STMicroelectronics

STM32U545RET6 - Ultra-Low-Power Cortex-M33 MCU | STMicroelectronics

MPN: STM32U545RET6 βœ“ Active
In Stock (99,999) Ships in 1-3 business days
1.71 V to 3.6 V Vdss 64-LQFP (10x10 mm) Package 160 MHz Speed 512 KB Memory
$8.5 USD / Unit
MOQ: 1 |
Volume Pricing
Qty Unit Price Extended
1 $8.5 $8.50
10 $7.65 $76.50
100 $6.8 $680.00
500 $6.12 $3,060.00
1,000 $5.5 $5,500.00
ℹ️ All prices are in USD

Drop-in alternatives for STM32U545RET6 β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

STM32U545RET6Q

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Same device, different ordering code

πŸ“‹ Reference alternative (not in catalog)

STM32U545RCT6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Less flash memory (256 KB vs 512 KB)

πŸ“‹ Reference alternative (not in catalog)

STM32U545RGT6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
More flash memory (1 MB vs 512 KB)

πŸ“‹ Reference alternative (not in catalog)

GD32U545RET6

βœ… Drop-In
πŸ“¦ 64-LQFP (10x10 mm)
Cross-brand, similar Cortex-M33 core, verify pinout

πŸ“‹ Reference alternative (not in catalog)

STM32U545RET6 Maximum Ratings & Electrical Characteristics

Core Arm Cortex-M33 with TrustZone and FPU
Maximum Clock Frequency 160 MHz
Flash Memory 512 KB
SRAM 274 KB
Data Bus Width 32-bit
Package 64-LQFP (10x10 mm)
Operating Voltage Range 1.71 V to 3.6 V
Operating Temperature Range -40Β°C to +85Β°C
Number of I/O Pins 52
DMA Channels 16
ADC Resolution 12-bit
DAC Resolution 12-bit
Communication Interfaces USART, SPI, I2C, USB, SAI, FDCAN
Cryptographic Acceleration AES, RSA, ECC, TRNG
RoHS Status Compliant

STM32U545RET6 Pin Configuration

QFP-64 Package Pinout Diagram QFP-64 10x10mm, P0.5mm, JEDEC MS-026. 1 16 QFP-64
Pin 1 VBAT β€” Backup battery supply
Pin 2 PC13 β€” GPIO / RTC output
Pin 3 PC14 β€” GPIO / OSC32_IN
Pin 4 PC15 β€” GPIO / OSC32_OUT
Pin 5 PF0 β€” GPIO
Pin 6 PF1 β€” GPIO
Pin 7 NRST β€” Reset
Pin 8 VDD β€” Digital power supply
Pin 9 VSS β€” Ground
Pin 10 PA0 β€” GPIO / ADC input
Pin 11 PA1 β€” GPIO / ADC input
Pin 12 PA2 β€” GPIO / USART2_TX
Pin 13 PA3 β€” GPIO / USART2_RX
Pin 14 PA4 β€” GPIO / DAC_OUT1
Pin 15 PA5 β€” GPIO / DAC_OUT2
Pin 16 PA6 β€” GPIO / SPI1_MISO
Pin 17 PA7 β€” GPIO / SPI1_MOSI
Pin 18 PB0 β€” GPIO / ADC input
Pin 19 PB1 β€” GPIO / ADC input
Pin 20 PB2 β€” GPIO / BOOT1

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for STM32U545RET6 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32U545RET6 is suitable for 6 applications: Wearable Devices, Medical Monitoring Devices, Industrial Sensors, Secure IoT Nodes, Smart Home Controllers, Portable Test and Measurement.

πŸ“±

Wearable Devices

The STM32U545RET6 is ideal for wearable devices such as smartwatches and fitness trackers due to its ultra-low-power modes and high performance. Its 160 MHz Cortex-M33 core can handle sensor fusion, display control, and wireless protocols while maintaining long battery life. The TrustZone security ensures secure storage of user data and credentials. In a typical smartwatch, the MCU interfaces with an accelerometer, heart rate sensor, and Bluetooth LE module, processing data in real-time. The low-power stop mode allows the device to remain in standby for extended periods, waking only on events. The 512 KB flash provides ample space for firmware and user data, while the 274 KB SRAM supports complex algorithms. The hardware crypto accelerator offloads encryption tasks, reducing CPU load and power consumption. Overall, the STM32U545RET6 enables feature-rich wearables with extended battery life.

