NXP Semiconductors

NAFE11388B40BS - ±25V 8-Input 24-Bit Universal AFE | NXP

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±25 V (HV inputs) Vdss HVQFN-64 (9x9 mm) Package
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Price updated: 2026-09-13
Volume Pricing
Qty Unit Price Extended
1 $12.5 $12.50
10 $11.25 $112.50
100 $9.8 $980.00
500 $8.75 $4,375.00
1,000 $7.9 $7,900.00
ℹ️ All prices are in USD

NAFE11388B40BS Overview

The NXP Semiconductors NAFE11388B40BS is an industrial-grade universal ±25 V 8-input analog front-end (AFE) integrating a 24-bit delta-sigma ADC, high-voltage multiplexers, programmable gain amplifier, and low-drift voltage reference in a 64-pin HVQFN (9x9 mm) package with 125 mW typical power consumption.

An analog front-end (AFE) is the signal-conditioning stage that sits between real-world sensors or voltage/current signals and a digital processing unit. Within the measurement hierarchy, the AFE -> signal conditioning IC -> data acquisition system -> industrial control chain depends on the AFE to amplify, filter, multiplex, and digitize raw analog signals with high precision. Universal-input AFEs like the NAFE11388 replace dozens of discrete components previously needed to handle mixed voltage, current, and thermocouple inputs.

Key features include eight low-leakage high-voltage (HV) fast multiplexed inputs rated for ±25 V, a 24-bit delta-sigma ADC with selectable 16/24-bit resolution, an integrated low-offset low-drift PGA with multiple gain settings, and an internal low-drift voltage reference. The HV input pins are internally diode-protected for EMC robustness and miswiring scenarios, a major reliability advantage in industrial field environments.

Architecturally, the device combines fast HV multiplexers with a high-data-rate delta-sigma converter, allowing sequential sampling of multiple channels while maintaining precision. The low-drift reference and PGA preserve accuracy over temperature, targeting industrial-grade measurement requirements without external calibration circuitry in many designs.

Typical applications include programmable logic controllers (PLC) analog input modules, building and process automation I/O, battery test and formation equipment, and condition-monitoring systems requiring multi-channel voltage and current measurement.

When designing with the NAFE11388B40BS, provide a clean low-noise supply and follow the datasheet decoupling guidance; the delta-sigma ADC resolution is only realized with careful layout around the reference and analog inputs.

This page synthesizes distributor availability, same-family drop-in alternatives, and practical design notes not found in the manufacturer datasheet.

Drop-in alternatives for NAFE11388B40BS — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with NAFE11388B40BS (same form factor and footprint) — differing in Input Voltage Range, Package, Product Type, Grade, Power Consumption.

NXP Semiconductors
Input Voltage Range: ±25 V
Package: 64-HVQFN (9x9 mm)
Product Type: Analog Front End (AFE)
Compare with NAFE11388B40BS →
NXP Semiconductors
Input Voltage Range: ±25 V (universal input)
Package: 64-HVQFN, 9x9 mm
Product Type: Universal Input Analog Front-End (AFE)
Compare with NAFE11388B40BS →
NXP Semiconductors
Input Voltage Range: ±25 V (HV inputs, diode-protected)
Package: 64-HVQFN (9x9 mm)
Product Type: Universal input analog front-end (AFE)
Compare with NAFE11388B40BS →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

NAFE11388B40BSE

✅ Drop-In
📦 HVQFN-64 (9x9)
same silicon, alternate orderable/packaging form (tray vs reel), pin-to-pin identical

📋 Reference alternative (not in catalog)

NAFE11388S40BS

✅ Drop-In ⚠️ 参数待验证
📦 HVQFN-64 (9x9)
same-package low-power family variant; S-suffix denotes different serial interface configuration vs B-suffix

📋 Reference alternative (not in catalog)

NAFE11388S40BSE

✅ Drop-In ⚠️ 参数待验证
📦 HVQFN-64 (9x9)
S-interface variant in alternate orderable form; same ±25 V 8-input low-power architecture

📋 Reference alternative (not in catalog)

NAFE13388B40BS

✅ Drop-In
📦 HVQFN-64 (9x9)
high-speed family version: higher data rate, higher power consumption vs 125 mW low-power 11388

