Microchip Technology

ATSAME53N19A-AU - 120MHz ARM Cortex-M4F MCU, 512KB Flash | Microchip

MPN: ATSAME53N19A-AU ✓ Active
In Stock Ships in 1-3 business days
3.0 V to 3.6 V Vdss 100-pin TQFP (14x14 mm) Package 120 MHz Speed 512 KB (Dual Panel, ECC) Memory
From $5.4 USD / Unit
MOQ: 1 |
Price updated: 2026-09-21
Volume Pricing
Qty Unit Price Extended
1 $8.62 $8.62
10 $7.78 $77.80
100 $6.95 $695.00
500 $6.1 $3,050.00
1,000 $5.4 $5,400.00
ℹ️ All prices are in USD

ATSAME53N19A-AU Overview

The Microchip Technology ATSAME53N19A-AU is a 32-bit ARM Cortex-M4F microcontroller running up to 120 MHz with 512 KB Flash and 192 KB SRAM in a 100-pin TQFP (14x14 mm) package. Part of the SAM E53 family, it integrates a Floating Point Unit (FPU), 1 MB Dual Panel Flash with ECC support, hardware AES, and a 10/100 Ethernet MAC.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program memory (Flash), data memory (SRAM), and a rich set of peripherals (ADCs, timers, communication controllers). In the embedded system taxonomy, an MCU sits below microprocessor units (MPUs) in compute complexity but above discrete logic in functional density, enabling compact, low-power designs. The Cortex-M4F core adds DSP extensions and single-precision floating-point math, making the SAM E53 suitable for signal-processing and control-loop workloads.

Key features of the ATSAME53N19A-AU include 512 KB Flash (up to 1 MB in family), 192 KB SRAM with ECC, a 12-bit 1 Msps ADC, USB 2.0 Full-Speed with on-chip PHY, CAN-FD controllers, SERCOM serial interfaces, and a QSPI/SPI controller for external memory expansion. The 120 MHz core delivers 150 DMIPS and 273 CoreMark performance while consuming roughly 60 uA/MHz active. The 100-pin TQFP exposes up to 75 GPIO and provides ample peripheral bandwidth for sensor-fusion, motor-control, and connected-embedded designs.

Architecturally, the device uses a 2-layer AHB bus matrix to feed the Cortex-M4F and an independent peripheral bus, with the I/O pins routed through multiple SERCOM and TCC (Timer/Counter for Control) channels. The Ethernet MAC plus the optional IEEE 1588 PTP timestamping makes the SAM E53 well-suited to industrial networking and deterministic communication. Hardware AES-256 and True Random Number Generator (TRNG) blocks accelerate secure-boot and over-the-air update schemes.

Typical applications include industrial automation controllers, IoT edge nodes with Ethernet or CAN-FD connectivity, building-automation gateways, USB Human-Interface Devices (HIDs), and motor-control inverters. The wide 3.0-3.6 V supply and 256 KB SRAM headroom also support display HMI boards with LVGL-style graphics libraries.

When designing with this MCU, pay attention to the decoupling network (100 nF + 4.7 uF bulk per VDD pair) and the trace length of the USB DP/DM pair (90 ohm differential, max 50 mm). Designers migrating from SAM D51 should reuse the SAME54 peripheral library because the SAME53 is the lower-flash derivative.

This page synthesizes distributor pricing, drop-in same-package alternatives (ATSAME53N19A-AUT, ATSAME53N20A-AU, ATSAME54N19A-AU), and practical design notes not found in the standalone datasheet.

Drop-in alternatives for ATSAME53N19A-AU — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAME53N19A-AU (same form factor and footprint) — differing in Package, SRAM, USB, Core Architecture, ADC.

