Texas Instruments

LMP7721MA/NOPB - 3fA Bias Precision Op Amp 17MHz | TI

料号: LMP7721MA/NOPB ✓ 量产中
有现货 1-3 个工作日内发货
1.8 V to 5.5 V (single); ±0.9 V to ±2.75 V (dual) Vdss 3 fA typical (±20 fA max at 25C, ±900 fA max at 85C) Id 8-SOIC (0.154 in, 3.90 mm width), isolated pinout Package
低至 $2.02 USD / 件
最小起订量: 1 |
价格更新于: 2026-08-30
批量定价
数量 单价 小计
1 $3.03 $3.03
10 $2.75 $27.50
100 $2.48 $248.00
500 $2.24 $1,120.00
1,000 $2.02 $2,020.00
ℹ️ 所有价格均以 USD 计价

LMP7721MA/NOPB 概述

The Texas Instruments LMP7721MA/NOPB is a precision operational amplifier featuring the industry's lowest specified input bias current of 3 femtoamperes (fA), with guaranteed limits of ±20 fA at 25°C and ±900 fA at 85°C. It delivers a 17 MHz gain-bandwidth product, 12.8 V/µs slew rate, and rail-to-rail output swing from a supply of 1.8V to 5.5V (or ±0.9V to ±2.75V dual) in an 8-pin SOIC (D) package.

An operational amplifier (op amp) is a high-gain voltage amplifier with differential inputs and a single-ended output, used throughout analog signal conditioning, filtering, and instrumentation systems. The LMP7721 belongs to the precision amplifier family within linear integrated circuits; its distinguishing attribute, ultra-low input bias current, enables accurate measurement of tiny currents from very high-impedance sources such as electrochemical electrodes and photodiodes, which standard CMOS or bipolar op amps cannot resolve.

Key features include 7.5 nV/√Hz input voltage noise, 84 dB open-loop gain, typical offset voltage of 26 µV, and input impedance of 10^13 Ω. A shutdown mode reduces supply current to 40 µA, supporting battery-operated designs. The device is specified over the extended industrial temperature range of -40°C to +125°C.

Technically, the LMP7721 employs a CMOS input stage with bias-current cancellation to reach femtoampere input currents. Critically, its unique SOIC-8 pinout physically isolates the input pins (2 and 3) from the output (pin 6) and supply pins (4 and 7), preventing PCB leakage currents from corrupting the femtoampere-level input and enabling effective guard-ring routing.

Typical applications include electrochemical sensors (pH, gas, and ion-selective electrodes), photodiode/transimpedance amplifiers, high-impedance buffers, and medical instrumentation such as glucose monitors and blood gas analyzers, where picoampere-level accuracy is mandatory.

When designing with this device, implement guard rings around the input pins and clean, no-clean-free flux PCB practices to fully realize the 3 fA performance; otherwise board leakage, not the amplifier, will dominate input current error.

直接替换替代料: LMP7721MA/NOPB ——相同封装,引脚兼容。需要 PCB 改动的不同封装料号已排除。

本系列中的变体

可与以下型号直接替换的同系列型号: LMP7721MA/NOPB (相同外形与封装尺寸) ——差异在于 Amplifier Type, Package, RoHS Status, Supply Voltage Range.

Texas Instruments
Amplifier Type: Precision, General Purpose
Package: 8-SOIC (3.90 mm width)
RoHS Status: Compliant (NOPB = no lead, RoHS)

快速对比工具——选择替代料号进行并排对比:

LMP7721MA/NOPB

✅ 直接替换
Texas Instruments
📦 8-SOIC (D, isolated pinout)
Precision, General Purpose · 1 · 3 fA · ±20 fA · ±900 fA · 17 MHz · 12.8 V/us · 1.8 V to 5.5 V

✓ 有现货

联系询价

查看数据手册 →

LMP7721MAX/NOPB

✅ 直接替换
📦 8-SOIC (D, isolated pinout)
same die, tape-and-reel packaging (MA/NOPB ships in tube)

📋 参考替代料(不在目录中)

OPA380AID

⚡ 相同封装
Texas Instruments
📦 8-SOIC
Transimpedance Amplifier (TIA) · 1 · 90 MHz · > 1 MHz · 50 pA (max) · 25 uV (max) · 0.1 uV/C (max) · up to 1 mA

