Microchip Technology

ATSAMD21E17A-AU - ARM Cortex-M0+ 48MHz 128KB MCU 32-TQFP | Microchip

MPN: ATSAMD21E17A-AU ✓ Active
In Stock Ships in 1-3 business days
1.62 V to 3.63 V Vdss 32-pin TQFP (7x7 mm), 0.8 mm pitch Package 48 MHz Speed 128 KB (128K x 8) Memory
From $2.3 USD / Unit
MOQ: 1 |
Price updated: 2026-09-21
Volume Pricing
Qty Unit Price Extended
1 $4.2 $4.20
10 $3.78 $37.80
100 $3.35 $335.00
500 $2.99 $1,495.00
1,000 $2.65 $2,650.00
3,000 $2.3 $6,900.00
ℹ️ All prices are in USD

ATSAMD21E17A-AU Overview

The Microchip (formerly Atmel) ATSAMD21E17A-AU is a 32-bit ARM Cortex-M0+ microcontroller from the SAM D21E family, featuring a 48 MHz CPU core, 128 KB of Flash, 16 KB of SRAM, and a full-speed USB 2.0 interface, housed in a 32-pin TQFP (7x7 mm) package. It operates from a 1.62 V to 3.63 V supply and integrates a 12-channel DMA controller, a 12-channel Event System, three 16-bit Timer/Counters, SERCOM peripherals, a 12-bit ADC, and a 10-bit DAC, all within an ultra-low-power architecture that includes SleepWalking peripherals and Idle/Standby sleep modes.

A 32-bit ARM Cortex-M0+ microcontroller is a low-power, high-efficiency embedded processor that uses the 32-bit ARM instruction set optimized for energy-constrained applications. Cortex-M0+ cores deliver roughly 2.46 CoreMark/MHz while consuming very low active current, and they sit inside the broader taxonomy of microcontroller -> embedded controller -> SoC -> semiconductor. The SAM D21 family specifically targets battery-powered home automation, consumer, metering, and industrial designs where deterministic real-time response and rich peripheral integration matter more than raw MHz.

Key differentiating features of the ATSAMD21E17A-AU include 128 KB self-programmable Flash with 4 KB read-while-write region, full-speed USB 2.0 with on-chip transceiver and 2-KB/2-KB endpoint RAM, six SERCOM serial communication channels, and AEC-Q100-qualified variants available in the same family. The device also integrates a 32-bit Real-Time Counter (RTC) with calendar mode, capacitive touch support via the Peripheral Touch Controller (PTC), and a hardware Cryptographic Engine supporting AES and True Random Number Generator on related family members.

The architecture centers on a single-cycle I/O port bus connected through a multi-layer AHB/APB matrix, allowing DMA-driven data movement between peripherals and memory without CPU intervention. The 1.62 V minimum VDDIN extends the usable supply range down to a single 1.8 V rail, while the on-chip voltage regulator supports core operation from VDDIO and a separate VDDIN domain for analog and USB PHY supply. Sleep modes per technology - Idle, Standby, Backup, and Off - reduce quiescent current to the microamp range, and SleepWalking peripherals can wake the CPU only on qualified events to minimize wake-sleep duty cycling.

Typical applications include smart-home sensors and HMI panels, industrial metering and PLC I/O modules, USB HID peripherals such as keyboards and custom input controllers, low-power wireless sensor nodes paired with an external radio, fitness wearables and consumer health devices, and capacitive touch user interfaces for appliances. The wide 1.62-3.63 V supply range and USB PHY make it a natural fit for battery-powered devices that also expose a USB charging or data port.

When designing with the ATSAMD21E17A-AU, place the bypass network (typically 100 nF + 4.7 uF bulk) within 5 mm of VDDIN and VDDIO, route the USB DP/DM pair as a 90 ohm differential with a common-mode choke for EMI, and use the PTC-driven driven shield for moisture-tolerant touch electrodes. The 32-TQFP allows optical inspection and hand rework, but the 0.8 mm pitch still requires a 4-layer PCB with solid ground pour under the exposed pad for thermal dissipation.

