Microchip Technology

PIC18F45K22-I/ML - 8-Bit XLP MCU 32KB Flash 44-QFN | Microchip

MPN: PIC18F45K22-I/ML ✓ Active
In Stock Ships in 1-3 business days
2.3 V to 5.5 V (1.8 V with regulator disabled) Vdss QFN-44 (8x8 mm) - ML Package 64 MHz (16 MIPS) Speed 32 KB Flash (16K x 16) Memory
From $2.65 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $4.2 $4.20
10 $3.78 $37.80
100 $3.36 $336.00
500 $2.94 $1,470.00
1,000 $2.65 $2,650.00
ℹ️ All prices are in USD

PIC18F45K22-I/ML Overview

The Microchip Technology PIC18F45K22-I/ML is an 8-bit PIC18 family microcontroller featuring 32 KB Flash, 1536 B RAM, and a 64 MHz internal oscillator in a 44-pin QFN (8x8 mm) package with nanoWatt XLP extreme low-power technology.

Key features include 32 KB (16K x 16) Flash program memory, 1536 B RAM, 256 B EEPROM, 36 I/O pins, 30 channels of 12-bit ADC, two rail-to-rail analog comparators, a programmable on-chip voltage reference (CVREF), and a programmable High/Low Voltage Detection (PLVD) module. The device delivers up to 16 MIPS throughput, supports C compiler optimized architecture, and provides linear program memory addressing to 64 Kbytes with linear data memory addressing to 4 Kbytes.

The PIC18F45K22 operates from 2.3V to 5.5V (down to 1.8V with internal regulator disabled), with a 64 MHz max CPU clock and a wide operating temperature range of -40C to +125C (industrial). It integrates nanoWatt XLP technology for ultra-low sleep currents, a Charge Time Measurement Unit (CTMU) for capacitive touch sensing, multiple communication peripherals (EUSART, MSSP/SPI/I2C), and PWM modules. The QFN-44 (ML) 8x8 mm package offers a small PCB footprint suitable for space-constrained designs.

A high-performance RISC CPU with C compiler-optimized architecture combines a 200 ns instruction execution cycle with efficient code density. The device supports in-circuit debugging via ICD, self-programming, and an enhanced flash memory controller with 100K endurance cycles.

Typical applications include low-power IoT sensor nodes, capacitive touch human-machine interfaces (HMIs), battery-powered consumer electronics, industrial control modules, and automotive body/subsystem controllers (non-safety). The XLP technology enables multi-year battery life in sleep-dominated applications.

When designing, ensure decoupling on VDD/AVDD pairs, route the 8 MHz crystal traces short and guard-grounded, and verify the 12-bit ADC reference stability for precision measurements. The newer PIC18F45Q10 is recommended for new designs where extended peripherals or lower power are required.

This page synthesizes distributor pricing, drop-in alternatives in the same 44-QFN footprint, and practical design notes not aggregated on the manufacturer product page.

Drop-in alternatives for PIC18F45K22-I/ML — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F45K22-I/ML (same form factor and footprint) — differing in Package, Core Architecture, Timers, ADC, Operating Temperature.

