Microchip Technology

PIC18F4450-I/P - 8-bit 48MHz 16KB Flash USB MCU | Microchip

MPN: PIC18F4450-I/P ✓ Active
In Stock Ships in 1-3 business days
4.2 V to 5.5 V Vdss 40-pin PDIP (DIP-40, 0.600 inch) Package 48 MHz Speed 16 KB (8K x 16) Flash Memory
From $6.05 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $9.45 $9.45
10 $8.62 $86.20
100 $7.55 $755.00
500 $6.78 $3,390.00
1,000 $6.05 $6,050.00
ℹ️ All prices are in USD

PIC18F4450-I/P Overview

The Microchip Technology PIC18F4450-I/P is an 8-bit RISC microcontroller from the PIC18F family that integrates a Full-Speed USB 2.0 (12 Mbit/s) transceiver and 16 KB of enhanced Flash program memory in a 40-pin PDIP through-hole package. Operating at up to 48 MHz system clock from a 4.2 V to 5.5 V supply, the device delivers approximately 16 MIPS throughput and combines a 10-bit ADC with up to 13 channels, a USART, MSSP (SPI/I2C), nanoWatt power management, and a 35-pin I/O complement.

What is a PIC18F microcontroller? PIC18F is Microchip's enhanced 8-bit PIC microcontroller family, positioned between the baseline PIC16 and the 16-bit dsPIC families in Microchip's portfolio. These parts share a RISC Harvard architecture, a unified instruction set, and a powerful peripheral set, making them ideal for embedded control applications that require deterministic interrupt response, low power, and easy migration between pin counts. The 4450 sub-family specifically adds an on-chip USB 2.0 Full-Speed transceiver and is targeted at applications such as human-interface devices, USB-to-UART bridges, and embedded hosts that previously required an external USB controller.

Key features include 16 KB (8K x 16) Flash program memory, 768 bytes of RAM, 256 bytes of EEPROM, 34 digital I/O pins, 13 10-bit ADC channels, two 8-bit timers and three 16-bit timers, a Capture/Compare/PWM module, hardware USB 2.0 Full-Speed with internal pull-up resistor, and nanoWatt power-saving modes with idle and sleep states drawing only microamps. The 40-pin PDIP (0.600 inch) package allows hand-soldering, breadboarding, and socketed prototypes.

The architecture uses an 8-bit data path with a 16-bit instruction word and a hardware multiplier for single-cycle 8x8 multiplication. The integrated USB SIE handles bus enumeration, bulk/interrupt/isochronous endpoints, and suspend/resume signaling, eliminating external transceivers. On-chip peripherals are prioritized via a vectored interrupt controller with two priority levels, allowing deterministic real-time response for USB traffic and motor-control PWM.

Typical applications include USB human-interface devices (HID mice, keyboards, custom peripherals), USB-to-serial converter dongles, low-cost data loggers, sensor read-out boards, industrial control panels, and educational/training boards where the through-hole package simplifies lab work.

When designing with the PIC18F4450, supply decoupling of at least 100 nF near each power pin and a 10 uF bulk capacitor on VDD is essential, and the USB D+/D- traces must be 90 ohm differential and length-matched. The internal 48 MHz PLL is enabled by configuration fuses and requires the HS or HSPLL oscillator mode for USB operation; an external 4, 8, 12, 16, 20, 24, or 48 MHz crystal with appropriate load capacitors must be selected per the oscillator configuration fuse settings.

This page synthesizes distributor pricing, drop-in same-package alternatives, comparison parameters, and practical design notes not collated on a single distributor product page.

Drop-in alternatives for PIC18F4450-I/P — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F4450-I/P (same form factor and footprint) — differing in Package, Timers, ADC, Operating Temperature, Core Architecture.

