Microchip Technology

ATMEGA325-16MI - AVR 8-Bit MCU 16MHz 32KB Flash | Microchip

MPN: ATMEGA325-16MI βœ“ Active
In Stock Ships in 1-3 business days
2.7 V to 5.5 V Vdss 64-QFN / MLF (9x9 mm) with exposed pad Package 16 MHz Speed 32 KB (16K x 16) Memory
From $3.05 USD / Unit
MOQ: 1 |
Price updated: 2026-09-17
Volume Pricing
Qty Unit Price Extended
1 $4.62 $4.62
10 $4.16 $41.60
100 $3.71 $371.00
500 $3.34 $1,670.00
1,000 $3.05 $3,050.00
ℹ️ All prices are in USD

ATMEGA325-16MI Overview

The Microchip Technology (Atmel) ATMEGA325-16MI is an 8-bit AVR RISC microcontroller with 16MHz max clock speed, 32KB (16K x 16) In-System Programmable Flash, 1KB EEPROM, and 2KB SRAM, housed in a 64-pin QFN/MLF (9x9 mm) surface-mount package with exposed pad.

An 8-bit microcontroller (MCU) is a complete computing system on a single chip, combining a processor core, program memory, data memory, and peripherals such as timers, USARTs, and ADCs. The AVR ATmega family sits within the broader microcontroller hierarchy of embedded processors, positioned for cost-sensitive, general-purpose embedded control where a full 32-bit application processor is unnecessary. Microcontrollers like the ATMEGA325-16MI run bare-metal firmware or an RTOS and directly drive sensors, actuators, displays, and communication links.

Key features include the Advanced RISC architecture with 130 powerful instructions, most executing in a single clock cycle; 16 MIPS throughput at 16MHz; 54 programmable I/O lines; two 8-bit and two 16-bit timers/counters; a 10-bit ADC; USART serial interface; and SPI support. Operating voltage spans 2.7V to 5.5V, and the industrial temperature grade (suffix MI) covers -40C to +85C, suiting harsh environments.

Technically, the AVR core uses a Harvard architecture with separate program and data buses, enabling single-cycle instruction fetch and execution. In-System Programmable (ISP) Flash allows firmware updates on the assembled board via SPI, while boot-section self-programming supports field upgrades. JTAG boundary scan and on-chip debug simplify production test.

Typical applications include industrial automation controllers, consumer appliances, IoT sensor nodes, HVAC and metering systems, and embedded human-machine interfaces where 32KB of code space and 54 GPIO lines cover mid-complexity control tasks.

A key design consideration: at 5V and 16MHz the device runs at its rated maximums, so verify power budget and derating in high-temperature enclosures; the 2.7V to 5.5V range allows battery designs to run at reduced clock speeds for lower consumption.

This page synthesizes distributor pricing, drop-in alternatives, design notes, and application guidance not found in a single manufacturer datasheet, verified as of 2026-09-17.

Drop-in alternatives for ATMEGA325-16MI β€” same package, pin-to-pin compatible. Different-package parts requiring PCB rework are excluded.

Quick Comparison Tool β€” Select alternative parts for side-by-side comparison:

ATMEGA325-16MU

βœ… Drop-In
πŸ“¦ 64-QFN (9x9 mm)
commercial temperature grade 0C to +70C vs industrial -40C to +85C; identical die, pinout, and 16MHz/32KB configuration

πŸ“‹ Reference alternative (not in catalog)

ATMEGA325-16MUR

βœ… Drop-In ⚠️ 参数待ιͺŒθ―
Microchip Technology
πŸ“¦ 64-QFN (9x9 mm)
AVR Β· 8-Bit Β· 16 MHz Β· 32KB (16K x 16) Β· FLASH (ISP) Β· 1KB Β· 2KB Β· 4.5 V to 5.5 V

βœ“ In Stock

$3.28 / Unit

View Datasheet β†’

ATMEGA325P-16MI

βœ… Drop-In ⚠️ 参数待ιͺŒθ―
πŸ“¦ 64-QFN (9x9 mm)
picoPower-grade process variant, pin-for-pin compatible, lower active/sleep current than standard 325

πŸ“‹ Reference alternative (not in catalog)

