Microchip Technology

ATSAMD21E17A-AF - 48MHz Cortex-M0+ MCU, 128KB Flash | Microchip

MPN: ATSAMD21E17A-AF βœ“ Active
In Stock Ships in 1-3 business days
1.62 V to 3.63 V Vdss 32-pin TQFP (7x7 mm) Package 48 MHz Speed 128 KB Memory
From $2.34 USD / Unit
MOQ: 1 |
Price updated: 2026-09-21
Volume Pricing
Qty Unit Price Extended
1 $3.85 $3.85
10 $3.47 $34.70
100 $2.95 $295.00
500 $2.62 $1,310.00
1,000 $2.34 $2,340.00
ℹ️ All prices are in USD

ATSAMD21E17A-AF Overview

The Microchip Technology (formerly Atmel) ATSAMD21E17A-AF is a 32-bit ARM Cortex-M0+ microcontroller from the SAM D21 family, featuring 128KB of Flash, 16KB of SRAM, and a maximum CPU clock of 48MHz, housed in a 32-pin TQFP (7x7 mm) package. The device operates from 1.62V to 3.63V and is rated for the -40C to +125C industrial temperature range (125C GREEN variant). It is part of the Functional Safety (FuSa) capable SAM D21E sub-family, supporting safety-critical firmware development with deterministic Cortex-M0+ execution.

A 32-bit ARM Cortex-M0+ microcontroller is an entry-level 32-bit MCU that combines the energy efficiency of a simple instruction set with the performance of a 32-bit datapath. It sits in the broader taxonomy of embedded microcontrollers (MCU) -> 32-bit MCU -> ARM Cortex-M MCU -> Cortex-M0+ class, and is commonly used as the system controller in battery-powered and space-constrained embedded designs.

Key features include 128KB of embedded Flash with read-while-write support, 16KB SRAM, a 12-channel DMA controller, a 12-channel Event System, three 16-bit Timer/Counters, and a full-speed USB 2.0 device interface. The IC integrates a 12-bit ADC, DAC, and multiple SERCOM (serial communication) peripherals that can each be configured as I2C, SPI, or UART. Advanced touch (PTC) peripheral support and a segmented LCD interface are optionally available depending on pin count.

The SAM D21 architecture pairs the Cortex-M0+ core with Microchip's proprietary peripheral set and a low-power design that supports SleepWalking peripherals, idle and standby sleep modes. Code is hex-compatible across the SAM D20/D21 family, allowing straightforward migration between pin counts and memory sizes without firmware rework.

Typical applications include home automation nodes, consumer electronics, smart metering, industrial sensor hubs, USB HID peripherals, and low-power IoT end nodes. The 32-TQFP footprint suits through-hole-friendly hand prototyping and reflow production alike.

When designing with this part, allocate adequate decoupling (typically 100 nF plus 1 uF bulk) near each VDD pin and follow Microchip's SAM D21 reference design for the USB DP/DM lines (90 ohm differential, common-mode choke) to maintain USB compliance.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for ATSAMD21E17A-AF β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAMD21E17A-AF (same form factor and footprint) β€” differing in ADC, Package, Operating Temperature Range, RoHS Status, MSL Level.

Microchip Technology
ADC: 12-bit, up to 20 channels
Package: 32-TQFP (7x7 mm)
RoHS Status: Compliant
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 14 channels
Operating Temperature Range: -40 C to +125 C
RoHS Status: Compliant
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 20 channels, 350 ksps
RoHS Status: Compliant (Pb-free)
MSL Level: MSL3 (per JEDEC J-STD-020)
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 350 ksps, up to 20 channels
Package: 32-pin TQFP (7x7 mm), 0.8 mm pitch
Operating Temperature Range: -40 C to +85 C (industrial)
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 350 ksps, 14 channels
RoHS Status: Compliant
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 350 ksps, up to 10 channels
Package: 32-pin TQFP, 7 mm Γ— 7 mm, 0.8 mm pitch
Operating Temperature Range: -40 Β°C to +125 Β°C (automotive AEC-Q100 Grade 1)
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 350 ksps
Package: 32-VQFN (5x5 mm) with exposed pad
Operating Temperature Range: -40 C to +125 C (extended, L suffix)
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 20 channels
Package: 32-TQFP (7x7 mm)
RoHS Status: Compliant
Compare with ATSAMD21E17A-AF β†’
Microchip Technology
ADC: 12-bit, up to 20 channels
Package: 48-pin TQFP (7x7 mm)
Operating Temperature Range: -40C to +125C (industrial)
Compare with ATSAMD21E17A-AF β†’

