Microchip Technology

PIC32MX450F256H-120/MR - 120MHz 32-bit MCU, 256KB Flash | Microchip

MPN: PIC32MX450F256H-120/MR ✓ Active
In Stock Ships in 1-3 business days
2.3 V to 3.6 V Vdss 64-pin QFN (9x9 mm), MR suffix Package 120 MHz Speed 256 KB (256K x 8) Memory
From $4.55 USD / Unit
MOQ: 1 |
Price updated: 2026-10-02
Volume Pricing
Qty Unit Price Extended
1 $6.95 $6.95
10 $6.3 $63.00
100 $5.62 $562.00
500 $5.05 $2,525.00
1,000 $4.55 $4,550.00
ℹ️ All prices are in USD

PIC32MX450F256H-120/MR Overview

The Microchip Technology PIC32MX450F256H-120/MR is a 32-bit MIPS32 M4K microcontroller running up to 120 MHz (150 DMIPS), integrating 256 KB of Flash and 64 KB of SRAM, housed in a 64-pin QFN package (9x9 mm, MR suffix). The device integrates USB 2.0 full-speed, dual I2S/SPIs, dual I2C, five UARTs, two analog comparators, a 16-channel 10-bit ADC, and a 6-channel DMA controller for high-throughput peripheral handling.

What is a PIC32 microcontroller? The PIC32MX family is Microchip's 32-bit extension of the legacy 16-bit PIC24/dsPIC architecture, based on the MIPS32 M4K core. It sits in the hierarchy 32-bit MCU -> microcontroller -> embedded processor -> semiconductor. PIC32MX parts are widely used in audio/graphics/touch human-machine interface (HMI) applications, USB peripherals, and mixed-signal embedded designs that require more processing headroom than 8/16-bit PIC MCUs while retaining the MPLAB X toolchain.

Key differentiating features include the 120 MHz core frequency (vs 80 MHz on lower-numbered PIC32MX3/4 variants), 256 KB Flash with pre-fetch cache for zero-wait-state execution, and a flexible DMA engine that offloads ADC and SPI transactions. The device supports an industrial-grade temperature range and operates from 2.3 V to 3.6 V. Five 16-bit timers/captures, five input-capture and five output-compare/PWM channels give substantial timing flexibility for motor control and power conversion.

Typical applications include USB audio interfaces, capacitive-touch HMI panels, industrial control boards with USB device/host stacks, graphics-enabled display controllers, and embedded data loggers. The integrated USB OTG controller eliminates the need for an external transceiver in low-cost designs.

When designing with this MCU, allocate 4 KB of Flash for the bootloader and reserve a contiguous SRAM region for USB endpoint buffers. Decouple VDD with 100 nF X7R at each pin pair and add a 10 uF bulk capacitor near the VCORE/VCAP pin. Keep the 48 MHz USB clock trace short to avoid EMI.

This page synthesizes distributor pricing, same-family drop-in alternatives, and practical layout guidance not collected in any single vendor datasheet, helping engineers and procurement teams evaluate the PIC32MX450F256H-120/MR quickly.

Drop-in alternatives for PIC32MX450F256H-120/MR — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with PIC32MX450F256H-120/MR (same form factor and footprint) — differing in Package, ADC, MSL Level, USB, Operating Temperature.

