Microchip Technology

PIC16F721-E/P - 8-Bit 16MHz 7KB Flash MCU | Microchip

MPN: PIC16F721-E/P ✓ Active
2.5 V to 5.5 V Vdss 25 mA source/sink Id 20-pin PDIP, 0.300 in, 7.62 mm pitch Package 20 MHz Speed 7 KB Flash, organized as 4K x 14 bits Memory
MOQ: 1 |

PIC16F721-E/P Overview

The Microchip Technology PIC16F721-E/P is an 8-bit PIC mid-range flash microcontroller with a 16 MHz internal oscillator, 7 KB of self-read/write program Flash memory, 256 bytes of SRAM, and 18 I/O pins in a 20-pin PDIP package. It integrates I2C, SPI, AUSART, CCP capture/compare/PWM, a 12-channel 8-bit ADC, two 8-bit timers, one 16-bit timer, watchdog timer, power-on reset, and brown-out reset.

A microcontroller is a programmable integrated circuit containing a CPU core, memory, I/O ports, and embedded peripherals. The PIC16F721 belongs to the PIC mid-range product hierarchy: 8-bit RISC microcontroller to general-purpose microcontroller to embedded processing IC. Its self-read/write Flash architecture supports in-circuit programming and permits firmware updates when the design exposes the appropriate programming interface.

The PIC16F721-E/P combines a 35-instruction set with eight stack levels and a 16 MHz internal oscillator. Program memory is organized as 4K by 14 bits, while the device also provides 128 bytes of non-volatile data storage. The I2C, SPI, and AUSART peripherals support serial sensor, transceiver, and communications links, while the CCP block supports capture, compare, and PWM functions.

The 12-channel 8-bit ADC supports analog measurements, and the timer resources combine TMR0, TMR2, and a 16-bit TMR1 for timing, counting, and periodic control. Individual I/O pins provide up to 25 mA source or sink current according to the supplied device data. Watchdog, power-on reset, and brown-out reset functions support dependable operation after reset events and firmware hangs.

Typical uses include compact industrial controllers, sensor nodes, serial data concentrators, motor or valve control, and small automation products. The 20-pin PDIP package is particularly useful for prototypes, educational platforms, and through-hole industrial assemblies where inspection and hand soldering are convenient.

The primary design consideration is package matching: the -/P suffix denotes the 20-pin PDIP option, so it cannot be replaced by an SSOP, SOIC, or QFN variant without a PCB change. Confirm the complete pinout and absolute operating limits in the manufacturer datasheet before finalizing a schematic or footprint.

This page consolidates the verified distributor and manufacturer information, package-specific alternatives, comparison data, and practical selection guidance into one engineer-oriented reference for the PIC16F721-E/P.

Drop-in alternatives for PIC16F721-E/P — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC16F721-E/P (same form factor and footprint) — differing in Package, Internal Oscillator, Instruction Set, Operating Temperature, ADC.

Microchip Technology
Package: 20-pin PDIP (0.300" / 7.62 mm)
Internal Oscillator: 16 MHz, selectable
Operating Temperature: -40C to +125C (extended grade)
Microchip Technology
Package: 20-Pin PDIP (DIP-20, through-hole, 300 mil)
Instruction Set: 35 instructions, 8-level hardware stack
Operating Temperature: -40 C to +85 C (Industrial)
Microchip Technology
Package: 20-pin PDIP (through-hole)
Internal Oscillator: 16 MHz, factory calibrated
Instruction Set: 35 single-word instructions, 14-bit opcode

PIC16F721-I/P

✅ Drop-In
Microchip Technology
📦 20-pin PDIP
8-bit PIC16 mid-range RISC · 35 single-word instructions, 14-bit opcode · 16 MHz (16 MIPS) / 20 MHz · 7 KB (4K x 14 words) · 128 bytes non-volatile · 256 bytes · 8 levels · 18

Contact for price

View Datasheet →

PIC16F720-I/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 20-pin PDIP
PIC16 Mid-Range 8-bit RISC · 35 instructions, 8-level hardware stack · 3.5 KB (2K x 14) · 128 B · 128 B (HEF) · 16 MHz · 1.8 V to 5.5 V · 18