This page synthesizes distributor pricing for the ATSAMD21E17A-AU, drop-in alternatives within the SAM D21E family and across vendors, and practical design notes not found in the standalone manufacturer datasheet, giving engineers a single reference for sourcing, comparison, and layout decisions.

Drop-in alternatives for ATSAMD21E17A-AU — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAMD21E17A-AU (same form factor and footprint) — differing in Package, ADC, Operating Temperature, SERCOM Modules, Operating Temperature Range.

Microchip Technology
Package: 32-TQFP (7x7 mm)
ADC: 12-bit, up to 20 channels
Operating Temperature: -40 C to +85 C (industrial)
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 32-pin TQFP (7x7 mm)
ADC: 12-bit, 8 channels
Operating Temperature: -40C to +85C
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 32-pin TQFP
ADC: 12-bit, 20 channels
Operating Temperature: -40 °C to +85 °C (industrial)
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 32-TQFP (7x7 mm)
ADC: 12-bit, up to 350 ksps
Operating Temperature: -40C to +85C
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 32-pin TQFP (7x7 mm)
SERCOM Modules: Up to 6 (configurable as I2C/SPI/UART)
Operating Temperature Range: -40 C to +125 C (125C GREEN)
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 32-pin TQFP, 7 mm × 7 mm, 0.8 mm pitch
ADC: 12-bit, up to 350 ksps, up to 10 channels
SERCOM Modules: 6 (configurable as UART / SPI / I²C)
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 32-VQFN (5x5 mm) with exposed pad
ADC: 12-bit, up to 350 ksps
SERCOM Modules: 6 (each reconfigurable as I2C/SPI/UART)
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Microchip Technology
Package: 32-TQFP (7x7 mm)
ADC: 12-bit, up to 20 channels
Operating Temperature: -40 C to +125 C
Compare with ATSAMD21E17A-AU →
Microchip Technology
Package: 48-pin TQFP (7x7 mm)
ADC: 12-bit, up to 20 channels
Operating Temperature: -40C to +125C (Automotive Grade)
Compare with ATSAMD21E17A-AU →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAMD21E17A-AUT

✅ Drop-In
📦 32-TQFP (7x7 mm)
Same die and TQFP-32 footprint; tape-and-reel packaging variant (-AUT suffix)

📋 Reference alternative (not in catalog)

ATSAMD21E17A-AF

✅ Drop-In
Microchip Technology
📦 32-TQFP (7x7 mm)
ARM Cortex-M0+ (32-bit) · SAM D21 / SAM D21E sub-family · 48 MHz · 128 KB · 16 KB · 4 KB auxiliary flash · 1.62 V to 3.63 V · -40 C to +125 C (125C GREEN)

✓ In Stock

$2.34 / Unit

View Datasheet →

ATSAMD21E16A-AU

✅ Drop-In
📦 32-TQFP (7x7 mm)
Same SAM D21E die and TQFP-32 footprint; Flash 64 KB vs 128 KB (-50%); SRAM 8 KB vs 16 KB (-50%); otherwise identical

📋 Reference alternative (not in catalog)

ATSAMD21E15B-AU

✅ Drop-In
Microchip Technology
📦 32-TQFP (7x7 mm)
ARM Cortex-M0+ (32-bit) · 48 MHz · 32 KB · 4 KB · 1.62 V to 3.6 V (3.3 V nominal) · -40 °C to +85 °C (industrial) · 32-pin TQFP · Up to 26

✓ In Stock

$1.45 / Unit

View Datasheet →

ATSAMD21E16B-AU

✅ Drop-In
Microchip Technology
📦 32-TQFP (7x7 mm)
ARM Cortex-M0+ · 32-Bit Single-Core · 48 MHz · 2.46 CoreMark/MHz · 64 KB (32K x 16) · 8 KB · 1.62 V to 3.63 V · Up to 26

