Microchip Technology

ATSAM4S16CA-AN - Cortex-M4 120MHz 1MB Flash MCU | Microchip

MPN: ATSAM4S16CA-AN βœ“ Active
In Stock Ships in 1-3 business days
1.62 V to 3.6 V Vdss 100-LQFP (14x14 mm), Green Package 120 MHz Speed 1024 KB (dual-bank, ECC) Memory
From $2.61 USD / Unit
MOQ: 1 |
Price updated: 2026-09-20
Volume Pricing
Qty Unit Price Extended
1 $3.36 $3.36
10 $3.19 $31.90
100 $2.95 $295.00
500 $2.79 $1,395.00
1,000 $2.61 $2,610.00
ℹ️ All prices are in USD

ATSAM4S16CA-AN Overview

The Microchip Technology ATSAM4S16CA-AN is a 32-bit ARM Cortex-M4 microcontroller running at up to 120 MHz, with 1024 Kbytes dual-bank embedded Flash and 128 Kbytes SRAM, housed in a 100-pin LQFP Green (AN) package.

A microcontroller (MCU) integrates a processor core, memory, and peripherals onto a single chip, sitting at the device level of the embedded-systems hierarchy between discrete logic and full application processors. The SAM4S series belongs to the ARM Cortex-M4 family of 32-bit microcontrollers, which combine general-purpose MCU control capability with DSP instructions and Thumb-2 technology for efficient signal processing.

Key features include the Cortex-M4 core with a Memory Protection Unit (MPU), DSP instruction support, dual-bank Flash with ECC, Security Bit and Flash lock protection, plus rich connectivity: EBI/EMI external bus, I2C, IrDA, memory card interface, SPI, SSC, UART/USART, and USB. Peripheral support covers brown-out detect/reset, DMA, POR, PWM, and a watchdog timer, with 79 general-purpose I/O lines.

The dual-bank Flash architecture enables safe in-field firmware updates: the device can execute from one bank while erasing or programming the other, reducing boot-loader downtime risk. ECC on Flash improves reliability in electrically noisy industrial environments. The SAM4S series operates from 1.62V to 3.6V and is pin-to-pin compatible with the SAM7S, SAM3N, SAM3S, and SAM4N families, providing a clear migration path from legacy designs.

Typical applications include industrial control, consumer products, and PC peripherals, as well as USB-equipped field devices, motor-control systems using PWM outputs, and data-acquisition nodes using the SSC and memory card interfaces.

Design considerations: operate within the 1.62V to 3.6V supply range, budget the 79 available I/O against the EBI external memory bus requirements, and plan the dual-bank Flash layout early to take full advantage of ECC and safe update capability.

This page synthesizes distributor pricing, verified drop-in alternatives, and practical design notes not found in the manufacturer datasheet, with data verified as of 2026-09-20.

Drop-in alternatives for ATSAM4S16CA-AN β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ATSAM4S16CA-AN (same form factor and footprint) β€” differing in Package, Series, Core Size, Instruction Set, Flash Memory.

Microchip Technology
Package: 100-TFBGA (9x9 mm)
Series: SAM4E
Instruction Set: Thumb-2
Compare with ATSAM4S16CA-AN β†’
Microchip Technology
Package: 100-VFBGA (7x7 mm)
Series: SAM4N
Core Size: 32-Bit Single-Core
Compare with ATSAM4S16CA-AN β†’

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

ATSAM4S16CB-ANR

βœ… Drop-In
πŸ“¦ LQFP-100
same SAM4S family, same 100LQFP, same 1MB Flash; SRAM configuration and peripheral allocation differ slightly within family

πŸ“‹ Reference alternative (not in catalog)

ATSAM4E16CA-ANR

βœ… Drop-In
πŸ“¦ LQFP-100
same 100-pin LQFP and Cortex-M4 120MHz 1MB Flash core; SAM4E adds Ethernet MAC and CAN, pin map shared

πŸ“‹ Reference alternative (not in catalog)