ATMEGA325PA-16MI

βœ… Drop-In ⚠️ 参数待ιͺŒθ―
πŸ“¦ 64-QFN (9x9 mm)
picoPower technology with 1.8V minimum supply vs 2.7V (-33%), significantly lower sleep current; same pinout and peripherals

πŸ“‹ Reference alternative (not in catalog)

ATMEGA3250-16MU

βœ… Drop-In ⚠️ 参数待ιͺŒθ―
πŸ“¦ 64-QFN (9x9 mm)
adds second USART (2 vs 1) in same 64-QFN footprint; commercial temperature grade; register map largely compatible

πŸ“‹ Reference alternative (not in catalog)

ATMEGA645-16MU

βœ… Drop-In ⚠️ 参数待ιͺŒθ―
πŸ“¦ 64-QFN (9x9 mm)
doubles Flash to 64KB and SRAM to 4KB, same 64-QFN pinout; commercial grade

πŸ“‹ Reference alternative (not in catalog)

ATMEGA329-16MU

βœ… Drop-In ⚠️ 参数待ιͺŒθ―
πŸ“¦ 64-QFN (9x9 mm)
adds segment LCD controller but I/O count reduced (~53 vs 54); same 64-QFN package and 32KB/16MHz configuration

πŸ“‹ Reference alternative (not in catalog)

ATMEGA325-16MI Maximum Ratings & Electrical Characteristics

Core Architecture 8-bit AVR RISC
Max Clock Frequency 16 MHz
Program Memory (Flash) 32 KB (16K x 16)
EEPROM 1 KB
SRAM 2 KB
Operating Voltage Range 2.7 V to 5.5 V
Number of I/O 54 programmable I/O lines
Instructions 130 powerful instructions, most single-cycle
Timers/Counters Two 8-bit and two 16-bit
ADC 10-bit
Serial Interfaces USART, SPI, TWI (I2C-compatible)
Package 64-QFN / MLF (9x9 mm) with exposed pad
Mounting Type Surface Mount
Operating Temperature -40C to +85C (industrial)
ISP (In-System Programmable) Yes
JTAG / Debug JTAG boundary scan and on-chip debug
RoHS Status Compliant (Green per FindIC data)

ATMEGA325-16MI 64-qfn / mlf (9x9 mm) with exposed pad Pin Configuration Guide

Pin configuration for ATMEGA325-16MI (64-qfn / mlf (9x9 mm) with exposed pad package). This digital IC includes GPIO, communication interfaces (UART, SPI, I2C), and power pins. Refer to the manufacturer datasheet for alternate pin functions and configuration options. Essential for embedded system design and PCB layout.

64-qfn / mlf (9x9 mm) with exposed pad package pinout diagram for ATMEGA325-16MI

No detailed pinout data available for ATMEGA325-16MI.

Refer to the datasheet for full pin configuration.

Typical Applications

ATMEGA325-16MI is suitable for 6 applications: Industrial Automation Controllers, IoT Sensor Nodes, Consumer Appliance Control, Metering and HVAC Systems, Embedded HMI and Display Panels, Motor and Actuator Drive Boards.

🏭

Industrial Automation Controllers

The ATMEGA325-16MI fits industrial control nodes because its -40C to +85C industrial temperature grade and 5V noise immunity match the electrical environment of factory floors. With 54 programmable I/O lines, two 8-bit and two 16-bit timers, and a 10-bit ADC, one MCU can handle relay driving, quadrature encoder reading, and analog sensor acquisition in a single 64-QFN 9x9 mm footprint. The 32KB ISP Flash accommodates state-machine-heavy ladder-style firmware with headroom for boot-section field updates via self-programming. Used as a PLC I/O module or machine sub-controller, it exchanges status with a supervisory PLC over the USART or SPI at several hundred kbps. The exposed-pad QFN on a solid ground plane improves EMI behavior in switch-noise-rich cabinets, and the watchdog timer plus brown-out detection keep firmware deterministic through supply sag events typical of motor-start transients.