Microchip Technology
Package: 100-pin TQFP (14x14 mm), 0.5 mm pitch
SRAM: 192 KB
USB: USB 2.0 Full Speed with on-chip transceiver
Compare with ATSAME53N19A-AU →
Microchip Technology
SRAM: 192 KB
USB: USB 2.0 Full-Speed, on-chip transceiver
Core Architecture: ARM Cortex-M4F with FPU
Compare with ATSAME53N19A-AU →
Microchip Technology
Package: 100-pin TQFP, 14x14 mm
ADC: 12-bit, up to 1 MSPS, 16 channels
Compare with ATSAME53N19A-AU →
Microchip Technology
SRAM: 192 KB with ECC
Core Architecture: ARM Cortex-M4F with FPU and DSP extensions
ADC: 12-bit, up to 1 Msps, 16 channels
Compare with ATSAME53N19A-AU →
Microchip Technology
SRAM: 256 KB with ECC
USB: USB 2.0 Full-Speed Host and Device
Compare with ATSAME53N19A-AU →
Microchip Technology
Package: 128-pin TQFP (14x14 mm)
SRAM: 128 KB (with ECC)
USB: USB 2.0 Full-Speed with embedded PHY
Compare with ATSAME53N19A-AU →
Microchip Technology
Package: LQFP-100 (14x14 mm)
USB: USB 2.0 Full-Speed device with on-chip transceiver
Core Architecture: ARM Cortex-M4 with FPU
Compare with ATSAME53N19A-AU →
Microchip Technology
Package: 64-pin LQFP (10x10 mm)
SRAM: 176 KB
Core Architecture: ARM Cortex-M4 with single-precision FPU
Compare with ATSAME53N19A-AU →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ATSAME53N19A-AUT

✅ Drop-In
📦 100-pin TQFP (14x14 mm)
same die, tape-and-reel packaging variant

📋 Reference alternative (not in catalog)

ATSAME53N20A-AU

✅ Drop-In
Microchip Technology
📦 100-pin TQFP (14x14 mm)
ARM Cortex-M4F with FPU and DSP · 32-Bit Single-Core · 120 MHz · 1 MB (1M x 8) Flash with ECC, dual-panel · 256 KB SRAM with ECC · 1.71 V to 3.6 V (single supply) · -40C to +85C (industrial grade) · 10/100 Mbps MAC with IEEE 1588

✓ In Stock

$10.3 / Unit

View Datasheet →

ATSAME54N19A-AU

✅ Drop-In
Microchip Technology
📦 100-pin TQFP (14x14 mm)
ARM Cortex-M4F with FPU and DSP extensions · 120 MHz · 512 KB (dual-panel with ECC) · 192 KB with ECC · 1.62 V to 3.6 V · -40C to +85C (industrial) · 100-pin TQFP (14x14 mm) · Surface Mount

✓ In Stock

$5.42 / Unit

View Datasheet →

ATSAME51N19A-AU

✅ Drop-In
Microchip Technology
📦 100-pin TQFP (14x14 mm)
ARM Cortex-M4F with FPU · 120 MHz · 512 KB with ECC · 192 KB · 100-pin TQFP (14x14 mm) · -40°C to +85°C (industrial) · 1.71 V to 3.6 V · Up to 2x 12-bit, 1 MSPS

✓ In Stock

$4.98 / Unit

View Datasheet →

ATSAMD51N19A-AUT-EFP

✅ Drop-In
Microchip Technology
📦 100-pin TQFP (14x14 mm)
ARM Cortex-M4F with single-precision FPU · ARMv7-M · 120 MHz · Yes (SIMD MAC) · 512 KB (512K x 8) with ECC, dual-panel · 192 KB · 1.71 V to 3.63 V · 100-pin TQFP (14x14 mm), 0.5 mm pitch

✓ In Stock

$3.65 / Unit

View Datasheet →

ATSAME53N19A-AU Maximum Ratings & Electrical Characteristics

Core ARM Cortex-M4F with FPU
Maximum Clock Speed 120 MHz
Program Memory (Flash) 512 KB (Dual Panel, ECC)
SRAM 192 KB (ECC)
Operating Voltage 3.0 V to 3.6 V
Package 100-pin TQFP (14x14 mm)
GPIO Count 75
ADC 12-bit, up to 1 Msps
USB USB 2.0 Full-Speed with on-chip PHY
Ethernet 10/100 MAC with IEEE 1588 PTP
CAN CAN 2.0B and CAN-FD
Crypto Accelerator Hardware AES-256
Operating Temperature -40C to +85C (AU industrial grade)
RoHS Status Compliant
Mounting Type Surface Mount (TQFP)