ATSAM4E16CB-CN

βœ… Drop-In
Microchip Technology
πŸ“¦ LQFP-100
ARM Cortex-M4 with 2 Kbytes Cache Β· 32-Bit Β· 120 MHz Β· 1 MB (1M x 8) Β· Thumb-2 Β· Yes Β· Yes Β· Yes

βœ“ In Stock

$3.79 / Unit

View Datasheet β†’

ATSAM4N16CA-CFUR

βœ… Drop-In
Microchip Technology
πŸ“¦ LQFP-100
ARM Cortex-M4 Β· 32-Bit Single-Core Β· 100 MHz Β· 1 MB (1M x 8) Β· 80 KB Β· 1.62 V to 3.6 V Β· Thumb-2, DSP instructions Β· Yes (MPU)

βœ“ In Stock

$4.95 / Unit

View Datasheet β†’

ATSAM4S16CA-AN Maximum Ratings & Electrical Characteristics

Core Processor ARM Cortex-M4
Core Size 32-bit
Maximum Clock Speed 120 MHz
Flash Memory 1024 KB (dual-bank, ECC)
SRAM 128 KB
Supply Voltage Range 1.62 V to 3.6 V
Number of I/O 79
Connectivity EBI/EMI, I2C, IrDA, Memory Card, SPI, SSC, UART/USART, USB
Peripherals Brown-out Detect/Reset, DMA, POR, PWM, WDT
Instruction Set Thumb-2, DSP instructions
Memory Protection MPU (Memory Protection Unit)
Flash Security Security Bit, Flash lock
Pin-to-Pin Compatibility SAM7S, SAM3N, SAM3S, SAM4N families
Package 100-LQFP (14x14 mm), Green
Mounting Type Surface Mount
Part Status Active
Series SAM4S

ATSAM4S16CA-AN 100-lqfp (14x14 mm), green Pin Configuration Guide

Pin configuration for ATSAM4S16CA-AN (100-lqfp (14x14 mm), green package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

100-lqfp (14x14 mm), green package pinout diagram for ATSAM4S16CA-AN

No detailed pinout data available for ATSAM4S16CA-AN.

Refer to the datasheet for full pin configuration.

Typical Applications

ATSAM4S16CA-AN is suitable for 6 applications: Industrial Control Systems, USB Peripheral Devices, Consumer Electronics, Data Acquisition and Logging, Motor Control and Actuation, Legacy SAM7S/SAM3S Migration and PC Peripherals.

🏭

Industrial Control Systems

The ATSAM4S16CA-AN fits industrial control applications through its combination of a 120 MHz Cortex-M4 core, watchdog timer, brown-out detect/reset, and ECC-protected 1 MB dual-bank Flash. ECC corrects single-bit Flash errors, improving reliability in electrically noisy factory environments, while the wide 1.62V to 3.6V supply range tolerates poorly regulated industrial power rails. PWM channels drive actuators and motor drivers, DMA offloads data movement to keep CPU cycles free for control loops, and 79 GPIO lines interface PLC-style I/O modules. Using SPI and UART/USART links to sensor and communication modules, a typical control node maintains deterministic loop performance; Microchip lists industrial control as a primary SAM4S application, and the pin-compatible SAM3S/SAM4N migration path simplifies long-term product family maintenance.

πŸ–₯️

USB Peripheral Devices

With an integrated USB peripheral and 120 MHz Cortex-M4 performance, the ATSAM4S16CA-AN is well matched to PC peripheral and USB instrument designs. The USB interface enumerates as a device to a host PC while the SSC and SPI interfaces acquire data from codecs or ADC front ends; DMA keeps USB transfers serviced without CPU intervention, sustaining throughput alongside real-time processing. The dual-bank Flash enables in-field firmware updates over USB - the device reprograms one bank while executing from the other, avoiding boot-loader dead time. Per Microchip, PC peripherals are an explicit SAM4S target application. Designers should budget 3.3V for VDDUSB per the 1.62V to 3.6V supply specification and verify USB compliance using Microchip's SAM4S evaluation kit and software package.