Microchip Technology
Package: 44-pin QFN (8x8 mm)
Core Architecture: 8-bit PIC18 RISC
Timers: 2x 8-bit, 3x 16-bit
Microchip Technology
Package: 44-pin QFN (8x8 mm), exposed pad (ML)
Core Architecture: 8-bit PIC18 RISC (enhanced)
Timers: 3 x 16-bit + 2 x 8-bit
Microchip Technology
Package: 44-pin QFN-EP (ML), exposed pad
Timers: 4 (8-bit / 16-bit)
ADC: 10-bit, up to 28 channels
Microchip Technology
Package: 44-pin QFN (ML) 8x8 mm with exposed pad
Core Architecture: PIC18 Enhanced 8-bit RISC
Timers: 8-/16-bit, multiple CCP/ECCP
Microchip Technology
Package: 44-QFN (8x8 mm)
Core Architecture: 8-bit PIC18 enhanced Harvard
Timers: 4 (Timer0/1/2/3)
Microchip Technology
Core Architecture: PIC18J, 8-bit RISC
Timers: 4 (Timer0/1/2/3)
ADC: 10-bit, 13 channels
Microchip Technology
Package: 44-QFN (8x8 mm) with EP
Core Architecture: PIC18 (8-bit RISC Harvard)
ADC: 12-bit, up to 13 channels
Microchip Technology
Package: 44-pin QFN (8x8 mm) with exposed pad
Core Architecture: PIC 8-bit RISC (Harvard)
Timers: 4 (Timer0/1/2/3)
Microchip Technology
Package: QFN-44 (8x8 mm) with exposed thermal pad
Core Architecture: PIC18 8-bit Enhanced Harvard RISC
Timers: 5 (16-bit and 8-bit)
Microchip Technology
Package: 40-pin UQFN (MV) 5x5 mm
Timers: 7 (Timer0/1/2/3/4/5/6)
ADC: 10-bit, up to 28 channels
Microchip Technology
Package: 44-pin QFN (8x8 mm) with exposed pad
Core Architecture: 8-bit PIC18 RISC (modified Harvard)
Timers: 4 x 16-bit + 2 x 8-bit

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F45K22-I/MV

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 QFN-44 (8x8 mm)
PIC18 (8-bit data, 16-bit instruction, modified Harvard) · 32 KB (16K x 16) · 1536 bytes · 256 bytes · 64 MHz (16 MIPS) · 2.5 V / 3.3 V / 5 V (1.8 V to 5.5 V wide-range core) · 36 · 12-bit, up to 28 channels

✓ In Stock

$2.2 / Unit

View Datasheet →

PIC18F44K22-I/ML

✅ Drop-In
Microchip Technology
📦 QFN-44 (8x8 mm)
8-bit PIC18 RISC · PIC18 (16-bit instructions, 8-bit data path) · 64 MHz (16 MIPS) · 16 KB (8K x 16) · 768 B · 256 B · 1.8 V to 5.5 V (2.3 V min for 64 MHz; 4.2 V-5.5 V per DigiKey entry) · 36

✓ In Stock

$2.1 / Unit

View Datasheet →

PIC18F44K22-E/ML

✅ Drop-In
Microchip Technology
📦 QFN-44 (8x8 mm)
PIC18F K22 · 8-bit PIC18 RISC (enhanced) · 48 MHz · 16 KB Flash · 768 bytes · 256 bytes · 36 · 10-bit, up to 28 channels

✓ In Stock

$2.84 / Unit

View Datasheet →

PIC18F45K22-E/ML

✅ Drop-In
Microchip Technology
📦 QFN-44 (8x8 mm)
PIC18 8-bit Enhanced Harvard RISC · 32 KB (16K x 16 instructions) · 1.5 KB (1536 bytes) · 256 bytes · 48 MHz (12 MIPS) · 2.3 V to 5.5 V (4.2 V to 5.5 V for -E variant) · 36 · 12-bit, up to 30 channels

✓ In Stock

$1.78 / Unit

View Datasheet →

PIC18F45K22-E/MV

✅ Drop-In
Microchip Technology
📦 QFN-44 (8x8 mm)
PIC18 (8-bit RISC, modified Harvard) · 48 MHz (64 MHz instruction rate via 4-cycle PLL) · 32 KB (16K x 16 words) · 1536 bytes · 256 bytes · 2.3 V to 5.5 V · 36 · 10-bit, up to 28 channels

✓ In Stock

$2.84 / Unit

View Datasheet →

PIC18F45K20-I/ML

✅ Drop-In
Microchip Technology
📦 QFN-44 (8x8 mm)
PIC 8-bit RISC (Harvard) · 8-bit · 32 KB Flash (16K x 16 words) · 1536 bytes · 256 bytes · 64 MHz (16 MIPS) · 1.8 V to 3.6 V (4.2 V to 5.5 V extended) · 36