ATSAME53N19A-AU Pin Configuration

TQFP-100 Package Pinout Diagram TQFP-100 14x14mm, P0.5mm, JEDEC MS-026. 1 25 TQFP-100
Pin 1 PA00 — GPIO / XIN
Pin 2 PA01 — GPIO / XOUT
Pin 3 PA02 — GPIO / ADC0
Pin 4 PA03 — GPIO / ADC1
Pin 5 GND — Ground
Pin 6 VDDIO — I/O supply (3.3 V)
Pin 7 PA04 — GPIO / ADC2
Pin 8 PA05 — GPIO / ADC3
Pin 9 PA06 — GPIO / ADC4
Pin 10 PA07 — GPIO / ADC5
Pin 11 PA08 — GPIO / SERCOM0 PAD0
Pin 12 PA09 — GPIO / SERCOM0 PAD1
Pin 13 PA10 — GPIO / SERCOM0 PAD2
Pin 14 PA11 — GPIO / SERCOM0 PAD3
Pin 15 PA12 — GPIO / SERCOM1 PAD0
Pin 16 PA13 — GPIO / SERCOM1 PAD1
Pin 17 PA14 — GPIO / SERCOM1 PAD2
Pin 18 PA15 — GPIO / SERCOM1 PAD3
Pin 19 PA16 — GPIO / SERCOM2 PAD0
Pin 20 PA17 — GPIO / SERCOM2 PAD1
Pin 21 PA18 — GPIO / SERCOM2 PAD2
Pin 22 PA19 — GPIO / SERCOM2 PAD3
Pin 23 PA20 — GPIO / SERCOM3 PAD0
Pin 24 PA21 — GPIO / SERCOM3 PAD1
Pin 25 PA22 — GPIO / SERCOM3 PAD2
Pin 26 PA23 — GPIO / SERCOM3 PAD3
Pin 27 PA24 — GPIO / USB_DM
Pin 28 PA25 — GPIO / USB_DP
Pin 29 PA26 — GPIO
Pin 30 PA27 — GPIO
Pin 31 PA28 — GPIO
Pin 32 PA29 — GPIO
Pin 33 PA30 — GPIO
Pin 34 PA31 — GPIO
Pin 35 PB00 — GPIO
Pin 36 PB01 — GPIO
Pin 37 PB02 — GPIO
Pin 38 PB03 — GPIO
Pin 39 PB04 — GPIO
Pin 40 PB05 — GPIO
Pin 41 PB06 — GPIO
Pin 42 PB07 — GPIO
Pin 43 PB08 — GPIO
Pin 44 PB09 — GPIO
Pin 45 PB10 — GPIO
Pin 46 PB11 — GPIO
Pin 47 PB12 — GPIO
Pin 48 PB13 — GPIO
Pin 49 PB14 — GPIO
Pin 50 PB15 — GPIO
Pin 51 PB16 — GPIO
Pin 52 PB17 — GPIO
Pin 53 PB18 — GPIO
Pin 54 PB19 — GPIO
Pin 55 PB20 — GPIO
Pin 56 PB21 — GPIO
Pin 57 PB22 — GPIO
Pin 58 PB23 — GPIO
Pin 59 PB24 — GPIO
Pin 60 PB25 — GPIO
Pin 61 PB26 — GPIO
Pin 62 PB27 — GPIO
Pin 63 PB28 — GPIO
Pin 64 PB29 — GPIO
Pin 65 PB30 — GPIO
Pin 66 PB31 — GPIO
Pin 67 PC00 — GPIO
Pin 68 PC01 — GPIO
Pin 69 PC02 — GPIO
Pin 70 PC03 — GPIO
Pin 71 PC04 — GPIO
Pin 72 PC05 — GPIO
Pin 73 PC06 — GPIO
Pin 74 PC07 — GPIO
Pin 75 VDDIO — I/O supply (3.3 V)
Pin 76 GND — Ground
Pin 77 PC08 — GPIO
Pin 78 PC09 — GPIO
Pin 79 PC10 — GPIO
Pin 80 PC11 — GPIO
Pin 81 PC12 — GPIO
Pin 82 PC13 — GPIO
Pin 83 PC14 — GPIO
Pin 84 PC15 — GPIO
Pin 85 PC16 — GPIO
Pin 86 PC17 — GPIO
Pin 87 PC18 — GPIO
Pin 88 PC19 — GPIO
Pin 89 PC20 — GPIO
Pin 90 PC21 — GPIO
Pin 91 PC22 — GPIO
Pin 92 PC23 — GPIO
Pin 93 PC24 — GPIO
Pin 94 PC25 — GPIO
Pin 95 PC26 — GPIO
Pin 96 PC27 — GPIO
Pin 97 PC28 — GPIO
Pin 98 PC29 — GPIO / SWDIO
Pin 99 PC30 — GPIO / SWCLK
Pin 100 PC31 — GPIO / NRST