Microchip Technology
Package: 28-pin SOIC (SO)
Timers: 2x 8-bit + 1x 16-bit
ADC: 10-bit, up to 9 channels
Microchip Technology
Package: 40-pin PDIP (0.600", 15.24 mm)
Timers: 1 x 8-bit, 3 x 16-bit
ADC: 10-channel, 12-bit
Microchip Technology
Package: TQFP-44 (PT), 10x10 mm, 0.8 mm pitch
Timers: 4 (8-bit / 16-bit mix)
ADC: 10-bit, 13 channels
Microchip Technology
Package: 40-pin PDIP (0.600"/15.24 mm)
Timers: 4 (Timer0/1/2/3)
Operating Temperature: -40C to +125C (Extended, -E grade)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F4550-I/P

✅ Drop-In
📦 40-pin PDIP
Flash 32 KB vs 16 KB (+100%), same peripherals and USB 2.0 FS, same 40-pin PDIP footprint

📋 Reference alternative (not in catalog)

PIC18F4458-I/P

✅ Drop-In
Microchip Technology
📦 40-pin PDIP
PIC18F 8-bit Harvard RISC · 16-bit · 8-bit · 48 MHz · 24 KB (12K x 16 words) · 2 KB · 256 bytes

✓ In Stock

$4.62 / Unit

View Datasheet →

PIC18F4455-I/P

✅ Drop-In
📦 40-pin PDIP
Flash 24 KB vs 16 KB (+50%), same USB and peripherals, same 40-pin PDIP footprint

📋 Reference alternative (not in catalog)

PIC18LF4450-I/P

✅ Drop-In
📦 40-pin PDIP
same die, 2.0-5.5 V wide VDD vs 4.2-5.5 V (lower-voltage operation), same USB and 40-pin PDIP footprint

📋 Reference alternative (not in catalog)

PIC18F45K50-I/P

✅ Drop-In
📦 40-pin PDIP
Flash 32 KB vs 16 KB (+100%), XLP nanoWatt, same 40-pin PDIP and USB 2.0 FS footprint

📋 Reference alternative (not in catalog)

PIC18F4450-I/P Maximum Ratings & Electrical Characteristics

Core PIC18F (8-bit RISC)
Program Memory 16 KB (8K x 16) Flash
RAM 768 bytes
EEPROM 256 bytes
Max CPU Clock 48 MHz
Instruction Throughput 16 MIPS
Supply Voltage (VDD) 4.2 V to 5.5 V
I/O Pins 34 (port A/B/C/D/E subset)
ADC 10-bit, up to 13 channels
USB USB 2.0 Full-Speed (12 Mbit/s), internal transceiver
Timers 2 x 8-bit, 3 x 16-bit
CCP/ECCP Modules 2 (Capture/Compare/PWM)
Serial Interfaces EUSART, MSSP (SPI / I2C)
Operating Temperature -40C to +85C (Industrial)
Package 40-pin PDIP (DIP-40, 0.600 inch)
Mounting Type Through-Hole
MSL Level 1 (Not Moisture Sensitive)
RoHS Status Compliant
Lead-Free Yes (matte tin)
Power-Saving Modes nanoWatt (Idle, Sleep, etc.)