✓ In Stock

$2.1 / Unit

View Datasheet →

ATSAMD21E17A-AU Maximum Ratings & Electrical Characteristics

Core Architecture ARM Cortex-M0+ (SAM D21E family)
CPU Bit Width 32-bit
Maximum CPU Frequency 48 MHz
CoreMark/MHz 2.46
Program Flash Memory 128 KB (128K x 8)
RWW (Read-While-Write) Flash Section 4 KB
SRAM 16 KB
Operating Voltage Range (VDDIN) 1.62 V to 3.63 V
USB Interface USB 2.0 Full-Speed (12 Mbps) with on-chip transceiver
SERCOM Channels 6 (configurable as UART/SPI/I2C)
Timer/Counters Three 16-bit TC, one 32-bit TCC, one 24-bit RTC
ADC 12-bit, up to 350 ksps, up to 20 channels
DAC 10-bit, 1 channel
DMA Controller 12 channels
Package 32-pin TQFP (7x7 mm), 0.8 mm pitch
Operating Temperature Range -40 C to +85 C (industrial)
Mounting Type Surface Mount
MSL Level 3 (per JEDEC J-STD-020)
RoHS Status Compliant
Functional Safety (FuSa) SAM D21E family supports FuSa variants

ATSAMD21E17A-AU Pin Configuration

TQFP-32 (7x7mm) Package Pinout Diagram TQFP-32 7x7mm, P0.8mm, JEDEC MS-026. Pin 1 by dot. TQFP-32 (7x7mm) 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
Pin 1 PA00 — General-purpose I/O / XIN (external clock input)
Pin 2 PA01 — General-purpose I/O / XOUT (external clock output)
Pin 3 PA02 — General-purpose I/O / AIN[0] (analog input)
Pin 4 PA03 — General-purpose I/O / AIN[1] / VREFA
Pin 5 PA04 — General-purpose I/O / AIN[2]
Pin 6 PA05 — General-purpose I/O / AIN[3]
Pin 7 PA06 — General-purpose I/O / AIN[4]
Pin 8 PA07 — General-purpose I/O / AIN[5]
Pin 9 VDDIO — Digital I/O supply voltage
Pin 10 GND — Ground
Pin 11 PA08 — General-purpose I/O / AIN[6] / SERCOM0 PAD0
Pin 12 PA09 — General-purpose I/O / AIN[7] / SERCOM0 PAD1
Pin 13 PA10 — General-purpose I/O / SERCOM0 PAD2
Pin 14 PA11 — General-purpose I/O / SERCOM0 PAD3
Pin 15 VBUS — USB VBUS detect
Pin 16 DM — USB D- data line
Pin 17 DP — USB D+ data line
Pin 18 GND — Ground
Pin 19 VDDIN — Main supply voltage input
Pin 20 PA12 — General-purpose I/O / SERCOM2 PAD0
Pin 21 PA13 — General-purpose I/O / SERCOM2 PAD1
Pin 22 PA14 — General-purpose I/O / SERCOM2 PAD2
Pin 23 PA15 — General-purpose I/O / SERCOM2 PAD3
Pin 24 PA16 — General-purpose I/O / SERCOM1 PAD0
Pin 25 PA17 — General-purpose I/O / SERCOM1 PAD1
Pin 26 PA18 — General-purpose I/O / SERCOM1 PAD2
Pin 27 PA19 — General-purpose I/O / SERCOM1 PAD3
Pin 28 PA20 — General-purpose I/O / SERCOM3 PAD0
Pin 29 PA21 — General-purpose I/O / SERCOM3 PAD1
Pin 30 PA22 — General-purpose I/O / SERCOM3 PAD2
Pin 31 PA23 — General-purpose I/O / SERCOM3 PAD3
Pin 32 RESET — Reset input, active low

Typical Applications

ATSAMD21E17A-AU is suitable for 7 applications: Smart-Home Sensor Hubs, USB HID Input Devices, Industrial Metering & PLC I/O, Capacitive Touch User Interfaces, Battery-Powered Wearables, Consumer Appliance Control Boards, Educational & Maker Development.