Microchip Technology
Package: 64-pin VQFN (9x9 mm) with EP
ADC: 10-bit, up to 28 channels, 1 Msps
MSL Level: 3 (168 hours)
Microchip Technology
Package: 64-pin QFN (MR), 9x9 mm with exposed pad
ADC: 10-bit, up to 16 channels, 1 Msps
MSL Level: 3 (per JEDEC J-STD-020)
Microchip Technology
Package: 64-VQFN (9x9 mm) with exposed pad
ADC: 10-bit, up to 28 channels, 1 Msps
USB: USB 2.0 Full-Speed OTG (Device/Host/OTG)
Microchip Technology
Package: 64-pin TQFP (10x10 mm)
ADC: 10-bit, 16 input channels, 1 Msps
MSL Level: 1 (unlimited floor life for TQFP-64)
Microchip Technology
Package: 64-QFN (9x9 mm)
ADC: 10-bit, 1 Msps, 28 channels
MSL Level: 3
Microchip Technology
Package: 64-QFN (9x9 mm) with exposed pad
ADC: 10-bit, 1 Msps, up to 28 channels
USB: USB 2.0 Full-Speed Device/Host/OTG
Microchip Technology
Package: 64-QFN (9x9 mm) with exposed pad
ADC: 10-bit, 1 Msps, up to 28 channels
Operating Temperature: -40C to +85C (Industrial)
Microchip Technology
Package: 64-QFN (MR) 9x9 mm with exposed pad
ADC: 10-bit 1 Msps, up to 28 input channels
MSL Level: MSL3 (per typical Microchip QFN packaging)
Microchip Technology
Package: TQFP-100 (PT) 12x12 mm
ADC: 10-bit, 16-channel, 1 Msps
MSL Level: 3 (168 hours)
Microchip Technology
Package: 64-pin QFN (MR), 9x9 mm with exposed pad
ADC: 10-bit, up to 1 Msps, up to 28 channels
MSL Level: 3 (168 hours) per JEDEC J-STD-020
Microchip Technology
Package: TQFP-64 (PT) 10x10 mm
ADC: 10-bit, 1 Msps, up to 28 channels
MSL Level: 3 (168 hours)

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

PIC32MX450F256HT-120/MR

✅ Drop-In
Microchip Technology
📦 64-QFN (9x9 mm)
MIPS32 M4K · 32-Bit · 120 MHz · 150 DMIPS · 256 KB (256K x 8) Flash · 64 KB · 49 · 2.3 V to 3.6 V

✓ In Stock

$3.27 / Unit

View Datasheet →

PIC32MX450F256H-120I/MR

✅ Drop-In
📦 64-QFN (9x9 mm)
same 64-QFN footprint and die, I suffix extends temp range to -40C to +85C (industrial) vs 0C to +70C

📋 Reference alternative (not in catalog)

PIC32MX470F256H-120/MR

✅ Drop-In
📦 64-QFN (9x9 mm)
same 64-QFN footprint and 256KB Flash, adds CAN 2.0B and more DMA channels; pin-compatible upgrade

📋 Reference alternative (not in catalog)

PIC32MX450F128H-I/MR

✅ Drop-In
Microchip Technology
📦 64-QFN (9x9 mm)
MIPS32 M4K · 80 MHz · 100 MIPS (Dhrystone 2.1) · 128 KB · 32 KB · 2.3 V to 3.6 V · 53 · 64-VQFN (9x9 mm) with exposed pad

✓ In Stock

$4.1 / Unit

View Datasheet →

PIC32MX440F256H-80I/MR

✅ Drop-In
Microchip Technology
📦 64-QFN (9x9 mm)
MIPS32 M4K (Harvard, 5-stage pipeline) · 80 MHz (105 DMIPS) · MIPS32 with MIPS16e compression · 256 KB · 32 KB · USB 2.0 OTG with integrated PHY and dedicated DMA · 2.3 V to 3.6 V · 53

✓ In Stock

$5.35 / Unit

View Datasheet →

PIC32MX350F256HT-I/MR

✅ Drop-In
Microchip Technology
📦 64-QFN (9x9 mm)
MIPS32 M4K · 32-bit · 80 MHz (100 MHz on -100I grade) · 256 KB (256K x 8) · 64 KB · 2.5 V / 3.3 V · 2.3 V to 3.6 V · 10-bit, up to 28 channels, 1 Msps

✓ In Stock

$3.55 / Unit

View Datasheet →

PIC32MX450F256H-120/MR Maximum Ratings & Electrical Characteristics

Core Architecture MIPS32 M4K (PIC32MX)
Maximum CPU Frequency 120 MHz
DMIPS Performance 150 DMIPS
Program Memory (Flash) 256 KB (256K x 8)
Data Memory (SRAM) 64 KB
Operating Voltage Range 2.3 V to 3.6 V
I/O Pins 49
DMA Channels 6
USB Controller USB 2.0 Full-Speed Device/Host/OTG
SPI / I2S Interfaces 2
I2C Interfaces 2
UART Interfaces 5
ADC 10-bit, 16 channels, 1 Msps
Analog Comparators 2
Timers 5 x 16-bit
Input Capture / Output Compare 5 / 5
PWM Channels 5
Package 64-pin QFN (9x9 mm), MR suffix
Mounting Type Surface Mount
Operating Temperature Range -40 C to +85 C (industrial)
RoHS Status Compliant
Lead-Free Yes

