P64706-B21 - 32GB DDR5-5600 2Rx8 ECC RDIMM | HPE SmartMemory
MPN: P64706-B21 ✓ Active| Qty | Unit Price | Extended |
|---|---|---|
| 1 | $379 | $379.00 |
| 10 | $365 | $3,650.00 |
| 50 | $349 | $17,450.00 |
| 100 | $329 | $32,900.00 |
| 500 | $305 | $152,500.00 |
P64706-B21 Overview
DDR5 RDIMM (Registered DIMM) is a server-class memory module that places a register buffer between the DRAM chips and the memory controller, reducing electrical loading and enabling higher capacity and speed than unbuffered modules. Within the hierarchy: DDR5 SDRAM -> RDIMM -> ECC Registered DIMM -> Server Memory. DDR5 introduces on-die voltage regulation (PMIC), decision feedback equalization (DFE), and higher bank group counts compared with DDR4, which is essential for bandwidth-bound workloads like in-memory databases, virtualization, and AI inference.
Key features include 32GB module capacity in a single-rank-pair (2Rx8) layout, 5600 MT/s data rate, CL46 CAS latency (46-45-45), 1.10V low-voltage operation (versus 1.2V for DDR4), on-module ECC and parity, and HPE SmartMemory firmware that enables performance optimization, pre-failure alerting, and tighter integration with HPE iLO management. The 288-pin RDIMM form factor is standard for Gen11 platforms.
The module is qualified, tested, and warranty-supported exclusively when deployed in supported HPE ProLiant Gen11 servers (e.g., DL380 Gen11, ML110 Gen11, DL110 Gen11). It uses advanced ECC and Chipkill-like protection mechanisms and integrates with HPE's Smart Memory authentication, which validates genuine HPE firmware during POST and refuses unauthorized modules.
Typical applications include HPE ProLiant Gen11 server memory expansion, virtualization hosts running VMware vSphere or Hyper-V, in-memory databases (SAP HANA, Redis), AI/ML training and inference servers, and enterprise database workloads (Microsoft SQL Server, Oracle). The 32GB density is the sweet-spot upgrade tier for systems scaling from 16GB base configurations to 64GB/96GB populated memory topologies.
When designing with this module, confirm your server's memory population rules (HPE Gen11 requires balanced population across channels for optimal bandwidth) and verify the BIOS supports 5600 MT/s - lower-speed SKUs are used in older Gen10 platforms. Mixing RDIMM speeds is supported but the bus will downclock to the slowest module.
This page synthesizes distributor pricing, OEM equivalent modules, and practical compatibility notes not found in the manufacturer datasheet alone - useful for procurement and IT planners evaluating HPE SmartMemory upgrades.
Drop-in alternatives for P64706-B21 — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.
Quick Comparison Tool — Select alternative parts for side-by-side comparison:
P64706-K21
✅ Drop-In📋 Reference alternative (not in catalog)
P68074-001
✅ Drop-In📋 Reference alternative (not in catalog)
P65254-001
✅ Drop-In📋 Reference alternative (not in catalog)
HMCG88AGBRA191N
✅ Drop-In📋 Reference alternative (not in catalog)
P64706-B21-BN
✅ Drop-In📋 Reference alternative (not in catalog)
TWINRAM-P64706-EQ
✅ Drop-In📋 Reference alternative (not in catalog)
P64706-B21 Maximum Ratings & Electrical Characteristics
| Memory Type | DDR5 SDRAM (RDIMM) |
| Module Capacity | 32 GB (1 x 32 GB) |
| Speed Grade | DDR5-5600 (PC5-44800) |
| Data Rate | 5600 MT/s |
| CAS Latency (CL) | 46 |
| Timings | 46-45-45 |
| Rank Configuration | Dual Rank x8 (2Rx8) |
| Error Correction | ECC (Registered, EC8 grade) |
| Operating Voltage | 1.10 V |
| Form Factor | 288-pin RDIMM |
| Module Type | Registered DIMM (RDIMM) with PMIC |
| Platform Compatibility | HPE ProLiant Gen11 Servers |
| SmartMemory Authentication | Yes (HPE firmware validation) |
| Operating Temperature | 0C to +85C (server ambient) |
| RoHS Status | Compliant |
| Lead-Free | Yes |
| Warranty | Lifetime (when deployed in supported HPE servers) |
P64706-B21 standard Pin Configuration Guide
Pin configuration for P64706-B21 (standard package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.
No detailed pinout data available for P64706-B21.
Refer to the datasheet for full pin configuration.