✓ 有现货

$1.85 / 个

查看数据手册 →

LMP8350MA/NOPB-Q1

⚡ 相同封装
Texas Instruments
📦 8-SOIC
ADC Driver IC (fully-differential amplifier) · Data Acquisition · 8-SOIC (0.154 in, 3.90 mm Width) · -40C to +85C · Fully-Differential, Ultra-Low Distortion · 3 selectable modes via mode enable pin (PowerWise) · LMP precision amplifier family · Surface Mount

✓ 有现货

$2.53 / 个

查看数据手册 →

LMC6001AIN

⚡ 相同封装 ⚠️ 规格未核验
📦 8-SOIC
ultra-low 25 fA bias CMOS op amp, standard pinout, only 1.3 MHz GBW

📋 参考替代料(不在目录中)

AD549LH

⚡ 相同封装 ⚠️ 规格未核验
📦 8-SOIC
cross-brand electrometer-grade op amp, ~60 fA bias class, standard pinout

📋 参考替代料(不在目录中)

LMP7721MA/NOPB 最大额定值与电气特性

Input Bias Current 3 fA typical (±20 fA max at 25C, ±900 fA max at 85C)
Gain Bandwidth Product 17 MHz
Slew Rate 12.8 V/us
Supply Voltage Range 1.8 V to 5.5 V (single); ±0.9 V to ±2.75 V (dual)
输出类型 Rail-to-Rail
Input Voltage Noise 7.5 nV/√Hz
Open-Loop Gain 84 dB
Offset Voltage 26 uV typical
Input Impedance 10^13 ohm
Number of Circuits 1
Quiescent Current (shutdown) 40 uA
工作温度 -40C to +125C
封装 8-SOIC (0.154 in, 3.90 mm width), isolated pinout
安装类型 Surface Mount
Amplifier Type General Purpose / Precision
RoHS 状态 Compliant (NOPB = lead-free)

LMP7721MA/NOPB 引脚配置

SOIC-8 Package Pinout Diagram SOIC-8 8-pin small outline IC, 3.9x4.9mm, P1.27mm, JEDEC MS-012. 1 8 2 7 3 6 4 5 SOIC-8
引脚 1 OUT — Amplifier output (moved to pin 1 in isolated pinout)
引脚 2 IN+ — Non-inverting input (guarded / isolated)
引脚 3 IN- — Inverting input (guarded / isolated)
引脚 4 V- — Negative supply
引脚 5 SD — Shutdown control
引脚 6 NC — No connect (isolation spacing)
引脚 7 V+ — Positive supply
引脚 8 NC — No connect (isolation spacing)

典型应用

LMP7721MA/NOPB 适用于 6 应用s: Electrochemical Sensor Front End, Photodiode / Transimpedance Amplifier, Medical Instrumentation, High-Impedance Buffer, Battery-Powered Portable Instruments, Test and Measurement / Picoammeter Front Ends.

🧩

Electrochemical Sensor Front End

The LMP7721's 3 fA input bias current and 10^13 ohm input impedance make it the definitive buffer for pH, dissolved-oxygen, gas, and ion-selective electrodes, which present gigaohm source impedances. Even picoampere-level bias from ordinary CMOS op amps polarizes electrodes and corrupts readings; the LMP7721 keeps this error orders of magnitude below sensor resolution. Placed directly at the electrode as a unity-gain buffer, its rail-to-rail output swings within millivolts of the 1.8V to 5.5V rail, and its isolated SOIC-8 pinout permits guard rings that suppress board leakage.

🎥

Photodiode / Transimpedance Amplifier

In picoammeter-grade photodiode receivers, the transimpedance amplifier's input bias current sets the dark-current noise floor. The LMP7721's 3 fA bias and 17 MHz GBW allow megohm feedback resistors with usable bandwidth, enabling optical power detection down to the femtoampere range in optical power meters, fluorescence detectors, and smoke detectors. The 7.5 nV/√Hz voltage noise supports stable operation with large feedback resistances, while the isolated input pinout permits effective guard rings that keep PCB leakage from masking the photodiode signal.

💊

Medical Instrumentation

Glucose monitors, blood gas analyzers, and biochemical sensors rely on measuring nanoampere-to-femtoampere electrochemical currents. The LMP7721's ±20 fA guaranteed limit at 25°C delivers the accuracy these diagnostic front ends demand, while its 1.8V operation suits battery-powered portable medical devices. Low offset voltage of 26 µV preserves resolution at small electrode potentials, and the shutdown mode (40 µA quiescent) extends battery life between charges in wearable and handheld medical instruments.

