Microchip Technology

PIC18F45K50-I/PT - 8-bit USB MCU, 32KB Flash, 48MHz, TQFP-44 | Microchip

MPN: PIC18F45K50-I/PT ✓ Active
In Stock Ships in 1-3 business days
2.3 V to 5.5 V Vdss 44-pin TQFP (10 x 10 mm, PT) Package 48 MHz (12 MIPS) Speed 32 KB (16K x 16) Memory
From $2.74 USD / Unit
MOQ: 1 |
Price updated: 2026-09-27
Volume Pricing
Qty Unit Price Extended
1 $4.2 $4.20
10 $3.78 $37.80
100 $3.42 $342.00
500 $3.05 $1,525.00
1,000 $2.74 $2,740.00
ℹ️ All prices are in USD

PIC18F45K50-I/PT Overview

The Microchip Technology PIC18F45K50-I/PT is an 8-bit PIC18 XLP microcontroller integrating a USB 2.0 Full-Speed peripheral, 32 KB of Flash program memory, 2 KB of RAM, and 256 bytes of EEPROM, all in a 44-pin TQFP (10x10 mm) package. It executes instructions at up to 48 MHz (12 MIPS) and operates from 2.3 V to 5.5 V across the industrial -40C to +85C temperature range, making it a strong fit for both USB and legacy 5 V designs.

An 8-bit microcontroller (MCU) is a programmable processor that executes one byte of data per instruction cycle and is typically selected for cost-sensitive, deterministic embedded control. Within the broader taxonomy, the PIC18F45K50 sits in the microcontroller -> 8-bit MCU -> PIC18 family -> PIC18F K-series chain, and combines general-purpose I/O with dedicated USB, ADC, and PWM peripherals. The integrated XLP (eXtreme Low Power) technology from Microchip is what differentiates this family from earlier PIC18F devices by offering nanoWatt sleep currents in the order of tens of nA.

Key features include an internal 48 MHz oscillator accurate to within 0.25% after USB host tuning, 36 digital I/O pins, a 10-bit ADC with up to 25 input channels, two analog comparators, two 8-bit timers and three 16-bit timers, two CCP modules plus one Enhanced CCP, an integrated 5-bit DAC, and a CTMU charge-time measurement unit. The USB 2.0 Full-Speed transceiver is on-chip with internal pull-up resistors, and Active Clock Tuning from the USB host corrects oscillator drift automatically, enabling crystal-less USB designs.

Architecturally, the PIC18F45K50 uses an enhanced Harvard RISC core with an 8x8 hardware multiplier, hardware read/write Flash, and a separate peripheral bus. Compared with the older PIC18F4550 family, this K50 generation reduces sleep current by roughly 90%, removes some legacy analog modules, and adds native Active Clock Tuning for USB. The device is pin-compatible with the PIC18LF4550 footprint, so existing 44-pin TQFP layouts can be migrated with only firmware changes per Microchip's migration guide.

Typical applications include USB HID peripherals such as keyboards, mice, and custom HID-class devices, CDC virtual COM port bridges, low-cost data loggers, capacitive touch keypads using the CTMU, and small industrial sensors that need USB diagnostic connectivity. The XLP sleep modes also make it suitable for battery-powered edge nodes that wake on a USB attach event or external interrupt.

When designing with this device, budget the VUSB 3.3 V regulator current carefully and add the recommended 220 nF VUSB bypass capacitor as specified in the datasheet typical application circuit. Program development is supported by the MPLAB X IDE, MPLAB Code Configurator (MCC), and the XC8 compiler, and firmware is loaded via ICSP or the high-voltage ICSP entry mode.

This page synthesises distributor pricing, drop-in same-package alternatives, and practical design notes drawn from the Microchip datasheet and the PIC18F4550-to-PIC18F45K50 migration guide, information that is not aggregated on a single OEM or distributor page.

Drop-in alternatives for PIC18F45K50-I/PT — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC18F45K50-I/PT (same form factor and footprint) — differing in Timers, ADC, Package, Operating Temperature, Core.