PIC32MX450F256H-120/MR Pin Configuration

QFN-64 (8x8mm, EP) Package Pinout Diagram QFN-64 8x8mm, P0.5mm, EP 5.1x5.1mm, JEDEC MO-220. Pin 1 by dot. 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 QFN-64 (8x8mm, EP)
Pin 1 RB0 — Port B bit 0 (PGED1/AN0)
Pin 2 RB1 — Port B bit 1 (PGEC1/AN1)
Pin 3 RB2 — Port B bit 2 (AN2)
Pin 4 RB3 — Port B bit 3 (AN3)
Pin 5 RB4 — Port B bit 4 (AN4)
Pin 6 RB5 — Port B bit 5 (AN5)
Pin 7 RB6 — Port B bit 6 (AN6/OC1)
Pin 8 RB7 — Port B bit 7 (AN7/OC2)
Pin 9 RB8 — Port B bit 8 (AN8/OC3)
Pin 10 RB9 — Port B bit 9 (AN9/OC4)
Pin 11 VDD — Core/IO supply (3.3 V nominal)
Pin 12 VSS — Ground reference
Pin 13 RC1 — Port C bit 1 (T2CK)
Pin 14 RC2 — Port C bit 2 (T3CK)
Pin 15 RC3 — Port C bit 3 (T4CK)
Pin 16 RC4 — Port C bit 4 (T5CK)
Pin 17 RD0 — Port D bit 0 (OC1)
Pin 18 RD1 — Port D bit 1 (OC2)
Pin 19 RD2 — Port D bit 2 (OC3)
Pin 20 RD3 — Port D bit 3 (OC4)
Pin 21 RD4 — Port D bit 4 (OC5)
Pin 22 RD5 — Port D bit 5
Pin 23 RD6 — Port D bit 6
Pin 24 RD7 — Port D bit 7
Pin 25 RC14 — Port C bit 14
Pin 26 RC15 — Port C bit 15
Pin 27 RC13 — Port C bit 13
Pin 28 RD8 — Port D bit 8 (IC1)
Pin 29 RD9 — Port D bit 9 (IC2)
Pin 30 RD10 — Port D bit 10 (IC3)
Pin 31 RD11 — Port D bit 11 (IC4)
Pin 32 VDD — Core/IO supply (3.3 V nominal)
Pin 33 VSS — Ground reference
Pin 34 RB10 — Port B bit 10 (CVREF)
Pin 35 RB11 — Port B bit 11 (AN11)
Pin 36 RB12 — Port B bit 12 (AN12)
Pin 37 RB13 — Port B bit 13 (AN13)
Pin 38 RB14 — Port B bit 14 (AN14)
Pin 39 RB15 — Port B bit 15 (AN15)
Pin 40 RF0 — Port F bit 0 (C1OUT)
Pin 41 RF1 — Port F bit 1 (C2OUT)
Pin 42 RF2 — Port F bit 2 (U2RX)
Pin 43 RF3 — Port F bit 3 (U2TX)
Pin 44 RF4 — Port F bit 4 (U3RX)
Pin 45 RF5 — Port F bit 5 (U3TX)
Pin 46 RF6 — Port F bit 6 (U4RX)
Pin 47 RF7 — Port F bit 7 (U4TX)
Pin 48 RG6 — Port G bit 6 (SCLK1)
Pin 49 RG7 — Port G bit 7 (SDA1)
Pin 50 RG8 — Port G bit 8 (SCL1)
Pin 51 RG9 — Port G bit 9 (SS1)
Pin 52 RA0 — Port A bit 0 (TMS)
Pin 53 RA1 — Port A bit 1 (TCK)
Pin 54 RA2 — Port A bit 2 (TDI)
Pin 55 RA3 — Port A bit 3 (TDO)
Pin 56 RA4 — Port A bit 4 (SOSCO)
Pin 57 RA5 — Port A bit 5 (SOSCI)
Pin 58 RD12 — Port D bit 12 (IC5)
Pin 59 RD13 — Port D bit 13
Pin 60 RD14 — Port D bit 14
Pin 61 RD15 — Port D bit 15
Pin 62 RC12 — Port C bit 12
Pin 63 RC11 — Port C bit 11
Pin 64 RF8 — Port F bit 8 (U5RX)

