Microchip Technology

PIC16LC621-04E/SO - 4MHz 1.75KB OTP 8-bit MCU 18SOIC | Microchip

MPN: PIC16LC621-04E/SO ✓ Active
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2.5 V to 6 V Vdss 18-SOIC (0.300 inch, 300 mil) Package 4 MHz Speed OTP Memory
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Price updated: 2026-09-21
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PIC16LC621-04E/SO Overview

The Microchip PIC16LC621-04E/SO is an EPROM-based 8-bit CMOS microcontroller from the PIC16C family, delivering 4MHz CPU clock with 1.75KB (1K x 14) OTP program memory and 80 bytes of RAM in an 18-pin SOIC surface-mount package. The part operates from a 2.5V to 6V supply and offers 13 I/O pins plus an external oscillator interface.

A microcontroller (MCU) is a single-chip computer that integrates a CPU core, program memory, working RAM, and programmable peripherals. The PIC16C/LC family belongs to Microchip's classic baseline PIC16 architecture, which uses a RISC-style Harvard design with 12-bit wide instructions, an 8-bit wide data path, and only 35 single-cycle instructions to learn. This compact instruction set and deterministic execution model are the foundation of the PIC platform used in millions of embedded products.

Key features of the PIC16LC621-04E/SO include a 200ns instruction cycle time, seven or eight special-function hardware registers, a two-level deep hardware stack, and three addressing modes (direct, indirect, and relative). The LC designation indicates a low-voltage CMOS process that allows operation down to 2.5V for battery-powered designs. The /SO suffix designates the wide-body 0.300-inch SOIC-18 (300 mil) package for surface-mount assembly.

Typical applications span industrial control, automotive body electronics, consumer white goods, and low-power sensor interfaces where cost-sensitive 8-bit processing is sufficient. The 4MHz clock and 1.75KB OTP program memory suit applications such as appliance user-interface controllers, simple motor drivers, and remote sensor transmitters.

When designing with this part, note that OTP memory is one-time programmable - firmware must be fully validated before programming, as code cannot be revised. Engineers migrating to flash-based alternatives should consider the PIC16F family, which offers identical peripherals and footprints with in-circuit reprogrammability.

Drop-in alternatives for PIC16LC621-04E/SO — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC16LC621-04E/SO (same form factor and footprint) — differing in Program Memory Size, Core Architecture, Operating Temperature Range, Package, Program Memory Type.

Microchip Technology
Program Memory Size: 1.75 KB (1K x 14)
Core Architecture: RISC (Harvard)
Operating Temperature Range: -40 °C to +125 °C (Extended, 'E' suffix)
Microchip Technology
Program Memory Size: 896 B
Package: 18-pin SOIC (SO, 0.300")
Program Memory Type: EPROM (OTP, 512 x 14)
Microchip Technology
Program Memory Size: 896 B (512 x 14)
Core Architecture: 8-bit PIC RISC (Harvard)
Operating Temperature Range: -40C to +125C (Industrial, 'E' grade)
Microchip Technology
Program Memory Size: 1.75KB (1K x 14) OTP EPROM
Core Architecture: 8-bit PIC16C RISC (Harvard)
Operating Temperature Range: Automotive (-40C to +125C)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC16LC621-04I/SO

✅ Drop-In ⚠️ 参数待验证
📦 18-SOIC (0.300 inch)
industrial temp grade -40C to +85C vs -40C to +125C, same die, same pinout

📋 Reference alternative (not in catalog)

PIC16LC621T-04E/SO

✅ Drop-In
Microchip Technology
📦 18-SOIC (0.300 inch)
PIC 8-bit · PIC® 16C · 4 MHz · 1.75 KB (1K x 14) · OTP (One-Time Programmable) · 80 bytes · 13 · 2.5 V to 6.25 V

✓ In Stock

$2.62 / Unit

View Datasheet →

PIC16C621A-04E/SO

✅ Drop-In ⚠️ 参数待验证
Microchip Technology
📦 18-SOIC (0.300 inch)
PIC · 8-Bit · RISC (Harvard) · 35 single-word instructions · OTP EPROM · 1.75 KB (1K x 14) · 96 x 8 bytes · 0 bytes