Contact for price

View Datasheet →

PIC16F720-E/P

✅ Drop-In ⚠️ Specs Unverified
Microchip Technology
📦 20-pin PDIP
PIC16 8-bit mid-range · 3.5 KB (2K x 14) Flash · 128 B · 128 B · 16 MHz · 2.5 V to 5.5 V · 18 · 25 mA per pin

Contact for price

View Datasheet →

PIC16F721-E/P Maximum Ratings & Electrical Characteristics

Product Type 8-bit PIC mid-range flash microcontroller
Manufacturer Microchip Technology
CPU Architecture PIC RISC mid-range core
Processor Width 8 bit
Maximum Stated Clock Speed 20 MHz
Internal Oscillator 16 MHz
Instruction Set 35 instructions
Stack Levels 8 levels
Program Memory 7 KB Flash, organized as 4K x 14 bits
Program Memory Features Self read/write Flash memory
SRAM 256 B
Non-Volatile Data Storage 128 B
I/O Pins 18 pins
I/O Current 25 mA source/sink
ADC 12-channel, 8-bit
Serial Interfaces I2C, SPI, AUSART
Capture/Compare/PWM CCP
8-Bit Timers 2, TMR0 and TMR2
16-Bit Timers 1, TMR1
Reset and Supervision Watchdog timer, power-on reset, brown-out reset
Programming In-circuit serial programming
Supply Voltage Range 2.5 V to 5.5 V
Operating Voltage Options 2.5 V, 3.3 V, 5 V
Package 20-pin PDIP, 0.300 in, 7.62 mm pitch
Mounting Type Through-hole
Lifecycle Status Active; in production

PIC16F721-E/P 20-pin pdip, 0.300 in, 7.62 mm pitch Pin Configuration Guide

Pin configuration for PIC16F721-E/P (20-pin pdip, 0.300 in, 7.62 mm pitch package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

20-pin pdip, 0.300 in, 7.62 mm pitch package pinout diagram for PIC16F721-E/P

No detailed pinout data available for PIC16F721-E/P.

Refer to the datasheet for full pin configuration.

Typical Applications

PIC16F721-E/P is suitable for 6 applications: Industrial Sensor Controller, Serial Data Concentrator, Small Motor and Valve Control, Protocol Bridge and Sensor Node, Battery-Powered Monitoring Device, Education and Rapid Prototyping.

🏭

Industrial Sensor Controller

PIC16F721-E/P fits a compact industrial sensor controller because its 12-channel 8-bit ADC can monitor several analog inputs while two 8-bit timers and one 16-bit timer organize sampling and control periods. The 18 available I/O pins can connect discrete sensors, status indicators, and actuator drivers without requiring a large external interface. Its 16 MHz internal oscillator simplifies the clock design. The 20-pin PDIP package also makes the controller practical for prototypes and through-hole industrial assemblies. Designers should confirm analog accuracy, channel switching requirements, and environmental limits in the datasheet.

🌐

Serial Data Concentrator

PIC16F721-E/P can serve as a serial data concentrator when an installation must combine I2C, SPI, and AUSART-connected equipment into a common control node. The 7 KB self-read/write Flash provides room for protocol conversion and configuration logic, while 256 B SRAM supports temporary packet and status buffering. Its 35-instruction PIC mid-range core and eight-level stack are sufficient for modest coordination tasks. Firmware designers should budget baud-rate timing, buffering, and error recovery because the supplied data does not quantify guaranteed interface throughput.

⚡

Small Motor and Valve Control

PIC16F721-E/P is appropriate for basic motor, valve, or relay sequencing where a microcontroller must generate timing signals and read feedback inputs. The CCP peripheral supports capture, compare, and PWM operations, and TMR0, TMR2, and TMR1 provide complementary timing resources for event scheduling. The 18 I/O pins leave room for control outputs and inputs, while the 20-pin PDIP package supports hand assembly during commissioning. For inductive loads, external drivers, flyback protection, and a suitably sized bulk capacitor remain mandatory rather than being assumed to be provided by the MCU.

🧩

Protocol Bridge and Sensor Node

PIC16F721-E/P can bridge a sensor subsystem to a higher-level controller by supporting I2C, SPI, and AUSART within one compact device. The 12-channel 8-bit ADC is useful for legacy analog sensors, while digital interfaces handle more modern peripherals. With 7 KB of Flash and 256 B SRAM, the MCU fits small protocol-conversion and preprocessing tasks rather than demanding edge-compute workloads. The internal 16 MHz oscillator removes an external crystal requirement when its timing accuracy is adequate, but clock-tolerance analysis remains necessary for long communication frames or low-cost timing references.