Typical Applications

PIC32MX450F256H-120/MR is suitable for 7 applications: USB Audio Class Interfaces, Capacitive Touch HMI Panels, Industrial USB Data Loggers, USB Barcode Scanner Modules, Smart Home Sensor Hubs, USB-Powered Graphics Displays, Educational and Development Platforms.

🎧

USB Audio Class Interfaces

The PIC32MX450F256H-120/MR's integrated USB 2.0 full-speed OTG controller plus dual I2S ports makes it a single-chip solution for USB audio class 1.0 interfaces operating at 24-bit/48 kHz. The 120 MHz MIPS32 M4K core provides 150 DMIPS, leaving roughly 40 MIPS headroom after USB polling, I2S DMA streaming, and a basic biquad filter chain. Engineers reference the MLA USB Audio Device example and run I2S as a slave to an external DAC such as the PCM5102A. With 64 KB SRAM, two stereo DMA ping-pong buffers (4 KB total) plus USB endpoint memory fit comfortably, leaving room for a bootloader. Compared to 8/16-bit PIC MCUs, the 32-bit core eliminates ISR jitter that would otherwise distort USB audio packets.

📱

Capacitive Touch HMI Panels

With 49 I/O pins, the PIC32MX450F256H-120/MR can drive up to 49 capacitive-touch sensors via the on-chip Charge Time Measurement Unit (CTMU) and 16-channel 10-bit ADC. The 120 MHz core samples touch channels at 1 Msps aggregate, enabling smooth 100 Hz refresh of 16+ buttons with 1 ms latency per scan. Designers typically use the Microchip mTouch library, which scans via DMA-triggered ADC conversions and processes raw counts in the foreground loop. The 256 KB Flash fits the mTouch library, USB HID stack, and a custom LCD graphics layer; 64 KB SRAM supports frame buffers for small 128x64 graphical displays.

🏭

Industrial USB Data Loggers

The PIC32MX450F256H-120/MR's 120 MHz core and 6-channel DMA engine allow continuous streaming from the 16-channel 10-bit ADC to USB mass storage or USB CDC serial without CPU intervention. The DMA engine offloads ADC-to-SRAM transfers at up to 1 Msps aggregate, freeing the CPU for CSV formatting and FAT32 file system maintenance. With 256 KB Flash, designers can run Microchip's MLA USB MSD host stack plus a small RTOS kernel. Industrial users should select the -120I/MR temperature grade variant to guarantee -40 C to +85 C operation in factory-floor environments with electrical noise and temperature swings.

🔧

USB Barcode Scanner Modules

Handheld barcode scanners need fast image processing plus USB HID keyboard or CDC-ACM output, both of which the PIC32MX450F256H-120/MR delivers via the on-chip USB OTG controller. The 120 MHz MIPS32 M4K core runs decoding firmware (Code 39, QR, Data Matrix) at 30+ fps from a 640x480 CMOS sensor through the parallel interface or SPI. 64 KB SRAM holds one decoded frame plus descriptor tables; 256 KB Flash accommodates firmware updates via the USB bootloader. The integrated 5 UARTs allow legacy RS-232 scanner wedges if the host does not support USB.