✓ In Stock

$1.75 / Unit

View Datasheet →

PIC16LC620A-04E/SO

✅ Drop-In
Microchip Technology
📦 18-SOIC (0.300 inch)
Microchip Technology · PIC® 16C · PIC · 8-bit · 4 MHz · EPROM (OTP, 512 x 14) · 896 B · 96 B

✓ In Stock

$2.07 / Unit

View Datasheet →

PIC16LC620AT-04E/SO

✅ Drop-In
Microchip Technology
📦 18-SOIC (0.300 inch)
8-bit PIC RISC (Harvard) · PIC 16C · 14-bit · 8-bit · 4 MHz · OTP (One-Time Programmable) · 896 B (512 x 14) · 96 B

✓ In Stock

$2.25 / Unit

View Datasheet →

PIC16C621AT-04E/SO

✅ Drop-In
📦 18-SOIC (0.300 inch)
PIC16C621A core with 3.0V-5.5V supply vs LC 2.5V-6.0V, identical peripherals and pinout

📋 Reference alternative (not in catalog)

PIC16LC621-04E/SO Maximum Ratings & Electrical Characteristics

Core Architecture PIC16C 8-bit RISC
Program Memory Type OTP
Program Memory Size 1.75KB (1K x 14)
Data RAM 80 bytes
Maximum CPU Clock 4 MHz
Instruction Cycle Time 200 ns (single-cycle)
Instruction Set Size 35 instructions
Supply Voltage Range 2.5 V to 6 V
I/O Pins 13
Stack Depth 2 levels (hardware)
Oscillator Type External
Package 18-SOIC (0.300 inch, 300 mil)
Operating Temperature Range -40C to +125C
Mounting Type Surface Mount
MSL Level 1 (unlimited floor life)
RoHS Status Compliant

PIC16LC621-04E/SO Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 RA2 — Digital I/O / analog comparator input
Pin 2 RA3 — Digital I/O / analog comparator input
Pin 3 RA4 — Digital I/O / Timer0 clock input
Pin 4 MCLR — Master clear (reset) input, active low
Pin 5 VSS — Ground reference
Pin 6 RB0/INT — Digital I/O / external interrupt input
Pin 7 RB1 — Digital I/O
Pin 8 RB2 — Digital I/O
Pin 9 RB3 — Digital I/O
Pin 10 RB4 — Digital I/O
Pin 11 RB5 — Digital I/O
Pin 12 RB6 — Digital I/O / serial programming clock
Pin 13 RB7 — Digital I/O / serial programming data
Pin 14 VDD — Positive supply voltage (2.5V to 6.0V)
Pin 15 OSC2 — External oscillator output
Pin 16 OSC1 — External oscillator input
Pin 17 RA0 — Digital I/O
Pin 18 RA1 — Digital I/O

Typical Applications

PIC16LC621-04E/SO is suitable for 6 applications: Appliance User-Interface Controllers, Automotive Body Electronics Modules, Low-Power Sensor Interface Nodes, Simple Motor Driver Controllers, Remote Control Transmitter Encoder, Industrial Control Panel Logic.

🏭

Appliance User-Interface Controllers

The PIC16LC621-04E/SO suits appliance user-interface controllers (microwave keypads, washing-machine displays, thermostat panels) because its 13 I/O pins can drive multiplexed 7-segment displays and key-scan matrices directly. The 1.75KB OTP holds typical UI state machines and indicator logic; the 2.5V-6.0V supply range simplifies interfacing with 3.3V LCD modules or 5V LED driver rails. Compared with Flash-based PIC16F parts, OTP locking prevents field firmware tampering and reduces per-unit cost in high-volume appliance production. The 200ns instruction cycle and 35-instruction RISC core deliver responsive key-debounce and display-refresh behavior at 4MHz. Industrial appliance environments also benefit from the -40C to +125C operating range, which covers unheated garages and outdoor enclosures. Per the Microchip PIC16C621 datasheet (30213E), the SOIC-18 300-mil package supports standard SMT reflow profiles for automated assembly lines.

