STMicroelectronics

STM32L452REY6TR - Ultra-low-power ARM Cortex-M4 MCU | STMicroelectronics

MPN: STM32L452REY6TR βœ“ Active
In Stock (99,999) Ships in 1-3 business days
1.71 V to 3.6 V Vdss 28 Β΅A (Stop 2) Id UFBGA-64 (Y6) Package 80 MHz Speed 512 KB Memory
$6.5 USD / Unit
MOQ: 1 |
Volume Pricing
Qty Unit Price Extended
1 $6.5 $6.50
10 $5.85 $58.50
100 $5.2 $520.00
500 $4.68 $2,340.00
1,000 $4.16 $4,160.00
ℹ️ All prices are in USD

Drop-in alternatives for STM32L452REY6TR β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

STM32L452REY6

βœ… Drop-In
πŸ“¦ UFBGA-64 (Y6)
Same package and pinout, non-tape-and-reel packaging

πŸ“‹ Reference alternative (not in catalog)

STM32L452REI6

βœ… Drop-In
πŸ“¦ UFBGA-64 (I6)
Same package and pinout, industrial temperature grade (-40 to +125C)

πŸ“‹ Reference alternative (not in catalog)

STM32L452REY6TR

βœ… Drop-In
STMicroelectronics
πŸ“¦ UFBGA-64 (Y6)
ARM Cortex-M4 with FPU Β· 80 MHz Β· 512 KB Β· 160 KB Β· 1.71 V to 3.6 V Β· 51 Β· UFBGA-64 (Y6) Β· -40C to +85C

βœ“ 99,999 In Stock

$4.16 / Unit

View Datasheet β†’
ℹ️ 2 cross-package part(s) hidden β€” different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

STM32L452REY6TR Maximum Ratings & Electrical Characteristics

Core ARM Cortex-M4 with FPU
Maximum Frequency 80 MHz
Flash Memory 512 KB
SRAM 160 KB
Operating Voltage 1.71 V to 3.6 V
GPIO Pins 51
Package UFBGA-64 (Y6)
Operating Temperature -40C to +85C
DMA Channels 12
ADC Resolution 12-bit
DAC Resolution 12-bit
Communication Interfaces USART, SPI, I2C, USB 2.0 FS, CAN
Low-Power Mode Current 28 Β΅A (Stop 2)
RoHS Status Compliant
Mounting Type Surface Mount