📱

Battery-Powered Monitoring Device

PIC16F721-E/P can serve as the control element in a low-duty-cycle monitoring device because its mid-range core combines flash program memory, watchdog supervision, power-on reset, and brown-out reset in one package. The 16 MHz internal oscillator and serial peripherals support local sensor acquisition and periodic reporting, while the watchdog helps recover from unexpected firmware states. Its 2.5 V to 5.5 V supply range accommodates several rail choices. Battery suitability still depends on measured sleep current, analog-block behavior, and brown-out settings, none of which were quantified in the supplied records.

🔧

Education and Rapid Prototyping

PIC16F721-E/P is well suited to education and rapid prototyping because it combines an accessible 8-bit architecture with 35 instructions, 18 I/O pins, and a conventional 20-pin PDIP footprint. Students can connect LEDs, switches, analog inputs, and serial modules without a fine-pitch assembly process. The 7 KB Flash, 256 B SRAM, three timers, ADC, and mixed serial interfaces provide enough capability for meaningful exercises and small control projects. The through-hole package is easy to inspect and replace, although it is larger and less production-efficient than modern surface-mount options.

What are the key specifications of PIC16F721-E/P that engineers should know?
The PIC16F721-E/P is an 8-bit flash microcontroller with a 16 MHz internal oscillator, 7 KB program Flash, 256 B SRAM, 18 I/O pins, and a 20-pin PDIP package. According to the Microchip PIC16F721 product page and distributor records, it also provides I2C, SPI, AUSART, CCP, a 12-channel 8-bit ADC, three timers, watchdog reset, power-on reset, and brown-out reset.
Where can I buy PIC16F721-E/P online?
PIC16F721-E/P can be found through the verified DigiKey, Mouser, and Octopart listings included with this product. DigiKey identifies the part as an 8-bit, 16 MHz PIC microcontroller with 7 KB Flash in a 20-pin PDIP package, while Mouser lists 256 B SRAM and 18 I/O. Current unit pricing and stock quantities were not included in the supplied records, so a quotation or live distributor check is required.
What is the price of PIC16F721-E/P?
The supplied distributor results confirm that PIC16F721-E/P is offered by DigiKey, Mouser, and multiple distributors indexed through Octopart, but they do not contain a verified numerical price. The price tiers therefore use 0.00 as a non-orderable placeholder rather than presenting a fabricated quotation. Request a current quote as of 2026-10-29 and confirm the exact package suffix before placing an order.
What is the lead time for PIC16F721-E/P?
The verified Microchip product page reports that PIC16F721 is in production, but the supplied records do not state a numeric factory or distributor lead time. Distributor availability should therefore be checked for the exact -E/P ordering code. For procurement planning, do not infer a delivery interval from the active lifecycle status; confirm the current stock and lead time directly with the selected authorized distributor as of 2026-10-29.
Is PIC16F721-E/P in stock?
PIC16F721-E/P is listed by DigiKey and Mouser, and the Microchip product page identifies the PIC16F721 family as in production. However, the supplied snippets do not include a verified quantity-on-hand value for the -E/P package. The schema therefore uses BackOrder rather than claiming InStock. Check the live distributor listing or request a stock confirmation before scheduling an assembly build.
What is the operating voltage of PIC16F721-E/P?
PIC16F721-E/P operates from 2.5 V to 5.5 V according to the supplied component specifications. The same records identify 2.5 V, 3.3 V, and 5 V operating options, which allows the device to be used in both legacy 5 V logic systems and lower-voltage designs. Confirm individual peripheral, oscillator, and I/O operating limits in the Microchip datasheet before using a rail at an endpoint of the range.
What memory and peripherals does PIC16F721-E/P provide?
PIC16F721-E/P provides 7 KB of self-read/write Flash organized as 4K x 14 bits, 256 B of SRAM, and 128 B of non-volatile data storage. According to the Microchip product information, its peripherals include I2C, SPI, AUSART, CCP, a 12-channel 8-bit ADC, two 8-bit timers, one 16-bit timer, watchdog timer, power-on reset, and brown-out reset.
What can replace PIC16F721-E/P?
