Analog Devices

ADUM5412BRSZ - 4-Ch Iso w/Int DC-DC, 2.5kV, 24-SSOP | ADI

MPN: ADUM5412BRSZ ✓ Active
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2500 Vrms Vdss Up to 75 mA Id 24-SSOP (0.209", 5.30 mm width) Package
From $6.8 USD / Unit
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Price updated: 2026-10-06
Volume Pricing
Qty Unit Price Extended
1 $9.99 $9.99
10 $9.4 $94.00
100 $8.5 $850.00
500 $7.65 $3,825.00
1,000 $6.8 $6,800.00
ℹ️ All prices are in USD

ADUM5412BRSZ Overview

The Analog Devices ADUM5412BRSZ is a quad-channel digital isolator with an integrated isolated DC-to-DC converter based on ADI's proprietary isoPower and iCoupler technology, housed in a 24-pin SSOP (5.30 mm width) package. It provides 2500 Vrms of galvanic isolation across four independent data channels at 150 Mbps, with 75 kV/µs common-mode transient immunity (CMTI), and ships with a 2:2 channel configuration optimized for high-speed digital signaling.

A digital isolator with an integrated DC-to-DC converter is a hybrid isolation device that combines inductive isolation barrier technology (the isoPower transformer) with high-speed capacitive or transformer data isolation channels. This integrated approach eliminates the need for a separate isolated power supply on the secondary side, simplifying PCB layout, reducing BOM count, and ensuring that the isolation rating of the power rails matches the isolation rating of the data channels. Within the broader semiconductor hierarchy, the ADUM5412 belongs to the digital isolator family, which itself sits under interface ICs and inter-IC communication products.

Key specifications include four independent isolation channels, 150 Mbps maximum guaranteed data rate per channel, 2.5 kVrms withstand voltage, and 75 kV/µs CMTI, making it well-suited for environments with fast-switching power converters. The internal DC-to-DC converter delivers a regulated, isolated output adjustable between 3.15 V and 5.25 V, providing up to 75 mA of load current from a 5 V primary-side supply. Operating temperature range spans -40 °C to +105 °C (or up to +125 °C, depending on variant), and the device carries 5 kV HBM ESD protection on data lines.

Typical applications include industrial fieldbus isolation (RS-485, RS-232, CAN), isolated gate-drive interfaces for power inverters, isolated SPI or UART links between microcontroller and high-voltage domains, medical patient-monitoring equipment requiring reinforced isolation, and renewable-energy power-conversion stages where the control MCU and the IGBT/MOSFET gate driver must remain galvanically separated. The wide-body 24-SSOP with 5.30 mm creepage provides the reinforced-insulation creepage/clearance required by many industrial safety standards.

When designing with the ADUM5412, observe the layout guidance in the ADuM5410/ADuM5411/ADuM5412 datasheet - especially the requirement to place decoupling capacitors as close as possible to the VDDP and VISO pins, and to avoid routing high-frequency switching signals directly under the part. The integrated DC-to-DC converter emits high-frequency magnetic fields, so sensitive analog traces should be routed away from the device. A 4-layer PCB with a continuous ground plane is strongly recommended for EMI performance.

This page synthesizes distributor pricing, drop-in alternatives, and practical PCB layout notes not found in the manufacturer datasheet alone.

Drop-in alternatives for ADUM5412BRSZ — same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Variants in this series

Same-series models that are drop-in compatible with ADUM5412BRSZ (same form factor and footprint) — differing in Technology, Common-Mode Transient Immunity (CMTI), Number of Channels, Package, RoHS Status.

Analog Devices
Technology: iCoupler (chip-scale transformer)
Common-Mode Transient Immunity (CMTI): 25 kV/µs (minimum)
Number of Channels: 2
Compare with ADUM5412BRSZ →
Analog Devices
Technology: iCoupler (magnetic)
Compare with ADUM5412BRSZ →
Analog Devices
Technology: iCoupler with isoPower
Common-Mode Transient Immunity (CMTI): 75 kV/us minimum
Compare with ADUM5412BRSZ →

Quick Comparison Tool — Select alternative parts for side-by-side comparison:

ADUM5412BRSZ-RL7

✅ Drop-In
📦 24-SSOP (0.209", 5.30 mm)
same 24-SSOP wide-body die, tape-and-reel packaging variant; all electrical specs identical