🧩

Smart-Home Sensor Hubs

The ATSAMD21E17A-AU fits smart-home sensor hubs because its 128 KB Flash and 16 KB SRAM comfortably host Zigbee or Matter-over-Thread application stacks alongside peripheral drivers, while the 6 SERCOM channels drive I/U-bus sensor arrays and the 12-bit ADC samples environmental data at low active current. Placed as the main controller on a 1.8-3.3 V battery or USB-C rail, it consumes only a few hundred microamps in active mode and drops below 5 uA in Standby with the 32-bit RTC keeping wall-clock time. The integrated USB 2.0 Full-Speed interface supports firmware update over USB-C without an external PHY, dramatically reducing BOM cost.

🎮

USB HID Input Devices

The ATSAMD21E17A-AU is ideal for USB HID input devices - keyboards, mice, custom input controllers, and gamepads - because the integrated USB 2.0 Full-Speed device controller with on-chip transceiver eliminates the external PHY that older microcontrollers required. The 48 MHz Cortex-M0+ core runs USB stacks, debouncing, and capacitive touch handling in a single chip, while the Peripheral Touch Controller (PTC) supports up to 256 touch buttons directly. End products typically run at 3.3 V from a USB-C VBUS rail, drawing under 50 mA total - well within USB default-current limits.

🏭

Industrial Metering & PLC I/O

The ATSAMD21E17A-AU serves industrial metering and PLC I/O modules because its 12-bit 350 ksps ADC samples voltage and current channels fast enough for power-metering class accuracy when paired with external anti-alias filtering. The 6 SERCOM channels simultaneously drive isolated UART, RS-485, SPI display, and I2C EEPROM buses, while the 12-channel DMA offloads per-sample processing from the 48 MHz CPU. Operating from -40 C to +85 C, the part handles factory floor environments and integrates a 32-bit RTC for time-stamped logging over Modbus or CAN.

💡

Capacitive Touch User Interfaces

The ATSAMD21E17A-AU powers capacitive touch user interfaces for appliances and consumer electronics because the integrated Peripheral Touch Controller (PTC) supports up to 256 self-capacitance or mutual-capacitance electrodes with driven shield for moisture tolerance. Combined with the 10-bit DAC for haptic or LED backlight driving and the 6 SERCOM channels for display and audio, a single chip implements a complete capacitive keypad + TFT or segment UI. SleepWalking peripherals keep idle current low while continuing to scan electrodes at a slow rate for proximity wake.

📱

Battery-Powered Wearables

The ATSAMD21E17A-AU fits battery-powered wearables such as fitness bands and medical patches because its Idle and Standby modes drop quiescent current below 5 uA while the 32-bit RTC keeps accurate time-of-day for sleep tracking. The 1.62-3.63 V supply range accepts a single Li-Ion or Li-Poly cell directly without an LDO, and SleepWalking peripherals wake the CPU only when a sensor interrupt fires - critical for multi-day battery life. The integrated USB 2.0 Full-Speed interface also enables charging and firmware update through the same connector.

🔧

Consumer Appliance Control Boards

The ATSAMD21E17A-AU fits consumer appliance control boards (coffee machines, washing machines, HVAC thermostats) because the 48 MHz Cortex-M0+ handles a touch UI, motor PWM via TCC, and a Wi-Fi/BLE companion over UART in a single chip. The 12-channel Event System and DMA controller allow direct peripheral-to-peripheral signalling without CPU wakeup for inverter control loops, while 128 KB Flash stores asset-management tables and OTA upgrade buffers. The 32-TQFP is also widely accepted by appliance CM factories using AOI and selective soldering processes.

🧩

Educational & Maker Development

The ATSAMD21E17A-AU is widely adopted in educational and maker development platforms such as the Arduino Zero and Adafruit Feather M0 because it pairs an Arduino-friendly bootloader ecosystem with USB device support out of the box. The 48 MHz Cortex-M0+ runs the Arduino core, and 128 KB Flash is enough for typical sketches plus libraries for SD cards, displays, and sensors. Datasheet document 40001882A includes a full peripheral-mapping guide, while the Atmel/Microchip Studio IDE supports the SWD interface through the on-board debugger.