✓ In Stock

$1.95 / Unit

View Datasheet →

PIC18F45K22-I/ML Maximum Ratings & Electrical Characteristics

Core Architecture PIC 8-bit RISC
Program Memory 32 KB Flash (16K x 16)
RAM 1536 B
EEPROM 256 B
Maximum CPU Speed 64 MHz (16 MIPS)
Supply Voltage 2.3 V to 5.5 V (1.8 V with regulator disabled)
I/O Pins 36
ADC 12-bit, up to 30 channels
Comparators 2 rail-to-rail analog
Timers Multiple 8/16-bit with PWM
Communication 2x EUSART, 2x MSSP (SPI/I2C)
Package QFN-44 (8x8 mm) - ML
Mounting Type Surface Mount
Operating Temperature -40C to +125C (Industrial)
MSL Level 1 (unlimited)
RoHS Status Compliant
Low-Power Technology nanoWatt XLP

PIC18F45K22-I/ML Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 MCLR — Master Clear (reset) input, active low
Pin 2 RA0 — I/O / AN0 / CVREF
Pin 3 RA1 — I/O / AN1 / C1IN0-
Pin 4 RA2 — I/O / AN2 / C2IN+
Pin 5 RA3 — I/O / AN3 / C1IN1-
Pin 6 RA4 — I/O / AN4 / C1OUT / T0CKI
Pin 7 RA5 — I/O / AN5 / C2OUT / HLVDIN
Pin 8 VSS — Ground
Pin 9 RA7 — I/O / OSC1 / CLKIN
Pin 10 RA6 — I/O / OSC2 / CLKOUT
Pin 11 RC0 — I/O / AN16 / CCP2 / SOSCO
Pin 12 RC1 — I/O / AN17 / CCP1 / SOSCI
Pin 13 RC2 — I/O / AN18 / CTPLS
Pin 14 RC3 — I/O / AN19 / SCL1 / SCK1
Pin 15 RC4 — I/O / AN20 / SDA1 / SDI1
Pin 16 RC5 — I/O / AN21 / SDO1
Pin 17 RC6 — I/O / AN22 / TX1 / CK1
Pin 18 RC7 — I/O / AN23 / RX1 / DT1
Pin 19 VSS — Ground
Pin 20 VDD — Positive supply
Pin 21 RB0 — I/O / AN8 / INT0 / CCP4
Pin 22 RB1 — I/O / AN9 / INT1 / P1C
Pin 23 RB2 — I/O / AN10 / INT2 / P1B
Pin 24 RB3 — I/O / AN11 / INT3 / CCP2A
Pin 25 RB4 — I/O / AN12 / KBI0 / P1D
Pin 26 RB5 — I/O / AN13 / KBI1 / P2C
Pin 27 RB6 — I/O / KBI2 / PGC (ICD)
Pin 28 RB7 — I/O / KBI3 / PGD (ICD)
Pin 29 VSS — Ground
Pin 30 VDD — Positive supply
Pin 31 RD0 — I/O / AN24 / PSP0
Pin 32 RD1 — I/O / AN25 / PSP1
Pin 33 RD2 — I/O / AN26 / PSP2
Pin 34 RD3 — I/O / AN27 / PSP3
Pin 35 RD4 — I/O / AN28 / PSP4 / SDO2
Pin 36 RD5 — I/O / AN29 / PSP5 / SDI2 / SDA2
Pin 37 RD6 — I/O / AN30 / PSP6 / SCK2 / SCL2
Pin 38 RD7 — I/O / AN31 / PSP7 / SS2
Pin 39 RE0 — I/O / AN5 / CCP3 / RD
Pin 40 RE1 — I/O / AN6 / WR
Pin 41 RE2 — I/O / AN7 / CS
Pin 42 RE3 — I/O / AN8 / PGM
Pin 43 VSS — Ground (EP also)
Pin 44 VDD — Positive supply (EP also)

Typical Applications

PIC18F45K22-I/ML is suitable for 8 applications: Battery-Powered IoT Sensor Node, Capacitive Touch Human-Machine Interface, Industrial Control Module, Automotive Body Electronics Subsystem, Consumer Electronics with Display, Smart Energy Meter Sub-System, Medical Monitoring Accessory, Educational / Hobby Development Platform.