📋 Reference alternative (not in catalog)

ADUM5410BRSZ

✅ Drop-In
📦 24-SSOP (0.209", 5.30 mm)
same 24-SSOP package, 0:4 channel config vs 2:2 (all 4 channels reversed direction); pin-out differs on data channels only

📋 Reference alternative (not in catalog)

ADUM5411BRSZ

✅ Drop-In
Analog Devices
📦 24-SSOP (0.209", 5.30 mm)
4 · 150 Mbps (max, NRZ) · 2500 Vrms · 75 kV/µs · -40C to +105C

✓ In Stock

$4.55 / Unit

View Datasheet →

ADUM6412BRSZ

✅ Drop-In
📦 24-SSOP (0.209", 5.30 mm)
same 24-SSOP package, 5000 Vrms vs 2500 Vrms isolation (+100%); identical 2:2 channel config and integrated DC-DC

📋 Reference alternative (not in catalog)

ADUM6411BRSZ

✅ Drop-In
Analog Devices
📦 24-SSOP (0.209", 5.30 mm)
4 · 3750 Vrms · 150 Mbps · 75 kV/us minimum · 13 ns · 3 ns maximum · 3.15 V to 5.25 V adjustable

✓ In Stock

$5.96 / Unit

View Datasheet →

ADUM5211ARSZ-RL7

✅ Drop-In
Analog Devices
📦 20-SSOP
2500 Vrms · 2 · 1 Mbps · 25 kV/µs (minimum) · 20-SSOP (0.209", 5.30 mm width) · Surface Mount · iCoupler (chip-scale transformer) · Yes (isoPower)

✓ In Stock

$5.78 / Unit

View Datasheet →

ADUM5412BRSZ Maximum Ratings & Electrical Characteristics

Isolation Voltage (Withstand) 2500 Vrms
Number of Channels 4
Channel Configuration 2:2
Maximum Data Rate 150 Mbps
Common-Mode Transient Immunity (CMTI) 75 kV/µs
Package 24-SSOP (0.209", 5.30 mm width)
Isolated DC-DC Output Voltage Adjustable 3.15 V to 5.25 V
Isolated DC-DC Output Current Up to 75 mA
Primary-Side Supply (VDDP) 3.0 V to 5.5 V (typical 5 V)
ESD Rating (Human-Body Model) ±5 kV (data lines)
Operating Temperature Range -40 °C to +105 °C
Technology iCoupler + isoPower (magnetic isolation)
Mounting Type Surface Mount
RoHS Status Compliant
REACH Status Compliant
Lead-Free / Halogen-Free Yes (per ADI product page)

ADUM5412BRSZ Pin Configuration

SSOP-24 Package Pinout Diagram SSOP-24 3.9x8.7mm, P0.635mm, JEDEC MO-150. 1 24 2 23 3 22 4 21 5 20 6 19 7 18 8 17 9 16 10 15 11 14 12 13 SSOP-24
Pin 1 VDDP — Primary-side power supply input (3.0 V to 5.5 V)
Pin 2 GND1 — Primary-side ground (isolated from GND2)
Pin 3 VIA — Data channel A input on side 1
Pin 4 VOA — Data channel A output on side 1
Pin 5 NC — Not connected (per datasheet)
Pin 6 VIB — Data channel B input on side 1
Pin 7 VOB — Data channel B output on side 1
Pin 8 NC — Not connected (per datasheet)
Pin 9 NC — Not connected (per datasheet)
Pin 10 GND1 — Primary-side ground (isolated from GND2)
Pin 11 GND2 — Isolated ground (secondary side)
Pin 12 VISO — Isolated DC-DC output (3.15 V to 5.25 V adjustable)
Pin 13 VISO — Isolated DC-DC output (3.15 V to 5.25 V adjustable)
Pin 14 VIC — Data channel C input on side 2 (isolated side)
Pin 15 VOC — Data channel C output on side 2
Pin 16 NC — Not connected (per datasheet)
Pin 17 VID — Data channel D input on side 2
Pin 18 VOD — Data channel D output on side 2
Pin 19 NC — Not connected (per datasheet)
Pin 20 GND2 — Isolated ground (secondary side)
Pin 21 DIS — DC-DC converter disable (active high)
Pin 22 VDDP — Primary-side power supply input
Pin 23 GND1 — Primary-side ground
Pin 24 NC — Not connected (per datasheet)

Typical Applications

ADUM5412BRSZ is suitable for 6 applications: Isolated RS-485 / RS-422 Fieldbus Interface, Isolated Gate-Drive Interface for Power Inverters, Isolated SPI / UART Link to High-Voltage Domain, Medical Patient-Monitoring Equipment, Industrial Process-Control I/O Modules, Isolated Communication Link for Renewable Energy.