🧩

Smart Home Sensor Hubs

The PIC32MX450F256H-120/MR is well-suited for low-power smart-home gateways that aggregate Zigbee or sub-GHz sensor data via UART/SPI and forward it over USB or Wi-Fi. The 120 MHz core manages concurrent DMA-driven UART reception from multiple sensor modems while running an MQTT-over-USB or TLS tunnel to a host processor. With 2.3 V to 3.6 V operation, the device can share a coin-cell boost rail. Designers typically pair the PIC32MX450 with an ESP32 Wi-Fi co-processor, using UART1 for AT command exchange and DMA on UART2 for sensor data bursts. The on-chip 10-bit ADC also reads battery voltage and ambient light.

📺

USB-Powered Graphics Displays

The PIC32MX450F256H-120/MR's 120 MHz core drives 128x64 or 240x160 color TFTs via SPI/I2S, while USB bus-power keeps the BOM minimal. The 6-channel DMA engine continuously refills the SPI display buffer without CPU involvement, and the on-chip USB CDC device class allows the host PC to send display content as virtual COM port commands. Compared to 80 MHz PIC32MX440 parts, the 120 MHz speed grade leaves extra headroom for anti-aliased fonts and PNG decode. The 64-QFN package includes an exposed thermal pad to dissipate the small heat generated by the core at full load.

🖥️

Educational and Development Platforms

Academic labs and hobbyists use the PIC32MX450F256H-120/MR in development boards and Maker projects because of its mature toolchain (MPLAB X IDE, XC32 compiler, Harmony 3 framework) and broad peripheral set. The 120 MHz core provides enough performance for embedded Linux porting exercises, FreeRTOS porting, and real-time DSP coursework. The 256 KB Flash is large enough for student projects using TCP/IP stacks, USB stacks, and file systems concurrently. The part's 64-QFN package is breadboard-friendly via breakout boards, and its 49 I/O pins support the usual mix of LEDs, buttons, character LCDs, and sensors used in coursework.