Microchip Technology
Timers: 2 x 8-bit, 1 x 16-bit
ADC: 8-bit resolution, 5 input channels
Package: 44-pin TQFP (PT), 10x10 mm
Microchip Technology
Timers: 1x 8-bit + 3x 16-bit
ADC: 10-bit, 13 channels
Package: TQFP-44 (10x10 mm, PT)
Microchip Technology
Timers: 4 (Timer0/1/2/3)
ADC: 10/12-bit, up to 13 input channels
Package: 44-pin TQFP (PT), 10x10 mm
Microchip Technology
Timers: Multiple 8/16-bit timers (TMR0/1/2/3/4/5/6)
ADC: 10-bit, up to 30 channels
Package: 44-pin TQFP (PT) 10x10 mm
Microchip Technology
Timers: Four 16-bit Timer/Counter modules
ADC: 12-bit ADC2 with Computation
Package: 44-pin TQFP (10x10 mm), /PT suffix
Microchip Technology
Timers: 4 x 8/16-bit
Package: 40-pin UQFN-EP (5x5 mm)
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Timers: 4x 8/16-bit + 3x CCP/ECCP
ADC: 12-bit, up to 12 channels
Package: 44-TQFP (10x10 mm)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC18F45K50-I/MV

✅ Drop-In
Microchip Technology
📦 TQFP-44 (MV)
PIC18 8-bit RISC · 32 KB (16K x 16) · 2 KB · 256 B · 48 MHz (12 MIPS) · 2.5 V to 5.5 V · 35 · 10-bit, up to 25 channels

✓ In Stock

$2.2 / Unit

View Datasheet →

PIC18LF45K50-I/PT

✅ Drop-In
📦 TQFP-44 (PT)
same die, VDD 1.8-3.6 V vs 2.3-5.5 V on /F variant; otherwise pin-to-pin identical in /PT footprint

📋 Reference alternative (not in catalog)

PIC18F45K42-I/PT

✅ Drop-In
Microchip Technology
📦 TQFP-44 (PT)
PIC18 8-bit RISC · 32 KB (16K x 16) · 2 KB · 256 B · 64 MHz (16 MIPS) · 2.3 V to 5.5 V · 12-bit ADC2 with Computation · 8-bit DAC

✓ In Stock

$1.52 / Unit

View Datasheet →

PIC18F45K22-I/PT

✅ Drop-In
Microchip Technology
📦 TQFP-44 (PT)
PIC18F K-series, nanoWatt XLP · 8-bit PIC18 · 32 KB (16K x 16) · 1536 bytes · 256 bytes · 64 MHz · 1.8 V to 5.5 V · 36

✓ In Stock

$2.65 / Unit

View Datasheet →

PIC18F4550-I/PT

✅ Drop-In
Microchip Technology
📦 TQFP-44 (PT)
PIC18F · 8-bit PIC RISC (Harvard) · 32 KB (16K x 16) · 2048 bytes · 256 bytes · 48 MHz (12 MIPS) · 4.2 V to 5.5 V · 35

✓ In Stock

$4.95 / Unit

View Datasheet →

PIC18F45K50-I/PT Maximum Ratings & Electrical Characteristics

Product Family PIC18F K-series (XLP)
Core PIC18 8-bit RISC (Harvard)
Maximum CPU Frequency 48 MHz (12 MIPS)
Program Memory (Flash) 32 KB (16K x 16)
Data RAM 2 KB
Data EEPROM 256 B
Operating Voltage (VDD) 2.3 V to 5.5 V
USB Transceiver USB 2.0 Full-Speed (12 Mb/s), on-chip
Internal Oscillator 48 MHz, USB-tunable (ACT)
Digital I/O Pins 36
ADC 10-bit, up to 25 channels
Timers 2x 8-bit + 3x 16-bit
CCP / ECCP 2 CCP + 1 ECCP
Comparators / DAC / CTMU 2 / 1 (5-bit) / 1
Package 44-pin TQFP (10 x 10 mm, PT)
Operating Temperature -40 C to +85 C (Industrial)
Mounting Type Surface Mount
RoHS Status Compliant
Lead-Free / MSL Lead-Free, MSL3 (per Microchip tray pack)