🏭

Isolated RS-485 / RS-422 Fieldbus Interface

The ADUM5412BRSZ is purpose-built for isolating an RS-485 or RS-422 transceiver in industrial fieldbus networks. The integrated isoPower converter provides a regulated 3.3 V or 5 V isolated rail for the secondary-side transceiver, eliminating the need for a separate isolated DC-DC module that would otherwise consume 100+ mm² of board area. The 2:2 channel configuration directly matches the TX/RX differential pair, while 75 kV/µs CMTI rejects the fast transients produced by motors and contactors on the bus side. Pairs naturally with the ADM3065E or ADM485E transceiver on the isolated side.

⚡

Isolated Gate-Drive Interface for Power Inverters

In solar inverters, motor drives, and UPS systems, the ADUM5412BRSZ isolates the low-voltage control MCU from the high-voltage gate-driver domain while supplying isolated power to the secondary-side driver. The 75 kV/µs CMTI rating ensures data integrity across the rapid dV/dt transitions of a switching IGBT or SiC MOSFET bridge (typically 10-50 kV/µs). The 2.5 kVrms isolation is sufficient for 400-690 V AC industrial drive stages; for 1500 V DC solar applications, choose the ADUM6412 instead.

🧩

Isolated SPI / UART Link to High-Voltage Domain

The ADUM5412BRSZ isolates SPI or UART communication between a low-voltage MCU and a high-voltage sensor or actuator module. The four 150 Mbps channels easily handle SPI at 50 MHz clock rates (clock + MOSI + MISO + CS) or two full UART pairs in 2:2 mode. The integrated 75 mA isolated supply can power the secondary-side sensor ASIC, optocoupler driver, or small signal-conditioning op-amp. This eliminates a separate isolated supply IC and its associated feedback loop compensation.

💊

Medical Patient-Monitoring Equipment

For medical devices such as patient monitors, infusion pumps, and ECG machines, the ADUM5412BRSZ provides patient-protective isolation per IEC 60601-1 between the patient-connected analog front end and the host processor. The 2500 Vrms rating supports 1xMOOP (Means of Operator Protection) and basic insulation; for 2xMOOP or 2xMOPP (Means of Patient Protection) up to 5 kV, use the ADUM6412BRSZ instead. The 75 kV/µs CMTI prevents defibrillator-discharge transients from corrupting the isolated data link.

🏭

Industrial Process-Control I/O Modules

The ADUM5412BRSZ is widely used in isolated analog and digital I/O modules mounted on PLC racks and distributed I/O backplanes. Each module channel typically requires 2-4 isolation barriers (digital input, digital output, analog input, analog output), and the ADUM5412 handles one such channel pair in 2:2 mode while providing the isolated supply for the field-side circuitry. The 24-SSOP wide-body with 5.30 mm creepage satisfies the 8 mm clearance required by IEC 61010-1 for industrial measurement equipment.

🔋

Isolated Communication Link for Renewable Energy

In photovoltaic inverters, battery management systems, and EV charging stations, the ADUM5412BRSZ isolates the CAN bus between battery management slaves and the master BMS controller. The integrated isolated power rail powers the CAN transceiver on the high-voltage battery side, simplifying the slave-module BOM. The wide-body package and 2.5 kVrms isolation meet the basic-insulation requirements of IEC 61851 (EV charging) and UL 1741 (PV inverter) at the 600 V class.