PIC18F4450-I/P Pin Configuration

DIP-40 Package Pinout Diagram DIP-40 40-pin dual inline, 7.62mm pitch, JEDEC MS-001. 1 40 2 39 3 38 4 37 5 36 6 35 7 34 8 33 9 32 10 31 11 30 12 29 13 28 14 27 15 26 16 25 17 24 18 23 19 22 20 21 DIP-40
Pin 1 VPP/RE3 — Programming voltage / RE3 general-purpose I/O
Pin 2 RA0/AN0 — PORTA bit 0 / analog input 0
Pin 3 RA1/AN1 — PORTA bit 1 / analog input 1
Pin 4 RA2/AN2/VREF- — PORTA bit 2 / analog input 2 / ADC negative reference
Pin 5 RA3/AN3/VREF+ — PORTA bit 3 / analog input 3 / ADC positive reference
Pin 6 RA4/T0CKI/C1OUT — PORTA bit 4 / TMR0 clock / comparator 1 output
Pin 7 RA5/AN4/SS/C2OUT — PORTA bit 5 / analog input 4 / SPI slave select / comparator 2 output
Pin 8 VSS — Ground reference
Pin 9 OSC1/CLKI — Crystal input / external clock input
Pin 10 OSC2/CLKO — Crystal output / clock output
Pin 11 RC0/T1OSO/T1CKI — PORTC bit 0 / TMR1 oscillator output / TMR1 clock
Pin 12 RC1/T1OSI/CCP2 — PORTC bit 1 / TMR1 oscillator input / CCP2
Pin 13 RC2/CCP1 — PORTC bit 2 / CCP1
Pin 14 VUSB — Internal USB 3.3V regulator output (connect 220 nF to VSS)
Pin 15 RC4/D-/VMO — PORTC bit 4 / USB D- / ICD voltage monitor output
Pin 16 RC5/D+/VPO — PORTC bit 5 / USB D+ / ICD voltage monitor output
Pin 17 RC6/TX/CK — PORTC bit 6 / EUSART TX / EUSART clock
Pin 18 RC7/RX/DT — PORTC bit 7 / EUSART RX / EUSART data
Pin 19 VSS — Ground reference
Pin 20 VDD — Positive supply 4.2-5.5 V
Pin 21 RB0/AN12/INT0 — PORTB bit 0 / analog input 12 / external interrupt 0
Pin 22 RB1/AN10/INT1 — PORTB bit 1 / analog input 10 / external interrupt 1
Pin 23 RB2/AN8/INT2 — PORTB bit 2 / analog input 8 / external interrupt 2
Pin 24 RB3/AN9/CCP2 — PORTB bit 3 / analog input 9 / CCP2 alternate
Pin 25 RB4/AN11/KBI0 — PORTB bit 4 / analog input 11 / KBI interrupt
Pin 26 RB5/KBI1/PGM — PORTB bit 5 / KBI interrupt / LVP programming
Pin 27 RB6/KBI2/PGC — PORTB bit 6 / KBI / ICSP clock
Pin 28 RB7/KBI3/PGD — PORTB bit 7 / KBI / ICSP data
Pin 29 VSS — Ground reference
Pin 30 VDD — Positive supply 4.2-5.5 V
Pin 31 VSS — Ground reference
Pin 32 RD0 — PORTD bit 0
Pin 33 RD1 — PORTD bit 1
Pin 34 RD2 — PORTD bit 2
Pin 35 RD3 — PORTD bit 3
Pin 36 RC3 — PORTC bit 3
Pin 37 RD4 — PORTD bit 4
Pin 38 RD5 — PORTD bit 5
Pin 39 RD6 — PORTD bit 6
Pin 40 RD7 — PORTD bit 7

Typical Applications

PIC18F4450-I/P is suitable for 7 applications: USB HID Keyboard and Mouse, USB-to-UART Serial Bridge, Embedded Sensor Data Logger, Industrial Control Panel Interface, Educational Microcontroller Trainer Board, Custom USB Bulk Transfer Device, USB-Connected Sensor Read-Out Board.

🧩

USB HID Keyboard and Mouse

The PIC18F4450-I/P is well suited to USB Human Interface Devices such as keyboards, mice, game controllers, and custom HID peripherals because it integrates a USB 2.0 Full-Speed transceiver with internal pull-up, eliminating the external interface IC. With 34 I/O pins it can scan a 6x6 matrix keyboard or read multiple buttons and encoders, while the 16 KB Flash is ample for HID descriptor tables, key debounce logic, and USB class firmware. The 48 MHz system clock supports the required 12 Mbit/s signaling, and 768 bytes RAM buffers HID reports without CPU stall. Used with the free Microchip MCHPFSUSB framework, a working USB HID device can be brought up in a day of development.

🔧

USB-to-UART Serial Bridge

In a USB-to-UART bridge dongle the PIC18F4450-I/P runs the CDC class driver from its internal USB transceiver, presenting a virtual COM port to the host while reading and writing bytes through its hardware EUSART at up to 115200 baud or higher. The on-chip USB SIE handles enumeration and suspend/resume, freeing the CPU to buffer characters and manage line-control signaling (RTS/CTS) through GPIO. Its 4.2-5.5 V supply range matches USB VBUS directly, and the 40-pin PDIP package suits through-hole prototype dongles. Compared to an FTDI cable, this approach is lower cost for high-volume OEM adapters, and the free Microchip CDC framework eliminates licensing fees.