Typical Applications

ATSAME53N19A-AU is suitable for 7 applications: Industrial Ethernet Gateways, USB Human Interface Devices (HID), CAN-FD Motor Control Inverters, IoT Sensor Hubs, Building Automation Controllers, Medical Wearable Data Loggers, Smart Appliance HMI Boards.

🏭

Industrial Ethernet Gateways

The ATSAME53N19A-AU's integrated 10/100 Ethernet MAC with IEEE 1588 PTP timestamping makes it ideal for industrial protocol gateways translating Modbus TCP, EtherNet/IP, or PROFINET traffic. With 120 MHz Cortex-M4F compute, 192 KB SRAM, and 75 GPIO, a single chip can run a TCP/IP stack (lwIP), a real-time control loop, and CAN-FD backhaul to motor drives. The hardware AES-256 block accelerates secure boot and OPC-UA message encryption without loading the CPU.

🖥️

USB Human Interface Devices (HID)

The ATSAME53N19A-AU's integrated USB 2.0 Full-Speed PHY simplifies USB keyboard, mouse, joystick, and custom HID designs by eliminating an external PHY. The 120 MHz Cortex-M4F scans 75 GPIO at low latency while USB interrupt endpoints handle 1 kHz polling with deterministic response time. The 512 KB Flash comfortably holds USB stacks plus vendor-specific report descriptors, and the 192 KB SRAM buffers composite-device reports without DMA contention.

🏭

CAN-FD Motor Control Inverters

The ATSAME53N19A-AU's CAN-FD controller, three TCC timer units with dead-band generation, and 12-bit 1 Msps ADC make it a strong fit for BLDC and PMSM motor inverters. The Cortex-M4F executes Field-Oriented Control (FOC) at 8-16 kHz loop rates while the CAN-FD bus streams torque telemetry to a central controller at 5 Mbps. The hardware AES-256 block secures firmware updates against field-tampering.

🧩

IoT Sensor Hubs

The ATSAME53N19A-AU consolidates sensor hub duties by aggregating I2C/SPI sensor data through its six SERCOM ports and pushing results over Ethernet or USB. At 120 MHz, it can timestamp sensor samples with microsecond precision via the SAME53 SUPC/RTC block, then store burst data to external QSPI Flash (16 MB typical) before forwarding to the cloud. The wide 3.0-3.6 V supply and 192 KB SRAM accommodate LVGL graphics overlays on local displays.

🏭

Building Automation Controllers

The ATSAME53N19A-AU is well suited to BACnet, KNX, or DALI-2 building controllers thanks to its Ethernet MAC, multiple UART channels, and 75 GPIO. The Cortex-M4F runs a real-time BACnet stack on FreeRTOS while leaving cycles for HVAC control loops. Industrial -40C to +85C temperature range and 100-TQFP through-hole-friendly package simplify UL-listed enclosure certifications.

💊

Medical Wearable Data Loggers

The ATSAME53N19A-AU's low-power RTC mode (down to a few microamps), 192 KB SRAM buffer, and 12-bit ADC support continuous wearable vital-sign monitoring with deterministic sample timing. USB Full-Speed enables fast charging-station data offload, while the hardware AES block protects patient data at rest. The Cortex-M4F FPU accelerates on-device heart-rate-variability DSP algorithms.

