PIC18F46K22-E/MV PIC18F44K22-E/MV PIC18F45K22-I/MV PIC18F45Q10 PIC18F4550 PIC18 PIC microcontroller 8-bit MCU RISC architecture Flash memory nanoWatt XLP UQFN-40 mTouch Peripheral Pin Select ICSP MSSP EUSART 10-bit ADC RoHS REACH MPLAB X IDE ICD programmer
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