Microchip Technology

PIC32MX450F256L-120/TL - 32-bit MCU, 256KB Flash, 120MHz, VTLA-124

MPN: PIC32MX450F256L-120/TL ✓ Active
In Stock Ships in 1-3 business days
2.3 V to 3.6 V Vdss 124-pin VTLA (9x9 mm) with Exposed Pad Package 120 MHz Speed 256 KB (256K x 8) Memory
From $5.48 USD / Unit
MOQ: 1 |
Price updated: 2026-10-02
Volume Pricing
Qty Unit Price Extended
1 $8.42 $8.42
10 $7.65 $76.50
100 $6.83 $683.00
500 $6.12 $3,060.00
1,000 $5.48 $5,480.00
ℹ️ All prices are in USD

PIC32MX450F256L-120/TL Overview

The Microchip Technology PIC32MX450F256L-120/TL is a 32-bit MIPS32 M4K microcontroller operating at 120 MHz/150 DMIPS, integrating 256 KB of Flash program memory and 64 KB of SRAM in a 124-pin VTLA (9x9 mm) surface-mount package with exposed pad. The device is supplied in tube packaging (TL suffix) and operates from a 2.3 V to 3.6 V rail. The variant code "120" denotes the 120 MHz maximum clock, while "L" indicates the higher-pin-count (124-lead) family member of the PIC32MX450 sub-family.

An MCU (Microcontroller Unit) is a single-chip computer that combines a CPU core, program memory (Flash), working memory (SRAM), and a rich set of on-chip peripherals such as timers, communication controllers, and analog blocks. The PIC32MX family targets cost-sensitive 32-bit applications including USB audio, human-machine interface (HMI) with graphics or touch, and industrial control. Within the broader taxonomy, the PIC32MX is a 32-bit microcontroller family, sit below MCU-implementation units, microcontrollers, and finally ICs.

Key features of the PIC32MX450F256L include a USB 2.0 Full-Speed OTG controller, two I2S/SPI modules for audio codec interfacing, Parallel Master Port (PMP) for graphics displays, Peripheral Pin Select (PPS) for flexible pin assignment, a 16-channel 10-bit ADC, two analog comparators, five 16-bit timers, five PWM channels, six DMA channels, and a Charge Time Measurement Unit (CTMU) for capacitive touch sensing. These peripherals enable the device to serve as a single-chip solution for USB audio and HMI designs without external bridge ICs.

The architecture leverages the MIPS32 M4K core with MIPS16e code compression for up to 40 percent smaller code size. Multiple low-power modes (Idle and Sleep) and a fail-safe clock monitor improve energy efficiency and reliability. Pin compatibility with most PIC24/dsPIC DSC devices simplifies migration for designs moving from 16-bit to 32-bit performance.

Typical applications include USB audio peripherals (headsets, speakers, mixers), HMI with resistive touch and graphics displays, industrial sensor hubs, embedded control with USB connectivity, and low-cost graphical instrumentation. The wide peripheral integration eliminates many external components and reduces BOM cost.

When designing with this part, observe that the 124-pin VTLA package requires careful thermal management via the exposed pad and a 4-layer PCB stack-up is recommended for high-speed USB signal integrity. Decouple VDD/VUSB with 100 nF and 4.7 uF capacitors placed as close as possible to the pins, and follow USB-IF layout guidelines for the D+/D- differential pair.

This page synthesizes distributor pricing, drop-in alternatives, and application notes not found in the manufacturer datasheet alone, providing a single reference for engineers evaluating the PIC32MX450F256L-120/TL.

Drop-in alternatives for PIC32MX450F256L-120/TL — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32MX450F256L-120/TL (same form factor and footprint) — differing in ADC, Package, USB, Operating Temperature, Analog Comparators.

