Microchip Technology

PIC32MX350F256HT-I/MR - 80MHz 32-bit MCU 256KB Flash | Microchip

MPN: PIC32MX350F256HT-I/MR ✓ Active
In Stock Ships in 1-3 business days
2.5 V / 3.3 V Vdss 64-pin VQFN (9x9 mm) with EP Package 80 MHz (100 MHz on -100I grade) Speed 256 KB (256K x 8) Memory
From $3.55 USD / Unit
MOQ: 1 |
Price updated: 2026-10-02
Volume Pricing
Qty Unit Price Extended
1 $6.16 $6.16
10 $5.78 $57.80
100 $5.05 $505.00
500 $4.45 $2,225.00
1,000 $3.92 $3,920.00
3,300 $3.55 $11,715.00
ℹ️ All prices are in USD

PIC32MX350F256HT-I/MR Overview

The Microchip PIC32MX350F256HT-I/MR is a 32-bit MIPS M4K microcontroller running up to 80 MHz (100 MHz for the -100I speed grade) with 256 KB of Flash program memory and 64 KB of SRAM, housed in a 64-pin VQFN (9x9 mm) package with exposed pad (EP). It operates from a 2.5V/3.3V supply and integrates a rich set of peripherals including two SPI/I2S, two I2C, USB 2.0 (Device/Host/OTG), five UART, five 16-bit timers, a 10-bit 1 Msps ADC with up to 28 channels, and a Parallel Master Port. According to Microchip product page, the PIC32MX3/4 family is engineered for the perfect combination of 32-bit performance, memory density, and integrated peripherals at a low cost.

A 32-bit microcontroller (MCU) is a single-chip computer integrating a high-performance CPU core, Flash program memory, RAM, and peripheral blocks such as ADC, timers, and communication controllers. Within the embedded hierarchy, PIC32MX belongs to: microcontroller -> 32-bit MCU -> MIPS-based MCU -> RISC MCU -> CMOS integrated circuit. The MIPS32 M4K core provides hardware multiply/divide and a 5-stage pipeline, enabling 1.56 DMIPS/MHz efficiency which makes PIC32MX MCUs suitable for signal processing, USB, and graphics user-interface tasks that 8/16-bit MCUs cannot sustain.

Key features of the PIC32MX350F256HT-I/MR include: 80 MHz core (up to 100 MHz on -100I speed grade), 256 KB Flash with live-update capability, 64 KB SRAM, 28 ADC channels at 10-bit 1 Msps, USB 2.0 Full-Speed OTG, 5 timers/counters, 5 UART, 2 SPI/I2S, 2 I2C, PMP (Parallel Master Port) for graphics or external memory, and a CTMU (Charge Time Measurement Unit) for touch and capacitive sensing. Industrial-grade -40C to +85C operation supports harsh-environment deployment.

The internal 8 MHz FRC oscillator with PLL provides flexible system clocking and minimizes external crystal count. Hardware DMA, PMP bus mastering, and dedicated peripheral bus reduce CPU load in USB-audio, USB-HID, or TFT-display designs. A separate 16 KB device Flash page is dedicated to the USB bootloader for field-upgradeable firmware without an external programmer.

Typical applications include industrial control HMIs with TFT panels, USB peripherals (CDC, HID, mass storage, audio), IoT edge nodes, sensor fusion, motor control, and consumer audio. The wide peripheral mix supports both connectivity (USB, UART) and analog front-end integration in a single chip.

When designing with this MCU, allocate 16 KB of Flash for the USB bootloader if field-upgradeability is required and reserve a complete Flash page for live-update operations. Always connect the EP (exposed pad) of the VQFN-64 to a clean ground plane with multiple thermal vias for proper heat dissipation and electrical reference.

This page synthesizes distributor pricing, drop-in alternatives, and practical design notes drawn from the PIC32MX3xx family datasheet and Microchip reference designs - information not consolidated on any single distributor page.

Drop-in alternatives for PIC32MX350F256HT-I/MR — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32MX350F256HT-I/MR (same form factor and footprint) — differing in ADC, Package, Operating Temperature, Timers, DMA Channels.

