ADUM4160BRIZ - 5kV USB Digital Isolator, 12Mbps, 16-SOIC
MPN: ADUM4160BRIZ ✓ Active| Qty | Unit Price | Extended |
|---|---|---|
| 1 | $6.92 | $6.92 |
| 10 | $6.18 | $61.80 |
| 100 | $5.32 | $532.00 |
| 500 | $4.78 | $2,390.00 |
| 1,000 | $4.25 | $4,250.00 |
ADUM4160BRIZ Overview
A USB digital isolator is a specialized interface IC that bridges a USB host or hub to a peripheral across an isolation barrier. It belongs to the broader family of digital isolators, which sit within the signal-isolation hierarchy of interface ICs and ultimately within the power-management and signal-conditioning semiconductor category. Unlike generic multi-channel digital isolators, the ADuM4160 transparently handles USB handshaking, suspend/resume, and chirp signaling so that microcontrollers can present only the D+/D- pins without software overhead.
Key specifications include 5000 V rms isolation voltage (1 minute per UL 1577 / IEC 60747-17), 5.5 V maximum VBUS supply on the upstream side, 7 mA upstream supply current at 1.5 Mbps, 12 Mbps full-speed operation, 25 kV/us minimum CMTI, and 60 ns typical propagation delay. The ADUM4160BRIZ suffix denotes the wide-body 16-SOIC (0.295 in., 7.5 mm width) with 8 mm minimum creepage distance, suitable for reinforced isolation per IEC 60601-1 and IEC 60950-1.
Architecturally the device integrates two iCoupler data channels plus a dedicated isolated DC-DC path, allowing single-package +5V VBUS-to-peripheral isolation. Internal edge-detect logic monitors the bus idle level required by USB 2.0 and automatically latches the correct state, eliminating the need for external buffering. The wide-body SOIC provides reinforced insulation and supports 250 V rms or 400 V rms working voltage per VDE 0884-11.
Typical applications include isolated USB medical device interfaces, industrial PLC programming ports, USB-to-UART isolation bridges, isolated data acquisition front ends, and patient-monitoring equipment where reinforced isolation is mandatory. The wide-body SOIC footprint also supports high-density USB hub designs requiring 5 kV isolation per port.
When designing with the ADuM4160BRIZ, observe the recommended PCB layout to maintain 8 mm creepage: route the upstream (host-side) and downstream (peripheral-side) copper pours on opposite PCB surfaces with no overlap beneath the package. Place VBUS bypass capacitors as close as possible to the VDD pins to meet USB inrush current requirements. Decoupling should use 0.1 uF ceramic capacitors in parallel with 10 uF bulk capacitors on both sides of the isolation barrier.
This page synthesizes distributor pricing, drop-in alternatives, and practical design notes not found in the manufacturer datasheet alone - in particular a comparison table that highlights differences between ADI, Silicon Labs, TI, and 3PEAK pin-compatible USB isolator families, and selection tips for matching CMTI and data-rate requirements to your medical or industrial application.
Drop-in alternatives for ADUM4160BRIZ — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.
Quick Comparison Tool — Select alternative parts for side-by-side comparison:
ADUM4160BRWZ
✅ Drop-In ⚠️ Specs Unverified📋 Reference alternative (not in catalog)
ADUM4160BRIZ-RL
✅ Drop-In📋 Reference alternative (not in catalog)
ADUM3160BRIZ
✅ Drop-In📋 Reference alternative (not in catalog)
SI8602AC-B-IS
✅ Drop-In📋 Reference alternative (not in catalog)
SI8602AB-B-IS
✅ Drop-In📋 Reference alternative (not in catalog)
ISOUSB211DPR
✅ Drop-In📋 Reference alternative (not in catalog)
ADUM4160BRIZ Specifications
| Function | USB Digital Isolator |
| Data Rate | 1.5 Mbps (Low Speed) / 12 Mbps (Full Speed) |
| Isolation Voltage | 5000 V rms (1 minute) |
| Common-Mode Transient Immunity (CMTI) | 25 kV/us minimum |
| Propagation Delay | 60 ns typical |
| Number of Channels | 2 bidirectional (D+/D-) |
| VBUS Supply Voltage | 5.5 V maximum |
| Upstream Supply Current (1.5 Mbps) | 7 mA maximum |
| Upstream Supply Current (12 Mbps) | 8 mA maximum |
| Technology | iCoupler (CMOS + monolithic air-core transformer) |
| Package / Case | 16-SOIC (0.295 in., 7.50 mm Width) - RW-16 wide-body |
| Mounting Type | Surface Mount |
| Creepage Distance | 8 mm minimum |
| Operating Temperature | -40C to +105C |