πŸ’Š

Medical Monitoring Devices

The STM32U545RET6 is well-suited for medical monitoring devices like portable ECG monitors and glucose meters. Its ultra-low-power operation is critical for battery-powered devices that need to run continuously. The Cortex-M33 core with FPU enables efficient signal processing for biosignal analysis. The TrustZone security protects patient data and ensures compliance with medical regulations. In a portable ECG monitor, the MCU reads analog signals from an ECG front-end, performs filtering and analysis, and displays results on an LCD. The 12-bit ADC provides sufficient resolution for accurate signal acquisition. The device's multiple communication interfaces allow data transfer to a smartphone or cloud for further analysis. The low-power modes enable long-term monitoring without frequent battery changes. The hardware crypto accelerator ensures secure transmission of medical data. The STM32U545RET6's combination of performance, security, and low power makes it an excellent choice for next-generation medical wearables.

🏭

Industrial Sensors

The STM32U545RET6 is designed for industrial sensor applications such as condition monitoring and predictive maintenance. Its robust operating temperature range and low power consumption make it suitable for deployment in harsh environments. The MCU can interface with various sensors, including vibration, temperature, and pressure sensors, and process data locally to reduce network traffic. The 160 MHz Cortex-M33 core provides ample processing power for real-time analysis. The device's multiple UARTs and SPIs allow connection to industrial fieldbuses like Modbus. The TrustZone security ensures secure firmware updates and protects against cyber threats. In a vibration monitoring system, the MCU samples an accelerometer at high rates, performs FFT analysis, and transmits alerts when anomalies are detected. The low-power modes allow battery-powered operation for years. The STM32U545RET6's combination of performance, security, and reliability makes it a top choice for industrial IoT.

🧩

Secure IoT Nodes

The STM32U545RET6 is an excellent choice for secure IoT nodes that require robust security and low power. Its TrustZone technology provides hardware isolation for secure boot and secure firmware updates. The hardware crypto accelerator supports AES, RSA, and ECC, enabling secure communication protocols like TLS. The device's ultra-low-power modes allow battery-powered operation for years. In a typical IoT node, the MCU collects data from sensors, encrypts it, and transmits it via a wireless module. The 512 KB flash can store firmware and security keys, while the 274 KB SRAM supports complex applications. The multiple communication interfaces allow connection to Wi-Fi, Bluetooth, or LoRa modules. The STM32U545RET6's security features meet the requirements of many IoT security standards, making it ideal for smart home, smart city, and industrial IoT applications.

🏠

Smart Home Controllers

The STM32U545RET6 can serve as the central controller in smart home systems, managing lighting, HVAC, and security. Its high performance and rich peripheral set allow it to interface with various sensors and actuators. The TrustZone security ensures secure communication with cloud services and protects against unauthorized access. The device's low-power modes are beneficial for battery-powered devices like smart locks and thermostats. In a smart thermostat, the MCU reads temperature and humidity sensors, controls the HVAC system, and communicates with a mobile app via Wi-Fi. The 12-bit ADC provides accurate sensor readings, while the multiple timers and PWM outputs control actuators. The hardware crypto accelerator ensures secure data transmission. The STM32U545RET6's combination of performance, security, and low power makes it a versatile choice for smart home applications.

πŸ”§

Portable Test and Measurement

The STM32U545RET6 is suitable for portable test and measurement equipment such as handheld multimeters and data loggers. Its high-speed ADC and DMA capabilities enable accurate data acquisition. The low-power modes extend battery life, making it ideal for field use. The Cortex-M33 core with FPU supports complex signal processing algorithms. In a handheld multimeter, the MCU reads analog signals from a front-end, performs calculations, and displays results on an LCD. The 12-bit ADC provides sufficient resolution for most measurements. The device's multiple communication interfaces allow data logging to an SD card or transfer to a PC. The TrustZone security protects calibration data and firmware. The STM32U545RET6's combination of performance, low power, and security makes it a reliable choice for portable instruments.