Typical Applications
P64706-B21 is suitable for 7 applications: HPE ProLiant DL380 Gen11 Memory Expansion, HPE ProLiant ML110 Gen11 Server Memory, Virtualization Hosts (VMware vSphere / Hyper-V), In-Memory Database Servers (SAP HANA / Redis Enterprise), AI/ML Inference and Training Servers, Enterprise Database (Microsoft SQL Server / Oracle), Cloud and Edge Computing Infrastructure.
HPE ProLiant DL380 Gen11 Memory Expansion
The HPE P64706-B21 32GB DDR5-5600 2Rx8 ECC RDIMM is the canonical memory upgrade for HPE ProLiant DL380 Gen11 rack servers. With 32 DIMM slots (16 per CPU in dual-processor configs) and a balanced memory architecture, twelve P64706-B21 modules deliver 384GB total capacity, ideal for SAP HANA scale-up, large SQL Server buffers, and VMware vSphere 8 hosts running 80+ VMs. The 5600 MT/s bandwidth (versus DDR4-2933 in Gen10) gives ~90% higher peak throughput per channel, reducing memory-bound latency in OLTP and analytics workloads.
Recommended
HPE ProLiant ML110 Gen11 Server Memory
The P64706-B21 module upgrades HPE ProLiant ML110 Gen11 tower servers used in SMB and remote-office deployments. ML110 Gen11 supports 16 DIMM slots (8 per CPU); four P64706-B21 modules deliver 128GB, suitable for Microsoft Active Directory, file/print, and small virtualization workloads. The 1.10V DDR5 operation reduces power by ~20% versus DDR4 RDIMMs at equivalent capacity, lowering total cost of ownership in always-on edge environments where thermal and energy budgets are constrained.
Recommended
Virtualization Hosts (VMware vSphere / Hyper-V)
Deploy P64706-B21 modules in HPE Gen11 servers running VMware vSphere 8, Microsoft Hyper-V, or Nutanix AHV hypervisor clusters. Each 32GB module supports roughly 8-12 medium-sized VMs (4 vCPU / 8GB vRAM each), making a 12-module configuration ideal for ~100 VM density. DDR5-5600's higher bandwidth reduces vMotion live-migration time and improves storage I/O latency. ECC RDIMM protection is essential for hypervisor memory overcommit safety, preventing silent data corruption in shared tenant workloads.
Recommended
In-Memory Database Servers (SAP HANA / Redis Enterprise)
P64706-B21 modules scale HPE ProLiant Gen11 servers for SAP HANA, Redis Enterprise, or Apache Ignite in-memory databases where dataset size directly dictates RAM capacity. A fully populated DL380 Gen11 (24 modules) reaches 768GB, suitable for S/4HANA sandbox or mid-size OLTP deployments. The 2Rx8 dual-rank configuration maximizes per-channel rank interleaving, improving random-access latency by ~15% versus single-rank equivalents - critical for hash-lookup-heavy database workloads running at sub-millisecond response targets.
Recommended
AI/ML Inference and Training Servers
P64706-B21 enables HPE ProLiant Gen11 servers to host AI inference and small-model training workloads (PyTorch, ONNX Runtime). 32GB modules paired with NVIDIA L4 or L40S GPUs provide adequate CPU-side memory for preprocessing pipelines and embedding tables. While not the largest density available, 5600 MT/s DDR5 bandwidth keeps the CPU-to-GPU PCIe 5.0 x16 link saturated, which is the typical bottleneck for inference servers running real-time NLP or computer vision at 30+ inferences/second per GPU.
Recommended
Enterprise Database (Microsoft SQL Server / Oracle)
P64706-B21 modules in HPE Gen11 servers deliver the memory footprint required for Microsoft SQL Server 2022 buffer pool extensions, Oracle Database 19c SGA, and PostgreSQL shared_buffers configurations. A 192GB configuration (6 modules) supports ~150GB buffer pool plus OS overhead, enabling mid-size OLTP databases (~5,000 TPS) and BI/reporting workloads. DDR5-5600's 72GB/s theoretical peak per channel minimizes page-fault latency, which directly determines SQL query response time under heavy concurrent load.
Recommended
Cloud and Edge Computing Infrastructure
P64706-B21 modules support edge-cloud workloads on HPE ProLiant Gen11 platforms deployed at remote sites, micro-datacenters, and 5G MEC nodes. The 1.10V DDR5 operation reduces heat output by ~20% versus DDR4, simplifying sealed-edge chassis cooling. SmartMemory firmware provides predictive failure alerts through HPE iLO, allowing remote IT teams to schedule replacement DIMMs before unplanned downtime - critical for unmanned edge sites where technician dispatch costs dominate total TCO.
Recommended
Recommended Products Summary
Engineering reference data for P64706-B21 — comparison, design guidance, and compliance information.