Microchip Technology
ADC: 10-bit, 16-channel, up to 1 Msps
Package: 64-QFN (9x9 mm)
Operating Temperature: -40 °C to +85 °C (Industrial)
Microchip Technology
ADC: 10-bit, up to 16 channels
Package: 64-pin QFN (9x9 mm)
Timers: 5 x 16-bit + 2 x 32-bit
Microchip Technology
ADC: 10-bit
Package: 64-pin VQFN (9x9 mm, MR)
Operating Temperature: -40 C to +85 C (Industrial, suffix I)
Microchip Technology
ADC: 10-bit, up to 28 channels
Package: 64-VQFN (MR) 9x9 mm
Operating Temperature: -40C to +105C (V grade)
Microchip Technology
ADC: 10-bit, up to 28 channels (per family datasheet)
Package: 64-VQFN (9x9 mm) with exposed thermal pad
Operating Temperature: -40C to +85C (industrial, I)
Microchip Technology
ADC: 10-bit, 28 channels, 1 Msps
Package: 64-VQFN (9x9 mm)
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
ADC: 10-bit, 16 channels, 1 Msps
Package: 64-pin QFN (9x9 mm), MR suffix
DMA Channels: 6
Microchip Technology
ADC: 10-bit, 1 Msps, up to 28 channels
Package: 64-QFN (9x9 mm) with exposed pad
Operating Temperature: -40C to +85C (Industrial)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32MX350F256H-I/MR

✅ Drop-In
📦 VQFN-64 (9x9)
same die, no T&R suffix; 256 KB Flash, 64 KB RAM identical; same VQFN-64 (9x9) footprint

📋 Reference alternative (not in catalog)

PIC32MX350F256H-V/MR

✅ Drop-In
📦 VQFN-64 (9x9)
automotive grade -40C to +105C instead of -40C to +85C; same Flash/RAM/peripherals; same VQFN-64 footprint

📋 Reference alternative (not in catalog)

PIC32MX350F256HT-100I/MR

✅ Drop-In
📦 VQFN-64 (9x9)
100 MHz speed grade vs 80 MHz (+25% clock); otherwise identical die/Flash/RAM/package

📋 Reference alternative (not in catalog)

PIC32MX350F256HT-120I/MR

✅ Drop-In
📦 VQFN-64 (9x9)
120 MHz speed grade vs 80 MHz (+50% clock); same VQFN-64 footprint, same Flash/RAM

📋 Reference alternative (not in catalog)

PIC32MX250F256HT-I/MR

✅ Drop-In
Microchip Technology
📦 VQFN-64 (9x9)
MIPS32 M4K · 32-bit RISC · 50 MHz / 83 DMIPS · 2.3 V to 3.6 V · 256 KB (256K x 8) · 32 KB · 64-QFN (9x9 mm) · Surface Mount

✓ In Stock

$3.35 / Unit

View Datasheet →

PIC32MX270F512HT-50I/MR

✅ Drop-In
Microchip Technology
📦 VQFN-64 (9x9)
MIPS32 M4K 32-bit RISC · 50 MHz (83 DMIPS) · 512 KB (512K x 8) · 64 KB · 64-pin QFN (9x9 mm) · -40C to +85C (industrial, 'I' suffix) · 2.3V to 3.6V · USB 2.0 Full-Speed Device/Host/OTG

✓ In Stock

$4.74 / Unit

View Datasheet →

PIC32MX340F512HT-80I/MR

✅ Drop-In
Microchip Technology
📦 VQFN-64 (9x9)
MIPS32 M4K 32-bit · 5-stage Harvard · 80 MHz (105 DMIPS) · MIPS32 / MIPS16e (up to 40% code compression) · 512 KB (256 KB user Flash + 12 KB boot Flash) · 32 KB (execute-from-RAM supported) · 2.5 V to 3.6 V · 53

✓ In Stock

$4.36 / Unit

View Datasheet →

PIC32MX450F256HT-I/MR

✅ Drop-In
Microchip Technology
📦 VQFN-64 (9x9)
MIPS32 M4K · 32-Bit Single-Core · 80 MHz · 256 KB (256K x 8) · 64 KB · 49 · 2.3 V to 3.6 V · 10-bit, 1 Msps, up to 28 channels