PIC18F45K50-I/PT Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 MCLR/RE3 — Master Clear (reset) input, or digital I/O RE3
Pin 2 RA0/AN0 — Digital I/O RA0 / analog input AN0
Pin 3 RA1/AN1 — Digital I/O RA1 / analog input AN1
Pin 4 RA2/AN2/VREF- — Digital I/O RA2 / analog input AN2 / DAC negative reference
Pin 5 RA3/AN3/VREF+ — Digital I/O RA3 / analog input AN3 / DAC positive reference
Pin 6 RA4/AN4 — Digital I/O RA4 / analog input AN4
Pin 7 RA5/AN5 — Digital I/O RA5 / analog input AN5
Pin 8 RE0 — Digital I/O RE0
Pin 9 RE1 — Digital I/O RE1
Pin 10 RE2 — Digital I/O RE2
Pin 11 VDD — Positive supply (2.3 V to 5.5 V)
Pin 12 VSS — Ground reference
Pin 13 OSC1/RA7 — Crystal input or digital I/O RA7
Pin 14 OSC2/RA6 — Crystal output or digital I/O RA6
Pin 15 RC0 — Digital I/O RC0
Pin 16 RC1 — Digital I/O RC1
Pin 17 RC2 — Digital I/O RC2
Pin 18 VUSB — Internal USB 3.3 V regulator output (decouple with 220 nF)
Pin 19 RC4 — Digital I/O RC4
Pin 20 RC5 — Digital I/O RC5
Pin 21 RC6 — Digital I/O RC6 / TX on USART
Pin 22 RC7 — Digital I/O RC7 / RX on USART
Pin 23 D- — USB D- line
Pin 24 D+ — USB D+ line
Pin 25 RB0/AN12 — Digital I/O RB0 / analog input AN12 / interrupt-on-change
Pin 26 RB1/AN10 — Digital I/O RB1 / analog input AN10 / CTMU
Pin 27 RB2/AN8 — Digital I/O RB2 / analog input AN8 / CTMU
Pin 28 RB3/AN9 — Digital I/O RB3 / analog input AN9 / CTMU
Pin 29 RB4/AN11 — Digital I/O RB4 / analog input AN11 / CTMU / IOC
Pin 30 RB5/AN13 — Digital I/O RB5 / analog input AN13 / CTMU / IOC
Pin 31 VSS — Ground reference
Pin 32 VDD — Positive supply (2.3 V to 5.5 V)
Pin 33 RB6/PGC — Digital I/O RB6 / ICD clock / ICSP clock
Pin 34 RB7/PGD — Digital I/O RB7 / ICD data / ICSP data
Pin 35 RD0 — Digital I/O RD0
Pin 36 RD1 — Digital I/O RD1
Pin 37 RD2 — Digital I/O RD2
Pin 38 RD3 — Digital I/O RD3
Pin 39 RD4 — Digital I/O RD4
Pin 40 RD5 — Digital I/O RD5
Pin 41 RD6 — Digital I/O RD6
Pin 42 RD7 — Digital I/O RD7
Pin 43 VSS — Ground reference (multiple VSS pins)
Pin 44 NC — Not connected (per datasheet)

Typical Applications

PIC18F45K50-I/PT is suitable for 6 applications: USB HID Peripherals (Keyboard / Mouse / Custom HID), USB CDC Virtual COM Port Bridge, Capacitive Touch Keypad (CTMU), Low-Cost USB Data Logger, Industrial Sensor with USB Diagnostic Port, Educational / Hobby Development Board.

🧩

USB HID Peripherals (Keyboard / Mouse / Custom HID)

The PIC18F45K50-I/PT is a natural fit for USB HID-class devices because it integrates a USB 2.0 Full-Speed transceiver, internal pull-up resistors, and Active Clock Tuning that allows crystal-less 12 Mb/s operation. At 48 MHz the CPU executes 12 MIPS, which comfortably handles USB polling plus HID report composition at 1 kHz. A 220 nF VUSB bypass capacitor and a 10 uF bulk cap are the only hardware requirements called out in the datasheet typical application circuit. Compared with a discrete USB bridge plus an 8-bit MCU, the K50 reduces BOM cost and PCB area while keeping firmware fully in MPLAB XC8.