Selection Guide
Comparison with Alternatives
| Parameter | This Product | P64706-K21 | P68074-001 | P65254-001 | HMCG88AGBRA191N | P64706-B21-BN | TWINRAM-P64706-EQ |
|---|---|---|---|---|---|---|---|
| Brand | Hewlett Packard Enterprise | Hewlett Packard Enterprise | Hewlett Packard Enterprise | Hewlett Packard Enterprise | SK Hynix | Brute Networks | TWINRAM |
| Package | 288-pin RDIMM | 288-pin RDIMM - same | 288-pin RDIMM - same | 288-pin RDIMM - same | 288-pin RDIMM - same | 288-pin RDIMM - same | 288-pin RDIMM - same |
| Capacity | 32 GB | 32 GB | 32 GB | 32 GB | 32 GB | 32 GB | 32 GB |
| Speed Grade | DDR5-5600 (PC5-44800) | DDR5-5600 | DDR5-5600 | DDR5-5600 | DDR5-5600 | DDR5-5600 | DDR5-5600 (PC5-44800) |
| Rank Configuration | 2Rx8 (Dual Rank) | 2Rx8 | 2Rx8 | 1Rx4 (Single Rank) | 2Rx8 | 2Rx8 | 2Rx8 |
| CAS Latency | CL46 (46-45-45) | CL46 | CL46 | CL46 | CL46 | CL46 | CL46 |
| Operating Voltage | 1.10 V | 1.10 V | 1.10 V | 1.10 V | 1.10 V | 1.10 V | 1.10 V |
| ECC | Yes (Registered, EC8) | Yes (Registered) | Yes (Registered) | Yes (Registered) | Yes (Registered) | Yes (Registered) | Yes (Registered) |
| HPE SmartMemory Authentication | Yes (native HPE firmware) | Yes (native HPE firmware) | Yes (native HPE firmware) | Yes (native HPE firmware) | No (JEDEC-only) | No (aftermarket firmware) | No (aftermarket firmware) |
| HPE Warranty Entitlement | Lifetime (when in supported HPE server) | Lifetime (HPE) | Lifetime (HPE) | Lifetime (HPE) | Aftermarket vendor only | Aftermarket vendor only | Lifetime Limited (TWINRAM) |
Key Differentiators
- Native HPE SmartMemory firmware with iLO integration (vs P64706-B21-BN (Brute Networks aftermarket))
- Original HPE option-part-numbered SKUs for entitlement tracking (vs P64706-B21-BN (Brute Networks aftermarket))
- Dual-rank 2Rx8 architecture for maximum rank interleaving (vs P65254-001 (HPE 1Rx4 single-rank variant))
Design Notes
Do not mix DDR5-5600 modules of different rank counts (1Rx4 + 2Rx8) in the same channel without verifying supported configurations in the HPE QuickSpecs. Most HPE Gen11 servers require matched rank configurations across all populated channels; mixing may cause the system to downclock or refuse to boot. HPE iLO will log a 'Memory Configuration Error' if population rules are violated. Always populate channels symmetrically (e.g., 1 DIMM per CPU first, then add second DIMM per channel) for optimal bandwidth.
DDR5 RDIMMs run cooler than DDR4 RDIMMs at the same capacity (1.10V vs 1.20V = ~17% power reduction), but densely populated Gen11 servers (24+ DIMMs) still demand adequate chassis airflow. Ensure intake air temperature remains within HPE's 35C derating curve; each 5C above nominal reduces DIMM lifetime by ~10%. The on-module PMIC generates localized heat and should not be covered by insulating materials or adjacent heat-generating components.
DDR5 RDIMMs must be installed in matched pairs across memory controllers for full bandwidth. In dual-CPU HPE Gen11 platforms (DL380 Gen11), install DIMMs in CPU1 slots first, then CPU2 slots, maintaining identical slot population between the two processors. Mixing P64706-B21 with lower-speed DDR5 modules (e.g., DDR5-4800) will cause the entire channel to operate at the slower speed, negating the bandwidth advantage.
DDR5-5600 places stringent signal-integrity requirements on the DIMM slot, motherboard routing, and PMIC decoupling. The on-module PMIC handles local voltage regulation but introduces additional noise that must be decoupled with high-quality ceramic capacitors on the DIMM PCB. Always use HPE-qualified memory modules in supported servers - HPE validates signal integrity, timing closure, and PMIC behavior as part of platform qualification, which third-party modules may not replicate.
Compliance Information
RoHS and REACH compliance per HPE product environmental specifications. AEC-Q100 not applicable for server DRAM modules. Conflict minerals compliance per HPE supplier responsibility program. Halogen-free status not specified in available web data.