Recommended Products Summary

ATSAMR21G18A-MU Integrated Cortex-M0+ MCU + 2.4 GHz radio for wireless sensor hubs Used in: Smart-Home Sensor Hubs MICROCHIP-MCP9808 High-accuracy I2C temperature sensor for environmental sensing Used in: Smart-Home Sensor Hubs ATSAMD21E17A-AU Microchip Technology Used in: Smart-Home Sensor Hubs MICROCHIP-AT42QT1010 Single-key QTouch IC for additional touch inputs Used in: USB HID Input Devices PIC16F720-I/SS Microchip Technology Used in: USB HID Input Devices ATSAMD20E18A-MU Microchip Technology Used in: Industrial Metering & PLC I/O MICROCHIP-MCP2515 External CAN controller for industrial fieldbus Used in: Industrial Metering & PLC I/O AT42QT2120 12-channel QTouch IC for larger keypads Used in: Capacitive Touch User Interfaces PIC16F720-I/ML Microchip Technology Used in: Capacitive Touch User Interfaces MICROCHIP-MCP1700 Low-Iq LDO for backup rail Used in: Battery-Powered Wearables ATSAMD11D14A-MNT Microchip Technology Used in: Battery-Powered Wearables ATSAMW25 SmartConnect Wi-Fi module paired via SERCOM UART Used in: Consumer Appliance Control Boards PIC16F716T-I/SO Microchip Technology Used in: Consumer Appliance Control Boards ATSAMD20-XPRO Microchip Technology Used in: Educational & Maker Development ATSAMD21E18A-AU Same family, 256 KB Flash upgrade for advanced makers Used in: Educational & Maker Development
What is the operating voltage range of the ATSAMD21E17A-AU?
The ATSAMD21E17A-AU operates from 1.62 V to 3.63 V on VDDIN, with a separate VDDIO domain typically tied to the same rail. According to the Microchip SAM D21E datasheet 40001882A, the part can be powered directly from a single 1.8 V, 2.5 V, 3.0 V, or 3.3 V source without an external voltage regulator, simplifying battery-powered designs.
How much Flash and SRAM does the ATSAMD21E17A-AU have?
The ATSAMD21E17A-AU integrates 128 KB of in-system programmable Flash with a 4 KB read-while-write (RWW) region, plus 16 KB of SRAM. The RWW section can be erased and reprogrammed while the rest of the Flash is executing code, enabling over-the-air firmware updates without an external bootloader.
What is the maximum CPU clock speed of the ATSAMD21E17A-AU?
The ATSAMD21E17A-AU runs the ARM Cortex-M0+ core at up to 48 MHz. According to the manufacturer datasheet, this delivers 2.46 CoreMark/MHz - roughly 118 CoreMark - providing enough headroom for USB stacks, sensor fusion, and capacitive touch processing in a single chip.
Does the ATSAMD21E17A-AU include a USB controller?
Yes, the ATSAMD21E17A-AU includes a USB 2.0 Full-Speed (12 Mbps) device interface with an on-chip USB transceiver and 2 KB of dedicated endpoint RAM. The internal 3.3 V USB regulator can be bypassed or used depending on VBUS topology, eliminating the need for an external USB PHY in most HID, CDC, or vendor-class designs.
Where can I download the ATSAMD21E17A-AU datasheet?
The official ATSAMD21E17A-AU datasheet is hosted by Microchip at https://www.microchip.com/content/dam/mchp/documents/OTH/ProductDocuments/DataSheets/40001882A.pdf (document 40001882A). It contains the full electrical characteristics, pinout, peripheral mapping, and ordering information for the entire SAM D21E/G/J family. Distributors such as DigiKey and Mouser also link the same PDF from their ATSAMD21E17A-AU product pages.
What is the pinout of the ATSAMD21E17A-AU?
The ATSAMD21E17A-AU uses a 32-pin TQFP package (7x7 mm, 0.8 mm pitch). Per the datasheet, pin 1 is PA00, pin 16 is GND, pin 17 is VDDIN, pin 18 is VDDIO, and pin 31 is PA30 (SWDIO) with pin 32 being PA31 (SWCLK). Pin 1 is at the top-left with the orientation dot or notch pointing up - see the package diagram on the XAIPART product page for full 32-pin detail.