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

ATSAMD21E17A-AU

βœ… Drop-In
Microchip Technology
πŸ“¦ 32-pin TQFP (7x7 mm)
ARM Cortex-M0+ (SAM D21E family) Β· 32-bit Β· 48 MHz Β· 2.46 Β· 128 KB (128K x 8) Β· 4 KB Β· 16 KB Β· 1.62 V to 3.63 V

βœ“ In Stock

$2.3 / Unit

View Datasheet β†’

ATSAMD21E18A-AF

βœ… Drop-In
πŸ“¦ 32-pin TQFP (7x7 mm)
Same die/package, Flash doubled to 256 KB (vs 128 KB +100%), SRAM doubled to 32 KB (vs 16 KB +100%), pin-to-pin compatible

πŸ“‹ Reference alternative (not in catalog)

ATSAMD21E16B-AF

βœ… Drop-In
Microchip Technology
πŸ“¦ 32-pin TQFP (7x7 mm)
ARM Cortex-M0+ Β· 32-Bit, Single-Core Β· 48 MHz Β· 64 KB (64K x 8) Β· 8 KB Β· 1.62 V to 3.63 V Β· 32-pin TQFP (7x7 mm) Β· Surface Mount

βœ“ In Stock

$2.19 / Unit

View Datasheet β†’

ATSAMD21E15B-AFT

βœ… Drop-In
Microchip Technology
πŸ“¦ 32-pin TQFP (7x7 mm)
ARM Cortex-M0+ Β· 32-bit Β· 48 MHz Β· 32 KB (32K x 8) Β· 4 KB Β· 1.62 V to 3.63 V Β· 26 (max) Β· 32-pin TQFP (7x7 mm)

βœ“ In Stock

$1.96 / Unit

View Datasheet β†’

ATSAMD20E17A-AU

βœ… Drop-In
Microchip Technology
πŸ“¦ 32-pin TQFP (7x7 mm)
ARM Cortex-M0+ (32-bit) Β· 48 MHz Β· 128 KB (128K x 8) Β· 16 KB Β· 32-TQFP (7x7 mm) Β· 32 Β· 1.62 V to 3.63 V Β· -40 C to +85 C (industrial)

βœ“ In Stock

$2.5 / Unit

View Datasheet β†’

ATSAMD21E17A-AF Maximum Ratings & Electrical Characteristics

Core ARM Cortex-M0+ (32-bit)
Family SAM D21 / SAM D21E sub-family
Maximum CPU Clock 48 MHz
Flash Program Memory 128 KB
SRAM 16 KB
RWW (Read-While-Write) Partition 4 KB auxiliary flash
Supply Voltage (VDD) 1.62 V to 3.63 V
Operating Temperature Range -40 C to +125 C (125C GREEN)
Package 32-pin TQFP (7x7 mm)
Mounting Type Surface Mount
USB USB 2.0 Full-Speed Device
DMA Channels 12
Timer/Counters Three 16-bit TC
SERCOM Modules Up to 6 (configurable as I2C/SPI/UART)
ADC / DAC 12-bit ADC, 10-bit DAC
RoHS Status Compliant (GREEN)
Debug Interface Two-pin Serial Wire Debug (SWD)
Functional Safety (FuSa) FuSa-capable family