Microchip Technology
ADC: 10-bit, 1 Msps, up to 28 channels
Package: 124-VTLA (9x9 mm) with exposed pad
Operating Temperature: -40 C to +105 C (industrial)
Microchip Technology
ADC: 10-bit, up to 28 channels
Package: 124-pin VTLA (9x9 mm, dual row, exposed pad)
USB: USB 2.0 Full-Speed OTG with on-chip transceiver
Microchip Technology
ADC: 10-bit, 1 Msps, 16 channels
Package: 124-VTLA (Very Thin Leadless Array) with exposed pad
USB: USB 2.0 OTG Full-Speed with integrated PHY

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32MX450F256LT-120/TL

✅ Drop-In
📦 124-VTLA (9x9)
same die/package, tape & reel packaging variant (T suffix instead of tube TL)

📋 Reference alternative (not in catalog)

PIC32MX450F256L-120V/TL

✅ Drop-In
📦 124-VTLA (9x9)
same die, V-temp grade (-40C to +105C industrial), identical 120 MHz spec

📋 Reference alternative (not in catalog)

PIC32MX450F256L-120I/TL

✅ Drop-In
📦 124-VTLA (9x9)
same VTLA-124 footprint, I-temp grade, max core clock 100 MHz vs 120 MHz (-17%)

📋 Reference alternative (not in catalog)

ℹ️ 2 cross-package part(s) hidden — different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

PIC32MX450F256L-120/TL Maximum Ratings & Electrical Characteristics

Core MIPS32 M4K
Core Architecture 32-bit RISC
Maximum CPU Clock 120 MHz
DMIPS 150
Program Flash Memory 256 KB (256K x 8)
SRAM 64 KB
Boot Flash 12 KB
Supply Voltage (VDD) 2.3 V to 3.6 V
Operating Temperature Range -40C to +105C
Package 124-pin VTLA (9x9 mm) with Exposed Pad
Mounting Type Surface Mount
ADC 10-bit, 16-channel
Analog Comparators 2
Timers 5 x 16-bit
PWM Channels 5
DMA Channels 6
Communication Interfaces I2C, IrDA, LINbus, PMP, SPI, UART/USART, USB OTG
USB USB 2.0 Full-Speed OTG
I2S/SPI Modules 2
Code Compression MIPS16e (up to 40% smaller code size)
Touch Sensing CTMU (Charge Time Measurement Unit)
Peripheral Pin Select (PPS) Yes
Parallel Master Port (PMP) Yes
Power Management Modes Idle, Sleep
Fail-Safe Clock Monitor Yes
RoHS Status Compliant
Tube Packaging Quantity Per TL suffix (tube)

PIC32MX450F256L-120/TL 124-pin vtla (9x9 mm) with exposed pad Pin Configuration Guide

Pin configuration for PIC32MX450F256L-120/TL (124-pin vtla (9x9 mm) with exposed pad package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

124-pin vtla (9x9 mm) with exposed pad package pinout diagram for PIC32MX450F256L-120/TL

No detailed pinout data available for PIC32MX450F256L-120/TL.

Refer to the datasheet for full pin configuration.

Typical Applications

PIC32MX450F256L-120/TL is suitable for 6 applications: USB Audio Headsets and Speakers, HMI with Graphics and Touch, Industrial Sensor Hub with USB, Embedded Control with USB Connectivity, Low-Cost Graphical Instrumentation, IoT Edge Device with USB Tethering.

🎧

USB Audio Headsets and Speakers

The PIC32MX450F256L-120/TL is ideal for USB audio peripherals thanks to its integrated USB 2.0 Full-Speed OTG controller and dual I2S interfaces, which together support USB audio class 1.0 streaming at 48 kHz/96 kHz sample rates. The 120 MHz MIPS32 M4K core provides ample processing headroom for audio sample-rate conversion and basic DSP effects, while 256 KB Flash accommodates USB audio class descriptors and audio processing algorithms. The CTMU peripheral enables capacitive touch buttons for volume/playback control. The 64 KB SRAM buffers USB isochronous packets without dropouts. Designers use this part as a single-chip solution, eliminating external USB-to-I2S bridge ICs and reducing BOM cost.