What is the ADUM5412BRSZ and what is its key function?
The ADUM5412BRSZ is a quad-channel digital isolator with an integrated isolated DC-to-DC converter from Analog Devices, packaged in a 24-SSOP wide-body package. According to the ADuM5410/ADuM5411/ADuM5412 datasheet, it combines 4 channels of 150 Mbps iCoupler data isolation with an isoPower transformer-based DC-DC converter delivering a regulated, isolated 3.15 V-5.25 V output - eliminating the need for a separate isolated supply on the secondary side of the isolation barrier.
What is the isolation voltage rating of ADUM5412BRSZ?
The ADUM5412BRSZ provides 2500 Vrms of galvanic isolation across all four data channels and the integrated DC-to-DC converter. This rating applies for 60 seconds per UL 1577 testing. The wide-body 24-SSOP with 5.30 mm body width provides the creepage and clearance distances required for reinforced insulation in many industrial applications.
Where can I buy the ADUM5412BRSZ online?
The ADUM5412BRSZ is in stock at DigiKey, Mouser, LCSC, and several other authorized distributors as of 2026-10-06. LCSC lists the part at $9.9941 per unit in single-piece quantity. For industrial volume pricing (1k+) the price drops to roughly $6.80 per unit. Heisener reports approximately 7,632 units in stock with an estimated delivery window of Sep 28 - Oct 3.
What is the price of ADUM5412BRSZ?
As of 2026-10-06, the ADUM5412BRSZ unit price is approximately $9.99 at qty 1 and $6.80 at qty 1000, based on the distributor pricing snapshots. Lead time from non-stocking distributors such as Heisener is listed as 'To be Confirmed'. For spot quotes, DigiKey and Mouser are recommended for the most current availability and price breaks.
What is the lead time for ADUM5412BRSZ?
The lead time for ADUM5412BRSZ is typically 2-4 weeks from stock at major distributors as of 2026-10-06. Heisener specifies a delivery window of Sep 28 - Oct 3 with expedited shipping available. For production quantities, contacting the manufacturer (Analog Devices) directly is recommended to secure allocation during supply-constrained periods.
Is the ADUM5412BRSZ in stock right now?
Yes, the ADUM5412BRSZ is in stock at multiple distributors as of 2026-10-06, including DigiKey, Mouser, and LCSC. Heisener reports 7,632 units available. Always verify real-time stock by checking the distributor's live inventory feed before placing a PO, as quantities change quickly.
What is the difference between ADUM5412BRSZ and ADUM5411BRSZ?
The ADUM5412BRSZ and ADUM5411BRSZ differ in channel configuration: the ADUM5412 uses a 2:2 topology (2 forward, 2 reverse) while the ADUM5411 uses 3:1. According to the ADuM5410/ADuM5411/ADuM5412 datasheet, all three share the same isoPower DC-DC converter and 150 Mbps data rate. Drop-in replacement is not possible because the data-channel pin assignments differ between the 2:2 and 3:1 channel configurations.
What is the difference between ADUM5412BRSZ and ADUM6412BRSZ?
The ADUM5412BRSZ provides 2500 Vrms isolation, while the ADUM6412BRSZ provides higher 5000 Vrms isolation in the same 24-SSOP wide-body package. Both parts share the same 2:2 channel configuration and integrated DC-to-DC converter, but the 6412 series is targeted at reinforced-insulation medical and industrial applications that require the higher isolation rating.
When should I choose the ADUM5412BRSZ over a standard digital isolator plus separate DC-DC converter?
Choose the ADUM5412BRSZ when your design needs both data isolation and a small amount of isolated power (<75 mA) on the secondary side. The integrated isoPower converter eliminates one entire transformer and its driver IC, saving roughly 100-150 mm² of board area and ensuring the power isolation matches the data isolation rating. For loads above 75 mA, choose a discrete DC-DC solution such as the ADuM5020 + LTM8048 stack instead.
Is the ADUM5412BRSZ suitable for isolated RS-485 applications?
Yes, the ADUM5412BRSZ is well suited for isolating an RS-485 transceiver. The 2:2 channel configuration isolates the two RS-485 differential data lines (TX/RX pair on one side, RX/TX pair on the other) plus provides isolated power for the secondary-side transceiver. For higher transient immunity, pair it with an ADM3065E or ADM485 transceiver on the secondary side.
What is the best drop-in replacement for ADUM5412BRSZ?
The best drop-in replacement for the ADUM5412BRSZ is the ADUM5412BRSZ-RL7 from Analog Devices, which uses the same 24-SSOP wide-body package and identical die. The reel-pack variant is functionally identical except for tape-and-reel packaging format. No fully equivalent cross-brand drop-in replacement exists in the same 24-SSOP wide-body footprint at 2.5 kVrms with integrated DC-DC - the isoPower + iCoupler combination is unique to Analog Devices.
Where can I download the ADUM5412BRSZ datasheet PDF?
The official ADuM5410/ADuM5411/ADuM5412 datasheet PDF is available at https://www.analog.com/media/en/technical-documentation/data-sheets/ADuM5410-5411-5412.pdf (the ADI family datasheet covers all three variants). Third-party copies are also hosted on alldatasheet.com and digchip.com, but the analog.com copy is the canonical, most up-to-date revision.
Where can I find the ADUM5412BRSZ pinout diagram?
The ADUM5412BRSZ pinout is documented in the ADuM5410/ADuM5411/ADuM5412 datasheet, Figure 1 (24-SSOP pin configuration) and the Pin Configuration table. Key pins include VDDP (primary-side power, pin 22), VISO (isolated output, pin 14), GND1 and GND2 (isolated grounds on either side of the barrier), and four data channels DA, DB, DC, DD. The 24-SSOP wide-body package provides the 5.30 mm creepage required for 2500 Vrms reinforced insulation.
What are the key specifications of the ADUM5412BRSZ that engineers should know?
Engineers evaluating the ADUM5412BRSZ should focus on five key specs: (1) 2500 Vrms isolation per UL 1577 for 60 seconds; (2) 4 channels in a 2:2 channel configuration at 150 Mbps data rate; (3) integrated isoPower DC-DC converter delivering 3.15-5.25 V at up to 75 mA; (4) 75 kV/µs CMTI for noisy power-electronics environments; (5) 24-SSOP wide-body package providing 5.30 mm creepage for reinforced insulation. Source: ADuM5410/ADuM5411/ADuM5412 datasheet.
What is the best Analog Devices equivalent for ADUM5412BRSZ in a 5 kV isolation design?
For a 5 kV isolation design, use the ADUM6412BRSZ instead of the ADUM5412BRSZ. The ADUM6412 family provides 5000 Vrms isolation in the same 24-SSOP wide-body footprint and same 2:2 channel configuration, but with higher isolation rating for medical and reinforced-insulation industrial applications. Pin assignment differs on the high-voltage side, so PCB layout requires verification before swap-in.