📋 Reference alternative (not in catalog)

NAFE11388B40BS Maximum Ratings & Electrical Characteristics

Product Type Universal 8-input analog front-end (AFE)
Input Voltage Range ±25 V (HV inputs)
Number of Input Channels 8 (multiplexed, HV fast mux)
ADC Resolution 24-bit delta-sigma (16-bit mode selectable)
ADC Type Delta-Sigma
PGA Integrated low-offset, low-drift programmable gain amplifier
Voltage Reference Integrated low-drift voltage reference
Power Consumption 125 mW
Input Protection Internal diode protection on HV input pins (EMC/miswiring)
Package HVQFN-64 (9x9 mm)
Mounting Type Surface Mount
Grade Industrial

NAFE11388B40BS hvqfn-64 (9x9 mm) Pin Configuration Guide

Pin configuration for NAFE11388B40BS (hvqfn-64 (9x9 mm) package). This analog component features input, output, and power supply pins. Refer to the manufacturer datasheet for offset null, compensation, and enable pin configurations. Ideal for signal conditioning and amplifier circuits.

hvqfn-64 (9x9 mm) package pinout diagram for NAFE11388B40BS

No detailed pinout data available for NAFE11388B40BS.

Refer to the datasheet for full pin configuration.

Typical Applications

NAFE11388B40BS is suitable for 6 applications: PLC Analog Input Modules, Battery Test and Formation Equipment, Building and Process Automation I/O, Condition Monitoring and Predictive Maintenance, Test and Measurement Instrumentation, Energy Monitoring and Smart Grid Sensors.

🏭

PLC Analog Input Modules

The NAFE11388B40BS fits programmable logic controller analog input cards because its ±25 V universal inputs and 8-channel HV multiplexer cover the standard industrial signal ranges (-10 V to +10 V, 0-20 mA with external shunt) from a single device. The 24-bit delta-sigma ADC with integrated low-drift PGA delivers the resolution PLC modules require without external amplification stages, while the internally diode-protected HV pins survive field miswiring and EMC surges that routinely destroy discrete front ends. Placed behind channel terminal conditioning, one NAFE11388B40BS replaces a mux + PGA + reference + ADC chain, cutting BOM count and factory calibration points while the 125 mW budget keeps module thermal rise low in densely packed I/O racks.

Battery Test and Formation Equipment

In battery cell testing and formation channels, the NAFE11388B40BS measures cell voltages up to ±25 V with 24-bit precision across many parallel channels, thanks to its multiplexed 8-input HV front end. The low-offset, low-drift PGA preserves measurement accuracy over long soak times and elevated ambient temperatures, which directly affects capacity-derivation accuracy. Its 125 mW consumption matters when hundreds of measurement channels share a cabinet, avoiding self-heating drift. The diode-protected inputs tolerate reverse-connection events common in production fixtures. Combined with a precision shunt and a separate current-sense path, one device forms the core of a cost-effective per-cell voltage monitor within a formation-board data-acquisition chain.

🏢

Building and Process Automation I/O

Building management and process automation systems gather dozens of mixed sensors - thermocouples, resistive bridges, 0-10 V transmitters - and the NAFE11388B40BS unifies them behind one universal ±25 V input stage. The 16/24-bit selectable delta-sigma ADC lets designers trade speed for resolution per channel group, while the integrated low-drift reference removes an external precision reference from the loop-verified BOM. Its HV mux switching speed is adequate for scanning slow physical processes at typical automation sample rates. The internally protected inputs handle technician wiring errors gracefully, a decisive advantage in field-deployed I/O modules where service access is costly and downtime must be minimized over multi-year installation lifetimes.

🔧

Condition Monitoring and Predictive Maintenance

Vibration, temperature, and process-sensor signals in industrial condition-monitoring nodes benefit from the NAFE11388B40BS combination of low noise, 24-bit resolution, and ±25 V input tolerance. The low-drift PGA and reference ensure that slow-drifting sensor baselines are captured accurately over months between calibrations, while the multiplexed inputs let one AFE serve multiple sensors, shrinking remote-node PCB area and power draw. At 125 mW, the device suits passively cooled or battery-buffered monitoring nodes. The diode-protected HV inputs add resilience in electrically noisy motor-cabinet environments, where induced surges on long sensor cables would otherwise require discrete TVS and clamp networks in front of the converter.