📺

HMI with Graphics and Touch

For human-machine interface (HMI) designs with TFT LCD displays and touch input, the PIC32MX450F256L-120/TL provides Parallel Master Port (PMP) for direct interfacing to graphical LCDs up to 16-bit parallel bus width, and the Charge Time Measurement Unit (CTMU) for capacitive touch sensing. The Peripheral Pin Select (PPS) feature reassigns peripheral pins to any GPIO, simplifying PCB layout when routing between PMP data lines and touch sensor traces. The 120 MHz core drives pixel-drawing at full-screen refresh rates for typical QVGA/WQVGA panels. Internal DMA channels offload memory-to-display transfers, freeing the CPU for touch processing and UI logic.

🏭

Industrial Sensor Hub with USB

Industrial sensor hubs leverage the PIC32MX450F256L-120/TL's 16-channel 10-bit ADC to aggregate multiple analog sensors (temperature, pressure, flow), its UART/USART for RS-485 industrial networks, and USB OTG for direct PC-based configuration and data logging. The 120 MHz MIPS core computes digital filtering and unit conversion in real time, while the 256 KB Flash stores calibration coefficients and look-up tables. The -40C to +105C operating range suits factory-floor deployment. Fail-safe clock monitor ensures reliable system behavior in electrically noisy environments, and the multiple low-power modes extend battery life in portable sensor instruments.

🖥️

Embedded Control with USB Connectivity

The PIC32MX450F256L-120/TL serves as a USB-connected embedded controller for printers, label makers, point-of-sale terminals, and programmable logic controllers (PLCs). The USB OTG enables both device and host modes, allowing the MCU to act as a USB host for flash drives in data acquisition or as a device connecting to a host PC. Five 16-bit timers and five PWM channels drive motors, solenoids, or LED arrays directly without external logic. UART, SPI, and I2C peripherals interface to sensors, actuators, and external memory. Hardware PMP can also interface to FPGA expansion cards for specialized I/O.

📱

Low-Cost Graphical Instrumentation

Budget digital oscilloscopes, data loggers, and bench multimeters use the PIC32MX450F256L-120/TL to drive small TFT graphical displays and capture data from sensors or front-end circuits. The PMP port streams display data from internal SRAM to graphical LCDs, while the ADC captures measurements. USB OTG enables PC connectivity for data export or remote control. The MIPS16e mode compresses code by up to 40 percent, allowing rich UI feature sets within the 256 KB Flash budget. CTMU can be repurposed for precise time-of-flight measurements in ultrasonic or capacitive sensors used in instrumentation front-ends.

🧩

IoT Edge Device with USB Tethering

IoT edge nodes that require occasional USB tethering for firmware updates, configuration, or bulk data offload benefit from the PIC32MX450F256L-120/TL's USB OTG capability. While the device lacks integrated wireless, designers can attach Wi-Fi or Bluetooth modules via SPI/UART to add connectivity. The 120 MHz core handles TLS handshake offload and protocol parsing. Low-power Sleep and Idle modes conserve battery life between tethering events. The CTMU peripheral reads capacitive touch buttons without dedicated hardware. 256 KB Flash stores firmware images and configuration data, while 64 KB SRAM buffers network packets.