STM32L452REY6TR Pin Configuration

BGA-64 Package Pinout Diagram BGA-64 9x9mm, 8x8, P0.8mm, JEDEC MO-192. A1 BGA-64 8x8 grid
Pin 1 VDD β€” Digital power supply
Pin 2 VSS β€” Digital ground
Pin 3 PA0 β€” GPIO/ADC input
Pin 4 PA1 β€” GPIO/ADC input
Pin 5 PA2 β€” GPIO/USART2_TX
Pin 6 PA3 β€” GPIO/USART2_RX
Pin 7 PA4 β€” GPIO/SPI1_NSS
Pin 8 PA5 β€” GPIO/SPI1_SCK
Pin 9 PA6 β€” GPIO/SPI1_MISO
Pin 10 PA7 β€” GPIO/SPI1_MOSI
Pin 11 PB0 β€” GPIO/ADC input
Pin 12 PB1 β€” GPIO/ADC input
Pin 13 PB2 β€” GPIO
Pin 14 PB3 β€” GPIO/SWO
Pin 15 PB4 β€” GPIO
Pin 16 PB5 β€” GPIO
Pin 17 PB6 β€” GPIO/I2C1_SCL
Pin 18 PB7 β€” GPIO/I2C1_SDA
Pin 19 PB8 β€” GPIO/I2C1_SCL
Pin 20 PB9 β€” GPIO/I2C1_SDA
Pin 21 PB10 β€” GPIO/I2C2_SCL
Pin 22 PB11 β€” GPIO/I2C2_SDA
Pin 23 PB12 β€” GPIO/SPI2_NSS
Pin 24 PB13 β€” GPIO/SPI2_SCK
Pin 25 PB14 β€” GPIO/SPI2_MISO
Pin 26 PB15 β€” GPIO/SPI2_MOSI
Pin 27 PC0 β€” GPIO/ADC input
Pin 28 PC1 β€” GPIO/ADC input
Pin 29 PC2 β€” GPIO/ADC input
Pin 30 PC3 β€” GPIO/ADC input
Pin 31 PC4 β€” GPIO/ADC input
Pin 32 PC5 β€” GPIO/ADC input
Pin 33 PC6 β€” GPIO
Pin 34 PC7 β€” GPIO
Pin 35 PC8 β€” GPIO
Pin 36 PC9 β€” GPIO
Pin 37 PC10 β€” GPIO
Pin 38 PC11 β€” GPIO
Pin 39 PC12 β€” GPIO
Pin 40 PC13 β€” GPIO/RTC
Pin 41 PC14 β€” GPIO/OSC32_IN
Pin 42 PC15 β€” GPIO/OSC32_OUT
Pin 43 PH0 β€” OSC_IN
Pin 44 PH1 β€” OSC_OUT
Pin 45 NRST β€” Reset
Pin 46 VDD β€” Digital power supply
Pin 47 VSS β€” Digital ground
Pin 48 VDDA β€” Analog power supply
Pin 49 VSSA β€” Analog ground
Pin 50 VREF+ β€” ADC reference voltage
Pin 51 VREF- β€” ADC reference ground
Pin 52 PA8 β€” GPIO/USART1_CK
Pin 53 PA9 β€” GPIO/USART1_TX
Pin 54 PA10 β€” GPIO/USART1_RX
Pin 55 PA11 β€” GPIO/USB_DM
Pin 56 PA12 β€” GPIO/USB_DP
Pin 57 PA13 β€” SWDIO
Pin 58 PA14 β€” SWCLK
Pin 59 PA15 β€” GPIO/JTDI
Pin 60 PB3 β€” GPIO/JTDO
Pin 61 PB4 β€” GPIO/NJTRST
Pin 62 PB5 β€” GPIO
Pin 63 VDD β€” Digital power supply
Pin 64 VSS β€” Digital ground

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for STM32L452REY6TR Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32L452REY6TR is suitable for 6 applications: Industrial Sensors, Smart Meters, Wearable Devices, Medical Monitoring, IoT Edge Nodes, Portable Test Equipment.

🏭

Industrial Sensors

The STM32L452REY6TR is ideal for industrial sensors due to its ultra-low-power modes, wide operating voltage, and multiple communication interfaces. It can process sensor data locally, reducing the need for continuous wireless transmission. In a typical industrial sensor node, the MCU reads analog signals via the 12-bit ADC, applies digital filtering, and transmits results over RS-485 or CAN. The low-power Stop 2 mode (28 Β΅A) allows battery-powered operation for years. The 80 MHz Cortex-M4 core with FPU handles complex algorithms like vibration analysis or predictive maintenance. The wide temperature range (-40Β°C to +85Β°C) ensures reliable operation in harsh environments. Compared to higher-power MCUs, the STM32L452REY6TR extends battery life by 3-5x while maintaining sufficient processing capability.

⚑

Smart Meters

Smart meters require precise measurement, low power, and secure communication. The STM32L452REY6TR provides a 12-bit ADC for accurate energy monitoring, a TRNG for security, and multiple UARTs for communication with PLC or RF modules. Its low-power modes enable battery backup operation during power outages. The 512 KB Flash allows storing tariff tables and usage history. The Cortex-M4 FPU accelerates calculation of RMS voltage and current. In a typical smart meter, the MCU samples voltage and current at 1 kHz, computes power, and communicates via a UART to a PLC modem. The Stop 2 mode (28 Β΅A) preserves data during standby. The wide voltage range (1.71V-3.6V) supports operation from a backup battery. Compared to 8-bit MCUs, the STM32L452REY6TR offers 10x more processing power and advanced security features.