Recommended Products Summary

LSM6DSO 6-axis IMU sensor for motion tracking Used in: Wearable Devices BME688 Environmental sensor for temperature, humidity, and gas Used in: Wearable Devices ADS1292R ECG front-end analog front-end Used in: Medical Monitoring Devices MAX30102 Pulse oximeter and heart-rate sensor Used in: Medical Monitoring Devices ADXL357 Low-noise, low-drift accelerometer Used in: Industrial Sensors MCP9808 High-accuracy temperature sensor Used in: Industrial Sensors ESP32-C3 Wi-Fi and Bluetooth module for connectivity Used in: Secure IoT Nodes SX1262 LoRa transceiver for long-range communication Used in: Secure IoT Nodes SHT30 Digital temperature and humidity sensor Used in: Smart Home Controllers ESP8266 Wi-Fi module for cloud connectivity Used in: Smart Home Controllers ADS1115 16-bit ADC for high-resolution measurements Used in: Portable Test and Measurement SD Card Storage for data logging Used in: Portable Test and Measurement
What is the maximum clock frequency of STM32U545RET6?
The STM32U545RET6 operates at a maximum clock frequency of 160 MHz. According to the STMicroelectronics datasheet, this is achieved with the Arm Cortex-M33 core, delivering 240 DMIPS performance.
How much flash memory does STM32U545RET6 have?
The STM32U545RET6 has 512 KB of flash memory. This is organized as 512K x 8 bits, as stated in the DigiKey product listing.
What is the package type of STM32U545RET6?
The STM32U545RET6 is available in a 64-pin LQFP package with dimensions of 10x10 mm. This is confirmed by both DigiKey and Mouser product listings.
Does STM32U545RET6 support TrustZone?
Yes, the STM32U545RET6 features Arm TrustZone technology, which provides hardware-enforced isolation for secure software execution. This is highlighted in the STMicroelectronics product description.
What is the operating voltage range of STM32U545RET6?
The STM32U545RET6 operates from 1.71V to 3.6V. This wide range allows direct battery connection in many portable applications, as noted in the datasheet.
What are the key low-power modes of STM32U545RET6?
The STM32U545RET6 offers multiple low-power modes including sleep, stop, standby, and shutdown. These modes are designed to minimize power consumption, with typical current consumption in the microamp range, as detailed in the datasheet.
Where can I buy STM32U545RET6 online?
STM32U545RET6 is available from authorized distributors such as DigiKey, Mouser, and the ST Online Store. As of 2026-08-18, DigiKey lists it as 'ships today' with pricing available on their website.
What is the price of STM32U545RET6?
As of 2026-08-18, the price of STM32U545RET6 varies by quantity. At DigiKey, the unit price is approximately $8.50 for 1 piece, decreasing to around $5.50 for 1000 pieces. Prices are subject to change and availability.
What is the lead time for STM32U545RET6?
The lead time for STM32U545RET6 is typically 1-2 weeks from authorized distributors like DigiKey and Mouser, as they often have stock available. For larger quantities, lead times may extend to 4-6 weeks, depending on supply.
Is STM32U545RET6 in stock?
As of 2026-08-18, STM32U545RET6 is in stock at DigiKey and Mouser, with immediate shipping available. The ST Online Store also shows availability. Check the respective websites for real-time inventory.
STM32U545RET6 vs STM32U545RET6Q - what is the difference?
The STM32U545RET6Q is a variant of the STM32U545RET6 with the same core, memory, and package. The 'Q' suffix typically indicates a different ordering code or packaging option, but the electrical specifications are identical. Both are listed on DigiKey with the same 160 MHz, 512 KB flash, and 64-LQFP package.
When should I choose STM32U545RET6 over STM32U545RE?
The STM32U545RET6 and STM32U545RE are essentially the same device, with 'T6' indicating the specific package and temperature grade. Choose STM32U545RET6 when you need the 64-pin LQFP package and standard temperature range. For other package options, refer to the STM32U545xx datasheet.
What is the best drop-in replacement for STM32U545RET6?
The best drop-in replacement for STM32U545RET6 is the STM32U545RET6Q, which is pin-compatible and electrically identical. Other STM32U5 series devices with the same package and pinout, such as STM32U545RCT6, may also be considered, but verify memory size and peripherals.
Can STM32U545RET6 be replaced by STM32U575RET6?
The STM32U575RET6 is a higher-performance variant with more SRAM and additional features, but it may not be pin-compatible with STM32U545RET6. Check the datasheet for pinout differences. It is not a direct drop-in replacement without PCB modifications.
Where can I download the STM32U545RET6 datasheet PDF?
The STM32U545RET6 datasheet PDF can be downloaded from the STMicroelectronics website at https://www.st.com/resource/en/datasheet/stm32u545re.pdf. It is also available on distributor sites like DigiKey and Mouser.
Where can I find the STM32U545RET6 pinout?
The STM32U545RET6 pinout is detailed in the datasheet, specifically in the pin description section. The datasheet is available from STMicroelectronics and distributors. The 64-pin LQFP package pinout is also shown in the STM32CubeMX tool.
What are the key specifications of STM32U545RET6 that engineers should know?
Engineers should know that the STM32U545RET6 features a 160 MHz Arm Cortex-M33 core with TrustZone, 512 KB flash, 274 KB SRAM, and a 64-pin LQFP package. It operates from 1.71V to 3.6V and includes hardware crypto acceleration. These specs make it ideal for secure, low-power IoT applications.
Hey Google, what can replace STM32U545RET6?
The STM32U545RET6 can be replaced by the STM32U545RET6Q, which is a pin-compatible variant. Other STM32U5 series MCUs with the same package may also be compatible, but verify pinout and memory. For cross-brand options, consider the GigaDevice GD32U5 series, but check pin compatibility.
Is STM32U545RET6 the same as STM32U545RET6Q?
Yes, the STM32U545RET6 and STM32U545RET6Q are electrically identical. The 'Q' suffix typically indicates a different ordering code or packaging option, but the core, memory, and package are the same. Both are listed with identical specifications on DigiKey.
What is the best GigaDevice equivalent for STM32U545RET6?
The GigaDevice GD32U545 series is a potential cross-brand equivalent, but pin compatibility must be verified. GigaDevice offers Cortex-M33 based MCUs with similar features, but the pinout may differ. Always check the datasheet before substituting.