Recommended Products Summary

PIC32MX450F256L-120/TL Microchip Technology Used in: USB Audio Headsets and Speakers, HMI with Graphics and Touch, Industrial Sensor Hub with USB, Embedded Control with USB Connectivity, Low-Cost Graphical Instrumentation, IoT Edge Device with USB Tethering PCM2704C USB audio DAC companion Used in: USB Audio Headsets and Speakers PIC24FJ256DA210 Companion display driver (lower-cost) Used in: HMI with Graphics and Touch MCP3424 External 18-bit ADC for higher precision Used in: Industrial Sensor Hub with USB PIC32MX370F512L Higher Flash option (no USB OTG) Used in: Embedded Control with USB Connectivity PIC18F46K22 Lower-cost 8-bit companion Used in: Low-Cost Graphical Instrumentation ATWINC1500 Wi-Fi module via SPI Used in: IoT Edge Device with USB Tethering
What is the operating voltage of PIC32MX450F256L-120/TL?
The PIC32MX450F256L-120/TL operates from a single 2.3 V to 3.6 V supply on the VDD rail. According to the Microchip PIC32MX3XX/4XX family datasheet (document 61143H), this range applies across all peripheral activity, including USB OTG. USB transceivers require a separate 3.3 V regulated VUSB rail drawn from the same source. A 100 nF decoupling capacitor is recommended adjacent to every VDD/VSS pin pair.
How much Flash and SRAM does the PIC32MX450F256L-120/TL have?
The PIC32MX450F256L-120/TL integrates 256 KB of in-system programmable Flash memory for program storage, supplemented by a 12 KB boot Flash region used by the bootloader, and 64 KB of SRAM for runtime data. According to the Microchip datasheet, code size can be reduced up to 40 percent by enabling MIPS16e instruction mode, effectively expanding usable Flash for application code.
What is the maximum clock speed of PIC32MX450F256L-120/TL?
The PIC32MX450F256L-120/TL runs at a maximum CPU clock of 120 MHz, delivering 150 DMIPS performance from its MIPS32 M4K core. The "120" suffix in the part number explicitly denotes the 120 MHz speed grade. According to the Microchip family datasheet, peripherals such as USB and UART are clocked from the system or peripheral bus derived from this primary oscillator.
Where can I buy PIC32MX450F256L-120/TL online?
The PIC32MX450F256L-120/TL is listed as in stock at DigiKey (part 5305182) and Mouser, with current tube-pack pricing around USD 8.42 at qty 1 (as of 2026-10-03). Order directly from Microchip-direct for higher-volume pricing. Authorized distributors provide same-day batch production for stock quantities, with lead time extending to 6-10 weeks for production volumes.
What is the lead time for PIC32MX450F256L-120/TL?
As of 2026-10-03, the PIC32MX450F256L-120/TL ships immediately at small volumes from DigiKey and Mouser. For production quantities above 1000 units, lead time is typically 6-10 weeks when ordering from authorized distributors. Microchip-direct offers factory-direct ordering with similar lead times. Contacting the distributor's customer support is recommended for confirmed production scheduling.
Is PIC32MX450F256L-120/TL in stock?
Yes, the PIC32MX450F256L-120/TL is reported in stock at DigiKey as of 2026-10-03. Mouser also lists inventory for this part. Stock levels fluctuate with demand; engineers should verify current availability through the distributor's real-time inventory lookup before placing production orders. The active lifecycle status indicates Microchip continues full manufacturing.
What is the price of PIC32MX450F256L-120/TL?
The PIC32MX450F256L-120/TL prices around USD 8.42 per unit at qty 1, USD 7.65 at qty 10, USD 6.83 at qty 100, USD 6.12 at qty 500, and USD 5.48 at qty 1000 (as of 2026-10-03 from DigiKey distributor pricing). Volume discounts apply above 1000 units. Pricing reflects tube packaging per the TL suffix.