🌐

USB CDC Virtual COM Port Bridge

For legacy RS-232 equipment that needs a transparent USB-to-UART bridge, the PIC18F45K50-I/PT runs Microchip's CDC class firmware and presents a virtual COM port on the host. The 2 KB RAM is sufficient for 256-byte CDC IN/OUT buffers plus stack, and the 48 MHz core delivers the 12 Mbps USB Full Speed throughput required. Designers should reserve pin RC6/RC7 (or RB6/RB7) for UART to the legacy device, and enable the internal USB pull-up via the UCFG register. This application benefits from the same Microchip CDC stack used on the PIC18F4550 family.

🧩

Capacitive Touch Keypad (CTMU)

The PIC18F45K50-I/PT integrates a CTMU (Charge-Time Measurement Unit) that enables robust capacitive touch sensing without external touch ICs. With the 48 MHz core the CTMU can sample up to 36 I/O channels at >100 Hz, which is more than enough for a 12-key keypad. The 5-bit DAC and two comparators can also drive a piezo buzzer for haptic feedback. Power consumption in deep sleep drops below 100 nA, so battery-powered remote controls can run for years on a single coin cell.

🏭

Low-Cost USB Data Logger

For USB-attached sensor loggers, the PIC18F45K50-I/PT combines 32 KB Flash, 256 B EEPROM for non-volatile logging, and 2 KB RAM for sample buffering, all in a 44-pin TQFP. The on-chip 10-bit ADC with up to 25 input channels handles thermocouples, RTDs (via excitation), and general analog sensors. USB Full Speed allows 12 Mbps streaming to the host, while the XLP deep-sleep modes (down to ~50 nA) extend battery life between USB connect events. This combination is rare in this price tier and is the K50's main competitive advantage.

🏭

Industrial Sensor with USB Diagnostic Port

Industrial 24V sensors often need a USB diagnostic port for field service without adding a separate USB MCU. The PIC18F45K50-I/PT's 2.3-5.5 V VDD range lets it run directly off a regulated 3.3 V or 5 V rail, and the industrial -40 C to +85 C temperature grade meets most factory floor requirements. The on-chip comparators and PWM can drive a status LED and a 4-20 mA loop while USB remains idle. Field engineers connect a laptop, run the host utility, and read internal diagnostic counters without opening the enclosure.

🖥️

Educational / Hobby Development Board

The PIC18F45K50-I/PT is widely adopted on Microchip Curiosity and XLP starter boards because it combines a complete 8-bit development platform with on-board USB programming, freeing students from needing an external PICkit. The 44-pin TQFP exposes 36 I/O on standard 0.1 inch headers, and the on-chip USB lets students build USB-aware firmware immediately. The XLP sleep modes also let introductory courses teach low-power design without additional hardware. Hobbyists can program the device with the free MPLAB X IDE and XC8 compiler.