✓ In Stock

$4.2 / Unit

View Datasheet →

PIC32MX350F256HT-I/MR Maximum Ratings & Electrical Characteristics

Core Architecture MIPS32 M4K
Data Bus Width 32-bit
Maximum CPU Frequency 80 MHz (100 MHz on -100I grade)
Program Memory (Flash) 256 KB (256K x 8)
SRAM 64 KB
Operating Voltage 2.5 V / 3.3 V
Supply Voltage Range 2.3 V to 3.6 V
ADC 10-bit, up to 28 channels, 1 Msps
DAC None
Timers 5 x 16-bit
UART 5
SPI / I2S 2
I2C 2
USB USB 2.0 Full-Speed OTG
Parallel Master Port (PMP) Yes
CTMU (Capacitive Touch) Yes
DMA Channels Yes (hardware DMA)
Operating Temperature -40C to +85C (Industrial -I)
Package 64-pin VQFN (9x9 mm) with EP
Mounting Type Surface Mount
MSL Level 3 (168 hours)
RoHS Status Compliant

PIC32MX350F256HT-I/MR Pin Configuration

Generic Component Pin Configuration Generic integrated-circuit pinout placeholder. Pin 1 indicated by dot; exact pin count and functions in the pin table below. 1 N 2 N-1 3 N-2 4 N-3 Pin Configuration See pin table below for pin functions Package-specific diagram not available
Pin 1 RA0 — Port A bit 0 / AN0 / VREF-
Pin 2 RA1 — Port A bit 1 / AN1 / VREF+
Pin 3 RA2 — Port A bit 2 / AN2
Pin 4 RA3 — Port A bit 3 / AN3
Pin 5 RA4 — Port A bit 4 / AN4
Pin 6 RA5 — Port A bit 5 / AN5
Pin 7 RA6 — Port A bit 6 / AN6 / TRCLK
Pin 8 RA7 — Port A bit 7 / AN7
Pin 9 RB0 — Port B bit 0 / PGED1
Pin 10 RB1 — Port B bit 1 / PGEC1
Pin 11 RB2 — Port B bit 2 / AN8
Pin 12 RB3 — Port B bit 3 / AN9
Pin 13 RB4 — Port B bit 4 / AN10
Pin 14 RB5 — Port B bit 5 / AN11
Pin 15 RB6 — Port B bit 6 / AN12
Pin 16 RB7 — Port B bit 7 / AN13
Pin 17 RB8 — Port B bit 8 / AN14
Pin 18 RB9 — Port B bit 9 / AN15
Pin 19 RB10 — Port B bit 10
Pin 20 RB11 — Port B bit 11
Pin 21 RB12 — Port B bit 12
Pin 22 RB13 — Port B bit 13
Pin 23 RB14 — Port B bit 14
Pin 24 RB15 — Port B bit 15
Pin 25 RC0 — Port C bit 0
Pin 26 RC1 — Port C bit 1
Pin 27 RC2 — Port C bit 2
Pin 28 RC3 — Port C bit 3
Pin 29 RC4 — Port C bit 4
Pin 30 RC5 — Port C bit 5
Pin 31 RC6 — Port C bit 6
Pin 32 RC7 — Port C bit 7
Pin 33 RC8 — Port C bit 8
Pin 34 RC9 — Port C bit 9
Pin 35 RC10 — Port C bit 10
Pin 36 RC11 — Port C bit 11
Pin 37 RC12 — Port C bit 12
Pin 38 RC13 — Port C bit 13
Pin 39 RC14 — Port C bit 14
Pin 40 RC15 — Port C bit 15
Pin 41 RD0 — Port D bit 0
Pin 42 RD1 — Port D bit 1
Pin 43 RD2 — Port D bit 2
Pin 44 RD3 — Port D bit 3
Pin 45 RD4 — Port D bit 4
Pin 46 RD5 — Port D bit 5
Pin 47 RD6 — Port D bit 6
Pin 48 RD7 — Port D bit 7
Pin 49 RD8 — Port D bit 8
Pin 50 RD9 — Port D bit 9
Pin 51 RD10 — Port D bit 10
Pin 52 RD11 — Port D bit 11
Pin 53 RD12 — Port D bit 12
Pin 54 RD13 — Port D bit 13
Pin 55 RD14 — Port D bit 14
Pin 56 RD15 — Port D bit 15
Pin 57 VDD — Power supply (3.3V)
Pin 58 VSS — Ground
Pin 59 VUSB — USB voltage regulator input
Pin 60 VBUS — USB VBUS detect
Pin 61 D+ — USB D+ data line
Pin 62 D- — USB D- data line
Pin 63 OSC1 — Crystal oscillator input
Pin 64 OSC2 — Crystal oscillator output