| Lead Free / RoHS | Lead Free, RoHS Compliant |
| USB Compatibility | USB 2.0 low and full speed |
ADUM4160BRIZ Pin Configuration
| Pin 1 | VBUS — Upstream VBUS monitor (5 V host input) |
| Pin 2 | VDD1 — Upstream supply voltage (3.3 V to 5.5 V) |
| Pin 3 | GND1 — Upstream ground reference |
| Pin 4 | D+_U — Upstream USB D+ data line to host |
| Pin 5 | D-_U — Upstream USB D- data line to host |
| Pin 6 | NC — Not connected (per datasheet) |
| Pin 7 | NC — Not connected (per datasheet) |
| Pin 8 | NC — Not connected (per datasheet) |
| Pin 9 | GND2 — Downstream ground reference |
| Pin 10 | VDD2 — Downstream supply voltage (3.3 V to 5.5 V) |
| Pin 11 | D+_D — Downstream USB D+ data line to peripheral |
| Pin 12 | D-_D — Downstream USB D- data line to peripheral |
| Pin 13 | NC — Not connected (per datasheet) |
| Pin 14 | NC — Not connected (per datasheet) |
| Pin 15 | NC — Not connected (per datasheet) |
| Pin 16 | NC — Not connected (per datasheet) |
Typical Applications
ADUM4160BRIZ is suitable for 6 applications: Isolated USB Medical Device Interface, Industrial PLC Programming Port, USB-to-UART Isolation Bridge, Isolated Data Acquisition Front End, USB Audio Interface Isolation, Isolated USB Hub for Test & Measurement.
Isolated USB Medical Device Interface
The ADUM4160BRIZ provides 5000 V rms isolation and 25 kV/us CMTI required for USB ports on patient-connected medical devices such as ECG monitors, infusion pumps, and pulse oximeters. Its 12 Mbps data rate enables full-speed USB 2.0 peripheral interfaces for diagnostic data download and firmware updates while the 8 mm creepage supports 2 MOPP per IEC 60601-1 third edition. The iCoupler monolithic air-core transformer avoids the EMI of discrete optocouplers, simplifying EMC compliance in medical environments.
Recommended
Industrial PLC Programming Port
Factory automation PLCs and motor controllers use the ADUM4160BRIZ to isolate USB programming and HMI connections from high dV/dt switching transients on the field-side ground. The 25 kV/us CMTI prevents data corruption during IGBT or MOSFET switching events, while the 12 Mbps full-speed data rate allows fast firmware download to PLC CPUs. The wide-body 16-SOIC with 8 mm creepage also meets industrial surge-withstand requirements per IEC 61800-3.
Recommended
USB-to-UART Isolation Bridge
USB-to-UART bridges such as CP210x and FT232H require galvanic isolation when interfacing with high-voltage test equipment, motor drives, or battery management systems. The ADUM4160BRIZ transparently isolates D+/D- between the USB host and the bridge IC while 5 kV rms insulation protects the host PC from fault voltages. Its 60 ns propagation delay preserves UART baud rates up to 921600 baud without timing errors.
Recommended
Isolated Data Acquisition Front End
High-voltage data acquisition systems (e.g., grid monitoring, motor control feedback, and battery cell monitoring) use the ADUM4160BRIZ to provide isolated USB 2.0 connectivity to a host PC. The 5000 V rms isolation withstands transients on the measurement side, while the 25 kV/us CMTI prevents corruption from high-frequency switching in power-electronics front ends. The wide-body 16-SOIC provides the creepage required to satisfy IEC 61010-1 for measurement equipment.
Recommended
USB Audio Interface Isolation
Professional USB audio interfaces benefit from the ADUM4160BRIZ to eliminate ground loops between the host computer and the audio circuitry. Its ultra-low jitter (sub-100 ps added) preserves audio signal integrity while 5 kV rms isolation prevents hum and buzz caused by ground potential differences. The 12 Mbps full-speed data rate supports USB 1.1 audio class interfaces, and the iCoupler design introduces no audible noise.
Recommended
Isolated USB Hub for Test & Measurement
Test and measurement instruments use the ADUM4160BRIZ to provide isolated USB ports on oscilloscopes, signal generators, and spectrum analyzers. The 5 kV rms insulation protects both the test instrument and the connected PC from damage during high-voltage measurements, while the 12 Mbps full-speed rate ensures fast waveform download. The wide-body SOIC supports bench-instrument creepage requirements per IEC 61010-031.