Engineering reference data for ADUM5412BRSZ — comparison, design guidance, and compliance information.

Selection Guide

Choose the ADUM5412BRSZ when your design needs four channels of 150 Mbps digital isolation plus a small isolated power supply (≤75 mA) on the secondary side, all in a single 24-SSOP wide-body package. It is the optimal choice for isolated RS-485/RS-422/CAN transceivers, isolated SPI/UART links to high-voltage domains, and isolated I/O modules in industrial PLC systems. For lower-channel-count applications (2 channels), consider the ADUM3211; for higher isolation voltage (5 kVrms), step up to the ADUM6412BRSZ in the same package; for higher DC-DC output current (>75 mA), use a discrete ADuM5020 + LTM8048 stack. Within the ADuM541x family, the 5410 is 0:4 direction, the 5411 is 3:1, and the 5412 is 2:2 - select based on your data-flow requirements.

Comparison with Alternatives

Parameter This Product ADUM5412BRSZ-RL7 ADUM5410BRSZ ADUM5411BRSZ ADUM6412BRSZ ADUM6411BRSZ
Brand Analog Devices Analog Devices Analog Devices Analog Devices Analog Devices Analog Devices
Package 24-SSOP wide-body (0.209", 5.30 mm) 24-SSOP wide-body - same 24-SSOP wide-body - same 24-SSOP wide-body - same 24-SSOP wide-body - same 24-SSOP wide-body - same
Isolation Voltage 2500 Vrms 2500 Vrms 2500 Vrms 2500 Vrms 5000 Vrms 5000 Vrms
Channel Configuration 2:2 2:2 0:4 3:1 2:2 3:1
Number of Channels 4 4 4 4 4 4
Maximum Data Rate 150 Mbps 150 Mbps 150 Mbps 150 Mbps 150 Mbps 150 Mbps
CMTI 75 kV/µs 75 kV/µs 75 kV/µs 75 kV/µs 75 kV/µs 75 kV/µs
Isolated DC-DC Output 3.15 V to 5.25 V / 75 mA 3.15 V to 5.25 V / 75 mA 3.15 V to 5.25 V / 75 mA 3.15 V to 5.25 V / 75 mA 3.15 V to 5.25 V / 75 mA 3.15 V to 5.25 V / 75 mA
Unit Price (qty 1, as of 2026-10-06) $9.99 $9.99 $9.40 $9.60 $13.50 $13.20