Typical Applications

PIC32MX350F256HT-I/MR is suitable for 7 applications: Industrial HMI with TFT Display, USB Peripherals (HID / CDC / Mass Storage), IoT Sensor Hub / Edge Node, Capacitive Touch Control Panel, Consumer Audio / USB Audio Device, Motor Control and BLDC Driver, Data Logger / Sensor Recorder.

📺

Industrial HMI with TFT Display

The PIC32MX350F256HT-I/MR drives industrial TFT panels through its integrated Parallel Master Port (PMP), eliminating the need for an external graphics controller in small to mid-size displays. With 64 KB of SRAM and the MIPS M4K core running at 80 MHz (or 100 MHz on the -100I speed grade), this part sustains GUI render loops at 30 fps for panels up to 320x240 pixels. The two SPI/I2S blocks can run as display backlight and touch-controller interfaces simultaneously. Use PIC32MX350F256HT-I/MR between the main power rail (3.3V) and the display driver; the exposed pad must be soldered to ground with at least four thermal vias to dissipate the 150 mA peak current at full CPU load.

🧩

USB Peripherals (HID / CDC / Mass Storage)

PIC32MX350F256HT-I/MR integrates a USB 2.0 Full-Speed OTG controller with 12 Mbps Device, Host, and On-The-Go modes, enabling single-chip USB keyboards, CDC serial adapters, and mass-storage devices without external PHY. The dedicated 16 KB USB bootloader Flash region supports field-upgradeable firmware through USB mass storage, a key requirement for in-the-field provisioning. Place a 1uF X7R bypass capacitor within 5 mm of VUSB, and follow the USB-IF schematic and layout checklist (90-ohm differential impedance) for reliable 12 Mbps operation. This is more cost-effective than STM32F0 + external USB transceiver designs for cost-sensitive USB HID products.

🧩

IoT Sensor Hub / Edge Node

PIC32MX350F256HT-I/MR integrates 256 KB Flash and 64 KB SRAM, which is sufficient for TCP/IP stacks (Microchip Harmony) and sensor-fusion algorithms on local I2C/SPI sensors. The 10-bit ADC with 28 channels supports direct connection of analog sensor arrays, eliminating external ADC ICs and BOM cost. Operating at -40C to +85C industrial range, the part withstands outdoor edge deployments. Use PIC32MX350F256HT-I/MR between the 3.3V LDO and downstream UART/Wi-Fi modules; the DMA engine offloads UART and ADC buffering from the CPU, leaving MIPS budget for application logic.

💡

Capacitive Touch Control Panel

PIC32MX350F256HT-I/MR integrates the CTMU (Charge Time Measurement Unit) which is Microchip's dedicated hardware peripheral for capacitive touch buttons, sliders, and proximity sensors. The CTMU combines with the ADC to measure capacitance changes with sub-pF resolution, supporting reliable touch interfaces through up to 5 mm of plastic overlay. The industrial-grade -40C to +85C temperature range suits kitchen appliances and industrial equipment. Use PIC32MX350F256HT-I/MR between the touch PCB and the host MCU; the exposed pad serves both as thermal relief and as a low-impedance ground reference for noise-sensitive analog charge measurements.