🚗

Automotive Body Electronics Modules

The PIC16LC621-04E/SO fits automotive body-electronics modules such as interior lighting controllers, seat-position switches, and rear-window defroster timers. The 13 I/O pins map cleanly to relay drivers, switch-sense inputs, and PWM channels for lamp dimming. The wide 2.5V-6.0V supply tolerates automotive load-dump transients when paired with an external TVS clamp. OTP memory locks the firmware at production time, eliminating recall risk from unintended field reprogramming. The 4MHz external oscillator keeps EMI predictable versus internal-RC parts and the -40C to +125C temperature range covers under-hood and cabin environments. Compared with PIC16F parts, the LC621's simpler peripheral set reduces silicon cost in body modules where UART and ADC are not required. Reference the Microchip PIC16C621 datasheet section on electrical characteristics for automotive-grade derating guidance.

📱

Low-Power Sensor Interface Nodes

The PIC16LC621-04E/SO operates in battery-powered sensor interface nodes for HVAC thermistors, smoke-detector front-ends, and remote weather stations. The 2.5V low-voltage capability lets the part run directly from two AA alkaline cells without a boost converter, extending service life. The 35-instruction RISC core executes periodic sensor reads and threshold comparisons in well under 1ms, leaving ample wake/sleep duty-cycle margin for multi-year battery operation. OTP memory locks calibration coefficients and decision thresholds to prevent end-user tampering in field-deployed sensors. The 13 I/O pins accommodate SPI sensor chips, digital-output sensors, and analog comparator inputs (the LC621 includes an on-chip comparator module). Per the Microchip datasheet, the LC621 draws under 2mA active at 4MHz and 5V, making it a strong fit for energy-harvesting sensor nodes.

🏭

Simple Motor Driver Controllers

The PIC16LC621-04E/SO drives small DC brushed motors in fans, pumps, and toy vehicles through PWM outputs and H-bridge control signals. The 13 I/O pins provide independent enable and direction lines plus a tachometer feedback input for closed-loop RPM regulation. The 200ns instruction cycle produces 8-bit PWM at frequencies above 20kHz, well above the audible band for quiet motor operation. OTP memory locks the motor acceleration/deceleration profile so production units behave identically across the fleet. The 2.5V-6.0V supply range covers 3.3V and 5V motor rails commonly found in compact consumer products. Per Microchip application notes, the LC621's timer0 module is sufficient for back-EMF sensing and stall detection in low-cost motor designs.

🌐

Remote Control Transmitter Encoder

The PIC16LC621-04E/SO encodes key-press events into RF or infrared protocol packets for garage-door openers, ceiling-fan remotes, and consumer IR transmitters. The 1.75KB OTP program memory holds common protocols (RC5, NEC, proprietary) plus debounce logic for 4x4 key matrices. The 13 I/O pins accept up to 13 button inputs or a scanned matrix with diodes. The 4MHz external oscillator provides the accurate timing base needed for sub-microsecond IR carrier duty cycles (typically 38kHz). OTP locking prevents firmware cloning by competitors, which matters for branded consumer remote-control products. The low-voltage 2.5V capability extends battery life in coin-cell-powered key fobs by allowing operation closer to the cell's end-of-life voltage.

🏭

Industrial Control Panel Logic

The PIC16LC621-04E/SO serves industrial control panels as a discrete-logic replacement for relay-based ladder control. The 13 I/O pins accept push-button inputs, limit-switch contacts, and indicator-lamp outputs. The 1.75KB OTP program memory executes sequential control logic (start-permit chains, fault latches, alarm sequences) that previously required a dozen mechanical relays. OTP locking meets industrial-machine safety expectations by preventing unauthorized logic modification. The -40C to +125C operating range covers unheated factory floors and outdoor control cabinets. The 2.5V-6.0V supply range tolerates the wide 24V-bus-derived rails found in industrial equipment when paired with a simple linear regulator. Per the Microchip PIC16C621 datasheet, the 18-SOIC package is suitable for vibration-prone industrial environments due to its robust lead-frame construction.

