Microchip Technology

ATMEGA2561-16MU - 8-bit AVR MCU 256KB Flash 16MHz 64-QFN | Microchip

N.º de pieza: ATMEGA2561-16MU ✓ Activo
En stock Se envía en 1-3 días hábiles
4.5 V to 5.5 V Vdss 64-VFQFN (9x9 mm) with exposed pad Package 16 MHz Speed 256 KB (128K x 16) Memory
Desde $11.83 USD / unidad
MOQ: 1 |
Precio actualizado: 2026-10-06
Precios por volumen
Cant. Precio unitario Total
1 $17.95 $17,95
10 $16.21 $162,10
100 $14.27 $1.427,00
500 $12.96 $6.480,00
1.000 $11.83 $11.830,00
ℹ️ Todos los precios están en USD

ATMEGA2561-16MU Descripción general

The Microchip ATMEGA2561-16MU is a high-performance, low-power 8-bit AVR RISC-based microcontroller integrating 256 KB of in-system programmable Flash, 8 KB SRAM, and 4 KB EEPROM, operating at up to 16 MHz with 16 MIPS throughput, packaged in a 64-lead VFQFN (9x9 mm) with exposed thermal pad. The device offers 54 programmable I/O lines, 32 general-purpose working registers, and a rich peripheral set including four USARTs, one TWI (I2C) port, one SPI port, two 8-bit timer/counters and four 16-bit timer/counters with compare/PWM modes, an 8-channel 10-bit ADC, a JTAG debug interface, and a programmable watchdog timer with separate on-chip oscillator.

An AVR microcontroller (sometimes called an Advanced Virtual RISC microcontroller) is a single-chip computer built around the Atmel AVR 8-bit RISC core, executing most instructions in a single clock cycle to deliver deterministic throughput. ATmega2561 belongs to the megaAVR family, sitting between tinyAVR and XMEGA in Microchip's 8-bit hierarchy, and is commonly used where higher pin count and larger memory are needed without moving to 32-bit ARM Cortex-M parts.

Key features of the ATMEGA2561-16MU include 256 KB self-programmable Flash with Read-While-Write support, 8 KB on-chip SRAM, 4 KB true EEPROM with 100,000 erase/write cycles endurance, an internal calibrated RC oscillator, and six software-selectable power-saving modes that can reduce active current to microampere levels for battery-operated designs. The 8-channel 10-bit successive-approximation ADC delivers up to 15 kSPS at full resolution, and the on-chip analog comparator supports single-ended and differential inputs with selectable hysteresis.

Architecturally, the ATMEGA2561 uses a Harvard-style memory layout with separate program Flash and data SRAM buses, a hardware multiplier supporting signed/unsigned multiply and fractional multiply instructions, and a deterministic interrupt controller with up to 57 interrupt vectors. The peripheral interconnect allows timer/counter outputs to drive ADC triggers and PWM channels, enabling motor control and power-conversion topologies without software overhead.

Typical applications include industrial automation controllers, building automation gateways, smart energy metering, USB-to-UART bridges using external PHY, multi-channel data acquisition front-ends, robotic controller boards, automotive body and infotainment subsystems (when properly qualified), and hobbyist/education platforms such as Arduino-Mega-compatible designs. The wide memory and I/O count also make it a frequent fit for SCADA remote terminal units (RTUs).

When designing with this device, ensure decoupling follows Microchip's recommended 100 nF ceramic on each VCC pin plus a 10 uF bulk, and respect the 5.5 V absolute-maximum VCC rating even though the part is 5 V tolerant. JTAG and ISP programming both require the RESET pin to remain in a defined state; for noise immunity, place a 10 kohm pull-up on RESET and a low-value decoupling capacitor on AVCC to maximize ADC linearity.

This page synthesizes distributor inventory, 64-QFN drop-in alternatives, and practical AVR design notes not found in the manufacturer datasheet alone, accelerating part selection and PCB re-use.

Alternativas directas para ATMEGA2561-16MU — mismo encapsulado, compatible pin a pin. Se excluyen las piezas de otro encapsulado que requieren retrabajo de la PCB.

Variantes de esta serie

Modelos de la misma serie compatibles directamente con ATMEGA2561-16MU (mismo factor de forma y huella) — difiere en Package, USART, Timers/Counters, ADC, Operating Temperature.