🔧

High-Impedance Buffer

Piezoelectric, capacitive, and Pyroelectric sensors require buffers with input bias currents far below the signal current. The LMP7721's 10^13 ohm input impedance and 3 fA bias preserve charge integrity when buffering these sources, and its 17 MHz GBW and 12.8 V/µs slew rate handle fast transient events without slew-induced distortion. The rail-to-rail output maximizes dynamic range on low single-supply rails, and the isolated SOIC-8 pinout enables leakage-controlled layout directly at the sensor connector.

📱

Battery-Powered Portable Instruments

Handheld pH meters, environmental gas detectors, and water-quality testers benefit from the LMP7721's wide 1.8V to 5.5V supply range, allowing direct operation from two alkaline cells or one Li-ion cell without a boost converter. The shutdown feature reduces supply current to 40 µA between measurements, and the extended -40°C to +125°C range supports outdoor field instruments. Combined with a low-power MCU, the complete analog front end can operate for months on primary cells.

🖥️

Test and Measurement / Picoammeter Front Ends

Bench picoammeters, electrometers, and semiconductor parametric analyzers demand femtoampere-class input stages. The LMP7721's ±20 fA specified limit makes it suitable as the input electrometer amplifier in such instruments, with 84 dB open-loop gain ensuring linearity in high-gain shunt configurations. Its isolated pinout plus guard-ring layout suppresses leakage that would otherwise dominate femtoampere measurements, and the 17 MHz GBW supports fast current-range switching without long settling tails.