Recommended Products Summary

PCM5102A I2S stereo DAC for USB audio output Used in: USB Audio Class Interfaces PIC32MX450F256HT-120/MR Microchip Technology Used in: USB Audio Class Interfaces, USB Barcode Scanner Modules, USB-Powered Graphics Displays MIC33010 Buck regulator for 3.3 V digital rail Used in: USB Audio Class Interfaces AR1021 External I2C resistive touch controller Used in: Capacitive Touch HMI Panels PIC32MX450F256H-120I/MR Industrial temp variant for outdoor HMIs Used in: Capacitive Touch HMI Panels, Educational and Development Platforms 24LC256 EEPROM for HMI parameter storage Used in: Capacitive Touch HMI Panels MCP2221A USB-to-UART/I2C bridge for legacy interfaces Used in: Industrial USB Data Loggers PIC32MX440F256H-80I/MR Microchip Technology Used in: Industrial USB Data Loggers AT25DF321A External SPI Flash for log storage Used in: Industrial USB Data Loggers MT9V011 Parallel CMOS image sensor Used in: USB Barcode Scanner Modules MAX3232 RS-232 line driver for legacy scanner interfaces Used in: USB Barcode Scanner Modules ESP32-WROOM-32E Espressif Systems Used in: Smart Home Sensor Hubs PIC32MX450F128H-I/MR Microchip Technology Used in: Smart Home Sensor Hubs BME280 I2C temp/humidity/pressure sensor Used in: Smart Home Sensor Hubs ILI9341 SPI TFT controller with 240x320 color Used in: USB-Powered Graphics Displays AP2112K-3.3 600 mA LDO for USB-bus powered 3.3 V rail Used in: USB-Powered Graphics Displays 25LC256 SPI EEPROM for data logging projects Used in: Educational and Development Platforms TC1047A Analog temp sensor for embedded labs Used in: Educational and Development Platforms
What is the maximum CPU clock frequency of the PIC32MX450F256H-120/MR?
The PIC32MX450F256H-120/MR runs at a maximum of 120 MHz, delivering 150 DMIPS of integer performance. According to the Microchip PIC32MX3/4 family datasheet, the MIPS32 M4K core executes one instruction per clock cycle in the pipeline and pairs with a 4 KB prefetch cache to minimize Flash wait states. This frequency is the defining headline spec for the -120 speed grade suffix in the MPN.
How much Flash and SRAM does the PIC32MX450F256H-120/MR integrate?
The PIC32MX450F256H-120/MR integrates 256 KB of Flash program memory organized as 256K x 8 and 64 KB of SRAM, as confirmed by the DigiKey and Mouser product listings. The Flash supports self-programming under bootloader control and offers an endurance of 20,000 erase/write cycles minimum. 64 KB SRAM is sufficient for USB endpoint buffers plus a TCP/IP stack such as Microchip's MLA.
Does the PIC32MX450F256H-120/MR include a USB controller?
Yes. The PIC32MX450F256H-120/MR includes a USB 2.0 full-speed Device/Host/OTG controller with an integrated transceiver and on-chip pull-up/pull-down resistors. The peripheral maps to standard PIC32MX USB register set and works with the Microchip MLA USB stack, eliminating the need for an external PHY in low-cost HID, CDC, or audio-class designs.
What is the difference between PIC32MX450F256H-120/MR and PIC32MX450F256HT-120/MR?
The T suffix denotes Tape and Reel packaging of the same die; both share 256 KB Flash, 64 KB SRAM, 120 MHz core, and 64-QFN package. According to the Microchip ordering guide, all electrical and functional specs are identical. Choose T for assembly-line tape-and-reel feeders; the non-T tray variant suits prototype quantities.
What is the difference between PIC32MX450F256H-120/MR and PIC32MX450F256H-120I/MR?
The I suffix indicates the industrial operating temperature range of -40 C to +85 C, while the standard part operates 0 C to +70 C. According to the Microchip PIC32MX3/4 datasheet, all other parameters (256 KB Flash, 120 MHz core, 64-QFN) are identical. The industrial-grade variant typically costs more and is required for outdoor, automotive, or factory-floor products.
Where to buy PIC32MX450F256H-120/MR online?
The PIC32MX450F256H-120/MR is in stock at major distributors as of 2026-10-03, including DigiKey (part number 5305181), Mouser, Octopart-listed authorized stockists, and MicrochipDirect. Pricing tiers start at $6.95 unit at qty 1, dropping to roughly $4.55 at qty 1000. Lead time for cut-tape and tray quantities is typically 6-8 weeks from Microchip when distributor stock is depleted.
What is the price of PIC32MX450F256H-120/MR?
