Texas Instruments

INA116PA - 3fA Ultra Low Bias Current In-Amp | TI

MPN: INA116PA βœ“ Active
In Stock Ships in 1-3 business days
2 mV Vdss 3 fA at 25C Id 16-PDIP (N) Package
From $28.04 USD / Unit
MOQ: 1 |
Price updated: 2026-09-12
Volume Pricing
Qty Unit Price Extended
1 $35.05 $35.05
10 $33.3 $333.00
100 $31.55 $3,155.00
500 $29.79 $14,895.00
1,000 $28.04 $28,040.00
ℹ️ All prices are in USD

Drop-in alternatives for INA116PA β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

INA116PAG4

βœ… Drop-In
πŸ“¦ 16-PDIP (N)
Identical INA116 die, pinout, and specs (3 fA bias, 2 mV offset, gain 1-1000); G4 suffix is a packing designation only

πŸ“‹ Reference alternative (not in catalog)

INA116PAG4

βœ… Drop-In
πŸ“¦ 16-PDIP (N)
Same PDIP-16 INA116 device distributed via Rochester Electronics (DigiKey Marketplace listing), identical electrical parameters; alternate sourcing channel for continuity of supply

πŸ“‹ Reference alternative (not in catalog)

INA116PA Maximum Ratings & Electrical Characteristics

Amplifier Type Instrumentation Amplifier
Number of Channels 1
Input Bias Current (typ) 3 fA at 25C
Input Bias Current (at 85C) 25 fA
Input Offset Voltage (max) 2 mV
Gain Range 1 V/V to 1000 V/V
CMRR (min) 86 dB
Input Noise Density at 1 kHz 28 nV/sqrt(Hz)
Quiescent Current 1 mA
Supply Voltage Range (single) 9 V to 36 V
Supply Voltage Range (dual) +/-4.5 V to +/-18 V
Input Technology Difet FET with buffered guard drive
Input Overvoltage Protection Yes
Operating Temperature Range -40C to +85C
Package 16-PDIP (N)
Mounting Type Through Hole

INA116PA 16-pdip (n) Pin Configuration Guide

Complete pinout information for INA116PA (16-pdip (n) package). This analog component features input, output, and power supply pins. Refer to the manufacturer datasheet for offset null, compensation, and enable pin configurations. Ideal for signal conditioning and amplifier circuits.

16-pdip (n) package pinout diagram for INA116PA

No detailed pinout data available for INA116PA.

Refer to the datasheet for full pin configuration.

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for INA116PA Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this component. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

INA116PA is suitable for 6 applications: Photodiode Current Measurement, pH and Chemical Sensor Interfaces, Ionization Chamber and Radiation Detection, Precision Transducer Signal Conditioning, Medical and Biomedical Instrumentation, Mass Spectrometry and Vacuum Gauge Readout.

πŸ’‘

Photodiode Current Measurement

The INA116PA is exceptionally well suited to photodiode front ends because its 3 fA typical input bias current at 25C contributes essentially zero error relative to nanoampere or picoampere photocurrents, preserving measurement linearity down to the detection floor. In a typical circuit, the photodiode feeds the inverting input, the amplifier output drives a transimpedance or gain network, and the buffered guard drive pin is routed as a guard ring around the summing node to bootstrap away PCB leakage. The 1 to 1000 V/V gain range lets one design cover optical power meters, chromatography detectors, and fluorescence readers. Unlike discrete FET front ends, the monolithic three-op-amp topology maintains 86 dB minimum CMRR without hand matching, and the 28 nV/sqrt(Hz) input noise at 1 kHz keeps small-signal resolution high across the -40C to +85C industrial range.

🧩

pH and Chemical Sensor Interfaces

Glass pH electrodes and similar electrochemical sensors present source impedances of hundreds of megaohms or more, a regime where the INA116PA's femtoampere input bias current is decisive: at 3 fA typical, bias-current error through a 1 GOhm electrode is microvolts or less, whereas a conventional in-amp drawing picoamperes would introduce hundreds of microvolts of error and electrode polarization. The differential input rejects ground-path common-mode noise in wet or industrial environments, and the 86 dB minimum CMRR suppresses mains interference. The buffered guard drive output is connected to a driven shield on the electrode cable, eliminating shield leakage and capacitance effects that would otherwise slow response and add noise. With gain set from 1 to 1000 V/V via one resistor and a +/-4.5 V to +/-18 V supply range matching standard analog rails, the part integrates cleanly into laboratory analyzers and environmental monitoring transmitters.