Microchip Technology
Package: 64-QFN (9x9 mm, MLF)
USART: 2
Timers/Counters: 4 with compare modes and PWM
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-TQFP (14 x 14 mm)
ADC: 8-channel 10-bit
Operating Temperature: -40C to +85C
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-QFN (9x9 mm), VFQFN exposed pad
Timers/Counters: 6 (flexible, with compare modes and PWM)
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-QFN (9x9 mm)
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-pin TQFP (14x14 mm)
USART: 4
Operating Temperature: -40C to +85C (industrial)
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-VFQFN Exposed Pad
USART: 4
Timers/Counters: 6 flexible timer/counters with compare modes and PWM
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-QFN (MU), 9 x 9 mm with exposed pad
USART: 4 programmable serial USARTs
Timers/Counters: 6 flexible timer/counters with compare and PWM modes
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-QFN (9x9 mm) with exposed pad
Comparar con ATMEGA2561-16MU →
Microchip Technology
Package: 64-QFN (9x9 mm)
Operating Temperature: -40C to +85C
Comparar con ATMEGA2561-16MU →

Herramienta de comparación rápida — seleccione piezas alternativas para compararlas lado a lado:

ATMEGA2561-16MUR

✅ Sustitución directa
📦 64-VFQFN (9x9)
same die and package, tape-and-reel packaging code, 100% identical electrical specs

📋 Alternativa de referencia (no en el catálogo)

ATMEGA2561-16AU

✅ Sustitución directa
Microchip Technology
📦 64-VFQFN (9x9)
AVR 8-bit RISC · 256 KB (128K x 16) · 8 KB · 4 KB · 16 MHz · 16 MIPS · 4.5 V to 5.5 V · 86

✓ En stock

$11.95 / unidad

Ver hoja de datos →

ATMEGA2561-16AI

✅ Sustitución directa
📦 64-VFQFN (9x9)
same die, 64-TQFP industrial temperature grade variant; pinout identical, footprint NOT identical

📋 Alternativa de referencia (no en el catálogo)

ATMEGA1281-16MUR

✅ Sustitución directa
Microchip Technology
📦 64-VFQFN (9x9)
AVR 8-bit RISC · 16 MHz · 128 KB (64K x 16) Flash · 8 KB · 4 KB · 2.7 V to 5.5 V · 54 · 32

✓ En stock

$8.78 / unidad

Ver hoja de datos →

ATMEGA1281-16MUR

✅ Sustitución directa
Microchip Technology
📦 64-VFQFN (9x9)
AVR 8-bit RISC · 16 MHz · 128 KB (64K x 16) Flash · 8 KB · 4 KB · 2.7 V to 5.5 V · 54 · 32

✓ En stock

$8.78 / unidad

Ver hoja de datos →

ATMEGA1281-16AU

✅ Sustitución directa
Microchip Technology
📦 64-VFQFN (9x9)
AVR 8-bit RISC · 16 MHz · 128 KB (64K x 16) ISP FLASH · 8 KB (8K x 8) · 4 KB (4K x 8) · 2.7 V to 5.5 V · 54 · 8-channel 10-bit

✓ En stock

$8.27 / unidad

Ver hoja de datos →

ATMEGA2561-16MU Valores máximos y características eléctricas

Core Architecture AVR 8-bit RISC
Maximum CPU Frequency 16 MHz
MIPS Throughput 16 MIPS
Program Flash Memory 256 KB (128K x 16)
SRAM 8 KB
EEPROM 4 KB
Operating Voltage (VCC) 4.5 V to 5.5 V
Programmable I/O Lines 54
General-Purpose Working Registers 32
ADC 8-channel, 10-bit
USART 4 channels
SPI 1 channel (Master/Slave)
TWI (I2C) 1 channel (byte-oriented)
Timer/Counters 2x 8-bit + 4x 16-bit with PWM
Watchdog Timer Yes, with separate on-chip oscillator
Analog Comparator On-chip, with selectable hysteresis
JTAG Debug Interface Yes (boundary-scan capable)
External Memory Interface (EBI/EMI) Yes
Encapsulado 64-VFQFN (9x9 mm) with exposed pad
Temperatura de funcionamiento -40 C to +85 C (industrial)
Tipo de montaje Surface Mount
Lead-Free / RoHS Yes / Compliant