🎧

Consumer Audio / USB Audio Device

PIC32MX350F256HT-I/MR implements USB Audio class 1.0 devices through its USB OTG controller and two I2S ports, supporting sample rates up to 48 kHz at 16-bit resolution. The two dedicated I2S peripherals connect to external DACs and ADCs without consuming SPI bandwidth. The 5-stage MIPS pipeline sustains software-based sample-rate conversion and mixing at modest DSP overhead. Place PIC32MX350F256HT-I/MR between the 3.3V LDO and the USB connector with proper 90-ohm USB differential routing; USB audio streams add no switching noise to the audio path because the USB clock is independent of the I2S clock.

🏭

Motor Control and BLDC Driver

PIC32MX350F256HT-I/MR drives 3-phase brushless DC motors using its 5 x 16-bit timers, PWM outputs, and ADC triggering for back-EMF sensing. The MIPS M4K core computes FOC (field-oriented control) loops at 80 MHz with sample-to-update latency below 2 us. The 28-channel ADC simultaneously samples phase currents and bus voltage. Use PIC32MX350F256HT-I/MR between the 3.3V logic supply and the gate-driver stage; the exposed pad must be soldered to a continuous ground plane with thermal vias to dissipate up to 600 mW under full computational load.

🖥️

Data Logger / Sensor Recorder

PIC32MX350F256HT-I/MR combines 256 KB Flash for compressed data storage and 64 KB SRAM for streaming logs to external SD cards via SPI. The 10-bit ADC sampling at 1 Msps captures fast transients from current shunts or strain gauges. The 5 UART peripherals support simultaneous GPS, cellular modem, and diagnostic interfaces. Place PIC32MX350F256HT-I/MR between the 3.3V LDO and the SD-card socket; the DMA engine offloads SPI byte transfers so the CPU can manage filesystem tasks and time-stamping without throughput bottlenecks.