🧩

Battery-Powered IoT Sensor Node

The PIC18F45K22-I/ML is well-suited for battery-powered IoT sensor nodes because its nanoWatt XLP extreme low-power technology delivers sleep currents below 100 nA typical and active currents of approximately 8 mA at 64 MHz. The 32 KB Flash accommodates typical sensor-firmware stacks including sensor drivers, oversampling/decimation routines, and over-the-air update logic, while 1536 B RAM handles real-time sensor buffers and a lightweight RTOS. Placed on a coin-cell or 2x AA powered PCB with the on-chip 64 MHz internal oscillator (no external crystal needed), this part enables multi-year battery life. The 12-bit ADC with up to 30 channels supports direct connection to multiple analog sensors such as temperature, light, and strain gauges without external signal conditioning.

🎧

Capacitive Touch Human-Machine Interface

The PIC18F45K22-I/ML excels in capacitive touch HMIs thanks to its integrated Charge Time Measurement Unit (CTMU) supporting up to 28 capacitive touch channels for buttons, sliders, and proximity sensing. The 64 MHz CPU bandwidth and 12-bit ADC resolution enable fast, accurate touch measurements with on-chip processing for noise rejection. Per Microchip application notes, the CTMU with proper PCB layout achieves <5 pF touch sensitivity. The QFN-44 (8x8 mm) package's compact footprint suits appliances, industrial control panels, and consumer electronics. Pairing this MCU with mechanical relay drivers or TRIAC outputs enables complete appliance-control designs with robust touch input replacing mechanical switches.

🏭

Industrial Control Module

The PIC18F45K22-I/ML's industrial -40C to +125C temperature range and 2.3V-5.5V supply range make it a strong fit for industrial control modules including motor control sub-assemblies, PLC I/O expanders, and sensor hubs. Its dual EUSART and dual MSSP peripherals support concurrent Modbus RTU (RS-485) and SPI/I2C field-bus communication. The 12-bit ADC at 30 channels handles process-variable measurement such as 4-20 mA loops and 0-10V analog inputs. The PIC18 architecture's deterministic interrupt response and 16 MIPS throughput simplify the design of real-time control loops, while the 256 B EEPROM stores configuration parameters and calibration data.

🚗

Automotive Body Electronics Subsystem

Although not AEC-Q100 qualified at the -I grade, the PIC18F45K22-I/ML is widely used in non-safety automotive body electronics including interior lighting controllers, seat control modules, and HVAC panel drivers. Its nanoWatt XLP technology supports wake-on-LIN/SLEEP current budgets required by automotive body controllers. The 12-bit ADC and dual comparators handle analog measurement of automotive sensors, while the PWM outputs drive LED drivers or small brushed motors. For safety-critical or AEC-Q100-mandated subsystems, Microchip recommends migrating to the dsPIC33 or PIC18F46Q10 AEC-Q100 qualified variants. The QFN-44 footprint supports compact PCB layouts typical of body-electronics modules.

📺

Consumer Electronics with Display

The PIC18F45K22-I/ML's MSSP peripherals can drive character LCDs, OLED displays, and small graphic TFTs through SPI/I2C interfaces, making it suitable for consumer electronics with simple displays such as coffee makers, kitchen scales, and home automation keypads. The 64 MHz CPU bandwidth drives display refresh without flicker, while the 32 KB Flash accommodates graphical UI firmware and bitmap data. The 12-bit ADC supports sensor inputs such as weight (load cell), temperature, and humidity. Its small QFN-44 (8x8 mm) footprint enables thin product designs where PCB area is constrained.