What is the input bias current of LMP7721MA/NOPB?
The LMP7721MA/NOPB has the industry's lowest specified input bias current of 3 fA typical, with guaranteed maximum limits of ±20 fA at 25°C and ±900 fA at 85°C. According to the TI datasheet, this is achieved through patented input bias current cancellation circuitry in the CMOS input stage.
Where to download LMP7721MA/NOPB datasheet PDF?
The official LMP7721 datasheet PDF (35 pages, covering the LMP7721MA/NOPB) is available for free download from Texas Instruments at https://www.ti.com/lit/ds/symlink/lmp7721.pdf. It includes complete specifications, application circuits for electrochemical and photodiode amplifiers, and guard-ring layout recommendations.
What is the price of LMP7721MA/NOPB?
The LMP7721MA/NOPB prices start around $3.03 at single-unit quantity as of 2026-08-30, dropping to roughly $2.02 at 1000 pieces per LCSC and Octopart distributor data. Compare bulk discounts across DigiKey, Mouser, and LCSC before ordering, as stock and pricing fluctuate.
Is LMP7721MA/NOPB in stock?
Yes, the LMP7721MA/NOPB is in stock and ships today from major distributors including DigiKey and LCSC as of 2026-08-30. TI lists the part as active, so production supply is ongoing; verify real-time availability on distributor pages before placing volume orders.
What is the best drop-in replacement for LMP7721MA/NOPB?
The best drop-in replacements are the LMP7721MA/NOPB-Q1 (automotive AEC-Q100 variant, same die and pinout) and LMP7721MAX/NOPB (same die in tape-and-reel packaging). Both are pin-compatible in the same SOIC-8 isolated pinout. Note that standard-pinout SOIC-8 op amps are NOT drop-in compatible because the LMP7721 uses a unique input-isolated pinout.
Can AD8628 replace LMP7721MA/NOPB?
No, the AD8628 from Analog Devices cannot directly replace the LMP7721MA/NOPB. Although AD8628 offers low bias current (10 pA max) and auto-zero offset performance, it is not pin-compatible with the LMP7721's unique input-isolated SOIC-8 pinout, and its 10 pA bias current is over 3000x higher than the LMP7721's 3 fA, making it unsuitable for femtoampere electrochemical measurements.
LMP7721 vs LMC6001 - which is better for picoammeter circuits?
The LMP7721 is better for picoammeter circuits. Its 3 fA typical input bias current with a ±20 fA guaranteed limit at 25°C far exceeds the LMC6001's 25 fA typical / 10 pA max specification. The LMP7721 also adds 17 MHz GBW versus the LMC6001's 1.3 MHz and a leakage-isolated pinout, though it draws more quiescent current.
LMP7721 vs OPA380 - when should I choose LMP7721?
Choose the LMP7721 when ultra-low input bias current is the priority, such as pH probes, ion-selective electrodes, or picoampere photodiode sensing: 3 fA versus the OPA380's picoampere-level bias. Choose the OPA380 when you need a faster, internally compensated transimpedance amplifier with 80 MHz bandwidth for high-speed photodiode applications. They are not pin-compatible; the OPA380 uses a standard SOIC-8 pinout.
Is LMP7721MA/NOPB suitable for pH meter and electrochemical sensor front ends?
Yes, the LMP7721MA/NOPB is ideal for pH meters and electrochemical sensor front ends. pH electrodes and ion-selective electrodes present gigaohm source impedances where even picoampere bias current causes measurement error; the LMP7721's 3 fA bias, 10^13 ohm input impedance, and 1.8V to 5.5V operation keep electrode error below measurable limits.
Why does the LMP7721 use a special SOIC-8 pinout?
The LMP7721's SOIC-8 pinout physically isolates the input pins (2 and 3) from the output (pin 6) and supply pins (4 and 7). According to the TI datasheet, this unique arrangement prevents PCB surface leakage current from reaching the input pins and enables effective guard-ring routing, which is essential because board leakage typically exceeds the amplifier's 3 fA input bias current.
How should I lay out the PCB to achieve 3 fA performance with LMP7721?
Implement guard rings driven at the input potential around pins 2 and 3, keep input traces short and suspended over grounded keep-out areas, and use low-leakage board materials with careful flux removal. Without these precautions, PCB leakage (often picoamperes), not the amplifier, will dominate the input current error.
Does LMP7721MA/NOPB have a shutdown mode for battery-powered designs?
Yes, the LMP7721 includes a shutdown mode that reduces supply current to 40 µA, making it suitable for battery-operated portable instruments such as handheld pH meters and gas detectors. The wide 1.8V to 5.5V single-supply range also allows direct operation from two alkaline cells or a single Li-ion cell.
What are the key specifications of LMP7721MA/NOPB that engineers should know?
The LMP7721MA/NOPB delivers 3 fA typical input bias current (±20 fA max at 25°C), 17 MHz gain-bandwidth product, 12.8 V/µs slew rate, 7.5 nV/√Hz noise, 84 dB open-loop gain, 26 µV offset, 10^13 ohm input impedance, and rail-to-rail output from a 1.8V to 5.5V supply in an 8-SOIC isolated-pinout package over -40°C to +125°C.
Is the LMP7721MA/NOPB RoHS compliant and lead-free?
Yes, the /NOPB suffix indicates Texas Instruments' No-Pb (lead-free) RoHS-compliant build. The device is manufactured lead-free and is suitable for RoHS-directed assemblies; verify REACH and conflict-minerals declarations on TI's product page for your compliance documentation.
What is the Texas Instruments equivalent for ultra-low bias current op amps besides LMP7721?
Within TI's portfolio, the LMC6001 (25 fA typical bias) and OPA129 (100 fA, precision picoammeter amplifier) are ultra-low-bias alternatives, and the LMP7721MA/NOPB-Q1 is the automotive-qualified version of this exact die. Cross-brand, ADI offers the AD549 (electrometer grade). None are pin-compatible with the LMP7721's isolated pinout.

工程参考数据: LMP7721MA/NOPB ——对比、设计指导和合规信息。

选型指南

Choose the LMP7721MA/NOPB when femtoampere-level input accuracy is mandatory: electrochemical electrodes, picoammeter front ends, and high-impedance photodiode sensing. Choose LMP7721MA/NOPB-Q1 for the same performance in AEC-Q100 automotive programs. Choose LMP7721MAX/NOPB only if tape-and-reel pick-and-place quantity packaging is required (same die). Choose OPA380AID when the application is a fast photodiode TIA needing 80 MHz bandwidth and picoampere bias suffices - it is not pin-compatible. Choose LMC6001AIN or AD549LH when wide supply rails (up to ±18V) are required and their picoampere-class bias is acceptable. Remember: any non-LMP7721 alternative uses a standard SOIC-8 pinout and requires PCB rework.