📊

Embedded Sensor Data Logger

For a low-cost standalone data logger the PIC18F4450-I/P reads up to 13 analog sensors through its 10-bit ADC, time-stamps samples via a 16-bit timer, and stores results in the 256-byte EEPROM or streams to a host over USB. The 48 MHz CPU converts ADC channels at tens of kilohertz while leaving bandwidth for USB bulk transfers, and the nanoWatt sleep modes reduce quiescent current to under 2 uA for battery-powered deployments. The 40-pin PDIP footprint is breadboard-friendly for prototype hardware, and its 5 V tolerance on most I/O simplifies interfacing to legacy 5 V analog sensors that 3.3 V microcontrollers cannot read directly.

🏭

Industrial Control Panel Interface

The PIC18F4450-I/P can drive a small industrial HMI panel by scanning an 8x4 matrix keypad through its 34 I/O lines, refreshing a character LCD through the MSSP SPI, and reporting operator events back to a PLC over USB. Its 4.2-5.5 V operation tolerates noisy 24 V-derived industrial rails when paired with proper TVS and bulk filtering, and the 85C industrial temperature grade supports factory-floor enclosures. The 16 KB Flash fits menu and ModBus state machine code comfortably, while the 768-byte RAM handles display buffers. Compared to a separate keyboard controller IC, integrating the MCU eliminates extra components and BOM cost.

🎓

Educational Microcontroller Trainer Board

The PIC18F4450-I/P is an excellent MCU for university and training labs because the 40-pin PDIP package is breadboard-compatible, eliminating the soldering needed for SMD variants and allowing students to swap parts on a programmer socket. The on-chip USB simplifies programming and serial I/O demonstrations without external interface ICs, and the 16 KB Flash plus 768 bytes RAM is sufficient for class projects on interrupt-driven design, ADC sampling, and PWM motor control. The free MPLAB X IDE and XC8 C compiler remove licensing barriers, and the large Microchip PIC18F community provides example projects, application notes, and textbook tutorials.

💻

Custom USB Bulk Transfer Device

Engineers building proprietary USB bulk endpoints for test fixtures, firmware uploaders, or high-throughput sensor streaming benefit from the PIC18F4450-I/P's on-chip USB 2.0 Full-Speed (12 Mbit/s) transceiver and 16 KB Flash for class driver code. The 48 MHz CPU sustains bulk endpoint traffic with low interrupt latency, and the 768-byte RAM doubles as a USB endpoint buffer. The 40-pin PDIP package simplifies through-hole field replacement in test rigs, while the 5 V VBUS-direct supply avoids the need for a 3.3 V regulator. Used with the Microchip USB stack, custom bulk pipelines reach roughly 1 MB/s end-to-end, sufficient for many bench-instrument data links.

🔬

USB-Connected Sensor Read-Out Board

A USB-tethered sensor read-out board using the PIC18F4450-I/P streams 10-bit ADC conversions to a host at up to several kilosamples per second while the host configures acquisition parameters over USB control transfers. The 13 ADC channels cover thermocouples, photodiodes, and bridge sensors, while 16 KB Flash fits calibration tables and digital filtering. The 34 I/O pins provide digital control outputs to the analog front-end, and the 5 V operation matches many precision analog ICs without level shifters. Compared to off-the-shelf DAQ cards, this approach delivers a low-cost USB-native channel for lab automation.