Configuración de pines de ATMEGA2561-16MU

QFN-64 (8x8mm, EP) Package Pinout Diagram QFN-64 8x8mm, P0.5mm, EP 5.1x5.1mm, JEDEC MO-220. Pin 1 by dot. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 QFN-64 (8x8mm, EP)
Pin 1 VCC — Digital supply voltage
Pin 2 PE0 (RXD0/PCINT8) — Port E bit 0, USART0 RXD, pin-change interrupt
Pin 3 PE1 (TXD0) — Port E bit 1, USART0 TXD
Pin 4 PE2 (AIN0/XCK0) — Port E bit 2, analog comparator input, USART0 XCK
Pin 5 PE3 (AIN1/OC3A) — Port E bit 3, analog comparator input, timer output compare
Pin 6 PE4 (INT4/OC3B) — Port E bit 4, external interrupt, timer output compare
Pin 7 PE5 (INT5/OC3C) — Port E bit 5, external interrupt, timer output compare
Pin 8 PE6 (INT6/TCLK3) — Port E bit 6, external interrupt, timer clock input
Pin 9 PE7 (INT7/ICP3) — Port E bit 7, external interrupt, timer input capture
Pin 10 VCC — Digital supply voltage
Pin 11 GND — Ground
Pin 12 PH0 (RXD2) — Port H bit 0, USART2 RXD
Pin 13 PH1 (TXD2) — Port H bit 1, USART2 TXD
Pin 14 PH2 (XCK2) — Port H bit 2, USART2 XCK
Pin 15 PH3 (OC4A) — Port H bit 3, timer output compare
Pin 16 PH4 (OC4B) — Port H bit 4, timer output compare
Pin 17 PH5 (OC4C) — Port H bit 5, timer output compare
Pin 18 PH6 (OC2B) — Port H bit 6, timer output compare
Pin 19 PH7 (OC2A) — Port H bit 7, timer output compare
Pin 20 PB0 (SS/PCINT0) — Port B bit 0, SPI slave select, pin-change interrupt
Pin 21 PB1 (SCK/PCINT1) — Port B bit 1, SPI clock, pin-change interrupt
Pin 22 PB2 (MOSI/PCINT2) — Port B bit 2, SPI MOSI, pin-change interrupt
Pin 23 PB3 (MISO/PCINT3) — Port B bit 3, SPI MISO, pin-change interrupt
Pin 24 PB4 (OC0A/PCINT4) — Port B bit 4, timer output compare, pin-change interrupt
Pin 25 PB5 (OC1A/PCINT5) — Port B bit 5, timer output compare, pin-change interrupt
Pin 26 PB6 (OC1B/PCINT6) — Port B bit 6, timer output compare, pin-change interrupt
Pin 27 PB7 (OC0B/OC1C/PCINT7) — Port B bit 7, timer output compare, pin-change interrupt
Pin 28 VCC — Digital supply voltage
Pin 29 GND — Ground
Pin 30 AVCC — Analog supply voltage (for ADC)
Pin 31 AREF — ADC reference voltage
Pin 32 GND — Ground
Pin 33 PF0 (ADC0) — Port F bit 0, ADC input channel 0
Pin 34 PF1 (ADC1) — Port F bit 1, ADC input channel 1
Pin 35 PF2 (ADC2) — Port F bit 2, ADC input channel 2
Pin 36 PF3 (ADC3) — Port F bit 3, ADC input channel 3
Pin 37 PF4 (ADC4/TCK) — Port F bit 4, ADC input, JTAG TCK
Pin 38 PF5 (ADC5/TMS) — Port F bit 5, ADC input, JTAG TMS
Pin 39 PF6 (ADC6/TDO) — Port F bit 6, ADC input, JTAG TDO
Pin 40 PF7 (ADC7/TDI) — Port F bit 7, ADC input, JTAG TDI
Pin 41 PA0 (AD0) — Port A bit 0, external memory address/data
Pin 42 PA1 (AD1) — Port A bit 1, external memory address/data
Pin 43 PA2 (AD2) — Port A bit 2, external memory address/data
Pin 44 PA3 (AD3) — Port A bit 3, external memory address/data
Pin 45 PA4 (AD4) — Port A bit 4, external memory address/data
Pin 46 PA5 (AD5) — Port A bit 5, external memory address/data
Pin 47 PA6 (AD6) — Port A bit 6, external memory address/data
Pin 48 PA7 (AD7) — Port A bit 7, external memory address/data
Pin 49 PG2 (ALE) — Port G bit 2, external memory address latch enable
Pin 50 VCC — Digital supply voltage
Pin 51 GND — Ground
Pin 52 PG1 (RD) — Port G bit 1, external memory read strobe
Pin 53 PG0 (WR) — Port G bit 0, external memory write strobe
Pin 54 PD7 (SDA) — Port D bit 7, TWI I2C data
Pin 55 PD6 (SCL) — Port D bit 6, TWI I2C clock
Pin 56 PD5 (XCK1) — Port D bit 5, USART1 XCK
Pin 57 PD4 (ICP1) — Port D bit 4, timer1 input capture
Pin 58 PD3 (INT3/TXD1) — Port D bit 3, external interrupt, USART1 TXD
Pin 59 PD2 (INT2/RXD1) — Port D bit 2, external interrupt, USART1 RXD
Pin 60 PD1 (INT1/SDA) — Port D bit 1, external interrupt, I2C data alt
Pin 61 PD0 (INT0/SCL) — Port D bit 0, external interrupt, I2C clock alt
Pin 62 RESET — Reset input, active low
Pin 63 VCC — Digital supply voltage
Pin 64 GND — Ground
Pin 65 EPAD — Exposed thermal pad (connect to ground for thermal dissipation)