The closest verified same-package replacement is the industrial-temperature PIC16F721-I/P, which retains the 20-pin PDIP format but differs in temperature-grade designation. The supplied cross-reference results do not verify a cross-brand, pin-compatible 20-pin PDIP equivalent with comparable memory, peripherals, and programming model. Consequently, engineers should treat PIC16F721-I/P as a conditional same-family option and validate its complete pinout and operating limits in the manufacturer datasheet.
Is PIC16F721-E/P the same as PIC16F721-I/P?
PIC16F721-E/P and PIC16F721-I/P are not identical ordering codes even though both are associated with the 20-pin PDIP PIC16F721 device family. The -E/P combination identifies the Extended-temperature grade in a PDIP package, while -I/P identifies the Industrial-temperature grade in the same package. The available comparison result confirms package and family similarity, but the exact temperature limits and all ordering-code details must be checked before substitution.
PIC16F721-E/P vs PIC16F721-I/P: which is better for an industrial design?
PIC16F721-I/P is the more natural candidate for an industrial design because its -I ordering code denotes the Industrial-temperature grade, whereas PIC16F721-E/P uses the Extended-temperature grade. Both are identified as 20-pin PDIP PIC16F721 variants. The decisive comparison must also include operating-temperature limits, production availability, and qualification requirements; those numeric limits were not present in the supplied verification data.
When should I choose PIC16F721-E/P over PIC16F721-I/P?
Choose PIC16F721-E/P when the system specification requires the Extended-temperature ordering grade and the product will be sourced in a 20-pin PDIP package. Choose PIC16F721-I/P when the intended environment calls for the Industrial-temperature grade. Because the supplied comparison does not include full temperature limits, cost, or qualification data, do not select between them solely from the suffix; verify those records against the Microchip datasheet and current authorized-distributor data.
Is PIC16F721-E/P suitable for a small industrial controller?
PIC16F721-E/P is suitable for many small industrial-controller designs because it combines 18 I/O pins, 7 KB Flash, timers, serial interfaces, and a 12-channel 8-bit ADC in a 20-pin PDIP package. The DIP format also simplifies prototype assembly and inspection. For production use, verify the required temperature range, isolation strategy, analog accuracy, and protection levels, because detailed environmental and timing limits were not included in the supplied records.
Where do I download the PIC16F721-E/P datasheet PDF?
The official PIC16F721 product page is the preferred source for the manufacturer datasheet and reports that PIC16F721 is in production. The supplied search results also link the PIC16F721-E/P document through Digchip, FindIC, and AllDataSheet. The manufacturer page should control design decisions; third-party copies are useful for convenience but may be older mirrors. The supplied AllDataSheet result identifies a 244-page document, but no independently verified revision number was provided.
Where can I find the PIC16F721-E/P pinout?
The PIC16F721-E/P pinout is located in the 20-pin package pinout table and package drawing of the Microchip PIC16(L)F720/721 datasheet. The verified snippets confirm a 20-pin PDIP package but do not expose the individual pin names or numbering, so this output does not reproduce an unverified pin list. Use the manufacturer datasheet and the -/P package drawing for PCB construction, and do not substitute a pinout from an SSOP or SOIC variant.
What is the best Microchip equivalent for PIC16F721-E/P?
PIC16F721-I/P is the best-supported same-manufacturer candidate in the supplied evidence because it retains the 20-pin PDIP package and belongs to the same PIC16F721 family. Its key distinction is the temperature-grade code rather than the memory or core architecture. The supplied searches did not establish a cross-brand Microchip competitor with an equivalent 20-pin PDIP footprint, so no cross-brand drop-in claim is made.
What design tools and programming interfaces support PIC16F721-E/P?
PIC16F721-E/P supports in-circuit serial programming and uses the PIC16 mid-range architecture with 35 instructions and eight stack levels. The verified data also lists I2C, SPI, AUSART, and CCP peripherals, allowing the MCU to connect to sensors, transceivers, and logic peripherals. The exact programmer models, bootloaders, programming voltages, and debug headers were not provided, so engineers should consult the PIC16F721 programming and development-tool documentation.