🧩

IoT Sensor Nodes

For battery- or bus-powered IoT sensor nodes, the ATMEGA325-16MI combines a 2.7V to 5.5V supply range with AVR sleep modes, allowing the node to sleep between measurement cycles and wake on timer or pin interrupt. The 10-bit ADC digitizes temperature, humidity, or voltage channels directly, while the USART links to a radio module or RS-485 transceiver for backhaul. The 1KB EEPROM stores calibration constants and node identity through power cycles without external memory. In a 9x9 mm 64-QFN package, the MCU adds minimal board area, and the industrial -40C to +85C rating suits outdoor and rooftop deployments. Designers needing the lowest sleep current should choose the pin-compatible ATMEGA325PA-16MI picoPower variant; the standard 325 remains a solid choice for bus-powered (5V/3.3V) gateways and mains-supplied nodes where sleep current is less critical.

πŸ”§

Consumer Appliance Control

Appliance control boards - washers, cooktops, air conditioners - require modest compute, many GPIO for buttons/relays, and low unit cost, exactly the profile of the ATMEGA325-16MI. Its 16MHz core executes button scanning, display multiplexing, and relay sequencing with ample margin, while 54 I/O lines frequently eliminate external port expanders, cutting BOM cost. The 32KB Flash holds menu logic, fault logs, and self-test routines; the 1KB EEPROM persists user settings and cycle counters across power interruptions. SPI or USART connects to LED/LCD drivers or a Wi-Fi add-on module in connected-appliance versions. The 2.7V to 5.5V range tolerates loosely regulated appliance supplies after a small LDO stage, and the industrial temperature suffix covers the hot interiors of cooking and laundry products. In-circuit ISP allows final firmware configuration on the production line without desoldering.

⚑

Metering and HVAC Systems

Utility submeters and HVAC zone controllers benefit from the ATMEGA325-16MI's combination of 10-bit ADC, 2KB SRAM for rolling data buffers, and EEPROM for accumulating energy totals that must survive outages. Timers generate precise gate intervals for pulse-counting energy inputs and PWM outputs for damper or valve actuation. The USART provides standard connectivity to M-Bus/RS-485 metering buses through a transceiver, and TWI (I2C) reads RTC and sensor chips for timestamped records. Operating over -40C to +85C, the part survives rooftop AHU enclosures and unheated meter cabinets. Firmware stored in 32KB ISP Flash leaves room for communication stacks plus tariff logic, while boot-section self-programming enables recalibration updates in the field. The 64-QFN exposed pad, bonded to ground, aids conducted-emission control demanded by metering EMC environments.

πŸ“Ί

Embedded HMI and Display Panels

Small human-machine interfaces - keypad-plus-display panels for machines and kiosks - map well onto the ATMEGA325-16MI. A third of the 54 I/O lines directly drive a multiplexed LED segment display or scan a 16-key matrix, while the USART feeds a character LCD or serial OLED module. At 16MHz the core sustains flicker-free multiplexing and debounced touch handling simultaneously. The 2KB SRAM buffers display frame data and menu structures, and 1KB EEPROM stores language selections and setpoints across power-down. The 64-QFN 9x9 mm package fits behind typical panel PCBs, and the industrial temperature rating handles enclosed panels that warm under backlight load. ISP in-circuit programming lets a single board design carry product-specific firmware flashed at end-of-line, simplifying inventory across product variants within the same family of panels.

βš™οΈ

Motor and Actuator Drive Boards

The ATMEGA325-16MI serves as the firmware brain for small brushed-DC and stepper drive boards. Its two 16-bit timers generate phase-correct PWM with resolution high enough for quiet motor control, and two 8-bit timers handle tachometer capture and system ticks. The 10-bit ADC samples current-sense shunts and potentiometer feedback for closed-loop speed or position regulation executed in the single-cycle AVR core at 16MHz - fast enough for kilohertz control loops in C. Direction and enable outputs, plus USART for a host command link, round out a one-chip controller. Brown-out detection and the watchdog protect against stall-induced overcurrent firmware lockups. Placed on a board with a discrete H-bridge driver stage, the 64-QFN MCU keeps logic and power sections spatially separated, and its -40C to +85C grade covers enclosed actuator housings in outdoor equipment.