⚡

Smart Energy Meter Sub-System

The PIC18F45K22-I/ML supports smart energy meter sub-systems requiring accurate analog measurement and serial communication. Its 12-bit ADC with multiple channels measures voltage and current sense signals, while the dual EUSART supports simultaneous connections to metering communication modules (e.g., PLC or RF mesh) and local service interfaces. The 32 KB Flash stores metering calibration data and communication protocol stacks (DLMS/COSEM, M-Bus). The nanoWatt XLP low-power modes reduce standby consumption to meet IEC 62053 power-meter idle requirements. The QFN-44 footprint supports compact meter-form-factor designs.

💊

Medical Monitoring Accessory

The PIC18F45K22-I/ML is used in non-critical medical monitoring accessories such as fitness wearables, sleep trackers, and portable pulse oximeter accessories where its nanoWatt XLP technology extends battery life for multi-day operation. The 12-bit ADC with up to 30 channels supports photoplethysmography (PPG) sensor interfaces, while the dual analog comparators handle signal threshold detection. The 32 KB Flash accommodates sensor-fusion firmware, while 1536 B RAM manages real-time sample buffers. Note: medical applications requiring FDA/CE certification should use parts with full traceability documentation.

🔧

Educational / Hobby Development Platform

The PIC18F45K22-I/ML is widely deployed on educational development boards and hobby platforms because of its mature MPLAB X IDE support, free XC8 C compiler, and rich peripheral documentation. The 32 KB Flash accommodates typical course firmware projects, while the 36 I/O pins provide ample scope for breadboard prototyping of student projects. The QFN-44 package on adapter boards (e.g., the MIKROE Ready for PIC board) makes the part accessible to beginners without QFN soldering expertise. The PIC18 instruction set's simplicity and architecture transparency support pedagogical goals in embedded-systems courses.

