PIC18F65K22-E/MR - 64KB Flash, 64MHz 8-bit MCU, 64-VQFN | Microchip
MPN: PIC18F65K22-E/MR ✓ Active| Qty | Unit Price | Extended |
|---|---|---|
| 1 | $5.6 | $5.60 |
| 10 | $5.04 | $50.40 |
| 100 | $4.48 | $448.00 |
| 500 | $3.95 | $1,975.00 |
| 1,000 | $3.5 | $3,500.00 |
PIC18F65K22-E/MR Overview
Key features include a 64 MHz internal oscillator (16 MIPS instruction throughput), up to 54 digital I/O pins, three 12-bit A/D converters with up to 16 input channels, two comparators, four 16-bit timers, two CCP modules, three EUSART and two SPI/I2C peripherals, plus a CTMU peripheral. The integrated USB 2.0 full-speed transceiver supports USB device/host/OTG operation without an external PHY, simplifying BOM cost. The on-chip 12-bit ADC delivers conversion rates up to 100 ksps, suitable for sensor signal acquisition and closed-loop control.
The PIC18F65K22 uses an enhanced Harvard RISC core with hardware multiply and a C-optimized instruction set, making it suitable for both assembly and C development under MPLAB X IDE and XC8/MCC code generation. Peripherals connect via a peripheral pin select (PPS) multiplexer that allows flexible pin assignment, easing PCB layout under tight package constraints. The device also includes an LCD driver capable of driving up to 288 segments, making it a fit for user-interface appliances and instrumentation.
Typical applications include battery-powered IoT sensor nodes with capacitive touch user input, USB peripherals such as HID or CDC class devices, industrial control panels combining analog sensing with segment-LCD readouts, and portable medical instrumentation where low quiescent current directly extends battery life. The wide operating voltage range allows direct connection to 2xAA or Li-Ion battery stacks.
When designing with this part, pay attention to the VQFN exposed pad layout - the thermal pad must be soldered to a sufficiently large copper pour to meet thermal and electrical ground connectivity requirements. Decoupling should follow the datasheet recommended pattern with at least one 0.1uF and one 1uF/10uF bulk capacitor placed close to the VDD pins, and the USB bus must use the datasheet-specified 90-ohm differential pair routing. The device is provided in tape-and-reel packaging suitable for SMT assembly lines.
This page synthesizes distributor pricing, pin-compatible alternatives within the PIC18 K-series family, and practical design notes beyond what the manufacturer datasheet alone provides - including comparison against the -I temperature grade sibling and a checklist of common pitfalls when migrating between MR and PT 64/80-pin packages.
Drop-in alternatives for PIC18F65K22-E/MR — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.
Variants in this series
Same-series models that are drop-in compatible with PIC18F65K22-E/MR (same form factor and footprint) — differing in Package, Maximum Clock Speed, ADC, Program Memory (Flash), Core Architecture.
Quick Comparison Tool — Select alternative parts for side-by-side comparison:
PIC18F65K22-I/MR
✅ Drop-In📋 Reference alternative (not in catalog)
PIC18F65K22T-E/MR
✅ Drop-In📋 Reference alternative (not in catalog)
PIC18F66K22-E/MR
✅ Drop-In✓ In Stock
$3.79 / Unit
View Datasheet →PIC18F65K90-E/MR
✅ Drop-In ⚠️ Specs Unverified✓ In Stock
$4.6 / Unit
View Datasheet →PIC18F65K40-E/MR
✅ Drop-In ⚠️ Specs Unverified✓ In Stock
$2.32 / Unit
View Datasheet →PIC18F65K22-E/PT
✅ Drop-In✓ In Stock
$4.39 / Unit
View Datasheet →PIC18F65K22-E/MR Maximum Ratings & Electrical Characteristics
| Family | PIC18F K-series (PIC18F6XK22) |
| Core | 8-bit PIC enhanced RISC |