What is the difference between ATSAMD21E17A-AU and ATSAMD21E16A-AU?
The ATSAMD21E17A-AU has 128 KB Flash and 16 KB SRAM, while the ATSAMD21E16A-AU has 64 KB Flash and 8 KB SRAM. Both share the same 32-pin TQFP, same 48 MHz Cortex-M0+ core, same USB peripheral set, and same SAM D21E pinout - meaning the E17 is a drop-in upgrade for the E16 if you need extra memory.
Can ATSAMD21G18A-AU replace ATSAMD21E17A-AU on the same PCB?
No - the ATSAMD21G18A-AU uses a 48-pin TQFP package while the ATSAMD21E17A-AU uses a 32-pin TQFP. The two are not pin-compatible and cannot be drop-in swapped. Choose ATSAMD21E variants (32-pin) when board space is constrained, or ATSAMD21G variants (48-pin) when you need more I/O lines for the same Cortex-M0+ performance tier.
Is the ATSAMD21E17A-AU RoHS compliant?
Yes, the ATSAMD21E17A-AU is RoHS compliant per Microchip product documentation and all major distributor listings including DigiKey and Mouser. The 'AU' suffix specifically designates a lead-free, green-compound TQFP package, and the same die is also available in automotive AEC-Q100 grade (part numbers ending in -AU-E or with Q1/Q variants on request through Microchip sales).
What is the price of the ATSAMD21E17A-AU?
As of 2026-09-21, the ATSAMD21E17A-AU is priced around USD 4.20 at qty 1, USD 3.35 at qty 100, and USD 2.30 at qty 3000 from authorized distributors such as DigiKey and Mouser. Pricing fluctuates with lead time and demand - check Octopart (octopart.com/part/microchip/ATSAMD21E17A-AU) for live distributor stock and tape-and-reel pricing on the -AUT variant.
What is the lead time for ATSAMD21E17A-AU?
As of 2026-09-21, DigiKey lists the ATSAMD21E17A-AU in stock for immediate shipping, and Mouser reports 9 distributors with available inventory per Octopart. Typical factory lead time for direct Microchip orders is 10-14 weeks for tray quantities, but the -AU suffix is widely stocked through distribution channels.
Where to buy ATSAMD21E17A-AU online?
The ATSAMD21E17A-AU can be purchased online from DigiKey (digikey.com/en/products/detail/microchip-technology/ATSAMD21E17A-AU/4935885), Mouser (mouser.com/ProductDetail/Microchip-Technology/ATSAMD21E17A-AU), and through Octopart (octopart.com/part/microchip/ATSAMD21E17A-AU) which aggregates 9 distributors. For high-volume production, contact Microchip direct sales or authorized franchise distributors.
Is ATSAMD21E17A-AU suitable for low-power IoT sensors?
Yes, the ATSAMD21E17A-AU is well suited for low-power IoT sensors thanks to Idle and Standby sleep modes, SleepWalking peripherals that wake the CPU only on qualified events, and a 32-bit RTC for periodic wake. Pairing it with an external sub-GHz or BLE radio gives a multi-year battery-life node with on-board USB for firmware update and battery charging.
What is the best drop-in replacement for the ATSAMD21E17A-AU?
The best drop-in replacement is ATSAMD21E17A-AUT (tape-and-reel packaging of the same die), followed by ATSAMD21E16A-AU (64 KB Flash / 8 KB SRAM) if you can fit a smaller firmware image. For AEC-Q100 automotive applications, Microchip offers automotive-grade variants within the same SAM D21E 32-pin TQFP family - cross-brand Cortex-M0+ in the same package is uncommon, so same-brand alternatives are strongly preferred.
ATSAMD21E17A-AU vs ATSAMD21E17A-MU - which is better for my design?
The ATSAMD21E17A-AU is a 32-pin TQFP (7x7 mm) while the ATSAMD21E17A-MU is a 32-pin QFN (5x5 mm) with an exposed thermal pad. Choose the AU if your board uses hand-reworkable packages or legacy TQFP footprints; choose the MU for smaller PCB area and better thermal performance at high CPU loads. Both share the same SAM D21E die, peripherals, and 128 KB / 16 KB memory, so firmware is portable between them.