πŸ“±

Consumer Electronics

The SAM4S series is explicitly positioned by Microchip for consumer applications, and the ATSAM4S16CA-AN suits them because it balances performance and cost: a 120 MHz Cortex-M4 with DSP instructions handles audio processing, user-interface graphics updates, and sensor fusion in a single 100-pin LQFP priced from roughly $3.36 (as of 2026-09-20). The 1 MB Flash accommodates feature-rich firmware without external code storage, while memory card interfaces support removable storage in products such as portable audio players and small appliances. Operating from a 3.3V rail typical of consumer designs, the device consumes power efficiently with DMA-driven sleep-mode workflows. The wide temperature-tolerant supply range also supports battery-powered designs regulated by simple LDOs or buck converters, minimizing bill-of-materials cost.

πŸ”§

Data Acquisition and Logging

For data-acquisition nodes, the ATSAM4S16CA-AN offers the memory card interface, SSC serial audio/telecom port, multiple UART/USART channels, and 1 MB internal Flash for local storage - no external memory is required for moderate logging workloads. ADC sampling results can be streamed by DMA into SRAM while the Cortex-M4 applies DSP filtering, and completed records are written to SD-class media through the memory card interface. EBI/EMI external bus support allows SRAM or parallel-flash expansion when datasets exceed the 128 KB internal SRAM, and the ECC on Flash protects logged configuration and calibration data against bit corruption. This combination makes the part suitable for environmental loggers, metering equipment, and industrial recorders that must run unattended for long periods with a watchdog supervising operation.

βš™οΈ

Motor Control and Actuation

The ATSAM4S16CA-AN supports motor control through its PWM peripherals, high-speed 120 MHz Cortex-M4 core with DSP instructions, and DMA-assisted control loop timing. PWM outputs drive MOSFET gate drivers or power stages for brushed DC, stepper, and light BLDC applications, while the ADC-interfaced feedback path is handled by the CPU's DSP multiply-accumulate instructions for efficient PI and filtering algorithms. Brown-out detect/reset and the watchdog timer ensure safe recovery from supply dips - important when switching loads share the same rail. With 79 I/O lines, position sensors, limit switches, and communication to a supervisory controller over UART or SPI all connect without external glue logic. Designers should follow Microchip SAM4S evaluation kit reference layouts for PWM and analog grounding to minimize switching noise coupling into measurement paths.

🧩

Legacy SAM7S/SAM3S Migration and PC Peripherals

Per Microchip's SAM4S datasheet, the ATSAM4S16CA-AN is pin-to-pin compatible with SAM7S, SAM3S, SAM3N, and SAM4N devices, making it the recommended drop-in migration target for legacy designs approaching end-of-life. A board designed for SAM3S in LQFP-100 accepts the SAM4S without layout change, while firmware gains a 120 MHz Cortex-M4 with DSP instructions, dual-bank Flash with ECC, and USB - typically a 4x performance uplift over SAM7S-class parts. The Thumb-2 instruction set and Microchip's software package ease code porting, and the SAM4S evaluation kit accelerates validation. For long-life industrial products, this compatibility path consolidates multiple legacy SKUs onto one modern platform, reducing qualification overhead while preserving the existing PCB investment and mechanical design.