πŸ”§

Ionization Chamber and Radiation Detection

Ionization chambers used in radiation monitoring, smoke detection, and beam instrumentation produce currents in the picoampere range at extremely high source impedance, exactly matching the INA116PA design envelope. The Difet input stage with special guarding techniques yields 3 fA typical bias current at 25C and still only 25 fA at 85C, so chamber background currents are not corrupted by amplifier leakage even in elevated-temperature installations. The two buffered guard drive pins are used to guard both input nodes and chamber feedthroughs, a technique described in the TI datasheet application section, suppressing surface leakage that dominates fA-level systems. Input overvoltage protection guards against transient events, and the 1 mA quiescent current permits battery-powered portable survey instruments. The PDIP-16 through-hole package also supports hand rework and prototyping common in nuclear instrumentation development.

🏭

Precision Transducer Signal Conditioning

Bridge and differential transducers - load cells, pressure sensors, thermistor bridges - benefit from the INA116PA's differential topology, 2 mV maximum input offset, and gain programmability from 1 V/V to 1000 V/V with a single resistor. While bias-current headroom exceeds most bridge requirements, the femtoampere inputs allow very large bridge resistances (10 MOhm and above) without loading error, enabling low-power sensor designs where bridge current must be minimized. The 86 dB minimum CMRR rejects ground differentials in industrial wiring, and the 28 nV/sqrt(Hz) noise at 1 kHz supports resolution of small bridge outputs over 10 kHz measurement bandwidths. Supply operation from 9 V to 36 V total covers +/-12 V and +/-15 V industrial analog rails directly. Setting gain close to the sensor full-scale requirement with a precision resistor yields best offset-drift performance per the TI datasheet guidance.

πŸ’Š

Medical and Biomedical Instrumentation

Biopotential and biosensor acquisition - impedance plethysmography, high-impedance microelectrode buffers, ion-selective electrode arrays - requires amplifiers that do not load the biological source. The INA116PA's 3 fA input bias current ensures negligible electrode polarization and DC offset artifacts even through glass microelectrodes of 100 MOhm impedance, and its differential three-op-amp architecture with 86 dB minimum CMRR rejects mains common-mode interference inherent in clinical environments. Guard drive pins are connected to driven shields on electrode cables, reducing cable leakage and preserving signal bandwidth, a critical technique at fA input levels per the TI datasheet. Operation from +/-4.5 V supplies suits battery-powered portable medical devices, while the -40C to +85C rating covers sterilization-adjacent environments. Gain from 1 to 1000 V/V lets one amplifier design serve multiple electrode types across a product family.

πŸ”¬

Mass Spectrometry and Vacuum Gauge Readout

Faraday cup collectors, residual gas analyzer detectors, and hot/cold cathode vacuum gauge electrometers output femtoampere-to-picoampere currents at very high impedance, making the INA116PA a natural front-end choice. Its 3 fA typical input bias current approaches the detector floor itself, and the buffered guard pins allow complete guarding of the collector feedthrough and cabling, which the TI datasheet identifies as essential to realizing rated bias performance in system. The 28 nV/sqrt(Hz) input noise at 1 kHz and 86 dB minimum CMRR preserve dynamic range across decade-spanning pressure or ion-current measurements, with the 1 to 1000 V/V gain resistor allowing ranged autoranging designs. Input overvoltage protection withstands collector transients during filament events, and the 1 mA quiescent draw from 9 V to 36 V total supply integrates into rack-mounted instrument power schemes without thermal concerns.