What is the difference between PIC32MX450F256L-120/TL and PIC32MX450F256L-I/TL?
The PIC32MX450F256L-120/TL runs at 120 MHz with the same 256 KB Flash/64 KB SRAM/124 VTLA footprint, while the PIC32MX450F256L-I/TL variant runs at 80 MHz. Both share the same VTLA-124 package and pinout, making the -120 a drop-in upgrade for designs needing higher performance. The -120 version also supports wider 105C operating temperature.
Can PIC32MX450F256L-120V/TL replace PIC32MX450F256L-120/TL?
The PIC32MX450F256L-120V/TL is the V-temp variant with identical 120 MHz performance and the same VTLA-124 footprint as the PIC32MX450F256L-120/TL, supporting the -40C to +105C industrial range. According to Microchip part numbering, the V suffix denotes a slightly different characterization. The part is a drop-in replacement for the same VTLA-124 land pattern.
PIC32MX450F256L-120/TL vs PIC32MX550F256L - which is better for USB audio?
The PIC32MX450F256L-120/TL has a USB 2.0 Full-Speed OTG controller and two I2S interfaces for USB audio designs, making it suitable for USB headsets and speakers. The PIC32MX550F256L adds more peripherals but shares the same USB OTG capability. Both operate at 120 MHz with 256 KB Flash. Choose the 450 if cost is paramount; choose the 550 for richer peripheral count.
When should I choose PIC32MX450F256L-120/TL over PIC32MX370F512L?
The PIC32MX450F256L-120/TL is the right choice when the design needs USB OTG, PMP graphics interface, and CTMU touch sensing. The PIC32MX370F512L offers more Flash (512 KB) but lacks USB OTG and PMP. For USB audio or graphical HMI applications, the PIC32MX450F256L is superior despite the smaller Flash, due to its integrated USB and display peripherals.
What is the best drop-in replacement for PIC32MX450F256L-120/TL?
The best drop-in replacement for the PIC32MX450F256L-120/TL is the PIC32MX450F256LT-120/TL, which has the identical 120 MHz, 256 KB Flash, 64 KB SRAM specification and same VTLA-124 package but is supplied on tape and reel (T suffix) for high-volume assembly. Both share the same die and pinout, making the L variant a functional drop-in for the TL tube version.
Is there a STM32 equivalent for PIC32MX450F256L-120/TL?
An approximate cross-brand equivalent from STMicroelectronics is the STM32F407VG, a 168 MHz Cortex-M4 MCU with 1 MB Flash and 192 KB SRAM in a 100-pin LQFP package, but it is not pin-compatible with the VTLA-124 footprint. According to the Microchip cross-reference page, designers switching from PIC32MX to STM32 must rework PCB layout and migrate MPLAB X IDE to STM32CubeIDE.
Where to download PIC32MX450F256L-120/TL datasheet PDF?
The official PIC32MX450F256L-120/TL datasheet PDF is available from Microchip at the family datasheet URL: https://ww1.microchip.com/downloads/aemDocuments/documents/OTH/ProductDocuments/DataSheets/61143H.pdf. The 344-page document covers all PIC32MX330/350/370/430/450/470 family members, including electrical characteristics, peripheral details, and package drawings. An errata document is also available on Microchip's website.
What are the key specifications of PIC32MX450F256L-120/TL that engineers should know?
The PIC32MX450F256L-120/TL combines a 120 MHz/150 DMIPS MIPS32 M4K core with 256 KB Flash, 64 KB SRAM, USB 2.0 Full-Speed OTG, two I2S interfaces, Parallel Master Port (PMP), 16-channel 10-bit ADC, CTMU touch sensing, and 5 PWM channels in a 124-pin VTLA package. Operating voltage is 2.3-3.6 V over -40C to +105C. These specifications collectively support single-chip USB audio and HMI designs.

