STMicroelectronics

STM32L452VCT6 - Ultra-Low-Power ARM Cortex-M4 MCU | STMicroelectronics

MPN: STM32L452VCT6 βœ“ Active
In Stock (99,999) Ships in 1-3 business days
1.71 V to 3.6 V Vdss 28 Β΅A (typ) Id LQFP-100 (14x14 mm) Package 80 MHz Speed 256 KB Memory
$8.5 USD / Unit
MOQ: 1 |
Volume Pricing
Qty Unit Price Extended
1 $8.5 $8.50
10 $7.65 $76.50
100 $6.8 $680.00
500 $6.12 $3,060.00
1,000 $5.44 $5,440.00
ℹ️ All prices are in USD

Drop-in alternatives for STM32L452VCT6 β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

STM32L452VET6

βœ… Drop-In
πŸ“¦ LQFP-100
Same pinout, 512 KB Flash instead of 256 KB

πŸ“‹ Reference alternative (not in catalog)

STM32L462VCT6

βœ… Drop-In
πŸ“¦ LQFP-100
Adds AES hardware encryption, same pinout

πŸ“‹ Reference alternative (not in catalog)

STM32L476VGT6

⚑ Same Package
πŸ“¦ LQFP-100
Different pinout, 1 MB Flash, more peripherals

πŸ“‹ Reference alternative (not in catalog)

LPC54S60JBD100

⚑ Same Package
πŸ“¦ LQFP-100
Cortex-M4F, different pinout, 256 KB Flash

πŸ“‹ Reference alternative (not in catalog)

R7FA4M1AB3CFM#AA0

⚑ Same Package
πŸ“¦ LQFP-100
Cortex-M4, different pinout, 256 KB Flash

πŸ“‹ Reference alternative (not in catalog)

ℹ️ 1 cross-package part(s) hidden β€” different package requires PCB rework and is not a true drop-in replacement. Contact us if you need cross-package suggestions.

STM32L452VCT6 Maximum Ratings & Electrical Characteristics

Core ARM Cortex-M4 with FPU
Max Frequency 80 MHz
Flash Memory 256 KB
SRAM 160 KB
Operating Voltage 1.71 V to 3.6 V
GPIO Pins 51
ADC 12-bit, 5 Msps, 16 channels
DAC 2 x 12-bit
Communication Interfaces I2C, SPI, USART, UART, LPUART, SAI, CAN, USB 2.0 FS
Package LQFP-100 (14x14 mm)
Operating Temperature -40C to +85C
Supply Current (Stop 2) 28 Β΅A (typ)
Supply Current (Run) 84 Β΅A/MHz (typ)
RTC Yes, with calendar and alarm
LCD Driver 8x40 segments
RoHS Status Compliant

STM32L452VCT6 Pin Configuration

QFP-100 Package Pinout Diagram QFP-100 14x14mm, P0.5mm, JEDEC MS-026. 1 25 QFP-100
Pin 1 PE2 β€” GPIO or alternate function
Pin 2 PE3 β€” GPIO or alternate function
Pin 3 PE4 β€” GPIO or alternate function
Pin 4 PE5 β€” GPIO or alternate function
Pin 5 PE6 β€” GPIO or alternate function
Pin 6 VBAT β€” Backup battery supply
Pin 7 PC13 β€” GPIO or RTC output
Pin 8 PC14 β€” GPIO or OSC32_IN
Pin 9 PC15 β€” GPIO or OSC32_OUT
Pin 10 PF0 β€” GPIO or OSC_IN
Pin 11 PF1 β€” GPIO or OSC_OUT
Pin 12 NRST β€” Reset (active low)
Pin 13 PC0 β€” GPIO or ADC input
Pin 14 PC1 β€” GPIO or ADC input
Pin 15 PC2 β€” GPIO or ADC input
Pin 16 PC3 β€” GPIO or ADC input
Pin 17 VDD β€” Digital power supply
Pin 18 VSS β€” Ground
Pin 19 PC4 β€” GPIO or ADC input
Pin 20 PC5 β€” GPIO or ADC input

Safe Operating Area (SOA) & Thermal Characteristics

Safe Operating Area Chart Default safe operating area chart for STM32L452VCT6 Drain-to-Source Voltage (Vds) Drain Current (Id)

No official SOA curve available for this digital IC. Always operate within absolute maximum ratings specified in the datasheet. Ensure adequate cooling and derate as needed.