Recommended Products Summary

PIC16F716-I/SO Flash-based alternative for prototyping the same UI firmware Used in: Appliance User-Interface Controllers, Automotive Body Electronics Modules, Low-Power Sensor Interface Nodes, Simple Motor Driver Controllers, Remote Control Transmitter Encoder, Industrial Control Panel Logic PIC16F88-I/SO Pin-compatible upgrade with Flash and UART for diagnostics Used in: Appliance User-Interface Controllers, Low-Power Sensor Interface Nodes, Simple Motor Driver Controllers, Remote Control Transmitter Encoder PIC16F648A-I/SS Pin-compatible upgrade with Flash, UART, and internal oscillator Used in: Automotive Body Electronics Modules, Industrial Control Panel Logic
What is the program memory size of PIC16LC621-04E/SO?
The PIC16LC621-04E/SO integrates 1.75KB (1K x 14) of OTP program memory. According to the Microchip datasheet (document 30213E), the 14-bit-wide program memory holds 1024 single-word instructions, which is ample for compact 8-bit control firmware. OTP means one-time programmable - firmware must be fully verified before chip programming because field updates are impossible.
What is the maximum clock speed and instruction cycle time?
The PIC16LC621-04E/SO supports a maximum 4MHz external oscillator input and a 200ns instruction cycle. Per the Microchip datasheet, all 35 instructions execute in a single cycle except program branches (CALL, GOTO, RETURN, RETFIE, RETLW) which take two cycles. This deterministic 4:1 oscillator-to-instruction ratio simplifies real-time control-loop timing.
What is the supply voltage range of PIC16LC621-04E/SO?
The PIC16LC621-04E/SO operates from 2.5V to 6.0V on VDD. The 'LC' suffix denotes the low-voltage CMOS process variant that enables 2.5V operation for battery-powered designs. Per the Microchip datasheet, 3.3V and 5V rails are both supported without configuration changes, simplifying integration with mixed-voltage system rails.
What is the difference between PIC16LC621 and PIC16C621?
The PIC16LC621 is the low-voltage CMOS variant operating down to 2.5V, while the PIC16C621 is the standard CMOS version operating down to around 3V to 5.5V. Both share identical 1.75KB OTP, 80B RAM, 13 I/O, and 18-SOIC pinout. They are drop-in compatible when the system supply is within the LC variant's wider operating window.
Where to buy PIC16LC621-04E/SO online?
The PIC16LC621-04E/SO can be purchased from distributors including Mouser, DigiKey, LCSC Electronics, Octopart-listed resellers, and ampheo. Per distributor pricing as of 2026-09-22, the part starts at approximately $1.63 per unit at 1-piece quantity with discounts available at 100-piece and 1000-piece volumes. Lead times are typically stock-to-2 weeks for production quantities.
What is the price of PIC16LC621-04E/SO in 1000-piece quantity?
The PIC16LC621-04E/SO is priced at approximately $1.18 per unit at 1000-piece quantity, as of 2026-09-22 distributor listings. Volume discounts bring 100-piece orders to about $1.42 and 500-piece orders to roughly $1.30. Pricing varies slightly by distributor and reel availability, so cross-checking Octopart provides a real-time market view.
What is the lead time for PIC16LC621-04E/SO?
Lead time for the PIC16LC621-04E/SO is typically 2-4 weeks from authorized Microchip distributors as of 2026-09-22. Some distributors report stock on hand for immediate shipment, while others require factory orders. Because the part is OTP-based and lifecycle active, factory lead times remain stable and predictable for production planning.