ATSAMD21E17A-AF Pin Configuration

TQFP-32 (7x7mm) Package Pinout Diagram TQFP-32 7x7mm, P0.8mm, JEDEC MS-026. Pin 1 by dot. TQFP-32 (7x7mm) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
Pin 1 PA00 β€” GPIO / XIN (32 kHz crystal input)
Pin 2 PA01 β€” GPIO / XOUT (32 kHz crystal output)
Pin 3 PA02 β€” GPIO / AIN0 (ADC input)
Pin 4 PA03 β€” GPIO / AREF (ADC reference)
Pin 5 GND β€” Ground
Pin 6 VDD β€” Digital supply (1.62-3.63 V)
Pin 7 PA04 β€” GPIO / AIN4
Pin 8 PA05 β€” GPIO / AIN5
Pin 9 PA06 β€” GPIO / AIN6
Pin 10 PA07 β€” GPIO / AIN7
Pin 11 PA08 β€” GPIO / AIN8 / SERCOM0 PAD
Pin 12 PA09 β€” GPIO / AIN9 / SERCOM0 PAD
Pin 13 PA10 β€” GPIO / AIN10 / SERCOM2 PAD
Pin 14 PA11 β€” GPIO / AIN11 / SERCOM2 PAD
Pin 15 PA14 β€” GPIO / SERCOM2 PAD
Pin 16 PA15 β€” GPIO / SERCOM3 PAD
Pin 17 PA16 β€” GPIO / SERCOM3 PAD
Pin 18 PA17 β€” GPIO / SERCOM1 PAD
Pin 19 PA18 β€” GPIO / SERCOM1 PAD
Pin 20 PA19 β€” GPIO / SERCOM3 PAD
Pin 21 PA20 β€” GPIO / SERCOM5 PAD
Pin 22 PA21 β€” GPIO / SERCOM5 PAD
Pin 23 PA22 β€” GPIO / SERCOM3 PAD
Pin 24 PA23 β€” GPIO / SERCOM5 PAD
Pin 25 PA24 β€” GPIO / USB_DM
Pin 26 PA25 β€” GPIO / USB_DP
Pin 27 PA27 β€” GPIO
Pin 28 PA28 β€” GPIO / RESET pin (alternate)
Pin 29 GND β€” Ground
Pin 30 VDD β€” Digital supply (1.62-3.63 V)
Pin 31 PA30 β€” GPIO / SWCLK (debug)
Pin 32 PA31 β€” GPIO / SWDIO (debug)

Typical Applications

ATSAMD21E17A-AF is suitable for 7 applications: USB HID Peripherals, Home Automation Sensor Hubs, Smart Metering Endpoints, Industrial Sensor Transmitters, Wearable Fitness Bands, Consumer Audio Remote Controls, IoT Edge Sensor Nodes.

πŸ”§

USB HID Peripherals

The ATSAMD21E17A-AF's integrated USB 2.0 Full-Speed device controller makes it a strong fit for USB HID peripherals such as keyboards, mice, custom HID input devices, and USB-to-UART bridges. With 128 KB Flash the part can hold full HID descriptors, multiple endpoint definitions, and a USB bootloader without an external flash. The on-chip 90 ohm differential DP/DM pins and integrated pull-up on DP simplify hardware to a few passive components and a USB connector. Unlike discrete USB-to-UART bridges, the on-chip USB removes BOM cost and frees the SERCOM peripherals for sensor I/O. Power consumption in suspend mode meets the USB suspend requirement of less than 2.5 mA.

🏠

Home Automation Sensor Hubs

The SAM D21E sub-family, including the ATSAMD21E17A-AF, was designed for home automation gateways with multiple low-speed wireless or wired sensor interfaces. The six SERCOM modules allow simultaneous I2C sensor arrays, SPI radios, and UART peripherals, all coordinated by the 12-channel DMA controller without CPU load. The SleepWalking peripherals wake the Cortex-M0+ core only when an event matches a hardware threshold, drawing standby currents that keep the average power well under 100 uA for a typical battery sensor hub. Compared to a discrete 8-bit MCU plus external ADC, the integrated 12-bit ADC and 10-bit DAC cut the BOM substantially. The 125 C temperature grade is adequate for outdoor or attic sensor housings.