Recommended Products Summary

What is the ATSAM4S16CA-AN microcontroller?
The ATSAM4S16CA-AN is a 32-bit ARM Cortex-M4 microcontroller from Microchip Technology running at up to 120 MHz. It integrates 1024 KB of dual-bank embedded Flash with ECC, 128 KB of SRAM, and peripherals including USB, SPI, I2C, SSC, UART/USART, and PWM, packaged in a 100-pin LQFP Green (AN) package. Per the SAM4S family datasheet (60001419B), it targets consumer, industrial control, and PC peripheral applications.
What is the price of ATSAM4S16CA-AN?
The ATSAM4S16CA-AN is priced from approximately $3.358 at LCSC as of 2026-09-20, with unit prices around $7.93 quoted at some brokers such as Heisener. XAIPART tier pricing starts at $3.36 for quantity 1, $3.19 at quantity 10, $2.95 at quantity 100, $2.79 at quantity 500, and $2.61 at quantity 1000. All prices are as of 2026-09-20 and subject to distributor stock and market conditions.
Where to buy ATSAM4S16CA-AN online?
You can buy ATSAM4S16CA-AN from XAIPART directly on this page, and it is also listed in stock at LCSC (over 7,500 units reported across brokers including Heisener), Mouser, and other distributors aggregating on Octopart. LCSC lists the part as in-stock with price from $3.358 as of 2026-09-20. For volume requirements, XAIPART supports quotation requests for quantities beyond 1000 units.
Is ATSAM4S16CA-AN in stock?
Yes, the ATSAM4S16CA-AN is reported in stock at multiple distributors. Heisener lists 7,568 pieces in inventory, and LCSC lists the part as in-stock as of 2026-09-20. Octopart aggregates availability from 10 distributors. Availability changes frequently, so confirm current stock on the XAIPART product page or with the distributor before placing a large order; lead time is listed as 'to be confirmed' by some brokers.
What is the difference between ATSAM4S16CA-AN and ATSAM4S16CA-CU?
The difference is the package: the ATSAM4S16CA-AN uses a 100-pin LQFP with gull-wing leads, while the ATSAM4S16CA-CU uses a 100-ball TFBGA (9x9 mm) package. Both share the same Cortex-M4 core, 120 MHz speed, 1 MB Flash, and identical peripheral set. Because the packages differ, they are not drop-in replacements for each other; the LQFP-AN suits hand assembly and rework, while the BGA-CU saves board area.
What is the best drop-in replacement for ATSAM4S16CA-AN?
The closest drop-in replacement is ATSAM4S16CB-ANR in the same 100-pin LQFP package, differing only in SRAM configuration within the SAM4S family. ATSAM4N16CA in LQFP-100 is also pin-compatible but lacks the USB peripheral and some connectivity of the SAM4S. Per the Microchip SAM4S datasheet, the series is pin-to-pin compatible with SAM3S, SAM3N, SAM4N, and SAM7S 100-pin devices, enabling footprint-preserving migration. Verify USB requirement before substituting.
Is ATSAM4S16CA-AN suitable for industrial control applications?
Yes, the ATSAM4S16CA-AN is well suited to industrial control. Per Microchip, the SAM4S series explicitly targets industrial control among its primary applications. The device provides brown-out detect/reset, watchdog timer, and ECC on its 1 MB dual-bank Flash, which improves reliability in electrically noisy environments. The 120 MHz Cortex-M4 with DSP instructions handles real-time control loops, while PWM, DMA, and 79 I/O lines support actuator and sensor interfacing. The wide 1.62V to 3.6V supply range adds power-supply design margin.
When should I choose ATSAM4S16CA-AN over ATSAM4E16CA?
Choose the ATSAM4S16CA-AN when your design needs only standard connectivity (USB device, SPI, UART, I2C) and you want the simplest, lowest-power SAM4 platform. Choose the ATSAM4E16CA when you need an Ethernet MAC, CAN bus, or floating-point-extended peripherals, as the SAM4E adds those features in the same 100-pin LQFP-100 footprint. Both run a Cortex-M4 at 120 MHz with 1 MB Flash, so the decision hinges on networking features versus cost, not raw compute performance.
What is the best Microchip equivalent for ATSAM4S16CA-AN from another manufacturer?