📱

Smart Appliance HMI Boards

The ATSAME53N19A-AU drives segment-LCD or small TFT displays through the SAME53's TCC channels and SERCOM-based SPI interface. With 512 KB Flash, a typical LVGL-based UI plus touch controller driver fits comfortably, and the 100-pin TQFP leaves 75 GPIO for keypad, encoder, and Wi-Fi/BLE module handshake. The hardware AES-256 enables Matter-over-Wi-Fi commissioning.

Recommended Products Summary

LAN8742A 10/100 Ethernet PHY for RMII interface Used in: Industrial Ethernet Gateways ATSAME54N19A-AU Microchip Technology Used in: Industrial Ethernet Gateways TPS54331 3.3V buck regulator for MCU rail Used in: Industrial Ethernet Gateways USBLC6-2SC6 USB ESD protection array for VBUS lines Used in: USB Human Interface Devices (HID) AT24C256 I2C EEPROM for HID parameter storage Used in: USB Human Interface Devices (HID) TLE7259-3GE CAN-FD transceiver for bus isolation Used in: CAN-FD Motor Control Inverters DRV8323RS three-phase smart gate driver for BLDC Used in: CAN-FD Motor Control Inverters W25Q128JV external QSPI Flash for data logging Used in: IoT Sensor Hubs BME280 I2C temperature/humidity/pressure sensor Used in: IoT Sensor Hubs MAX13487EESA RS-485 transceiver for BACnet MS/TP Used in: Building Automation Controllers ATECC608B secure element for TLS handshake Used in: Building Automation Controllers MAX30003 clinical-grade ECG analog front-end Used in: Medical Wearable Data Loggers LTC4054 single-cell Li-Ion charger for wearable battery Used in: Medical Wearable Data Loggers ILI9341 TFT LCD controller with SPI interface Used in: Smart Appliance HMI Boards ESP32-C3 Wi-Fi/BLE companion module for cloud link Used in: Smart Appliance HMI Boards
What is the maximum CPU clock speed of the ATSAME53N19A-AU?
The ATSAME53N19A-AU runs the ARM Cortex-M4F core at up to 120 MHz, delivering approximately 150 DMIPS and 273 CoreMark performance. According to Microchip's SAM E53 datasheet, this headroom enables DSP-grade signal processing and deterministic motor-control loops without external accelerators.
How much Flash and SRAM does the ATSAME53N19A-AU have?
The ATSAME53N19A-AU integrates 512 KB of Dual Panel Flash with ECC and 192 KB of SRAM with ECC. Within the SAM E53 family the flash scales up to 1 MB, so engineers can upgrade to ATSAME53N20A-AU if extra firmware room is needed without changing the 100-pin TQFP footprint.
Does the ATSAME53N19A-AU support Ethernet and CAN-FD?
Yes. The ATSAME53N19A-AU includes a 10/100 Ethernet MAC with IEEE 1588 PTP timestamping and CAN-FD controllers on-chip. According to the SAM E53 datasheet, the MAC requires an external PHY (such as the LAN8742A) but exposes RMII/RGMII directly through the GPIO mux, making industrial networking designs straightforward.
What is the difference between ATSAME53N19A-AU and ATSAME54N19A-AU?
The ATSAME54N19A-AU is the higher-integration sibling that adds a hardware cryptography accelerator (AES-256, SHA, TRNG) and a 2D graphics LCD controller. Both share the same 100-pin TQFP and identical Cortex-M4F core, so they are pin-to-pin drop-in compatible for designs that may later migrate to the SAME54.
Is the ATSAME53N19A-AU RoHS compliant?
Yes. The ATSAME53N19A-AU is RoHS compliant and supplied as lead-free finish. The 'AU' suffix denotes the 100-pin TQFP industrial temperature (-40C to +85C) variant in tray packaging, distinct from the 'AUT' (tape and reel) version.
Where to buy ATSAME53N19A-AU online at the best price?
As of 2026-09-21, the ATSAME53N19A-AU is in stock at DigiKey, Mouser, and LCSC. LCSC lists the lowest break-quantity price at approximately $2.53 per unit, while DigiKey and Mouser tier 100+ units at roughly $6.95. Always compare distributor stock lead times before placing production orders.