Engineering reference data for ATSAMD21E17A-AU — comparison, design guidance, and compliance information.

Selection Guide

Choose ATSAMD21E17A-AU when you need a 32-pin TQFP Cortex-M0+ MCU with 128 KB Flash, 16 KB SRAM, and integrated USB 2.0 Full-Speed for HID, metering, or smart-home hub designs. Choose ATSAMD21E17A-AUT if you need the same silicon on tape-and-reel for high-volume SMT assembly. Choose ATSAMD21E16A-AU when 64 KB Flash is sufficient (typically basic keyboard firmware, simple sensor nodes), saving roughly 15-25% unit cost. Choose ATSAMD21E15B-AU only for minimal-memory appliances where 32 KB Flash and 4 KB SRAM are enough. All five alternatives share the same 32-TQFP (7x7 mm) footprint, so PCB layout can be reused across the family without rework.

Comparison with Alternatives

Parameter This Product ATSAMD21E17A-AUT ATSAMD21E17A-AF ATSAMD21E16A-AU ATSAMD21E15B-AU ATSAMD21E16B-AU
Package 32-TQFP (7x7 mm) 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same 32-TQFP (7x7 mm) - same
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Flash Memory 128 KB 128 KB 128 KB 64 KB 32 KB 64 KB
SRAM 16 KB 16 KB 16 KB 8 KB 4 KB 8 KB
Maximum CPU Frequency 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz 48 MHz
USB Controller Full-Speed USB 2.0 with on-chip PHY Full-Speed USB 2.0 with on-chip PHY Full-Speed USB 2.0 with on-chip PHY Full-Speed USB 2.0 with on-chip PHY Full-Speed USB 2.0 with on-chip PHY Full-Speed USB 2.0 with on-chip PHY
SERCOM Channels 6 6 6 6 6 6
Operating Voltage 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V 1.62 V to 3.63 V
Carrier Type Tray Tape & Reel Tray Tray Tray Tray

Key Differentiators

  • Largest Flash in the SAM D21E 32-pin TQFP family (vs ATSAMD21E16A-AU)
  • Higher memory tier than ATSAMD21E15B-AU (vs ATSAMD21E15B-AU)
  • Identical silicon to ATSAMD21E17A-AUT (vs ATSAMD21E17A-AUT)

Design Notes

Place a 100 nF X7R ceramic bypass capacitor within 5 mm of every VDDIN/VDDIO pin pair, plus a single 4.7 uF bulk capacitor on the main supply rail. The internal 3.3 V USB regulator requires its own 1 uF capacitor on the VDD33 output pin even when the regulator is bypassed externally - see datasheet document 40001882A section 'Typical Applications'. Avoid routing high-frequency digital signals across the analog AVDD region to preserve ADC SNR above 60 dB at full 350 ksps sampling rate.

Route the USB DP/DM lines as a 90 ohm differential pair with no splits or vias, and place the 27 ohm series termination resistors within 5 mm of the device pads. For capacitive touch via the Peripheral Touch Controller (PTC), use a driven shield layer directly above the sensor electrodes to reject moisture and conducted noise. Add a 4-layer stackup with a continuous ground plane under the QFN/TQFP exposed pad; the 32-TQFP does not have an EPB, so ensure copper pour defines QFN thermal relief even though no pad exists for this package.

Do not exceed 3.63 V on VDDIN or VDDIO - the SAM D21E has no internal 5 V tolerance on GPIO. The RESET pin is active-low and must be pulled up to VDDIO with a 10 kohm resistor plus a 100 nF capacitor to ground for stable boot. When using the integrated USB 2.0 regulator, ensure VBUS rises before or simultaneously with VDDIN, otherwise the device enters an undefined boot state requiring a power cycle. The 32-TQFP does not have an exposed thermal pad, so at 48 MHz full load expect roughly 8-12 mA active current without any thermal derating needed.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and lead-free per Microchip product page. Standard industrial grade (-40 C to +85 C); for AEC-Q100 automotive applications contact Microchip sales for the automotive-grade SAM D21E variant (separate part number).

Data verified on: 2026-09-21 — data verified and curated by XAIPART's component engineering team

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