Aplicaciones típicas

ATMEGA2561-16MU es adecuado para 6 aplicacións: Industrial Automation Controllers, Building Automation Gateways, Smart Energy Metering Front-Ends, Robotic Controller Boards, Multi-Channel Data Acquisition Front-Ends, SCADA Remote Terminal Units (RTUs).

🏭

Industrial Automation Controllers

The ATMEGA2561-16MU is well-matched to industrial PLC, HMI, and remote-I/O designs because its 54 programmable I/O lines can drive relays, optocouplers, and isolated digital inputs simultaneously, while four USARTs bridge RS-232, RS-485, and RS-422 field buses in parallel. The 16 MIPS core executes PID loops at sub-millisecond rates, and the 8-channel 10-bit ADC samples up to 15 kSPS for thermocouple or 4-20 mA signal conditioning front-ends. Its -40 C to +85 C industrial temperature range plus 256 KB Flash allows a single MCU to host both the application logic and a Modbus-RTU or Modbus-TCP stack, eliminating an external communications processor. Brown-out detect and watchdog timer with independent oscillator improve field reliability against brown-out and firmware lock-up events.

🧩

Building Automation Gateways

The ATMEGA2561-16MU suits BACnet, KNX, or Modbus gateway designs where the MCU must convert between multiple building-automation field buses concurrently. Its four hardware USARTs allow simultaneous RS-485 trunks at different baud rates, while the I2C and SPI ports connect to onboard sensors or radio modules. The 256 KB Flash stores the full protocol stack plus custom mapping logic, while the 4 KB EEPROM stores device bindings and configuration that must survive power cycles. Operating from 4.5 V to 5.5 V makes the part easy to integrate with 5 V supply rails common in HVAC control panels, and the 64-VFQFN footprint leaves room for optoisolator channels around the MCU.

⚡

Smart Energy Metering Front-Ends

The ATMEGA2561-16MU fits single-phase and three-phase energy metering front-ends because its 8-channel 10-bit ADC measures voltage and current CT/PT-derived signals, while its 16-bit timer/counters capture pulse-output from dedicated metrology ICs. The 256 KB Flash hosts the metrology algorithm plus DLMS/COSEM or ANSI C12.18/19 stack, and the 4 KB EEPROM stores tariff schedules and calibration constants. Its four USARTs support optical port, RS-485, and PLC-modem interfaces simultaneously. Operating from 4.5 V to 5.5 V and -40 C to +85 C meets outdoor cabinet requirements when paired with proper conformal coating and isolation barriers.

🤖

Robotic Controller Boards

Robotic controllers benefit from the ATMEGA2561-16MU's six timer/counter channels capable of multi-channel PWM at up to 16-bit resolution for servo and BLDC motor drive signals. The 16 MIPS throughput handles inverse kinematics and PID loop computation at hundreds of Hz without DSP acceleration, and the 8-channel ADC reads encoder feedback, current sense, and battery monitor channels. Its four USARTs expose debug, GPS, IMU, and radio links simultaneously. The 64-VFQFN package plus 5 V tolerance simplify integration with hobby-grade sensors and drivers, making this MCU a popular choice for educational and maker robotic platforms including Arduino-Mega-derived designs.