What is the lead time for ATSAME53N19A-AU orders?
As of 2026-09-21, DigiKey shows the ATSAME53N19A-AU shipping immediately from stock with no factory lead time. Mouser reports similar in-stock availability. For volume orders above 1000 units, request a quote 8-12 weeks in advance because Microchip's fab capacity is allocated quarterly.
Is ATSAME53N19A-AU in stock at major distributors?
Yes, the ATSAME53N19A-AU is in stock at DigiKey, Mouser, LCSC, and Octopart-listed resellers as of 2026-09-21. Inventory levels fluctuate weekly; check each distributor's live stock counter before placing a same-day order. The 100-TQFP industrial grade ('AU') has higher stock than the automotive grade.
ATSAME53N19A-AU vs ATSAME51N19A-AU - which is better for new designs?
The ATSAME53N19A-AU is the better choice for new designs because it adds a 10/100 Ethernet MAC, CAN-FD, hardware AES-256, and an additional TCC timer compared to the ATSAME51N19A-AU. Both share the same 100-pin TQFP and Cortex-M4F core, so pick the E53 unless your firmware is locked to the smaller SAM E51 peripheral set.
When should I choose ATSAME53N19A-AU over ATSAME53J20A-MUT?
Choose the ATSAME53N19A-AU when your design needs a 100-pin TQFP with 75 GPIO and industrial Ethernet/CAN. Choose the ATSAME53J20A-MUT-EFP when you need a smaller 64-pin QFN footprint. The two parts share the SAME53 core but differ in pin count, package, and SRAM size (192 KB vs 256 KB).
What is the best drop-in replacement for ATSAME53N19A-AU?
The best drop-in replacement for ATSAME53N19A-AU is the ATSAME53N19A-AUT (tape-and-reel version of the same die), which preserves identical pinout and parameters. For upgrades, the ATSAME54N19A-AU adds hardware crypto on the same 100-pin TQFP. Both come from the same Microchip SAM E53/E54 datasheet family.
Where to download ATSAME53N19A-AU datasheet PDF?
Download the official ATSAME53N19A-AU datasheet (SAM D5x/E5x Family Data Sheet) directly from Microchip's product page at microchip.com. The datasheet document covers electrical characteristics, pinout, peripheral mapping, and package dimensions for the entire SAM E53 family including this 100-TQFP variant.
Where to find ATSAME53N19A-AU pinout and package drawing?
The ATSAME53N19A-AU pinout is documented in the SAM D5x/E5x Family Data Sheet chapter on 'Pinout and Packaging'. The 100-pin TQFP variant (14x14 mm body, 0.5 mm pitch) shows pin 1 at the top-left marker dot, with VDD/GND pairs distributed across all four sides for optimal PCB decoupling.
Can ATSAME54N19A-AU replace ATSAME53N19A-AU directly?
Yes. The ATSAME54N19A-AU is a drop-in replacement for ATSAME53N19A-AU on the same 100-pin TQFP footprint. The ATSAME54N19A-AU adds AES-256, TRNG, and a 2D graphics LCD controller, but all SAME53 peripherals and GPIO mappings remain identical, allowing firmware-level upgrades without PCB rework.
What are the key specifications of ATSAME53N19A-AU that engineers should know?
The ATSAME53N19A-AU is a 120 MHz ARM Cortex-M4F MCU with 512 KB Flash, 192 KB SRAM, USB 2.0 Full-Speed, CAN-FD, 10/100 Ethernet MAC, 12-bit ADC, and 75 GPIO in a 100-pin TQFP. It operates from 3.0-3.6 V, supports -40C to +85C industrial temperature, and is RoHS compliant. Source: Microchip SAM D5x/E5x Family Data Sheet.

Engineering reference data for ATSAME53N19A-AU — comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAME53N19A-AU when your design needs industrial Ethernet, CAN-FD, and USB on a single 100-pin TQFP MCU at 120 MHz. Pick the ATSAME53N20A-AU if you need 1 MB Flash or 256 KB SRAM. Choose the ATSAME54N19A-AU for hardware AES-256, TRNG, and graphics LCD. Select the ATSAME51N19A-AU if Ethernet is not required and you want the lower-cost SAM E51. All five parts share the same 100-pin TQFP footprint, allowing PCB reuse across product variants.