Engineering reference data for PIC16F721-E/P — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC16F721-E/P when the design specifically needs the Extended-grade 20-pin PDIP device and can use its verified combination of 7 KB Flash, 256 B SRAM, 18 I/O pins, a 12-channel 8-bit ADC, I2C, SPI, AUSART, CCP, and three timers. Its through-hole package is also convenient for prototypes, education, and inspection-intensive industrial assemblies. Consider PIC16F721-I/P when the Industrial-temperature grade is more appropriate while retaining the same family and package. PIC16F720-I/P and PIC16F720-E/P may share the 20-pin PDIP format, but they should be selected only after verifying Flash size, SRAM, peripheral differences, configuration-bit compatibility, and pin functions. Do not use PIC16F721-E/ML, -E/SO, or other package variants as drop-in replacements on an existing -/P PCB. For every substitution, obtain the current manufacturer datasheet and verify the exact pinout, electrical limits, and programming requirements.

Comparison with Alternatives

Parameter This Product PIC16F721-I/P PIC16F720-I/P PIC16F720-E/P
Package 20-pin PDIP 20-pin PDIP 20-pin PDIP 20-pin PDIP
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Product Type 8-bit PIC mid-range flash microcontroller 8-bit PIC mid-range flash microcontroller 8-bit PIC mid-range flash microcontroller 8-bit PIC mid-range flash microcontroller
Temperature Grade Code -E Extended -I Industrial -I Industrial -E Extended

Key Differentiators

  • Through-hole package compatibility (vs PIC16F721-E/ML)
  • Integrated analog and serial peripherals (vs PIC16F720-I/P)
  • Same-family temperature-grade alternative (vs PIC16F721-I/P)

Design Notes

Use the Microchip 20-pin PDIP package drawing rather than a generic DIP footprint. The verified product is a 20-pin PDIP with a stated 0.300 in, 7.62 mm lead pitch. Confirm row spacing, pin numbering, and drill dimensions against the current datasheet before release. The same-family SSOP and SOIC ordering codes may share the PIC16F721 name but occupy different footprints, so using a surface-mount variant requires a PCB redesign and does not constitute a drop-in substitution.

Plan decoupling at every supply pin according to the Microchip datasheet, and place the required capacitors close to the device with short ground returns. The verified supply range is 2.5 V to 5.5 V, but this does not establish safe operation for every peripheral at both endpoints. Validate brown-out thresholds, operating current, and the behavior of unused I/O pins. Because exact current figures and capacitor recommendations were not supplied, obtain them from the manufacturer datasheet rather than deriving a production design from this page alone.

Do not treat the -E/P suffix as interchangeable with -E/ML, -E/SO, or other package codes. The verified DIP option is PIC16F721-E/P, whereas PIC16F721-E/ML is a 20-pin SSOP and therefore cannot replace the target on an existing through-hole PCB. Also avoid assuming that PIC16F720 variants are firmware-compatible with PIC16F721 without checking device differences, peripheral availability, configuration bits, and the complete memory map.

Keep analog inputs away from high-current switching nodes and route them with short traces over a quiet ground reference. The integrated 12-channel 8-bit ADC makes this MCU suitable for modest analog measurement, but the supplied records do not specify acquisition time, input impedance, reference accuracy, or channel-settling requirements. Follow the datasheet's analog-layout guidance, provide a stable reference, and avoid sharing narrow return paths with relay, motor, or switching-supply currents.

Compliance Information

RoHS
Unknown
REACH
Unknown
AEC-Q100
Unknown
Lead Free
Unknown
Halogen Free
Unknown
Conflict Minerals
Unknown

The supplied records identify the device as lead-free in one package-related snippet, but they do not provide authoritative RoHS, REACH, AEC-Q100, halogen-free, or conflict-minerals declarations for the exact ordering code. No compliance claim is inferred.

Data verified on: 2026-10-29 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC16F721-E/P PIC16F721 PIC16F721-I/P PIC16F720-I/P PIC16F720-E/P PIC16 mid-range core 8-bit RISC microcontroller Flash program memory self read/write Flash SRAM non-volatile data storage I2C SPI AUSART CCP 12-channel 8-bit ADC TMR0 TMR2 TMR1 watchdog timer power-on reset brown-out reset in-circuit serial programming 20-pin PDIP SMD industrial sensor controller serial data concentrator
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