🖥️

Test and Measurement Instrumentation

Bench and rack instrumentation - DMM front ends, data loggers, automated test fixtures - can use the NAFE11388B40BS as a compact multichannel measurement core. Its ±25 V input rating covers common measurement ranges directly, and the 24-bit delta-sigma ADC supplies the resolution class expected in precision instruments, while the integrated low-drift reference supports long-term accuracy without frequent recalibration. The fast HV multiplexer enables channel-scanning across eight inputs with microsecond-class settling depending on configuration, and the diode-protected inputs protect the instrument when users probe live circuits. This integration shortens instrument development cycles by removing discrete analog chain design, protection, and per-unit calibration complexity.

💡

Energy Monitoring and Smart Grid Sensors

Panel-level energy meters and grid-quality sensors measure bus voltages and shunt-derived currents that the NAFE11388B40BS accommodates natively within its ±25 V HV input window, with resistor scaling for higher rails. The 24-bit delta-sigma converter provides the dynamic range needed to extract small current signals from large common-mode voltages, and the low-drift reference maintains metering accuracy across seasonal temperature swings. Multi-channel multiplexing lets one device monitor three-phase nodes plus neutral and auxiliary channels. Its 125 mW draw suits always-on metering, and the internally protected inputs add the surge tolerance metering standards expect at the front end of field-installed equipment.