Recommended Products Summary

PIC18F4550-I/P Drop-in upgrade with 32 KB Flash Used in: USB HID Keyboard and Mouse, USB-to-UART Serial Bridge, Embedded Sensor Data Logger, Industrial Control Panel Interface, Educational Microcontroller Trainer Board, Custom USB Bulk Transfer Device, USB-Connected Sensor Read-Out Board PIC18F4553-I/P USB + 12-bit ADC variant in 40-pin PDIP Used in: USB HID Keyboard and Mouse PIC18F4458-I/P Microchip Technology Used in: USB HID Keyboard and Mouse, Embedded Sensor Data Logger, Industrial Control Panel Interface, Educational Microcontroller Trainer Board, USB-Connected Sensor Read-Out Board PIC18LF4450-I/P Lower-voltage CDC bridge variant Used in: USB-to-UART Serial Bridge PIC18F45K50-I/P XLP variant in same 40-pin PDIP footprint Used in: Custom USB Bulk Transfer Device
What is the program memory size of PIC18F4450-I/P?
The PIC18F4450-I/P contains 16 KB (8K x 16 words) of enhanced Flash program memory, supplemented by 768 bytes of SRAM data memory and 256 bytes of EEPROM for non-volatile parameter storage. According to the Microchip PIC18F2450/4450 datasheet, the Flash supports ICSP (In-Circuit Serial Programming) and self-programming from the application, enabling field firmware upgrades through the USB port.
Does PIC18F4450-I/P include a USB transceiver on-chip?
Yes, the PIC18F4450 integrates a USB 2.0 Full-Speed (12 Mbit/s) Serial Interface Engine (SIE) and transceiver, supporting control, interrupt, bulk, and isochronous endpoints with internal 1.5 kohm pull-up on D+. This eliminates the need for an external USB interface IC and saves roughly 1 to 2 square centimeters of PCB area in HID, CDC, and USB-to-UART designs.
What is the maximum operating frequency of PIC18F4450-I/P?
The PIC18F4450-I/P runs from DC up to 48 MHz system clock, which corresponds to 16 MIPS instruction throughput. The HS or HSPLL oscillator mode with an external 4, 8, 12, 16, 20, 24, or 48 MHz crystal is required for USB operation; for non-USB applications the INTRC internal 8 MHz oscillator is sufficient and reduces BOM cost.
Where can I buy PIC18F4450-I/P online and what is the lead time?
The PIC18F4450-I/P is in active stock at major distributors including DigiKey, Mouser, and Microchip Direct as of 2026-09-27, with single-piece pricing near USD 9.45 and quantity-1000 pricing near USD 6.05. Lead time for factory-direct orders is typically 4 to 6 weeks for tube quantities, while authorized distributors commonly ship from stock within 1 to 3 business days.
What is the price of PIC18F4450-I/P?
As of 2026-09-27, distributor pricing for the PIC18F4450-I/P is approximately USD 9.45 at qty 1, USD 8.62 at qty 10, USD 7.55 at qty 100, USD 6.78 at qty 500, and USD 6.05 at qty 1000 on tube packaging. Volume pricing for OEM reels of 1000+ units typically drops below USD 5.50 per part when sourced through Microchip Direct or franchised distributors.
Is PIC18F4450-I/P in stock right now?
Yes, the PIC18F4450-I/P shows active stock across at least 12 distributor listings on Octopart and DigiKey as of 2026-09-27, with several thousand units available in tube packaging. Lifecycle status from Microchip remains ACTIVE, and the part is fully supported in MPLAB X IDE and the XC8 toolchain.
What is the difference between PIC18F4450-I/P and PIC18F4550-I/P?
Both parts share the same 40-pin PDIP footprint, 48 MHz CPU clock, on-chip USB 2.0 Full-Speed transceiver, and ADC; the key difference is program memory - the PIC18F4450 has 16 KB Flash while the PIC18F4550 has 32 KB Flash. They are pin-compatible drop-in alternatives, so you can upgrade to the 4550 if firmware exceeds 16 KB without any PCB change.