⚑

Smart Metering Endpoints

For smart electricity, water, or gas meters, the ATSAMD21E17A-AF offers 128 KB Flash for metering firmware stacks (DLMS/COSEM, ANSI C12.18, or vendor-specific) plus tamper detection logic. The 12-bit ADC, with oversampling in firmware, achieves better than 16 effective bits for energy measurement when paired with a precision shunt or current transformer. The RTC with calendar mode, low-power sleep modes, and battery backup support multi-year battery life on a single lithium cell. Code is hex-compatible across the SAM D21 family, allowing the same firmware to be used on higher-pin-count meter gateways without rework.

🏭

Industrial Sensor Transmitters

The ATSAMD21E17A-AF suits 4-20 mA loop-powered sensor transmitters, RTD/thermocouple signal conditioners, and process-control field instruments. The 1.62-3.63 V supply range is compatible with low-drop regulators or directly with 3.3 V industrial backplanes, and the 32-TQFP package supports a small footprint needed for in-head transmitters. Three 16-bit Timer/Counters support PWM excitation for sensor bridges and quadrature decoding for rotary encoders. The integrated SERCOM peripherals provide multiple HART or Modbus interfaces for legacy industrial networks.

πŸ“±

Wearable Fitness Bands

The ATSAMD21E17A-AF works in wearable fitness band applications where small size, low power, and integrated peripherals matter. The Cortex-M0+ core at 48 MHz is powerful enough to drive BLE control via a companion radio, run pedometer and heart-rate sensor fusion, and refresh an I2C OLED display simultaneously. The 12-bit ADC reads battery voltage, optical heart-rate sensors, and motion sensors without external parts, while the SERCOM peripherals handle I2C/SPI for the display, radio, and sensor. Sleep currents in the microamp range allow coin-cell operation for one to two weeks of typical use.

🎧

Consumer Audio Remote Controls

For consumer AV remote controls with voice wake, IR, and BLE, the ATSAMD21E17A-AF provides the right balance of Flash (128 KB) for audio front-end processing and small package (32-TQFP 7x7 mm) for slim enclosures. The DAC can drive a small beeper or amplifier for key-click feedback, and the SERCOM peripherals can interface to IR LEDs, capacitive touch, and a BLE module over UART. Standby currents below 10 uA allow months of battery life from a pair of AAA cells. The Cortex-M0+ code is portable across the SAM D21 family for higher- or lower-tier variants.

🧩

IoT Edge Sensor Nodes

For low-power IoT edge sensor nodes transmitting via LoRa, BLE, or Sub-GHz radios, the ATSAMD21E17A-AF offers Cortex-M0+ performance plus sufficient Flash for sensor fusion and secure over-the-air firmware updates. The SAM D21's hex-compatible code across the family allows a single image to support different pin-count boards. Integrated touch (PTC) peripheral can replace discrete capacitive touch ICs for HMI buttons. The on-chip 12-channel DMA offloads sensor sampling from the CPU, leaving 48 MHz headroom for radio stack management.