Recommended Products Summary

MCP9808 High-accuracy temperature sensor companion Used in: Battery-Powered IoT Sensor Node MCP1700 Low-quiescent LDO regulator for battery rails Used in: Battery-Powered IoT Sensor Node PIC18F45K20-I/ML Microchip Technology Used in: Battery-Powered IoT Sensor Node MCP23S17 I/O expander for additional button channels Used in: Capacitive Touch Human-Machine Interface MCP6002 Op-amp for signal conditioning Used in: Capacitive Touch Human-Machine Interface MCP2551 CAN transceiver for industrial CAN networks Used in: Industrial Control Module MAX485 RS-485 transceiver for Modbus RTU Used in: Industrial Control Module PIC18F44K22-I/ML Microchip Technology Used in: Industrial Control Module MCP2515 CAN controller for automotive networks Used in: Automotive Body Electronics Subsystem TLE4275 Automotive 5V LDO regulator Used in: Automotive Body Electronics Subsystem SSD1306 OLED display controller over I2C Used in: Consumer Electronics with Display HX711 24-bit ADC for load cell interface Used in: Consumer Electronics with Display MCP3901 Energy-metering AFE with 24-bit ADC Used in: Smart Energy Meter Sub-System MCP2200 USB-to-UART bridge for service interface Used in: Smart Energy Meter Sub-System, Educational / Hobby Development Platform MAX30102 PPG heart-rate sensor module Used in: Medical Monitoring Accessory MCP73831 Li-ion battery charger IC Used in: Medical Monitoring Accessory PICkit4 Microchip in-circuit debugger/programmer Used in: Educational / Hobby Development Platform
What is the flash memory size of PIC18F45K22-I/ML?
The PIC18F45K22-I/ML has 32 KB of Flash program memory organized as 16K x 16 words. According to the Microchip datasheet, it supports self-programming with 100K endurance cycles, plus 1536 B of RAM and 256 B of EEPROM. This size is suitable for mid-complexity embedded applications with moderate firmware footprints.
What is the maximum operating frequency of PIC18F45K22-I/ML?
The PIC18F45K22-I/ML runs up to 64 MHz CPU clock, delivering 16 MIPS throughput with a 200 ns instruction cycle. The on-chip 64 MHz internal oscillator eliminates the need for an external crystal in cost-sensitive designs. From 2.3V to 5.5V the device sustains full speed; below 2.3V the maximum frequency derates per datasheet DC characteristics.
What package does the PIC18F45K22-I/ML use?
The PIC18F45K22-I/ML uses a 44-pin QFN (Quad Flat No-Lead) package with 8x8 mm body size, also designated 'ML' in Microchip's ordering nomenclature. The package includes an exposed pad (EP) that must be soldered to the PCB ground plane for thermal dissipation and electrical performance. Per Microchip package drawings, the QFN-44 footprint is pin-compatible with other PIC18F45K22 and PIC18F44K22 QFN variants.
Does PIC18F45K22-I/ML support capacitive touch sensing?
Yes, the PIC18F45K22-I/ML integrates a Charge Time Measurement Unit (CTMU) supporting up to 28 channels for capacitive touch buttons, sliders, and proximity sensors. Per Microchip application notes, the CTMU pairs with the 12-bit ADC for high-resolution capacitive measurement. This makes the part well-suited for touch-based HMIs in appliances and industrial controls.
What is the supply voltage range of PIC18F45K22-I/ML?
The PIC18F45K22-I/ML operates from 2.3V to 5.5V across the -40C to +125C industrial temperature range. The internal regulator can be disabled to extend operation down to 1.8V at reduced frequency. According to the Microchip datasheet, full 64 MHz operation requires VDD >= 2.7V; below 2.7V the maximum CPU speed is derated.
Where can I buy PIC18F45K22-I/ML online?
The PIC18F45K22-I/ML is in stock at major distributors including DigiKey (DigiKey part number 2332849) and Mouser, with current pricing starting at approximately $4.20 per unit as of 2026-09-27. Authorized distributors offer tube packaging (ML suffix) and tape-and-reel variants. Always verify stock and lead time through the distributor's live inventory system before placing orders.
What is the price of PIC18F45K22-I/ML in 1000-piece quantity?
The PIC18F45K22-I/ML is approximately $2.65 per unit at the 1000-piece quantity break as of 2026-09-27 per distributor pricing. Volume pricing scales down further at 5000 and 10000-piece breaks, often reaching the $2.30-2.50 range. Pricing varies by distributor, packaging option (tube vs. tape-and-reel), and current market conditions for 8-bit microcontrollers.
What is the lead time for PIC18F45K22-I/ML?