What is the ATMEGA325-16MI?
The ATMEGA325-16MI is a Microchip Technology (Atmel) AVR 8-bit microcontroller with a 16MHz core, 32KB ISP Flash, 1KB EEPROM, 2KB SRAM, and 54 programmable I/O lines in a 64-QFN (9x9 mm) package. According to the ATmega325 datasheet and DigiKey product data, it operates from 2.7V to 5.5V and over an industrial temperature range of -40C to +85C, suiting embedded control applications such as industrial automation, appliances, and IoT nodes.
What is the operating voltage of ATMEGA325-16MI?
The ATMEGA325-16MI operates from a 2.7V to 5.5V supply, per Microchip USA product data. The maximum 16MHz clock rating applies at 5V operation; at lower supply voltages the maximum safe clock frequency is derated per the frequency-versus-voltage curve in the AVR datasheet. Systems running below 4.5V should verify clock derating, while 5V designs can exploit the full 16 MIPS single-cycle throughput of the AVR core.
How much Flash, EEPROM, and SRAM does the ATMEGA325-16MI have?
The ATMEGA325-16MI provides 32KB (16K x 16) of In-System Programmable Flash for program memory, 1KB of on-chip EEPROM for non-volatile data storage, and 2KB of internal SRAM for runtime variables, according to DigiKey and Mouser product listings. The ISP Flash supports firmware updates via SPI on the assembled board, while the boot-section self-programming feature enables field firmware upgrades without removing the MCU from the application PCB.
What package does ATMEGA325-16MI use and how many pins does it have?
The ATMEGA325-16MI is housed in a 64-pin QFN (also called MLF or VFQFN) package measuring 9x9 mm with an exposed pad, per DigiKey and Heisener product data. The exposed thermal pad on the PCB underside should be soldered to a grounded copper pour for reliable grounding and heat dissipation. The 64-pin count provides 54 general-purpose I/O lines plus power, ground, reset, XTAL, and JTAG pins.
What is the difference between ATMEGA325-16MI and ATMEGA325-16MU?
The two parts share the same die, 64-QFN/MLF package, and 16MHz speed; they differ only in temperature grade. The ATMEGA325-16MI is the industrial grade (-40C to +85C), while the ATMEGA325-16MU is commercial grade (0C to +70C). FindIC lists the MU variant as a direct replacement candidate. For designs exposed to cold or hot environments, specify the MI suffix; the MU suits cost-sensitive indoor consumer products.
ATMEGA325-16MI vs ATMEGA3250-16AU - which is better for industrial control?
Both are 16MHz ATmega MCUs with 32KB Flash; the key difference is the ATMEGA3250-16AU adds a second USART and is packaged in a 64-pin TQFP, while the ATMEGA325-16MI uses a 64-QFN (9x9 mm) package. Choose the 3250 when you need two independent serial ports; choose the 325-16MI for a smaller, lower-profile QFN footprint or when your existing PCB already carries the 64-QFN land pattern. Code written for the mega325 is largely portable to the mega3250.
What is the best drop-in replacement for ATMEGA325-16MI?
The closest drop-in replacements share the same 64-QFN (9x9 mm) pinout: the ATMEGA325-16MU (commercial temperature variant, identical die), the ATMEGA325P-16MI (picon-power process variant with pin-for-pin compatibility and lower power), and the ATMEGA325PA-16MI (picoPower low-power upgrade). All preserve the 32KB Flash, 2KB SRAM, and 54 I/O configuration, so no PCB rework is needed. Verify ordering codes with Microchip before substitution, as suffixes encode speed, temperature, and package.
Can ATMEGA325-16MI be used in battery-powered IoT applications?
Yes, with caveats. The ATMEGA325-16MI runs from 2.7V to 5.5V, allowing direct use with 3-cell alkaline or lithium supplies, and AVR sleep modes reduce current dramatically when clocked down. However, this is the standard (not picoPower) grade; for the lowest sleep currents, choose the pin-compatible ATMEGA325PA-16MI, which adds picoPower technology in the same 64-QFN package. At 16MHz the MCU consumes several mA, so firmware should aggressively use idle and power-down sleep modes between sensing events.
Where can I download the ATMEGA325-16MI datasheet PDF?