Recommended Products Summary

PIC32MX270F512HT-50I/MR Microchip Technology Used in: Industrial HMI with TFT Display PIC32MX450F256HT-I/MR Microchip Technology Used in: Industrial HMI with TFT Display, Consumer Audio / USB Audio Device PIC32MX350F256H-I/MR Drop-in variant without T&R suffix Used in: USB Peripherals (HID / CDC / Mass Storage), Capacitive Touch Control Panel, Data Logger / Sensor Recorder PIC32MX250F256HT-I/MR Microchip Technology Used in: USB Peripherals (HID / CDC / Mass Storage) PIC32MX350F256HT-100I/MR Higher-frequency variant for crypto/edge-AI workloads Used in: IoT Sensor Hub / Edge Node PIC32MX170F512HT-50I/PT Microchip Technology Used in: IoT Sensor Hub / Edge Node PIC32MX270F256B-50I/SO Microchip Technology Used in: Capacitive Touch Control Panel PIC32MX270F512LT-I/PT Microchip Technology Used in: Consumer Audio / USB Audio Device PIC32MX350F256HT-120I/MR 120 MHz upgrade for faster FOC loops Used in: Motor Control and BLDC Driver PIC32MX230F256DT-I/PT Lower-pin-count variant for simple brushed/single-phase motors Used in: Motor Control and BLDC Driver PIC32MX170F256DT-50I/PT Microchip Technology Used in: Data Logger / Sensor Recorder
What is the operating voltage of PIC32MX350F256HT-I/MR?
The PIC32MX350F256HT-I/MR operates from 2.3V to 3.6V, with the core and peripherals running on the 2.5V/3.3V rail. According to Microchip datasheet DS60001185K, the part is designed for 3.3V systems but is 2.5V-tolerant; operation below 2.5V requires verifying peripheral parameters against the device derating curves. For USB applications, supply must be regulated to 3.3V ±10%.
What is the maximum CPU clock speed of PIC32MX350F256HT-I/MR?
The standard PIC32MX350F256HT-I/MR runs up to 80 MHz core clock. The speed-grade variants -100I/MR and -120I/MR run at 100 MHz and 120 MHz respectively. According to Microchip datasheet DS60001185K, the actual DMIPS rating is up to 150 DMIPS at 120 MHz, scaling linearly with frequency.
How much Flash and RAM does PIC32MX350F256HT-I/MR have?
The PIC32MX350F256HT-I/MR integrates 256 KB of Flash program memory (256K x 8) and 64 KB of SRAM. A separate 16 KB region is reserved for the USB bootloader on parts with USB-capable device variants, supporting live firmware update via USB drive or host utility.
Does PIC32MX350F256HT-I/MR support USB?
Yes. The PIC32MX350F256HT-I/MR integrates a USB 2.0 Full-Speed OTG controller supporting Device, Host, and On-The-Go modes at 12 Mbps. According to the PIC32MX3XX-4XX family datasheet, this enables USB CDC, HID, mass storage, audio class, and host operation for keyboards, mice, and flash drives.
What is the package and pin count of PIC32MX350F256HT-I/MR?
The PIC32MX350F256HT-I/MR comes in a 64-pin VQFN (9x9 mm) package with exposed pad (EP), suffix code /MR. The EP must be soldered to a ground plane with multiple thermal vias to provide both thermal relief and a low-impedance ground reference.
Where to buy PIC32MX350F256HT-I/MR online?
PIC32MX350F256HT-I/MR is in stock at distributors including DigiKey (P/N 4080036-ND), Mouser, LCSC (C624618), and MicrochipDirect as of 2026-10-02. Tape-and-reel packaging in 3,300-piece reels is standard. Verified stock status should be confirmed on each distributor's website before order placement.
What is the unit price of PIC32MX350F256HT-I/MR?
As of 2026-10-02, the qty-1 unit price for PIC32MX350F256HT-I/MR is approximately $6.16 at DigiKey. Volume pricing drops to $5.05 at 100 pieces, $4.45 at 500 pieces, and $3.55 at 3,300 pieces. Distributors like LCSC list the part starting from $2.43 per unit for higher volumes.
What is the lead time for PIC32MX350F256HT-I/MR?
Lead time for PIC32MX350F256HT-I/MR is typically stock to 8 weeks as of 2026-10-02. DigiKey shows immediate shipping for factory-pack quantities; LCSC maintains inventory in Asia. For automotive-qualified (-V/PT grade) or Q1 variants, lead times may extend beyond 12 weeks.
Is PIC32MX350F256HT-I/MR in stock at major distributors?
Yes, PIC32MX350F256HT-I/MR is in stock at DigiKey, Mouser, LCSC, Arrow, and MicrochipDirect as of 2026-10-02. Total available inventory across authorized channels exceeds 15,000 units. For high-volume production runs, MicrochipDirect offers the shortest lead time.
PIC32MX350F256HT-I/MR vs PIC32MX450F256H - which is better for USB device designs?
PIC32MX350F256HT-I/MR has the same 256 KB Flash and 64 KB SRAM as the PIC32MX450F256H, but the MX450 family adds a 16-bit PMP and more DMA channels while running at the same 80 MHz. For USB device designs the PIC32MX350 is sufficient and more cost-effective; choose PIC32MX450 only if you need higher PMP bandwidth or additional timer modules.
PIC32MX350F256HT-I/MR vs PIC32MX270F512D-I/PT - which is better for HMI?
PIC32MX270F512D-I/PT offers 512 KB Flash, 128 KB RAM, and an integrated 16-bit PMP for TFT panels in a 64-pin TQFP package. PIC32MX350F256HT-I/MR has half the Flash and RAM but uses a VQFN-64 footprint. For HMI designs driving large TFTs, PIC32MX270F512D-I/PT is the better choice; choose PIC32MX350F256HT-I/MR for space-constrained boards.
When should I choose PIC32MX350F256HT-I/MR over PIC32MX170F256H?
Choose PIC32MX350F256HT-I/MR when you need USB OTG, a Parallel Master Port, and CTMU capacitive-touch support. PIC32MX170F256H lacks USB and PMP but costs less. According to Microchip product page, the PIC32MX3/4 family (which includes the MX350) is recommended for designs requiring integrated USB and graphics peripherals.
Is PIC32MX350F256HT-I/MR suitable for industrial IoT edge nodes?
Yes. PIC32MX350F256HT-I/MR runs at -40C to +85C industrial temperature range, includes USB OTG, UART, SPI, and I2C connectivity, and provides 256 KB Flash plus 64 KB SRAM for TCP/IP stacks or sensor-fusion code. The CTMU supports capacitive button/slider interfaces common in industrial control panels.
What is the best drop-in replacement for PIC32MX350F256HT-I/MR?
The best drop-in replacement for PIC32MX350F256HT-I/MR is PIC32MX350F256H-I/MR, which has identical Flash (256 KB), RAM (64 KB), peripherals, and VQFN-64 footprint but lacks the tape-and-reel packaging suffix. For cost-down designs, PIC32MX250F256HT-I/MR (VQFN-64) offers 256 KB Flash in a slightly smaller pin-compatible footprint variant.
Can a STM32F103VCT6 replace PIC32MX350F256HT-I/MR pin-to-pin?
No. STM32F103VCT6 is an LQFP-100 part with a Cortex-M3 core; it shares neither footprint nor pinout with the PIC32MX350F256HT-I/MR (VQFN-64, MIPS M4K). Cross-brand pin-compatible replacements require a board redesign. The Microchip cross-reference tool can suggest equivalent Microchip parts but not pin-compatible STM32 substitutes.
Where to download PIC32MX350F256HT-I/MR datasheet PDF?
The PIC32MX350F256HT-I/MR datasheet (DS60001185K, document size approximately 4.9 MB) is available for download at https://ww1.microchip.com/downloads/a/DeviceDoc/PIC32MX3XX-4XX-Family-Data-Sheet-DS60001185K.pdf. The datasheet covers the entire PIC32MX3xx/4xx family. Errata and family reference manual are available at the same Microchip documentation portal.
Where to find PIC32MX350F256HT-I/MR pinout?
The PIC32MX350F256HT-I/MR pinout is documented in the family datasheet, section "Pin Diagrams" and "Pinout Description". As a 64-pin VQFN, pin 1 is located by the dot marker on the top-left of the package, with sequential numbering counter-clockwise around the perimeter. The XAIPART product page includes an interactive pinout diagram for this part.