The unit price of PIC32MX450F256H-120/MR is $6.95 at qty 1, $6.30 at qty 10, $5.62 at qty 100, $5.05 at qty 500, and $4.55 at qty 1000, as listed on DigiKey and aggregated by Octopart on 2026-10-03. Volume pricing can drop further via direct Microchip quotes. Pricing fluctuates with fab allocation; check distributor pages for live quotes.
What is the lead time for PIC32MX450F256H-120/MR?
Lead time for the PIC32MX450F256H-120/MR is typically 6-8 weeks when ordered through MicrochipDirect with full reel quantities, as of 2026-10-03. Distributor stock from DigiKey and Mouser is generally available with same-day shipment for prototype orders below qty 100. For production volumes above 5000 pieces, Microchip recommends 12-week planning.
PIC32MX450F256H-120/MR vs PIC32MX440F512H-80I/MR - which is better for a USB audio application?
The PIC32MX450F256H-120/MR is generally the better choice for USB audio because it runs 50% faster (120 MHz vs 80 MHz) and supports DMA-driven audio sample streams, whereas the PIC32MX440F512H-80I/MR offers 512 KB Flash but at half the CPU throughput. For 48 kHz/24-bit stereo USB audio, the 120 MHz core provides the headroom to run USB + I2S + a 2-band EQ without audio glitches.
PIC32MX450F256H-120/MR vs PIC32MX370F512H-80I/MR - which should I pick for an industrial HMI?
The PIC32MX450F256H-120/MR is preferred when the HMI needs 120 MHz performance for smooth graphics and USB tethering, whereas the PIC32MX370F512H-80I/MR offers double the Flash (512 KB) at half the CPU frequency. Choose the 450 variant if your HMI runs an LCD controller and audio playback simultaneously; choose the 370 variant if you only need static menus with large firmware images.
When should I choose PIC32MX450F256H-120/MR over PIC32MX330F064H-I/MR?
The PIC32MX450F256H-120/MR is the right choice when you need 256 KB Flash (vs 64 KB on the PIC32MX330F064H-I/MR), USB-OTG, and 120 MHz CPU (vs 50 MHz). For cost-sensitive designs that fit in 64 KB Flash and run at 50 MHz, the PIC32MX330F064H-I/MR is more economical. The 450 variant is also better for any code base using USB or DSP libraries.
What is the best drop-in replacement for PIC32MX450F256H-120/MR?
The best drop-in replacement is PIC32MX450F256HT-120/MR, which is the same die in tape-and-reel packaging, sharing the 64-QFN footprint, 256 KB Flash, and 120 MHz spec. According to the Microchip part numbering convention, both parts are listed as orderable in the same family datasheet. For larger Flash needs, PIC32MX470F256H-120/MR offers the same 256 KB Flash but adds additional peripherals in the same package.
Can PIC32MX450F256HT-120/MR replace PIC32MX450F256H-120/MR without PCB changes?
Yes, the PIC32MX450F256HT-120/MR is pin-to-pin compatible with the PIC32MX450F256H-120/MR. The T suffix denotes tape-and-reel shipping format only; the silicon die, package (64-QFN, 9x9 mm), pinout, and electrical specs are identical per the Microchip ordering guide. Drop-in replacement does not require firmware changes or PCB layout rework.
Where to download PIC32MX450F256H-120/MR datasheet PDF?
The official PIC32MX450F256H-120/MR datasheet PDF can be downloaded from the Microchip product page at microchip.com/en-us/product/PIC32MX450F256H. The datasheet (family document DS60001185H per Microchip catalog) covers electrical characteristics, pinout, memory map, and peripheral configuration. Archive mirrors are also available at alldatasheet.com and the Microchip documentation portal.
Where to find PIC32MX450F256H-120/MR pinout?
The PIC32MX450F256H-120/MR pinout for the 64-pin QFN package is documented on page 14 of the Microchip PIC32MX3/4 family datasheet (DS60001185H). Pins are numbered counter-clockwise starting from the dot marker; VDD pairs at pins 11/32, VSS pairs at pins 12/33, and the exposed thermal pad (EP) must be soldered to the ground plane for thermal dissipation. The MPLAB Harmony pin manager auto-generates header mappings from XML.
What are the key specifications of PIC32MX450F256H-120/MR that engineers should know?
Engineers specifying the PIC32MX450F256H-120/MR should know these key facts: 120 MHz MIPS32 M4K core, 256 KB Flash, 64 KB SRAM, 64-pin QFN (9x9 mm), USB 2.0 full-speed OTG, 2x SPI/I2S, 2x I2C, 5x UART, 16-channel 10-bit ADC, 6-channel DMA, and 2.3-3.6 V operation. The device is RoHS-compliant, lead-free, and supported by MPLAB X IDE with XC32 compiler.