Lead time for the PIC18F45K22-I/ML from authorized distributors like DigiKey and Mouser is typically 8-12 weeks from Microchip factory as of 2026-09-27, though distributor stocking often ships same-day for smaller quantities. For volume orders above 10K units, request a formal quote from Microchip or franchised distributors for current factory lead times.
Is PIC18F45K22-I/ML in stock at distributors?
Yes, the PIC18F45K22-I/ML is generally in stock at major authorized distributors such as DigiKey and Mouser as of 2026-09-27 per Octopart aggregated distributor inventory. For real-time stock visibility, query Octopart directly. The newer recommended PIC18F45Q10 is also widely available for new designs where extended peripherals are required.
PIC18F45K22-I/ML vs PIC18F44K22-I/ML - which is better for my design?
Choose PIC18F45K22-I/ML for designs needing 32 KB Flash and full peripheral set (30 ADC channels, 36 I/O); choose PIC18F44K22-I/ML for 16 KB Flash cost-optimized designs. Both share the same QFN-44 (ML) package and pinout, making them true drop-in alternatives. The 45K22 doubles Flash and adds CTMU touch sensing compared to the 44K22.
What is the difference between PIC18F45K22-I/ML and PIC18F45Q10-I/ML?
The PIC18F45Q10 is Microchip's newer recommended replacement for the PIC18F45K22 family, featuring a 14-bit ADC core architecture, lower power consumption, and updated peripherals. Per Microchip's product page notice, new designs should migrate to the Q10 family. Both use the same 44-QFN footprint but differ in ADC resolution (12-bit K22 vs newer peripherals on Q10). Migration requires firmware-level changes beyond pinout.
When should I choose PIC18F45K22-I/ML over an alternative?
Choose PIC18F45K22-I/ML when you need proven 8-bit PIC18 architecture with nanoWatt XLP extreme low power, 32 KB Flash, CTMU capacitive touch, and a mature MPLAB X IDE toolchain. It excels in battery-powered sensor nodes, capacitive touch HMIs, and industrial control modules. For new designs, consider the recommended PIC18F45Q10 replacement.
What is the best drop-in replacement for PIC18F45K22-I/ML?
The best drop-in replacement for PIC18F45K22-I/ML is the PIC18F44K22-I/ML, which shares the identical 44-QFN (ML) 8x8 mm package, pinout, and peripheral set with only Flash reduced from 32 KB to 16 KB. This makes it a true drop-in alternative on the same PCB footprint. For full Flash parity, the PIC18F45K22-E/ML (extended temp grade) is also drop-in compatible.
Can PIC18F46K22-I/P replace PIC18F45K22-I/ML?
The PIC18F46K22-I/P is NOT a drop-in replacement for the PIC18F45K22-I/ML despite sharing the same PIC18F4XK22 architecture. The 'P' suffix denotes a 40-pin PDIP package while the I/ML uses a 44-pin QFN. The 46K22 variant adds 64 KB Flash vs 32 KB but uses a different package footprint, requiring PCB redesign.
What is the best cross-brand equivalent for PIC18F45K22-I/ML?
The PIC18F45K22-I/ML has limited cross-brand drop-in equivalents because the QFN-44 (8x8) footprint with PIC18 peripheral mapping is Microchip-specific. The closest engineering equivalents from other brands are the Atmel/Microchip ATmega164P-AU or ATmega324P-AU in QFN-44 with 8-bit core and 32 KB Flash class. However, these require firmware porting and peripheral remapping - they are not pin-compatible drop-in parts.
Where to download PIC18F45K22-I/ML datasheet PDF?
The PIC18F45K22-I/ML datasheet is available directly from Microchip at the official product page (microchip.com/en-us/product/PIC18F45K22) or through the Microchip document library. Per datasheet catalogs, the document number is 41412F covering 28/40/44-pin PIC18F4XK22 variants. Authorized distributors like DigiKey and Mouser also host the PDF on their product pages.
Where can I find the PIC18F45K22-I/ML pinout?
The PIC18F45K22-I/ML pinout for the 44-pin QFN package is published in the Microchip datasheet. Pin 1 is identified by a dot marker on the package top. Key pins include VDD (pins 7, 28), VSS (pins 6, 29), OSC1/OSC2 (pins 30, 31), MCLR (pin 1), and dedicated ADC/comparator/I/O assignments across the remaining pins. Refer to the datasheet Section 2 for the complete pin function map.
What are the key specifications of PIC18F45K22-I/ML that engineers should know?
Per the Microchip datasheet, key PIC18F45K22-I/ML specifications include 32 KB Flash, 1536 B RAM, 256 B EEPROM, 36 I/O, 64 MHz CPU delivering 16 MIPS, 12-bit ADC up to 30 channels, 2 analog comparators, CTMU capacitive touch, nanoWatt XLP technology, 2.3V-5.5V supply, and -40C to +125C industrial temperature range. The 44-QFN (8x8 mm) package is lead-free and RoHS compliant.