Typical Applications

STM32L452VCT6 is suitable for 6 applications: Industrial Sensors, Smart Meters, Healthcare Devices, Wearable Fitness Trackers, IoT Edge Nodes, Portable Test and Measurement.

🏭

Industrial Sensors

The STM32L452VCT6 is ideal for industrial sensors that require low power consumption and high accuracy. Its 12-bit ADC with 5 Msps sampling rate enables precise measurement of analog signals from temperature, pressure, and flow sensors. The multiple low-power modes allow the device to sleep between measurements, extending battery life in wireless sensor nodes. The rich communication interfaces (I2C, SPI, UART) facilitate connection to external transceivers for data transmission. The Cortex-M4 with FPU accelerates signal processing algorithms, such as digital filtering and calibration. The wide operating voltage range (1.71V-3.6V) accommodates various power sources, including energy harvesting. The device's robust design and industrial temperature range (-40C to +85C) ensure reliable operation in harsh environments. The integrated DMA controller offloads the CPU during data transfers, improving overall system efficiency. The STM32L452VCT6 also supports firmware updates over the air, enabling remote maintenance of deployed sensors. Its small footprint and low BOM cost make it a cost-effective choice for high-volume industrial applications.

⚑

Smart Meters

The STM32L452VCT6 is well-suited for smart metering applications, such as electricity, water, and gas meters. Its ultra-low-power modes enable long battery life, often exceeding 10 years in typical metering applications. The integrated LCD driver supports direct connection to segment LCDs for displaying consumption data, eliminating the need for an external display driver. The 12-bit ADC and analog comparators are used for accurate measurement of voltage and current in electricity meters. The device's communication interfaces, including UART and LPUART, allow connection to PLC modems or RF transceivers for remote data collection. The RTC with calendar and alarm functions provides accurate time-stamping of meter readings. The STM32L452VCT6's security features, such as read-out protection and a unique ID, help prevent tampering and unauthorized access. The wide operating voltage range and low power consumption make it compatible with battery-backed power supplies. The device's high integration reduces the overall component count, lowering manufacturing costs. The Cortex-M4 core with FPU enables efficient implementation of metering algorithms, such as energy calculation and power quality analysis. The STM32L452VCT6 also supports firmware updates via the communication interface, allowing remote upgrades of metering software.

πŸ’Š

Healthcare Devices

The STM32L452VCT6 is an excellent choice for healthcare devices such as portable patient monitors, glucose meters, and pulse oximeters. Its ultra-low-power operation extends battery life, which is critical for wearable and portable medical devices. The integrated operational amplifiers and comparators can be used for signal conditioning of biosignals, such as ECG and EEG. The 12-bit ADC with high sampling rate captures physiological signals with sufficient resolution. The device's multiple communication interfaces enable data transfer to smartphones or cloud platforms via Bluetooth or Wi-Fi modules. The Cortex-M4 with FPU and DSP instructions supports real-time signal processing, such as heart rate variability analysis. The device's security features, including a true random number generator and memory protection unit, help protect patient data. The wide operating voltage range allows direct battery operation from a single lithium cell. The STM32L452VCT6's small package and low power consumption make it suitable for compact, wearable designs. The device also supports firmware updates, enabling feature enhancements and bug fixes in the field. The integrated LCD driver can be used to display vital signs on a small segment LCD, reducing component count.

πŸ“±

Wearable Fitness Trackers

The STM32L452VCT6 is ideal for wearable fitness trackers that require long battery life and small form factor. Its ultra-low-power modes, including Stop 2 with 28 Β΅A current consumption, allow the device to operate for weeks on a small battery. The integrated sensors, such as accelerometers and gyroscopes, can be connected via I2C or SPI. The Cortex-M4 with FPU enables efficient processing of sensor data for activity recognition and step counting. The device's multiple timers can be used to generate precise timing for sampling and event detection. The integrated LCD driver can drive a small segment display for showing time and activity stats. The USB 2.0 interface allows for charging and data transfer to a host computer. The device's small LQFP-100 package and low power consumption make it suitable for compact wearable designs. The STM32L452VCT6 also supports Bluetooth Low Energy via an external module, enabling wireless synchronization with smartphones. The device's security features, such as read-out protection, help protect user data. The wide operating voltage range allows direct battery operation from a coin cell or small lithium polymer battery. The device's rich peripheral set reduces the need for external components, lowering BOM cost.