A commonly considered cross-brand equivalent is the STMicroelectronics STM32F4 series in LQFP-100 (for example STM32F407VET6), which also pairs a Cortex-M4 with 1 MB-class Flash at similar clock speeds. However, these parts are NOT pin-to-pin compatible - peripheral multiplexing and pin maps differ, so a firmware and board redesign is required. Within verified web data for this part, no cross-brand pin-compatible drop-in equivalent exists; pin-compatible alternatives are limited to Microchip SAM3S/SAM4N/SAM4S family members in LQFP-100.
Where to download the ATSAM4S16CA-AN datasheet PDF?
The authoritative document is the SAM4S Microcontroller Family datasheet from Microchip, available at ww1.microchip.com/downloads/en/DeviceDoc/60001419B.pdf. This family document covers the ATSAM4S16CA and all SAM4S variants including full electrical specifications, peripheral descriptions, and package mechanical drawings for the 100-pin LQFP. Third-party mirrors exist (digchip.com, datasheets.com), but always prefer the Microchip official document to ensure the latest revision is used.
How many I/O pins does the ATSAM4S16CA-AN have?
The ATSAM4S16CA-AN provides 79 general-purpose I/O lines in its 100-pin LQFP package, according to the verified specifications for this part. The remaining pins are allocated to power (VDDCORE, VDDIO, VDDUSB, VDDIN), ground, analog functions, and the optional EBI/EMI external bus interface. When the external memory bus is enabled, a portion of the GPIO lines is multiplexed away, so budget I/O early in the design if you plan external memory expansion via EBI.
Can ATSAM4S16CA-AN be replaced by ATSAM4N16CA?
Yes, the ATSAM4N16CA is pin-to-pin compatible with the SAM4S in the 100-pin package, per the Microchip SAM4S family datasheet, but it is only a partial substitute: the SAM4N omits the USB peripheral and some connectivity found on the SAM4S. If your application does not use USB and needs the same 1 MB Flash and 120 MHz Cortex-M4 core, the SAM4N16CA works as a drop-in on the same PCB. If USB is used, stay within the SAM4S family such as the ATSAM4S16CB.
Is ATSAM4S16CA-AN the same as ATSAM4S16CB?
No, the ATSAM4S16CA and ATSAM4S16CB are not identical, although they are very close: both are SAM4S Cortex-M4 devices at 120 MHz with 1 MB Flash in the same 100-pin LQFP footprint. They differ in SRAM configuration and peripheral allocation within the family. Per the Microchip family datasheet, both belong to the same pin-to-pin compatible SAM4S series, so PCB footprint is shared, but firmware and memory maps should be re-validated when migrating between the CA and CB variants.
What are the key specifications of ATSAM4S16CA-AN that engineers should know?
Key specifications of the ATSAM4S16CA-AN: ARM Cortex-M4 32-bit core at up to 120 MHz; 1024 KB dual-bank embedded Flash with ECC, Security Bit, and lock; supply voltage 1.62 V to 3.6 V; 79 general-purpose I/O; connectivity including EBI/EMI, I2C, IrDA, memory card, SPI, SSC, UART/USART, and USB; peripherals including DMA, PWM, watchdog, brown-out detect/reset, and POR; MPU for memory protection; and a 100-pin LQFP Green package. Per Microchip, it is pin-to-pin compatible with SAM7S, SAM3N, SAM3S, and SAM4N 100-pin devices.
Is ATSAM4S16CA-AN RoHS compliant?
The ATSAM4S16CA-AN uses the 'AN' Green package suffix, indicating a RoHS-compliant, lead-free green package per Microchip's standard package nomenclature. Distributor listings such as Mouser describe it as an LQFP GREEN part. Exact REACH, halogen-free, and conflict-minerals declarations should be confirmed from Microchip's official product compliance page for the specific date code purchased, as compliance documentation is maintained per-batch by the manufacturer rather than in the datasheet.
What is the lead time for ATSAM4S16CA-AN?
Lead time for the ATSAM4S16CA-AN is listed as 'to be confirmed' at some brokers such as Heisener, while in-stock distributors like LCSC and Mouser can ship stock parts immediately - LCSC reports the item in stock as of 2026-09-20 with over 7,500 pieces available across broker inventory. For production volumes, standard Microchip lead times for active MCUs typically range from several weeks to a few months depending on allocation; contact XAIPART for a current quotation with confirmed delivery dates.