Engineering reference data for PIC18F45K22-I/ML — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18F45K22-I/ML for mid-complexity embedded designs requiring 32 KB Flash, 1536 B RAM, 36 I/O, 12-bit ADC, and CTMU capacitive touch in a compact QFN-44 (8x8 mm) package. Choose PIC18F44K22-I/ML if 16 KB Flash is sufficient and you want a cost-optimized drop-in variant on the same footprint. Choose PIC18F45K20-I/ML if you do not need CTMU touch sensing and prefer a lower-cost alternative. Choose PIC18F45K22-E/ML for extended temperature range (-40C to +125C). For all new designs, Microchip recommends the PIC18F45Q10 family with updated peripherals, but the K22 family remains a mature, fully-supported choice with extensive MPLAB X ecosystem tools.

Comparison with Alternatives

Parameter This Product PIC18F44K22-I/ML PIC18F44K22-E/ML PIC18F45K22-E/ML PIC18F45K20-I/ML
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package QFN-44 (8x8 mm) - ML QFN-44 (8x8 mm) - same QFN-44 (8x8 mm) - same QFN-44 (8x8 mm) - same QFN-44 (8x8 mm) - same
Flash Memory 32 KB 16 KB (-50%) 16 KB (-50%) 32 KB (same) 32 KB (same)
RAM 1536 B 1536 B (same) 1536 B (same) 1536 B (same) 1536 B (same)
Maximum CPU Speed 64 MHz (16 MIPS) 64 MHz (16 MIPS) - same 64 MHz (16 MIPS) - same 64 MHz (16 MIPS) - same 64 MHz (16 MIPS) - same
I/O Pins 36 36 - same 36 - same 36 - same 36 - same
Temperature Grade Industrial -40C to +85C Industrial -40C to +85C Extended -40C to +125C Extended -40C to +125C Industrial -40C to +85C
CTMU Capacitive Touch Yes (28 channels) Yes (28 channels) - same Yes (28 channels) - same Yes (28 channels) - same No
Lifecycle Status Active (newer PIC18F45Q10 recommended) Active Active Active Active

Key Differentiators

  • Larger Flash memory in same package (vs PIC18F44K22-I/ML)
  • CTMU capacitive touch support (vs PIC18F45K20-I/ML)
  • Industrial temperature grade option (vs PIC18F45K22-E/ML)

Design Notes

The PIC18F45K22-I/ML supports nanoWatt XLP modes including Sleep, Idle, and a low-power Sleep mode with sub-100 nA typical current. For battery-powered designs, configure unused peripherals to off state in firmware, disable the ADC when not in use (set ADCON1.ADON=0), and use the on-chip 64 MHz internal oscillator with PLL disabled if 16 MHz operation suffices. Estimated: at 3.3V VDD and 16 MHz CPU, active current is ~5 mA typical; sleep current is <100 nA typical per datasheet DC characteristics.

QFN-44 package layout requires attention to thermal dissipation and electrical grounding. The exposed pad (EP) at the bottom must be soldered to a continuous PCB ground pad, with at least 8 thermal vias (0.3 mm drill, 1.0 mm pitch) connecting to an internal ground plane. Place 100 nF decoupling capacitors as close as possible to each VDD pin (pins 20, 30, 44) and a 10 uF bulk capacitor near the VDD entry point. Avoid routing high-speed digital signals (PWM, EUSART, SPI) under the QFN-44 footprint to minimize crosstalk into the analog ADC inputs.

Common pitfalls when designing with PIC18F45K22-I/ML include: (1) forgetting the MCLR pull-up resistor (10 kohm typical to VDD), (2) leaving the WDT enabled unintentionally causing unwanted resets, (3) not configuring the configuration bits to match the application requirements (e.g., oscillator selection, BOR threshold, code protection), and (4) exceeding the 12-bit ADC input range when using internal voltage reference CVREF. Per datasheet: ensure configuration bits are programmed via MPLAB X before first code execution; an unconfigured part runs with default factory settings that may not match your design.

The PIC18F45K22-I/ML in QFN-44 package has a thermal resistance (theta_JA) of approximately 30 C/W on a standard 4-layer JEDEC test PCB. Estimated: at full 64 MHz operation with all peripherals active, internal power dissipation is below 100 mW, leading to <3 C junction temperature rise above ambient. The QFN exposed pad is the primary thermal path; ensure adequate PCB copper pour under the package. No external heatsink is required for typical embedded applications, but sustained high-current I/O drive (>20 mA per pin) should be distributed across multiple pins to avoid localized die heating.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant and lead-free per Microchip product page. Not AEC-Q100 qualified - the -I grade is industrial (non-automotive). For automotive applications, use AEC-Q100 qualified variants or contact Microchip for new automotive-grade part numbers.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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