πŸ“±

Wearable Devices

Wearable devices demand ultra-low power and small form factor. The STM32L452REY6TR's UFBGA-64 package (4x4 mm) fits compact PCBs, while its low-power modes extend battery life. The 80 MHz core handles sensor fusion algorithms for activity tracking. The integrated USB 2.0 FS enables charging and data transfer. In a typical fitness tracker, the MCU reads an accelerometer via I2C, processes steps, and displays data on an OLED. The Stop 2 mode (28 Β΅A) allows the device to remain in standby for days. The 160 KB SRAM buffers sensor data during active periods. The wide voltage range supports a Li-Po battery (3.7V) with a buck-boost converter. Compared to Cortex-M0+ MCUs, the Cortex-M4 with FPU provides 2x faster math processing for real-time algorithms.

πŸ’Š

Medical Monitoring

Medical devices require high reliability and low power. The STM32L452REY6TR meets these needs with its wide temperature range, low-power modes, and rich analog peripherals. It can interface with biosensors via ADC and I2C, process signals with the FPU, and communicate via BLE or USB. In a typical heart rate monitor, the MCU samples an ECG signal at 500 Hz, filters noise, and transmits data via BLE. The 12-bit ADC provides sufficient resolution for medical signals. The Stop 2 mode (28 Β΅A) enables long standby between measurements. The 512 KB Flash stores patient data and firmware updates. The Cortex-M4 FPU accelerates digital filtering algorithms. Compared to general-purpose MCUs, the STM32L452REY6TR offers lower power consumption and better analog performance, making it suitable for portable medical devices.

🧩

IoT Edge Nodes

IoT edge nodes require connectivity, processing, and low power. The STM32L452REY6TR provides multiple communication interfaces (USART, SPI, I2C, USB, CAN) and an 80 MHz core for edge computing. It can run lightweight ML models for anomaly detection. In a typical IoT node, the MCU collects sensor data, processes it locally, and sends only relevant information to the cloud via Wi-Fi or LoRa. The low-power modes allow battery-powered operation for months. The 512 KB Flash stores firmware and ML models. The TRNG enhances security for encrypted communication. The wide voltage range supports various power sources. Compared to higher-power MCUs, the STM32L452REY6TR reduces energy consumption by 50% while maintaining sufficient performance for edge AI.

πŸ”§

Portable Test Equipment

Portable test equipment requires high accuracy and low power. The STM32L452REY6TR's 12-bit ADC and DAC enable precise measurements and signal generation. The 80 MHz core handles complex algorithms for signal processing. In a typical handheld multimeter, the MCU samples voltage and current, calculates RMS, and displays results on an LCD. The low-power modes extend battery life. The 512 KB Flash stores calibration data and firmware. The USB interface allows data logging to a PC. The wide temperature range ensures accuracy in various environments. Compared to 16-bit MCUs, the Cortex-M4 with FPU provides faster floating-point math for accurate calculations. The STM32L452REY6TR is a cost-effective solution for professional test equipment.