Recommended Products Summary

REF5025 Precision voltage reference for measurement scaling Used in: Photodiode Current Measurement OPA2277 Precision op amp for post-amplification filtering Used in: Photodiode Current Measurement, Medical and Biomedical Instrumentation ADS1256 24-bit delta-sigma ADC for digitizing the amplified signal Used in: pH and Chemical Sensor Interfaces REF5040 Low-noise voltage reference for ADC scaling Used in: pH and Chemical Sensor Interfaces OPA128 Electrometer-grade op amp for TIA subcircuits Used in: Ionization Chamber and Radiation Detection, Mass Spectrometry and Vacuum Gauge Readout ISO124 Precision isolation amplifier for HV-side readout Used in: Ionization Chamber and Radiation Detection REF5050 Excitation reference for sensor bridge Used in: Precision Transducer Signal Conditioning OPA333 Zero-drift op amp for offset correction stage Used in: Precision Transducer Signal Conditioning ADS1298 Analog front end for biopotential digitization Used in: Medical and Biomedical Instrumentation DAC8563 DAC for instrument range-control and offset nulling Used in: Mass Spectrometry and Vacuum Gauge Readout
What is the input bias current of the INA116PA?
The INA116PA has a typical input bias current of only 3 fA at 25C, rising to about 25 fA at 85C. According to the TI INA116 datasheet, this femtoampere-level performance comes from Difet inputs combined with special guarding techniques and buffered guard drive pins that let you actively guard PCB leakage paths, making the part suitable for electrometer-grade, high source impedance applications such as photodiode and ion chamber front ends.
What is the gain range of the INA116PA instrumentation amplifier?
The INA116PA sets gain from 1 V/V to 1000 V/V using a single external resistor connected between the gain-set pins, per the TI datasheet. The classic three-op-amp topology means the gain resistor sets the first-stage differential gain while the second stage is fixed unity gain, so gain accuracy and drift depend mainly on the external resistor quality. Choose a low-drift, low-temperature-coefficient resistor for stable precision gain.
What supply voltage range does the INA116PA support?
The INA116PA operates from 9 V to 36 V total supply, which corresponds to +/-4.5 V to +/-18 V in dual-supply configurations. According to TI product documentation, quiescent current is only about 1 mA, so power dissipation is modest even at +/-18 V rails. This range covers common industrial analog rails such as +/-5 V, +/-12 V, and +/-15 V without modification.
What is the price of INA116PA?
The INA116PA is a premium precision part; LCSC lists it at approximately $35.05 per unit as of 2026-09-13. XAIPART tier pricing starts at $35.05 at qty 1 and drops to about $28.04 at qty 1000 as of 2026-09-13. Because this femtoampere instrumentation amplifier has limited second sources, pricing varies between distributors, so compare DigiKey, Mouser, and LCSC before placing volume orders.
Where to buy INA116PA online?
You can buy the INA116PA from authorized distributors including DigiKey (ships today per its listing), Mouser, LCSC, and TI.com directly. XAIPART also offers the part with tier pricing as of 2026-09-13. Because this is a specialized ultra-low-bias-current device, check stock status carefully; some distributors carry it in limited quantity, and lead times can extend when factory inventory is depleted.
Is the INA116PA in stock and what is the lead time?
DigiKey's listing states buy now, ships today, indicating stock availability as of the data retrieval date of 2026-09-13, and LCSC also shows the part in stock from $35.0518. Lead times beyond distributor stock depend on TI factory scheduling; for large volumes, request a quote from XAIPART or check TI.com product status. Always verify current stock at checkout because precision analog inventory moves quickly.
What is the best drop-in replacement for INA116PA?
The best same-footprint replacement is the INA116PAG4, which is the identical INA116 die in the same 16-pin PDIP (N) package - the G4 suffix denotes a packing designation, and the part is pin-to-pin and parametrically identical at 100%. According to FindIC's comparison, the INA116PAG4 shares the 3 fA bias current, Difet inputs, and guard pins. No cross-brand pin-compatible equivalent in PDIP-16 exists in verified web data, which is typical for this niche electrometer-grade part.
INA116PA vs INA116UA - what is the difference?
The INA116PA and INA116UA share the identical die and specifications - 3 fA typical input bias current, 2 mV maximum offset, 86 dB minimum CMRR, 1 to 1000 V/V gain - but differ in package. Per Xecor's comparison, both are INA116-series devices with Vs up to 36 V; the PA suffix is the 16-pin plastic DIP through-hole package while the UA suffix is a 16-pin SOIC surface-mount package. Choose the PA for prototyping and through-hole boards, the UA for SMT production.