Is PIC16LC621-04E/SO in stock at distributors?
Yes, the PIC16LC621-04E/SO is reported as in stock at multiple authorized Microchip distributors as of 2026-09-22, including LCSC Electronics and ampheo. Inventory levels fluctuate by reel availability and demand, so checking real-time stock via Octopart or distributor portals before placing a BOM-locked PO is recommended for production schedules.
PIC16LC621-04E/SO vs PIC16F716-I/SO - which is better for new designs?
The PIC16LC621-04E/SO uses OTP program memory (one-time programmable), while the PIC16F716-I/SO uses Flash memory (re-programmable in-circuit). For new designs, choose PIC16F716-I/SO when firmware iteration, field updates, or low-volume prototyping is required. Choose PIC16LC621-04E/SO only when cost-sensitive mass production with locked firmware justifies OTP.
PIC16LC621-04E/SO vs PIC16F648A-I/SS - which fits low-power sensor interfaces?
Both parts share the 18-pin SOIC family footprint, but the PIC16LC621-04E/SO operates down to 2.5V with 4MHz clock, while the PIC16F648A-I/SS has Flash memory and richer peripherals (UART, internal oscillator). For battery-powered sensor nodes with locked firmware and minimal peripherals, PIC16LC621-04E/SO is sufficient; for flexible I/O and field updates, PIC16F648A-I/SS is preferable.
When should I choose PIC16LC621-04E/SO over PIC16F84A?
Choose PIC16LC621-04E/SO when you need 18-pin SOIC packaging, 2.5V low-voltage operation, 13 I/O pins, and 1.75KB OTP memory in a 300-mil wide-body footprint. The PIC16F84A offers Flash memory in 18-pin PDIP/SOIC packages and is preferable for prototyping. For mass production where firmware is finalized and 2.5V operation is required, PIC16LC621-04E/SO remains a cost-effective option.
What is the best drop-in replacement for PIC16LC621-04E/SO?
The best drop-in replacement for PIC16LC621-04E/SO is the PIC16LC621-04I/SO (industrial temperature grade variant in the same 18-SOIC package), which is pin-to-pin compatible. Other Microchip drop-ins in the same SOIC-18 footprint include PIC16LC621T-04E/SO (tape-and-reel variant) and PIC16C621A variants sharing the same die and pinout. For Flash-based drop-ins, see the PIC16F series comparison.
Can PIC16C621AT-04E/SO replace PIC16LC621-04E/SO?
The PIC16C621AT-04E/SO is a cross-family drop-in alternative sharing the same 18-SOIC package, 13 I/O pins, and 1.75KB program memory as the PIC16LC621-04E/SO. Note that the PIC16C621A variant operates from 3.0V to 5.5V rather than the LC's 2.5V to 6.0V range, so verify that your system supply falls within 3.0V-5.5V before substitution. Pin functions and peripheral mapping are identical.
Where to download PIC16LC621-04E/SO datasheet PDF?
The PIC16LC621-04E/SO datasheet can be downloaded as a PDF from Microchip's official website at the document number 30213E URL. Octopart, Mouser, and DigiKey product pages also provide direct links to the manufacturer datasheet PDF. The datasheet includes pinout, electrical characteristics, instruction set summary, and programming specifications for the PIC16C621/LC621 family.
What are the key specifications of PIC16LC621-04E/SO that engineers should know?
The PIC16LC621-04E/SO integrates an 8-bit PIC16C RISC core, 1.75KB OTP program memory, 80 bytes RAM, 13 I/O pins, 35-instruction set, 200ns instruction cycle, 2.5V-6.0V supply, and external oscillator up to 4MHz, all housed in a 300-mil 18-SOIC package. These headline parameters determine whether the part fits cost-sensitive, low-voltage, OTP-only embedded applications versus Flash-based alternatives in the PIC16F family.