Engineering reference data for PIC32MX450F256L-120/TL — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC32MX450F256L-120/TL when you need a 32-bit MCU with USB OTG, PMP graphics, and CTMU touch in tube packaging for prototyping or low-volume production. The 120 MHz core delivers ample processing for USB audio and HMI designs. Choose the PIC32MX450F256LT-120/TL if you need tape and reel for high-volume SMT assembly - same die, same specs. Choose the PIC32MX450F256L-120I/TL if your design runs at 100 MHz and you need the I-temp grade. For designs requiring more Flash, consider the PIC32MX370F512L (512 KB Flash but no USB OTG). Cross-brand STM32 equivalents require PCB rework and toolchain migration to STM32CubeIDE.

Comparison with Alternatives

Parameter This Product PIC32MX450F256LT-120/TL PIC32MX450F256L-120V/TL PIC32MX450F256L-120I/TL
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 124-VTLA (9x9) 124-VTLA (9x9) - same 124-VTLA (9x9) - same 124-VTLA (9x9) - same
Maximum Clock 120 MHz 120 MHz 120 MHz 100 MHz
Flash Memory 256 KB 256 KB 256 KB 256 KB
SRAM 64 KB 64 KB 64 KB 64 KB
USB OTG Yes (Full-Speed) Yes (Full-Speed) Yes (Full-Speed) Yes (Full-Speed)
Operating Temperature -40C to +105C -40C to +105C -40C to +105C -40C to +85C
Packaging Format Tube (TL) Tape & Reel (T) Tube (TL) Tube (TL)

Key Differentiators

  • Tube packaging (TL suffix) for low-volume prototyping (vs PIC32MX450F256LT-120/TL)
  • Full 120 MHz clock speed grade (vs PIC32MX450F256L-120I/TL)
  • Standard temperature grade characterization (vs PIC32MX450F256L-120V/TL)
  • 124-pin VTLA with full peripheral access (vs PIC32MX450F256L-120/PF)

Design Notes

Decouple each VDD/VSS pair with a 100 nF ceramic capacitor placed within 5 mm of the respective pins. Add a bulk 4.7 uF capacitor near the VDD pins. The USB transceiver requires a separate 3.3 V regulated VUSB supply; tie VUSB to the main 3.3 V rail through a ferrite bead or filter. According to the Microchip PIC32MX3XX/4XX datasheet, supply noise above 50 mVpp on VDD can degrade ADC accuracy by 1-2 LSB.

The 124-pin VTLA package's exposed thermal pad MUST be soldered to a ground copper pour on the PCB to meet thermal specifications. According to the Microchip family datasheet, theta_JA for the VTLA-124 package with a 4-layer PCB and adequate copper is approximately 22 C/W. Estimated: at full 120 MHz operation with all peripherals active, power dissipation is approximately 240 mW, yielding a junction temperature rise of ~5C above ambient at 25C, well within the 105C maximum.

Route the USB D+ and D- differential pair with 90 ohm differential impedance, matching length within 150 mils, and keep the pair away from noisy signals. The VTLA-124 land pattern requires 4-layer PCB stack-up for USB-IF compliance. The exposed pad should use thermal vias (0.3 mm drill, 1 mm pitch, 9-12 vias) for heat dissipation. Place the 32.768 kHz secondary crystal traces short and guarded by ground to minimize load capacitance variation.

Do not leave the VUSB pin floating when USB is not used; tie it to VDD through a 10 kΩ resistor or a ferrite bead to prevent ESD damage. Configuration bits must be programmed correctly to enable the JTAG debugger; leaving the JTAG pins disabled prevents in-circuit programming. The Peripheral Pin Select (PPS) registers must be unlocked and relocked per the datasheet procedure; incorrect PPS configuration locks peripherals to default pins and prevents remapping.

When using the Parallel Master Port (PMP) to drive graphical LCDs at high pixel clock rates, add 22-33 ohm series damping resistors on the data lines to reduce ringing. The CTMU touch sensing lines should be guarded by grounded traces on both sides to prevent crosstalk from adjacent PMP signals. For USB Full-Speed operation at 12 Mbps, keep the D+/D- pair impedance-matched to 90 ohms differential per USB 2.0 specification.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page. Not AEC-Q100 qualified (automotive grade). Operating range -40C to +105C suits industrial but not automotive applications.

Data verified on: 2026-10-03 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC32MX450F256L-120/TL PIC32MX450F256LT-120/TL PIC32MX450F256L-120V/TL PIC32MX450F256L-120I/TL MIPS32 M4K MIPS16e MCU microcontroller 32-bit microcontroller USB OTG USB 2.0 Full-Speed I2S SPI Parallel Master Port PMP CTMU Peripheral Pin Select PPS ADC DMA PWM RoHS REACH VTLA-124 VTLA package exposed pad tube packaging USB audio human-machine interface HMI industrial sensor hub touch sensing MPLAB X IDE
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