与替代料对比

参数 本产品 LMP7721MA/NOPB-Q1 LMP7721MAX/NOPB OPA380AID LMC6001AIN AD549LH
Package 8-SOIC (isolated pinout) 8-SOIC (isolated pinout) - same 8-SOIC (isolated pinout) - same 8-SOIC (standard pinout) 8-SOIC (standard pinout) 8-SOIC (standard pinout)
Brand Texas Instruments Texas Instruments Texas Instruments Texas Instruments Texas Instruments Analog Devices
Input Bias Current 3 fA typ (±20 fA max 25C) 3 fA typ (same die) 3 fA typ (same die) pA class 25 fA typ / 10 pA max ~60 fA typ
Gain Bandwidth Product 17 MHz 17 MHz 17 MHz 80 MHz (TIA config) 1.3 MHz 1 MHz
Supply Voltage Range 1.8 V to 5.5 V 1.8 V to 5.5 V 1.8 V to 5.5 V 2.7 V to 5.5 V ±2 V to ±18 V ±5 V to ±18 V
Automotive Grade No Yes (AEC-Q100) No No No No
Drop-in Compatible - Yes - pin-to-pin Yes - pin-to-pin No - standard pinout No - standard pinout No - standard pinout

关键差异点

  • Industry's lowest specified input bias current (对比 LMC6001AIN)
  • Leakage-isolated pinout enables guard rings (对比 OPA380AID)
  • Higher bandwidth than legacy electrometer op amps (对比 AD549LH)

设计说明

To realize the 3 fA input bias specification, route guard rings around input pins 2 and 3, driven by a low-impedance potential equal to the input common-mode voltage (buffer the input with a second amplifier or tie to ground for virtual-ground nodes). Suspend input traces over a ground keep-out, minimize trace length, and avoid vias on input nets. The LMP7721's isolated SOIC-8 pinout provides physical spacing between inputs and output/supply pins specifically to make this layout practical.

PCB contamination is the dominant error source in femtoampere designs: flux residue, fingerprints, and moisture create picoampere-level leakage paths that completely mask the amplifier's 3 fA bias. Use no-clean or fully washable flux with validated cleaning, conformal-coat or pot input areas where possible, and select low-leakage, C0G feedback capacitors in TIA configurations. Never use standard electrolytic or generic MLCCs in the input signal path.

Operate the LMP7721 from a clean, well-decoupled 1.8V to 5.5V rail: place 100 nF ceramic capacitors within 2 mm of pins 4 and 7 plus a 1 uF bulk capacitor nearby. In battery designs, power the amplifier from a low-noise LDO rather than directly from a switching converter to preserve the low noise floor enabled by the 7.5 nV/√Hz input stage.

In high-impedance TIA configurations, compensate the feedback network for the photodiode or electrode capacitance to avoid peaking; the 17 MHz GBW permits larger feedback resistors but increases sensitivity to stray capacitance. Keep feedback resistor leads short and elevated from the board to reduce parasitic capacitance across the resistor.

合规信息

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
无铅
Yes
无卤
Unknown
冲突矿物
Unknown

NOPB suffix denotes TI No-Pb (lead-free) RoHS-compliant construction. AEC-Q100 qualification is available via LMP7721MA/NOPB-Q1.

数据核验日期: 2026-08-30 ——数据由 XAIPART 元器件工程团队核验和整理

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LMP7721MA/NOPB datasheet LMP7721MA/NOPB price buy Texas Instruments LMP7721 3 femtoampere amplifier lowest input bias current op amp 3 fA SOIC-8 precision op amp isolated pinout LMP7721 pH meter electrochemical sensor amplifier LMP7721 vs LMC6001 picoammeter LMP7721MA/NOPB drop-in replacement LMP7721 transimpedance amplifier photodiode what is the best ultra-low bias current op amp LMP7721 pinout SOIC-8 guard ring LMP7721MA/NOPB equivalent ADI

相关元器件 & 术语

Texas Instruments LMP7721MA/NOPB LMP7721 LMP7721MA/NOPB-Q1 LMP7721MAX/NOPB LMC6001AIN OPA380AID AD549LH operational amplifier precision amplifier input bias current transimpedance amplifier SOIC-8 surface mount RoHS AEC-Q100 electrochemical sensor photodiode guard ring gain bandwidth product rail-to-rail output shutdown mode
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LMP7721MA/NOPB:3 fA 偏置精密运算放大器,17 MHz GBW — 完整工程师指南、规格、替代品与应用
TI 的 LMP7721MA/NOPB:典型输入偏置电流 3 fA,17 MHz GBW,12.8 V/µs,1.8–5.5 V 供电,SOIC-8 隔离引脚排列。截至 2026-09-04,现货起价 $2.02(1000 件)。
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