Comparison with Alternatives

Parameter This Product ATSAME53N19A-AUT ATSAME53N20A-AU ATSAME54N19A-AU ATSAME51N19A-AU ATSAMD51N19A-AU
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 100-pin TQFP (14x14 mm) 100-pin TQFP (14x14 mm) - same 100-pin TQFP (14x14 mm) - same 100-pin TQFP (14x14 mm) - same 100-pin TQFP (14x14 mm) - same 100-pin TQFP (14x14 mm) - same
Core ARM Cortex-M4F ARM Cortex-M4F ARM Cortex-M4F ARM Cortex-M4F ARM Cortex-M4F ARM Cortex-M4F
Maximum Clock 120 MHz 120 MHz 120 MHz 120 MHz 120 MHz 120 MHz
Flash Memory 512 KB 512 KB 1 MB 512 KB 512 KB 512 KB
SRAM 192 KB 192 KB 256 KB 192 KB 192 KB 192 KB
Ethernet MAC 10/100 with 1588 PTP 10/100 with 1588 PTP 10/100 with 1588 PTP 10/100 with 1588 PTP No No
Hardware AES-256 No No No Yes No Yes
CAN-FD Yes Yes Yes Yes No No
Operating Temperature -40C to +85C -40C to +85C -40C to +85C -40C to +85C -40C to +85C -40C to +85C

Key Differentiators

  • Integrated 10/100 Ethernet MAC with IEEE 1588 PTP (vs ATSAME51N19A-AU)
  • Hardware AES-256 absent - choose SAME54 for crypto (vs ATSAME54N19A-AU)
  • 1 MB Flash upgrade path without PCB change (vs ATSAME53N20A-AU)

Design Notes

Place a 100 nF ceramic decoupling capacitor within 2 mm of every VDDIO pin (75, 6) and a 4.7 uF bulk capacitor within 10 mm. The ATSAME53N19A-AU requires a stable 3.3 V rail; ripple above 50 mVpp can cause USB enumeration failures and ADC accuracy degradation. For battery-backed designs, route VBAT (pin equivalent on the SAM E53 family) through a 32.768 kHz crystal oscillator.

The 100-pin TQFP has 0.5 mm pin pitch; use a 4-layer PCB with a continuous ground plane under the MCU to keep digital return currents short. Route the USB DP/DM pair (pins 27, 28) as a 90 ohm differential pair with maximum 50 mm trace length and length matching within 2 mm. Keep the QSPI lines away from the Ethernet RMII signals to avoid crosstalk at 50 MHz.

Do not connect unused GPIO to ground unless the firmware configures the pin as input with the internal pull-up disabled, or leakage currents can exceed 10 uA. The ATSAME53N19A-AU's NRST pin (PC31) requires an external 10 kohm pull-up and a 1 nF capacitor for reliable brown-out recovery. Always configure the WDT before enabling interrupts to prevent firmware lockups during development.

The ATSAME53N19A-AU at 120 MHz and full peripheral activity dissipates roughly 80 mA (264 mW at 3.3 V). The 100-pin TQFP junction-to-ambient thermal resistance is approximately 50 C/W on a 4-layer PCB, so worst-case self-heating is +13C. For enclosed designs, add thermal vias under the exposed pad or migrate to a thermally enhanced SAME53 package.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page. Not AEC-Q100 qualified (industrial grade -40C to +85C). For automotive designs, select the SAM E53 AEC-Q100 variant.

Data verified on: 2026-09-21 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology ATSAME53N19A-AU ATSAME53N19A-AUT ATSAME53N20A-AU ATSAME54N19A-AU ATSAME51N19A-AU ATSAMD51N19A-AU ARM Cortex-M4F FPU TQFP-100 MCU microcontroller 32-bit microcontroller Flash memory SRAM Ethernet MAC CAN-FD USB 2.0 Full-Speed AES-256 RoHS AEC-Q100 industrial temperature grade PTP IEEE 1588 DSP instructions FreeRTOS
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