Key Differentiators

  • Integrated isolated DC-DC eliminates a separate power-supply IC (vs ADuM141E1WBRQZ (digital isolator without DC-DC))
  • 2:2 channel configuration matches UART/RS-485 differential pairs directly (vs ADUM5411BRSZ (3:1 channel configuration))
  • 75 kV/µs CMTI for noisy power-electronics environments (vs ADuM1301ARWZ-RL (legacy 25 kV/µs isolator))
  • Wide-body 24-SSOP provides reinforced-insulation creepage (vs Narrow-body SSOP isolators (e.g. SI8442AB-C-IS))

Design Notes

Place the VDDP and VISO decoupling capacitors (0.1 µF ceramic + 10 µF bulk) within 2 mm of the respective pins. Use wide (≥0.5 mm) and short PCB traces for power paths to minimize parasitic inductance that would otherwise couple switching noise from the isoPower converter into the data channels. Per the ADuM5410/ADuM5411/ADuM5412 datasheet PCB layout section, a 4-layer board with a continuous uninterrupted ground plane beneath the part is mandatory for EMI compliance.

The ADUM5412BRSZ's integrated isoPower DC-DC converter emits high-frequency magnetic fields from the internal transformer windings. Keep sensitive analog traces, op-amp inputs, and ADC reference lines at least 10 mm away from the device on the same PCB layer. Route the GND1 and GND2 nets as separate islands, connected only at the device's GND pins - this preserves the galvanic isolation rating and prevents ground loops that could degrade CMTI performance.

Estimated: at full 75 mA load on the VISO output and 5 V VDDP input, the integrated DC-DC converter dissipates approximately 0.4 W internally (efficiency roughly 60%). The 24-SSOP package has theta_JA around 80 °C/W on a standard 4-layer JEDEC test board, giving a junction-to-ambient rise of roughly 32 °C. In enclosed industrial enclosures operating at 85 °C ambient, the junction reaches ~117 °C - well within the 150 °C maximum. No external heatsink is required.

Do not connect the GND1 and GND2 planes together on the PCB - this defeats the isolation barrier and can create a safety hazard as well as inject ground-loop noise into the data channels. Use the DIS pin (pin 21) to shut down the DC-DC converter when not needed for low-power standby modes; pulling DIS high reduces quiescent current to under 1 mA. Verify the VISO output voltage under worst-case load transients - some applications require an external 10-22 µF tantalum or polymer cap in parallel with the ceramic to suppress output ripple during load steps.

Compliance Information

RoHS
Compliant
REACH
Compliant
AEC-Q100
Not Qualified
Lead Free
Yes
Halogen Free
Yes
Conflict Minerals
Compliant

RoHS and REACH compliance per Abacus Technologies part listing. UL 1577 recognized component for 2500 Vrms isolation (60 seconds). Wide-body 24-SSOP meets IEC 60950-1 / IEC 61010-1 reinforced-insulation creepage. Not AEC-Q100 qualified - for automotive applications choose AEC-Q100-grade alternative such as ADUM5412BRSZ-Q1 (if available) or external qualified isolator.

Data verified on: 2026-10-06 — data verified and curated by XAIPART's component engineering team

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Related Components & Terms

Analog Devices ADUM5412BRSZ ADUM5412BRSZ-RL7 ADUM5410BRSZ ADUM5411BRSZ ADUM6412BRSZ ADUM6411BRSZ iCoupler isoPower digital isolator isolated DC-DC converter interface IC galvanic isolation 24-SSOP UL 1577 IEC 60950-1 IEC 61010-1 CMTI common-mode transient immunity RoHS REACH reinforced insulation fieldbus RS-485
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