🧩

IoT Edge Nodes

The STM32L452VCT6 is a powerful choice for IoT edge nodes that require local processing and low power consumption. Its Cortex-M4 core with FPU and DSP instructions enables on-device machine learning and signal processing, reducing the need to send raw data to the cloud. The device's multiple low-power modes allow it to sleep between sensor readings, conserving battery power. The rich communication interfaces, including Wi-Fi and LoRa modules, enable reliable connectivity to the cloud. The integrated ADC and DAC allow direct interfacing with analog sensors and actuators. The device's security features, such as a true random number generator and memory protection unit, help secure data transmission. The STM32L452VCT6's wide operating voltage range and low power consumption make it suitable for battery-powered or energy-harvesting IoT devices. The device's small package and high integration reduce the overall system size and cost. The STM32L452VCT6 also supports over-the-air firmware updates, enabling remote maintenance and feature updates. The device's rich peripheral set, including timers, UART, SPI, and I2C, simplifies interfacing with various sensors and actuators. The Cortex-M4 with FPU accelerates edge computing tasks, such as anomaly detection and data fusion.

πŸ”§

Portable Test and Measurement

The STM32L452VCT6 is well-suited for portable test and measurement instruments, such as handheld multimeters, oscilloscopes, and data loggers. Its high-speed 12-bit ADC (5 Msps) enables accurate sampling of analog signals. The integrated DAC can be used for waveform generation or calibration. The device's multiple timers provide precise timing for measurement and triggering. The Cortex-M4 with FPU accelerates signal processing algorithms, such as FFT and digital filtering. The device's low power consumption extends battery life in portable instruments. The rich communication interfaces, including USB, allow data transfer to a PC for analysis. The integrated LCD driver can display measurement results on a segment LCD. The device's wide operating voltage range and industrial temperature range ensure reliable operation in various environments. The STM32L452VCT6's small package and high integration reduce the size and weight of portable instruments. The device also supports firmware updates, allowing feature enhancements in the field. The integrated operational amplifiers and comparators can be used for signal conditioning. The device's security features, such as read-out protection, help protect proprietary measurement algorithms.