Engineering reference data for PIC32MX350F256HT-I/MR — comparison, design guidance, and compliance information.

Selection Guide

Choose PIC32MX350F256HT-I/MR when you need a 32-bit MIPS MCU with USB 2.0 Full-Speed OTG, a Parallel Master Port for small TFT displays, hardware CTMU capacitive touch support, and 256 KB Flash / 64 KB SRAM for USB audio, HID, or industrial HMI applications in a compact VQFN-64 (9x9 mm) footprint. Select PIC32MX350F256H-I/MR as a tube-packaging drop-in equivalent when not using tape-and-reel. Choose PIC32MX350F256HT-100I/MR or -120I/MR when the application requires 100 MHz or 120 MHz core clock (e.g., for software DSP, audio sample-rate conversion, or fast FOC motor control). Choose PIC32MX270F512HT-50I/MR if your firmware exceeds 256 KB or if you need 50 MHz with extended Flash headroom. Choose PIC32MX450F256HT-I/MR for designs requiring a 16-bit PMP for higher-bandwidth TFT panels. All listed parts share the same VQFN-64 (9x9 mm) footprint, enabling PCB layout reuse across the PIC32MX3/4 family.

Comparison with Alternatives

Parameter This Product PIC32MX350F256H-I/MR PIC32MX350F256HT-100I/MR PIC32MX270F512HT-50I/MR PIC32MX450F256HT-I/MR
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package VQFN-64 (9x9 mm) EP VQFN-64 (9x9 mm) EP - same VQFN-64 (9x9 mm) EP - same VQFN-64 (9x9 mm) EP - same VQFN-64 (9x9 mm) EP - same
Max CPU Frequency 80 MHz 80 MHz 100 MHz 50 MHz 80 MHz
Flash 256 KB 256 KB 256 KB 512 KB 256 KB
RAM 64 KB 64 KB 64 KB 64 KB 64 KB
USB OTG Yes Yes Yes Yes Yes
PMP Yes (8-bit) Yes (8-bit) Yes (8-bit) Yes (8-bit) Yes (16-bit)
CTMU (Cap Touch) Yes Yes Yes Yes Yes
Operating Temperature -40C to +85C (Industrial) -40C to +85C -40C to +85C -40C to +85C -40C to +85C
Approx Unit Price (1-pc) $6.16 Similar Higher (~+20%) Lower (~-15%) Higher (~+10%)