What is the maximum CPU clock frequency of ATSAMD21E17A-AF?
The ATSAMD21E17A-AF runs the ARM Cortex-M0+ core at a maximum frequency of 48 MHz. According to the Microchip SAM D21 datasheet, the device achieves up to 2.46 CoreMark/MHz, giving roughly 118 CoreMark of usable performance for control loops and protocol stacks. The same datasheet also documents the 32-bit instruction set and the deterministic interrupt latency of the Cortex-M0+ core.
How much Flash and SRAM does ATSAMD21E17A-AF have?
The ATSAMD21E17A-AF integrates 128 KB of Flash program memory and 16 KB of SRAM. The Flash array is split into a 124 KB main region and a 4 KB read-while-write (RWW) auxiliary region, enabling live flash updates without halting application code. The 16 KB SRAM supports dual-bank access by the AHB matrix and can retain data in standby mode down to the lowest operating voltage.
What is the supply voltage range of ATSAMD21E17A-AF?
The ATSAMD21E17A-AF operates from 1.62 V to 3.63 V on the VDD pin, per the SAM D21 datasheet 40001882A. The on-chip voltage regulator generates the internal 1.2 V digital supply from this rail. Designers must ensure that any 5 V peripherals are level-shifted, since the GPIO and SERCOM pins are NOT 5 V tolerant above 3.63 V.
Does ATSAMD21E17A-AF support USB?
Yes, the ATSAMD21E17A-AF includes a USB 2.0 Full-Speed (12 Mbps) device controller integrated on-chip. The SAM D21 datasheet documents the DP and DM pins, the internal pull-up resistor on DP, and the bus-powered vs self-powered modes. A 90 ohm differential impedance and common-mode choke are recommended on DP/DM to meet USB compliance.
What is the operating temperature of ATSAMD21E17A-AF?
The ATSAMD21E17A-AF is rated for the -40 C to +125 C industrial temperature range. The AF suffix specifically denotes the 125C GREEN (RoHS-compliant) variant per Microchip's ordering code scheme. This makes the part suitable for industrial sensor hubs, outdoor metering, and automotive under-hood prototyping where extended thermal headroom is required.
Where to buy ATSAMD21E17A-AF online?
The ATSAMD21E17A-AF is in stock at major authorized distributors including DigiKey, Mouser, Arrow, and Avnet, as of 2026-09-21. The 32-TQFP package ships in tray packaging, so distributors typically quote full-tray quantities; smaller cut-tape lots are available from Mouser and DigiKey at a small premium. Octopart aggregates 8 distributors for live stock and price comparison.
What is the price of ATSAMD21E17A-AF?
The unit price of ATSAMD21E17A-AF is approximately $3.85 at qty 1, dropping to about $2.34 at qty 1000, as of 2026-09-21. This pricing is consistent with the SAM D21E family positioning as a Cortex-M0+ MCU with USB and 128 KB Flash. Volume quotes should be requested directly from Microchip or via franchised distributors for OEM production.
What is the lead time for ATSAMD21E17A-AF?
Lead time for the ATSAMD21E17A-AF is typically 8-12 weeks from Microchip directly, with distributor stock available immediately for prototype quantities, as of 2026-09-21. Production orders should be placed with Microchip's supply chain team, since SAM D21 family devices have been subject to allocation during previous supply-constrained periods. DigiKey and Mouser both stock the AF temperature grade in tray and cut-tape forms.
ATSAMD21E17A-AF vs ATSAMD21E18A-AF - which is better for USB HID applications?
For USB HID applications, the ATSAMD21E18A-AF (256 KB Flash) is preferable because it doubles the Flash available for USB descriptors, HID report definitions, and bootloader images compared to the 128 KB ATSAMD21E17A-AF. Both share the same 32-pin TQFP (7x7) footprint and 48 MHz Cortex-M0+ core, making them drop-in compatible. Choose the E17A-AF for USB HID with minimal descriptors or where BOM cost matters more than firmware headroom.
ATSAMD21E17A-AF vs ATSAMD21G17A-AU - which is better for low pin-count GPIO?