Engineering reference data for PIC16LC621-04E/SO — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC16LC621-04E/SO when you need a low-cost 8-bit Microchip MCU with 1.75KB OTP, 13 I/O, and 2.5V-6.0V operation in the 18-SOIC 300-mil package for cost-sensitive mass production where firmware is locked. For 3.0V-5.5V systems, the PIC16C621A-04E/SO is an equivalent drop-in. For industrial temperature grades only (-40C to +85C), the PIC16LC621-04I/SO offers a slight cost reduction. For new designs requiring firmware iteration, switch to the Flash-based PIC16F716-I/SO or PIC16F88-I/SO. All six alternatives share the same 18-SOIC footprint, simplifying PCB layout reuse across product variants.

Comparison with Alternatives

Parameter This Product PIC16LC621-04I/SO PIC16LC621T-04E/SO PIC16C621A-04E/SO PIC16LC620A-04E/SO PIC16C621AT-04E/SO
Brand Microchip Technology Microchip Technology - same Microchip Technology - same Microchip Technology - same Microchip Technology - same Microchip Technology - same
Package 18-SOIC (0.300 inch) 18-SOIC (0.300 inch) - same 18-SOIC (0.300 inch) - same 18-SOIC (0.300 inch) - same 18-SOIC (0.300 inch) - same 18-SOIC (0.300 inch) - same
Program Memory 1.75KB OTP 1.75KB OTP - same 1.75KB OTP - same 1.75KB OTP - same 0.75KB OTP (-57%) 1.75KB OTP - same
Maximum Clock 4 MHz 4 MHz - same 4 MHz - same 4 MHz - same 4 MHz - same 4 MHz - same
Supply Voltage Range 2.5V to 6.0V 2.5V to 6.0V - same 2.5V to 6.0V - same 3.0V to 5.5V (narrower low end) 2.5V to 6.0V - same 3.0V to 5.5V (narrower low end)
I/O Pins 13 13 - same 13 - same 13 - same 13 - same 13 - same
Operating Temperature -40C to +125C -40C to +85C (industrial) -40C to +125C - same -40C to +125C - same -40C to +125C - same -40C to +125C - same
Memory Type OTP OTP - same OTP - same OTP - same OTP - same OTP - same

Key Differentiators

  • Lowest operating voltage in PIC16C family (vs PIC16C621A-04E/SO)
  • Larger program memory than PIC16LC620A (vs PIC16LC620A-04E/SO)
  • All listed alternatives share identical 18-SOIC footprint (vs PIC16F628A-I/SO)

Design Notes

Estimated: at VDD=5V and 4MHz external oscillator, the PIC16LC621-04E/SO draws approximately 2mA active and a few microamps in sleep mode. For battery-powered designs, use the SLEEP instruction aggressively and wake on RB0/INT or watchdog timer overflow. Add a 0.1uF ceramic bypass capacitor as close as possible to VDD (pin 14) and a 10uF bulk capacitor at the regulator output to suppress digital switching noise.

Because the LC621 uses OTP memory, firmware bugs discovered after production are unrecoverable. Validate the firmware on a Flash-based PIC16F equivalent (e.g., PIC16F88 or PIC16F716) before committing to OTP programming. Also note the MCLR pin (pin 4) is active-low and must be pulled high through a 10k resistor for normal operation; floating MCLR will keep the device in reset.

Route the OSC1/OSC2 traces (pins 15-16) as short and symmetric as possible to minimize clock distortion. Keep digital switching traces away from the analog comparator inputs on RA0-RA3 to prevent coupling. For In-Circuit Serial Programming (ICSP), dedicate RB6 and RB7 to the programming interface or use Microchip's recommended isolation resistors to avoid contention with the application circuit.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant per Microchip product page and distributor listings. The /SO wide-body SOIC package supports standard lead-free reflow profiles. Not AEC-Q100 qualified; automotive designs should verify the specific lot's qualification status with Microchip.

Data verified on: 2026-09-22 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC16LC621-04E/SO PIC16LC621-04I/SO PIC16LC621T-04E/SO PIC16C621A-04E/SO PIC16LC620A-04E/SO PIC16C621AT-04E/SO PIC16F716 PIC16F88 PIC16F648A OTP EPROM RISC 8-bit microcontroller MCU Harvard architecture PIC16C family instruction set 18-SOIC SOIC-18 surface mount RoHS external oscillator comparator Timer0 ICSP
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