Can PIC18F4455-I/P replace PIC18F4450-I/P?
No, the PIC18F4455 is in a different package family (44-pin TQFP/PLCC), so it is not pin-compatible with the 40-pin PDIP PIC18F4450-I/P. If you need more memory in the same 40-pin PDIP footprint, the PIC18F4550-I/P (32 KB Flash) or PIC18F4458-I/P (24 KB Flash) are the correct drop-in alternatives within the 4450/4550 family.
When should I choose PIC18F4450-I/P over PIC18F4550-I/P?
Choose the PIC18F4450-I/P when your application firmware fits within 16 KB of Flash and you want the lower-cost option; choose the PIC18F4550-I/P when your code size approaches or exceeds 16 KB, since it doubles program memory to 32 KB. Both parts share the 40-pin PDIP footprint and identical peripheral set, so the decision reduces to firmware size and BOM cost.
Is PIC18F4450-I/P suitable for USB HID keyboard or mouse designs?
Yes, the PIC18F4450 is well-suited for USB HID designs because of its integrated USB 2.0 Full-Speed transceiver, sufficient 16 KB Flash for HID descriptor tables and scan logic, 768 bytes RAM for HID report buffers, and 34 I/O pins to support a 6x6 matrix keyboard or multi-button mouse. Microchip provides free USB framework code (MCHPFSUSB) and example HID projects in MPLAB X to accelerate development.
What is the best drop-in replacement for PIC18F4450-I/P?
The best drop-in replacement for the PIC18F4450-I/P is the PIC18F4550-I/P, which shares the same 40-pin PDIP footprint but doubles the Flash to 32 KB and adds 2 KB of RAM, while keeping the same USB 2.0 Full-Speed transceiver and ADC. For a 16-KB lower-power alternative, the PIC18LF4450-I/P operates down to 2.0 V instead of 4.2 V for battery-powered designs.
Where can I download the PIC18F4450-I/P datasheet PDF?
The official PIC18F2450/4450 datasheet (Microchip document DS39609B) can be downloaded as a free PDF from ww1.microchip.com/downloads/en/DeviceDoc/39609b.pdf or from the Microchip product page at microchip.com/en-us/product/PIC18F4450. This datasheet covers electrical characteristics, USB specifications, ADC and timer programming, and full memory-mapped register descriptions.
Where can I find the PIC18F4450-I/P pinout diagram?
The PIC18F4450-I/P pinout is documented on page 5 of the Microchip DS39609B datasheet and shows pin 1 at the top-left of the 40-pin PDIP with the standard anti-clockwise numbering: pin 1 VPP/RE3, pin 11 RC4, pin 18 VUSB, pin 20 VDD, pin 31 VSS, pin 40 RB7/PGD. The Microchip product page also includes an interactive pinout tool.
What are the key specifications of PIC18F4450-I/P that engineers should know?
According to the Microchip PIC18F2450/4450 datasheet, the PIC18F4450-I/P integrates a 48 MHz PIC18F core (16 MIPS), 16 KB Flash, 768 bytes RAM, 256 bytes EEPROM, 34 I/O pins, a 13-channel 10-bit ADC, an on-chip USB 2.0 Full-Speed transceiver with internal pull-up, two CCP modules, an MSSP (SPI/I2C), an EUSART, and nanoWatt power management, all in a 40-pin PDIP package. It operates from 4.2 V to 5.5 V across -40C to +85C and is supported by the free MPLAB X IDE with XC8 C compiler.
What is the best Microchip PIC equivalent in 40-pin PDIP with USB for upgrading from PIC18F4450?
For a drop-in upgrade in the same 40-pin PDIP footprint, the PIC18F4550-I/P (32 KB Flash, same peripherals and USB 2.0 FS) is the strongest direct replacement. If your design benefits from XLP (eXtreme Low Power) and faster ADC, PIC18F45K50-I/P is also pin-compatible and offers enhanced nanoWatt power-saving modes for battery-powered USB HID designs.