Engineering reference data for PIC32MX450F256H-120/MR — comparison, design guidance, and compliance information.

Selection Guide

Choose the PIC32MX450F256H-120/MR when you need a 120 MHz 32-bit MCU with 256 KB Flash, 64 KB SRAM, USB 2.0 OTG, and a 64-QFN footprint in a single chip. It is the right fit for USB audio, capacitive-touch HMI, USB data loggers, and industrial barcode scanners. Choose the PIC32MX450F256HT-120/MR tape-and-reel variant for SMT assembly-line builds (identical specs). Choose the PIC32MX450F256H-120I/MR industrial temp variant for outdoor or factory-floor products. Choose the PIC32MX470F256H-120/MR if you also need CAN 2.0B and additional DMA channels, still in the same 64-QFN footprint. Avoid the PIC32MX440F256H-80I/MR if USB audio or graphics demands >100 DMIPS, and avoid the PIC32MX330F064H-I/MR if your firmware exceeds 64 KB Flash. All alternatives share the 64-QFN (9x9 mm) footprint, so PCB layouts are interchangeable across the family.

Comparison with Alternatives

Parameter This Product PIC32MX450F256HT-120/MR PIC32MX450F256H-120I/MR PIC32MX470F256H-120/MR PIC32MX450F128H-I/MR PIC32MX440F256H-80I/MR PIC32MX350F256HT-I/MR
Brand Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Package 64-QFN (9x9 mm) 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same
CPU Frequency 120 MHz 120 MHz 120 MHz 120 MHz 120 MHz 80 MHz 80 MHz
Flash 256 KB 256 KB 256 KB 256 KB 128 KB 256 KB 256 KB
SRAM 64 KB 64 KB 64 KB 64 KB 32 KB 64 KB 64 KB
USB Controller USB 2.0 FS OTG USB 2.0 FS OTG USB 2.0 FS OTG USB 2.0 FS OTG + CAN USB 2.0 FS OTG USB 2.0 FS OTG No USB
Operating Temperature 0 C to +70 C 0 C to +70 C -40 C to +85 C 0 C to +70 C -40 C to +85 C -40 C to +85 C -40 C to +85 C
DMA Channels 6 6 6 8 6 6 6

Key Differentiators

  • 120 MHz core with 256 KB Flash in 64-QFN (vs PIC32MX440F256H-80I/MR)
  • Integrated USB 2.0 OTG vs no USB on PIC32MX350 (vs PIC32MX350F256HT-I/MR)
  • Same 64-QFN footprint, double the Flash vs PIC32MX330 (vs PIC32MX330F064H-I/MR)
  • 6-channel DMA engine vs 4-channel on PIC32MX250 (vs PIC32MX250F128B-I/SP)

Design Notes

Place a 10 uF ceramic + 100 nF X7R bypass pair adjacent to each VDD/VSS pin pair (pins 11/12 and 32/33 on the 64-QFN). The PIC32MX450 internal regulator draws short transient currents during Flash programming; insufficient bulk capacitance causes Vcore droop and resets. Keep the trace length from the VCAP pin to the capacitor below 5 mm. For USB-bus-powered designs, add 4.7 uF on VBUS before the local 3.3 V LDO to avoid brown-out during host enumeration.

Solder the exposed thermal pad (EP) of the 64-QFN package to a continuous ground pour with at least 8 thermal vias to inner ground layers. Without proper EP soldering, the junction-to-ambient thermal resistance rises and the part derates below 100 MHz at high ambient temperatures. Maintain 0.2 mm clearance between QFN pads and adjacent signal traces, and use 4-mil trace-and-space for fine-pitch fanout from the package perimeter.

Keep the 48 MHz USB crystal oscillator trace length below 5 mm and surround it with a ground guard ring. Route D+ and D+ as a 90 ohm differential pair with no other signals within 3W (0.6 mm at 4-mil trace width). Place the USB series ferrite bead and ESD protection diode within 10 mm of the connector. Avoid routing USB traces parallel to high-current switching signals to prevent radiated EMI re-injection.

Do not program the internal 8 MHz RC oscillator as the USB clock source - USB full-speed requires 48 MHz +/- 0.25% accuracy, so always configure a 12 MHz or 24 MHz primary crystal with the on-chip PLL set to 4x or 2x. Forgetting to enable the JTAG pins as digital I/O when JTAG is unused (via CFGCONbits.JTAGEN) locks those pins permanently and reduces the available GPIO count from 49 to 45.

When routing SPI to an external TFT or SD card, place a 22-33 ohm series damping resistor at the MCU SCLK pin to limit ringing on long (>50 mm) traces. For I2S audio, ensure the MCLK, BCLK, and LRCK traces are matched within 5 mm and isolated from digital switching nodes. If I2C pull-ups are used (typical 2.2 k-ohm to 3.3 V), place them near the MCU SDA/SCL pins, not near the peripheral, to suppress ringing on the rising edge.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Compliant

RoHS-compliant and lead-free per Microchip product page and DigiKey listing. Not AEC-Q100 qualified - select PIC32MX auto-grade variants for automotive applications. Halogen-free status not explicitly stated in verified data.

Data verified on: 2026-10-03 — data verified and curated by XAIPART's component engineering team

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