Recommended Products Summary

SHT31 Temperature and humidity sensor connected via I2C Used in: Industrial Sensors BMP388 Pressure sensor connected via I2C/SPI Used in: Industrial Sensors RN2483 LoRa transceiver for wireless communication Used in: Smart Meters MCP3903 Energy metering AFE connected via SPI Used in: Smart Meters MAX30102 Pulse oximeter and heart-rate sensor connected via I2C Used in: Healthcare Devices ADS1292R ECG front-end connected via SPI Used in: Healthcare Devices LSM6DSO Accelerometer and gyroscope connected via I2C/SPI Used in: Wearable Fitness Trackers nRF52832 Bluetooth Low Energy module connected via UART Used in: Wearable Fitness Trackers ESP32-WROOM-32 Wi-Fi module connected via UART/SPI Used in: IoT Edge Nodes SX1276 LoRa transceiver connected via SPI Used in: IoT Edge Nodes AD8232 Analog front-end for ECG connected via analog input Used in: Portable Test and Measurement MCP4725 12-bit DAC for waveform generation connected via I2C Used in: Portable Test and Measurement
What is the maximum clock frequency of STM32L452VCT6?
The STM32L452VCT6 operates at a maximum clock frequency of 80 MHz. According to the STM32L452VC datasheet, the Cortex-M4 core with FPU achieves 100 DMIPS at this frequency, providing high performance for ultra-low-power applications.
How much Flash and SRAM does STM32L452VCT6 have?
The STM32L452VCT6 has 256 KB of Flash memory and 160 KB of SRAM. This generous memory configuration supports complex firmware and data buffering, making it suitable for applications like IoT edge nodes and industrial sensors.
What is the operating voltage range of STM32L452VCT6?
The STM32L452VCT6 operates from 1.71 V to 3.6 V. This wide range allows direct battery operation from a single lithium cell or two alkaline cells, simplifying power supply design in portable devices.
What low-power modes are available on STM32L452VCT6?
The STM32L452VCT6 offers multiple low-power modes: Sleep, Low-power run, Low-power sleep, Stop 0, Stop 1, Stop 2, Standby, and Shutdown. In Stop 2 mode, current consumption is as low as 28 Β΅A with SRAM retention, enabling long battery life in duty-cycled applications.
Does STM32L452VCT6 have a floating-point unit?
Yes, the STM32L452VCT6 integrates a single-precision floating-point unit (FPU) as part of the ARM Cortex-M4 core. This accelerates mathematical computations and simplifies development of algorithms requiring floating-point arithmetic.
What communication interfaces does STM32L452VCT6 support?
The STM32L452VCT6 supports I2C, SPI, USART, UART, LPUART, SAI, CAN, and USB 2.0 full-speed device/host/OTG. This rich set of interfaces enables connectivity with sensors, displays, and other peripherals in embedded systems.
What is the package type of STM32L452VCT6?
The STM32L452VCT6 comes in an LQFP-100 package with a 14x14 mm body and 0.5 mm pitch. This surface-mount package is suitable for compact PCB designs and is widely used in industrial and consumer electronics.
Is STM32L452VCT6 suitable for battery-powered applications?
Yes, the STM32L452VCT6 is designed for ultra-low-power operation, with a run current of 84 Β΅A/MHz and a Stop 2 current of 28 Β΅A. This makes it ideal for battery-powered devices such as wearables, smart meters, and IoT sensors that require long battery life.
What is the difference between STM32L452VCT6 and STM32L452RCT6?
The STM32L452VCT6 and STM32L452RCT6 differ in package and pin count: the VCT6 is LQFP-100, while the RCT6 is LQFP-64. Both have the same core, Flash, and SRAM, but the VCT6 offers more GPIOs and peripherals due to the larger package.
Can STM32L452VCT6 be used for motor control?
Yes, the STM32L452VCT6 can be used for motor control thanks to its advanced timers (TIM1 and TIM8) that generate PWM signals, and its 12-bit ADC for current sensing. The Cortex-M4 with FPU and DSP instructions enables efficient implementation of control algorithms like FOC.
What development tools are compatible with STM32L452VCT6?
The STM32L452VCT6 is supported by STM32CubeIDE, Keil MDK-ARM, IAR EWARM, and GCC-based toolchains. ST also provides the STM32CubeL4 firmware package with HAL and LL drivers, plus examples and middleware for rapid development.
Is STM32L452VCT6 RoHS compliant?
Yes, the STM32L452VCT6 is RoHS compliant, as indicated in the ST product page and datasheet. It is also free of halogens and antimony, meeting environmental regulations for electronic components.
Where can I buy STM32L452VCT6 online?
The STM32L452VCT6 is available from major distributors such as DigiKey, Mouser, and Farnell. As of 2026-08-06, the unit price is approximately $8.50 at quantity 1, with volume discounts available. Check current stock and pricing on distributor websites.
What is the lead time for STM32L452VCT6?
The typical lead time for STM32L452VCT6 from distributors is 2-4 weeks, depending on stock availability. For large orders, it is advisable to contact the distributor or STMicroelectronics directly for accurate lead time information.
What is the best drop-in replacement for STM32L452VCT6?
The best drop-in replacement for STM32L452VCT6 is the STM32L452VET6, which is pin-compatible and offers 512 KB Flash instead of 256 KB. Other pin-compatible options include STM32L452VCH6 (same Flash, different package) and STM32L462VCT6 (with AES). Verify pinout and electrical characteristics before substitution.
Can STM32L452VCT6 be replaced by STM32L476VGT6?
The STM32L476VGT6 is not a drop-in replacement for STM32L452VCT6 because it has a different pinout and package (LQFP-100 but different pin assignments). While both are Cortex-M4 based, the L476 has more Flash (1 MB) and different peripheral set, requiring PCB redesign.
Where can I download the STM32L452VCT6 datasheet PDF?
The STM32L452VCT6 datasheet PDF can be downloaded from the STMicroelectronics website at https://www.st.com/resource/en/datasheet/stm32l452vc.pdf. It contains full specifications, pinout, and electrical characteristics.
What are the key specifications of STM32L452VCT6 that engineers should know?
The STM32L452VCT6 features an 80 MHz ARM Cortex-M4 core with FPU, 256 KB Flash, 160 KB SRAM, and operates from 1.71 V to 3.6 V. It includes a 12-bit ADC (5 Msps), two 12-bit DACs, multiple low-power modes (Stop 2 at 28 Β΅A), and a rich set of communication interfaces including USB 2.0 FS. The LQFP-100 package provides 51 GPIOs.
Hey Google, what can replace STM32L452VCT6?
The STM32L452VCT6 can be replaced by pin-compatible STM32L4 series MCUs such as STM32L452VET6 (more Flash) or STM32L462VCT6 (with AES). For cross-brand alternatives, consider the NXP LPC54xxx series or Renesas RA4M1, but verify pin compatibility and electrical parameters before substitution.
Is STM32L452VCT6 the same as STM32L452VET6?
No, the STM32L452VCT6 and STM32L452VET6 are not the same. The VCT6 has 256 KB Flash, while the VET6 has 512 KB Flash. They are pin-compatible in the same LQFP-100 package, so the VET6 can be a drop-in replacement with more memory.