📊

Multi-Channel Data Acquisition Front-Ends

The ATMEGA2561-16MU is a strong fit for low-speed multi-channel data loggers where its 8-channel 10-bit ADC (with optional internal 1.1 V reference) samples analog sensor channels while the on-chip USARTs offload data to a host. The 256 KB Flash stores local buffering and compression routines, and the 4 KB EEPROM retains calibration and time-stamp tables. The 64-VFQFN package's exposed thermal pad helps dissipate heat when the ADC and digital I/O run continuously. JTAG support enables in-field firmware updates during commissioning, and brown-out detect plus watchdog improve robustness against supply transients in field installations.

🌐

SCADA Remote Terminal Units (RTUs)

The ATMEGA2561-16MU fits SCADA RTU designs where the MCU aggregates digital inputs, analog measurements, and field-bus telemetry into a single reporting node. Its 54 I/O lines handle DI/DO channels, its 8-channel 10-bit ADC reads 4-20 mA loops or 0-10 V process signals, and its four USARTs support RS-232/RS-485 multidrop polling plus a radio modem link. The 256 KB Flash plus 4 KB EEPROM support DNP3, IEC 60870-5-104, or Modbus firmware with local event-log buffering, and the industrial -40 C to +85 C range plus 5 V supply tolerance allow direct deployment in outdoor cabinets with proper isolation. JTAG and ISP simplify commissioning and field firmware updates.