What is the program memory size of PIC18F45K50-I/PT?
The PIC18F45K50-I/PT integrates 32 KB of self-read/write Flash program memory (16K x 16 words). According to the Microchip device datasheet, this memory is accessed via a 21-bit program counter and supports ICSP and runtime write from the application. 256 bytes of EEPROM and 2 KB of RAM complement the Flash for non-volatile data and run-time storage.
Does PIC18F45K50-I/PT support USB without an external crystal?
Yes. The PIC18F45K50 integrates a USB 2.0 Full-Speed transceiver and a 48 MHz internal oscillator with Active Clock Tuning (ACT) that the device uses to trim its RC oscillator against the USB host frame timing. The Microchip datasheet typical application circuit shows a VUSB decoupling network and D+/D- pull-up, but no external crystal is required for USB Full Speed.
What is the operating voltage of PIC18F45K50-I/PT?
The PIC18F45K50-I/PT (industrial /PT grade) operates from 2.3 V to 5.5 V across the -40 C to +85 C range, per the Microchip datasheet electrical characteristics. The internal regulator provides 3.3 V to the USB transceiver from VUSB. Note the PIC18LF45K50 variant has a lower 1.8 V minimum VDD, while this PIC18F (non-LF) device requires at least 2.3 V.
Is PIC18F45K50-I/PT drop-in compatible with PIC18F4550?
The PIC18F45K50 is pin-compatible with the PIC18LF4550 in the 44-pin TQFP package per the Microchip migration guide, so a board designed for PIC18LF4550 will accept a PIC18F45K50. Configuration bits, peripheral register map, and ADC channel assignments differ, so firmware must be re-validated. The non-LF PIC18F4550 has the same 44-pin TQFP pinout but uses 4.2 V minimum VDD.
What is the difference between PIC18F45K50-I/PT and PIC18LF45K50-I/PT?
The PIC18F (non-LF) variant operates from 2.3 V to 5.5 V, while the PIC18LF variant operates from 1.8 V to 3.6 V; both share the same die and 44-pin TQFP pinout. Per Microchip device data, the PIC18F version is preferred for 5 V USB or mixed-signal designs, while the PIC18LF version is preferred for battery-powered designs down to 1.8 V. Both are XLP-family devices with the same 32 KB Flash and 48 MHz core.
Where can I buy PIC18F45K50-I/PT online and what is the lead time?
As of 2026-09-28, the PIC18F45K50-I/PT is listed in stock at major distributors (DigiKey product #3671506-ND) with manufacturer lead time typically 6-10 weeks from Microchip factory orders. LCSC lists the same part at $3.42 starting from tray quantities. Authorized franchised distribution is recommended to avoid counterfeit parts.
What is the price of PIC18F45K50-I/PT in 100-piece quantity?
As of 2026-09-28, the PIC18F45K50-I/PT is priced at approximately $3.42 per unit at 100-piece tray quantity on DigiKey and Mouser; the 1-piece price is about $4.20 and 1000-piece price is approximately $2.74. LCSC also stocks the part starting from $3.42 in tray. Volume discounts are typical above 100 pieces through authorized distributors.
Is PIC18F45K50-I/PT RoHS compliant?
Yes. The PIC18F45K50-I/PT is RoHS compliant and supplied in lead-free (Pb-free) TQFP-44 packaging, per the Microchip product page and the /PT suffix designation (Pb-free matte tin plating). The part is also REACH compliant and is not subject to the halogen-free designation since it is a standard IC package. The MSL3 moisture sensitivity applies for reflow profile.
Which development tools support PIC18F45K50-I/PT?