The ATMEGA325-16MI datasheet PDF is available from Microchip Technology's official website (microchip.com) under the ATmega325 product family page, and from datasheet aggregators such as alldatasheet.com, which hosts the original ATMEL 8-bit Microcontroller with In-System Programmable Flash document. The core datasheet covers the ATmega325/3250/645/6450 family, so pinout sections for the 64-QFN/MLF package apply directly to this MPN. Always verify the revision date on the downloaded document before design release.
Where can I find the ATMEGA325-16MI pinout for the 64-QFN package?
The 64-QFN (MLF) pinout for the ATMEGA325-16MI is defined in the Pin Configurations section of the ATmega325/3250 datasheet, with diagrams for the 64-lead TQFP and 64-pad QFN/MLF footprints. The QFN diagram shows port pins A through G (54 I/O total), VCC and GND pairs, RESET, XTAL1/XTAL2, and JTAG pins (TCK, TMS, TDO, TDI) arranged around the 9x9 mm body. Download the official PDF from Microchip to obtain exact pad coordinates for your PCB land pattern.
How do I program the ATMEGA325-16MI in-system?
Program the ATMEGA325-16MI in-system via its SPI interface using Microchip's ISP tools such as the Atmel-ICE, AVRISP mkII, or any compatible programmer, per the In-System Programming section of the datasheet. ISP requires access to the MOSI, MISO, SCK, RESET, and VCC/GND pins, so layout should bring these to a programming header. Alternatively, self-programming from a boot Flash section enables field firmware updates through USART without a hardware programmer.
Is ATMEGA325-16MI RoHS compliant and lead-free?
Yes, the ATMEGA325-16MI is a RoHS-compliant, lead-free device; FindIC and distributor data list the part as a GREEN industrial-grade MLF component. Microchip's standard product flow is lead-free and halogen-free for current suffixes. For specific regulatory certificates (RoHS/REACH declarations), download the compliance documents from Microchip's product page for the exact ordering code, since compliance is tracked per orderable part number rather than the base MPN.
What is the price of ATMEGA325-16MI?
Pricing for the ATMEGA325-16MI on XAIPART starts at $4.62 for 1 unit as of 2026-09-17, decreasing to approximately $3.05 at 1000-piece volume, based on current distributor data from sources such as DigiKey. Distributors stock the part (Heisener reported 6,192 pieces in stock), so availability is generally good, but quotes for large volumes vary; request a formal quote for production quantities to confirm current lead time and pricing tiers.
Where to buy ATMEGA325-16MI online?
The ATMEGA325-16MI can be purchased online from XAIPART (with tier pricing from $4.62 at qty 1), and from authorized distributors including DigiKey and Mouser, both of which list the Microchip ATMEGA325-16MI 64-QFN part with datasheets, inventory, and pricing. Independent stockists such as Heisener and Avaq also carry inventory, which is useful for urgent shortages, but authorized channels are recommended for production to guarantee traceability and counterfeit protection.
What are the key specifications of ATMEGA325-16MI that engineers should know?
Key ATMEGA325-16MI specifications: 8-bit AVR RISC core at 16MHz (16 MIPS, 130 single-cycle instructions); 32KB ISP Flash, 1KB EEPROM, 2KB SRAM; 54 programmable I/O lines; two 8-bit and two 16-bit timers; 10-bit ADC; USART, SPI, and TWI interfaces; 2.7V to 5.5V operation; -40C to +85C industrial range; 64-QFN 9x9 mm package with exposed pad. These parameters define it as a mid-range ATmega for general embedded control with strong I/O count.
Is there a Microchip ATmega equivalent with lower power for the ATMEGA325-16MI?
Yes. The ATMEGA325PA-16MI is the pin-compatible picoPower successor in the same 64-QFN package, offering the same 32KB Flash, 2KB SRAM, 54 I/O, and 16MHz 5V performance with significantly reduced sleep-mode currents and a wider supply range down to 1.8V. Microchip explicitly positions P-series parts as drop-in upgrades for existing ATmega325 sockets. For new designs targeting battery operation, the PA variant is generally the better choice at essentially the same footprint and cost.