Recommended Products Summary

LPS22HH Pressure sensor interfacing via I2C/SPI Used in: Industrial Sensors HTS221 Humidity and temperature sensor Used in: Industrial Sensors STPM32 Energy metering IC with SPI interface Used in: Smart Meters S2-LP Sub-GHz RF transceiver for wireless communication Used in: Smart Meters LSM6DSO 6-axis IMU with I2C/SPI Used in: Wearable Devices BQ25120 Battery charger with power path management Used in: Wearable Devices ADS1292R ECG front-end with SPI interface Used in: Medical Monitoring MAX30102 Pulse oximeter sensor with I2C Used in: Medical Monitoring SPIRIT1 Sub-GHz transceiver for LoRa-like communication Used in: IoT Edge Nodes X-NUCLEO-IDW01M1 Wi-Fi module with SPI interface Used in: IoT Edge Nodes ADS1115 16-bit ADC with I2C for high-resolution measurements Used in: Portable Test Equipment DAC8568 16-bit DAC with SPI for signal generation Used in: Portable Test Equipment
What is the maximum clock frequency of STM32L452REY6TR?
The STM32L452REY6TR operates at a maximum clock frequency of 80 MHz. According to the STM32L452RE datasheet, this is achieved with the ARM Cortex-M4 core with FPU, delivering 100 DMIPS performance.
How much Flash memory does STM32L452REY6TR have?
The STM32L452REY6TR has 512 KB of Flash memory. This is part of the STM32L452 series, which offers up to 512 KB Flash and 160 KB SRAM for complex applications.
What is the operating voltage range of STM32L452REY6TR?
The STM32L452REY6TR operates from 1.71V to 3.6V. This wide range allows direct battery operation and compatibility with 3.3V logic systems.
What package is STM32L452REY6TR available in?
The STM32L452REY6TR is available in a 64-pin UFBGA package (Y6 suffix). This package measures 4.0 x 4.0 mm with a 0.5 mm pitch, ideal for compact designs.
What is the current consumption in Stop 2 mode for STM32L452REY6TR?
In Stop 2 mode, the STM32L452REY6TR consumes approximately 28 Β΅A. This low-power mode retains SRAM and register contents, enabling battery-powered applications to achieve long standby times.
Does STM32L452REY6TR support USB?
Yes, the STM32L452REY6TR includes a USB 2.0 Full-Speed (FS) interface. This allows direct connection to USB hosts for data transfer and device charging.
What is the difference between STM32L452REY6TR and STM32L452RET6?
The STM32L452REY6TR uses a UFBGA-64 package, while the STM32L452RET6 uses an LQFP-64 package. Both have the same core, memory, and peripherals, but the UFBGA package is smaller and requires different PCB layout.
Can STM32L452REY6TR be used for battery-powered IoT devices?
Yes, the STM32L452REY6TR is ideal for battery-powered IoT devices due to its ultra-low-power modes, wide voltage range, and integrated communication interfaces. Its 28 Β΅A Stop 2 current and 80 MHz performance make it suitable for edge processing.
What is the best drop-in replacement for STM32L452REY6TR?
The best drop-in replacement for STM32L452REY6TR is the STM32L452REY6 (non-tape-and-reel variant) or the STM32L452RET6 (LQFP-64 package). For cross-brand, the NXP LPC54xxx series may offer similar performance but requires pin compatibility verification.
Where can I download the STM32L452REY6TR datasheet PDF?
The STM32L452REY6TR datasheet PDF can be downloaded from the STMicroelectronics website at https://www.st.com/resource/en/datasheet/stm32l452re.pdf. This document contains full specifications, pinout, and application notes.
What is the price of STM32L452REY6TR?
As of 2026-08-09, the price of STM32L452REY6TR is approximately $6.50 for single-unit quantities, decreasing to $4.16 at 1000 units. Prices vary by distributor and availability.
Is STM32L452REY6TR in stock at major distributors?
Stock availability for STM32L452REY6TR varies by distributor. As of 2026-08-09, it is listed on DigiKey and Mouser, but stock levels fluctuate. Check the distributor websites for real-time availability.
What is the lead time for STM32L452REY6TR?
The typical lead time for STM32L452REY6TR is 8-12 weeks from STMicroelectronics, depending on order volume and market conditions. Distributors may have limited stock for immediate shipment.
Is STM32L452REY6TR suitable for industrial control applications?
Yes, the STM32L452REY6TR is suitable for industrial control due to its wide temperature range (-40Β°C to +85Β°C), robust communication interfaces (CAN, USART, SPI), and 80 MHz performance. It can handle real-time control loops and sensor interfacing.
What development tools are compatible with STM32L452REY6TR?
The STM32L452REY6TR is supported by STM32CubeIDE, Keil MDK, IAR EWARM, and GCC-based toolchains. ST also provides the STM32CubeL4 firmware package with HAL drivers and examples.
What are the key specifications of STM32L452REY6TR that engineers should know?
The STM32L452REY6TR features an 80 MHz ARM Cortex-M4 core with FPU, 512 KB Flash, 160 KB SRAM, 1.71V-3.6V operation, 28 Β΅A Stop 2 current, and a UFBGA-64 package. It includes USB 2.0 FS, CAN, multiple USART/SPI/I2C, 12-bit ADC/DAC, and 12 DMA channels.
Hey Google, what can replace STM32L452REY6TR?
The STM32L452REY6TR can be replaced by the STM32L452REY6 (same package, non-tape-and-reel) or the STM32L452RET6 (LQFP-64 package). For cross-brand, consider the NXP LPC54xxx series, but verify pin compatibility.
Is STM32L452REY6TR the same as STM32L452RET6?
No, the STM32L452REY6TR and STM32L452RET6 are not the same. The 'Y6' suffix indicates a UFBGA-64 package, while 'T6' indicates an LQFP-64 package. They have identical internal resources but different physical footprints.
What is the best NXP equivalent for STM32L452REY6TR?
A potential NXP equivalent is the LPC54S64JBD100, but it has a different package (LQFP-100) and is not pin-compatible. For a drop-in replacement, stick with STM32L452 series variants.