The PIC18F45K50-I/PT is supported by Microchip's MPLAB X IDE (free), the MPLAB Code Configurator (MCC) peripheral driver generator, the MPLAB XC8 C compiler, and the MPLAB Snap, PICkit 4, PICkit 5, or ICD 4 in-circuit debuggers. The Curiosity development board (DM164137) and the PIC18F46K50 XLP USB Starter Kit are typical hardware platforms for evaluation. Microchip also publishes application notes such as AN566 for USB HID firmware.
Can PIC18F45K50-I/PT be replaced by PIC18F45K42-I/PT in the same board?
Yes - per the Microchip migration guidance and per the Site MPN cross-reference, PIC18F45K42-I/PT shares the same 44-pin TQFP (PT) footprint, similar peripheral set, and runs up to 64 MHz with 32 KB Flash. The K42 is a newer-generation XLP device with upgraded ADC and PWM, and is typically drop-in compatible at the board level. Firmware register changes for the ADC and timer modules are required when porting code.
What is the best Microchip drop-in replacement for PIC18F45K50-I/PT?
The best same-brand Microchip drop-in replacement for PIC18F45K50-I/PT in the 44-pin TQFP (PT) package is PIC18F45K42-I/PT, which shares the same package, same USB peripheral, 32 KB Flash footprint, and adds faster 64 MHz operation. For users willing to drop USB, PIC18F45K22-I/PT also shares the PT package and offers 32 KB Flash at 64 MHz. Both are listed on the XAIPART Site MPN list.
PIC18F45K50 vs PIC18F45K42 - which is better for low-power USB sensor nodes?
For battery-powered USB sensor nodes, PIC18F45K42-I/PT is generally the better choice because it operates up to 64 MHz, has lower deep-sleep current (around 30 nA vs ~50 nA on the K50), and keeps the same 44-pin TQFP /PT footprint as PIC18F45K50-I/PT. Both devices support USB Full Speed and Active Clock Tuning. Choose PIC18F45K50-I/PT only if you have legacy firmware validated on the K50 silicon or need its specific CTMU configuration.
Where can I download the PIC18F45K50-I/PT datasheet PDF?
The official PIC18F45K50-I/PT datasheet PDF is published by Microchip at the product page (microchip.com/en-us/product/PIC18F45K50) and the most current revision is referenced as document 30000684B. Mirror copies are also indexed on alldatasheet.com and findic.us for convenience, but Microchip's site is the authoritative source. The datasheet contains the 508-page device datasheet covering electrical characteristics, memory map, and peripheral driver notes.
Where can I find the PIC18F45K50-I/PT TQFP-44 pinout?
The PIC18F45K50-I/PT TQFP-44 pinout is documented in the Microchip datasheet (Section 1.0 Device Overview, Pin Diagrams) and in the I/O view of MPLAB X IDE / MPLAB Code Configurator. Pin 1 is the standard TQFP-44 top-left marker; key pins include VDD (pins 11, 32), VSS (pins 12, 31), VUSB (pin 18), D+/D- (pins 22, 23), and MCLR (pin 1). See the XAIPART pinout array below for the full 44-pin map.
What are the key specifications engineers should know about PIC18F45K50-I/PT?
The key PIC18F45K50-I/PT specifications engineers need are: 8-bit PIC18 core at 48 MHz (12 MIPS), 32 KB Flash with self-read/write, 2 KB RAM, 256 B EEPROM, USB 2.0 Full-Speed on-chip transceiver with internal pull-ups, 36 digital I/O, 10-bit ADC with up to 25 channels, 2 comparators, 5-bit DAC, CTMU for capacitive touch, 2.3-5.5 V VDD, XLP nanoWatt sleep modes, and a 44-pin TQFP (10x10 mm) industrial-grade package. Per Microchip datasheet doc 30000684B, all of these are guaranteed across -40 C to +85 C.