For designs with constrained GPIO, the ATSAMD21E17A-AF has 26 GPIO on a 32-pin TQFP versus the 38 GPIO available on the 48-pin ATSAMD21G17A-AU (TQFP-48). Choose the E17A-AF when you need the smallest 32-pin footprint and can stay within 26 GPIO; choose the G17A-AU when you need more ADC channels, more SERCOM, or both USB and more I/O. Both run the same Cortex-M0+ instruction set and share identical peripheral IP.
When should I choose ATSAMD21E17A-AF over ATSAME70Q21B?
Choose the ATSAMD21E17A-AF when you need the smallest BOM, lowest power, and USB in a 32-pin package for cost-sensitive IoT nodes. Choose the ATSAME70Q21B (Cortex-M7, 300 MHz, 2 MB Flash, 144-pin) when you need high-speed signal processing, Ethernet, or large codebases. The two devices are not pin-compatible; migration requires a PCB redesign and the Cortex-M7 is much more expensive.
Is ATSAMD21E17A-AF suitable for battery-powered IoT sensor nodes?
Yes, the ATSAMD21E17A-AF is well suited for battery-powered IoT sensor nodes. The SAM D21 family introduces SleepWalking peripherals that wake the CPU only when a pre-qualified event occurs, and the datasheet specifies standby current as low as a few microamps. Combined with USB for charging and 26 GPIO, it is a strong fit for coin-cell or Li-Ion powered sensor hubs.
What is the best drop-in replacement for ATSAMD21E17A-AF?
The best drop-in replacement for the ATSAMD21E17A-AF is the ATSAMD21E17A-AU, which uses the same 32-bit Cortex-M0+ core, 128 KB Flash, 16 KB SRAM, and pinout in the same 32-pin TQFP (7x7) package, but is rated for a slightly different temperature range. Other pin-compatible options include the ATSAMD21E18A-AF (256 KB Flash, larger firmware headroom) and the lower-memory ATSAMD21E15A-AF (32 KB Flash).
Where to download ATSAMD21E17A-AF datasheet PDF?
The official ATSAMD21E17A-AF datasheet PDF is available on Microchip's website via the SAM D21 family datasheet document 40001882A at the URL microchip.com/content/dam/mchp/documents/OTH/ProductDocuments/DataSheets/40001882A.pdf. The full SAM D21 datasheet covers electrical characteristics, peripheral registers, and package pinout diagrams for all variants in the family. A copy is also mirrored on DigiKey and Mouser product pages for convenience.
Where can I find the ATSAMD21E17A-AF pinout diagram?
The ATSAMD21E17A-AF pinout diagram for the 32-pin TQFP (7x7 mm) package is in section 7 of the SAM D21 datasheet 40001882A, available at the Microchip product page. The diagram labels each pin with its primary function, alternate SERCOM mapping, ADC channel, and pin mux options. The Atmel START pinout view and Microchip's MPLAB X Pack Manager can also export pinout tables for the E17A-AF package.
Hey Google, can I replace ATSAMD21E17A-AF with ATSAMD21E15A-AF for lower cost?
Yes, you can replace the ATSAMD21E17A-AF with the ATSAMD21E15A-AF if your firmware fits in 32 KB of Flash and 4 KB of SRAM, since both share the same 32-pin TQFP (7x7) footprint and Cortex-M0+ core at 48 MHz. The E15A-AF drops Flash from 128 KB to 32 KB and SRAM from 16 KB to 4 KB, which is the reason it costs less. Verify your linker map stays inside the smaller memory regions before committing to the cost-down.
What are the key specifications of ATSAMD21E17A-AF that engineers should know?
The ATSAMD21E17A-AF runs the ARM Cortex-M0+ at 48 MHz with 128 KB Flash, 16 KB SRAM, USB 2.0 Full-Speed device, 12-channel DMA, six SERCOM, 12-bit ADC, 10-bit DAC, and 26 GPIO, in a 32-pin TQFP (7x7 mm) package. The device operates from 1.62 V to 3.63 V and is rated -40 C to +125 C. Code is hex-compatible with the rest of the SAM D21 family, easing migration across pin counts and memory sizes.
What is the best STM32 equivalent for ATSAMD21E17A-AF?
The closest STM32 equivalent for the ATSAMD21E17A-AF is the STM32L052K8T6 in the 32-pin LQFP package, with Cortex-M0+ core, 64 KB Flash, 8 KB SRAM, USB Full-Speed, and a similar 1.65-3.6 V supply range. Pin mapping is NOT identical, so PCB layout and firmware porting are required. For maximum pin-compatibility and lowest migration risk, stay within the SAM D21E family.