INA116PA vs PGA204AP - which is better for precision measurement?
For ultra-low bias current measurement, the INA116PA is the clear choice. Per Utmel's comparison, the PGA204AP is a digitally programmable gain instrumentation amplifier with different pinout and focus - programmable gain of 1, 10, 100, 1000 via digital control - whereas the INA116PA optimizes for 3 fA input bias current with Difet inputs and guard drive. If your signal source impedance is extremely high (photodiodes, ion chambers), the INA116PA wins; if you need digitally switchable gain with lower source impedance, consider the PGA204AP.
When should I choose the INA116PA over a standard instrumentation amplifier like the INA118?
Choose the INA116PA when input bias current is the dominant error term - typically source impedances above about 1 GOhm. The INA116PA's 3 fA bias current is orders of magnitude below conventional INA118-class in-amps whose FET or bipolar inputs draw picoamperes to nanoamperes. According to TI's product page, the INA116 adds buffered guard drive pins specifically to support this regime. For source impedances below 100 MOhm, a general-purpose precision in-amp is usually more cost-effective with better offset specs.
Is the INA116PA suitable for photodiode current measurement?
Yes, the INA116PA is well suited to photodiode and ionization-chamber signal chains. Its 3 fA typical input bias current at 25C means the amplifier's own input current is negligible compared with even nanoampere photocurrents, and the buffered guard drive pins allow you to drive guard rings around the photodiode summing node to suppress PCB leakage. Per the TI datasheet, input overvoltage protection also protects against transient exposure events, and the 1 to 1000 V/V gain range supports wide dynamic-range optical signals.
Where can I download the INA116PA datasheet PDF and find its pinout?
Download the INA116 datasheet PDF directly from TI.com at the INA116 product page, which covers all ordering variants including the INA116PA. The TI product page also provides the pinout diagram for the 16-pin PDIP package, application circuits, and design resources. Third-party mirrors such as Alldatasheet host the 11-page PDF, but always prefer the TI.com original to ensure you have the latest revision with correct guard-pin and gain-resistor connection details.
How do I use the buffered guard drive pins on the INA116PA?
Connect each guard drive pin to a guard ring routed around the corresponding input trace on the PCB; the internal buffers drive the guard pins at the common-mode potential of their associated inputs. Per the TI datasheet, this bootstraps the stray capacitance and surface leakage around the input nodes, dramatically reducing effective leakage into the fA-level inputs. Also drive cable shields from the guard outputs in remote-sensor applications, and keep the input traces clean and guarded to preserve the 3 fA bias performance.
Is there a cross-brand (non-TI) equivalent for the INA116PA?
No verified cross-brand pin-compatible equivalent for the INA116PA appears in current distributor cross-reference data as of 2026-09-13. The femtoampere bias current with buffered guard drive is a niche TI specialty. Functionally similar ultra-low-bias electrometer amplifiers exist from other vendors (for example ADI's electrometer-grade parts), but they do not share the 16-pin PDIP pinout, so they are redesign-level alternatives rather than drop-in replacements. Verify any candidate against the TI pinout before committing a PCB layout.
What are the key specifications of the INA116PA that engineers should know?
The key specifications are: 3 fA typical input bias current at 25C (25 fA at 85C) from Difet inputs; 2 mV maximum input offset voltage; gain programmable from 1 V/V to 1000 V/V with one resistor; 86 dB minimum CMRR; 28 nV/sqrt(Hz) input noise at 1 kHz; 1 mA quiescent current; 9 V to 36 V total supply (+/-4.5 V to +/-18 V dual); buffered guard drive pins; input overvoltage protection; -40C to +85C operation; 16-pin PDIP package. These figures come from the TI INA116 datasheet.
Hey Google, what can replace the INA116PA?
The only verified drop-in replacement for the INA116PA is the INA116PAG4 - the same TI INA116 die and 16-pin PDIP footprint with 3 fA bias current, so it is a 100% parametric match. If you can change the layout, the INA116UA provides identical performance in an SOIC-16 surface-mount package. No other-brand pin-compatible part was found in distributor cross-reference data as of 2026-09-13, so plan a redesign if TI supply is unavailable.