| Program Memory | 64 KB Flash |
| RAM | 4 KB |
| EEPROM | 1 KB |
| Maximum Clock Speed | 64 MHz (16 MIPS) |
| Supply Voltage Range | 1.8 V to 5.5 V |
| Operating Temperature Range | -40C to +125C (Extended) |
| I/O Pins | 54 |
| Package | 64-pin VQFN (9x9 mm, exposed pad) |
| ADC | 12-bit, up to 16 channels |
| USB | USB 2.0 Full-Speed OTG (integrated transceiver) |
| Timers | 4 x 16-bit, 2 x 8-bit |
| Communication Peripherals | 2x EUSART, 2x SPI/I2C, 2x MSSP |
| Special Features | nanoWatt XLP, CTMU, LCD driver (up to 288 segments), PPS |
| RoHS Status | Compliant |
PIC18F65K22-E/MR Pin Configuration
| Pin 1 | RB0/INT0/FLT0 — PORTB bit 0 / external interrupt 0 / PWM fault input |
| Pin 2 | RB1/INT1 — PORTB bit 1 / external interrupt 1 |
| Pin 3 | RB2/INT2 — PORTB bit 2 / external interrupt 2 |
| Pin 4 | RB3/INT3 — PORTB bit 3 / external interrupt 3 |
| Pin 5 | RB4/KBI0 — PORTB bit 4 / KBI interrupt 0 |
| Pin 6 | RB5/KBI1 — PORTB bit 5 / KBI interrupt 1 |
| Pin 7 | RB6/KBI2/PGC — PORTB bit 6 / KBI interrupt 2 / ICSP clock |
| Pin 8 | RB7/KBI3/PGD — PORTB bit 7 / KBI interrupt 3 / ICSP data |
| Pin 9 | VSS — Ground reference |
| Pin 10 | VDD — Positive supply voltage |
| Pin 11 | RC0/SOSCO — PORTC bit 0 / secondary oscillator output |
| Pin 12 | RC1/SOSCI — PORTC bit 1 / secondary oscillator input |
| Pin 13 | RC2/T1G — PORTC bit 2 / Timer1 gate |
| Pin 14 | RC3 — PORTC bit 3 |
| Pin 15 | RC4 — PORTC bit 4 |
| Pin 16 | RC5 — PORTC bit 5 |
| Pin 17 | RC6 — PORTC bit 6 |
| Pin 18 | RC7 — PORTC bit 7 |
| Pin 19 | VSS — Ground reference |
| Pin 20 | VDD — Positive supply voltage |
| Pin 21 | RD0/PSP0 — PORTD bit 0 / parallel slave port bit 0 |
| Pin 22 | RD1/PSP1 — PORTD bit 1 / parallel slave port bit 1 |
| Pin 23 | RD2/PSP2 — PORTD bit 2 / parallel slave port bit 2 |
| Pin 24 | RD3/PSP3 — PORTD bit 3 / parallel slave port bit 3 |
| Pin 25 | RD4/PSP4 — PORTD bit 4 / parallel slave port bit 4 |
| Pin 26 | RD5/PSP5 — PORTD bit 5 / parallel slave port bit 5 |
| Pin 27 | RD6/PSP6 — PORTD bit 6 / parallel slave port bit 6 |
| Pin 28 | RD7/PSP7 — PORTD bit 7 / parallel slave port bit 7 |
| Pin 29 | VSS — Ground reference |
| Pin 30 | VDD — Positive supply voltage |
| Pin 31 | RE0/RD — PORTE bit 0 / parallel slave port read control |
| Pin 32 | RE1/WR — PORTE bit 1 / parallel slave port write control |
| Pin 33 | RE2/CS — PORTE bit 2 / parallel slave port chip select |
| Pin 34 | RE3 — PORTE bit 3 (input only) |
| Pin 35 | RE4 — PORTE bit 4 |
| Pin 36 | RE5 — PORTE bit 5 |
| Pin 37 | RE6 — PORTE bit 6 |
| Pin 38 | RE7 — PORTE bit 7 |
| Pin 39 | RF0 — PORTF bit 0 |
| Pin 40 | RF1/AN6 — PORTF bit 1 / analog input 6 |
| Pin 41 | RF2/AN7 — PORTF bit 2 / analog input 7 |
| Pin 42 | RF3/AN8 — PORTF bit 3 / analog input 8 |
| Pin 43 | RF4/AN9 — PORTF bit 4 / analog input 9 |
| Pin 44 | RF5/AN10/CVREF — PORTF bit 5 / analog input 10 / CV reference |
| Pin 45 | RF6/AN11 — PORTF bit 6 / analog input 11 |
| Pin 46 | RF7 — PORTF bit 7 |
| Pin 47 | RG0 — PORTG bit 0 |
| Pin 48 | RG1 — PORTG bit 1 |
| Pin 49 | RG2 — PORTG bit 2 |
| Pin 50 | RG3 — PORTG bit 3 |
| Pin 51 | RG4 — PORTG bit 4 |
| Pin 52 | MCLR/RE3 — Master clear reset input |
| Pin 53 | RA0/AN0 — PORTA bit 0 / analog input 0 |
| Pin 54 | RA1/AN1 — PORTA bit 1 / analog input 1 |
| Pin 55 | RA2/AN2 — PORTA bit 2 / analog input 2 |
| Pin 56 | RA3/AN3 — PORTA bit 3 / analog input 3 |
| Pin 57 | RA4/T0CKI — PORTA bit 4 / Timer0 clock input |
| Pin 58 | RA5/AN4 — PORTA bit 5 / analog input 4 |
| Pin 59 | RA6/OSC2 — PORTA bit 6 / oscillator output |
| Pin 60 | RA7/OSC1 — PORTA bit 7 / oscillator input |
| Pin 61 | VSS — Ground reference |