Engineering reference data for ATSAM4S16CA-AN β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the ATSAM4S16CA-AN when you need a 120 MHz Cortex-M4 with 1 MB dual-bank ECC Flash, USB device connectivity, and the safety of a broad pin-compatible family - ideal for industrial control, USB peripherals, and SAM7S/SAM3S legacy migrations in the 100-pin LQFP footprint. Choose ATSAM4S16CB-ANR if your firmware benefits from a different SRAM allocation within the same family. Choose ATSAM4E16CA-ANR or ATSAM4E16CB-CN when Ethernet or CAN networking is required - same footprint and core performance, added connectivity. Choose ATSAM4N16CA-CFUR only when USB is definitively unused and cost must be minimized, accepting loss of USB. Do not cross to STMicroelectronics or other vendors' LQFP-100 Cortex-M4 parts without board redesign: verified web data shows no cross-brand pin-compatible drop-in equivalent for this device. All prices as of 2026-09-20.

Comparison with Alternatives

Parameter This Product ATSAM4S16CB-ANR ATSAM4E16CA-ANR ATSAM4E16CB-CN ATSAM4N16CA-CFUR
Package 100-LQFP (AN, Green) 100-LQFP - same footprint 100-LQFP - same footprint 100-LQFP - same footprint 100-LQFP - same footprint
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Core ARM Cortex-M4 @ 120 MHz ARM Cortex-M4 @ 120 MHz ARM Cortex-M4 @ 120 MHz ARM Cortex-M4 @ 120 MHz ARM Cortex-M4 @ 120 MHz
Flash Memory 1024 KB dual-bank, ECC 1024 KB dual-bank, ECC 1024 KB 1024 KB 1024 KB
USB Yes Yes Yes Yes No
Ethernet / CAN No No Yes (SAM4E adds Ethernet MAC + CAN) Yes (SAM4E adds Ethernet MAC + CAN) No

Key Differentiators

  • Dual-bank Flash with ECC enables safe field firmware updates (vs ATSAM4N16CA-CFUR)
  • Same footprint with Ethernet/CAN upgrade path (vs ATSAM4E16CA-ANR)
  • Broadest family migration compatibility (vs ATSAM3S8BA-MUR)

Design Notes

Operate the ATSAM4S16CA-AN within its specified 1.62V to 3.6V supply range; the typical design point is a clean 3.3V rail. Decouple each VDDIO group and VDDCORE with 100 nF ceramic capacitors placed within 2 mm of the pins, plus bulk 10 uF per rail. Ensure brown-out reset is enabled in firmware so supply dips during inrush of attached peripherals do not corrupt Flash - critical when using the dual-bank update feature.

For the 100-pin LQFP (0.5 mm pitch), route the EBI/EMI external bus with length-matched traces if external memory is used, and keep USB D+/D- as a 90-ohm differential pair without stubs. Use a solid ground plane under the MCU and place crystal and decoupling capacitors before committing to fanout. Estimate: a 14x14 mm LQFP-100 with 2 internal layers is sufficient for most designs; add dedicated analog ground regions when ADC accuracy matters.

Do not assume full GPIO availability when using the EBI/EMI bus - data/address lines multiplex away a significant share of the 79 I/O. Plan the dual-bank Flash partition (application vs update bank) at project start, since ECC and Security Bit settings are not trivially changed later. When migrating from SAM3S/SAM7S, re-verify peripheral multiplexing per pin, as the shared footprint does not guarantee identical alternate-function mapping.

Estimated: at 120 MHz with all peripherals active, SAM4S-class devices draw in the tens of mA, so junction dissipation stays well below 0.5 W. With an LQFP-100 theta_JA typically near 50 C/W on a standard 4-layer board, temperature rise is under 25 C at 25 C ambient - no heatsink needed. Verify with your own measured current at maximum clock in your firmware configuration.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Unknown

AN suffix denotes Microchip Green (RoHS, lead-free) LQFP package per Mouser listing ('LQFPGREENEXT'). REACH and conflict-minerals declarations should be confirmed on Microchip's official compliance documentation.

Data verified on: 2026-09-20 β€” data verified and curated by XAIPART's component engineering team

Related Searches

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Related Components & Terms

Microchip Technology ATSAM4S16CA-AN ATSAM4S16CB-ANR ATSAM4E16CA-ANR ATSAM4E16CB-CN ATSAM4N16CA-CFUR ATSAM3S8BA-MUR ARM Cortex-M4 SAM4S series SAM3S SAM4N SAM7S microcontroller LQFP-100 dual-bank Flash ECC Memory Protection Unit MPU DSP instructions Thumb-2 RoHS EBI/EMI USB peripheral DMA PWM industrial control
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