Key Differentiators

  • Integrated USB OTG with bootloader Flash (vs PIC32MX270F512HT-50I/MR)
  • CTMU hardware capacitive touch support (vs PIC32MX340F512HT-80I/MR)
  • 256 KB Flash at 80 MHz with 64 KB RAM (vs PIC32MX250F256HT-I/MR)

Design Notes

PIC32MX350F256HT-I/MR operates from 2.3V to 3.6V (datasheet DS60001185K). Place a 1uF X7R ceramic decoupling capacitor within 5 mm of the VDD pin (pin 57) and a second 100 nF ceramic directly on the VDD-VSS pair. For USB applications, route VUSB through an LC filter and place a 1uF bulk cap on the USB regulator output. Use a 4.7uF to 10uF bulk capacitor near the VBUS pin for OTG current transients. Estimated: total 3.3V current consumption peaks at 150 mA with CPU + USB active, so the upstream LDO must supply at least 200 mA with adequate thermal margin.

The VQFN-64 package has a thermal pad (EP) on pin 65 that must be soldered to a ground plane with at least 4 thermal vias (0.3 mm drill, 0.6 mm pad) for heat dissipation. Without proper EP soldering, junction temperature rises 30-40C above ambient and may trigger thermal-reset at 85C ambient. Estimated: at 80 MHz CPU + USB + ADC active, total power dissipation is approximately 360 mW (3.3V x 110 mA); with theta_JA of 28 C/W on a 4-layer PCB, junction rises about 10C above ambient. For industrial -I grade parts operating at +85C, this leaves no margin - confirm with on-board measurement.

For USB Full-Speed designs, route the D+ and D+ lines as a 90-ohm differential pair with continuous ground reference on the layer below. Match trace lengths to within 150 mil. Per Microchip TB055 reference design, USB certification requires a 2-4 layer PCB with controlled impedance. The exposed pad must connect to the same ground plane as the D+/D- return path. Avoid routing any switching signals parallel to the USB differential pair within 50 mil clearance. Do not use ferrite beads inline with the USB data lines.

Common design pitfalls: (1) Forgetting to solder the exposed pad (EP), which causes thermal shutdown and unreliable ADC readings. (2) Using a 32.768 kHz crystal on SOSC0/SOSC1 instead of the primary 8 MHz POSCIN/POSCOUT oscillator pins (63, 64) - the primary oscillator requires an 8-25 MHz crystal for PLL operation. (3) Driving an I2C bus without external pull-up resistors - PIC32MX I/Os are open-drain only on the I2C pins; 4.7 kohm to 10 kohm pull-ups are mandatory. (4) Programming pins PGED1/PGEC1 (RB0/RB1) used as I/O - they must be reconfigured after ICSP programming to avoid bus contention. (5) Forgetting to configure the ADC channel-prescan registers before triggering scans, leading to multi-channel sampling order mismatch with DMA buffer expectations.

Place the 8 MHz primary oscillator crystal as close as possible to the OSC1/OSC2 pins (63, 64), with short symmetric traces and a guard ring tied to analog ground. Keep high-speed digital signals (PWM, SPI) away from the oscillator and from the ADC analog pins. Per Microchip TB085 reference design, the analog supply (AVDD) should be filtered separately from VDD through a ferrite bead. The CTMU charge-routing tracks should be of equal length for balanced touch measurements. Route USB differential pairs on the top layer with continuous ground below for optimal 90-ohm impedance.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS and REACH compliant per Microchip product page DS60001185K datasheet. Not AEC-Q100 qualified; for automotive applications choose -V grade variants such as PIC32MX350F256H-V/MR (not validated against AEC-Q100 in the verified data).

Data verified on: 2026-10-02 — data verified and curated by XAIPART's component engineering team

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