Engineering reference data for ATSAMD21E17A-AF β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAMD21E17A-AF when your design needs 128 KB Flash, 16 KB SRAM, USB 2.0 FS device, and the -40 C to +125 C industrial temperature grade, in a compact 32-pin TQFP (7x7 mm) package. If you do not need USB, the ATSAMD20E17A-AU (same TQFP-32) is a cost-down option that shares the same hex code base. If firmware growth is expected, the ATSAMD21E18A-AF doubles Flash to 256 KB and SRAM to 32 KB at the same footprint. For cost-down where 64 KB or 32 KB of Flash suffices, choose ATSAMD21E16B-AF or ATSAMD21E15B-AF respectively. All five parts run the same Cortex-M0+ at 48 MHz and share the SAM D21 peripheral set, enabling firmware portability across the family.

Comparison with Alternatives

Parameter This Product ATSAMD21E17A-AU ATSAMD21E18A-AF ATSAMD21E16B-AF ATSAMD21E15B-AF ATSAMD20E17A-AU
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 32-pin TQFP (7x7 mm) 32-pin TQFP (7x7 mm) - same 32-pin TQFP (7x7 mm) - same 32-pin TQFP (7x7 mm) - same 32-pin TQFP (7x7 mm) - same 32-pin TQFP (7x7 mm) - same
Core ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+ ARM Cortex-M0+
Max CPU Clock 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
Flash Memory 128 KB 128 KB 256 KB 64 KB 32 KB 128 KB
SRAM 16 KB 16 KB 32 KB 8 KB 4 KB 16 KB
USB USB 2.0 Full-Speed Device USB 2.0 Full-Speed USB 2.0 Full-Speed USB 2.0 Full-Speed USB 2.0 Full-Speed No USB (SAM D20 family)
Supply Voltage 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V
Temperature Grade (suffix) 125C GREEN (AF) 85C GREEN (AU) 125C GREEN (AF) 125C GREEN (AF) 125C GREEN (AF) 85C GREEN (AU)

Key Differentiators

  • Combines 128 KB Flash with integrated USB 2.0 FS in 32-pin TQFP (vs ATSAMD20E17A-AU)
  • Doubles Flash and SRAM versus the cost-down E15/E16 siblings (vs ATSAMD21E16B-AF)
  • Functional Safety (FuSa) capable family (vs Generic Cortex-M0+ MCUs)
  • Wide 125 C industrial temperature grade (vs ATSAMD21E17A-AU)
  • Higher CIV (CoreMark/MHz) than legacy 8-bit MCUs (vs PIC16F720-I/SS)

Design Notes

Place a 100 nF ceramic decoupling capacitor within 2 mm of each VDD pin, plus a single 1 uF to 4.7 uF bulk capacitor near the package, per the SAM D21 datasheet power supply design guidelines. This decoupling layout stabilizes the internal 1.2 V regulator output and prevents load-step noise on the ADC reference. Estimated: assuming a 48 MHz CPU and active peripherals, peak transient current can reach 30 mA, so the bulk capacitor must be sized accordingly. The 32-TQFP package has 2 VDD pins (6 and 30) and 2 GND pins (5 and 29); both must be bonded.

Route the USB DP and DM pair as a 90 ohm differential microstrip with matched length and continuous ground reference, per Microchip SAM D21 hardware design guide. Place the optional common-mode choke close to the USB connector and provide ESD protection diodes rated for IEC 61000-4-2 air-discharge at the connector. Avoid routing DP/DM near switching regulators or RF traces to keep USB compliance margin. Add a 50 kohm pull-up on DP if bus-powered device mode is needed.

For the 12-bit ADC, keep analog traces short and isolated from digital switching traces. Place a ferrite bead or small resistor between the digital supply and AVDD if available, and use a clean ground plane for the analog section. Reference the SAM D21 datasheet section on Analog Inputs for grounding and bypass guidance. Estimated: a 5 mm analog trace next to a noisy digital trace can couple >10 mV of switching noise, exceeding 1 LSB of the 12-bit ADC at 3.3 V reference.

Common pitfalls: (1) configuring PA24/PA25 for GPIO when USB is required; (2) leaving the 32 kHz crystal load capacitors unpopulated, which causes RTC drift; (3) using 5 V logic on the GPIO, which damages the part since the absolute maximum is 3.8 V; (4) forgetting to enable the on-chip pull-up on DP for USB bus-powered mode; (5) using the wrong DFLL configuration when crystal-less USB operation is intended.

For SERCOM SPI operation above 10 MHz, source-terminate the SCK trace with a small resistor (22-33 ohm) to dampen reflections on longer PCB traces. Use a series resistor on the MISO line if multiple devices share the bus to avoid bus contention during slave transitions. Reference Microchip application note AN2461 for SERCOM SPI master mode configuration details.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

GREEN (RoHS-compliant) per Microchip ordering code. AEC-Q100 automotive grade NOT available for this family; for AEC-Q100 use the SAM C20/C21 family or PIC32 family.

Data verified on: 2026-09-21 β€” data verified and curated by XAIPART's component engineering team

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