Engineering reference data for ATMEGA325-16MI β€” comparison, design guidance, and compliance information.

Selection Guide

Choose the ATMEGA325-16MI when you need a 16MHz, 32KB AVR in a 64-QFN footprint with guaranteed -40C to +85C industrial operation - typical for factory, metering, and outdoor embedded hardware. Choose ATMEGA325-16MU for indoor consumer products where commercial temperature ratings suffice and cost can be trimmed. Choose ATMEGA325PA-16MI for battery-powered designs needing the 1.8V minimum supply and lowest sleep current on the same pinout. Choose ATMEGA3250-16MU when a second USART is required for dual serial links, at the cost of losing the industrial temperature rating. If firmware outgrows 32KB Flash or 2KB SRAM, the ATMEGA645-16MU doubles both memories in the identical 64-QFN socket. All listed alternatives require no PCB layout change, so selection is purely a parametric trade-off among temperature grade, power, peripherals, and memory.

Comparison with Alternatives

Parameter This Product ATMEGA325-16MU ATMEGA325P-16MI ATMEGA325PA-16MI ATMEGA3250-16MU ATMEGA645-16MU
Package 64-QFN / MLF (9x9 mm) 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same 64-QFN (9x9 mm) - same
Brand Microchip Technology (Atmel) Microchip Technology Microchip Technology Microchip Technology Microchip Technology Microchip Technology
Max Clock Frequency 16 MHz 16 MHz 16 MHz 16 MHz 16 MHz 16 MHz
Flash Memory 32 KB 32 KB 32 KB 32 KB 32 KB 64 KB
SRAM 2 KB 2 KB 2 KB 2 KB 2 KB 4 KB
Operating Voltage 2.7 V to 5.5 V 2.7 V to 5.5 V 2.7 V to 5.5 V 1.8 V to 5.5 V 2.7 V to 5.5 V 2.7 V to 5.5 V
Operating Temperature -40C to +85C (industrial) 0C to +70C (commercial) -40C to +85C (industrial) -40C to +85C (industrial) 0C to +70C (commercial) 0C to +70C (commercial)
USART Count 1 1 1 1 2 1

Key Differentiators

  • Industrial temperature grade in the QFN package (vs ATMEGA325-16MU)
  • Pin-compatible picoPower upgrade path (vs ATMEGA325PA-16MI)
  • Largest Flash option in the same socket (vs ATMEGA645-16MU)

Design Notes

The 64-QFN (9x9 mm) package has a large exposed pad under the die that must be soldered to a grounded copper pour via an array of thermal vias. Skipping the exposed-pad connection is the most common QFN assembly defect: it causes intermittent ground returns and poor thermal performance even when perimeter joints look perfect. Follow Microchip's QFN land-pattern guideline with a solder-mask-defined pad, and use a 4-6 via array (0.3 mm drills) in the pad center. X-ray or acoustic inspection is recommended for the first production run of QFN devices.

Decouple each VCC pin pair with 100 nF ceramic capacitors placed within 3 mm of the pin, plus one bulk 4.7-10 uF capacitor per board. The AVR draws current spikes on clock edges, and QFN packages expose less lead inductance to self-filter, so local decoupling matters more than in DIP designs. At 16MHz/5V operation the device runs at its rated maximum; verify brown-out detector setting (2.7V threshold for 5V systems) is enabled in the fuse configuration so firmware does not execute erratically during supply sag.

Fuse misconfiguration is the top field failure for ATmega parts: setting SPIEN disable, wrong clock source, or RSTDISBL can permanently lock out ISP programming. Always verify fuses with a programmer before release. Also note that PCINT/JTAG pins default to JTAG function on ATmega325 family parts in QFN packages; if those pins are needed as GPIO, clear the JTAGEN fuse or disable JTAG in software via the MCUCSR register twice within four clock cycles per the datasheet.

Compliance Information

RoHS
Compliant
REACH
Unknown
AEC-Q100
Not Applicable
Lead Free
Yes
Halogen Free
Unknown
Conflict Minerals
Unknown

FindIC lists ATMEGA325-16MI as GREEN industrial-grade MLF (RoHS-compliant). REACH, halogen-free, and conflict-minerals declarations should be pulled from Microchip's official compliance documents for the exact ordering code.

Data verified on: 2026-09-17 β€” data verified and curated by XAIPART's component engineering team

Related Searches

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Related Components & Terms

Microchip Technology Atmel ATMEGA325-16MI ATMEGA325-16MU ATMEGA325PA-16MI ATMEGA3250-16MU ATMEGA645-16MU AVR 8-bit microcontroller MCU RISC architecture In-System Programming (ISP) 64-QFN MLF package VFQFN RoHS AEC-Q100 10-bit ADC USART SPI TWI (I2C) picoPower industrial automation IoT sensor node quiescent power
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