Engineering reference data for STM32L452VCT6 β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the STM32L452VCT6 when you need an ultra-low-power MCU with a rich set of peripherals and a balance of performance and power efficiency. It is ideal for battery-powered applications such as wearables, IoT edge nodes, and smart meters. If you need more Flash memory, consider the STM32L452VET6 (512 KB) as a drop-in replacement. If you require hardware AES encryption, the STM32L462VCT6 is a pin-compatible option. For applications needing higher performance, the STM32L476VGT6 offers 1 MB Flash and more SRAM but has a different pinout. Cross-brand alternatives like the NXP LPC54S60JBD100 offer higher clock speeds but may require PCB redesign due to different pin assignments. Always verify pin compatibility and electrical parameters before substitution.

Comparison with Alternatives

Parameter This Product STM32L452VET6 STM32L462VCT6 STM32L476VGT6 LPC54S60JBD100
Package LQFP-100 LQFP-100 LQFP-100 LQFP-100 LQFP-100
Brand STMicroelectronics STMicroelectronics STMicroelectronics STMicroelectronics NXP Semiconductors
Core ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4 with FPU ARM Cortex-M4F
Max Frequency 80 MHz 80 MHz 80 MHz 80 MHz 180 MHz
Flash Memory 256 KB 512 KB 256 KB 1 MB 256 KB
SRAM 160 KB 160 KB 160 KB 128 KB 256 KB
Operating Voltage 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V 1.71 V to 3.6 V
ADC 12-bit, 5 Msps, 16 channels 12-bit, 5 Msps, 16 channels 12-bit, 5 Msps, 16 channels 12-bit, 5 Msps, 16 channels 12-bit, 1 Msps, 16 channels
USB USB 2.0 FS USB 2.0 FS USB 2.0 FS USB 2.0 FS USB 2.0 HS

Key Differentiators

  • Ultra-low-power Stop 2 mode with 28 Β΅A current consumption (vs STM32L476VGT6)
  • Integrated LCD driver supporting up to 8x40 segments (vs LPC54S60JBD100)
  • True random number generator (TRNG) for enhanced security (vs STM32L452VET6)

Design Notes

For optimal power efficiency, use the internal LDO or connect an external SMPS step-down converter to the VDD pins. Place a 100 nF decoupling capacitor close to each VDD pin and a 4.7 Β΅F capacitor on the main VDD rail. In low-power modes, ensure that the voltage regulator is configured correctly (e.g., in Stop 2 mode, the regulator is in low-power mode).

For the LQFP-100 package, ensure proper soldering with a 0.5 mm pitch. Use a 4-layer PCB with a solid ground plane for best EMC performance. Keep analog and digital grounds separate and connect them at a single point. Place the crystal oscillator close to the OSC_IN/OSC_OUT pins and add load capacitors as specified in the datasheet.

Do not leave unused GPIO pins floating; configure them as analog inputs to minimize leakage current. Ensure the VBAT pin is connected to a backup battery or tied to VDD if not used. When using the ADC, avoid sampling during high-current switching events to reduce noise. Also, verify that the supply voltage does not exceed the absolute maximum rating of 3.6 V.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS compliant per ST product page. Not AEC-Q100 qualified; for automotive, consider STM32L452VCT6 with extended temperature range or other automotive-grade variants.

Data verified on: 2026-08-06
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