What is the NAFE11388B40BS?
The NAFE11388B40BS is an industrial-grade universal ±25 V 8-input analog front-end from NXP Semiconductors. It integrates high-voltage fast multiplexers, a low-offset low-drift PGA, a 24-bit delta-sigma ADC with selectable 16/24-bit resolution, and a low-drift voltage reference in a 64-pin HVQFN (9x9 mm) package, consuming about 125 mW.
What is the input voltage range of the NAFE11388B40BS?
The NAFE11388B40BS accepts ±25 V signals on its eight high-voltage analog input pins, per the NXP NAFE11388 datasheet. The HV input pins are internally diode-protected, improving robustness against EMC events and field miswiring, which is a key reason the part is specified for industrial measurement modules rather than consumer-grade front ends.
What is the difference between NAFE11388 and NAFE13388?
Both parts belong to the same NXP universal AFE family, but the NAFE13388 family is the high-speed variant while the NAFE11388 family is optimized as the low-power variant, as reflected in their datasheet titles (Universal ±25 V 8-Input High Speed AFE vs Low Power AFE). They share the same package concept and ±25 V 8-input architecture; verify exact data-rate and package code differences in the respective NXP datasheets before substituting.
Is the NAFE11388B40BS suitable for PLC analog input modules?
Yes, the NAFE11388B40BS is designed for exactly this class of application. Its ±25 V universal inputs, multiplexed 8-channel topology, 24-bit delta-sigma conversion, and diode-protected HV pins allow a single device to replace the discrete mux, PGA, ADC, and protection networks of a traditional PLC analog input card, reducing BOM count and calibration effort.
What package does the NAFE11388B40BS come in?
The NAFE11388B40BS is housed in a 64-pin HVQFN package measuring 9x9 mm, as listed on DigiKey and the NXP product page. This exposed-pad QFN format provides good thermal and electrical performance for surface-mount assembly; consult the NXP datasheet for the land-pattern and exposed-pad soldering recommendations.
What is the power consumption of the NAFE11388B40BS?
The NAFE11388B40BS consumes approximately 125 mW, according to DigiKey product data for the NAFE11388 family. This low-power figure suits densely packed multi-channel acquisition cards where total board power and thermal budget are constrained, and it distinguishes the 11388 low-power family from the higher-speed 13388 family.
Where can I buy NAFE11388B40BS and how much does it cost?
The NAFE11388B40BS can be purchased through XAIPART and major distributors. Pricing on this page starts at about 12.50 USD at quantity 1 as of 2026-09-13, with volume breaks down to approximately 7.90 USD at 1000 units. DigiKey also lists the closely related NAFE11388B40BSE variant with same-day shipping options; always confirm current stock and pricing before ordering.
Is the NAFE11388B40BS in stock?
Availability for the NAFE11388B40BS fluctuates; the closely related NAFE11388B40BSE has been listed by DigiKey as shippable the same day. XAIPART supports this part via order-on-request, so exact stock and lead time should be confirmed at quotation time. Industrial AFE demand is strong, so designing in the family with alternate orderable variants is a common risk-mitigation practice.
What is the lead time for NAFE11388B40BS?
Lead time for the NAFE11388B40BS is not fixed in the published data and must be confirmed at order time. Distribution channels such as DigiKey stock the sibling NAFE11388B40BSE for immediate shipment, which suggests reasonable availability within the family. For production volumes, request a formal quote from XAIPART or NXP authorized distributors to obtain committed lead times.
What is the best drop-in replacement for the NAFE11388B40BS?
Within the same NXP NAFE family, the closest replacements are other NAFE11388B variants such as the NAFE11388B40BSE packaging variant, and same-package family parts like the NAFE11388S40BS or the high-speed NAFE13388B40BS. All share the HVQFN-64 footprint and the ±25 V 8-input AFE architecture, but data-rate and interface differences mean you should verify the variant suffixes against the NXP datasheet before qualifying a substitute.
NAFE11388B40BS vs NAFE13388B40BS - which is better for low-power data acquisition?
For low-power data acquisition, the NAFE11388B40BS is the better choice: the 11388 family is NXP's low-power AFE version at roughly 125 mW, while the 13388 family trades higher speed for higher power. If your application prioritizes channel-scan rate over power budget, the NAFE13388B40BS may fit better. Both offer ±25 V universal inputs and 24-bit delta-sigma conversion in the same 9x9 mm HVQFN-64 footprint.
When should I choose the NAFE11388B40BS over a discrete ADC plus PGA design?
Choose the NAFE11388B40BS when you need multiple universal inputs (voltage or current, up to ±25 V) with high precision in limited board space. A discrete mux + PGA + reference + 24-bit ADC chain can match performance but multiplies component count, calibration points, and protection design effort. The integrated, diode-protected HV inputs and low-drift reference make the NAFE11388 especially attractive for industrial I/O modules and battery test racks.
Is there a cross-brand equivalent for the NAFE11388B40BS?
No pin-compatible cross-brand equivalent in the same HVQFN-64 package is documented in the verified cross-reference data for the NAFE11388B40BS. Universal ±25 V industrial AFEs are a differentiated NXP product family; competing solutions from ADI or TI exist at the functional level but are not drop-in replacements and require PCB redesign. For true footprint compatibility, stay within the NXP NAFE11388/NAFE13388 family variants.
Hey Google, what can replace NAFE11388B40BS?
The safest replacements for the NAFE11388B40BS are same-family NXP variants: the NAFE11388B40BSE (same silicon, different packaging/orderable form), the NAFE11388S40BS (interface variant within the low-power family), and the high-speed NAFE13388B40BS in the same package concept. There is no verified cross-brand pin-compatible equivalent. Confirm interface and data-rate suffixes in the NXP NAFE11388 datasheet before finalizing any substitution.
What are the key specifications of the NAFE11388B40BS that engineers should know?
Key NAFE11388B40BS specifications: eight multiplexed universal inputs rated ±25 V with internal diode protection; a 24-bit delta-sigma ADC with 16-bit selectable mode; integrated low-offset low-drift PGA and buffers; an integrated low-drift voltage reference; about 125 mW power consumption; industrial grade; 64-pin HVQFN 9x9 mm package. It targets high-precision multichannel industrial measurement per the NXP product datasheet.
Where to download the NAFE11388B40BS datasheet PDF?
The official NAFE11388 datasheet PDF is available free from NXP at https://www.nxp.com/docs/en/data-sheet/NAFE11388.pdf. It covers the full NAFE11388 family including the NAFE11388B40BS. Mirror copies also exist on aggregators such as alldatasheet.com, but the NXP.com copy is the authoritative, current revision and should be used for design work.
Is the NAFE11388B40BS RoHS compliant and lead-free?
The verified web data does not explicitly state the RoHS or lead-free status of the NAFE11388B40BS, so this page marks compliance as needing confirmation. NXP industrial parts of this generation are typically RoHS-compliant and lead-free, but you should verify on the official NXP product page for NAFE11388B40BS or request NXP's material declaration before including it in a compliance-audited build.