| Pin 62 | VDD — Positive supply voltage |
| Pin 63 | D+/RG6 — USB D+ / PORTG bit 6 |
| Pin 64 | D-/RG7 — USB D- / PORTG bit 7 |
Typical Applications
PIC18F65K22-E/MR is suitable for 7 applications: Battery-Powered IoT Sensor Nodes with Capacitive Touch, USB HID/CDC Peripherals, Industrial Control Panels with Segment LCD, Portable Medical Instrumentation, Home Appliance User Interfaces, Automotive Body Electronics (Non-Safety), Educational / Maker Development Platforms.
Battery-Powered IoT Sensor Nodes with Capacitive Touch
The PIC18F65K22-E/MR is well suited for battery-powered IoT sensor nodes with capacitive touch user input because the integrated CTMU peripheral simplifies touch button and slider implementation without external timing components. The nanoWatt XLP technology achieves deep-sleep currents in the nanoampere range, extending battery life to years on 2xAA cells. The 12-bit ADC provides accurate sensor measurement while the wide 1.8-5.5V supply range allows direct connection to alkaline or Li-Ion battery stacks. Designers can use sleep mode + periodic CTMU scanning to keep average current under 1 uA.
Recommended
USB HID/CDC Peripherals
The PIC18F65K22-E/MR is ideal for USB HID or CDC class peripherals because the integrated USB 2.0 full-speed transceiver supports device, host, and OTG operation without an external PHY, reducing BOM cost. The 64 KB Flash accommodates USB stacks, class drivers, and application code, while 4 KB SRAM handles USB buffering plus application data. The on-chip USB voltage regulator powers the transceiver directly from the 5V VBUS rail. Per Microchip datasheet section, the USB peripheral requires a 48 MHz clock source, achievable via the PLL from a 16 MHz crystal or internal oscillator.
Recommended
Industrial Control Panels with Segment LCD
The PIC18F65K22-E/MR fits industrial control panels combining analog sensing with segment-LCD readouts because the integrated LCD driver supports up to 288 segments without an external LCD controller. The 12-bit ADC with up to 16 channels handles multi-sensor acquisition, while the extended -40C to +125C temperature grade tolerates factory-floor environments. PPS allows flexible routing of digital signals around the LCD glass connector, easing PCB layout. The 64 KB Flash accommodates HMI state machines, calibration tables, and segment mapping arrays.
Recommended
Portable Medical Instrumentation
The PIC18F65K22-E/MR serves portable medical instrumentation well because nanoWatt XLP technology minimizes quiescent current, directly extending battery life in compliance-critical applications. The 12-bit ADC with up to 16 channels captures physiological sensor signals such as temperature, pulse, or impedance measurements with adequate resolution for clinical-grade accuracy. The USB OTG transceiver supports tethered data transfer to host PCs for record-keeping. Extended temperature grade and Watchdog Timer with separate oscillator enhance system reliability for unattended operation.
Recommended
Home Appliance User Interfaces
The PIC18F65K22-E/MR is suitable for home appliance user interfaces combining capacitive touch with segment LCD display because the CTMU peripheral simplifies touch button implementation and the integrated LCD driver eliminates external display controllers. The wide 1.8-5.5V supply accepts unregulated wall-adapter outputs, reducing power supply cost. PWM outputs drive LED indicators or backlight brightness control. The extended -40C to +125C temperature grade tolerates kitchen or laundry environments where ambient temperature can spike during operation.