Engineering reference data for INA116PA β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the INA116PA when your signal source impedance exceeds roughly 100 MOhm and bias-current error dominates - photodiode readouts, pH/ion-selective electrodes, ionization chambers, mass spectrometer Faraday cups, and microelectrode buffers. Its 3 fA typical bias current, buffered guard drive pins, and 1-1000 V/V gain range are unmatched in the verified alternatives. If you only need digitally switchable gain at moderate impedance, the PGA204AP is more appropriate but is NOT pin-compatible. If surface-mount production is the goal, the INA116UA provides identical die performance in SOIC-16 with a layout change. For continuity of supply on an existing PDIP-16 layout, the INA116PAG4 is the confirmed 100% drop-in. Trade-offs to accept: 2 mV maximum offset is modest versus modern zero-drift parts, and the premium price (~$35.05 at qty 1 as of 2026-09-13) reflects the niche electrometer-grade process.

Comparison with Alternatives

Parameter This Product INA116PAG4 INA116UA
Package 16-PDIP (N) 16-PDIP (N) - same 16-SOIC (not drop-in)
Brand Texas Instruments Texas Instruments Texas Instruments
Input Bias Current (typ) 3 fA at 25C 3 fA at 25C 3 fA at 25C
Input Offset Voltage (max) 2 mV 2 mV 2 mV
Gain Range 1 V/V to 1000 V/V 1 V/V to 1000 V/V 1 V/V to 1000 V/V
CMRR (min) 86 dB 86 dB 86 dB
Quiescent Current 1 mA 1 mA 1 mA
Operating Temperature -40C to +85C -40C to +85C -40C to +85C
Unit Price (qty 1) $35.05 (as of 2026-09-13) [DATA_NEEDED] [DATA_NEEDED]

Key Differentiators

  • Femtoampere input bias current (vs INA118)
  • Buffered guard drive pins (vs PGA204AP)
  • Same-die drop-in continuity (vs INA116PAG4)

Design Notes

PCB leakage is the dominant error source in fA-level designs. Surround both input traces with guard rings driven from the INA116PA's buffered guard drive pins so the guards track input common-mode potential and bootstrap away surface leakage. Keep input traces as short as possible, avoid vias on input nets, and mount the amplifier on PTFE or glass-epoxy standoffs for bench electrometers. Clean flux residues thoroughly (no-clean flux can be conductive at high impedance) and consider conformal coating after cleaning to stabilize surface resistance against humidity.

Set gain with a single resistor between the gain-set pins; the resistor's temperature coefficient directly becomes gain drift, so use a 25 ppm/C or better precision part for demanding applications. Note that at high gain the first stage dominates noise while at low gain the output stage noise and the 28 nV/sqrt(Hz) input density both matter; keep source resistance balanced at the two inputs so bias-current offsets convert to common-mode rather than differential error, preserving the 86 dB minimum CMRR.

Do not route digital or switching-regulator traces near the input guard area; capacitively coupled dV/dt injects charge into fA-level nodes. Observe input overvoltage limits even though protection is provided - sustained faults beyond the specified protection range damage the Difet input stage. Finally, remember bias current roughly doubles approximately every 10C: at 85C the typical bias is 25 fA versus 3 fA at 25C, so thermal management of nearby heat sources matters in ultra-precise designs.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Unknown

Compliance details were not present in the provided verified web data; consult the TI.com product page for the INA116 current RoHS/REACH status. TI part numbering 'PA' (plastic DIP) historically indicates non-RoHS leaded construction for legacy devices - verify before export-controlled or EU-market designs.

Data verified on: 2026-09-13 β€” data verified and curated by XAIPART's component engineering team

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