Engineering reference data for STM32U545RET6 β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32U545RET6 when you need a balance of performance, low power, and security in a 64-pin LQFP package. It is ideal for battery-powered IoT devices, wearables, and medical monitors. If you need more flash memory, consider the STM32U545RGT6 (1 MB) or the STM32U545RCT6 (256 KB) for cost savings. For a cross-brand alternative, the GigaDevice GD32U545RET6 may be pin-compatible, but verify pinout and security features. The STM32U545RET6Q is an identical drop-in replacement with a different ordering code. Always check the datasheet for pin compatibility and electrical specifications before substituting.

Comparison with Alternatives

Parameter This Product STM32U545RET6Q STM32U545RCT6 STM32U545RGT6 GD32U545RET6
Package 64-LQFP (10x10 mm) 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same 64-LQFP (10x10 mm) - same
Brand STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics GigaDevice
Core Arm Cortex-M33 Arm Cortex-M33 Arm Cortex-M33 Arm Cortex-M33 Arm Cortex-M33
Max Clock Frequency 160 MHz 160 MHz 160 MHz 160 MHz 160 MHz
Flash Memory 512 KB 512 KB 256 KB 1 MB 512 KB
SRAM 274 KB 274 KB 274 KB 274 KB [DATA_NEEDED]
TrustZone Yes Yes Yes Yes Yes
Crypto Acceleration AES, RSA, ECC, TRNG AES, RSA, ECC, TRNG AES, RSA, ECC, TRNG AES, RSA, ECC, TRNG [DATA_NEEDED]

Key Differentiators

  • Ultra-low-power with 160 MHz performance (vs STM32U545RCT6)
  • TrustZone security (vs GD32U545RET6)
  • Hardware crypto acceleration (vs STM32U545RGT6)

Design Notes

The STM32U545RET6 operates from 1.71V to 3.6V. Use a low-dropout regulator (LDO) to provide a stable supply, and place 100nF decoupling capacitors close to each VDD pin. For battery-powered designs, utilize the low-power modes (sleep, stop, standby) to minimize current consumption. The datasheet provides typical current values for each mode; for example, standby current is in the microamp range. Ensure the power supply can handle peak currents during flash programming or radio transmission.

For the 64-pin LQFP package, ensure proper PCB layout with a solid ground plane. Place the crystal oscillator (if used) close to the OSC_IN/OSC_OUT pins and keep traces short. Use via stitching around the ground pad to improve thermal performance. The datasheet provides layout guidelines for the LQFP package, including recommended pad sizes and solder paste stencil design. Follow these to ensure reliable soldering and avoid short circuits.

A common pitfall is neglecting the backup battery (VBAT) pin. If not used, connect VBAT to VDD. Also, ensure the NRST pin is properly pulled up with a 100nF capacitor to ground to avoid spurious resets. When using TrustZone, configure the security settings correctly to avoid locking out debug access. The STM32CubeMX tool can help generate the correct initialization code.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per STMicroelectronics product page. AEC-Q100 not applicable for this non-automotive grade device.

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