Recommended
Automotive Body Electronics (Non-Safety)
The PIC18F65K22-E/MR handles automotive body electronics such as seat controllers, mirror modules, or ambient lighting drivers because the extended -40C to +125C temperature grade meets under-hood or cabin thermal stress. The 12-bit ADC reads sensor inputs such as position or temperature, and PWM channels drive LED dimming or motor speed control. Note that for safety-critical applications, designers should select an AEC-Q100-qualified MCU; the PIC18F65K22 family is suitable for non-safety body modules and comfort systems. USB OTG supports diagnostics interface to service tools.
Recommended
Educational / Maker Development Platforms
The PIC18F65K22-E/MR fits educational and maker development platforms because the 64-pin VQFN exposes nearly the full PIC18 peripheral set including USB, ADC, CTMU, and LCD driver, enabling hands-on exploration of multiple peripheral classes in one part. MPLAB X IDE and the MPLAB Code Configurator (MCC) provide graphical peripheral setup, lowering the entry barrier for students and hobbyists. The extensive Microchip application note library and active community forum accelerate learning. The tape-and-reel -E/MR variant is typically available through distributors in sample quantities.
Recommended
Recommended Products Summary
Engineering reference data for PIC18F65K22-E/MR — comparison, design guidance, and compliance information.
Selection Guide
Comparison with Alternatives
| Parameter | This Product | PIC18F65K22-I/MR | PIC18F65K22T-E/MR | PIC18F66K22-E/MR | PIC18F65K90-E/MR | PIC18F65K40-E/MR |
|---|---|---|---|---|---|---|
| Package | 64-VQFN (9x9) | 64-VQFN (9x9) - same | 64-VQFN (9x9) - same | 64-VQFN (9x9) - same | 64-VQFN (9x9) - same | 64-VQFN (9x9) - same |
| Brand | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology | Microchip Technology |
| Program Flash | 64 KB | 64 KB | 64 KB | 128 KB | 32 KB | 32 KB |
| RAM | 4 KB | 4 KB | 4 KB | 4 KB | 2 KB | 2 KB |
| Maximum Clock | 64 MHz | 64 MHz | 64 MHz | 64 MHz | 64 MHz | 64 MHz |
| Operating Temperature | -40C to +125C (E) | -40C to +85C (I) | -40C to +125C (E) | -40C to +125C (E) | -40C to +125C (E) | -40C to +125C (E) |
| USB 2.0 FS | Yes (OTG) | Yes (OTG) | Yes (OTG) | Yes (OTG) | Yes (OTG) | Yes (OTG) |
| CTMU | Yes | Yes | Yes | Yes | Yes | No (CWG/DSM instead) |
Key Differentiators
- Integrated USB 2.0 FS OTG with on-chip transceiver (vs PIC18F46K22-I/P (40-pin DIP, no USB))
- nanoWatt XLP deep-sleep current in nanoampere range (vs PIC18F4550-I/P (legacy USB PIC))
- Integrated CTMU peripheral for capacitive touch (vs Discrete touch ICs (e.g., MTCH6102))
Design Notes
The 64-pin VQFN (MR) package exposes a central thermal pad that must be soldered to a sufficiently large copper pour for electrical ground and thermal dissipation. Per Microchip layout guidelines, the thermal pad via pattern should use an array of 0.3 mm thermal vias on a 1 mm pitch connecting to an internal ground plane. Insufficient thermal pad soldering can result in 10-15C junction temperature rise under typical loads and may violate reliability specifications at the +125C extended temperature operating point.
Decoupling must follow the datasheet recommendation: place one 0.1 uF ceramic capacitor as close as possible to each VDD/VSS pair, plus a bulk 1 uF or 10 uF tantalum/ceramic at the package entry point. The USB transceiver's internal voltage regulator requires an additional 1 uF + 100 nF pair on the VUSB pin. For battery-powered designs using nanoWatt XLP sleep modes, place the decoupling network so that bulk capacitors do not leak through MCU pins during deep-sleep current measurements.
When migrating between the /MR (64-VQFN) and /PT (64-TQFP) packages, verify the footprint, thermal pad, and PCB layout match before declaring drop-in compatibility. The two packages have identical pin functions but different PCB land patterns and thermal pad requirements - the VQFN requires central pad soldering while the TQFP has no thermal pad. Additionally, USB design requires the D+/D- pair to be routed as a 90-ohm differential pair on the top layer over a continuous ground plane; routing over splits or with vias in the pair degrades USB signal integrity.
Compliance Information
RoHS and REACH compliance per Microchip product environmental certification. Not AEC-Q100 qualified - for safety-critical automotive designs, use AEC-Q100-qualified PIC18F variants or PIC32MX MCUs.