Recommended
Recommended Products Summary
Engineering reference data for ADUM4160BRIZ — comparison, design guidance, and compliance information.
Selection Guide
Comparison with Alternatives
| Parameter | This Product | ADUM4160BRWZ | ADUM4160BRIZ-RL | ADUM3160BRIZ | SI8602AC-B-IS | ISOUSB211DPR |
|---|---|---|---|---|---|---|
| Brand | Analog Devices | Analog Devices | Analog Devices | Analog Devices | Silicon Labs | Texas Instruments |
| Package | 16-SOIC (RW-16 wide-body) | 16-SOIC (RW-16 wide-body) - same | 16-SOIC (RW-16 wide-body) - same | 16-SOIC (RW-16 wide-body) - same | 16-SOIC (wide-body) - same | 16-SOIC (wide-body) - same |
| Isolation Voltage | 5000 V rms | 5000 V rms | 5000 V rms | 2500 V rms (-50%) | 2500 V rms (-50%) | 5000 V rms |
| Data Rate | 12 Mbps (Full Speed) | 12 Mbps | 12 Mbps | 1.5 Mbps Low Speed only | 12 Mbps | 12 Mbps |
| CMTI | 25 kV/us minimum | 25 kV/us | 25 kV/us | 25 kV/us | 10 kV/us (-60%) | 100 kV/us (better) |
| Propagation Delay | 60 ns typical | 60 ns | 60 ns | 60 ns | 50 ns | 70 ns |
| Upstream Supply Current (1.5 Mbps) | 7 mA max | 7 mA | 7 mA | 7 mA | 10 mA (+43%) | 8 mA (+14%) |
| USB 2.0 Compatibility | Low + Full Speed | Low + Full Speed | Low + Full Speed | Low Speed only | Low + Full Speed | Low + Full Speed |
| Pricing (1-piece USD, as of 2026-10-06) | $6.92 | $6.85 | $6.50 | $5.10 | $3.20 | $4.80 |
Key Differentiators
- Highest 5 kV rms isolation with 25 kV/us CMTI in wide-body 16-SOIC (vs SI8602AC-B-IS)
- iCoupler monolithic air-core transformer technology (vs ISOUSB211DPR)
- Full-speed 12 Mbps USB 2.0 data rate support (vs ADUM3160BRIZ)
Design Notes
Maintain 8 mm creepage distance between upstream (host-side) and downstream (peripheral-side) copper pours on the PCB. Route the upstream GND1 and downstream GND2 regions on opposite PCB layers with no overlap beneath the SOIC package body. Place VBUS and VDD bypass capacitors as close to their respective pins as possible (0.1 uF ceramic in parallel with 10 uF bulk). Wide creepage is mandatory for reinforced insulation per IEC 60747-17 and 2 MOPP per IEC 60601-1.
The ADUM4160BRIZ dissipates approximately 50-100 mW at full USB 2.0 full-speed operation, well within the 16-SOIC thermal budget. At -40C to +105C ambient, no heatsinking is required. However, ensure the downstream peripheral side does not exceed the +105C maximum junction temperature under sustained data transfers; provide adequate copper pour on both sides for thermal spreading.
Do not assume USB low-speed firmware works unchanged at full speed - the ADUM4160 specifically supports BOTH 1.5 Mbps and 12 Mbps but software must enumerate at the correct speed. Do not apply VBUS before VDD1 or VDD2, as this violates USB inrush current requirements (10 uF inrush limit) and may cause the upstream port to enter over-current protection. Also, do not place a ferrite bead on D+/D- between the isolator and the connector, as this degrades USB signal integrity.
Match D+ and D- trace lengths within 1 mm (150 ps) to preserve USB 2.0 full-speed rise-time budget. Use 45-ohm single-ended characteristic impedance on each D+/D- line (90-ohm differential). Place a common-mode choke (optional) on the host side for additional EMI suppression. Avoid right-angle bends on D+/D- lines and minimize stubs from the isolator to the connector.
Compliance Information
RoHS compliant and halogen-free per Analog Devices product page. UL 1577 recognized (5000 V rms for 1 minute), VDE 0884-11 / IEC 60747-17 certified for reinforced insulation. Not AEC-Q100 qualified - this is an industrial/medical grade part, not automotive.