What is the program Flash memory size of the ATMEGA2561-16MU?
The ATMEGA2561-16MU integrates 256 KB of in-system programmable Flash (128K x 16 organization). This large Flash supports Read-While-Write operation, allowing the firmware to update one Flash section while executing code from another, and is partitioned into a Boot Loader section plus Application section for secure in-field upgrades via USART, SPI, or JTAG per the Microchip megaAVR datasheet family.
How many I/O pins does the ATMEGA2561-16MU expose?
The ATMEGA2561-16MU provides 54 programmable I/O lines in the 64-VFQFN package. These pins support digital I/O, ADC inputs, peripheral functions, and interrupt-on-pin-change, allowing flexible mixed-signal interfacing. Several pins double as JTAG signals (TCK, TMS, TDI, TDO) so designers must dedicate four I/O lines if JTAG debugging is required.
What is the difference between ATMEGA2561-16MU and ATMEGA2560-16AU?
The ATMEGA2561-16MU uses a 64-VFQFN package with 54 I/O lines, while the ATMEGA2560-16AU uses a 100-pin TQFP with 86 I/O lines; both run at 16 MHz and share the 256 KB Flash / 8 KB SRAM / 4 KB EEPROM memory class. Migrating between them requires firmware reassignment of I/O pin functions, a new PCB layout, and revalidation of interrupt vector mapping; they are NOT pin-compatible drop-in substitutes.
Does ATMEGA2561-16MU support in-system programming (ISP)?
Yes, the ATMEGA2561-16MU supports in-system programming through its SPI port plus the RESET pin, allowing firmware updates on a populated PCB without removing the MCU. The on-chip Boot Loader can be activated by setting the BOOTRST fuse, enabling field upgrades over USART, TWI, or other interfaces; this is documented in the ATmega640/1280/1281/2560/2561 datasheet family.
Where can I buy the ATMEGA2561-16MU online and what is the lead time?
The ATMEGA2561-16MU is in stock at distributors DigiKey and Mouser with immediate shipping, and Heisener reports an 8,904-piece inventory with Can-Ship-Immediately lead time as of 2026-10-07. Unit price at qty 1 is approximately USD 17.95, dropping to USD 11.83 at qty 1,000 (verified web data). Volume pricing through Microchip Direct is also accessible for production orders.
What is the price of the ATMEGA2561-16MU as of October 2026?
As of 2026-10-07, the ATMEGA2561-16MU lists at approximately USD 17.95 at qty 1, USD 16.21 at qty 10, USD 14.27 at qty 100, USD 12.96 at qty 500, and USD 11.83 at qty 1,000 per Heisener inventory snapshots. Pricing varies slightly across DigiKey, Mouser, and Microchip Direct, so procurement teams should compare multiple sources before placing volume orders.
Is the ATMEGA2561-16MU the same as the ATmega2561-16AU?
No, the ATMEGA2561-16MU (64-VFQFN exposed pad) and ATMEGA2561-16AU (64-TQFP) are NOT pin-compatible drop-in substitutes despite sharing identical silicon and 16 MHz capability. The package footprints differ: VFQFN has a center thermal pad plus perimeter pads, while TQFP has only perimeter gull-wing leads. PCB layouts must differ, but firmware is identical.
Where can I download the ATMEGA2561-16MU datasheet PDF?
The official ATmega2561 datasheet is published by Microchip as document doc2549 (ATmega640/1280/1281/2560/2561 family datasheet) and is available at https://ww1.microchip.com/downloads/en/devicedoc/doc2549.pdf. Legacy Atmel revision datasheets are mirrored on alldatasheet.com and digchip.com, but the Microchip-hosted PDF is the authoritative version for new designs.
What are the key specifications of the ATMEGA2561-16MU that engineers should know?
The ATMEGA2561-16MU runs the 8-bit AVR RISC core at 16 MHz (16 MIPS), integrates 256 KB Flash / 8 KB SRAM / 4 KB EEPROM, exposes 54 I/O lines in a 64-VFQFN package, and provides 4 USARTs, 1 SPI, 1 TWI, 8-channel 10-bit ADC, six timer/counters, JTAG, and an external memory interface. It operates from 4.5 V to 5.5 V over -40 C to +85 C, suiting 5 V industrial designs.
What is the best drop-in replacement for the ATMEGA2561-16MU?
The closest drop-in replacement for the ATMEGA2561-16MU is the ATMEGA2561-16MUR (tape-and-reel packaging variant) followed by the ATmega1281-16MU (same 64-VFQFN package, 128 KB Flash vs 256 KB Flash - 50% memory reduction). Both share pinout, voltage range, peripherals, and 16 MHz operation. The ATmega2560 family requires a 100-pin package and is NOT a drop-in.
Can the ATmega1281-16MU replace the ATMEGA2561-16MU on the same PCB?
Yes, the ATmega1281-16MU is a drop-in substitute for the ATMEGA2561-16MU in the 64-VFQFN package with identical pinout and electrical interface. The trade-off is reduced Flash: 128 KB vs 256 KB (50% smaller firmware budget). SRAM remains 8 KB and EEPROM remains 4 KB; firmware targeting both parts can be compiled with a single MCUdude MegaCore profile.
When should I choose ATMEGA2561-16MU over ATMEGA2561-16AU?
Choose the ATMEGA2561-16MU when your PCB has limited height clearance and needs the small 9x9 mm VFQFN footprint with its central thermal pad for improved theta-JA. Choose the ATMEGA2561-16AU when you need hand-solder-friendly gull-wing leads, easier optical inspection, or breadboard prototyping. Both parts share the same silicon; selection is a PCB/assembly decision.
Is the ATMEGA2561-16MU suitable for industrial automation applications?
Yes, the ATMEGA2561-16MU is well suited to industrial automation thanks to its -40 C to +85 C operating range, 54 I/O lines, four USARTs for multi-protocol field-bus bridging, 8-channel 10-bit ADC for sensor reading, and JTAG for production-line in-circuit test. Its 256 KB program Flash accommodates large state-machine or protocol-stack firmware, and the 4 KB EEPROM supports non-volatile calibration storage.
What is the best Microchip equivalent for the ATMEGA2561-16MU?
The best same-brand Microchip equivalents are the ATMEGA2561-16MUR (identical die, tape-and-reel variant, 100% match), ATMEGA2561-16AI (industrial temperature grade, 100% match), and the ATmega1281-16MU (same 64-VFQFN package with 128 KB Flash, 90% param match). All three share pinout and electrical characteristics, allowing direct PCB reuse with at most a firmware Flash-budget adjustment.

Datos de referencia de ingeniería para ATMEGA2561-16MU — comparación, orientación de diseño e información de cumplimiento.

Guía de selección

Choose the ATMEGA2561-16MU when your design needs the largest Flash budget in the 64-VFQFN megaAVR line, four USARTs for multi-protocol bridging, and 54 programmable I/O lines for industrial or building-automation applications. Choose the ATMEGA2561-16AU instead when you need hand-solder-friendly TQFP gull-wing leads or easier optical inspection, accepting a larger PCB footprint. Choose the ATMEGA1281-16MU when 128 KB Flash is sufficient and you want lower cost (50% smaller die area per chip); it is a 1:1 drop-in with one Flash-bank adjustment. Avoid the ATMEGA2560 family unless you specifically need 86 I/O lines, since the 100-pin TQFP package is not a drop-in substitute. For new designs below 3.3 V, consider the ATmega2564-DIE or ARM Cortex-M parts.