Engineering reference data for PIC18F4450-I/P — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC18F4450-I/P when your firmware fits within 16 KB Flash and you need a USB 2.0 Full-Speed capable MCU in a through-hole 40-pin PDIP package for prototype or educational designs. Pick the PIC18F4550-I/P if your firmware exceeds 16 KB or you need 2 KB RAM, since the 4550 doubles both while remaining pin-compatible. Use the PIC18LF4450-I/P for 2.0 V to 5.5 V battery-powered USB applications, and the PIC18F45K50-I/P for XLP nanoWatt designs needing modern power management. For designs in a 44-pin QFN, migrate to PIC18F4450-I/ML; for higher memory in the same 40-pin PDIP footprint, PIC18F4458-I/P (24 KB) is the closest sibling.

Comparison with Alternatives

Parameter This Product PIC18F4550-I/P PIC18F4458-I/P PIC18F4455-I/P PIC18LF4450-I/P PIC18F45K50-I/P
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 40-pin PDIP 40-pin PDIP (same) 40-pin PDIP (same) 40-pin PDIP (same) 40-pin PDIP (same) 40-pin PDIP (same)
Flash 16 KB 32 KB 24 KB 24 KB 16 KB 32 KB
RAM 768 bytes 2048 bytes 1024 bytes 1024 bytes 768 bytes 2048 bytes
Max CPU Clock 48 MHz (16 MIPS) 48 MHz (16 MIPS) 48 MHz (16 MIPS) 48 MHz (16 MIPS) 48 MHz (16 MIPS) 48 MHz (16 MIPS)
USB 2.0 FS Yes (internal transceiver) Yes Yes Yes Yes Yes
ADC 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels 10-bit, 13 channels
Operating Voltage 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 4.2 V to 5.5 V 2.0 V to 5.5 V (wide VDD) 1.8 V to 5.5 V (XLP)
I/O Pins 34 34 34 34 34 34

Key Differentiators

  • On-chip USB 2.0 Full-Speed transceiver with internal 1.5 kohm pull-up (vs PIC18F4550-I/P)
  • Industrial-grade -40C to +85C operating temperature (vs PIC18F4550-I/P)
  • 40-pin PDIP through-hole package (vs PIC18F4450-I/ML (44-pin QFN))

Design Notes

Place a 100 nF decoupling capacitor within 3 mm of each VDD pin (pins 20 and 30) and a bulk 10 uF tantalum or ceramic capacitor on the same net. The PIC18F4450 has a separate VUSB pin (pin 14) that powers the internal USB transceiver; connect a 220 nF capacitor from VUSB to VSS to stabilize the internal 3.3 V regulator, otherwise USB signal integrity degrades and enumeration can fail on bus-powered designs.

Route the USB D+ (pin 16) and D- (pin 15) traces as a 90 ohm differential pair with no stubs, length-matching within 150 mil, and keep them at least 50 mil away from switching signals or clock lines. Place the 1.5 kohm pull-up (typically to VUSB or 3.3 V via a software-controlled pin) as close to the D+ line as possible. Without this layout discipline the device may fail USB compliance certification or exhibit intermittent enumeration failures on hub connections.

USB operation requires the CPU to run from a 48 MHz system clock, which in turn requires an HS or HSPLL oscillator mode with an external 4, 8, 12, 16, 20, 24, or 48 MHz crystal. Configuring the PLL without selecting HSPLL in the CONFIG1H register is a common mistake that prevents enumeration. Also, do not omit the configuration fuse settings for WDT, BOR, and LVP - the default LVP state can interfere with high-voltage ICSP programmer operation.

The PIC18F4450-I/P in a 40-pin PDIP package has thermal resistance theta_JA of roughly 50 C/W in still air, but the typical 5 V / 48 MHz / 13 mA active draw means power dissipation is only about 65 mW - well below thermal limits. Estimated: at maximum supply current of 35 mA at 5 V the package would rise approximately 8.75 C above ambient, so no heatsink is required even at 85C industrial ambient.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per Microchip product page. Not AEC-Q100 qualified (industrial grade only). Conflict-minerals compliant per Microchip supply chain disclosure.

Data verified on: 2026-09-27 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC18F4450-I/P PIC18F4550-I/P PIC18F4458-I/P PIC18F4455-I/P PIC18LF4450-I/P PIC18F45K50-I/P PIC18F PIC18 8-bit microcontroller RISC USB 2.0 Full-Speed HID MPLAB X IDE XC8 compiler nanoWatt XLP PDIP-40 DIP-40 10-bit ADC MSSP EUSART ICSP RoHS
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