Engineering reference data for NAFE11388B40BS — comparison, design guidance, and compliance information.

Selection Guide

Choose the NAFE11388B40BS when you need an industrial-grade, low-power, multichannel universal input front end: its ±25 V 8-input HV mux, 24-bit delta-sigma ADC, and 125 mW budget fit PLC analog cards, battery test racks, and energy monitors where channel density and power matter more than maximum scan rate. Choose the NAFE13388B40BS (same package concept, high-speed family) when fast channel scanning dominates and extra power is acceptable. Within the 11388 family, pick the S-suffix (NAFE11388S40BS) if your host controller requires the alternate serial interface configuration; only B-suffix and BSE orderables are pin-identical in interface behavior to this part. There is no verified cross-brand drop-in: ADI or TI multi-channel AFEs are functional rivals but require a PCB redesign. For compliance-critical builds, confirm RoHS status on the NXP product page before release.

Comparison with Alternatives

Parameter This Product NAFE11388B40BSE NAFE11388S40BS NAFE13388B40BS
Package HVQFN-64 (9x9 mm) HVQFN-64 (9x9 mm) - same HVQFN-64 (9x9 mm) - same HVQFN-64 (9x9 mm) - same
Brand NXP Semiconductors NXP Semiconductors NXP Semiconductors NXP Semiconductors
Input Voltage Range ±25 V ±25 V ±25 V ±25 V
Input Channels 8 (HV mux) 8 (HV mux) 8 (HV mux) 8 (HV mux)
ADC Resolution 24-bit (16-bit selectable) 24-bit (16-bit selectable) 24-bit (16-bit selectable) 24-bit (16-bit selectable)
Family Class Low Power AFE Low Power AFE Low Power AFE High Speed AFE
Serial Interface B-suffix interface B-suffix interface S-suffix interface (different) B-suffix interface

Key Differentiators

  • Low-power family efficiency (vs NAFE13388B40BS)
  • Integrated ±25 V diode-protected HV inputs (vs Discrete mux+PGA+ADC chain)
  • Same-footprint family coverage (vs NAFE11388S40BS)

Design Notes

Give the HVQFN-64 exposed pad a solid ground via array on the PCB land pattern to achieve the datasheet thermal and noise performance. Route the eight HV analog inputs with generous spacing and guard them against adjacent digital traces; the ±25 V rating presumes clean creepage/clearance at the connector and trace level. Place the 100 nF decoupling capacitors within 2 mm of the supply pins and one bulk capacitor (10 uF) near the device. Consult the NAFE11388 datasheet layout section for the reference decoupling network.

At approximately 125 mW the NAFE11388B40BS itself is thermally trivial, but the analog supply quality directly gates the 24-bit ADC performance: feed it from a low-noise LDO (e.g., a TLE42764-class regulator) rather than a switching rail, or add a ferrite plus capacitors between a buck converter and the AVDD pin. Estimated: at 3.3 V supply this is roughly 38 mA average current, so regulator dropout and sequencing margins are modest but should still be checked against the datasheet supply ranges.

Confirm the orderable-suffix meaning before substituting within the NAFE family: the B and S suffixes denote different interface configurations, and 11388 (low power) vs 13388 (high speed) differ in data rate and power. Mixing these on one footprint without a firmware review causes communication failures. Also remember the internal diode protection on the ±25 V HV pins is for fault robustness, not continuous overvoltage operation - design the signal chain so normal-mode inputs stay within the rated window per the NXP datasheet absolute maximum section.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Unknown

Verified web data does not explicitly state RoHS/REACH/lead-free status for NAFE11388B40BS. Verify on the official NXP product page or request an NXP material declaration before compliance-audited production. Industrial-grade (not automotive AEC-Q100) per datasheet positioning.

Data verified on: 2026-09-13 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

NXP Semiconductors NAFE11388B40BS NAFE11388 NAFE13388B40BS NAFE11388B40BSE NAFE11388S40BS analog front-end (AFE) delta-sigma ADC programmable gain amplifier (PGA) HVQFN-64 QFN package family universal ±25 V input RoHS PLC analog input module battery formation testing high-voltage multiplexer low-drift voltage reference industrial data acquisition energy monitoring EMC input protection
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