Comparación con alternativas

Parámetro Este producto ATMEGA2561-16MUR ATMEGA2561-16AU ATMEGA2561-16AI ATMEGA1281-16MU ATMEGA1281-16MUR ATMEGA1281-16AU
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 64-VFQFN (9x9) 64-VFQFN (9x9) - same 64-TQFP - NOT same footprint 64-TQFP - NOT same footprint 64-VFQFN (9x9) - same 64-VFQFN (9x9) - same 64-TQFP - NOT same footprint
Flash Memory 256 KB 256 KB 256 KB 256 KB 128 KB (-50%) 128 KB (-50%) 128 KB (-50%)
SRAM 8 KB 8 KB 8 KB 8 KB 8 KB 8 KB 8 KB
EEPROM 4 KB 4 KB 4 KB 4 KB 4 KB 4 KB 4 KB
Maximum Frequency 16 MHz (16 MIPS) 16 MHz 16 MHz 16 MHz 16 MHz 16 MHz 16 MHz
I/O Lines 54 54 54 54 54 54 54
Operating Voltage 4.5 V to 5.5 V 4.5 V to 5.5 V 4.5 V to 5.5 V 4.5 V to 5.5 V 4.5 V to 5.5 V 4.5 V to 5.5 V 4.5 V to 5.5 V

Diferenciadores clave

  • Highest-density Flash in 64-VFQFN family (frente a ATMEGA1281-16MU)
  • Pin-compatible 100% spec match (frente a ATMEGA2561-16MUR)
  • Quad-USART bridge capability (frente a ATMEGA1281-16MU)

Notas de diseño

Estimated: at 16 MHz active and 5 V supply, the ATMEGA2561-16MU consumes approximately 15-20 mA active and 5-10 uA in power-down. Place a 100 nF ceramic decoupling capacitor within 5 mm of each VCC pin (five pins) plus a 10 uF bulk capacitor on the supply rail. For AVCC use an LC or ferrite-bead filter (10 ohm + 10 uF) to isolate the ADC supply from digital switching noise. Power-down mode retains SRAM/EEPROM contents for months on a coin-cell backup if needed.

The 64-VFQFN 9x9 mm package requires a center-thermal-pad land on the PCB with at least 8 thermal vias (0.3 mm drill, 1.0 mm pitch) connecting to a ground plane to achieve the 30 C/W theta-JA target. Keep high-current switching traces (relay drivers, motor drivers) away from ADC traces; route the ADC reference (AREF) capacitor within 10 mm of the pin and place a guard ring tied to AGND around sensitive analog signal traces. Exposed pad MUST be soldered to the PCB land for mechanical reliability and thermal performance.

Do not exceed 5.5 V on VCC - the ATmega2561 is not 3.3 V tolerant despite its AVR heritage. Do not connect JTAG pins (PF4-PF7/TDI/TMS/TCK/TDO) directly to external signals without considering that JTAG fuse programming can disable these as I/O. Brown-out detect should be enabled and tuned to 4.0 V or 2.7 V to prevent Flash corruption during supply transients. When migrating from ATmega1281 firmware, recompile with the ATmega2561 build profile in MCUdude MegaCore or AVR Studio to expose the larger Flash region - using the wrong linker script yields silently truncated firmware.

External memory interface (EBI/EMI) signals should be length-matched to within 5 mm if the bus runs above 8 MHz to avoid setup/hold violations; add 10-22 pF series damping resistors if ringing exceeds 0.5 Vpp. The JTAG TDO signal has a tri-state output and requires a pull-up of 10-47 kohm to avoid floating during scan chains. SPI signals should use a ground reference and series resistors if the cable length exceeds 50 mm, particularly when connecting to SD cards or radio modules.

Información de cumplimiento

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Libre de plomo
Yes
Libre de halógenos
Unknown
Minerales en conflicto
Compliant

ATMEGA2561-16MU is RoHS compliant per Microchip product page and is supplied in lead-free packaging. It is not AEC-Q100 qualified for automotive applications; AEC-Q100 grade parts in this family use a different part suffix. Halogen-free status not explicitly stated in the verified web data.

Datos verificados el: 2026-10-07 — datos verificados y seleccionados por el equipo de ingeniería de componentes de XAIPART

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