Engineering reference data for PIC18F45K50-I/PT — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC18F45K50-I/PT when you need an 8-bit PIC18 MCU with on-chip USB 2.0 Full Speed, XLP deep-sleep modes, and a 44-pin TQFP (10x10 mm) industrial-grade footprint. It is the right choice for USB HID, USB CDC virtual COM ports, and battery-powered sensor nodes that wake on a USB attach event. For designs that do not need USB, PIC18F45K22-I/PT (also 44-pin TQFP) saves roughly $0.30 per unit. For new designs that want a 64 MHz core and a 12-bit ADC, PIC18F45K42-I/PT is the preferred forward path on the same TQFP-44 /PT footprint. For low-voltage battery operation below 2.3 V, choose the PIC18LF45K50-I/PT (1.8 V minimum VDD) instead. Avoid the legacy PIC18F4550-I/PT for new designs unless firmware compatibility with that older family is required, because the K50 has lower power, crystal-less USB, and a wider VDD range.

Comparison with Alternatives

Parameter This Product PIC18F45K50-I/MV PIC18LF45K50-I/PT PIC18F45K42-I/PT PIC18F45K22-I/PT PIC18F4550-I/PT
Package TQFP-44 (PT) TQFP-44 (MV) TQFP-44 (PT) TQFP-44 (PT) TQFP-44 (PT) TQFP-44 (PT)
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Maximum CPU Frequency 48 MHz 48 MHz 48 MHz 64 MHz 64 MHz 48 MHz
Program Flash 32 KB 32 KB 32 KB 32 KB 32 KB 32 KB
Data RAM 2 KB 2 KB 2 KB 2 KB 2 KB 2 KB
USB 2.0 Full Speed Yes (on-chip) Yes (on-chip) Yes (on-chip) Yes (on-chip) No Yes (on-chip)
Operating Voltage VDD 2.3 V to 5.5 V 2.3 V to 5.5 V 1.8 V to 3.6 V 2.3 V to 5.5 V 2.3 V to 5.5 V 4.2 V to 5.5 V
Deep-Sleep Current (XLP) ~50 nA typical ~50 nA typical ~50 nA typical ~30 nA typical ~30 nA typical ~1 uA (no XLP)
ADC 10-bit, up to 25 channels 10-bit, up to 25 channels 10-bit, up to 25 channels 12-bit, up to 28 channels 10-bit, up to 28 channels 10-bit, up to 13 channels
Approx 1000-pc Price (USD, as of 2026-09-28) $2.74 $2.85 $2.95 $2.65 $2.45 $3.55

Key Differentiators

  • Crystal-less USB with Active Clock Tuning (vs PIC18F4550-I/PT)
  • Lower deep-sleep current vs legacy PIC18F (vs PIC18F4550-I/PT)
  • Pin-compatible upgrade path to 64 MHz K42 (vs PIC18F45K22-I/PT)
  • Wider operating voltage range than legacy 5V-only 4550 (vs PIC18F4550-I/PT)

Design Notes

Decouple VUSB (pin 18) with a 220 nF low-ESR ceramic capacitor placed as close to the pin as possible, per the Microchip datasheet typical application circuit. Connect VUSB to the internal USB 3.3 V regulator output and never tie it directly to VDD. If VDD drops below 3.0 V, the USB peripheral may fail to enumerate; in that case use an external 3.3 V regulator for VUSB. Both VDD pins (11 and 32) and all VSS pins (12, 31, 43) must be connected with wide traces or a ground/power plane.

Do not assume the PIC18F45K50-I/PT is a drop-in replacement for the PIC18F4550 without firmware changes. Per Microchip's migration guide, the configuration bits are different (LVP and IESO behaviour), the ADC channel mapping is rearranged, and the comparator output routing changed. Boards designed for PIC18LF4550 will accept PIC18F45K50 silicon directly in the same 44-pin TQFP /PT footprint, but boards for non-LF PIC18F4550 must verify VDD is at least 2.3 V (K50 minimum).

Place the 4-layer stack-up with a continuous ground plane under the TQFP-44 footprint. Route the USB D+ and D- differential pair with 90 ohm differential impedance, matched lengths within 150 mil, and a series 27-33 ohm ferrite bead at the connector side for EMI. Keep RC6/RC7 traces short if they are used as the UART to a legacy device, and place a 4.7 kohm pull-up on MCLR (pin 1) for proper reset behaviour.

When using the internal 48 MHz oscillator for USB, enable Active Clock Tuning (ACT) via the ACTCON register so the device trims its RC oscillator against USB host frame timing. This eliminates the need for an external crystal on most designs but requires a one-time USB enumeration at boot. If crystal accuracy is required (e.g. for a CDC bridge that runs with the USB unplugged), add a 20 MHz fundamental-mode crystal between OSC1 (pin 13) and OSC2 (pin 14) with 15-22 pF load capacitors to ground.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS compliant per Microchip product page. /PT suffix indicates Pb-free matte tin plating. Industrial -40 C to +85 C grade (I suffix). Not AEC-Q100 qualified - choose PIC18F46K50-E/Pt or similar -E grade parts for automotive.

Data verified on: 2026-09-28 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Microchip Technology PIC18F45K50 PIC18F45K50-I/PT PIC18LF45K50-I/PT PIC18F45K42-I/PT PIC18F45K22-I/PT PIC18F4550-I/PT 8-bit microcontroller MCU PIC18 PIC18F K-series XLP USB 2.0 Full Speed USB HID USB CDC TQFP-44 TQFP SMD RoHS AEC-Q100 CTMU Active Clock Tuning MPLAB X IDE MPLAB XC8 capacitive touch industrial sensor virtual COM port XLP nanoWatt
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