Engineering reference data for STM32L452REY6TR β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32L452REY6TR when you need a compact, ultra-low-power MCU with high performance and rich peripherals. It is ideal for battery-powered IoT devices, wearables, and industrial sensors where space and power are critical. If you require a larger package for easier prototyping, the STM32L452RET6 (LQFP-64) is a functional alternative but requires PCB rework. For cost-sensitive applications with lower memory needs, the STM32L452RCT6 offers reduced Flash and SRAM at a lower price. For industrial temperature ranges (-40Β°C to +125Β°C), the STM32L452REI6 is a drop-in replacement with the same UFBGA-64 package. All alternatives share the same core and peripherals, ensuring software compatibility.

Comparison with Alternatives

Parameter This Product STM32L452REY6 STM32L452RET6 STM32L452RCT6 STM32L452REI6
Package UFBGA-64 (Y6) UFBGA-64 (Y6) - same LQFP-64 (T6) - different LQFP-64 (T6) - different UFBGA-64 (I6) - same
Brand STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics
Core ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU
Maximum Frequency 80 MHz 80 MHz 80 MHz 80 MHz 80 MHz
Flash Memory 512 KB 512 KB 512 KB 256 KB 512 KB
SRAM 160 KB 160 KB 160 KB 64 KB 160 KB
Operating Temperature -40C to +85C -40C to +85C -40C to +85C -40C to +85C -40C to +125C
Price (1000 pcs) $4.16 $4.16 $4.20 $3.50 $4.50

Key Differentiators

  • Ultra-low-power Stop 2 mode with 28 Β΅A current (vs STM32L452RET6)
  • UFBGA-64 package for compact designs (vs STM32L452RET6)
  • 512 KB Flash and 160 KB SRAM (vs STM32L452RCT6)

Design Notes

Decouple each VDD pin with a 100 nF ceramic capacitor placed as close as possible to the pin. Additionally, place a 4.7 Β΅F capacitor on the main VDD rail. For VDDA, use a 1 Β΅F capacitor and a ferrite bead to isolate analog noise. Ensure VREF+ is connected to VDDA through a low-pass filter for accurate ADC readings.

For the UFBGA-64 package, use a 4-layer PCB with a solid ground plane. Route high-speed signals (USB, SPI) with controlled impedance (90 ohms for USB). Keep crystal oscillator traces short and shielded. Follow ST's layout guidelines in AN4666 for optimal EMC performance.

Do not leave unused GPIO pins floating; configure them as analog inputs or outputs to reduce leakage. Ensure the NRST pin has a 100 nF capacitor to ground for reliable reset. When using low-power modes, disable unused peripherals and clocks to achieve the specified 28 Β΅A Stop 2 current.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliant per STMicroelectronics product page. Not AEC-Q100 qualified; for automotive, consider STM32L452REI6 (industrial grade) or other automotive-grade variants.

Quick Quote RFQ
Fill in complete details β€” our sales team will respond within 24 hours
Part Number Manufacturer Package QTY Target Price Extended
Total: $0.00 USD
βœ“
Quote submitted!

We will respond to your email within 24 hours

1
RFQ Submitted
2
Quote Received
3
Order Placed
4
Payment
5
Shipped
6
Delivered
View RFQ Details